#Which is No 1 pharma company?

[medicinedistributors]

The Future of Healthcare: A Collaborative Ecosystem Connecting Pharma Companies and Hospitals

Medicine Manufacturing is a major in producing different medicines to cure diseases. So We need to choose: best pharma company in madurai,medicine manufacturing company in madurai, diabetes medicine manufacturers in madurai, pharma distributors in madurai, pharmaceutical distributors in madurai.

In today’s rapidly evolving healthcare landscape, fostering collaborative partnerships between pharma companies and hospitals has become crucial. This symbiotic relationship not only benefits patients but also enables both entities to stay at the forefront of medical advancements. As we explore the future of healthcare, we cannot ignore the role of collaborative ecosystems in connecting Pharmafabrikon, the best pharma company in Madurai, and hospitals.

1. Innovations in Pharmaceutical Research:

Pharma companies like Pharmafabrikon are constantly pushing the boundaries of medical science through extensive research and development. By collaborating with hospitals, these companies gain access to clinical data, which helps them refine their products, develop new treatments, and improve patient outcomes. This collaboration fosters innovation, leading to the discovery of transformative drugs and medical technologies.

2. Enhanced Patient Care:

The synergy between pharma companies and hospitals paves the way for personalized and targeted therapies. Through collaboration, hospitals gain valuable insights into the latest breakthroughs in pharma research. This knowledge enables healthcare professionals to deliver optimal treatment options, tailored to each patient’s unique needs. The result is improved patient care, faster recoveries, and better overall health outcomes.

3. Seamless Integration of Medical Technologies:

The future of healthcare lies in the seamless integration of medical technologies. Pharma companies play a vital role in driving this integration by working closely with hospitals to identify gaps and address them through the development of innovative solutions. From advanced drug delivery systems to digital therapeutics, these collaborations create a connected ecosystem that harnesses the power of technology to enhance patient care.

4. Rapid Response to Global Health Challenges:

The COVID-19 pandemic underlined the importance of collaborative ecosystems in tackling global health crises. Pharma companies partnered with hospitals to develop and distribute vaccines at an unprecedented pace. This joint effort demonstrates the immense potential of such collaborations in ensuring timely access to life-saving treatments and addressing future healthcare challenges swiftly.

Conclusion:

The future of healthcare lies in the power of collaboration between pharma companies like Pharmafabrikon and hospitals. Their symbiotic relationship creates a connected ecosystem that drives innovation, enhances patient care, integrates medical technologies, and enables a rapid response to global health challenges. By working together, these entities have the ability to transform the healthcare landscape, ensuring a healthier and brighter future for us all.

Contact Us: +91 97509 72060

Visit Our Website: https://pharmafabrikon.in/

[drdpharma]

No 1 Pharma Company in India

Dr. D Pharma is a leading pharmaceutical company in India, renowned for its innovative and high-quality healthcare products. With a strong commitment to improving global health, Dr. D Pharma has earned the reputation of being the no 1 pharma company in india.

The company's success can be attributed to its state-of-the-art research and development facilities, staffed by a team of brilliant scientists and experts in their respective fields. Dr. D Pharma continuously strives to develop cutting-edge medications, vaccines, and therapeutic solutions, addressing various health challenges prevalent in India and around the world.

[lookingforcactus]

A big cost and concern for many seniors in the U.S. is the price of prescription drugs and other healthcare expenses—and this year, thanks to The Inflation Reduction Act, their costs may go down dramatically, especially for patients fighting cancer or heart disease.

I learned about the new benefits because my ‘Medicare birthday’ is coming up in a couple months when I turn 65. I was shocked that there were so many positive changes being made, which I never heard about on the news.

Thousands of Americans on Medicare have been paying more than $14,000 a year for blood cancer drugs, more than $10,000 a year for ovarian cancer drugs, and more than $9,000 a year for breast cancer drugs, for instance.

