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queering-ecology · 8 months ago

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Chapter 7. Polluted Politics? Confronting Toxic Discourse, Sex Panic and Eco-Normativity by Giovanna Di Chiro

“Stereotypes and lies lodge in our bodies as surely as bullets. They live and fester there, stealing the body.”—Eli Clare

Queer ecology as defined by Mortimer-Sandilands (2005, 24) “both about seeing beauty in the wounds of the world and taking responsibility to care for the world as it is”. (200)

Environmental justice constructs an eco-politics that defines the environment as our communities: the places where ‘we live, work, play, and learn’ (200). Environmental justice activists embrace inhabited/built places---cities, villages, reservations, agricultural fields, workplaces, poor and low-income neighborhoods next to hazardous industrial facilities as environments worthy of recognition and protection (Di Chiro 1996)

There has been rising environmental anxiety that surrounds cultural fears of exposure to chemical and endocrine-disrupting toxins especially as it relates to the troubling and destabilizing of normal/natural gendered bodies of humans and other animal species aka the “chemical castration” or the “feminization of nature” (Cadbury 1998; Hayes 2002)--rising fears that we are “swimming in a sea of estrogen” (Raloff 1994b, 56; Sumpter and Jobling 1995 173) as a consequence of rising levels of estrogenic, synthetic chemical compounds emitted into our water, air and food known as estrogenic pollution (ova-pollution). (201)

Pop-science warning about the ‘instability of maleness’—warns that the rising incidences of male-to-female gender shifts and intersex conditions observed in the ‘lower’ species of animals, such as frogs, fish, and salamanders, represent the newest ‘canaries in the coalmine’ portending an uncertain fate for human maleness and for the future of ‘normal’ sexual reproduction (Robert 2003) (201) also anti-toxins discourse has concerns about estrogenic chemical toxins disrupting/preventing/disturbing ‘normal’ prenatal physiological development and natural reproductive processes, leading to rising cases of infertility and producing disabled, defective, and even monstrous bodies (201)…

What can develop is a “sex panic” that resuscitates familiar heterosexist, queerphobic, and eugenics arguments classifying some bodies as not normal: mistakes, perversions, burdens (I would add ‘freaks’)…under the guise of laudable goal/progressive goals, a certain type of anti-toxics environmentalism mobilizes knowledge/power of normalcy and normativity and reinforces compulsory social-environmental order based on a dominant regime of what and who are constructed as normal and natural (Davis 1995; Garland-Thompson 1997; McRuer 2006).

Disability becomes an environmental problem and lgbtq people become disabled—the unintended consequences of a contaminated and impure environment, unjustly impaired by chemical trespass. (202) The true scope of the mortality and morbidity of POPs (persistent organic pollutants) becomes distorted by alarmist focus. This fixation ends up de-emphasizing and worse--naturalizing and normalizing other serious health problems associated with POPs that are on the rise: breast, ovarian, prostate and testicular cancers, neurological and neurobehavioral problems, immune system breakdown, heart disease, diabetes and obesity (202).

There is good reason for alarm concerning the continued use and accumulation of toxic chemicals that are wreaking havoc on the health and reproductive possibilities of the living world. Our cumulative exposures to endocrine disruptors, carcinogens, neurotoxins, asthmagens, and mutagens in our normal, everyday lives from our daily contact with plastic water bottles, shampoos, and kitchen cleaners to insect repellents, food preservatives, and factory farmed meats, among others, are most certainly putting at risk the health of our own bodies and our earth. (210) But where should the critical attention lie?

The hyperfocus on the world turning into hermaphrodites participates in a sexual titillation strategy summoning the familiar ‘crimes against’ nature’ credo and inviting culturally sanctioned homophobia while at the same time sidelining and naturalizing ‘normal’ environmental diseases such as cancer (211).

Environmental theory and politics in the US have historically mobilized ideas of the normal, to determine which bodies and environments/landscapes embody the distinctly American values of productive work, rugged individualism, masculinity, independence, potency, and moral virtue upon which environmental advocacy movements should be based (Haraway 1989; Cronon 1991). Critical histories of U.S. environmentalism have revealed the capitalist, patriarchal, colonialist, heteronormative, eugenicist, and ableist histories underlying its “progressive” exterior (Boag 2003; Darnovky 1992; Evans 2002; Gaard 2004; Jaquette 2005; Sutter 2001).

Eco-normativity (or eco[hetero]normativity) appear in alarmist discourse in the anti-toxins arm of the environmental movement. Their alarm about contaminants effect on sex/gender appeals to preexisting cultural norms of gender balance, normal sexual reproduction and the balance of nature. The use of “anti-normal” “anti-natural” in antitoxins discourse is highly questionable and risks reinforcing the dominant social and economic order (the forces actually responsible for environmental destruction and toxic contamination of all our bodies and environments) by naturalizing the multiple injustices that shore it up”…and thus creates what the author terms, polluted politics.

#queer ecologies: sex nature politics desire #econormativity #heteronormativity #critical ecology #queer ecology #ecology #environmental contamination #persistent organic pollutants #toxins #anti toxins #eugenics #ecofeminism #environmental politics #ecological science #environmental science

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healthcarehubhh · 4 months ago

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Immunohistochemistry Boosts Drug Development Success

Immunohistochemistry (IHC) is a technique used to detect antigens (proteins) in cells of a tissue section by exploiting the principle of antibodies binding specifically to antigens in biological tissues. IHC takes advantage of the principles of an antibody's ability to recognize and bind to a specific site called an antigen. The site is usually a protein that is present on the surface or inside cells. The presence of the protein, or antigen, may indicate something important about the function or disease state of the cell or tissue. Applications of IHC in Diagnostics Immunohistochemistry is widely used in clinical diagnostics for detecting biomarkers associated with diseases. It helps pathologists to accurately diagnose cancer type and stage by identifying molecular markers in tumor cells. For example, breast cancers diagnosed as luminal A-type are estrogen receptor positive as detected by IHC. This guides treatment decision towards hormone therapy. IHC also aids in sub-classifying lymphomas and determining tumor grade in prostate cancer biopsies. In research, IHC is utilized for protein localization studies to gain insights into disease mechanisms. Role in Drug Development Pharmaceutical companies rely on IHC throughout the drug development process. During target identification and validation, IHC confirms the expression and localization of potential drug targets in diseased tissues. This helps assess whether modulating the target could provide therapeutic benefit. During preclinical development, IHC on animal models establishes target engagement and desired downstream effects of drug candidates. Later in clinical trials, IHC on patient biopsies evaluates target expression, engagement and related biomarkers to monitor drug response. Post-marketing, IHC supports companion diagnostic development to identify patients most likely to benefit from a targeted therapy.

#Immunohistochemistry Share #Immunohistochemistry Demand #Immunohistochemistry Analysis

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yourcancerguru · 4 months ago

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A Brief Guide to Natural Bath, Body, and Personal Products

Choosing bath, body, and personal products that contain natural ingredients is crucial, especially for those with a diagnosis of cancer. Conventional cancer treatments like chemotherapy, immunotherapy, and radiation can cause skin sensitivity, making it prone to irritation. Natural ingredients are typically gentler and less likely to cause adverse reactions. Many conventional body products contain potentially harmful chemicals like parabens, phthalates, and synthetic fragrances that can increase one’s chemical burden and disrupt the balance of hormones in the body. By using natural products, you can reduce exposure to chemicals, support your immune system, and allow your body to focus on healing. In addition, natural body products can nourish, soothe, hydrate, and heal the skin, which is especially important for skin that has been damaged by treatment. When choosing cosmetics, shampoos, conditioners, soaps, lotions, sunscreen, and toothpaste, here’s the long list of ingredients to avoid.

Most common toxic ingredients found in cosmetics, shampoos, conditioners, body washes, and moisturizers:

Parabens - May be listed as methylparaben, polyparaben, isoparaben, or butylparaben. These can be directly absorbed through skin and induce estrogen-like activity on the body.

