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breezingby · 5 months ago

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Potential Health Benefits

Honey has many potential health benefits, including: (here's just a Few)…

Anti-inflammatory

Honey contains an enzyme called catalase that can help relieve minor inflammation. It can be used topically to treat burns and wounds, and orally to treat coughs and sore throats.

Antibacterial and antiviral

Honey can help fight infections caused by bacteria, viruses, and fungi. It can also be used to treat acne by dabbing a small amount onto pimples to reduce swelling and fight bacteria.

Antioxidant

Honey contains antioxidants like phenolic acids and flavonoids, which may help improve cholesterol levels and decrease the risk of heart disease. Honey can also help prevent and treat degenerative diseases.

Studies suggest that honey might offer antidepressant, anticonvulsant and anti-anxiety benefits. In some studies, honey has been shown to help prevent memory disorders. Wound care. Topical use of medical-grade honey has been shown to promote wound healing, particularly in burns.

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Cinnamon has many potential health benefits, including:

Blood sugar

Cinnamon may help lower blood sugar levels, which can be beneficial for people with type 2 diabetes. It may also improve insulin sensitivity and glucose tolerance factor (GTf), which can help with weight loss.

In addition to being an antioxidant, anti-inflammatory, antidiabetic, antimicrobial, anticancer, lipid-lowering, and cardiovascular-disease-lowering compound, cinnamon has also been reported to have activities against neurological disorders, such as Parkinson's and Alzheimer's diseases.

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Ginger has many health benefits, including:

Digestion: Gingerol, a natural compound in ginger, can help with digestion, nausea, and vomiting from motion sickness, pregnancy, and cancer chemotherapy. It can also help with mild stomach upset.

Anti-inflammatory: Ginger contains over 400 natural compounds, some of which are anti-inflammatory. It can help with bloating, gas, and reducing inflammation.

Pain relief: Ginger can help with osteoarthritis pain, menstrual cramps, and sore muscles.

Blood sugar: Ginger can help improve blood sugar regulation and lower blood sugar.

Heart health: Ginger can help lower blood pressure and cholesterol, which can help prevent heart disease. It can also improve circulation and promote the breakdown of fats in the bloodstream.

Immune system: Ginger can help strengthen the immune system and fight germs.

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Turmeric ~ In addition to these conditions, research studies have shown some possible benefits of turmeric for:

Inflammation

Degenerative eye conditions

Metabolic syndrome

Arthritis

Hyperlipidemia (cholesterol in the blood)

Anxiety

Muscle soreness after exercise

Kidney health

In India, it was traditionally used for disorders of the skin, upper respiratory tract, joints, and digestive system. Today, turmeric is promoted as a dietary supplement for a variety of conditions, including arthritis, digestive disorders, respiratory infections, allergies, liver disease, depression, and many others.

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Chili peppers contain many compounds that may have health benefits, including:

Capsaicin The chemical that gives chili peppers their heat, capsaicin may help with:

Pain relief: Chili peppers can help with headaches, migraines, and joint pain. You can apply chili peppers directly to the skin to reduce the amount of a chemical that sends pain signals to the brain.

Metabolism: Capsaicin can increase your metabolic rate, which can help you burn more calories and eat fewer unhealthy foods. Some studies have also shown that capsaicin can reduce appetite and increase fat burning, which may help with weight loss.

Inflammation: Capsaicin is one of the most studied natural ingredients for its anti-inflammatory properties.

Digestion: Capsaicin can help clear phlegm and congestion, and may promote a healthy gut microbiome, which is important for a healthy immune system.

Vitamin A and vitamin C: Chili peppers are a great source of both vitamins, which can help boost your immune system and support eye health. Vitamin C can also help your body absorb iron and promote healthy skin.

Carotenoids: Chili peppers contain carotenoids, which may help protect against cancer. Some research suggests that capsaicin may also contribute to cancer cell death.

Keep in Mind

Take charge of your health—talk with your health care providers about any complementary health approaches you use. Together, you can make shared, well-informed decisions.

Using Dietary Supplements Wisely

Know the Science: How Medications and Supplements Can Interact

Know the Science: How To Make Sense of a Scientific Journal Article

#Health Benefits #Do Your Research

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dhakshin-ayurveda · 1 month ago

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Curcuma Longa Rhizome Powder: The Golden Spice with Remarkable Health Benefits

Introduction

Curcuma longa is an important plant of the ginger family that is commonly known as turmeric. When dried and ground into powder, the rhizome has been used as spice, dye and has medicinal value for many centuries. commonly referred to as the ‘Golden spice,’ turmeric contains several pharmacological agents, [curcuminoids], with curcumin being the most researched for its antioxidant effect, anti-inflammation, antimicrobial action, & anticancer properties, etc. This blog looks at the chemical constitution, therapeutic properties, and the source, which backs up the use of turmeric rhizome powder from the conventional and contemporary medication.

1.Historical and Traditional Uses

Ayurveda and Traditional Medicine

Haridra is the term used in Ayurvedic science for turmeric, and it is one of the most useful spices. It is taken to maintain the doshas; Vata, Pitta and Kapha and in managing conditions such as skin diseases, respiratory complaints and gastrointestinal complaints. Turmeric is also utilized in non Surgical formulations such as Haridra Khand in allergies, Kumudakshi taila for skin.

Cultural Significance

In India turmeric is associated with purity and wealth, and is used in religious rites, in weddings and other celebrations. It has also been used for wound and infection treatments traditionally, due to the presence of antiseptic characteristics in it.

2.Chemical Composition of Curcuma Longa Rhizome Powder

The therapeutic potential of turmeric lies in its diverse phytochemical composition, including:

Curcuminoids (2–5%) Curcumin (C₂₁H₂₀O₆): The primary bioactive compound responsible for turmeric’s bright yellow color and potent health benefits.

Demethoxycurcumin and bisdemethoxycurcumin: Curcuminoids with complementary effects to curcumin.

2. Volatile Oils (4–14%): Includes turmerone, zingiberene, and ar-turmerone, which contribute to its anti-inflammatory and antimicrobial properties .

Polysaccharides Known for their immunomodulatory and anti-ulcer effects.

Proteins and Resins Play a role in turmeric’s therapeutic effects on digestion and skin health.

3.Health Benefits of Curcuma Longa Rhizome Powder

a)Potent Anti-inflammatory Effects

Inflammation is a major cause of diseases including arthritis, diabetes and cardiovascular diseases and turmeric is used therapeutically to reduce chronic inflammation.

Mechanism of Action: Curcumin also suppresses the expression of enzymes involved in COX-2 and LOX and the NF-κB signaling pathway which is involved in TNF-α and IL-6 cytokines .

Evidence: Research indicates that administration of turmeric modestly decreases pain and inflammation in patients suffering from osteoarthritis similar to NSAIDs but less side effects.

b) It is an Efficient AntiOxidant Substrate chronic inflammation, a key contributor to diseases like arthritis, diabetes, and cardiovascular conditions

b)Powerful Antioxidant Properties

Curcumin is a strong antioxidant, protecting cells from oxidative stress caused by free radicals.

Mechanism: It neutralizes reactive oxygen species (ROS) and enhances the activity of endogenous antioxidant enzymes like superoxide dismutase (SOD) and catalase .

•Evidence: Research confirms that turmeric supplementation reduces markers of oxidative stress in conditions such as diabetes and metabolic syndrome .

c)Digestive Health and Liver Protection

Turmeric strengthens the intestinal lining and has antioxidants that neutralize toxic substances and reduce liver oxidative stress.

Bile Production: It aids in bile production and therefore prevents cases of bloating and indigestion in most people who take it.

Hepatoprotective Effects: Curcumin blocks the inflammation of hepatocytes and free radicals that causes liver damage. Research writes it down in ways such as in non-alcoholic fatty liver disease (NAFLD)

d)Cardiovascular Benefits

Recent studies also show that curcumin helps support cardiovascular health by maintaining lipid levels and decreasing inflammation.

•Cholesterol Regulation: To date, clinical studies highlight that turmeric decreases levels of LDL cholesterol and triglycerides and at the same time increases levels of HDL cholesterol.

•Blood Pressure Control: It’s an arterial dilator associated with nitric oxide that enhances the ability of arteries to dilate hence enhancing blood flow

e) Skin and Wound Healing

It has been used in the past in treating various skin disorders including wound, eczema and psoriasis.

Antimicrobial Action: It also has abilities of combating infections since the growth of bacteria, fungi and virus is prevented by curcumin.