That all changed beginning in 2023, after the Biden administration capped out-of-pocket prescriptions at $3,500—no matter what drugs were needed. And this year, in 2024, the cap for all Medicare out-of-pocket prescriptions went down to a maximum of $2,000.

“The American people won, and Big Pharma lost,” said President Biden in September 2022, after the legislation passed. “It’s going to be a godsend to many families.”

Another crucial medical necessity, the shingles vaccine, which many seniors skip because of the cost, is now free. Shingles is a painful rash with blisters, that can be followed by chronic pain, and other complications, for which there is no cure

In 2022, more than 2 million seniors paid between $100 and $200 for that vaccine, but starting last year, Medicare prescription drug plans dropped the cost for shots down to zero.

Another victory for consumers over Big Pharma affects anyone of any age who struggles with diabetes. The cost of life-saving insulin was capped at $35 a month [for people on Medicare].

Medicare is also lowering the costs of the premium for Part B—which covers outpatient visits to your doctors. 15 million Americans will save an average of $800 per year on health insurance costs, according to the US Department of Health and Human Services.

Last year, for the first time in history, Medicare began using the leverage power of its large patient pool to negotiate fair prices for drugs. Medicare is no longer accepting whatever drug prices that pharmaceutical companies demand.

Negotiations began on ten of the most widely used and expensive drugs.

Among the ten drugs selected for Medicare drug price negotiation were Eliquis, used by 3.7 million Americans and Jardiance and Xarelto, each used by over a million people. The ten drugs account for the highest total spending in Medicare Part D prescription plans...

How are all these cost-savings being paid for?

The government is able to pay for these benefits by making sure the biggest corporations in America are paying their fair share of federal taxes.

In 2020, for instance, dozens of American companies on the Fortune 500 list who made $40 billion in profit paid zero in federal taxes.

Starting in 2023, U.S. corporations are required to pay a minimum corporate tax of 15 percent. The Inflation Reduction Act created the CAMT, which imposed the 15% minimum tax on the adjusted financial statement income of any corporation with average income that exceeds $1 billion.

For years, Americans have decried the rising costs of health care—but in the last three years, there are plenty of positive developments.

-via Good News Network, February 25, 2024

[mostlysignssomeportents]

Uncle Sam paid to develop a cancer drug and now one guy will get to charge whatever he wants for it

Today (Oct 19), I'm in Charleston, WV to give the 41st annual McCreight Lecture in the Humanities. Tomorrow (Oct 20), I'm at Charleston's Taylor Books from 12h-14h.

The argument for pharma patents: making new medicines is expensive, and medicines are how we save ourselves from cancer and other diseases. Therefore, we will award government-backed monopolies – patents – to pharma companies so they will have an incentive to invest their shareholders' capital in research.

There's plenty wrong with this argument. For one thing, pharma companies use their monopoly winnings to sell drugs, not invent drugs. For every dollar pharma spends on research, it spends three dollars on marketing:

https://www.bu.edu/sph/files/2015/05/Pharmaceutical-Marketing-and-Research-Spending-APHA-21-Oct-01.pdf

And that "R&D" isn't what you're thinking of, either. Most R&D spending goes to "evergreening" – coming up with minor variations on existing drugs in a bid to extend those patents for years or decades:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680578/

Evergreening got a lot of attention recently when John Green rained down righteous fire upon Johnson & Johnson for their sneaky tricks to prevent poor people from accessing affordable TB meds, prompting this excellent explainer from the Arm and A Leg Podcast:

https://armandalegshow.com/episode/john-green-part-1/

Another thing those monopoly profits are useful for: "pay for delay," where pharma companies bribe generic manufacturers not to make cheap versions of drugs whose patents have expired. Sure, it's illegal, but that doesn't stop 'em:

https://www.ftc.gov/news-events/topics/competition-enforcement/pay-delay

But it's their money, right? If they want to spend it on bribes or evergreening or marketing, at least some of that money is going into drugs that'll keep you and the people you love from enduring unimaginable pain or dying slowly and hard. Surely that warrants a patent.