Phthalates - Also listed as butyl benzyl phthalate (BBP), Di-n-butyl phthalate (DBP), Di-ethylhexyl phthalate (DEHP), and Diethyl phthalate (DEP). These are hormone disrupting chemicals that may be linked to breast and prostate cancers, as well as many other diseases. It’s important to note that many perfumes use phthalates, but often times it is not listed on the label. If you choose to go phthalate-free, avoid wearing perfume and/or choose essential oils instead.

Triclosan - This ingredient is commonly found in antibacterial soap. Triclosan has been shown to suppress NK cell activity. NK cells are natural killer cells that help our body constantly fight against infection, as well as cancer.

Toxic chemicals most commonly found in deodorant:

Aluminum and aluminum zirconium- Both can have an estrogen-like activity in the body. This is extremely important to consider when choosing deodorant, as most conventional deodorants contain aluminum.

Toxic chemicals most commonly found in toothpaste:

Triclosan- An organic compound with antibacterial properties that can disrupt thyroid function and antibiotic resistance. It's also been linked to gum recessions and a variety of cancers.

Sodium lauryl sulfate (SLS) - A detergent and cosmetic ingredient that can irritate the gums and cause canker sores, gum recessions, and allergic reactions.

Fluoride - Can be toxic if ingested in large amounts, causing nausea, vomiting, and headaches.

Titanium dioxide - The Environmental Working Group classifies this ingredient as a possible carcinogen.

Microbeads - Made from insoluble plastics that can't be digested and can end up in waterways, where they can absorb toxic chemicals and harm marine life.

MEA, DEA, and TEA - Methylating compounds that can weaken the liver and kidneys and lead to cancer.

Propylene glycol- A synthetic chemical compound that can irritate the skin, eyes, lungs, and mucous membranes. It's also a strong carcinogen.

Saccharin - An artificial sweetener that can cause coughing, nausea, vomiting, and diarrhea. Saccharin has also been linked to many different kinds of cancers.

Diethanolamine (DEA) - A chemical used as a foaming agent that can cause organ-system toxicity. A 1998 study linked topical application of DEA to cancer in animals.

Aspartame - Consumption of aspartame could potentially lead to illnesses such as Alzheimer's, diabetes, and multiple sclerosis. Aspartame is also linked to various kinds of cancers.

Check out my Pinterests with specific recommendations for clean and safe body products approved by the Environmental Working Group (EWG.org) for 2024.

Shampoos and Body Washes

https://pin.it/6zEkeukCI

Moisturizers

https://pin.it/1i1QUTecp

Sunscreens

https://pin.it/3JaNYHM7l

Face Wash

https://pin.it/4MqigKwCV

Toothpaste

https://pin.it/5lfwEbrRP

#natural body products #natural shampoo #natural body wash #natural moisturizers #natural suscreen #natural face wash #natural toothpaste #EWG #organicbeauty #cancer #integrativeoncology

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xtruss · 5 months ago

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Image Credit: Maria I. Morasso, Ph.D.; National Institutes of Health

Scientists Discover A New Hormone That Can Build Strong Bones

Researchers at UCSF and UC Davis solved a long-standing puzzle on how the bones of breastfeeding women stay strong even as they lose calcium to milk.

— By Sarah C.P. Williams | University of California San Francisco | July 10, 2024

A newly discovered hormone that keeps the bones of breastfeeding women strong could also help bone fractures heal and treat osteoporosis in the broader population. Researchers at UC San Francisco and UC Davis showed that in mice, the hormone known as Maternal Brain Hormone (CCN3) increases bone density and strength.

Their results, published July 10 in Nature, solve a long-standing puzzle about how women’s bones remain relatively robust during breastfeeding, even as calcium is stripped from bones to support milk production.

“One of the remarkable things about these findings is that if we hadn’t been studying female mice, which unfortunately is the norm in biomedical research, then we could have completely missed out on this finding,” said Holly Ingraham, PhD, the senior author of the new paper and a professor cellular molecular pharmacology at UCSF. “It underscores just how important it is to look at both male and female animals across the lifespan to get a full understanding of biology.”

More than 200 million people worldwide suffer from osteoporosis, a severe weakening of the bones that can cause frequent fractures. Women are at particularly high risk of osteoporosis after menopause because of declining levels of the sex hormone estrogen, which normally promotes bone formation. Estrogen levels are also low during breastfeeding, yet osteoporosis and bone fractures are much rarer during this time, suggesting that something other than estrogen promotes bone growth.

A Hormone That Is Only Produced During Lactation

During lactation, CCN3 (red) appears in the female brain in neurons adjacent to other cells, called tanycytes (cyan). Image by Ingraham Lab

Ingraham’s lab previously discovered that in female mice, but not male mice, blocking a particular estrogen receptor found in select neurons in a small area of the brain led to huge increases in bone mass. They suspected that a hormone in the blood was responsible for the super-strong bones but, at the time, could not find it – a quest that was further protracted during the worldwide pandemic.

In the new work, Ingraham and collaborators carried out an exhaustive search for this bone-building hormone and finally pinpointed CCN3 as the factor responsible in mutant females. Initially, the team was surprised by this result, as CCN3 did not fit the typical profile of a secreted hormone from neurons.

Their doubts vanished after they found CCN3 in the same brain region in lactating female mice. Without the production of CCN3 in these select neurons, lactating female mice rapidly lost bone, and their babies began to lose weight, confirming the importance of the hormone in maintaining bone health during lactation. Based on this discovery, they now refer to CCN3 as Maternal Brain Hormone (MBH).

Hormone Strengthens Bones in Young, Old, Male and Female Mice

Bone loss happens not only in post-menopausal women, but is also common in:

Breast cancer survivors taking certain hormone blockers

Younger, highly trained elite female athletes

Older men whose relative survival rate is poorer than women after a hip fracture

When strategies to increase circulating CCN3 were implemented in young adult and older female or male mice, their bone mass and strength increased dramatically over the course of weeks. In some female mice who lacked all estrogen or were very old, CCN3 was able to more than double bone mass.

When Ingraham’s scientific collaborator, Thomas Ambrosi, PhD, an assistant professor of orthopaedic surgery at UC Davis, tested these bones, he was surprised by their strength.

“There are some situations where highly mineralized bones are not better; they can be weaker and actually break more easily,” he explained. “But when we tested these bones, they turned out to be much stronger than usual.”

Ambrosi looked closely at the stem cells within the bones that are responsible for generating new bone and found that when these cells were exposed to CCN3, they were much more prone to generate new bone cells.

A Hydrogel Patch Heals Fractures in Mice

To test the ability of the hormone to assist in bone healing, the researchers created a hydrogel patch that could be applied directly to the site of a bone fracture, where it would slowly release CCN3 for two weeks. In elderly mice, bone fractures don’t usually heal well. However, the CCN3 patch spurred the formation of new bone at the site of the fracture, contributing to youthful healing of the fracture.

“We’ve never been able to achieve this kind of mineralization and healing outcome with any other strategy,” Ambrosi said. “We’re really excited to follow it up and potentially apply CCN3 in the context of other problems, such as regrowing cartilage.”

The researchers plan to carry out future studies on the molecular mechanisms of CCN3, its levels in breastfeeding women, as well as the potential of the hormone to treat a variety of bone conditions.

Muriel Babey, MD, a co-first author and mentored physician-scientist in the Division of Endocrinology at UCSF, is keen to begin asking how CCN3 impacts bone metabolism in clinically relevant disease settings. Partnering with the UCSF Catalyst program, William Krause, PhD, a senior scientist and co-lead on this project will begin translating these new results.

“Bone loss happens not only in post-menopausal women but often occurs in breast cancer survivors that take certain hormone blockers; in younger, highly trained elite female athletes; and in older men whose relative survival rate is poorer than women after a hip fracture,” Ingraham said. “It would be incredibly exciting if CCN3 could increase bone mass in all these scenarios.”