SkinRegeneration: It has an anti-inflammatory effect and stimulates the production of collagen therefore enhancing speedy healing and little scarring .

f) Immune System Support

Turmeric increases the function of the immune cells by regulating its activity.

Immunomodulatory Effects: It increases the activity of macrophages T- cells, and Natural killer (NK)cells Fig. 1.

AntiviralProperties: Research also shows that curcumin can delay the viral replication in such virus infections as influenza and hepatitis.

g) Anti-cancer Potential

Curcumin is investigated for its potential to prevent as well as cure different types of cancer rampantly.

Induction of Apoptosis: It targets the cancer cells for apoptosis without affecting non cancerous cells .

Angiogenesis Inhibition: Tumour growth requires formation of new blood vessels, which this drug is able to inhibit, reducing cancer development .

4. Mechanisms of Action

Mechanisms of Action Enzyme Inhibition: It suppresses some synthesis of inflammatory mediators such as COX-2 and LOX which lower inflammation.

Gene Regulation: Regulates genes with inflammatory response, oxidation, and cell survival including knocking down NF-κB and MAPK.

Antioxidant Defense: Increases the body’s natural antioxidant level as well as neutralizing free radicals.

Cellular Protection: Antioxidant, shields DNA and cell membranes to reverse effect of chronic diseases

5. Modern Applications of Curcuma Longa Rhizome Powder

Nutraceuticals: It helps in mixtures used in supplements for treating joint aches, boosting immunity and general body health.

Functional Foods: Consumed as a wellness supplement in golden milk, teas, and energy bars.

Cosmetics: Used together with skincare products for it also has anti-inflammatory and skin illuminating properties.

Pharmaceuticals: Also incorporated in preparations for control of inflammatory and metabolic diseases

6.Safety and Recommended Dosage

Safety Profile

However, the common yellow spice, turmeric, is safe for consumption. There are always side effects of most supplements especially when taken in large quantities and this may include a rise in heart rate and mild gastric upsets.

Recommended Dosage

For general wellness: 500–2,000 mg of curcumin daily, standardized to 95% curcuminoids.

Always consult a healthcare provider before starting supplementation, especially if on medication or pregnant.

Conclusion

Curcuma longa rhizome powder is the golden spice of India containing curcuminoids and a variety of bioactive compounds that are recommended in traditional medicine practice and supported by scientific evidence. With its cleansing and anti-inflammatory and antioxidant effects, digestive health benefits through demonstration of boost to immunity as well as chronic disease relief, turmeric still holds its status as a natural remedy. From cooking to beverages and supplements to skincare products, turmeric is still pushing its curcumin cure for a healthier you.

#ayurveda #dhakshin #best ayurveda in hyderabad #ayurveda in hyderabad #ayurveda and wellness

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ayushaktiayurveda · 4 months ago

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Discover 17 Powerful Health Benefits of Wheatgrass

Wheatgrass, derived from the young shoots of the common wheat plant (Triticum aestivum), is a highly nutritious supplement available in both juice and powder form. Unlike wheat malt, wheatgrass is often consumed fresh or freeze-dried to preserve its full range of nutrients. Additionally, wheatgrass is allowed to grow longer than wheat malt, maximizing its health-boosting properties.

17 Potential Health Benefits of Wheatgrass Juice Wheatgrass juice, when recommended by a healthcare professional, can be incorporated into holistic treatments and may support the management of chronic ailments. Known for its rich chlorophyll content, wheatgrass juice is often considered a safer alternative for detoxification and immune support. Below are some of the key benefits:

1. Boosts Immune System: Packed with amino acids, enzymes, and antioxidants, wheatgrass juice helps shield the body from pollutants and harmful carcinogens.

2. Nutrient-Rich and Full of Antioxidants: Loaded with essential vitamins and minerals, wheatgrass juice aids in detoxification and helps combat oxidative stress caused by free radicals.

3. Enhances Hair Health: The catalase enzyme and antioxidants in wheatgrass juice may slow down hair greying and improve shine and overall hair quality.

Read More: https://www.ayushakti.com/discover-17-powerful-health-benefits-of-wheatgrass/

#ayurveda #wheatgrass #healthcare

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openintegrative · 5 months ago

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Boron is a small but mighty mineral with big health benefits! 🧠

Boron is a trace mineral with significant health benefits.

It supports brain function, bone health, and hormonal balance.

Understanding boron’s role can improve overall wellbeing.

The Role of Boron in the Body

Energy

One of boron’s key functions is to help retain magnesium within cells. Magnesium is essential for many biological processes, but its most crucial role involves its conversion into magnesium-adenosine triphosphate (Mg-ATP).

Mg-ATP is the primary molecule that stores and transfers energy within cells, fueling various cellular activities and processes.

In essence, boron helps ensure that magnesium is available where it’s needed most, enabling the production of Mg-ATP and thereby supporting the energy needs of the cell.

This process is vital for maintaining cellular energy levels and overall metabolic health.

Brain Function

Boron significantly impacts cognitive function and mental clarity. Adequate boron intake can improve memory, focus, and mental agility.

Memory Enhancement: Boron supports the brain’s ability to process and retain information. Studies have shown that individuals with sufficient boron levels perform better in memory and cognitive tasks.

Mental Clarity: Boron helps maintain clear thinking and reduces mental fatigue. It supports neurotransmitter function, which is vital for quick and effective communication between brain cells.

Bone Health

Boron is important for maintaining strong and healthy bones. It improves magnesium absorption and balances magnesium and calcium levels, essential for bone density and strength.

Calcium Absorption: Boron helps the body retain calcium, reducing the risk of bone loss and osteoporosis.

Hormonal Balance

Boron plays a role in regulating hormones, impacting various aspects of health, including reproductive health and energy levels.

Estrogen and Testosterone Regulation: Boron helps maintain balanced levels of estrogen and testosterone, which are crucial for both men and women.

This balance supports reproductive health, muscle mass, and energy levels.

Menopausal Symptoms: Boron may help alleviate symptoms of menopause by supporting hormonal balance.

Antioxidant and Antifungal Properties

Boron raises levels of antioxidant enzymes such as superoxide dismutase (SOD), catalase, and glutathione.

These enzymes thwart the pro-oxidant action of excess, unbound iron in the body, lowering oxidative stress in the liver and other organs.

This process reduces the drain on copper, an essential nutrient.

Boron also exhibits antifungal properties and has been found to inhibit Candida albicans, a common fungal pathogen.

Sources of Boron

Dietary Sources

Boron is found in various foods, making it relatively easy to include in a balanced diet.

Vegetables: Leafy greens, carrots, and legumes contain significant amounts of boron.

Nuts and Seeds: Almonds, walnuts, and sunflower seeds are excellent sources of boron.

Fruits: Apples, pears, grapes, and avocados are rich in boron.

Whole Grains: Foods like quinoa, oats, and brown rice contribute to boron intake.

Supplementation

Plant-based sources of boron may contain high carbohydrates, oxalates, or other undesirable chemicals. For those who may not get enough boron from their diet, supplements are available.

Consulting with a healthcare provider before starting any supplementation ensures it meets individual health needs.

Potential Risks and Considerations

While boron is beneficial, it is essential to consume it in appropriate amounts. Excessive intake can lead to toxicity and adverse health effects.

Recommended Dosage: The recommended daily intake of boron is a minimum of 3 mg per day, which has been shown to be beneficial for human health. Higher doses should only be taken under medical supervision.

Possible Side Effects: Overconsumption of boron can cause nausea, vomiting, and other digestive issues. Long-term high intake can lead to more severe health problems.

Conclusion

Boron is a vital trace mineral with numerous health benefits, particularly for brain function, bone health, and hormonal balance. Including boron-rich foods in your diet or considering supplementation, under professional guidance, can enhance overall wellbeing and support long-term health.

FAQs

What foods are high in boron? Foods like apples, pears, grapes, avocados, leafy greens, carrots, almonds, walnuts, and whole grains are rich in boron.

How does boron improve brain function? Boron supports cognitive functions like memory, focus, and mental clarity by aiding neurotransmitter function and reducing mental fatigue.

Can boron help with bone health? Yes, boron improves the body’s ability to absorb calcium and magnesium, which are essential for maintaining strong and healthy bones.

Is boron supplementation safe? Boron supplements are generally safe when taken within the recommended dosage. It’s important to consult with a healthcare provider before starting supplementation.