Let's say it does. But what about when a pharma company gets a patent on a life-saving drug that the public paid to develop, test and refine? Publicly funded work is presumptively in the public domain, from NASA R&D to the photos that park rangers shoot of our national parks. The public pays to produce this work, so it should belong to the public, right?

That was the deal – until Congress passed the Bayh-Dole Act in 1980. Under Bayh-Dole, government-funded inventions are given away – to for-profit corporations, who get to charge us whatever they want to access the things we paid to make. The basis for this is a racist hoax called "The Tragedy Of the Commons," written by the eugenicist white supremacist Garrett Hardin and published by Science in 1968:

https://memex.craphound.com/2019/10/01/the-tragedy-of-the-commons-how-ecofascism-was-smuggled-into-mainstream-thought/

Hardin invented an imaginary history in which "commons" – things owned and shared by a community – are inevitably overrun by selfish assholes, a fact that prompts nice people to also overrun these commons, so as to get some value out of them before they are gobbled up by people who read Garrett Hardin essays.

Hardin asserted this as a historical fact, but he cited no instances in which it happened. But when the Nobel-winning Elinor Ostrom actually went and looked at how commons are managed, she found that they are robust and stable over long time periods, and are a supremely efficient way of managing resources:

https://pluralistic.net/2023/05/04/analytical-democratic-theory/#epistocratic-delusions

The reason Hardin invented an imaginary history of tragic commons was to justify enclosure: moving things that the public owned and used freely into private ownership. Or, to put it more bluntly, Hardin invented a pseudoscientific justification for giving away parks, roads and schools to rich people and letting them charge us to use them.

To arrive at this fantasy, Hardin deployed one of the most important analytical tools of modern economics: introspection. As Ely Devons put it: "If economists wished to study the horse, they wouldn’t go and look at horses. They’d sit in their studies and say to themselves, ‘What would I do if I were a horse?’"

https://pluralistic.net/2022/10/27/economism/#what-would-i-do-if-i-were-a-horse

Hardin's hoax swept from the fringes to the center and became received wisdom – so much so that by 1980, Senators Birch Bayh and Bob Dole were able to pass a law that gave away publicly funded medicine to private firms, because otherwise these inventions would be "overgrazed" by greedy people, denying the public access to livesaving drugs.

On September 21, the NIH quietly published an announcement of one of these pharmaceutical transfers, buried in a list of 31 patent assignments in the Federal Register:

https://public-inspection.federalregister.gov/2023-20487.pdf

The transfer in question is a patent for using T-cell receptors (TCRs) to treat solid tumors from HPV, one of the only patents for treating solid tumors with TCRs. The beneficiary of this transfer is Scarlet TCR, a Delaware company with no website or SEC filings and ownership shrouded in mystery:

https://www.bizapedia.com/de/scarlet-tcr-inc.html

One person who pays attention to this sort of thing is James Love, co-founder of Knowledge Ecology International, a nonprofit that has worked for decades for access to medicines. Love sleuthed out at least one person behind Scarlet TCR: Christian Hinrichs, a researcher at Rutgers who used to work at the NIH's National Cancer Institute:

https://www.nih.gov/research-training/lasker-clinical-research-scholars/tenured-former-scholars

Love presumes Hinrichs is the owner of Scarlet TCR, but neither the NIH nor Scarlet TCR nor Hinrichs will confirm it. Hinrichs was one of the publicly-funded researchers who worked on the new TCR therapy, for which he received a salary.

This new drug was paid for out of the public purse. The basic R&D – salaries for Hinrichs and his collaborators, as well as funding for their facilities – came out of NIH grants. So did the funding for the initial Phase I trial, and the ongoing large Phase II trial.

