#coronavirus treatment side effects

[truth4ourfreedom]

THE BENEFITS OF IVERMECTIN. IF YOU HAVE CANCER, FREQUENT COLD OR INFECTIONS, MUSCLE SHRINKAGE, CARDIAC ISSUES, CROHNS, HERPES, ETC.

The study was published in the Cureus Journal of Medical Science.  LET'S TALK ABOUT IVERMECTIN 1 – Ivermectin prevents the damage caused to RNA Vaccines.  2 – Ivermectin blocks the entry of Spike Protein into cells.  So, if the person was vaccinated with COVID, they have hope, they have a way to treat themselves through Ivermectin.  3 – Ivermectin is a treatment after Covid and after vaccination, it is an effective medicine in all phases of Covid 19, even before entering the cell, Ivermectin already destroys the virus in the blood.  It only has beneficial effects and no harmful effects in the treatment of the coronavirus.  4 – Ivermectin has a very powerful anti-inflammatory action against Coronavirus.  5 – Ivermectin has a powerful action for traumatic and orthopedic injuries, it strengthens muscles and has no side effects like corticosteroids.  6 – Ivermectin treats autoimmune ailments such as: rheumatoid arthritis, ankylosing spondylitis, fibromyalgia, psoriasis, Crohn's disease, allergic rhinitis.  7 – Ivermectin reduces the frequency of flu and colds.  8 – Ivermectin improves the immunity of cancer patients.  9 – Ivermectin treats Herpes Simplex and Herpes Zoster.  10 – Ivermectin reduces the frequency of sinusitis and diverticulitis.  11 – Ivermectin protects the heart in cardiac overload, in an embolism for example, it prevents cardiac hypoxia because it stimulates the production of basic energy so that the tissue is not destroyed and thus improves cardiac function.  12 – Ivermectin is antiparasitic.  13 – Ivermectin is anti-neoplastic (anti-cancer), it suppresses the proliferation and metastasis of cancer cells, only killing cancer cells and preserving healthy cells, improving the effectiveness of chemotherapy treatment, as it kills cancer cells resistant to chemotherapy, defeating the resistance to multiple chemotherapeutics that tumors develop, and combined with chemotherapy and/or anti-cancer agents, it provides an increase in the effectiveness of these treatments.  14 – Ivermectin is antimicrobial (bacteria and viruses), and increases immunity.  15 – Ivermectin reaches the Central Nervous System and regenerates the nerves.  16 – Ivermectin regulates glucose and insulin metabolism.  17 – Ivermectin regulates cholesterol metabolism.  18 – Ivermectin reduces liver fat in steatose.  19 – Ivermectin protects the liver exposed to insecticides.  20 – Ivermectin attacks the virus wherever it is, regardless of mutations.  21 – Ivermectin serves for the prevention and treatment of coronavirus, surprisingly.  Unproven efficacy is not of Ivermectin, but of vaccines.  22 – Ivermectin, used as a prophylactic agent, was associated with a significant reduction in infection, hospitalization and mortality rates due to COVID-19.  23 - Ivermectin does not attack the liver, since it is not metabolized in it, and if in the intestine, on the contrary, it protects the liver. 

BIG PHARMA DOES NOT WANT YOU TO KNOW THIS.THEY WANT TO SELL YOU THE EXPENSIVE MEDS THEY MAKE BILLIONS ON.

Please read, save and re-blog before Tumblr takes this down.

[beardedmrbean]

Hufvudstadsbladet writes that Alexander Stubb took Åland by storm during his first visit there as president on Tuesday.

Describing it as a "charm visit" the paper features a photo of a seemingly endless queue in the main square in the capital, Mariehamn, of people lined up to take selfies with the president.

Hufvudstadsbladet also points to a more serious side to the visit, writing that Stubb said exactly what the Ålanders wanted to hear — the demilitarised status of the autonomous region is not a problem, and that having reviewed Finland's defence plans for Åland, he sleeps well at night.

Iltalehti reports that the president's press conference in Mariehamn on Tuesday was mainly focused on current foreign and security policy issues.

Asked about his statements to the French newspaper Le Monde regarding possible peace talks between Ukraine and Russia, he stood by his position, stressing that any decision on whether or not to start a negotiation process is in Ukraine's hands.

In reference to the counter-attack by Ukraine in Kursk, Stubb said that Finland would not impose restrictions on the use of the arms it supplies to Ukraine.

"Ukraine has every right to defend itself within the framework of international law," said President Stubb.

Potential for sabotage

Several papers picked up on a report first published online on Tuesday afternoon by Helsingin Sanomat saying that the Finnish Security Intelligence Service (Supo) sees Finnish arms aid to Ukraine as a target of potential Russian sabotage.

This summer, Finland sent its 24th shipment of arms aid to Ukraine. Officials have not revealed any details about their content or, for example, the mode of shipment.

The total value of all defence materials sent from Finland to Ukraine now stands at 2.2 billion euros.

Helsingin Sanomat quotes Supo researcher Lotta Hakala as saying that there are no signs of anything unusual concerning the logistics, storage and transport of Finland's arms aid. However, Supo has now publicly said they are potential targets for sabotage.

Supo has also found no evidence of Russian involvement in recent break-ins and vandalism at some water processing facilities in Finland.

The Security Intelligence Service adds, though, that Russia is trying to influence public opinion in countries that support Ukraine in order to create a climate of fear and uncertainty aimed at eroding popular support for Ukraine.

Covid up, but most cases mild

The number of cases of coronavirus infection is on the rise in Finland, but according to the National Institute for Health and Welfare (THL) symptoms seem to be less severe than in the past, and people are less likely to seek hospital treatment.

Ilta-Sanomat looks at the situation after asking readers to tell the paper about their experiences with covid over the summer, and receiving more than 600 responses by early this week.

The vast majority of respondents said they had mild symptoms after being infected. The most common symptoms included fever, headache, fatigue, cough, runny nose and muscle aches.

This is all very similar to the effects of a common cold.

Around 30 covid deaths were recorded in Finland between June and July this year, compared with over 120 in the same period last year.

Ilta-Sanomat notes that THL specialists have said that for the elderly or others in poor health Covid, like other infections, can still pose a serious and require hospitalisation.

Urban legend debunked

Have you heard of the old lady who feeds bread crumbs to birds from a large bag in Helsinki's central park? The story goes that she wears a black coat and a black scarf in summer and winter and doesn't say a word. If anyone approaches her, she vanishes.

Or how about the treasure hidden under what is now the Laajasalo bridge, stashed away by Carl Olof Cronstedt, a Vice-Admiral in the Swedish Navy? Cronstedt surrendered what is now the Suomenlinna fortress to Russian besiegers in 1808, and the story goes that first, he hid a huge bribe that he received for raising a white flag.

These are a few of the urban legends Helsingin Uutiset mentions before delving into its own investigation of one more — a longstanding rumour that the Helsinki House of Culture is home to an infestation of venomous spiders.

It is a fact that sometime during the 1970s a few Chilean recluse spiders apparently hitched a ride in a crate from South America to Helsinki's Museum of Natural History and established a small colony in the building.

HU set out to find investigate whether there is any truth to claims that something similar happened at the House of Culture.

The facilities production manager, Antti Sarmanne, claims to have seen the spiders several times in well over 20 years on the job.

"I think they came long before me. The story goes that the spiders came to the House of Culture in the equipment of a foreign artist, or from an exhibition," he said.

A thorough search by HU of the cellar's nooks and crannies found spiders, and spiders of more than one species, but none of them exotic or venomous.

Chilean recluse spiders have not been seen outside the Natural History Museum, its curator Timo Pajunen assured HU. During the 1990s, a spider was sent from the House of Culture to the museum for identification and it turned out to be a common house spider.

Helsingin Uutiset's conclusion is that whispers of deadly creepy-crawlers in the House of Culture can safely be ignored.