How does boron affect hormonal balance? Boron helps regulate estrogen and testosterone levels, supporting reproductive health and alleviating symptoms of hormonal imbalances.

Research

Armstrong T. A., Spears J. W., Crenshaw T. D., Nielsen F. H., Boron supplementation of a semipurified diet for weanling pigs improves feed efficiency and bone strength characteristics and alters plasma lipid metabolites, J. Nutr., 139, 2575-2581, 2000.

Balci Yuce H., Toker H., Goze F., The histopathological and morphometric investigation of the effects of systemically administered boric acid on alveolar bone loss in ligature-induced periodontitis in diabetic rats, Acta Odontologica Scandinavica 72, 729-736, 2014.

Bolt, H.M., Başaran, N. and Duydu, Y., 2020. Effects of boron compounds on human reproduction. Archives of Toxicology, [online] 94(3), pp.717–724. https://doi.org/10.1007/s00204-020-02700-x.

Dinca, L. and Scorei, R., 2013. Boron in human nutrition and its regulations use. J Nutr Ther, 2(1), pp.22-29.

Fort D. J., Rogers R. L., McLaughlin D. W., Sellers C. M., Schlekat C. L., Impact of boron deficiency on Xenopus laevis, A summary of biological effects and potential biochemical roles, Biol. Trace Elem. Res., 90, 117-142, 2002.

Gorustovich A. A., Steimetz T., Nielsen F. H., Guglielmotti M. B., Histomorphometric study of alveolar bone healing in rats fed a boron-deficient diet, Anatomical Record (Hoboken), 291, 441-447, 2008.

Gorustovich A. A., Steimetz T., Nielsen F. H., Guglielmotti M. B., A histomorphometric study of alveolar bone modeling and remodeling in mice fed a boron-deficient diet, Archives of Oral Biology, 53,677-682, 2008.

Hakki S. S., Bozkurt B. S., Hakki E. E., Boron regulates mineralized tissue-associated proteins in osteoblasts (MC3T3-E1), J. Trace Elem. Med. Biol., 24, 243-250, 2010.

Hakki S. S., Malkoc S., Dundar N., Kayis S.A., Hakki E. E., Hamurcu M., Baspinar N., Basoglu A., Nielsen F. H., Götz W., Dietary boron does not affect tooth strength, micro-hardness, and density, but affects tooth mineral composition and alveolar bone mineral density in rabbits fed a high-energy diet, J. Trace Elem. Med. Biol., 29, 208-215, 2015.

Hosmane, N.S., 2011. Boron science. New technologies and applications.

Hunt C. D., Herbel J. L., Idso J. P., Dietary boron modifies the effects of vitamin D3 nutriture on indices of energy substrate utilization and mineral metabolism in the chick, J. Bone Miner. Res., 9, 171-181, 1994.

Hunt C. D., Nielsen F. H., Interaction between boron and cholecalciferol in the chick, Trace Elements Metabolism in Man and Animals, TENA-4, Australian Academy of Science, Canberra, Australia, pp. 597-600, 1981.

Hunt C. D., Dietary boron: Evidence for essentiality and homeostatic control in humans and animals, Advances in Plant and Animal Boron Nutrition, Springer, Dordrecht, The Netherlands, pp. 251-267, 2007.

Ince, S., Filazi, A., & Yurdakok-Dikmen, B. 2022. Boron. Reproductive and Developmental Toxicology (Third Edition), 531-546. https://doi.org/10.1016/B978-0-323-89773-0.00028-X

Khaliq, H., Juming, Z. and Ke-Mei, P., 2018. The Physiological Role of Boron on Health. Biological Trace Element Research, [online] 186(1), pp.31–51. https://doi.org/10.1007/s12011-018-1284-3.

Kot, F.S., 2008. Boron sources, speciation and its potential impact on health. Reviews in Environmental Science and Bio/Technology, [online] 8(1), pp.3–28. https://doi.org/10.1007/s11157-008-9140-0.

Majafabadi B. M., Abnosi M. H., Boron induces early matrix mineralization via calcium deposition and elevation of alkaline phosphatase activity in differentiated rat bone marrow mesenchymal stem cells, Cell Journal (Yakhteh), 18, 62-73, 2016.

Nielsen, F. H., Dietary fat composition modifies the effect of boron on bone characteristics and plasma lipids in rats, BioFactors, 20, 161-171, 2004.

Nielsen, F. H., 2014. Update on human health effects of boron. Journal of Trace Elements in Medicine and Biology, 28(4), 383-387. https://doi.org/10.1016/j.jtemb.2014.06.023

Nielsen, F. H., 2020. Manganese, molybdenum, boron, silicon, and other trace elements. In Present knowledge in nutrition (pp. 485-500). Academic Press.

Nielsen, F. H., and Eckhert, C.D., 2020. Boron. Advances in Nutrition, [online] 11(2), pp.461–462. https://doi.org/10.1093/advances/nmz110.

Nielsen, F. H., and Meacham, S.L., 2011. Growing Evidence for Human Health Benefits of Boron. Journal of Evidence-Based Complementary & Alternative Medicine, [online] 16(3), pp.169–180. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712861/

Pizzorno, L., 2015. Nothing boring about boron. Integrative Medicine: A Clinician's Journal, 14(4), p.35. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712861/

Rowe R. I., Eckhert C. D., Boron is required for zebrafish embryogenesis, J. Exp. Biol., 12, 221-233, 1999.

Sağlam M., Hatipoğlu M., Köseoğlu S., Esen H. H., Kelebek S., Boric acid inhibits alveolar bone loss in rats by affecting RANKL and osteoprotegerin expression, Journal of Periodontal Research, 49, 472-479, 2014.

Sutherland, B., Woodhouse, L. R., Strong, P., & King, J. C. (1999). Boron balance in humans. The Journal of Trace Elements in Experimental Medicine, 12(3), 271-284. https://doi.org/10.1002/(SICI)1520-670X(1999)12:3<271::AID-JTRA10>3.0.CO;2-B

Taşh P. N., Doğan A., Demirci S., Şahin F., Boron enhances odontogenic and osteogenic differentiation of human tooth germ stem cells (hTGSCs) in vitro, Biol. Trace Elem. Res., 153, 419-427, 2013.

Ying X., Cheng S., Wang W., Lin Z., Chen Q., Zhang W., Kou D., Shen Y., Cheng X., Rompis F.A., Peng L., Lu C.Z., Effect of boron on osteogenic differentiation of human bone marrow stromal cells, Biol. Trace Elem. Res., 144, 306-315, 2011.

#minerals #bone health #brain function #hormone balance

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thesongthesoulsings · 1 year ago

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Breastfeeding Exclusively Reduces Autism Risk Significantly

August 22, 2018

The idea of ‘preventing’ or ‘avoiding’ Autism gets parents all up in arms. It’s an uncomfortable topic, and many parents feel guilt or shame for their child’s condition. Many parents argue that Autism is primarily genetic and unavoidable, case closed. If you bring up vaccines, good luck.

However, way back in 2006, we knew that breastfeeding exclusively for more than 6 months reduces your child’s risk of Autism by 2.5 times. The study found that infant formula without DHA increased one’s odds of ASD by 4.4 times over exclusive breastfeeding. When looking at regression only, it bumped up to more than 12 times the risk!

A 2017 study titled “Impact of Infant Feeding Methods on the Development of Autism Spectrum Disorder” found that increasing the duration of breastfeeding resulted in a decrease in prevalence of ASD. For infants breastfed longer than 12 months, they were 6.67 times less likely to be diagnosed with autism.

More recently, a February 2020 meta analysis found exactly what we assumed: there is a dose-response relationship to breastfeeding and protection from Autism. The authors write:

We found a 58 % decrease in the risk of autism spectrum disorder with ever breastfeeding and a 76 % decrease in the risk with exclusive breastfeeding. According to our dose-response meta-analysis, breastfeeding for 6 months was associated with a 54 % reduction in the risk. In the conventional meta-analysis, breastfeeding for 12–24 months was associated with the most significant reduction in the risk of autism spectrum disorder. Our results highlight the importance of breastfeeding to decrease the risk of autism spectrum disorder.

For the sake of our kids, we have to shake the genetic narrative

The idea that breastfeeding exclusively, no formula supplementation, significantly reduces your child’s risk for autism honestly shatters the idea that autism is solely caused in the womb.

It destroys the narrative that autism is unavoidable. Which is a good thing. We don’t want to hide information or reframe a condition so that we don’t hurt or offend parents. This is about the kids. It’s not about us.

