#beta cells

[bpod-bpod]

Can't Beat Betas

β-cells of the pancreas produce insulin that regulates levels of blood glucose and malfunction of these cells causes diabetes; the pancreas also contains other non-β-cells (called α-, δ- and γ-cells). In this study a mouse model lacking non-β-cells shows that β-cells alone are sufficient for maintaining normal blood glucose levels, meaning therapies for diabetes may be less concerned with inclusion of other cell types

Read the published research article here

Image from work by Marta Perez-Frances and colleagues

Department of Genetic Medicine and Development, iGE3 and Centre facultaire du diabète, Faculty of Medicine, University of Geneva, Geneva, Switzerland

Image originally published with a Creative Commons Attribution – NonCommercial – NoDerivs (CC BY-NC-ND 4.0)

Published in Nature Metabolism, August 2024

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[humancelltournament]

Human Cell Tournament Round 1

Propaganda!

An autophagosome is a spherical structure with double layer membranes. It is the key structure in macroautophagy, the intracellular degradation system for cytoplasmic contents (e.g., abnormal intracellular proteins, excess or damaged organelles, invading microorganisms). After formation, autophagosomes deliver cytoplasmic components to the lysosomes. The outer membrane of an autophagosome fuses with a lysosome to form an autolysosome. The lysosome's hydrolases degrade the autophagosome-delivered contents and its inner membrane.

Beta cells (β-cells) are specialized endocrine cells located within the pancreatic islets of Langerhans responsible for the production and release of insulin and amylin. Constituting ~50–70% of cells in human islets, beta cells play a vital role in maintaining blood glucose levels. Problems with beta cells can lead to disorders such as diabetes. The function of beta cells is primarily centered around the synthesis and secretion of hormones, particularly insulin and amylin. Both hormones work to keep blood glucose levels within a narrow, healthy range by different mechanisms. Insulin facilitates the uptake of glucose by cells, allowing them to use it for energy or store it for future use.

[skidoodle-doo]

Im gonna throw him against a wall as hard as possible because that is what he deserves

Then I'm gonna hug him and let him HUG me like a plushie and cry after! :D

[funsimplethings]

[justposting1]

COFFEE & its Consequences: 3 science tips you need to know

I’m diving into the effects of coffee on our health and glucose levels. Let’s tackle the beloved ritual of coffee drinking – from the benefits and potential glucose spikes caused by black coffee to the impacts of sugar, sweeteners, and different types of milk. Are you kidding me? Do we really need to add this into our milks? Seriously, it’s super frustrating! Hello, angels, and welcome to The…

[xtruss]

A Stem Cell is a Cell that doesn't have a purpose yet, it turns into something when the body needs a certain cell. There are certain parts of the body that can turnover cells very quickly, some would take longer and others wouldn't. What triggers stem cells is prolonged fasting for 72 hours or even longer. The Fat-burning Effect that Occurs in Fasting Really Helps to Fuel the Stem Cells. Certain parts of the Body that can Turnover New Cells:

• Hippocampus — It is a part of the brain that involves a relay switch with memory and stress responses.

• Beta Cells (Pancreas)

• Bone — The immune cells can be replaced.

• Colon Cells

PKA — A gene that needs to shut down for stem cells to spread and rebuild. Prolonged fasting could lower PKA.

— Dr. Eric Berg DC

[mayordea]

ah, sweet memories.

[edgamz]

i hate drawing full bodies can you tell

[azol-otl]

Prompt Time!

Jason appreciating his hairy partners, can be Tim can be anyone

First things first, this is the first time I'm writing this pairing. Second thing's second, somehow I didn't choose any of my normal suspects and yet here we are. Third thing's third, this is a casual relationship like what they have in canon, but there's mentions of other people.

"You're kind of a freak, you know that Todd?" Jason stops eating her out, which is annoying but whatever he can take a break if he has to. His head game is only like a seven outta ten at best, a point taken off because she's seen him suck a strap like he was trying to steal its soul and really it wasn't even a contest which one he was better at. Instead, he lays his head on her thighs, his stupid stubble rasping against her skin. Black coarse hair against soft white, of course he'd put his head there, the perv. "I don't think you can call me a freak when you nearly choked me to death and fucked my comatose body in corpse position," he says with a raised brow. "Normal shit," she said with a sniff. "Not when you don't tell me ahead of time." Is he still on about this? "I literally told you before I did it." "Yeah, you said 'Hey Jason you ever think about choking' and then pushed me to the ground with your hands on my throat." As if he can complain when he creamed himself while the light left his eyes, the whiner. "Exactly, I told you before I did it." Jason looks like he's gearing up for a fight, which would be pretty great when he's already between her thighs, easy way to get him to pass out during sex again. Instead, like a loser, he decides against it. "So why am I a freak now, Rose?" She could point to any of his kinks, really anything about him at all and have most people agree that he's a freak, but— "You know most guys don't go all crazy eyed at a messy busy, much less—" she gestures to the jungle she was convinced to try out. It wasn't even that she thought it looked bad, but god Jason is such a freak whenever he sees hair on her. Its what brought up his pussy eating game two whole points from when they started this shit. "They're losers and cowards," he scoffs. "Seriously its natural, what kinda guy looks at someone hairless and go 'Yeah, I wanna tap that' it would be like fucking one of those wrinkly cats. Weird and liable to chafe without lots of moisturizer." Rose rolls her eyes but moves the leg Jason isn't on to brush his ribs. The second he feels the hair stroking him he lets out a shudder. Seriously, what a weirdo. "Still a freak Todd," she sing songs, her tone that perfect pitch that annoys everyone she feels like. "If you're gonna be making fun of me, I'll just stick with having sex with Roy," Jason tosses out. "And from a hairy bitch to a bear, you really are predictable aren't you?"

[dykeferatu]

as a fellow type 1. that stem cell transplant post you reblogged also gave me false hope for a second LMAO.... VERY cool research though that hopefully leads to somewhere new for us too!!

eyyyy always glad to meet more type 1s. and yeah still an amazing breakthrough even if it doesn't help us directly!

[bpod-bpod]

Diabetes-beating Betas

Interim results of a clinical trial of pancreatic precursor cells encapsulated in a device as treatment for Type I diabetes: analysis of resulting β cell function and control of glucose levels

Read the published research paper here

Image from work by Bart Keymeulen and colleagues

Diabetes Research Center, Vrije Universiteit Brussel and Universitair Ziekenhuis Brussel, Brussels, Belgium

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in Nature Biotechnology, November 2023

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[lavellane]

ik the implication of the von valancius succession is that our RT is just some random fucking 7th cousin twice removed but i actually think its so funny if leda is theodora's daughter.

[skidoodle-doo]

Hey sorry can you hold my cat for a moment?

YES PLEASE 🥹 *Holds cat*

So precious! :3

[funsimplethings]

[detnu-a-h]

Makarov's voice has me on a chokehold...

[klaytheguildless]

Fiske Starters

Final forms of the starters of Fiske: Sceptile (Grass-Psychic)

Charizard (Fire-Fighting)

Feraligatr (Water-Dark)