William Krause, PhD, left; Muriel Babey, MD, center; and Holly Ingraham, PhD, right, at the Ingraham Lab in Arthur and Toni Rembe Rock Hall at the UCSF Mission Bay campus. Photo by Susan Merrell

— Authors: Other UCSF authors include Candice B. Herber, Zsofia Torok, Joni Nikkanen, Ruben Rodriquez, Saul Villeda and Fernanda Castro-Navarro. Other UC Davis authors include Kun Chen, Erika E. Wheeler, J. Kent Leach, and Nancy E. Lane. Please see the paper for a complete author list.

#Aging #Biochemistry | Molecular Biology #Neurology #Neurosciences #Osteoporosis #Bone Health #Women’s Health

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importanceofdim · 8 months ago

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Unlocking the Potential: Exploring Diindolylmethane (DIM) Research

In the realm of nutritional supplements, diindolylmethane (DIM) has been garnering increasing attention for its potential health benefits. Derived from cruciferous vegetables like broccoli, Brussels sprouts, and kale, DIM has been the subject of numerous studies investigating its effects on human health. Let's delve into the exciting world of DIM research and uncover the potential it holds for our well-being. Get more info about diindolylmethane DIM supplement resources click here.

Understanding DIM:

Diindolylmethane is a compound formed in the body when we digest certain vegetables. It belongs to a class of compounds known as indoles, which are sulfur-containing chemicals found in cruciferous vegetables. DIM is particularly abundant in broccoli, cauliflower, cabbage, and other vegetables of the Brassica genus.

Cancer Prevention and Treatment:

One of the most compelling areas of DIM research revolves around its potential in cancer prevention and treatment. Studies have suggested that DIM may have anti-cancer properties, particularly in hormone-related cancers such as breast, prostate, and cervical cancers.

Research indicates that DIM may modulate estrogen metabolism, potentially reducing the risk of estrogen-driven cancers. It is believed to promote the conversion of estrogen into less potent forms, which may help prevent the proliferation of cancer cells. Additionally, DIM has shown promise in inhibiting tumor growth and inducing apoptosis (cell death) in cancer cells in various laboratory studies.

Hormonal Balance:

DIM's ability to modulate estrogen levels also makes it a subject of interest in hormone-related conditions such as polycystic ovary syndrome (PCOS) and menopausal symptoms. By promoting a balance in estrogen metabolism, DIM may help alleviate symptoms such as irregular menstrual cycles, hormonal acne, and mood swings associated with hormonal imbalances.

Immune Function:

Emerging research suggests that DIM may also play a role in supporting immune function. By promoting a healthy balance of hormones and reducing inflammation, DIM could potentially bolster the body's immune response, helping it fend off infections and diseases more effectively.

Cardiovascular Health:

Some studies have explored the potential cardiovascular benefits of DIM. It is thought to exert antioxidant and anti-inflammatory effects that may help protect against cardiovascular diseases such as atherosclerosis and heart disease. By reducing oxidative stress and inflammation, DIM may contribute to overall heart health.

Considerations and Future Directions:

While the research surrounding DIM is promising, it is essential to approach it with a critical eye. Many studies have been conducted in vitro or on animals, and more human clinical trials are needed to fully understand DIM's effects and optimal dosage for various health conditions.

Additionally, individual responses to DIM may vary, and it's essential to consult with a healthcare professional before starting any new supplement regimen, especially for individuals with pre-existing medical conditions or those taking medications.

In conclusion, diindolylmethane represents a fascinating area of research with the potential to positively impact human health in various ways, from cancer prevention to hormonal balance and immune support. As scientists continue to unravel its mechanisms and conduct further studies, DIM may emerge as a valuable tool in promoting overall well-being and longevity.

#diindolylmethane_research

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delifoodsmanufacturer · 9 months ago

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Debunking The Lie That Royal Jelly Causes Breast Cancer

Royal jelly, a milky treasure secreted by worker bees, has garnered widespread recognition as a natural health booster. As a leading producer and exporter, China plays a crucial role in the global apiculture market, contributing a significant portion of the world's royal jelly. However, unfounded rumors have cast a shadow on its reputation, alleging high estrogen content and a potential link to breast cancer. Let's delve deeper and dispel these myths with scientific evidence. 1.Examining the Estrogen Content: Royal jelly boasts a diverse portfolio of nutrients, including proteins, vitamins, and minerals, renowned for its various health benefits like anti-inflammatory and anti-tumor properties. While estrogen, a crucial hormone primarily produced by the ovaries, is present in all animal-derived food, research reveals minimal traces in royal jelly. In fact, over 88% of samples contained less than 1.0 micrograms per kilogram (μg/kg), significantly lower than commonly consumed foods. These negligible levels effectively debunk the exaggerated claims about high estrogen content in royal jelly. 2.Separating Fact from Fiction: Does Royal Jelly Increase Breast Cancer Risk? Based on established guidelines and residue limits set by international organizations, a person would need to consume an unimaginable 3 kilograms of royal jelly daily to pose any potential harm. This figure stands in stark contrast to the recommended dosage of 10-15 grams, highlighting the absurdity of the claim. Furthermore, extensive research, including long-term studies, has found no link between royal jelly consumption and an increased risk of breast cancer. This scientific evidence provides reassurance about the safety of incorporating royal jelly into your diet. 3.A Note on Cautious Consumption: While generally safe, it's essential to be mindful when consuming any health supplement, including royal jelly. Individuals with allergies, pregnant women, and adolescents are advised to consult a healthcare professional before including it in their diet. In summary, rumors about royal jelly’s high estrogen content and its link to breast cancer lack scientific basis. The benefits of this natural treasure far outweigh unfounded claims, and through responsible consumption, individuals can safely explore its many health advantages. Read the full article

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qualityherb · 1 year ago

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The Health Benefits of Icariin: A Natural Remedy for Various Ailments

Icariin Extract, a flavonoid compound found in the Epimedium plant, has been used in traditional Chinese medicine for centuries. Recently, it has gained popularity in the Western world for its numerous health benefits. Here are some of the benefits of icariin:

Increases libido: Icariin has been shown to increase sexual desire and improve erectile function in men. It works by increasing nitric oxide levels in the body, which relaxes blood vessels and improves blood flow to the genital area.

Boosts bone health: Icariin has been found to positively affect bone health by increasing bone density and reducing the risk of osteoporosis. It works by stimulating the production of osteoblasts, cells responsible for bone formation.

Reduces inflammation: Icariin has anti-inflammatory properties that can help reduce inflammation. This can be particularly beneficial for those with arthritis and other inflammatory disorders.

Enhances cognitive function: Icariin has been found to improve cognitive function and memory in animal studies. It promotes the growth of new brain cells and increases blood flow to the brain.

Protects the heart: Icariin has been shown to protect the heart by reducing oxidative stress and inflammation. This can help reduce the risk of heart disease and stroke.

Safety precautions (7 contraindications)

Not recommended for pregnant or breastfeeding women due to unknown safety.

Not recommended for individuals with poor liver, kidney, and cardiovascular function as it may cause unknown adverse reactions.

Do not take with medications or health supplements that may affect heart rhythm as they may cause unknown risks, such as asthma medications, antibiotics, cough medicine, cold medicine, antihistamines, thyroid medication, antidepressants, bitter orange, valerian, hawthorn, ginseng, ephedra, coffee, alcohol, cocaine, marijuana, etc.

It is not recommended for individuals with abnormal blood clotting within two weeks before surgery or taking anticoagulants, as it may slow down blood clotting and increase the risk of bleeding. Relevant medication names include aspirin, clopidogrel, diclofenac, ibuprofen, naproxen, dalteparin, enoxaparin, heparin, and warfarin.

It is not recommended for individuals with hormone-sensitive diseases or cancers (such as breast, uterine, or ovarian cancer) due to its potential estrogen-like effects, which may worsen symptoms.

It is not recommended for individuals with low blood pressure or taking related blood pressure-lowering medications, as it may further lower blood pressure. Relevant medication names include captopril, enalapril, losartan, valsartan, diltiazem, Amlodipine, hydrochlorothiazide, and furosemide.