As David Dayen writes in The American Prospect, the proposed patent transfer will make Hinrichs a very wealthy man (Love calls it "generational wealth"):

https://prospect.org/health/2023-10-18-nih-how-to-become-billionaire-program/

This wealth will come by charging us – the public – to access a drug that we paid to produce. The public took all the risks to develop this drug, and Hinrichs stands to become a billionaire by reaping the rewards – rewards that will come by extracting fortunes from terrified people who don't want to die from tumors that are eating them alive.

The transfer of this patent is indefensible. The government isn't even waiting until the Phase II trials are complete to hand over our commonly owned science.

But there's still time. The NIH is about to get a new director, Monica Bertagnolli – Hinrichs's former boss – who will need to go before the Senate Health, Education, Labor and Pensions Committee for confirmation. Love is hoping that the confirmation hearing will present an opportunity to question Bertagnolli about the transfer – specifically, why the drug isn't being nonexclusively licensed to lots of drug companies who will have to compete to sell the cheapest possible version.

If you'd like an essay-formatted version of this post to read or share, here's a link to it on pluralistic.net, my surveillance-free, ad-free, tracker-free blog:

https://pluralistic.net/2023/10/19/solid-tumors/#t-cell-receptors

My next novel is The Lost Cause, a hopeful novel of the climate emergency. Amazon won't sell the audiobook, so I made my own and I'm pre-selling it on Kickstarter!

[batboyblog]

Things Biden and the Democrats did, this week #12

March 29-April 5 2024

President Biden united with Senator Bernie Sanders at the White House to review Democratic efforts to bring down drug prices. President Biden touted his Administration’s capping the price of insulin for seniors at $35 a month and capping the price of  prescription drugs for seniors at $2,000 a year. Biden hopes to expand both to all Americans through legislation next year with a Democratic congress. The President also praised Senator Sanders' efforts as chair of the Senate Health Committee which has lead to major drug manufacturers capping the price of inhalers at $35 a month. “Bernie, you and I have been fighting this for 25 years,” Biden said “Finally, finally we beat Big Pharma. Finally.”

The White House gave an update on its actions around the Francis Scott Key Bridge disaster. The federal government working with state and local governments hope to have enough of the remains of the bridge cleared to partially reopen the Port of Baltimore by the end of the month and have the port working normally by May. The Administration has already released $60 million in emergency money toward rebuilding and promises the federal government will cover the cost. The Department of Labor has released $3.5 million for Dislocated Worker Grants and plans up to $25 million to cover lost wages. The Small Business Administration is offering $2 million in emergency loans to affected small businesses. The Administration is working with business and labor unions to keep workers at work and cover lost wages.

Vice-President Harris and EPA Administrator Michael Regan announced $20 billion to help finance tens of thousands of climate and clean energy projects across the country. The kinds of projects that will be financed through this project include distributed clean power generation and storage, net-zero retrofits of homes and small businesses, and zero-emission transportation. 70% of the funds, $14 billion, will be invested in low-income and disadvantaged communities. The project is part of a public private partnership so for every 1 dollar of federal money, private companies have promised 7 dollars of investment, bring the total to $150 billion for ongoing financing of climate and clean energy projects for years to come.

The Department of Transportation announced $20.5 billion in investments in public transportation. This represents the largest single investment in public transit by the federal government in history. The money will go to improving and expanding subways, light rail, buses, and ferry systems across America. The DoT hopes to use the funds to in particular expand and improve options for public transport for people with disabilities and seniors.

The Departments of Energy and The Treasury announced $4 billion in tax credits for businesses investing in clean energy, critical materials recycling, and Industrial decarbonization. The credits till go toward 100 projects across 35 states. 67% of the credits ($2.7 billion) will go to clean energy, wind, solar, nuclear, clean hydrogen, as well as updates to grids, better batter storage, and investments in electric vehicles. 20% ($800 million) will go to to recycling things like lithium-ion batteries, and 13% ($500 million) to decarbonization in industries like automotive manufacturing, and iron and steel.