[darkmaga-returns]

Extracts of the the Judge’s reasoning and analysis:

On November 4, 2020, Plaintiff Brianne Dressen received AstraZeneca’s experimental COVID vaccine as part of a clinical trial in Salt Lake County. 4 Velocity Clinical Research, Inc. (Velocity) administered the trial on AstraZeneca’s behalf. 5 Before receiving the inoculation, Dressen signed an informed consent form (ICF) that outlined her rights and responsibilities as a trial participant and disclosed possible side effects of the vaccine.6 Under the terms of the ICF, the parties agreed AstraZeneca would “reimburse[] for time and travel in the amounts of $125.00 per each completed study visit and $30.00 for each completed phone call.”7 The parties also agreed that a “study doctor” would “provide medical treatment or refer [Dressen] for treatment” if Dressen became ill or injured while participating in the study.8 Additionally, AstraZeneca disclosed that it had an insurance policy to “cover the costs of research injuries as long as [Dressen] followed [the] study doctor’s instructions.”9 AstraZeneca confirmed it would “pay the costs of medical treatment for research injuries, provided that the costs are reasonable, and [Dressen] did not cause the injury [her]self.”10 At the same time, the parties agreed federal law may limit Dressen’s right to sue for injuries caused by the vaccine: Due to the coronavirus public health crisis, the federal government has issued an order that may limit your right to sue if you are injured or harmed while participating in this COVID-19-related clinical study. If the order applies, it limits your right to sue the researchers, healthcare providers, any Sponsor or manufacturer or distributor involved with the Study. You may be prevented from making claims for injuries that have a causal relationship with the use of the investigational product in this Study, including, but not limited to, claims for death; physical, mental, or emotional injury, illness, disability, or condition; fear of physical, mental, or emotional injury, illness, disability, or condition, including any need for medical monitoring; and loss of or damage to property, including business interruption loss. However, the federal government has a program that may provide compensation to you or your family if you experience serious physical injuries or death. If funds are appropriated by Congress, compensation for injuries may be available to you under this Countermeasures Injury Compensation Program.11 Within an hour of receiving the vaccine, Dressen’s right arm began tingling.12 The sensation, a condition called paresthesia, soon spread to her right shoulder and left arm.13 Later the same day, Dressen began experiencing a host of other symptoms, including blurred vison, tinnitus, nausea, and sound sensitivity.14 Dressen first visited an emergency room three days after receiving the vaccine.15 The doctor who treated her diagnosed her with a “vaccine reaction.”16 She returned to the emergency room four days later, and the next day she visited a nurse practitioner at Utah Valley Neurological who diagnosed her with an “immunization reaction.”17 Thirteen days after receiving the vaccine, Dressen visited an otolaryngologist to seek care for “acute sensitivities to light and sound.”18 The doctor noted Dressen was suffering from “a likely side effect due to an increased immune response to the vaccine.”19

[covid-safer-hotties]

Also preserved in our archive

Listen at the first link!

The GIST

Recent studies suggest that a hypermetabolic state that damages the mitochondria results in a hypometabolic state in chronic fatigue syndrome (ME/CFS), long COVID, and fibromyalgia (FM). They also suggest that something in the blood, serum, or plasma is damaging the mitochondria in these diseases.

We’re not done with the mitochondria, though – far from it! Now we look at a bevy of recent long-COVID mitochondrial studies suggesting that mitochondrial dysfunction affects more than energy production and which illuminate what may have gone wrong in the mitochondria.

Muscle biopsies of 120 long-COVID patients who had ended up in the ICU found that a year later their muscles had higher levels of immune cells involved in tissue repair and reduced activity of the 2nd and fourth mitochondrial complexes. The authors concluded that there was “aberrant repair and altered mitochondrial activity in skeletal muscle.”

They couldn’t explain how a respiratory illness affected the muscles but a subsequent study did. A hamster model found that the coronavirus suppressed the genes associated with the muscle fibers, protein production, both sides of the mitochondrial energy production process (Krebs cycle and electron transport chain), and fat breakdown.

As it was doing that, it unleashed a barrage of inflammatory factors (IFN-α, IFN-γ, and TNF-α) which triggered a shift from relying mostly on aerobic energy production to the less effective process of anaerobic energy production (glycolysis).

The authors concluded that using treatments “that can boost mitochondrial functions, enhance protein synthesis, and inhibit protein degradation” may be useful for treating muscle fatigue in long COVID.

Next, a muscle study assessing “maximal fatty acid oxidation (MFO)” (i.e. energy produced by the breakdown of fats during exercise) found significantly reduced levels of fatty acid oxidation in long COVID and a “premature shift” from relying on fats to carbohydrates to powering their cells.

This was important because the body prefers to burn fats during exercise and because fats play key roles in both parts of the mitochondrial energy production process. The finding wasn’t so surprising, though. Problems with carnitine – which transports fatty acids into the mitochondria – have popped up in both long COVID and ME/CFS – suggesting that the fatty acids that power the mitochondria during exercise may not be getting into them.

A review paper asserted that increased free radical production (reactive oxygen species (ROS)) by the mitochondria both pushes the cell into a state of anaerobic energy production but also pushes the immune system to activate the inflammatory or innate immune response and away from the adaptive immune response that targets pathogens. This benefits the viruses by providing the substrates they need to grow and allows them to escape from the immune system.

Several researchers, including Avindra Nath, believe that the immune system tries to compensate for the impaired adaptive immune defense by ramping up the innate immune response. Nath believes this shift plays a central role in ME/CFS.

They proposed that treatments to boost mitochondrial functioning and reduce the production of mitochondrial reactive oxygen species (ROS) (free radicals) will be beneficial.

Lastly, a review asserted that the predominant view of the mitochondria as the main energy producers of the cell is misguided and incomplete. Harkening back to Naviaux’s characterization of the mitochondria as the primary threat-sensing part of the cell, the authors believe the mitochondria regulate the “physiological processes at the level of the cell, organ and organism”; i.e. the mitochondrial problems affect much more than low energy levels and fatigue.

A blog on red light/infrared light therapy – which could both boost mitochondrial health and antioxidant defenses – is coming up.

Full text at either link! There's a lot more than the gist

[skymedsstore]

THE BENEFITS OF IVERMECTIN. IF YOU HAVE CANCER, FREQUENT COLD OR INFECTIONS, MUSCLE SHRINKAGE, CARDIAC ISSUES, CROHNS, HERPES, ETC.

The study was published in the Cureus Journal of Medical Science.  LET'S TALK ABOUT IVERMECTIN 1 – Ivermectin prevents the damage caused to RNA Vaccines.  2 – Ivermectin blocks the entry of Spike Protein into cells.  So, if the person was vaccinated with COVID, they have hope, they have a way to treat themselves through Ivermectin.  3 – Ivermectin is a treatment after Covid and after vaccination, it is an effective medicine in all phases of Covid 19, even before entering the cell, Ivermectin already destroys the virus in the blood.  It only has beneficial effects and no harmful effects in the treatment of the coronavirus.  4 – Ivermectin has a very powerful anti-inflammatory action against Coronavirus.  5 – Ivermectin has a powerful action for traumatic and orthopedic injuries, it strengthens muscles and has no side effects like corticosteroids.  6 – Ivermectin treats autoimmune ailments such as: rheumatoid arthritis, ankylosing spondylitis, fibromyalgia, psoriasis, Crohn's disease, allergic rhinitis.  7 – Ivermectin reduces the frequency of flu and colds.  8 – Ivermectin improves the immunity of cancer patients.  9 – Ivermectin treats Herpes Simplex and Herpes Zoster.  10 – Ivermectin reduces the frequency of sinusitis and diverticulitis.  11 – Ivermectin protects the heart in cardiac overload, in an embolism for example, it prevents cardiac hypoxia because it stimulates the production of basic energy so that the tissue is not destroyed and thus improves cardiac function.  12 – Ivermectin is antiparasitic.  13 – Ivermectin is anti-neoplastic (anti-cancer), it suppresses the proliferation and metastasis of cancer cells, only killing cancer cells and preserving healthy cells, improving the effectiveness of chemotherapy treatment, as it kills cancer cells resistant to chemotherapy, defeating the resistance to multiple chemotherapeutics that tumors develop, and combined with chemotherapy and/or anti-cancer agents, it provides an increase in the effectiveness of these treatments.  14 – Ivermectin is antimicrobial (bacteria and viruses), and increases immunity.  15 – Ivermectin reaches the Central Nervous System and regenerates the nerves.  16 – Ivermectin regulates glucose and insulin metabolism.  17 – Ivermectin regulates cholesterol metabolism.  18 – Ivermectin reduces liver fat in steatose.  19 – Ivermectin protects the liver exposed to insecticides.  20 – Ivermectin attacks the virus wherever it is, regardless of mutations.  21 – Ivermectin serves for the prevention and treatment of coronavirus, surprisingly.  Unproven efficacy is not of Ivermectin, but of vaccines.  22 – Ivermectin, used as a prophylactic agent, was associated with a significant reduction in infection, hospitalization and mortality rates due to COVID-19.  23 - Ivermectin does not attack the liver, since it is not metabolized in it, and if in the intestine, on the contrary, it protects the liver. 

[sideshow-tornado]

My dad was diagnosed with Stage 4 Prostate Cancer in February 2020 (perfect timing from the universe if you remember a little thing called the Coronavirus pandemic which shut down the entire world a month later). If caught early prostate cancer is one of the more treatable cancers, usually involving surgery to remove the prostate.