Every scientific study I come across acknowledges the contribution of the environment, specifically environmental toxins in the formation of autism. Why can’t we use this information to educate and support breastfeeding mothers?

Breastmilk contains antioxidants like vitamin C and E and enzymes, including superoxide dismutase, catalase, and glutathione peroxidase. These are known to protect against the potentially-harmful effects of oxidative stress.

Oxidative stress is a significant clinical finding in Autism—alterations in the activities of antioxidant enzymes such as superoxide dismutase, glutathione peroxidase, and catalase, altered glutathione levels and homocysteine/methionine metabolism, increased inflammation, excitotoxicity, as well as mitochondrial and immune dysfunction are found in autistic brains.

If babies who have genetic markers for autism are formula fed, given Tylenol, and given vaccines, you are sealing the deal. Breastfeeding exclusively may prevent or lessen the damage from inflammation and oxidative stress, and help with rewiring the brain.

We know Tylenol decreases glutathione. We know breastmilk replenishes the body’s antioxidants necessary to repair cells and prevent damage. Infant formula is synthetic, GMO, contains pesticides, aluminum, fluoride and adds more to oxidative stress.

We know that vaccines can only add to oxidative stress and inflammation. Lessen the risk if you can. Breast milk is the only biologically appropriate food for an infants rapidly growing brain.

Links:

Association of breastfeeding status with risk of autism spectrum disorder: A systematic review, dose-response analysis and meta-analysis

Breastfeeding, infant formula supplementation, and Autistic Disorder: the results of a parent survey

Association between breastfeeding duration and cognitive development, autistic traits and ADHD symptoms: a multicenter study in Spain

Long-term neurodevelopmental benefits of breastfeeding

Breast Milk Protects Against Gastrointestinal Symptoms in Infants at High Risk for Autism During Early Development

Maternal and birth risk factors for children screening positive for autism spectrum disorders on M-CHAT-R

The role of oxidative stress, inflammation and acetaminophen exposure from birth to early childhood in the induction of autism

#breastfeeding #autism #prevention #health #maternity #childhood #nutrition #studies

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xiaozb · 1 year ago

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Anti aging, antioxidant first!

First, here comes a comprehensive strategy for # antioxidant protection in one step!

What is # oxidation reaction?

In the process of human metabolism, when there is an imbalance between oxidation and antioxidant activity (tendency towards oxidation) in the body, the negative effects caused by excessive reactive oxygen species (including oxygen free radicals) are called oxidative stress reactions.

Antioxidation mainly involves resisting # free radicals.

Protect cells from free radicals and delay cell aging.

The earlier you do antioxidant, the slower you age!

How do free radicals arise?

1、 Endogenous

Free radicals are produced during the metabolic process of the human body

As one ages, their ability to clear free radicals decreases

The inflammatory response of cells can lead to the production of free radicals

2、 Exogenous

Environmental factors such as ultraviolet radiation, external pollution, and radiation exposure can lead to the production of free radicals

Bad lifestyle habits, such as staying up late, eating irregularly, etc

Antioxidant mechanism: preventing the clearance of free radicals

1、 Enzymatic antioxidants

Mainly including:

Superoxide dismutase (SOD), catalase (CAT)

Glutathione Peroxidase (GSH-Px)

Glutathione thiol transferase (GST).

2、 Non enzymatic antioxidants (also known as small molecule antioxidants)

Mainly including vitamin C, vitamin E, carotenoids β Carotenoids, glutathione, melatonin, and selenium.

How to Antioxidant - Daily Life Chapter

1. Do more aerobic exercise to improve physical fitness and self resist free radicals in the body

2. Adhere to sun protection: hard sun protection (umbrella, sunscreen, etc.)+soft sun protection (sunscreen)

3. Avoid smoking and drinking, and have a regular lifestyle

4. Maintain a pleasant mood and reduce negative emotions and life stress

5. Reduce radiation, stay away from environmental pollution such as oil fumes

6. Eat less fried and oily foods. It is recommended to consume at least 13 types of food daily and supplement natural antioxidants such as flavonoids, phenolic acids, and astragalus through diet

7. Use antioxidant skincare products and pay attention to daily cleaning

How to Antioxidant - Chapter on Antioxidant Components

Sources of antioxidant components

1. The human body can synthesize some important antioxidant components, such as glutathione, SOD (superoxide dismutase), coenzyme Q10, etc. These antioxidant components are transported to various parts of the body with the blood for the needs of cellular tissues.

2. Use antioxidants. The essence of antioxidants is "reducing agents". When free radicals enter the human body and damage cells, reducing agents will step forward and neutralize them into neutral substances, preventing skin cells from being damaged.

3. External antioxidant ingredients can also help the skin fight against free radicals and maintain a youthful state of skin health.

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cheyannemallas · 1 year ago

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What are Antioxidants and why are they important?

The Significance of Antioxidants in Human Health: An Overview and Importance

Antioxidants have gained considerable attention in recent years due to their potential health benefits says Cheyanne Mallas. These compounds play a crucial role in maintaining cellular homeostasis by counteracting the damaging effects of free radicals. This article aims to provide an authoritative overview of antioxidants, their mechanisms of action, and their importance for human health.

Body:

1. Definition and Types of Antioxidants:

Antioxidants are molecules that can neutralize free radicals, unstable molecules with unpaired electrons that can cause oxidative damage to cells. There are two primary types of antioxidants:

a. Endogenous Antioxidants: These are naturally produced by the body, including enzymes such as superoxide dismutase, catalase, and glutathione peroxidase.

b. Exogenous Antioxidants: These are obtained through diet or supplementation and include vitamins (E, C, A), minerals (selenium, zinc), and phytochemicals (polyphenols, flavonoids).

2. Mechanisms of Antioxidant Action:

Antioxidants function through various mechanisms to neutralize free radicals and prevent oxidative stress:

a. Free Radical Scavenging: Antioxidants can donate an electron to stabilize free radicals, preventing them from causing damage to cellular components.

b. Chelation: Certain antioxidants, such as vitamin E, selenium, and zinc, can bind to metal ions, reducing their ability to generate reactive oxygen species.

c. Enzymatic Activity: Endogenous antioxidants like superoxide dismutase and catalase catalyze reactions that convert harmful free radicals into less reactive molecules.

3. Importance of Antioxidants for Human Health:

The importance of antioxidants for human health is multifaceted, with several key implications:

a. Neutralizing Free Radicals: Free radicals are constantly produced in the body as a result of various metabolic processes, environmental pollutants, and lifestyle factors. Antioxidants help maintain the delicate balance between free radicals and antioxidants, preventing excessive oxidative damage.

b. Reducing Chronic Disease Risk: Oxidative stress is associated with the development of various chronic diseases, including cardiovascular diseases, cancer, neurodegenerative disorders, and age-related macular degeneration. Antioxidants help mitigate oxidative stress, thus reducing the risk of these diseases.

c. Enhancing Immune Function: Antioxidants play a crucial role in supporting immune system function by protecting immune cells from oxidative damage and enhancing their defense mechanisms against pathogens.

d. Anti-inflammatory Effects: Oxidative stress contributes to chronic inflammation, which is a common underlying factor in several diseases. Antioxidants can reduce inflammation by neutralizing free radicals and modulating inflammatory signaling pathways.

In conclusion, Antioxidants are essential for maintaining cellular health and preventing oxidative damage says Cheyanne Mallas. Their ability to neutralize free radicals, reduce chronic disease risk, enhance immune function, and mitigate inflammation underscores their importance for human health. Incorporating a balanced diet rich in antioxidant-rich foods and considering antioxidant supplementation under specific circumstances can help optimize antioxidant status and promote overall well-being. Further research is needed to explore the optimal dosage, sources, and interactions of antioxidants for personalized health benefits.

#Cheyanne Mallas #Cheyanne Mallas PA #Cheyanne Mallas California #Cheyanne Mallas Los Angeles

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getbudslegalize · 2 years ago

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What Are Cannabis Flavonoids? Health Benefits and Uses

What Are Cannabis Flavonoids? Medical Benefits and Uses

Cannabis flavonoids are a group of natural compounds that give cannabis plants their distinctive colors, aromas, and flavors. They are also responsible for some of the beneficial effects of cannabis, such as anti-inflammatory, antioxidant, and neuroprotective effects.

What Do Flavonoids Do?