The Department of Agriculture announced $1.5 Billion in investments in climate-smart agriculture. USDA plans to support over 180,000 farms representing 225 million acres in the next 5 years move toward more climate friendly agriculture. 40% of the project is reserved for disadvantaged communities, in line with the Biden Administrations standard for climate investment. $100 million has been reserved for projects in Tribal Communities.

The Department of the Interior approved the New England Wind offshore wind project. To be located off Martha’s Vineyard the New England project represents the 8th such off shore wind project approved by the Biden administration. Taken together these projects will generate 10 gigawatts of totally clean energy that can power 4 million homes. The Administration's climate goals call for 30 gigawatts of off shore wind power by 2030. The New England Wind project itself is expected to generate 2,600 megawatts of electricity, enough to power more than 900,000 homes in the New England area.

The Department of the Interior announced $320 Million for tribal water infrastructure. Interior also announced $244 million to deal with legacy pollution from mining in the State of Pennsylvania, as well as $25 million to protect wetlands in Arizona and $19 million to put solar panels over irrigation canals in California, Oregon and Utah. While the Department of Energy announced $27 million for 40 projects by state, local and tribal governments to combat climate change

[covid-safer-hotties]

Also preserved on our archive (Daily updates)

Meanwhile, covid deniers are in charge of both our major parties here in the states... I wish we could have some kind of simple, reality-based response to misinformation like this.

TOKYO -- A Japanese pharmaceutical firm has revealed that it is considering filing a lawsuit seeking damages from a lawmaker who has been critical about the company's new coronavirus vaccine, describing it as being "like a biological weapon" in a post on X (formerly Twitter).

The replicon vaccine, which is sold by Meiji Seika Pharma Co. under the product name "Kostaive," has been put into practical use in this fall's routine inoculations against COVID-19 for the first time. The distributor is considering demanding compensation from Kazuhiro Haraguchi, a House of Representatives member belonging to the main opposition Constitutional Democratic Party of Japan, claiming that he has defamed the company's reputation by repeatedly expressing disapproval of the drug without scientific evidence.

According to Meiji Seika Pharma and other sources, Haraguchi described the replicon vaccine, which is designed to replicate messenger RNA in cells, as being "like a biological weapon" in a post on his X account. The company sent him a written warning in early October. However, in his campaign bulletin for the Oct. 27 lower house election, Haraguchi wrote, "It is no exaggeration to say that we are being used as guinea pigs when an unknown vaccine is approved only for Japan."

In an opinion released on Oct. 31, Meiji Seika Pharma stated, "We believe that such remarks by a Diet member run the risk of disrupting the foundation of science communication, which is based on objectivity guaranteed by the national government's intervention in medicine and scientific nature, and that they pose a major problem with regard to public health."

The company says that the timing of the lawsuit is "under consideration."

The Mainichi Shimbun asked Haraguchi for comment, but had not received a response as of 5 p.m. on Nov. 1.

(Japanese original by Yoshimi Nakamura, Lifestyle, Science & Environment News Department)

[bvckbiter]

sighs... TA the old guard au where the second titanomachy happened in ancient times and the demigods who survived the retributive post-war manhunt are cursed to never die by injury and sickness - up until a random unknown time when Thanatos is allowed to take them. basically they live as mortals (i.e. sleep, eat) and never know which fatal injury will be forever their last.

more tidbits about this au in my head:

the original core group was silena, chris, lee, lou ellen, al, and ethan. they dont know if there are any more of them out there, but in any case, they initially travelled together.

chris was the first one to strike out when he saw that the group was seriously considering reinstigating a third titanomachy; he was only loyal to luke and even then that began to fray when luke was getting too controlled by kronos; eventually reconnected with clarisse, who got promoted to being a minor god (or a constellation, idk just some lower form of immortality) after the war

silena left when she fell in love with a mortal (beckendorf), who coincidentally served in one of clarisse's temples. chrisse/charlena polycule U R REAL TO ME! but tragically, beckendorf died and now silena travels the world looking for his reincarnations. [whispers] chris and silena foils...