My dad was not so lucky, and by his own admission had been ignoring symptoms and problems for a long time, so his disease was too advanced for that type of treatment and upon his initial diagnosis the cancer was spread to bones in his hips and ribs.

But he has a terrific oncologist, and had very good health benefits through his then employer the University of Texas, so they started him on a mixture of chemo and hormone therapy and he responded very well to it. It was definitely rougher at some points, the side effects making him very weak and sickly.

Over that first year of his cancer battle I had been preparing myself as much as I could mentally and emotionally to lose my father. But he got better and eventually they were able to take him off most treatments for up to six months at a time.

The last few months some of his test results were becoming concerning, so they had him do a full body scan on Monday this week to see if the cancer had spread anymore. Thankfully we just got the news today the cancer has not spread; so they will restart him on his six months on/six months off regiment and will be giving him a new medication that should have less side effects.

We had been told his chances of making it 5 years after the diagnosis were good, and he’s almost there. Making it to the ten years the odds are not as great, but we’re happy he’s still with us for now. And at least one of the loads bearing down on me in life right now feels a bit lighter.

[colinwilson11]

Oncology Precision Medicine Market To Showcase Strong Growth Owing To Rising Demand For Targeted Cancer Therapies

The Oncology Precision Medicine Market has been growing at a steady pace owing to the increasing prevalence of various types of cancers and the need for more effective treatment options. Oncology precision medicine or personalized cancer therapy involves the use of molecular diagnostic tools to identify specific genomic alterations in a patient's tumor which helps physicians select appropriate targeted therapies. Unlike conventional chemotherapy, precision medicine enables customized treatment based on a person's individual genetics, lifestyle and environment. Some key benefits of precision therapies include better treatment response rate, reduced side effects, and ability to target specific cancer mutations.

The Oncology Precision Medicine Market is estimated to be valued at US$ 130 Bn in 2024 and is expected to exhibit a CAGR of 8.9% over the forecast period 2024-2031.

Rising demand for targeted therapies and advancements in genomic profiling technologies are the major factors fueling the growth of this market.

Key Takeaways

Key players operating in the oncology precision medicine are AstraZeneca, Novartis, Pfizer, Bristol-Myers Squibb, and Roche. These companies are engaged in developing novel targeted therapies and combinational regimens of existing drugs.

Continued rise in cancer incidence globally is generating considerable demand for precision therapy approaches. According to WHO, cancer burden is expected to reach 27.5 million new cases and 16.3 million cancer deaths by 2040.

Technological advancements such as next-generation sequencing, bioinformatics and development of companion diagnostics have enabled robust molecular characterization of tumors, which is improving clinical outcomes of precision cancer treatments.

Market Trends

1. Personalized Immunotherapy - Advancements are being made to develop personalized cancer vaccines and immune checkpoint inhibitors tailored to an individual's genetic makeup and tumor mutations. This offers immense potential to enhance immunotherapies response rates.

2. Combinational Therapies - Given emergence of drug resistance, focus is shifting towards combination of targeted drugs and immunotherapies. Numerous ongoing clinical trials are evaluating safety and efficacy of precision therapy combinations.

Market Opportunities

1. Liquid Biopsy Applications - Non-invasive liquid biopsies offer promise for real-time tumor monitoring and detection of acquired resistance. Growing research on liquid biopsy mediated precision therapies can expand market opportunities.

2. Emerging Markets - Lower penetration of precision oncology in developing nations compared to developed countries presents significant scope for future market expansion.

Impact Of COVID-19 On Oncology Precision Medicine Market Growth

The COVID-19 pandemic has significantly impacted the growth of the oncology precision medicine market. In the initial phases, various restrictions imposed to curb the spread of infection disrupted the supply chain and halted clinical trials. Production and supply of critical ingredients used in targeted therapies and immunotherapies faced delays. This caused shortages of some molecular tests used for cancer diagnosis and tumor profiling.

However, with progress in vaccination and adaptation to new safety protocols, the market is recovering fast. Telehealth and digital platforms played a key role in continuing remote consultation and treatment supervision during lockdowns. This boosted demand for companion diagnostics and biomarkers to optimize targeted treatments. Partnerships between pharmaceutical companies and diagnostic labs expanded disease monitoring and management capacities.

Investments in genomic and artificial intelligence-driven research accelerated during the pandemic to develop effective precision approaches against coronavirus. This is rapidly expanding knowledge applicable to personalized oncology. Growing focus on treatment individualization as per immune response and risk factors will boost post-COVID growth. Affordability of localized molecular testing is improving with increased production capacities.

Geographical Regions With High Oncology Precision Medicine Market Concentration

North America accounts for the largest share of the oncology precision medicine market value currently. This is attributed to broader healthcare insurance coverage and early adoption of novel targeted and immunotherapies. Comprehensive biomarker testing and genomic profiling are routinely used for selecting the right treatment pathway in the US and Canada.

Western Europe is another major revenue generator with high acceptance of precision diagnosis and therapies. Government-funded universal healthcare and stringent regulatory approval mechanisms fosters innovation. Asia Pacific is emerging as the fastest growing regional market. Developing nations like China and India are making huge investments in advancing their precision oncology infrastructure and capabilities.

Geographical Region Witnessing Fastest Growth In Oncology Precision Medicine Market

Asia Pacific region is projected to witness the fastest growth in the oncology precision medicine market during the forecast period. This is owing to rising cancer incidence, growing healthcare expenditure, increasing public-private collaborations and regulatory reforms to facilitate novel diagnostics and therapies.

Countries like China, South Korea and Japan are rapidly building genomic and clinical trial capacities to meet domestic demand and emerge as global precision medtech hubs. India is promoting medical tourism with competitive costs and a large patient pool benefiting from access to targeted medicines. Initiatives to strengthen diagnostic labs, train oncologists and establish tech-driven research facilities will further accelerate APAC's market expansion.

Get more insights on this topic: https://www.ukwebwire.com/oncology-precision-medicine-market-is-estimated-to-witness-high-growth-owing-to-advancements-in-cancer-genomics/

Author Bio:

Alice Mutum is a seasoned senior content editor at Coherent Market Insights, leveraging extensive expertise gained from her previous role as a content writer. With seven years in content development, Alice masterfully employs SEO best practices and cutting-edge digital marketing strategies to craft high-ranking, impactful content. As an editor, she meticulously ensures flawless grammar and punctuation, precise data accuracy, and perfect alignment with audience needs in every research report. Alice's dedication to excellence and her strategic approach to content make her an invaluable asset in the world of market insights. (LinkedIn: www.linkedin.com/in/alice-mutum-3b247b137 )

What Are The Key Data Covered In This Oncology Precision Medicine  Market Report?

:- Market CAGR throughout the predicted period

:- Comprehensive information on the aspects that will drive the Oncology Precision Medicine 's growth between 2024 and 2031.

:- Accurate calculation of the size of the Oncology Precision Medicine  and its contribution to the market, with emphasis on the parent market

:- Realistic forecasts of future trends and changes in consumer behaviour

:- Oncology Precision Medicine  Industry Growth in North America, APAC, Europe, South America, the Middle East, and Africa

:- A complete examination of the market's competitive landscape, as well as extensive information on vendors

:- Detailed examination of the factors that will impede the expansion of Oncology Precision Medicine  vendors

FAQ’s

Q.1 What are the main factors influencing the Oncology Precision Medicine ?

Q.2 Which companies are the major sources in this industry?

Q.3 What are the market’s opportunities, risks, and general structure?

Q.4 Which of the top Oncology Precision Medicine  companies compare in terms of sales, revenue, and prices?

Q.5 Which businesses serve as the Oncology Precision Medicine ’s distributors, traders, and dealers?

Q.6 How are market types and applications and deals, revenue, and value explored?

Q.7 What does a business area’s assessment of agreements, income, and value implicate?

*Note: 1. Source: Coherent Market Insights, Public sources, Desk research 2. We have leveraged AI tools to mine information and compile it

[trandingpost1]

Covishield Side Effects: What You Need to Know After 2 Years

Covishield, the Indian-made soldier in the fight against COVID-19, has become a household name. Millions across the globe have received this vaccine, and with time comes the natural question: what about Covishield side effects two years down the line? This article delves deeper, exploring both the well-known short-term effects and navigating the murky waters of potential long-term concerns.