It is not recommended for individuals with a history of allergy to the Berberidaceae family of plants, as it may trigger allergic reactions, such as rash, sweating, or fever.

Icariin Extract can be found in supplement form and is available in various dosages. As with any supplement, it is essential to consult a healthcare professional before taking icariin, especially if you have a pre-existing medical condition or are taking other medications.

Epimedium, Icariin, Icariin Extract

#Icariin

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drudra · 1 year ago

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What are the health benefits of garlic ?

Garlic is widely recognized for its culinary uses and distinct flavor, but it also offers several potential health benefits. Garlic contains various bioactive compounds, including sulfur-containing compounds like allicin, which are believed to contribute to its medicinal properties. Here are some of the potential health benefits associated with garlic:

Immune system support: Garlic has been traditionally used to boost the immune system and help fight off common illnesses like colds and flu. It may have antimicrobial properties that can help combat certain bacteria, viruses, and fungi.

2. Cardiovascular health: Garlic has been associated with potential cardiovascular benefits. It may help lower blood pressure, reduce cholesterol levels (including LDL or "bad" cholesterol), and inhibit blood clotting, which can be beneficial for heart health. These effects may contribute to a decreased risk of heart disease.

3. Antioxidant properties: Garlic contains antioxidants that help protect cells from oxidative damage caused by harmful molecules called free radicals. Antioxidants play a role in reducing inflammation and may contribute to overall health and disease prevention.

4. Anti-inflammatory effects: Some compounds in garlic have anti-inflammatory properties that can help reduce inflammation in the body. Chronic inflammation is linked to various health conditions, including heart disease, cancer, and rheumatoid arthritis.

5. Cancer prevention: Garlic has been studied for its potential cancer-fighting properties. Some research suggests that garlic consumption may be associated with a reduced risk of certain cancers, including those of the stomach, colon, esophagus, and breast. However, more studies are needed to establish conclusive evidence.

6. Improved digestion: Garlic has been used traditionally to aid digestion and alleviate digestive discomfort. It may stimulate the production of digestive enzymes, support the growth of beneficial gut bacteria, and promote healthy digestion.

7. Antimicrobial properties: Garlic has shown antimicrobial activity against various bacteria, viruses, and fungi. It may help combat certain infections, such as those caused by bacteria like E. coli or fungi like Candida.

8. Improved bone health: Some animal studies suggest that garlic may help improve bone health by increasing estrogen levels in females, which can contribute to enhanced bone density.

It's important to note that while garlic offers potential health benefits, it should not be considered a substitute for medical treatment or professional advice. It's always advisable to consult with a healthcare professional before making any significant changes to your diet or using garlic supplements, especially if you have specific health conditions or are taking medications.

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freebunni · 1 year ago

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Best Cruelty free Mascara

With treatments from eyelash extensions to perming, it’s fair to say that we’re more lash-obsessed than ever. We’ve all been there, from bending our mascara wand to trying the spoon technique. Is it really time to start learning about natural mascara? We sure think so! If this is your first time venturing into the world of natural makeup, no worries. We’re covering all the in’s and out’s of our Best Cruelty free Mascara, so you can make the best choice for your beauty needs (beauty is power!).

Why choose a natural mascara?

We don’t want to be fearmongers. We agree, makeup is a fun and empowering form of self expression. The truth is, your skin absorbs what you put on it — a fact you should be even more concerned about in regards to your eye area.

First of all, what makes a mascara “natural?” The truth is, there’s no set definition for what “natural” means. A good place to start would be to take a look at the ingredients in your typical drugstore mascara. Do you know what all of them are? Another simple test is to ask yourself if you can even pronounce them. Did you pass the test? When in doubt, ask the company, or look up the ingredient on EWG’s Skin Deep database.

In looking for the best natural mascaras, we’ve narrowed down our list to high performing formulas that do without the following harmful ingredients:

Parabens: synthetic preservatives that can mimic estrogen, and have been linked to breast cancer.

Ureas: ureas such as diazolidinyl urea preserve cosmetic products by releasing formaldehyde — a known human carcinogen.

Phthalates: industrial plasticizers used to mix together cosmetic ingredients, making mascara easy to apply. But they’ve been linked to severe hormone disruption.

Dimethicone: Dimethicone is used to achieve a smooth, waterproof finish. It’s hard to get off of lashes afterwards, though, and can lead to brittle lashes — especially if you wear mascara on a daily basis.

Fragrance: The FDA lets companies label any mixture of fragrance ingredients as simply “fragrance” without having to list them all. So even if you’re trying to stay away from phthalates, they might still be in your mascara formula under a disguise.

Animal Testing: Because why should we ever have to subject other living beings to cruelty for our benefit? And the fact that a company would need to test a potentially hazardous ingredient or product on an animal should raise red flags about its safety in the first place.

It’s time to put individuality back into not just our makeup looks, but also in choosing the products we trust our delicate lashes and sensitive eyes with. Natural mascaras are the way to go for gorgeous eyelashes that will last, without the unnecessary eye irritation. What type of mascara do you prefer for your makeup looks?

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usfreehealthcare · 1 year ago

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Diet and breast cancer

Breast cancer is the most common cancer in women. Breast cancer is diagnosed in 1 in 8 women and 1 in 5 women under the age of 50. If you're postmenopausal or overweight, you're at a higher risk of breast cancer, so you should be at a healthy weight. For that, you need to eat and exercise that is suitable for your condition. Breast cancer diet is suitable. Finally, we discuss the right or wrong of certain foods and their relationship to breast cancer.

The Importance of a Balanced Diet in Breast Cancer Patients

A healthy diet is important for everyone, but if you have breast cancer, you should be more careful about what you eat. Following a balanced diet during and after breast cancer treatment can greatly help improve patients' quality of life and better control the disease.

The foods we mention can form a balanced diet that prevents the development of breast cancer:

A wide variety of colored fruits and vegetables such as garlic, onions, ginger, soybeans, carrots, cabbage, parsley, capsicum, cabbage family and Moringa (especially the roots of this plant, which of course should be consumed under the supervision of a doctor) Foods rich in fiber such as whole grains, legumes and beans Consumption of low-fat milk and dairy products, preferably probiotics Foods rich in vitamin D Foods, especially spices with anti-inflammatory properties, such as turmeric, which prevent the growth of cancerous cells. Green tea with many antioxidant properties instead of caffeinated drinks Use of organic food and not supplements A study of 91,000 women found that following a diet rich in vegetables (about two-thirds) could reduce the risk of developing breast cancer by 15%. Researchers recommend consuming about 8 to 10 servings of fruits and vegetables a day. Among other properties, fruits and vegetables are rich in carotenoids and flavonoids, which have countless medicinal properties. Proper nutrition to prevent breast cancer Research shows that taking into account the diet you must follow with breast cancer and, of course, the aforementioned fruits and vegetables can prevent breast cancer from occurring. dark leafy vegetables paprika tomato eggplant citrus Carrot broccoli onion apple pear peach strawberry Cabbage family Moringa fiber Fiber's positive effects on the digestive system and support of the elimination process help the body rid itself of toxins and their harmful effects.Whole grains and legumes contain antioxidants that help prevent many diseases. It also contains substances. Nutritionists recommend consuming 30-45 grams of fiber daily. obesity Not all fats are bad, researchers say. Fats in processed foods, trans fats in fried foods, and trans fats in some crackers, candies, and donuts can be threatening. Reduce your consumption of saturated fats found in red meats, solid animal oils and hydrogenated oils and replace them with good fats (unsaturated fats) found in olive oil, avocados, nuts and seeds. In addition, omega-3 fatty acids found in cold-water fish such as salmon and herring help prevent breast cancer. foods harmful to breast cancer alcohol There is strong evidence that alcohol consumption may increase the risk of breast cancer. It's estimated that up to 22% of breast cancers can be prevented by stopping drinking. Researchers have found a direct relationship between regular alcohol consumption and breast cancer. Studies show that alcohol can raise estrogen levels and damage cellular DNA. The researchers also said that women who drank alcohol three times a week had a 15% increased risk of developing breast cancer, and this increased risk increased by 10% for each additional day. sugar Studies in mice have shown that high sugar intake causes tumors in the mammary glands, and these tumors tend to metastasize and spread. Other restricted foods: White bread red meat caffeine Estrogen and plant estrogen sources such as soy Sesame cumin linseed licorice Breast Cancer Nutrition Facts and Myths dairy products and breast cancer In most Asian countries, the incidence of breast cancer is lower than in Western countries. One factor that has received a lot of attention is the consumption and type of dairy products. Some believe that the high consumption of milk and dairy products in Western countries contributes to the high incidence of breast cancer, and that the hormones in milk are to blame. However, the eating habits and lifestyles of Asian women are very different from those of the West. But what does science say about this? Scientific studies have yet to confirm strong evidence for an association between dairy products and breast cancer, and have not shown dairy products to be a possible factor in increasing breast cancer risk. Contrary to popular belief, cows in the EU are less likely to develop breast cancer because they are not injected with hormones to produce their milk and because their milk contains lower levels of natural hormones. soybeans and breast cancer As for soy, there are both claims that soy increases the risk of breast cancer and claims that it lowers the risk. But what does science say about this? Soybeans naturally contain plant compounds based on phytoestrogens, which are structurally similar to the female hormone estrogen. Estrogen can attach to cells of some types of breast cancer (ER-positive) and stimulate them to proliferate. High estrogen levels increase the risk of breast cancer. Therefore, it has been suggested that eating soy as part of the diet may increase estrogen levels in humans, but this is not the case. Interestingly, soy phytoestrogens can prevent estrogen from binding to some breast cancer cells, slowing their growth.The largest population survey in the region was conducted in China. A study conducted at the Shanghai Women's Health Research Center examined the health and dietary intake of soy among more than 70,000 Chinese women. Soybean consumption in China is significantly higher than in the United States. Many Chinese are lactose intolerant, so they are fed milk and soy during childhood. In addition, other types of soybeans such as tofu and edamame are part of the traditional Chinese diet. superfoods and breast cancer You may have seen or heard in the media that certain foods rich in the nutrients your body needs may help reduce cancer. And as far as science goes: The term superfood has no legal definition and cannot be used on food stamps.No single food can meet all of the body's needs. Just because a food can kill cancer cells grown in a bowl in a lab doesn't mean eating too much of that food will protect you from cancer. And even with that settling in, we're naturally depriving our bodies of various nutrients and plant compounds. Binge eaters suffer from diets high in calories, saturated fat, sugar, salt, and alcohol, as well as diets that are overweight and unhealthy. You can't fight a low activity diet. Finally, we concluded that overweight, obesity, menopause, physical inactivity, and alcohol consumption are the main factors that increase the risk of breast cancer. nutrition and genetics Foods have been shown to be harmful or beneficial, depending on what mutations are involved in a person's cancer. For example, coffee may benefit people with BRCA1/2 mutations, depending on the genotype of other genes. Patients with BRCA-associated breast cancer respond well to a diet containing resveratrol I3C DIM and genistein. These substances are found in large amounts in superfoods and you can spot these things with the help of a genetic counselor who is also knowledgeable in the field of nutrition so you can determine what kind of mutation you have. And you can get the right diet according to your physical condition. Read the full article

#health #cancer

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amberwellnessgroup · 2 years ago

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Female Hormones: A Balancing Act

Hormone health is an important topic that can affect everyone throughout their lifetime. Some common symptoms of hormone imbalance are irritability, acne, low libido, unwanted hair growth, unwanted weight gain (especially around the abdomen), uterine fibroids, ovarian cysts, recurrent miscarriage, infertility, endometriosis, and some cancers, to name a few. Hormones can be affected by many things such as stress, diet, chemical exposures, and genetics. Having your hormones in balance, can help you be a healthy, happy, adaptable person.

One hormone that gets a lot of attention is estrogen. Estrogen is a lovely hormone that helps regulate the menstrual cycle, is responsible for breast development, and plays a role in bone health, among others. However, because it generally promotes growth in the body, it can be dangerous if left unchecked. One way to balance estrogen dominance is by increasing progesterone. Another way is to limit exposure to xeno- estrogens in your environment. Lastly, adipose (fat) cells also produce estrogen. So, keeping active and maintaining a healthy weight can benefit your hormones greatly.

A piece of the puzzle with estrogen is also its relationship to another well-known hormone, progesterone. Ideally you want to have 100-200 (some argue 300) times more progesterone than estrogen. So, monitoring this ratio can be pivotal in balancing an estrogen dominance picture. We naturally produce less progesterone as we age. However, there are other factors that can deplete progesterone as well. One known correlation is with cortisol, our stress hormone. If we are always under stress and making cortisol, we steal progesterone from the hormone pool (see hormone cascade below) and end up with progesterone insufficiency. Additionally, as women hit menopause their cardiovascular risk goes up, as does men’s risk. Again, referencing the hormone cascade below, you can see the relationship between progesterone and aldosterone. Dr. Lisa also further details this connection with adrenal health and hypertension in the heart health article within this newsletter. Bio-identical progesterone is one possible treatment to get you feeling better while working on the overarching picture of what lead you here. Lastly, progesterone can also play a big role in fertility and pregnancy maintenance. Low progesterone is one of the most common reasons for first trimester miscarriages. It is also a reason for irregular cycle lengths and spotting.

Testosterone is another famous hormone. Testosterone gets blamed for a lot of negative things, but all humans need testosterone to varying degrees. It is responsible for penis and testes development, facial hair growth, it also helps with muscle size, bone strength, and sex drive. High testosterone is commonly a piece of polycystic ovarian syndrome (PCOS) in women. Within the context of PCOS there are some fantastic herbs that can help lower levels, like stinging nettles. Conversely, low testosterone can be related to stress and cortisol production, through the adrenal endocrine pathway. So, using tools to combat stress and promote your parasympathetic nervous system will support hormone balance as well. One of the most accessible ways to do this is through meditation.

Luckily there are many ways to investigate and support your sex hormones and get you back to feeling active, energetic, and engaged. Here are the easy take away points:

Use an app like Think Dirty to decrease xeno-estrogen and carcinogenic chemicals in your home.

Exercise regularly to combat stress, balance testosterone, and to avoid more estrogen producing fat cells.

Avoid animal proteins that aren’t grass-fed, organic, and free of hormones.

Drink green tea to reduce estrogen levels.

If you have known PCOS, drink nettle tea to help reduce testosterone levels.

Partake in restful, restorative activities to reduce cortisol.

To visit more wellness blogs please, click here.

#female hormones

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kabbur28 · 2 years ago

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Breast cancer

Breast cancer is the most common form of cancer among women in industrialised countries, accounting for about 18% of all female cancers. Although mortality is declining in some countries, breast cancer remains the leading cause of death among women aged 35-55 years.

Classical epidemiological studies repeated worldwide have established risk associations with breast cancer. These associations have been bolstered by laboratory tissue and animal studies.

The incidence of breast cancer increases with age. Approximately 50% of breast cancers occur in women aged 50-64 years , and a further 30% occur in women over the age of 70 years. There are also marked geographical variations in incidence; in general, the highest incidences are seen in western countries and the lowest in Asian and African countries. This illustrates the importance of environmental risk factors, as women from low risk countries, such as Japan who emigrate to higher risk countries ultimately develop the higher risk associated with their new country. Genetic factors are also important, however as the natural history of breast cancer appears to vary between populations.

Age is the greatest risk factor for breast cancer. Of the approximately 60% of breast cancers for which identifiable risk factors can be found, age accounts for more than half.

Family History:

The risk of breast cancer is increased 2-3 fold in women with a first degree relative with breast cancer; the risk is also increased, but to a lesser extent, in women with a second degree relative who is affected.