Flavonoids have multiple roles in cannabis plants. They protect the plants from UV radiation, pests, pathogens, and environmental stress. They also modulate the production and activity of cannabinoids and terpenes, the main active compounds in cannabis. Flavonoids may also have beneficial effects on human health. They may interact with the endocannabinoid-system, a network of receptors and molecules that regulate various physiological processes such as pain, mood, appetite, memory, and inflammation. They may also modulate the activity of enzymes and transporters that affect the metabolism and bioavailability of cannabinoids and other drugs.

How Do Flavonoids Work In The Body?

Flavonoids work in different ways depending on their structure, concentration, and target. - Some flavonoids may bind to cannabinoid receptors (CB1 and CB2) or other receptors (such as PPARs, TRPVs, and GPR55) and either activate or inhibit them. - Some flavonoids may inhibit or induce enzymes (such as CYPs, FAAH, and COX) that break down or synthesize cannabinoids and other compounds. - Some flavonoids may affect the expression or function of transporters (such as ABCs, SLCs, and GLUTs) that move cannabinoids and other molecules across cell membranes. The effects of flavonoids may also depend on their interactions with other compounds in cannabis or in the body. For example, some flavonoids may enhance or reduce the effects of cannabinoids by modulating their absorption, distribution, metabolism, or excretion. Some flavonoids may also act synergistically or antagonistically with other flavonoids or terpenes to produce entourage effects.

What Are The Benefits and Uses of Flavonoids?

Flavonoids have a range of benefits for different health conditions and wellness goals. Some of the potential health benefits are: - Antioxidant: Flavonoids can scavenge free radicals and protect cells from oxidative damage, which is associated with aging and many diseases. They can also modulate the expression and activity of antioxidant enzymes, such as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx). - Anti-inflammatory: Flavonoids can inhibit the production and release of pro-inflammatory mediators, such as cytokines, prostaglandins, and leukotrienes. They can also suppress the activation of inflammatory pathways, such as nuclear factor-kappa B (NF-κB), mitogen-activated protein kinases (MAPKs), and cyclooxygenases (COXs). - Anti-cancer: Flavonoids can induce apoptosis (programmed cell death) and autophagy (self-digestion) of cancer cells, as well as inhibit their proliferation, migration, invasion, and angiogenesis (blood vessel formation). They can also modulate the expression and activity of various oncogenes (cancer-promoting genes) and tumor suppressor genes (cancer-inhibiting genes). - Neuroprotective: Flavonoids can protect neurons from various insults, such as ischemia (lack of blood supply), excitotoxicity (overstimulation by glutamate), neuroinflammation, and neurodegeneration. They can also enhance neurogenesis (new neuron formation), synaptic plasticity (neural adaptation), and cognitive function. - Other effects: Flavonoids may also have anti-diabetic, anti-obesity, anti-allergic, anti-microbial, anti-viral, anti-fungal, anti-parasitic, anti-ulcer, hepatoprotective (liver-protecting), cardioprotective (heart-protecting), and bone-protective effects. Flavonoids may be used as natural supplements or adjuvants for various health conditions, such as chronic pain, inflammation, cancer, neurodegenerative diseases, metabolic disorders, allergic reactions, infections, ulcers, liver diseases, cardiovascular diseases, and osteoporosis. However, more clinical trials are needed to confirm the safety and efficacy of cannabis flavonoids in humans.

How Do Flavonoids Interact With Cannabinoids and Terpenes?

Flavonoids may enhance the effects of cannabinoids and terpenes through a phenomenon called the entourage effect. This means that the combination of different compounds in cannabis may produce synergistic effects that are greater than the sum of their individual effects. For example, some flavonoids may increase the bioavailability of cannabinoids by inhibiting their metabolism or facilitating their absorption. Some flavonoids may also modulate the activity of cannabinoid receptors or other receptors that cannabinoids interact with. Some terpenes may also enhance the absorption or penetration of flavonoids into cells or tissues. The entourage effect may explain why whole-plant cannabis extracts or products may have more benefits than isolated cannabinoids or synthetic versions. However, more research is needed to understand the exact mechanisms and outcomes of the interactions between flavonoids, cannabinoids, and terpenes.

How Many Flavonoids Are in Cannabis?

There are over 10,000 known flavonoids in nature, but those found in cannabis fall into six main subcategories: 1. Chalcones: These flavonoids are brown shade pigments that are found in many plants, such as apples, strawberries, and tomatoes. Chalcones have antioxidant, anti-inflammatory, anti-fungal, and anti-cancer effects. 2. Flavones: These flavonoids are yellow or white pigments that are found in many plants, such as parsley, celery, and chamomile. Flavones have anti-inflammatory, antioxidant, anti-allergic, and anti-cancer effects. Cannaflavin A, B, and C belong to this subcategory. 3. Isoflavonoids:

These flavonoids are mainly found in legumes, such as soybeans, peanuts, and lentils. Isoflavonoids have estrogen-like effects and can modulate hormone levels and metabolism. They also have antioxidant, anti-inflammatory, and anti-cancer properties. 4. Flavanones:

These flavonoids are yellow or orange pigments that are found in citrus fruits, such as oranges, lemons, and grapefruits. Flavanones have antioxidant, anti-inflammatory, anti-microbial, and anti-cancer effects. They can also affect cholesterol levels and blood pressure. 5. Anthoxanthins:

These flavonoids are white or pale yellow pigments that are found in many plants, such as onions, garlic, cauliflower, and cabbage. Anthoxanthins have antioxidant, anti-inflammatory, anti-microbial, and anti-cancer effects. They can also modulate blood sugar levels and prevent oxidative damage. 6. Anthocyanins:

These flavonoids are responsible for the red, purple, or blue color of many fruits and flowers. They are found in berries, grapes, eggplants, and red cabbage. They have antioxidant, anti-inflammatory, anti-cancer, and neuroprotective effects. Cannabis produces several anthocyanins, such as cyanidin, delphinidin, malvidin, pelargonidin, peonidin, and petunidin.

These Six Subgroups Contain More Than 20 Different Flavonoids That Have Been Identified in Marijuana Plants

Here are the nine most important ones and their therapeutic effects: 1. Cannflavins A, B, C:

- Cannflavin A: This is a prenylated flavone that is unique to cannabis. Cannflavin A has potent anti-inflammatory effects that are 30 times more effective than aspirin. Cannflavin A may also inhibit the growth of certain cancer cells and protect the brain from oxidative stress. - Cannflavin B: Another prenylated flavone that is unique to cannabis. Cannflavin B has similar anti-inflammatory effects as cannflavin A but with a different chemical structure. Cannflavin B may also have anti-fungal and anti-microbial properties. - Cannflavin C: A geranylated flavone that is unique to cannabis. Cannflavin C has less anti-inflammatory effects than cannflavin A and B but has more antioxidant effects. Cannflavin C may also have neuroprotective effects by reducing the accumulation of amyloid-beta plaques in Alzheimer's disease. 2. Apigenin:

This is a flavone that is also found in chamomile, parsley, celery, and other plants. Apigenin has anti-inflammatory, anti-anxiety, anti-cancer, and estrogenic effects. Apigenin may also modulate the activity of certain enzymes that metabolize cannabinoids, thus affecting their bioavailability and potency. 3. Luteolin:

This is another flavone that is also present in many fruits and vegetables. Luteolin has anti-inflammatory, anti-oxidant, anti-diabetic, and anti-cancer effects. Luteolin may also inhibit the growth of bacteria and fungi that can cause infections or spoilage of cannabis products. 4. Kaempferol:

This is a flavonol that is also abundant in tea, kale, beans, broccoli, spinach, and other plants. Kaempferol has anti-inflammatory, anti-oxidant, anti-diabetic, anti-cancer, and neuroprotective effects. Kaempferol may also enhance the activity of endocannabinoids, the natural cannabinoids produced by our bodies. 5. Quercetin:

This is another flavonol that is also found in many fruits, vegetables, seeds, and grains; for example, red onions, capers, and cabbage. Read the full article

#cannabisterpenes #Flavonoids #MEDICALCANNABIS

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dietsart · 2 years ago

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Benefits Of Coconut Water ✅

• Hydration - It is rich in electrolytes like potassium, sodium, magnesium, and calcium, which help replenish the body's fluids and maintain proper hydration levels

• Nutrient-rich - Coconut water contains essential nutrients such as vitamin C, vitamin B-complex, amino acids, and minerals

• Antioxidant properties - Coconut water contains antioxidants that help combat free radicals and reduce oxidative stress in the body

• Weight management - It can be a suitable alternative to sugary beverages and can aid in weight management or weight loss efforts when consumed as part of a balanced diet

• Digestive health - The natural enzymes in coconut water, such as catalase, phosphatase, and diastase, can support digestion and promote a healthy gut

• Skin benefits - Its hydrating properties can contribute to healthy, moisturized skin, and its antioxidants may help combat oxidative damage that can contribute to premature aging

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piooo · 2 years ago

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Living beings should undergo antioxidation!