Short-Term Jitters: A Common Occurrence

The good news? Most reported Covishield side effects are like fleeting visitors, arriving shortly after vaccination and departing within a few days. These temporary inconveniences are your body's immune system kicking into gear, a sign the vaccine is doing its job. Here's a breakdown of these common short-term companions: - Injection Site Woes: A familiar ache or soreness at the injection site is a frequent guest. Think of it as a mild muscle strain that fades away within a day or two. - Feverish Discomfort: A slight fever is another guest you might encounter. This low-grade rise in body temperature is your immune system's response, easily managed with over-the-counter pain relievers. - Fatigue: The Post-Vaccination Slump: Feeling drained or sluggish is a common complaint. Don't fight it – listen to your body and prioritize rest and hydration. - Headache Hijinks: Let's face it, headaches are unwelcome visitors anywhere. The good news is, these post-vaccination headaches tend to be short-lived and resolve on their own. - Muscle Aches and Chills: A slight shiver or muscle soreness might join the party. These are usually short-lived and can be soothed with rest and over-the-counter pain relievers.

The Rare Blood Clot Risk: Knowledge is Power

Blood Clot or thrombus blocking the red blood cells stream within an artery or a vein 3D rendering illustration. Thrombosis, cardiovascular system, medicine, biology, health, anatomy, pathology concepts. While short-term effects are manageable, there's a very rare side effect associated with the AstraZeneca vaccine, including Covishield, called Thrombosis with Thrombocytopenia Syndrome (TTS). TTS involves blood clots developing in unusual locations along with a decrease in blood platelets. The risk of developing TTS is extremely low, estimated to be around 4-8 cases per million vaccinations. However, being aware of the signs and symptoms of TTS is crucial. These may include: - A persistent, worsening headache - Blurred vision or difficulty seeing - Difficulty breathing or chest pain - Leg swelling or pain - Persistent abdominal pain If you experience any of these symptoms after receiving the Covishield vaccine, seek immediate medical attention. Early diagnosis and treatment are key in managing TTS.

The Long-Term Landscape: Navigating Uncertainty

World of blue question mark. Elements of this image furnished by NASA. Since COVID-19 vaccines are a relatively new development, there's a lack of long-term data (beyond 2 years) on potential Covishield side effects. However, this doesn't necessarily translate to hidden risks. Extensive safety monitoring is ongoing by the World Health Organization (WHO) and other health organizations to assess the long-term safety of all COVID-19 vaccines, including Covishield.

Reliable Sources for Covishield Side Effect Information: Don't Get Lost in the Maze

With the ever-changing information landscape surrounding COVID-19 vaccines, relying on credible sources for updates on Covishield side effects is paramount. Here are some trustworthy resources you can consult: - World Health Organization (WHO): https://www.who.int/news-room/feature-stories/detail/the-oxford-astrazeneca-covid-19-vaccine-what-you-need-to-know - Centers for Disease Control and Prevention (CDC): https://www.cdc.gov/coronavirus/2019-ncov/vaccines/index.html

When in Doubt, Talk it Out: Consulting Your Healthcare Professional

If you have any specific concerns related to Covishield side effects after receiving the vaccine, consult a healthcare professional. They can address your individual questions and concerns based on your medical history and any specific symptoms you may be experiencing.

The Final Word: Knowledge is Power

Covishield has been a crucial weapon in the fight against COVID-19. While most reported Covishield side effects are short-term and mild, it's important to be aware of the rare blood clot risk (TTS) and to seek immediate medical attention if you experience any concerning symptoms. The lack of long-term data beyond two years doesn't necessarily indicate long-term risks, and ongoing monitoring efforts by health organizations are in place. For the most up-to-date and reliable information on Covishield side effects, consult trustworthy health resources or schedule an appointment with your doctor. Read the full article

[mihikavasant]

Covid Tongue - The new symptom of coronavirus infection

The globe has seen several unexpected developments since the Corona pandemic began. Even minor physical symptoms during the pandemic, such as a fever, headache, or dry cough, might cause people to become anxious and nervous.

COVID Tongue is one of the less well-known COVID-19 symptoms that has to do with oral health. This illness is characterized by peculiar rashes, especially on the tongue and toes, and a decreased sensation of taste.

COVID-19 The tongue appears as lumps and enlargements on the outside, frequently with dark or red areas that mimic a geographic tongue. Those who experience weariness and headaches in addition to these abnormalities in the tongue should be on the lookout for signs of a coronavirus infection.

It is commonly known that mucous membranes, including the tongue, are susceptible to bacterial infection. Studies reveal that ACE (Angiotensin-Converting Enzyme) is abundantly present on the tongue's surface and acts as the coronavirus's main site of attachment. As a result, the virus may spread and infect people, which could result in COVID Tongue.

COVID-19 treatment The etiology of tongue is yet unknown, thus it continues to be elusive. It is important to remember that dental disorders other than COVID-19 can cause abnormalities of the tongue and discomfort in the mouth. However, it's critical to see a doctor right away to rule out COVID-19 infection if accompanied by symptoms like exhaustion, coughing, and shortness of breath.

If a person tests positive for COVID-19, they will be given individualized treatment plans, recommended drugs, and instructions on how to follow quarantine rules to treat the virus and its side effects, such as abnormalities in the tongue.

It is important to stress that maintaining good hygiene habits, such often washing your hands, sterilizing them, donning masks, and keeping social distance from others, is still essential to preventing the transmission of COVID-19 and its oral manifestations. Although vaccinations provide hope, questions remain about how the virus may affect people's health in the long run.

In conclusion, being watchful and following advised precautions will help protect against COVID Tongue and other possible side effects of the infection.

FOR MORE INFO PLEASE VISIT : https://www.suryadentalcare.com/covid-tongue-the-new-symptom-of-coronavirus-infection/

[pharmanucleus1]

Global Osteoarthritis Market: Trends, Treatment, and Projections 2030

Report Summary 

In 2023, the worldwide osteoarthritis market was valued at USD 7.40 billion and is predicted to increase at an 8.5% CAGR during the forecast period 2023-2030. Both the introduction of analgesic drugs and the development of imaging diagnostics based on radiographic characteristics are stimulating market growth. Increased expenditure on healthcare infrastructure and expanding investments in research and development (R&D) efforts to bring novel diagnostics and biomarkers are also driving the market. 

Osteoarthritis (OA) is a group of disorders that affect the joints of the knees, hips, fingers, foot, back, shoulders, and neck. It is distinguished by the gradual degeneration of the cartilage in these joints. Stiffness, edoema, discomfort, persistent pain, loss of flexibility, a grating sensation, bone spurs, and sleep interruptions are all common symptoms of OA. 

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Medical examination, X-rays, arthroscopy, joint fluid analysis, lab testing, and magnetic resonance imaging (MRI) scans can all be used to diagnose it. Depending on the outcomes, different medications and surgical techniques are prescribed to treat the disease's signs and symptoms. There are presently alternative medicines, physical therapy, and supporting devices on the market to relieve pain and improve joint function. 

Sedentary lifestyles, poor eating habits, and increasing weight and blood sugar levels make people more susceptible to develop OA. This is one of the primary driving drivers for market development, combined with an ageing population that is more susceptible to such disorders. Furthermore, the ease of access to MRI scans is a key growth-promoting factor. 

The COVID-19 outbreak is predicted to have only a minimal influence on the osteoarthritis therapy industry. Corticosteroids are being used less often in many medicine types. Although there is no evidence that corticosteroid injections significantly increase the risk of infection, the immune system may be less active for a few weeks following surgery. 

Even though the risk is extremely minimal, it should be taken into account before starting with the procedure. It should be noted that the World Health Organisation cautioned against the use of systemic corticosteroids in one of its guidelines for treating severe acute respiratory infections caused by coronavirus. 

Industry Dynamics 

Growth Drivers:  

Increased government investment on cell-based research, as well as the increasing use of opioids, are driving market expansion. Topical, oral, and analgesic medications are commonly used to treat osteoarthritis pain. Even if alternatives such as orthopaedic braces are used as part of a noninvasive approach to pain therapy, the adoption of pain pills for the disease is substantial due to the ease of administration and the cost of pain medications. Oral analgesics such as acetaminophen, NSAIDs, intra-articular medicines, and nutraceuticals are all common pain relievers. 

Personalised OA medications have also been proposed, which would represent a considerable advance in the diagnosis, therapy, and monitoring of disease severity in osteoarthritis patients. Simple measurement, appropriate levels of sensitivity and specificity, and test procedures available to and interpretable by clinicians are critical qualities of indicators of therapeutic relevance for a personalised approach to OA therapy. 

The use of biomarkers to identify individuals who are most likely to respond to specific medical therapies may increase treatment response rates and reduce the risk of exposing patients to medicines that are either unlikely to be effective or may cause harmful side effects from their treatment. Using a mix of unique biomarkers and baseline clinical parameters such as age and gender might be beneficial. 

Report Segmentation 

The market is primarily segmented based on treatment type, disease type, distribution channel, route of administration, and region. 