The risk is particularly great if :

The affected relative is on the maternal side of the family

Two first degree relatives are affected

The relative has bilateral breast cancer

The relative’s cancer was diagnosed before the age of 50 years.

Overall about 10-15% of breast cancers are attributable to family history, and half of these can be attributed to specific susceptibility genes

Demography – the risk of breast cancer is increased in women from higher socio economic classes and in women living in urban areas.

The risk of breast cancer is increased in women who being to menstruate at an early age < 12 years or who undergo menopause at a relatively advanced age >55 years. Age at first full term pregnancy appears to be the most important factor in reducing the risk of breast cancer. For women who have their first child before the age of about 25 years, the risk of breast cancer is approximately half that for women who have their first child after 30 years of age, or who remain childless. Similarly, multiparous postmenopausal women have a lower risk of breast cancer than nulliparous women.

Obesity is associated with an increased risk of breast cancer in postmenopausal women. This increased risk may be due to conversion of adrenal androgens to estrogens in adipose tissue. High consumption of animal fats has also been linked to breast cancer.

A recent meta- analysis involving over 150000 women has examined the influence of oral contraceptive use on the risk of breast cancer. The relative risk was slightly increased in women who had used OCs more than 10 years previously. Although the incidence of breast cancer was increased in OC users, the disease mortality remained constant because the cancers tended to be more of a favourable type. This slight increase in risk should, however be viewed in the context of women’s health in general. It is likely that OCs substantially diminish the risk of ovarian and endometrial carcinoma.

They are also highly effective as a form of conception and as a means of relieving menses related morbidity. There is no evidence that current formulations of OCs affect breast cancer risk. However, this will not be known for certain for another 30 years, since the cohort of women who have taken the pill are only now reaching the age at which they are at risk of breast cancer.

The long awaited results of a number of important trials have recently been published, To some extent these studies have confirmed and refined the risk of breast cancer associated with hormone replacement therapy (HRT), but many unanswered questions to be resolved.

The consumption of approximately 15 g or more of alcohol each day increases the risk of breast cancer by about 50%. This may be attributable to reduced hepatic estrogen metabolism. However the increased risk associated with alcohol is small; it has been estimated that if 1000 women over 30 years of age maintained a moderate regular alcohol intake for 2 years one addictional case of breast cancer might develop. This should be set against the potential reduction in ischemic heart disease associated with oderte alcohol consumption and the contribution that alcohol could make to quality of life.

With the rise of modern genetics research, a subcellular and molecular understanding of familial factors in breast cancer is emerging. New technologies have allowed detailed comparisons to be made between the chromosome patterns of normal populations and those at high risk, which meant initially women with very strong family histories.

From these studies, the first genes that were strongly associated with breast cancer were identified notably BRCA1(17q21) and BRCA2 ( 13q14). The risk of breast cancer with these two genes in the absence of family history is high. These genes are implicated in more than 4% of breast cancer and is upto 25% of patients diagnosed before the age of 40 years. They are also linked to ovarian cancers. The breast cancer risk associated with BRCA2 appears less than that with BRCA1, but the presence of the gene mutation carries additional smaller risks of male breast and prostate cancers and perhaps others.

Genes represent predisposition. The internal hormonal and regulatory milieu of the body and life events such as diet, drugs, pregnancies and levels of activity are stimuli in a dynamic homeostatic process. The interaction between predisposition and provocation is when malignancy appears. It is reasonable to hypothesize that genes have an influence beyond susceptibility. Even in these early days there is an evidence that gene expression signatures can predict.

Risk of disease

Relapse and survival risk

Patterns of recurrence

Response to therapy

When these regulatory pathways are better understood, establishing the point at which intervention is necessary will pose a substantial challenge and will profoundly influence our preventive and treatment strategies in the future.

Published Articles by Dr Radheshyam Naik

A Narrative Review of the Association between Pesticides, Organochlorines and Breast Cancer: Current Advances and Research Perspectives

https://clinmedjournals.org/articles/iaphcm/international-archives-of-public-health-and-community-medicine-iaphcm-4-049.php?jid=iaphcm

Genetics and Breast cancer – Oncologist Perspectives

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809842/

Incidental findings in male breast cancer – A genetic counselling approach

https://www.tandfonline.com/doi/abs/10.1080/09723757.2016.11886287

Landscape of clinically actionable mutations in breast cancer ‘A cohort study’

https://pubmed.ncbi.nlm.nih.gov/33099186/

Simulation model for Breast cancer management in India

https://medicalresearchjournal.org/index.php/GJMR/article/view/2029

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guruwithin · 2 years ago

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If you've been afraid to eat soy because of the deluge of misinformation about its health effects, relax and enjoy some tofu. Big animal ag is trying to tell you that the phytoestrogen in soy (and in all plants, actually) will stick you full of estrogen and give you breast cancer. It won't. Phytoestrogen isn't estrogen. Meanwhile, these same folks are promoting cow's milk which is the milk of a mother who has recently given birth and thusly is full of actual estrogen. Meanwhile, this study found that soy actually helps protect your body against breast cancer and other cancers. So enjoy!

Our source for this meme is the Memorial Sloan Kettering Cancer Center

Link to this meme >

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safeenaposts · 2 years ago

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Breast cancer

Classical epidemiological studies repeated worldwide have established risk associations with breast cancer. These associations have been bolstered by laboratory tissue and animal studies.

The incidence of breast cancer increases with age. Approximately 50% of breast cancers occur in women aged 50–64 years , and a further 30% occur in women over the age of 70 years. There are also marked geographical variations in incidence; in general, the highest incidences are seen in western countries and the lowest in Asian and African countries. This illustrates the importance of environmental risk factors, as women from low risk countries, such as Japan who emigrate to higher risk countries ultimately develop the higher risk associated with their new country. Genetic factors are also important, however as the natural history of breast cancer appears to vary between populations.

Age is the greatest risk factor for breast cancer. Of the approximately 60% of breast cancers for which identifiable risk factors can be found, age accounts for more than half.

Family History:

The risk of breast cancer is increased 2–3 fold in women with a first degree relative with breast cancer; the risk is also increased, but to a lesser extent, in women with a second degree relative who is affected.

The risk is particularly great if :

The affected relative is on the maternal side of the family

Two first degree relatives are affected

The relative has bilateral breast cancer

The relative’s cancer was diagnosed before the age of 50 years.

Overall about 10–15% of breast cancers are attributable to family history, and half of these can be attributed to specific susceptibility genes

Demography — the risk of breast cancer is increased in women from higher socio economic classes and in women living in urban areas.

Risk of disease

Relapse and survival risk

Patterns of recurrence

Response to therapy

#ovarian cancers Breast cancer

0 notes

bestcardiologistinranchi · 2 years ago

Text

Types And Risk Factors Of Genital Tract Cancer

Cancer is a disease in which cells in the body grow out of control. When cancer starts in a woman’s genital tract, it is called genital tract cancer. There are three main types of genital tract cancer: uterine cancer (cancer of the uterus), ovarian cancer (cancer of the ovaries) and cervical cancer (cancer of the cervix). Of all genital tract cancers, only cervical cancer has screening tests that can detect this cancer early. This may make the treatment most effective. Since there is no simple and reliable way to screen for any genital tract cancer except cervical cancer, it is especially important to recognize the warning signs and know if there is anything you can do to reduce your risk.

Uterine cancer (cancer of the uterus)

What is uterine cancer?

Uterine cancer is a general term that describes cancer of your uterus, or womb:

Uterine cancer is of two types of cancer: endometrial cancer (more common) and uterine sarcoma.

Endometrial cancer develops in the endometrium, the inner lining of your uterus. It is one of the most common gynecological cancers. This is cancer affecting your reproductive system.

Uterine sarcoma develops in the myometrium, the muscular wall of your uterus. Uterine sarcoma rarely occurs in women.

Who is at higher risk of uterine cancer?

There are several risk factors for endometrial cancer.

Age, lifestyle and family history:

Age: As you age, your chances of developing uterine cancer increase. Most uterine cancers occur after the age of 50.