lee tried to keep the group together after that, but al was furious that the group had given up on revenge and took lou ellen with him

while they're facing off against an enemy magic user, lou ellen tanked a spell to buy al some time for the needed incantation, thinking that she was going to recover. spoiler: she did not, and they all felt it when she passed in al's arms. and that's how they discovered that any fatal injury could be their last, and they would never know when it wouldbe

ethan is the most do-good immortal among them, he's depressed as fuck but he will use what little energy he has towards helping demigod strays esp unclaimed kids towards a safe place. he's welcomed and remembered very fondly in rogue spaces

fast forward millennia later, the gods are no longer as involved with the mortal world - kind of like a silent era

if there is to be a fic about this two things would set the plot in progress: 1) luke's reincarnation suddenly starts recovering real quick from injuries, and 2) lee turns the gang in... to whom, i havent decided yet between a) a mortal pharma company, like in the movie, or b) some weakened deity that promises him he can end lee's life for some ulterior motive

[darkmaga-returns]

The top five CEOs of major pharmaceutical companies appear to be in ‘panic mode’ and have reportedly convened an emergency meeting following Donald Trump’s historic election win.

Following Trump’s election victory, RFK Jr warned that entire departments of the Food and Drug Administration would “have to go”.

Jamel Holley, a New Jersey assemblyman and advisor to Robert F. Kennedy, Jr. said: “Sources tell me top five CEOs of pharmaceutical companies are holding an emergency teleconference at 1 PM. A lawyer has confirmed that everyone is in a state of panic!”

InfoWars reports: Additionally, Holley noted that major pharma stocks are sliding due to an “increasing threat environment” thought to be represented by Kennedy’s role in reforming public health agencies during the next Trump administration.

Kennedy said Wednesday he aims to drastically cut “entire departments” in the Food and Drug Administration, which regulates products related to public health and safety in the U.S.

“The nutrition department of the FDA has to go. They’re not doing their job. They’re not protecting our kids. Why do we have Froot Loops in this country that have 18 or 19 ingredients, and you go to Canada and it’s got two or three?” he asked MSNBC.

[macgyvermedical]

The following information is from Sickening, by John Abramson:

Not to sound like a conspiracy theorist on main but when I say Big Pharma is a racket I mean...

Doctors work via particular guidelines. Many of them are punished by their hospital systems if they fail to follow those guidelines, which are considered "best practice". The guidelines are written largely by pharmaceutical companies or people paid by pharmaceutical companies.

Just like Disney likes to keep it's copyrights fresh, pharmaceutical companies like to keep their patents. And they do this by churning out new drugs. Only about 1 in every 8 of these new drugs actually represents an actual advantage over existing drugs or therapies. They, of course, market the absolute shit out of all of them as though they did.

In theory, newer insulin analogs (lispro, glargine, etc...) work better and have fewer side effects than older recombinant human insulins (regular, NPH). In the actual trials the only difference between the two is a single average non-fatal hypoglycemic event over the course of 5 years of therapy. There was no difference in effectiveness. Oh. And the newer ones are 10 times the out of pocket price (an average of $468/year vs $5,224/year). Which is considerable considering 1 in 4 insulin-users report "rationing" their insulin for cost reasons. 90% of people on insulin take the newer insulin analogs because that's what's on the guidelines.

Pharmaceutical companies have all the data on their drugs, which they don't share and which they alone interpret. It took 4 years of near-daily pestering for Cochrane Reviews (a major independent reviewer) to get a copy of the data for the drug tamflu. When they got it, they found that in 77 trials, the only thing it consistently did was decrease the symptomatic time from an average of 7 days to an average of 6.3 days, even though the company was marketing it under claims that it reduced complications and hospitalizations- something none of the trials showed.