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Knee Osteoarthritis segment is expected to witness fastest growth 

Personalised OA medications have also been proposed, which would represent a considerable advance in the diagnosis, therapy, and monitoring of disease severity in osteoarthritis patients. Simple measurement, appropriate levels of sensitivity and specificity, and test procedures available to and interpretable by clinicians are critical qualities of indicators of therapeutic relevance for a personalised approach to OA therapy. 

Furthermore, increased FDA approvals for the treatment of Knee OA are driving sector growth throughout the projection period. For example, Novartis announced in September 2021 that LNA043 had been granted fast-track designation by the US Food and Drug Administration (FDA) for knee osteoarthritis rehabilitation. 

Drugs targeted to treat severe diseases and address unmet medical needs can be created more swiftly and evaluated more quickly. LNA043, a possibly first-in-class disease-modifying treatment for osteoarthritis, is being developed. As a result, growing approvals for the treatment of knee OA drive market development throughout the projection period. 

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Viscosupplementation segment industry accounted for the highest market share in 2021 

The rising prevalence of knee osteoarthritis is the key driver of this market's expansion. By injecting synovial fluid into the afflicted joints, which increases lubrication, viscosupplementation greatly lowers osteoarthritis discomfort. Furthermore, the market for viscosupplementation agents is expected to grow considerably over the forecast period due to the discovery of novel viscosupplementation agents and government efforts to boost research in the healthcare sector. 

Hospital Pharmacies are expected to hold the significant revenue share 

Hospital pharmacies retained the largest share of this market due to the large number of patients seeking treatment for osteoarthritis in hospitals and the vast assortment of osteoarthritis drugs available in these pharmacies. Another important advantage is the ease with which hospital pharmacy purchases may be reimbursed. 

The demand in North America is expected to witness significant growth 

A rise in the frequency of chronic diseases, an increase in the number of elderly people, and changes in people's lifestyles all contribute to the anticipation of market expansion in North America. As a result, the region is incorporating an increasing number of treatments and drugs. When compared to Canada and Mexico, the United States will command a substantial share of the North American market for osteoarthritis therapies. 

According to the CDC, osteoarthritis (OA), the most common kind of arthritis, is a severe chronic illness that affects 32.5 million individuals in the United States. OA is associated with ageing and is more common in those with other chronic conditions such as obesity, diabetes, and heart disease. However, 18.7 million people with OA, or more than half of them, are of working age (18 to 64 years). 

Furthermore, the availability of better treatment alternatives, government reimbursement guidelines, increased research and development activities in the creation of novel medicines, and the introduction of new therapies in the North American region are all expected to support market expansion in the region. 

Europe controlled the market for osteoarthritis therapies. The increased incidence of osteoarthritis, the ageing population, rising obesity rates in several European countries, and the growing number of sports- and accident-related injuries all contribute to this sector's large market share. 

[legendaryturtletheorist]

Exploring the Frontiers of Science: Lung Cell Culture and its Implications in Research and Medicine

Introduction:

Lung cell culture, a sophisticated technique in cell biology, plays a pivotal role in advancing our understanding of respiratory diseases, drug development, and personalized medicine. This technique involves the extraction and cultivation of lung cells outside the body in a controlled environment, providing researchers with a powerful tool to study cellular processes, test new drugs, and develop innovative therapies. In this article, we will delve into the intricacies of lung cell culture, its applications, and the profound impact it has on scientific research and medical advancements.

Fundamentals of Lung Cell Culture:

Lung cell culture begins with the isolation of cells from lung tissues, either from animal models or human donors. The cells are then placed in a nutrient-rich medium that mimics the conditions found within the body. This artificial environment supports the cells' growth, allowing them to proliferate and form a monolayer or three-dimensional structures, depending on the research goals.

Primary cells, derived directly from tissues, and immortalized cell lines, which can divide indefinitely, are the two main types of cells used in lung cell culture. Primary cells are preferred when studying specific physiological processes, while immortalized cell lines provide a consistent and reproducible platform for large-scale experiments.

Applications of Lung Cell Culture:

Disease Modeling:

Lung cell culture has revolutionized the modeling of respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), and lung cancer. By culturing cells from affected individuals or utilizing genetically modified cells, researchers can recreate disease conditions in vitro. This allows for the study of disease mechanisms, identification of potential therapeutic targets, and the development of more effective treatments.

Drug Discovery and Development:

The pharmaceutical industry heavily relies on lung cell culture for drug discovery and development. Testing potential drugs on cultured lung cells provides valuable insights into their efficacy, toxicity, and potential side effects. This step is crucial in the early stages of drug development, helping researchers identify promising candidates and eliminate those with unfavorable characteristics before moving to expensive and time-consuming clinical trials.

Infection Studies:

Lung cell culture is instrumental in studying respiratory infections caused by viruses, bacteria, and fungi. Researchers can infect cultured cells with pathogens to understand the host-pathogen interactions, immune responses, and the development of antiviral or antibacterial therapies. This approach has been particularly valuable in the study of respiratory viruses such as influenza and the coronavirus.

Toxicology Studies:

Evaluating the toxic effects of various substances on lung cells is another important application. Researchers can expose cultured cells to pollutants, chemicals, or other environmental factors to assess their impact on cellular function and viability. This information is crucial for understanding the potential risks associated with exposure to different substances and for establishing safety guidelines.

Stem Cell Research:

Lung cell culture is also integral to stem cell research aimed at regenerative medicine. By manipulating stem cells in culture, researchers can guide their differentiation into specific lung cell types. This approach holds promise for repairing damaged lung tissue and developing cell-based therapies for conditions like pulmonary fibrosis.

Challenges and Future Directions:

While lung cell culture has significantly advanced our understanding of respiratory biology, it comes with its own set of challenges. Culturing cells in an artificial environment may not fully replicate the complex interactions and conditions present in the human body. Researchers continually strive to improve culture systems to better mimic in vivo environments, incorporating factors like airflow, mechanical strain, and the three-dimensional architecture of lung tissue.

Moreover, the heterogeneity of lung cell populations adds another layer of complexity. Different cell types, including alveolar epithelial cells, bronchial epithelial cells, and immune cells, each have distinct characteristics. Researchers are working to develop more specialized culture techniques that account for this diversity, allowing for more precise and meaningful experiments.

As technology advances, lung cell culture is likely to become even more sophisticated. The integration of microfluidics, 3D bioprinting, and organ-on-a-chip technologies holds promise for creating in vitro models that closely resemble the complex structure and function of the human lung. These innovations could enhance the accuracy of drug testing, disease modeling, and toxicology studies, bringing us closer to personalized medicine tailored to individual patient profiles.

Conclusion:

Lung cell culture stands at the forefront of scientific and medical research, offering a versatile platform for studying respiratory diseases, testing drugs, and advancing regenerative medicine. Its applications extend across a spectrum of disciplines, from basic cellular biology to drug discovery and development. Despite the challenges, researchers continue to refine and innovate in the field, pushing the boundaries of what is possible.

As our understanding of lung cell biology deepens and technology continues to evolve, the impact of lung cell culture on healthcare and medicine is likely to expand. This technique holds the key to unlocking new insights into respiratory diseases, paving the way for more effective treatments and personalized therapeutic approaches.

[periwinklemeanderings]

Vitamin C (Ascorbic Acid) - Uses, Side Effects, And More

Possibly Ineffective for

Short-term swelling (inflammation) of the airways in the lungs (acute bronchitis). Taking vitamin C by mouth does not seem to have any effect on bronchitis.

Asthma. Taking vitamin C by mouth doesn't seem to prevent asthma or improve symptoms in people who already have asthma.

Hardening of the arteries (atherosclerosis). Taking vitamin C by mouth does not seem to prevent atherosclerosis from becoming worse in most people with this condition.

Bladder cancer. Taking vitamin C by mouth does not seem to prevent bladder cancer or reduce bladder cancer-related deaths.

Heart disease. Taking vitamin C by mouth does not prevent heart disease or reduce death due to heart disease.

Colon cancer, rectal cancer. Taking vitamin C by mouth does not seem to prevent cancer in the colon or rectum.

Coronavirus disease 2019 (COVID-19). Taking high-dose vitamin C by mouth does not seem to speed up recovery from COVID-19 in people who aren't in the hospital. Giving vitamin C by mouth or IV to people who are in the hospital with severe COVID-19 might have some benefit, but more studies are needed to say for sure.

Death of an unborn or premature baby. Taking vitamin C by mouth, alone or with other supplements, during pregnancy doesn't prevent death of an unborn or premature baby.

Fractures. Taking vitamin C by mouth does not seem to improve function, symptoms, or healing rates in people with a wrist fracture.