I often see people mistakenly associating antioxidation with the need to brighten dull skin. This is a big misconception! Regardless of who you are, as long as you are alive and exposed to the sun, if you want your skin to be in good condition, you need antioxidation!

1️⃣ Why antioxidation?

The real purpose of antioxidation is to protect our skin from free radicals. I'll simplify this complex process: Cells are exposed to external stimuli (such as UV rays and environmental pollution) → Free radicals are produced → Oxidative damage occurs (breaking down substances like proteins, damaging cell structures) → Long-term accumulation disrupts the skin's dynamic balance → Manifests on the skin's surface (dullness, sagging, wrinkles).

2️⃣ There are two approaches to antioxidation: 1. Targeting the free radicals themselves, 2. Preventing free radicals from causing damage.

1. Targeting free radicals themselves: Superoxide dismutase (SOD), catalase, and glutathione peroxidase are natural antioxidants produced within our bodies. Many advertisements claim that consuming or applying SOD can supplement its levels, but the skin cannot absorb such large molecules, and those consumed orally are inactivated by stomach acid.

2. Preventing free radical damage: To simplify, there are three categories here:

- Vitamins: Vitamin C (VC) and Vitamin E (VE).

- Polyphenols: Plant extracts like green tea extract, resveratrol, EGCG, curcumin, etc., are skincare ingredients derived from plants.

- Others: Thioglycolic acid, fullerenes, astaxanthin, idebenone, coenzyme Q10.

3️⃣ How to choose antioxidation products? Consider the following factors:

1. Ingredients: Look for products that contain antioxidants such as vitamin C, vitamin E, green tea extract, moringa extract, tea polyphenols, etc. These ingredients can neutralize free radicals and reduce oxidative stress.

2. Brand reputation: Choose reliable brands and manufacturers to ensure product quality and effectiveness.

3. Skin type suitability: Choose products suitable for your skin type. For example, if you have sensitive skin, opt for gentle formulations or antioxidation products specifically designed for sensitive skin.

Product type: Antioxidation products come in various forms, including eye creams, serums, masks, etc. Choose the type that suits your preferences and usage habits.

For example, Viicode eye cream is a typical antioxidation product that focuses on eye skin care. This brand is known for its expertise in eye care and their eye cream is designed to fade dark circles, reduce eye bags, and minimize fine lines through antioxidation.

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nootropicsaustralia · 4 years ago

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Ashwagandha's Health Benefits According to Science

Ashwagandha (withania somnifera) is popularly known as the king of Ayurvedic herbs. Ayurveda is a form of alternative medicine based on Indian principles of natural healing. It is an incredibly healthy botanical, often referred to as Indian Ginseng. It is a small plant with yellow flowers that is native to India and North Africa.

It is classified as an adaptogenic herb, and while all adaptogens reduce stress (cortisol), ashwagandha’s ability to do so is superior to the rest.

Ashwagandha has many benefits for the brain, where it can increase energy, sharpen focus, and reduce symptoms of anxiety and depression. It has been used this way for over 3,000 years.

Its name literally means “smell of a horse” since it was said to bestow the strength and stamina of a horse on anyone who used it. An Ayurvedic scholar from 100BC, Charaka, said of Ashwagandha, “One obtains longevity, regains youth, gets a sharp memory and intellect and freedom from diseases, gets a lustrous complexion, and strength of a horse.”

The most well-known active ingredients in Ashwagandha are withanolides. Alongside these valuable compounds are many other beneficial elements, including flavonoids and antioxidants such as catalase, superoxide dismutase and glutathione, which is known as the “mother of all antioxidants.” It also contains alkaloids, amino acids (including tryptophan), neurotransmitters, sterols, tannins, lignans and triterpenes. It is these valuable compounds together that allow for ashwagandha’s hugely beneficial pharmacological activities.

Due to the combined benefits of the herb’s valuable compounds, we used a 60:1 full-spectrum concentrated extract, which is made up of at least 5% withanolides. This means that each 100mg serve in a Savvy product is equivalent to 6grams of this superherb!

The reason we love it in our Savvy products is because Ashwagandha has been proven to:

Reduce stress, anxiety, and mental fatigue; and

Increase mood, enhance brain function and improve memory; and

Boost performance + energy while being a potent anti-inflammatory and antioxidant; and

Support healthy brains and hearts.

We will now delve into the scientific evidence behind the benefits of this amazing herb. For each scientific resource, at Savvy, we have referenced the study, linked to it and also provided an interesting quote from the study. Occasionally, we will also provide further commentary on the study.

Please note that we have referenced the scientific literature that support the benefits of ashwagandha, and to make it easier to read, we have 'indented' every second resource.

Each reference will have a quoted excerpt from the scientific literature, and occasional observations made about the evidence as well.

We really hope you enjoy a look into the many years of research we have compiled when formulating Savvy...

Benefit 1 - Ashwagandha can reduce stress, anxiety, and mental fatigue

Ashwagandha’s chief benefit is that it actually annihilates stress in the body. Ashwagandha improves our resistance to stress and studies show that it thereby improves people’s self-assessed quality of life. Ashwagandha is extremely dynamic in how it combats stress and fatigue!

The study, below, found ashwagandha lowered stress and anxiety by over 60% from consistent use. The reference to the study is:

Chandrasekhar, K. et al. ‘A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults.’ in Indian Journal of psychological medicine. Volume 34, issue 3, July 2012, pp 255-262. [https://www.ncbi.nlm.nih.gov/pubmed/23439798]

After the findings in this study, the authors concluded:

“The findings of this study suggest that a high-concentration full-spectrum Ashwagandha root extract safely and effectively improves an individual's resistance towards stress and thereby improves self-assessed quality of life.”

The above study found that Ashwagandha helps with multiple levels of stress, these being cortisol levels, anxiety and insomnia. In the study, 64 healthy participants were enrolled, between the ages of 18 and 54. Half were given Ashwagandha daily for 60 days, and the other half got a placebo.

The Ashwagandha group saw improvements to their stress baseline by 69.7%, 64.2%, and 75.6%. These improvements were across all three measures including cortisol, anxiety, and insomnia.

The below graph from this trial clearly shows the power of this herb as it influences the body over 60 days from baseline!

PSS is the Perceived Stress Score (which dropped by 44% over 60 days)

GHQ-28 measures levels of anxiety, nervousness, social dysfunction, depression. (Levels of which dropped by 72.3% over 60 days)

DASS (Depression Anxiety Stress Scale) (Levels of which dropped by 71.6% over 60 days)

Serum Cortisol levels - (useful to assess the effect of the treatment on cortisol (the stress hormone in your body) level) (Which dropped by 27.9% over 60 days)

Further scientific evidence that support the benefits of Ashwagandha:

Auddy, B. et al. ‘A Standardized withania somnifera extract significantly reduces stress-related parameters in chronically stressed humans: A double-blind, randomized, placebo-controlled study‘ in JANA, Volume 11, Issue 1, 2008, pp 50-56.

[https://blog.priceplow.com/wp-content/uploads/2014/08/withania_review.pdf]

“This study determined that daily consumption of standardised withania somnifera extract...reduced experimental feelings of stress and anxiety.”

Andrade, C. et al. ‘A double-blind, placebo-controlled evaluation of the anxiolytic efficacy ff an ethanolic extract of withania somnifera.’ in Indian journal of psychiatry. Volume 42, Issue 3, July 2000, pp 295-301.

[https://www.ncbi.nlm.nih.gov/pubmed/21407960]

In the above study, over 6 weeks, 88.2% of the people who took ashwagandha reported a reduction in anxiety.

“It is concluded that this ethanolic extract of Withania somnifera has useful anxiolytic potential.”

Bhattacharya, SK. et al. ‘Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides: an experimental study.’ in Phytomedicine: international journal of phytotherapy and phytopharmacology. Volume 7, Issue 6, December 2000, pp 463-469.