High animal fat in the diet: A high-fat diet can increase your risk of several cancers, including uterine cancer.

Family history: Some parents carry a genetic mutation (change) for hereditary nonpolyposis colorectal cancer (HNPCC). It increases the risk for several types of cancer, including endometrial cancer.

Other conditions:

Diabetes: This disease is often related to obesity, a cancer risk factor.

Obesity (excess body weight): Some hormones are converted to estrogen by adipose tissue, which increases the risk of uterine cancer.

Diseases of the ovaries: Women who have ovarian tumors have high estrogen levels and low progesterone levels. These hormone changes can increase the risk of uterine cancer.

Menstrual and reproductive history:

Early Menstruation: If you have had your period by the age of 12. The earlier it begins, the higher your risk of uterine cancer may increase. This is because of your uterus’s Exposure to estrogen for more years.

Late menopause: Similarly if menopause starts after 50 years of age, which is after its normal age, then its risk also increases.Your uterus is exposed to estrogen for a long time.

Long menstrual periods.

Not getting pregnant: Women who have not become pregnant have a higher risk because of the increased exposure to estrogen.

Ovarian Cancer (Ovarian Cancer)

What is ovarian cancer?

Cancer develops when cells in your body start growing abnormally. It can happen in any area of the body. When this abnormal growth occurs in the ovaries, it is called ovarian cancer.

Who is at higher risk of ovarian cancer?

Having a family history of ovarian cancer (other women in your family may have the disease) or have a gene mutation (BRCA1 or BRCA 2) be hereditary

never got pregnant

suffering from endometriosis,

suffering from breast, uterine or colorectal cancer

As you get older, your risk of developing ovarian cancer also increases.

Another risk factor is Lynch syndrome. This disorder tends to run in families and may increase the risk of developing colon cancer. Lynch syndrome is associated with several other types of cancer. If you have Lynch syndrome, it may increase your risk of developing other cancers.

Cervical cancer

What is Cervical Cancer?

Cervical cancer begins on the surface of your cervix. This happens when cells in your cervix begin to transform into precancerous cells. Not all precancerous cells will turn into cancer, but finding these problematic cells and treating them before they replace them is important for preventing cervical cancer.

Who is at higher risk of cervical cancer?

In many cases, some risk factors for cervical cancer can be avoided, while others are not within your control. There are some risk factors under your control:

HIV infection: People who are infected with HIV have a higher than-average risk of developing cervical cancer. Birth control pills: There is evidence that long-term use of oral contraceptives may increase your risk of cervical cancer. Multiple children: Having three or more complete pregnancies can increase the risk of developing cervical cancer. Having a weak immune system: Having a weak immune system makes your body unable to fight off infections.

Being diagnosed with cancer can be shocking and scary. Discuss any questions and concerns you may have with your gynecologist. Understand your diagnosis and treatment plan. Having friends and family to support you during this time can help boost your morale in coping with this terrible disease. Diagnosis of this terrible disease and early detection of irregular cells in your genital tract is important for its treatment. You can reduce the chances of having genital tract cancer by regularly visiting your gynaecologist and having safe sex.

TAG- Best Doctor For Pregnancy In Ranchi, Best Pregnancy Hospital In Ranchi,

Best Gynaecologist in Ranchi

#Best Gynaecologist in ranchi #Best Hospital in Ranchi

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prnlive · 2 years ago

Text

Gary Null’s Show Notes

12 20 22 P

If you listen to Gary’s show, you know that he begins with the latest findings in natural approaches to health and nutrition. Here we make some of those findings available each weekday to subscribers to the Gary Null Newsletter.

Purple potato may pack cancer prevention punch - even after cooking

Boosting physical activity and curbing sitting time are highly likely to lower breast cancer risk

How the mind sharpens the senses

Elderberry extract may improve obesity inflammation

First Ground Breaking Study Shows How Rhodiola Rosea Protects People From Viral Infections

How does nature nurture the brain?

Purple potato may pack cancer prevention punch - even after cooking

Pennsylvania State University, September 1, 2022

Anthocyanin compounds found in purple potatoes may help in the prevention of certain types of cancer, even after cooking, say researchers.

The new data, published in the Journal of Nutritional Biochemistry, tested the potential for anthocyanin-containing purple potatoes to block the growth of cancer tumours, even when they have been cooked – after previous research suggested that the polyphenols found in purple potatoes (PP) may help to battle cancer.

Led by Venkata Charepalli from Pennsylvania State University, the team used laboratory tests including in vitro cell line investigations and animal modelling to test how PP impacted colon cancer growth, and in particular, colon cancer stem cells (CSCs), which have previously been suggested to be target by dietary bioactives such as curcumin.

The team reported that their data from in vitro and mouse models suggests that baked purple-fleshed potatoes suppressed the growth of colon cancer tumours by targeting the cancer's stem cells.

They added that there may be several substances in purple potatoes that work simultaneously, and on multiple pathways, to help kill the colon cancer stem cells, including anthocyanins and chlorogenic acid, and resistant starch.

"Our earlier work and other research studies suggest that potatoes, including purple potatoes, contain resistant starch, which serves as a food for the gut bacteria, that the bacteria can covert to beneficial short-chain fatty acids such as butyric acid," said study senior author Professor Jairam Vanamal – also of Penn State. "The butyric acid regulates immune function in the gut, suppresses chronic inflammation and may also help to cause cancer cells to self-destruct."

Boosting physical activity and curbing sitting time are highly likely to lower breast cancer risk

Breast Cancer Association Consortium (UK), September 6, 2022

Boosting physical activity levels and curbing sitting time are highly likely to lower breast cancer risk, finds research designed to strengthen proof of causation and published online in the British Journal of Sports Medicine.

The findings were generally consistent across all types and stages of the disease, reveals the Mendelian randomization study, prompting the researchers to recommend a stronger focus on exercise as a way of warding off breast cancer.

Mendelian randomization is a technique that uses genetic variants as proxies for a particular risk factor—in this case lifelong physical activity levels/sedentary behavior—to obtain genetic evidence in support of a causal relationship.

Observational studies show that physical inactivity and sedentary behavior are linked to higher breast cancer risk, but proving they cause breast cancer is another matter.

The researchers included data from 130,957 women of European ancestry: 69, 838 of them had tumors that had spread locally (invasive); 6667 had tumors that hadn't yet done so (in situ); and a comparison group of 54,452 women didn't have breast cancer.

Researchers estimated overall breast cancer risk, according to whether the women had or hadn't gone through the menopause; and by cancer type (positive for estrogen or progesterone, or HER-2, or positive/negative for all 3 hormones), stage (size and extent of tumor spread), and grade (degree of tumor cell abnormality).

These case-control groups comprised: 23,999 pre/peri-menopausal women with invasive breast cancer and 17,686 women without; 45,839 postmenopausal women with breast cancer and 36,766 without.

Analysis of the data showed that a higher overall level of genetically predicted physical activity was associated with a 41% lower risk of invasive breast cancer, and this was largely irrespective of menopausal status, tumor type, stage, or grade.

Similarly, genetically predicted vigorous physical activity on 3 or more days of the week was associated with a 38% lower risk of breast cancer, compared with no self-reported vigorous activity. These findings were consistent across most of the case groups.

Finally, a greater level of genetically predicted sitting time was associated with a 104% higher risk of triple negative breast cancer. These findings were consistent across hormone-negative tumor types.

How the mind sharpens the senses

Ruhr University Bochum (Germany), August 27, 2022

A study conducted with experienced scholars of Zen-Meditation shows that mental focussing can induce learning mechanisms, similar to physical training. Researchers at the Ruhr-University Bochum and the Ludwig-Maximilians-University München discovered this phenomenon during a scientifically monitored meditation retreat. The journal Scientific Reports, from the makers of Nature, has now published their new findings on the plasticity of the brain.