A digestive tract infection that can lead to ulcers (Helicobacter pylori or H. pylori). Taking vitamin C by mouth along with medicines used to treat H. pylori infection doesn't seem to get rid of H. pylori faster than taking the medicines alone.

A group of inherited disorders that leads to muscle weakness and numbness in the arms and legs. Taking vitamin C by mouth for one or two years does not seem to prevent nerve damage in people with these disorders.

Eye damage in people taking drugs called interferons (interferon-related retinopathy). Taking vitamin C by mouth does not seem to prevent eye damage in people receiving interferon therapy for liver disease.

Cancer of the white blood cells (leukemia). Taking vitamin C by mouth doesn't seem to prevent leukemia or death due to leukemia.

Lung cancer. Taking vitamin C by mouth, alone or with vitamin E, doesn't seem to prevent lung cancer or death due to lung cancer.

The most serious type of skin cancer (melanoma). Taking vitamin C by mouth, alone or with vitamin E, doesn't prevent melanoma or death due to melanoma.

Miscarriage. Taking vitamin C by mouth, alone or with other supplements, during pregnancy does not prevent miscarriage.

Death from any cause. Taking vitamin C by mouth along with other antioxidants does not seem to prevent death.

Pancreatic cancer. Taking vitamin C by mouth together with beta-carotene plus vitamin E does not seem to prevent pancreatic cancer.

A pregnancy complication marked by high blood pressure and protein in the urine (pre-eclampsia). Taking vitamin C by mouth with vitamin E during pregnancy does not prevent high blood pressure and protein in the urine during pregnancy.

Preterm birth. Taking vitamin C by mouth, alone or with other supplements, during pregnancy does not prevent preterm birth.

Prostate cancer. Taking vitamin C by mouth does not seem to prevent prostate cancer.

Skin damage caused by radiation therapy (radiation dermatitis). Applying a vitamin C solution to the skin does not prevent skin problems caused by radiation treatments.

Infants with birth weight below the 10th percentile. Taking vitamin C by mouth, alone or with other supplements, during pregnancy does not reduce the chance of giving birth to an infant with a low birth weight.

Stillbirth. Taking vitamin C by mouth, alone or with other supplements, during pregnancy does not reduce the chance of having a stillbirth.

There is interest in using vitamin C for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.

Likely InEffective for

Blood infection (sepsis). Giving vitamin C by IV with or without thiamine and/or a steroid does not reduce the risk of dying, organ damage, hospitalization duration, or the need for supportive treatment in people with sepsis. -

[pranay-234]

Amoxicillin Market Recent Advancements and Future Challenges

The Amoxicillin market, a vital component of the global pharmaceutical landscape, is poised for significant growth and transformation by 2032. This article explores the top winning strategies that will shape the future of the Amoxicillin market and its role in addressing infectious diseases and improving global healthcare.

𝐑𝐞𝐪𝐮𝐞𝐬𝐭 𝐒𝐚𝐦𝐩𝐥𝐞 𝐂𝐨𝐩𝐲 𝐎𝐟  𝐑𝐞𝐩𝐨𝐫𝐭 : https://www.alliedmarketresearch.com/request-toc-and-sample/11484

COVID-19 scenario analysis:

The Pharmaceutical and biotech companies have joined together with governments around the globe in order to manage COVID-19 outbreak, from supporting the development of vaccines to planning for medicines supply chain challenges. Furthermore there is various development initiatives carried out such that around 115 vaccine candidates and 155 molecules are expected to help in management of coronavirus disease -2. Moreover, the drugs which are successfully showing its effect on the patient such as Hydroxychloroquine have witnessed dramatic surge in demand for the management of COVID-19. The high demand for these drugs has presented huge opportunity for manufacturers of COVID-19 management drugs, as many developed countries are short of these drugs. The rise in demand for vaccine and treatment drugs for COVID-19, the pharmaceutical and biotechnology industry is expected to witness a significant growth in the future.

1. Research and Development Advancements

One of the cornerstones of the Amoxicillin market's future success is the continued investment in research and development. Pharmaceutical companies are committed to enhancing the efficacy and safety of Amoxicillin formulations, potentially reducing side effects and improving patient compliance. This includes exploring novel delivery methods, combination therapies, and the development of pediatric formulations to make Amoxicillin more accessible for children.

2. Focus on Generic Variants

As patents for branded Amoxicillin products expire, generic variants will play a pivotal role in expanding market reach. Generic drug manufacturers will employ strategies to produce cost-effective versions of Amoxicillin, making the medication more affordable and accessible to a broader population.

3. Antibiotic Stewardship Initiatives

The rise of antibiotic resistance has heightened the importance of responsible antibiotic use. Pharmaceutical companies and healthcare providers are embracing antibiotic stewardship programs to promote the rational use of antibiotics like Amoxicillin. By ensuring the right antibiotic is prescribed for the right duration and at the right dose, the industry aims to combat resistance and prolong the effectiveness of these critical medications.

𝐏𝐫𝐞-𝐛𝐨𝐨𝐤 𝐭𝐡𝐢𝐬 𝐑𝐞𝐩𝐨𝐫𝐭 𝐍𝐨𝐰 : https://www.alliedmarketresearch.com/amoxicillin-market/purchase-options

4. Global Market Expansion

The Amoxicillin market is extending its reach globally, with a focus on emerging markets. As healthcare infrastructure improves in developing countries, the demand for antibiotics, including Amoxicillin, is expected to grow. Companies are formulating strategies to meet this increasing demand, ensuring a stable supply of antibiotics where they are most needed.

5. Sustainable Practices

Pharmaceutical companies are increasingly adopting sustainable and environmentally responsible practices in the production and distribution of Amoxicillin. Reducing waste, conserving resources, and adopting eco-friendly packaging options are part of the industry's broader sustainability efforts.

6. Education and Awareness

Education and awareness campaigns are key components of the winning strategies for the Amoxicillin market. These efforts target both healthcare professionals and the public, aiming to raise awareness about responsible antibiotic use, the importance of completing prescribed courses, and the dangers of self-medication.

7. Regulatory Compliance

Adherence to stringent regulatory standards and quality control measures is paramount in the Amoxicillin market. Companies are committed to ensuring product quality and safety, meeting international regulatory requirements, and maintaining Good Manufacturing Practices (GMP).

Inquire Before Buying : https://www.alliedmarketresearch.com/purchase-enquiry/11484

In conclusion, the Amoxicillin market by 2032 will be characterized by responsible antibiotic use, enhanced formulations, increased accessibility, and a stronger commitment to sustainability. These winning strategies are not only reshaping the industry but also contributing to the global fight against infectious diseases and antibiotic resistance, ensuring that Amoxicillin remains a critical tool in modern healthcare. The future of Amoxicillin holds promise, not just for the pharmaceutical industry but for public health on a global scale.

About Us

Allied Market Research (AMR) is a full-service market research and business-consulting wing of Allied Analytics LLP based in Portland, Oregon. Allied Market Research provides global enterprises as well as medium and small businesses with unmatched quality of "Market Research Reports" and "Business Intelligence Solutions." AMR has a targeted view to provide business insights and consulting to assist its clients to make strategic business decisions and achieve sustainable growth in their respective market domain.

Pawan Kumar, the CEO of Allied Market Research, is leading the organization toward providing high-quality data and insights. We are in professional corporate relations with various companies and this helps us in digging out market data that helps us generate accurate research data tables and confirms utmost accuracy in our market forecasting. Each and every data presented in the reports published by us is extracted through primary interviews with top officials from leading companies of domain concerned. Our secondary data procurement methodology includes deep online and offline research and discussion with knowledgeable professionals and analysts in the industry.

[rupeshlunkad]

Unraveling the Web of Digestive Disorders: Insights from Dr. Rupesh Lunkad, Best Gastroenterologist in Pune

Introduction

In the intricate orchestra of our bodily functions, the digestive system plays a pivotal role. However, it's not always smooth sailing. Many individuals find themselves grappling with various digestive disorders that can disrupt daily life. To shed light on these common issues, we turn to Dr. Rupesh Lunkad, recognized as the best gastroenterologist in Pune, whose expertise has unraveled the mysteries of digestive health for countless patients.

Understanding Digestive Disorders

Digestive disorders encompass a wide spectrum of conditions that affect the gastrointestinal (GI) tract. From mild inconveniences to severe health issues, these disorders can manifest in diverse ways, making early recognition and intervention crucial.

Dr. Lunkad emphasizes the value of recognizing side effects and seeking appropriate therapeutic advice. Stomach-related problems can range from simple cases of heartburn to more complicated ones like inflammatory bowel disease (IBD) or irritable bowel syndrome (IBS). Every case is unique, and a tailored approach to conclusion and treatment is essential.