[https://www.ncbi.nlm.nih.gov/pubmed/11194174]

“The investigations support the use of WS as a mood stabilizer in clinical conditions of anxiety and depression in Ayurveda.”

Head, K and Kelly, G. ‘Nutrients and Botanicals for Treatment of Stress: Adrenal Fatigue, Neurotransmitter Imbalance, Anxiety, and Restless Sleep’ in Alternative Medicine Review, Volume 14, Issue 2, 2009, pp 114-140.

[https://www.spectracell.com/media/uploaded/2/0e2016801_266fullpaper2009altmedrevnutrientsforthetreatmentofstressfatigueandinsomnia.pdf]

“...it [Ashwaganda] has shown anti-stress and anabolic activity”

Cooley, K. et al. ‘Naturopathic Care for Anxiety: A Randomized Controlled Trial ISRCTN78958974’ in PLOS one, 2009.

[http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0006628]

In the above study, when anxiety levels were measured after the 12-week period, the group who received ashwagandha had anxiety scores that decreased by 55 percent and the psychotherapy group’s scores decreased by 30.5 percent. Showing that Ashwagandha can even outperform psychotherapy.

“Seventy-five participants (93%) were followed for 8 or more weeks on the trial. Final BAI scores decreased by 56.5% (p<0.0001) in the NC group… Significant differences between groups were also observed in mental health, concentration, fatigue, social functioning, vitality, and overall quality of life with the NC group exhibiting greater clinical benefit. No serious adverse reactions were observed in either group.”

Benefit 2 - Ashwagandha can increase mood, sharpen focus and enhance memory

Ashwagandha supplements may improve mood, brain function, memory, reaction times and the ability to perform tasks.

Scientific Studies:

Pingali, U. et al. ‘Effect of standardized aqueous extract of Withania somnifera on tests of cognitive and psychomotor performance in healthy human participants.’ in Pharmacognosy research. Volume 6, Issue 1, pp 12-18.

[https://www.ncbi.nlm.nih.gov/pubmed/24497737]

“These results suggest that Withania somnifera extract can improve cognitive and psychomotor performance”

Kurapati, KR. et al. ‘Ashwagandha (Withania somnifera) reverses β-amyloid1-42 induced toxicity in human neuronal cells: implications in HIV-associated neurocognitive disorders (HAND).’ in PLos One, Volume 8, Issue 10, October 2013.

[https://www.ncbi.nlm.nih.gov/pubmed/24147038]

“Withania somnifera (WS) also known as 'ashwagandha' is used widely in Ayurvedic medicine as a nerve tonic and memory enhancer.”

Manchanda, S. et al. ‘Aqueous Leaf Extract of Withania somnifera as a Potential Neuroprotective Agent in Sleep-deprived Rats: a Mechanistic Study.’ in Molecular neurobiology. Volume 54, Issue 4, May 2017, pp 3050-3061.

[https://www.ncbi.nlm.nih.gov/pubmed/27037574]

“Modern lifestyle and sustained stress of professional commitments in the current societal set up often disrupts the normal sleep cycle and duration which is known to lead to cognitive impairments. In the present study, we report whether leaf extract of Withania somnifera (Ashwagandha) has potential neuroprotective role in acute stress of sleep deprivation.

This data suggest that Ashwagandha may be a potential agent to suppress the acute effects of sleep loss on learning and memory impairments and may emerge as a novel supplement to control SD-induced cognitive impairments.”

[https://www.ncbi.nlm.nih.gov/pubmed/23439798]

In the above 60-day study in stressed adults, those who took 600 mg per day reported a 79% reduction in severe depression. Interestingly, at the same time, the placebo group reported a 10% increase.

“Ayurvedic classical texts…and clinical studies describe Ashwagandha as a safe and effective adaptogen.”

[https://www.ncbi.nlm.nih.gov/pubmed/11194174]

“The investigations support the use of WS as a mood stabilizer in clinical conditions of anxiety and depression in Ayurveda.”

Sehgal, N. et al. ‘Withania somnifera reverses Alzheimer's disease pathology by enhancing low-density lipoprotein receptor-related protein in liver’ in Proceedings of the National Academy of Sciences of the United Stated of America. Volume 109, Issue 9, February 2012, pp 3510-3515.

[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295277/]

“Withaferin A and withanolide D are the two main withanolides in ashwagandha that are used to improve cognitive function. The above study aimed to test their cognitive-improving abilities, researchers found that they helped to promote cell outgrowth, reverse behavioral deficits and plaque buildup, and reduce amyloid beta burden, which is crucially involved in the development of Alzheimer’s disease.”

Choudhary, D. et al. ‘Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions.’ in Journal of dietary Supplements. Volume 14, Issue 6, November 2017, pp 599-612.

[https://www.ncbi.nlm.nih.gov/pubmed/28471731]

“After eight weeks of study, the ashwagandha treatment group demonstrated significant improvements compared with the placebo group in both immediate and general memory. The treatment group also demonstrated significantly greater improvement in executive function, sustained attention, and information-processing speed.

Ashwagandha may be effective in enhancing both immediate and general memory in people with MCI as well as improving executive function, attention, and information processing speed.”

Benefit 3 - Ashwagandha can boost performance + energy while being a potent anti-inflammatory and antioxidant

Because ashwagandha works as an adaptogen that can reduce the body’s stress hormones, it can help to boost your immune system and reduce inflammation within the body. Due to its positive, calming-yet-energising effects on the brain, and its ability to lower stress hormones, ashwagandha showed improvements in concentration, motivation and stamina in conducted studies.

Scientific studies:

Sandhu, JS. et al. ‘Effects of Withania somnifera (Ashwagandha) and Terminalia arjuna (Arjuna) on physical performance and cardiorespiratory endurance in healthy young adults.’ in International journal of Ayurveda research. Volume 1, Issue 3, July 2010, pp 144-149.

[https://www.ncbi.nlm.nih.gov/pubmed/21170205]

“Withania somnifera may therefore be useful for generalized weakness and to improve speed and lower limb muscular strength and neuro-muscular co-ordination.”

Wankhede, S. et al. ‘Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial.’ in Journal of the International Society of Sports Nutrition. Volume 43, Issue 12, November 2015.

[https://www.ncbi.nlm.nih.gov/pubmed/26609282]

“This study reports that ashwagandha supplementation is associated with significant increases in muscle mass and strength”

Khan, MA. et al. ‘Effect of Withania somnifera (Ashwagandha) root extract on amelioration of oxidative stress and autoantibodies production in collagen-induced arthritic rats.’ in Journal of complementary & integrative medicine. Volume 12, Issue 2, June 2015, pp 117-125.

[https://www.ncbi.nlm.nih.gov/pubmed/25803089]

“The results showed that [withania somnifera] exhibited antioxidant and anti-arthritic activity and reduced inflammation in CIA rats and suggests the potential use of this plant in the treatment of arthritis.” “Similarly, oxidative stress in CIA rats was ameliorated by treatment with different doses of WSAq, as evidenced by a decrease in lipid peroxidation and glutathione-S-transferase “

Yamada, K. et al. ‘A comparison of the immunostimulatory effects of the medicinal herbs Echinacea, Ashwagandha and Brahmi. In Journal of ethnopharmacology. Volume 137, Issue 1, September 2011, pp 231-235.

[https://www.ncbi.nlm.nih.gov/pubmed/21619924]

“Ashwagandha can enhance immune function by increasing immunoglobulin production.”

Trivedi, M. et al. ‘Effect of a Novel Ashwagandha-based Herbomineral Formulation on Pro-inflammatory Cytokines Expression in Mouse Splenocyte Cells: A Potential Immunomodulator’ in Pharmacognosy Magazine, Volume 13, Issue 1, Jan 2017, pp 90-94.

[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407122/]

“These observations indicated that [ashwagandha] has potential effects in downregulating the immune system and might be developed as a useful anti-inflammatory product for various inflammatory disorders.”

Choudhary, B. et al. ‘Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults.’ in AYU: An international quarterly journal of research in Ayurveda. Volume 31, Issue 1, March 2015 pp 63-68.

[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687242/]

“The findings suggest that Ashwagandha root extract enhances the cardiorespiratory endurance and improves QOL [quality of life] in healthy athletic adults.”

Benefit 4- Ashwagandha can support healthy brains and hearts

Ashwagandha has also been considered a healthy supplement for the nervous and cardiovascular systems.