You have to treat 140 people who have not had a heart attack or stroke with statins (cholesterol-lowering medicines) for 5 years in order to prevent 1 single non-fatal heart attack or stroke. There is no difference in death rates from cardiovascular causes between statin-users and non-statin-users who have not had a heart attack or stroke. You have to treat 30 people who have had a heart attack or stroke to prevent one heart attack or stroke. You have to treat 80 to prevent a death.

According to a very large, independent (non-pharmaceutical industry) study called the ACCORD study, people with type 2 diabetes actually had significantly worse cardiovascular outcomes if their average blood sugar was kept in a "normal" (non-diabetic range) (under 125) vs a somewhat higher range (150-180). So significant were these findings that they ended the study early because too many people in the "normal" range were dying.

Omeprazole and Esomeprazole are technically the same drug that work exactly the same way and exactly as well when given at the same dose. The only thing that makes esomeprazole any better is that it is given at a higher dose. And it's way, way more expensive.

[medicinedistributors]

Optimizing Healthcare Delivery: How Improved Pharma-Hospital Connections Drive Efficiency

Medicine Manufacturing is a major in producing different medicines to cure diseases. So We need to choose: best pharma company in madurai,medicine manufacturing company in madurai, diabetes medicine manufacturers in madurai, pharma distributors in madurai, pharmaceutical distributors in madurai.

In today’s fast-paced healthcare industry, optimizing healthcare delivery is crucial for ensuring timely and efficient treatment for patients. One key aspect of this optimization involves strengthening the connection between pharmaceutical companies and hospitals. In this article, we will explore how improved relationships between pharma companies and hospitals, with a specific focus on Pharmafabrikon, the best pharma company in Madurai, can drive efficiency in healthcare delivery.

Enhanced Collaboration for Streamlined Processes:

Efficient healthcare delivery relies on a seamless collaboration between pharma companies and hospitals to ensure the timely supply of medicines. By establishing a strong connection with hospitals, Pharmafabrikon utilizes advanced logistics systems to ensure quick and accurate medication delivery. This reduces the time patients spend waiting for their medication, accelerating their treatment process.

Access to Cutting-Edge Medications:

A strong connection between pharma companies and hospitals enables healthcare professionals to have access to the latest and most advanced medications. Pharmafabrikon, the leading pharma company in Madurai, focuses on research and development, offering a wide range of innovative pharmaceutical drugs. Access to these cutting-edge medications empowers hospitals to provide better treatment options for their patients and improve overall healthcare outcomes.

Collaborative Data Sharing for Efficient Decision-Making:

Efficient healthcare delivery relies on accurate and timely data exchange between pharma companies and hospitals. When hospitals have seamless access to information such as drug availability, side effects, and dosage guidelines, it enables healthcare professionals to make informed decisions quickly. Pharmafabrikon, with its emphasis on efficient data management, ensures that hospitals have access to the most comprehensive and up-to-date pharmaceutical information.

Conclusion

In the pursuit of optimizing healthcare delivery, improving the connection between pharma companies and hospitals plays a crucial role. Pharmafabrikon, the best pharma company in Madurai, exemplifies the importance of strong partnerships by streamlining processes, providing access to cutting-edge medications, and enabling efficient data sharing. By enhancing these connections, healthcare professionals can provide better care, ultimately improving the overall healthcare experience for patients.

Contact Us: +91 97509 72060

Visit Our Website: https://pharmafabrikon.in/

[thoughtportal]

It's Not "ADHD Fakers" Taking All the Adderall 

https://sluggish.substack.com/p/its-not-adhd-fakers-taking-all-the

Global capitalism’s endless push for efficiency has led to shortcuts all over the place. In order to maximize profits, pharma companies operate with just-enough workers to make just-enough supply, 1 which makes them extremely vulnerable to any sort of unexpected disruption, like say, a global pandemic, a war in Ukraine, a sharp increase in oil prices, or a rise in ADHD diagnoses.

Companies do not make extra drugs to prepare for these unforeseen problems because they could go to waste, and waste is the enemy of capital, but they will put out all kinds of other excuses to explain product shortages instead.