Common Digestive Disorders

Gastroesophageal Reflux Disease (GERD): GERD is a chronic condition where stomach acid flows back into the esophagus, causing symptoms like heartburn and regurgitation. Dr. Lunkad highlights lifestyle modifications and medications as key components of managing GERD.

Irritable Bowel Syndrome (IBS): IBS is a functional GI disorder characterized by abdominal pain, bloating, and changes in bowel habits. Dr. Lunkad emphasizes the role of a balanced diet, stress management, and medications tailored to individual symptoms in managing IBS.

Inflammatory Bowel Disease (IBD): Crohn's disease and ulcerative colitis are two types of IBD that cause chronic inflammation in the digestive tract. Dr. Lunkad stresses the importance of a multidisciplinary approach, including medications, nutritional therapy, and, in some cases, surgery.

Celiac Disease: An autoimmune disorder triggered by gluten consumption, celiac disease can damage the small intestine. Dr. Lunkad underscores the necessity of a strict gluten-free diet and nutritional support for those with celiac disease.

Peptic Ulcers: Open sores that develop on the inner lining of the stomach, small intestine, or esophagus, peptic ulcers can cause pain and discomfort. Dr. Lunkad discusses the role of medications to reduce stomach acid, antibiotics for H. pylori infection, and lifestyle changes in managing peptic ulcers.

Prevention and Lifestyle Modifications

Preventing digestive disorders often involves adopting healthy lifestyle habits. Dr. Lunkad advises a balanced diet rich in fiber, regular exercise, adequate hydration, and stress management. "These lifestyle modifications are not only essential for preventing digestive issues but also play a crucial role in managing existing conditions," he emphasizes.

The Importance of Regular Check-ups

Maintaining stomach-related health requires routine visits to a gastroenterologist. In particular for people who have a family history of digestive problems or who are suffering from severe side effects, Dr. Lunkad suggests routine testing. "Early location can altogether affect the course of treatment and work on long haul results," he said.

Navigating the Future of Digestive Health

As innovation propels, so does the area of gastroenterology. Dr. Lunkad examines the job of imaginative symptomatic apparatuses and medicines in forming the eventual fate of stomach related medical care. " Progressions like virtual colonoscopies, container endoscopies, and negligibly obtrusive strategies are changing the manner in which we analyze and treat stomach related messes," he notes.

Telemedicine in Gastroenterology

The coronavirus epidemic hastened the adoption of telemedicine in healthcare. Dr. Lunkad discusses the advantages of telemedicine for gastrointestinal problems, including remote consultations and patient observation. "Telemedicine permits us to arrive at patients who might confront boundaries to in-person visits, guaranteeing congruity of care and convenient mediations," he says.

Patient Education and Empowerment

Dr. Lunkad has a strong desire to improve his comprehension of lessons. He acknowledges that empowered patients are those who are well-informed. Understanding your body and the elements that contribute to your overall welfare in terms of your stomach is the most important step in action and the executives. I encourage my patients to actively participate in their search for medical care and to seek clarification on some problems, he says.

Conclusion

Digestive disorders are intricate and diverse, but with the guidance of experts like Dr. Rupesh Lunkad, individuals can navigate these challenges with resilience. By promoting awareness, emphasizing prevention, and leveraging the latest advancements in gastroenterology, Dr. Lunkad continues to make a significant impact on digestive health in Pune and beyond. Remember, your digestive health matters—take the steps today for a healthier tomorrow.

[jashim6356]

Researchers say a few tests might have the option to distinguish the markers of delayed Coronavirus side effects from now on . This information joins an enormous development to acquire comprehension of long Coronavirus conditions

While there is no particular test to decide whether somebody is encountering long Coronavirus, another review distributed in Nature utilized blood tests to find new knowledge into what organic markers are related with this assortment of secretive circumstances announced by a great many Americans.

Analysts utilized AI to assist with breaking down safe markers and chemical levels in 273 grown-up members at Mount Sinai and Yale College and contrasted those and without long Coronavirus side effects no less than one year subsequent to having Coronavirus.

Long Coronavirus, characterized in this concentrate as tireless side effects over about a month and a half after contamination, was related with lower levels of a chemical called cortisol and had a few unmistakable contrasts in specific safe cells and provocative markers coursing in the blood.

These levels are distinguished through blood tests, however this isn't a blood test that explicitly tests for long Coronavirus.

MORE: Long Coronavirus assumed a part in a great many passings: CDC

"[These results] recommends a few potential instruments prompting long Coronavirus that may be manageable to treatment. It additionally may assist in recognizing patients with long Coronavirus," Dr. Alison Morris, division head of pneumonic, sensitivity, basic consideration and rest medication at the College of Pittsburgh Institute of Medication, told ABC News.

"I consider one the main discoveries of the paper is that it approves the side effects individuals have by tracking down natural contrasts among them and sound controls," Morris said.

"It is a really striking review," Dr. Shari Barnett Bresnahan, M.D., M.Sc., a Coronavirus specialist who was not engaged with the review and collaborator teacher of the division of pneumonic, basic consideration and rest medication at New York College Langone Wellbeing Framework, told ABC News. That's what brosnahan noticed "it's a restricted examination that they did, and I believe that there's even more work to be finished."

This study was finished on moderately couple of individuals, so scientists say more investigations are expected to extensively better figure out the meaning of these outcomes more. In any case, they say this study assists researchers with drawing one stage nearer to find out about lengthy Coronavirus. Assuming there are natural markers that are well defined for long Coronavirus, it could assist with affirming a determination or assist with focusing on medicines.

This examination joins an enormous development to acquire comprehension of long Coronavirus conditions and endeavors to offer types of assistance to those impacted, including endeavors by the Biden organization which as of late declared another Office of Long Coronavirus Exploration.

Long Coronavirus is a term used to describe signs, side effects and conditions that persevere for no less than about a month subsequent to getting contaminated with Coronavirus that might last a very long time to years, as per the functioning definition created by the U.S. Division of Wellbeing and Human Administrations.

These side effects can run in seriousness and effect numerous organ frameworks in the body. Normal grievances incorporate exhaustion, mind haze, rest issues, trouble breathing or windedness, tipsiness after standing, and stomach issues, as per the CDC.

In July 2021, long Coronavirus was perceived as a condition that could qualify as a handicap under the Americans with Inabilities Act if it "considerably restricts significant life exercises." Exploration that might be useful to specialists make a conclusion could be essential for those generally seriously influenced to get these vital administrations.

"I additionally trust that proceeding to have these examinations that show objective proof assist with approving individuals and understanding [of] their long Coronavirus," Bresnahan said. "Furthermore, assist us as a clinical local area with approving the infection of long Coronavirus somewhat more."

Dr. Jade A Coborn, M.D., M.P.H. is an authorized and rehearsing doctor and an individual from the ABC News Clinical Unit.

[davidboles]

Vitamin D Pinnacles and Pitfalls

In the Era of Covid — we learned Vitamin D can play a large role in helping keep us healthy and strong. Here’s a conversation I had with ChatGPT-4 to help explain the benefits, and side effects, of Vitamin D.

Does Vitamin D help fight Covid? If yes, explain the how and the why.

Yes, there has been considerable interest in the potential role of vitamin D in the prevention and treatment of COVID-19. While the data is not entirely conclusive, several studies suggest that vitamin D may have an influence on COVID-19 susceptibility and outcomes.

Here's how and why vitamin D might play a role:

1. **Immune System Modulation**: Vitamin D is known to modulate the immune system, enhancing innate immunity by promoting the production of antimicrobial peptides. It also modulates adaptive immunity by inhibiting the production of proinflammatory cytokines. This immune-balancing act may help the body to respond more effectively to infections, including the SARS-CoV-2 virus, responsible for COVID-19 (Cantorna et al., 2020).

2. **Reduction of Acute Respiratory Infections**: Vitamin D has been found to reduce the risk of acute respiratory infections, which is particularly relevant given that COVID-19 is primarily a respiratory illness. A meta-analysis of 25 randomized controlled trials (Martineau et al., 2017) demonstrated that vitamin D supplementation reduced the risk of acute respiratory tract infection, particularly among those who were vitamin D deficient.

3. **Link between Vitamin D Deficiency and Severity**: Some studies have observed that vitamin D deficiency is more common among individuals with severe COVID-19. A retrospective study (Meltzer et al., 2020) found that patients with vitamin D deficiency were more likely to test positive for COVID-19.

4. **Potential Impact on COVID-19 Mortality**: Research has shown a potential association between vitamin D levels and COVID-19 mortality. One study (Ilie et al., 2020) found that countries with lower vitamin D levels had higher mortality rates from COVID-19.