The participants were all Zen-scholars with many years of meditation practice. The retreat was held in complete silence, with at least eight hours of meditation per day. All participants practiced their familiar meditation, which is characterized by a non-specific monitoring of thoughts and surroundings. Additionally, some participants applied a special finger-meditation for two hours per day, during which they were asked to specifically focus on their right index finger and become aware of spontaneously arising sensory percepts in this finger. Subsequent assessment of the group that practiced finger-meditation showed a significant improvement in the tactile acuity of the right index and middle finger. A control group that had maintained their familiar meditation practice for the whole time, showed no changes in tactile acuity.

In order to assess the sense of touch quantitatively, researchers measured the so-called "two-point discrimination threshold". This marker indicates how far apart two stimuli need to be, in order to be discriminated as two separate sensations. After the finger meditation, the performance improved on average by 17 percent. By comparison, tactile acuity of the visually impaired is 15 to 25 percent above that of typical sighted individuals, because their sense of touch is used so intensively to make up for the reduced visual information. Hence, the changes induced by meditation are comparable to those achieved by intense long-term training.

It is known for long that extensive training induces neuroplasticity, which denotes the ability of the brain to adapt and restructure itself, thereby improving perception and behavior. Recently, the group of neuroscientists of the Neural Plasticity Lab headed by Hubert Dinse has shown that these processes can be initiated even without training by mere exposure to passive stimulation, which was translated only recently into a stimulating glove, which is used as therapeutical intervention in stroke patients. The fact that merely mental states without any physical stimulation can improve perception has now been shown for the first time. "The results of our study challenge what we know about learning mechanisms in the brain. Our concept of neuroplasticity must be extended, because mental activity seems to induce learning effects similar to active stimulation and physical training," Dinse suggests.

Elderberry extract may improve obesity inflammation

University of Connecticut , September 1, 2022

Black elderberry extract may improve obesity-related metabolic disturbances like triglyceride (TAG) levels, inflammation and insulin resistance, research in mice finds.

The researchers from the University of Connecticut in the US said dietary anthocyanins had been shown to reduce inflammation in animal models and to improve obesity-related complications – and black elderberry (Sambucus nigra) was one of the richest sources of these types of flavonoids.

“Overall, black elderberry extract appeared to attenuate systemic inflammation and insulin resistance that occurs with diet-induced obesity in this mouse model, but further research is warranted on black elderberry consumption and effects in humans,” they wrote in the British Journal of Nutrition.

Mice were fed either a low-fat diet, high-fat lard-based diet, a high-fat diet with 0.25% of the extract or a high-fat with 1.25% of the extract for a period of 16 weeks.

The black elderberry extracts amounted to an anthocyanin dose of 20–40 mg per kg of body weight for the 0.25% group and 100–200 mg for the 1.25% group.

After 16 weeks both extract groups had significantly lower liver weights, serum TAG and serum monocyte chemoattractant protein-1 – a serum marker linked to cardiovascular disease and diabetes – compared to the group given the high fat diet alone.

Liver weights were about 13% lower in both extract groups compared to the group given the high fat diet alone.

"Obese individuals have shortened life expectancies; however, they do not typically die of obesity itself but rather obesity-related comorbidities, such as cardiovascular disease, diabetes and certain types of cancers,” they said.

They said inflammation as a result of adipose fat and excessive accumulation of ectopic lipid in tissues was thought to be a key underlying cause of these obesity-related comorbidities, meaning methods that target and lower inflammation could be effective at preventing obesity-related conditions.

First Ground Breaking Study Shows How Rhodiola Rosea Protects People From Viral Infections

Appalachian State University August 26, 2022

Also known as arctic root or golden root, Rhodiola Rosea has already been clinically shown to stimulate serotonin, norepinephrine and dopamine activity, and support healthy neurotransmitter balance, but human trials have now shown the the herb protects against viral infection.

A 2002 review in HerbalGram, the journal of the American Botanical Council, reported that numerous studies of rhodiola in both humans and animals have indicated that it helps prevent fatigue, stress, and the damaging effects of oxygen deprivation. Evidence also suggests that it acts as an antioxidant, enhances immune system function, and can increase sexual energy. Rhodiola's efficacy was confirmed in a 2011 review of 11 placebo-controlled human studies. The reviewers considered studies that all had study designs rated as moderate to good quality, and the analysis of their combined data concluded that rhodiola might have beneficial effects on physical performance, mental performance, and certain mental health conditions.

Nieman’s study "Rhodiola rosea exerts antiviral activity in athletes following a competitive marathon race," which was published July 31 in Frontiers in Nutrition, is the first to show anti-viral activity.

In his study, 48 marathon runners participating in the 2012 Thunder Road Marathon in Charlotte were randomly divided into two groups that ingested either 600 milligrams of Rhodiola rosea or a placebo for a month before the race. Blood samples were collected the day before the marathon and 15 minutes and 1.5 hours post-race. Initial studies found no impact on inflammation and oxidative stress. Additional studies used an in vitro assay to measure the ability of the polyphenolic compounds to protect the cells against Vesicular stomatitis virus. The results demonstrated that Rhodiola rosea delayed viral infection for up to 12 hours after the marathon.

Nieman was the first scientist to find that marathon runners are prone to viral illnesses such as upper respiratory tract infections after competing. This discovery motivated him to research plant-based compounds that could prevent infection and enhance recovery and overall athletic performance.Since Rhodiola rosea administration appears to impact central monoamine levels, it might also provide benefits and be the adaptogen of choice in clinical conditions characterised by an imbalance of central nervous system monoamines. It also suggests that research in areas such as seasonal affective disorder, fibromyalgia, and chronic fatigue syndrome, among others, is warranted.

"Basically after heavy exertion, bacteria and viruses can multiply at a higher rate than normal due to factors in the serum like stress hormones and inflammatory cytokines," Nieman said. "This is why runners are six times more likely to get sick after a marathon. We showed that in those who used Rhodiola rosea the viruses could not multiply, meaning it was acting as a countermeasure."

Rhodiola both stimulates and protects the immune system by reinstating homeostasis (metabolic balance) in the body. It also increases the natural killer cells (NK) in the stomach and spleen. This action may be due to its ability to normalise hormones by modulating the release of glucocorticoid into the body.

How does nature nurture the brain?

Max Planck Society, September 6, 2022

After a 60-minute walk in nature, activity in brain regions involved in stress processing decreases. This is the finding of a recent study by the Lise Meitner Group for Environmental Neuroscience at the Max Planck Institute for Human Development, published in Molecular Psychiatry.

Living in a city is a well-known risk factor for developing a mental disorder, while living close to nature is largely beneficial for mental health and the brain. A central brain region involved in stress processing, the amygdala, has been shown to be less activated during stress in people who live in rural areas, compared to those who live in cities, hinting at the potential benefits of nature. "But so far the hen-and-egg problem could not be disentangled, namely whether nature actually caused the effects in the brain or whether the particular individuals chose to live in rural or urban regions," says Sonja Sudimac, predoctoral fellow in the Lise Meitner Group for Environmental Neuroscience and lead author of the study.

To achieve causal evidence, the researchers from the Lise Meitner Group for Environmental Neuroscience examined brain activity in regions involved in stress processing in 63 healthy volunteers before and after a one-hour walk in Grunewald forest or a shopping street with traffic in Berlin using functional magnetic resonance imaging (fMRI). The results of the study revealed that activity in the amygdala decreased after the walk in nature, suggesting that nature elicits beneficial effects on brain regions related to stress.

"The results support the previously assumed positive relationship between nature and brain health, but this is the first study to prove the causal link. Interestingly, the brain activity after the urban walk in these regions remained stable and did not show increases, which argues against a commonly held view that urban exposure causes additional stress," explains Simone Kühn, head of the Lise Meitner Group for Environmental Neuroscience.

The authors show that nature has a positive impact on brain regions involved in stress processing and that it can already be observed after a one-hour walk. This contributes to the understanding of how our physical living environment affects brain and mental health. Even a short exposure to nature decreases amygdala activity, suggesting that a walk in nature could serve as a preventive measure against developing mental health problems and buffering the potentially disadvantageous impact of the city on the brain.

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