#beta cells

[bpod-bpod]

Can't Beat Betas

β-cells of the pancreas produce insulin that regulates levels of blood glucose and malfunction of these cells causes diabetes; the pancreas also contains other non-β-cells (called α-, δ- and γ-cells). In this study a mouse model lacking non-β-cells shows that β-cells alone are sufficient for maintaining normal blood glucose levels, meaning therapies for diabetes may be less concerned with inclusion of other cell types

Read the published research article here

Image from work by Marta Perez-Frances and colleagues

Department of Genetic Medicine and Development, iGE3 and Centre facultaire du diabète, Faculty of Medicine, University of Geneva, Geneva, Switzerland

Image originally published with a Creative Commons Attribution – NonCommercial – NoDerivs (CC BY-NC-ND 4.0)

Published in Nature Metabolism, August 2024

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[humancelltournament]

Human Cell Tournament Round 1

Propaganda!

An autophagosome is a spherical structure with double layer membranes. It is the key structure in macroautophagy, the intracellular degradation system for cytoplasmic contents (e.g., abnormal intracellular proteins, excess or damaged organelles, invading microorganisms). After formation, autophagosomes deliver cytoplasmic components to the lysosomes. The outer membrane of an autophagosome fuses with a lysosome to form an autolysosome. The lysosome's hydrolases degrade the autophagosome-delivered contents and its inner membrane.

Beta cells (β-cells) are specialized endocrine cells located within the pancreatic islets of Langerhans responsible for the production and release of insulin and amylin. Constituting ~50–70% of cells in human islets, beta cells play a vital role in maintaining blood glucose levels. Problems with beta cells can lead to disorders such as diabetes. The function of beta cells is primarily centered around the synthesis and secretion of hormones, particularly insulin and amylin. Both hormones work to keep blood glucose levels within a narrow, healthy range by different mechanisms. Insulin facilitates the uptake of glucose by cells, allowing them to use it for energy or store it for future use.

[skidoodle-doo]

Im gonna throw him against a wall as hard as possible because that is what he deserves

Then I'm gonna hug him and let him HUG me like a plushie and cry after! :D

[funsimplethings]

[justposting1]

COFFEE & its Consequences: 3 science tips you need to know

I’m diving into the effects of coffee on our health and glucose levels. Let’s tackle the beloved ritual of coffee drinking – from the benefits and potential glucose spikes caused by black coffee to the impacts of sugar, sweeteners, and different types of milk. Are you kidding me? Do we really need to add this into our milks? Seriously, it’s super frustrating! Hello, angels, and welcome to The…

[xtruss]

A Stem Cell is a Cell that doesn't have a purpose yet, it turns into something when the body needs a certain cell. There are certain parts of the body that can turnover cells very quickly, some would take longer and others wouldn't. What triggers stem cells is prolonged fasting for 72 hours or even longer. The Fat-burning Effect that Occurs in Fasting Really Helps to Fuel the Stem Cells. Certain parts of the Body that can Turnover New Cells:

• Hippocampus — It is a part of the brain that involves a relay switch with memory and stress responses.

• Beta Cells (Pancreas)

• Bone — The immune cells can be replaced.

• Colon Cells

PKA — A gene that needs to shut down for stem cells to spread and rebuild. Prolonged fasting could lower PKA.

— Dr. Eric Berg DC

[mayordea]

ah, sweet memories.

[edgamz]

i hate drawing full bodies can you tell

[dykeferatu]

as a fellow type 1. that stem cell transplant post you reblogged also gave me false hope for a second LMAO.... VERY cool research though that hopefully leads to somewhere new for us too!!

eyyyy always glad to meet more type 1s. and yeah still an amazing breakthrough even if it doesn't help us directly!

[lavellane]

ik the implication of the von valancius succession is that our RT is just some random fucking 7th cousin twice removed but i actually think its so funny if leda is theodora's daughter.

[bpod-bpod]

Diabetes-beating Betas

Interim results of a clinical trial of pancreatic precursor cells encapsulated in a device as treatment for Type I diabetes: analysis of resulting β cell function and control of glucose levels

Read the published research paper here

Image from work by Bart Keymeulen and colleagues

Diabetes Research Center, Vrije Universiteit Brussel and Universitair Ziekenhuis Brussel, Brussels, Belgium

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in Nature Biotechnology, November 2023

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[detnu-a-h]

Makarov's voice has me on a chokehold...

[skidoodle-doo]

Hey sorry can you hold my cat for a moment?

YES PLEASE 🥹 *Holds cat*

So precious! :3

[funsimplethings]

[klaytheguildless]

Fiske Starters

Final forms of the starters of Fiske: Sceptile (Grass-Psychic)

Charizard (Fire-Fighting)

Feraligatr (Water-Dark)

[prismit]

couldn't find any documentation on how many cells you get from boss rush, so i worked it out myself! (to the best of my abilities anyway lol, also if this info is out there already then i must have missed it in my search 😅 sorry)

quick note: this might not be 100% accurate, since i mostly used math instead of fighting every boss 6 times lol. but i definitely gathered enough data to find a consistent pattern, so if these numbers are off at all, they should at least be VERY close, and at least 0bc and 5bc are definitely correct.

so, here's the numbers for each difficulty!

Concierge: 24 / 25 / 26 / 27 / 28 / 30

Conjunctivius: 40 / 42 / 44 / 46 / 48 / 50

Mama Tick: 32 / 33 / 35 / 36 / 38 / 40

Death: 80 / 84 / 88 / 92 / 96 / 100

Time Keeper: 40 / 42 / 44 / 46 / 48 / 50

Giant: 60 / 63 / 66 / 69 / 72 / 75

Scarecrow: 50 / 52 / 55 / 57 / 60 / 62

Dracula: 80 / 84 / 88 / 92 / 96 / 100

Hand of the King: 80 / 84 / 88 / 92 / 96 / 100

Servants: 47 / 49 / 51 / 54 / 56 / 60

Queen: 80 / 84 / 88 / 92 / 96 / 100

Dracula Final Form: 40 on all difficulties

ALSO: you don't get any more cells than normal from modified bosses or flawless wins. the 4 trials give the same amount as DIY mode, so there's no bonus there as far as cells go.