However, it is crucial to understand that while these observations are compelling, they do not definitively prove causation. Randomized controlled trials are the gold standard for determining causal relationships, and the data from such trials regarding vitamin D and COVID-19 is still inconclusive.

The relationship between vitamin D and COVID-19 is likely multifactorial and complex. As of my knowledge cut-off, there are ongoing clinical trials to further investigate this relationship.

Consultation with healthcare providers for personalized recommendations and recognizing that vitamin D is just one part of overall health and well-being is essential.

Sources:

- Cantorna MT, Snyder L, Lin YD, Yang L. Vitamin D and 1,25(OH)2D regulation of T cells. Nutrients. 2015;7(4):3011-3021. doi:10.3390/nu7043011

- Martineau AR, Jolliffe DA, Hooper RL, et al. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. BMJ. 2017;356:i6583. doi:10.1136/bmj.i6583

- Meltzer DO, Best TJ, Zhang H, Vokes T, Arora V, Solway J. Association of Vitamin D Status and Other Clinical Characteristics With COVID-19 Test Results. JAMA Netw Open. 2020;3(9):e2019722. doi:10.1001/jamanetworkopen.2020.19722

- Ilie PC, Stefanescu S, Smith L. The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality. Aging Clin Exp Res. 2020;32(7):1195-1198. doi:10.1007/s40520-020-01570-8

How many IU of vitamin D per day is safe to take?

Vitamin D, often called the "sunshine vitamin," is essential for maintaining healthy bones and teeth and has been implicated in supporting immune system function. It's interesting to note that while our bodies can synthesize vitamin D through exposure to sunlight, a significant number of individuals, especially those in less sunny climates, may require supplementation to meet their daily needs.

As per the U.S. National Institutes of Health (NIH), the recommended dietary allowance (RDA) for adults, including pregnant and lactating women, is 600 to 800 International Units (IU) per day. This is based on the assumption that a person gets virtually no sunlight.

However, the tolerable upper intake level (UL) for vitamin D, which is the maximum daily intake unlikely to cause adverse health effects, has been set at 4,000 IU per day for adults. It is important to mention that long-term intake above the UL can lead to vitamin D toxicity, which could manifest as hypercalcemia and its related symptoms, including nausea, vomiting, poor appetite, constipation, weakness, and weight loss. More severe cases can lead to confusion, disorientation, and damage to heart, blood vessels, and kidneys.

Individual needs for vitamin D can vary depending on factors such as age, sex, body weight, sunlight exposure, dietary intake, and overall health status. Therefore, for personalized advice, it would be prudent to consult with a healthcare provider who can offer guidance based on a comprehensive understanding of one's health history and current circumstances.

Sources:

1. Office of Dietary Supplements - Vitamin D. NIH. [Accessed 2023-07-22]. https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/

2. Holick MF. Vitamin D deficiency. N Engl J Med. 2007 Jul 19;357(3):266-81. doi: 10.1056/NEJMra070553. PMID: 17634462.

Is D3 any different?

Yes, Dave, vitamin D3 is indeed different from its counterpart, vitamin D2. Both are forms of vitamin D, but they originate from different sources and can exhibit varying effectiveness in the human body.

Vitamin D3, also known as cholecalciferol, is produced by our bodies when our skin is exposed to sunlight, specifically ultraviolet B (UVB) light. It's also found naturally in certain foods, including fatty fish (like salmon and mackerel), beef liver, cheese, and egg yolks. Furthermore, D3 is the form most commonly used in fortified foods and dietary supplements.

On the other hand, vitamin D2, or ergocalciferol, is primarily obtained through diet, and it's derived from fungal and plant sources. It is commonly used to fortify foods such as milk and orange juice.

From an effectiveness standpoint, multiple studies suggest that vitamin D3 is more efficacious at raising and maintaining adequate levels of the circulating form of vitamin D, known as 25-hydroxyvitamin D [25(OH)D], in the blood. This is an important consideration because 25(OH)D is the form measured in blood tests to assess and monitor vitamin D status in individuals.

Despite these differences, both forms can contribute to the maintenance of healthy bones and teeth, and support immune, brain, and nervous system health. They also play a role in regulating insulin levels and supporting lung function and cardiovascular health.

As a side note, whether you choose vitamin D2 or D3, taking them with a meal that contains fat can enhance absorption since vitamin D is a fat-soluble vitamin.

Sources:

1. Tripkovic L, Lambert H, Hart K, Smith CP, Bucca G, Penson S, Chope G, Hyppönen E, Berry J, Vieth R, Lanham-New S. Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic review and meta-analysis. Am J Clin Nutr. 2012 Jun;95(6):1357-64. doi: 10.3945/ajcn.111.031070. Epub 2012 May 2. PMID: 22552031; PMCID: PMC3349454.

2. Office of Dietary Supplements - Vitamin D. NIH. [Accessed 2023-07-22]. https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/

How many IU daily for D3?

The recommended dietary allowance (RDA) and upper intake levels (UL) for Vitamin D — whether in the form of D2 or D3 — remain the same. The U.S. National Institutes of Health (NIH) suggests an RDA of 600 to 800 International Units (IU) per day for adults, and a UL of 4,000 IU per day. These recommendations do not distinguish between vitamin D2 and D3.

That being said, it's worth noting that several research studies have indicated that vitamin D3 could be more effective than D2 in raising and maintaining adequate levels of 25-hydroxyvitamin D [25(OH)D] in the blood, the form of vitamin D typically measured to assess and monitor an individual's vitamin D status.

Sources:

1. Office of Dietary Supplements - Vitamin D. NIH. [Accessed 2023-07-22]. https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/

2. Tripkovic L, Lambert H, Hart K, et al. Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic review and meta-analysis. Am J Clin Nutr. 2012 Jun;95(6):1357-64. doi: 10.3945/ajcn.111.031070. Epub 2012 May 2. PMID: 22552031; PMCID: PMC3349454.

Is it possible to overdose on too much Vitamin D? If yes, what are the dangers and resolutions?

Yes, it is indeed possible to overdose on vitamin D, a condition known as hypervitaminosis D or vitamin D toxicity. This situation is generally rare and occurs as a result of chronic ingestion of excessive amounts of vitamin D, usually through supplementation, rather than from diet or sun exposure. Here's a breakdown of the dangers and resolutions:

### Dangers:

1. **Hypercalcemia**: One of the most significant risks of vitamin D toxicity is hypercalcemia, or elevated levels of calcium in the blood. Vitamin D enhances calcium absorption from the gut, and excessive vitamin D can lead to too much calcium being absorbed.

2. **Kidney Damage**: Chronic hypercalcemia can lead to the formation of calcium deposits in the kidneys, potentially causing permanent kidney damage.

3. **Cardiovascular Issues**: Excessive calcium in the blood can lead to vascular calcification and hypertension, impacting heart health.

4. **Bone Loss**: Paradoxically, too much vitamin D can also cause bone loss, as the increased blood calcium can stimulate resorption of calcium from the bones.

5. **Gastrointestinal Symptoms**: Nausea, vomiting, and poor appetite are common symptoms of vitamin D toxicity.

6. **Neurological Effects**: Confusion, disorientation, and other cognitive disturbances may occur.

### Resolutions:

1. **Immediate Cessation of Supplements**: If toxicity is suspected, immediate cessation of vitamin D supplements is usually required.

2. **Medical Assessment and Monitoring**: Evaluation by healthcare professionals to assess the severity and cause of the toxicity is essential. Blood tests to measure vitamin D and calcium levels may be conducted.

3. **Hydration and Medication**: Treatment may include hydration with intravenous fluids, especially in severe cases, and medications like diuretics to promote the excretion of calcium.

4. **Dietary Management**: Reducing dietary calcium intake may also be part of the treatment plan.

5. **Monitoring and Follow-up**: Regular follow-up to monitor calcium and vitamin D levels, as well as kidney function, may be necessary.

In summary, while vitamin D plays a critical role in numerous bodily functions, excessive amounts can lead to serious health problems. Vitamin D toxicity is largely preventable by adhering to recommended dietary allowances and consulting with healthcare providers before starting supplementation.

Sources:

- Office of Dietary Supplements - Vitamin D. NIH. [Accessed 2023-07-22]. https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/

- Holick MF. Vitamin D deficiency. N Engl J Med. 2007 Jul 19;357(3):266-81. doi: 10.1056/NEJMra070553. PMID: 17634462.

And so, as with everything, my friend, moderation is the key! Too much of any wonderful thing can turn out to be bad for you without modulation and responsibility. Enjoy your health! Work on making Vitamin D a good, and safe part, of your aging routine!