Scientific studies:

[https://blog.priceplow.com/wp-content/uploads/2014/08/withania_review.pdf]

In the above study, the group who took 250 mg of ashwagandha daily had a 36% average decrease in CRP, compared to a 6% decrease in the placebo group

Singh, N. et al. ‘An Overview on Ashwagandha: A Rasayana (Rejuvenator) of Ayurveda’ in African Journal of Traditional, Complementary and Alternative Medicines. Volume 8, Issue 5, pp 208-213.

[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252722/]

“The available scientific data support the conclusion that Ashwagandha is a real potent regenerative tonic (Rasayana of Ayurveda), due to its multiple pharmacological actions like anti-stress, neuroprotective, antitumor, anti-arthritic, analgesic and anti-inflammatory”

Ojha, S and Arya D, ‘Withania somnifera Dunal (Ashwagandha): A Promising Remedy for Cardiovascular Diseases’ in World Journal of Medical Sciences, Volume 4, Issue 2, 2009, pp 156-158.

[https://www.selfhacked.com/wp-content/uploads/2017/12/17.pdf]

Sandhu, J. et al. ‘Effects of Withania somnifera (Ashwagandha) and Terminalia arjuna (Arjuna) on physical performance and cardiorespiratory endurance in healthy young adults’ in International Journal of Ayurveda Research, Volume 1, Issue 3, July 2010, pp 144-149.

[https://search.proquest.com/openview/59746581cde31a08f143c628ea65c441/1?pq-origsite=gscholar]

“Withania somnifera may therefore be useful for generalized weakness and to improve speed and lower limb muscular strength and neuro-muscular co-ordination.”

SummaryI am sure you can now see the amazing benefits of Ashwagandha and why we use it in Savvy.

#Ashwagandha #immunehealth #mentalhealth #adaptogens #Nootropics #productivity #anti-stress #nutrition #increasedPerformance

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didanawisgi · 4 years ago

Link

Abstract

Objective

Oxidative stress contributes to male infertility, and antioxidants have been recommended for treating idiopathic oligoasthenoteratozoospermia (OAT). There is, however, a lack of agreement on the type, dosing, and use of individual antioxidants or combinations thereof. The purpose of this study was to compare the effects of two doses of coenzyme Q10 (CoQ10) on semen parameters and antioxidant status in men with idiopathic OAT.

Methods

In this prospective study, patients with idiopathic OAT received 200 mg/day (n = 35) or 400 mg/day (n = 30) of CoQ10 orally for 3 months. All patients underwent semen analysis according to the fifth editions of the World Health Organization criteria. Total antioxidant capacity (TAC), catalase (CAT) activity, and superoxide dismutase (SOD) activity were measured both before and after treatment.

Results

Treatment with CoQ10 (200 mg/day or 400 mg/day) resulted in a significant increase in sperm concentration from baseline (8.22 ± 6.88 to 12.53 ± 8.11 million/mL, p= 0.019; 7.58 ± 5.41 to 12.33 ± 6.1 million/mL, p= 0.002, respectively), progressive motility (16.54% ±9.26% to 22.58% ±10.15%, p=0.011; 14.22% ±12.85% to 26.1% ±14.52%, p= 0.001, respectively), and total motility (25.68% ± 6.41% to 29.96% ± 8.09%, p= 0.016; 23.46% ± 12.59% to 34.82% ± 14.17%, p= 0.001, respectively). CoQ10 therapy also increased TAC (p= 0.009, p= 0.001, respectively), SOD activity (p= 0.004, p= 0.001, respectively), and CAT activity (p= 0.039, p= 0.024, respectively). Furthermore, antioxidant measures correlated significantly with seminal fluid parameters (r = 0.36–0.76).

Conclusion

CoQ10 supplementation improved semen parameters and antioxidant status in men with idiopathic OAT, with a greater improvement shown in men who took 400 mg/day than in those who took 200 mg/day.

#coenzyme q10 #ubiquinol #men's health #family medicine #save for later

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em1gebrlvbu-blog · 5 years ago

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Boron is an important trace mineral with many potential health benefits

Disclaimer: The content presented here is offered for informational purposes only, and should not be construed as medical advice. You should consult with your physician/care giver regarding your own medical care. I have no financial interest in any of the products or websites that I mention.

I read a variety of published information and studies about potential health benefits of boron supplementation and safety of dosage. I found these to be useful summaries: ___

http://www.health-science-spirit.com/borax.htm Excerpt from Walter Last. The Borax Conspiracy - How the Arthritis Cure has been stopped. 2011.

"Boron is distributed throughout the body with the highest concentration in the parathyroid glands, followed by bones and dental enamel. It is essential for healthy bone and joint function, regulating the absorption and metabolism of calcium, magnesium and phosphorus through its influence on the parathyroid glands. With this boron is for the parathyroids what iodine is for the thyroid.

Boron deficiency causes the parathyroids to become overactive, releasing too much parathyroid hormone which raises the blood level of calcium by releasing calcium from bones and teeth. This then leads to osteoarthritis and other forms of arthritis, osteoporosis and tooth decay. With advancing age high blood levels of calcium lead to calcification of soft tissues causing muscle contractions and stiffness; calcification of endocrine glands, especially the pineal gland and the ovaries; arteriosclerosis, kidney stones, and calcification of the kidneys ultimately leading to kidney failure. Boron deficiency combined with magnesium deficiency is especially damaging to the bones and teeth.

Boron affects the metabolism of steroid hormones, and especially of sex hormones. It increases low testosterone levels in men and oestrogen levels in menopausal women. It also has a role in converting vitamin D to its active form, thus increasing calcium uptake and deposition into bone and teeth rather than causing soft tissue to calcify. Also other beneficial effects have been reported such as improvement of heart problems, vision, psoriasis, balance, memory and cognition." ___

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712861/ Excerpt from Lara Pizzorno, MDiv, MA, LMT. Nothing Boring About Boron. IMCJ Integrative Medicine: A Clinician's Journal. 2015 Aug; 14(4): 35–48.

"Boron has been proven to be an important trace mineral because it (1) is essential for the growth and maintenance of bone; (2) greatly improves wound healing; (3) beneficially impacts the body’s use of estrogen, testosterone, and vitamin D; (4) boosts magnesium absorption; (5) reduces levels of inflammatory biomarkers, such as hs-CRP and TNF-α; (6) raises levels of antioxidant enzymes, such as SOD, catalase, and glutathione peroxidase; (7) protects against pesticide-induced oxidative stress and heavy-metal toxicity; (8) improves brain electrical activity, cognitive performance, and short-term memory in elders; (9) influences the formation and activity of key biomolecules, such as SAM-e and NAD+; (10) has demonstrated preventive and therapeutic effects in a number of cancers, such as prostate, cervical, and lung cancers and multiple and non-Hodgkin’s lymphoma; and (11) may help ameliorate the adverse effects of traditional chemotherapeutic agents." ___

Borax is an compound of boron. Borax (sodium borate) is a natural mineral mined from the earth like salt (sodium chloride), both of which have a long history of being used to preserve food. I read that borax and salt are generally considered safe in small amounts and of similar toxicity (LD50) in large amounts.

California is home to one of the world’s largest borax deposits from which 20 Mule Team Borax has been manufactured since 1891. The product is packaged in its pure form, with no chemical additives. The only processing it receives after its removal from the ground is washing, drying and packaging. The product is 99.5 percent pure, with the remaining 1/2 of 1 percent containing naturally occurring trace minerals, with no risk of heavy metals. I read that pharmaceutical grade borax is not noticeably purer or better.

I wash my hands after handling borax powder and am careful not to get it in eyes. To make a borax solution, I add one US teaspoon (leveled-off, average 4620 mg on my Weighmax CT20 milligram scale) of borax powder and 16 US fluid ounces of purified water into a cooking pot. I heat on the stove until the solution boils for one minute, and stir until the borax is fully dissolved. I pour the solution into a labeled glass jar with lid and store in a dark location at room temperature.

4620 mg borax powder * 0.113 (11.3% boron by weight) = 522.1 mg boron, divided by 64 (number of 1/2 US tablespoons in 16 US fluid ounces water) = 8 mg boron

A 1/2 US tablespoon of this solution with 8 mg boron is comparable to the estimated 5-8 mg/day boron intake for people in parts of the world such as Israel and Western Australia which have high boron levels in the soil and water (and very low rates of arthritis at 1% or less). This amount is well under the Upper Tolerable Limit (UL) of 20 mg/day boron, determined unlikely to cause any adverse effects for healthy people in long term use.

#boron #health

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