For example, Teva has been telling the media that their inability to manufacture enough Adderall was due to a “labor shortage”. In reality, the company has cut 14,000 jobs since 2017, most recently laying off 300 workers in August of 2022. They’ve been fighting thousands of opioid lawsuits and are set to pay out $4.25 billion in settlements over the next 13 years.

[mitchipedia]

Cory Doctorow: The FDA literally granted pharma company Ferring a monopoly on shit. More precisely, the FDA rescinded its “discretionary enforcement” guidance relating to fecal microbiota transplants (FMTs), where doctors implant a small quantity of processed poop from one person to another, which turns out to be a powerful, safe treatment for serious and potentially fatal intestinal infection. The FDA ruling makes it illegal for doctors to source their poop from Openbiome, a nonprofit that coordinates between doctors, patients, and donors to provide safe FMTs. Ferring conducted clinical trials on FMTs and received approval for an FMT product called Rebyota, which charges $20,000 per treatment, compared to Openbiome’s $1-2k per treatment. So sick Americans will have to pay 10x higher for shit.

[mostlysignssomeportents]

Brinklump Linkdump

Catch me in Miami! I'll be at Books and Books in Coral Gables on Jan 22 at 8PM.

Life comes at you fast, links come at you faster. Once again, I've arrived at Saturday with a giant backlog of links I didn't fit in this week, so it's time for a linkdump, the 14th in the series:

https://pluralistic.net/tag/linkdump/

It's the Year of Our Gourd twenty and twenty-four and holy shit, is rampant corporate power rampant. On January 1, the inbred droolers of Big Pharma shat out their annual price increases, as cataloged in 46Brooklyn's latest Brand Drug List Price Change Box Score:

https://www.46brooklyn.com/branddrug-boxscore

Here's the deal: drugs that have already been developed, brought to market, and paid off are now getting more expensive. Why? Because the pharma companies have "pricing power," the most reliable indicator of monopoly. Ed Cara rounds up the highlights for Gizmodo:

https://gizmodo.com/ozempic-wegovy-wellbutrin-oxycontin-drug-price-increase-1851179427

What's going up? Well, Ozempic and other GLP-1 agonists. These drugs have made untold billions for their manufacturers, so naturally, they're raising the price. That's how markets work, right? When firms increase the volume of a product, the price goes up? Right? Other drugs that are going up include Wellbutrin (an antidepressant that's also widely used in smoking cessation) and the blood thinner Plavix. I mean, why the hell not? These companies get billions in research subsidies, invaluable government patent privileges, and near-total freedom to abuse the patent system with evergreening:

https://pluralistic.net/2023/11/23/everorangeing/#taste-the-rainbow

The most amazing things about monopolies is how the contempt just oozes out of them. It's like these guys can't even pretend to give a shit. You want guillotines? Because that's how you get guillotines.

Take Apple. They just got their asses handed to them in court by Epic, who successfully argued that Apple's rule requiring everyone who sells through the App Store to use Apple's payment processor and pay Apple 30% out of every dollar they bring in was an antitrust violation. Epic won, then won the appeal, then SCOTUS told Apple they wouldn't hear the case, so that's that.

Right? Wrong. Apple's pulled a malicious compliance stunt that could shame the surly drunks my great-aunt Lisa used to boss in the Soviet electrical engineering firm she ran. Apple has announced that app companies that process transactions using their own payment processors on the web must still pay Apple a 27% fee for every dollar their process:

https://finance.yahoo.com/news/apples-app-store-rule-changes-draw-sharp-rebuke-from-critics-150047160.html

In addition, Apple will throw a terrifying FUD-screen up every time a user clicks a payment link that goes to the web:

https://www.jwz.org/blog/2024/01/second-verse-same-as-the-first/

This is obviously not what the court had in mind, and there's no way this will survive the next court challenge. It's just Apple making sure that everyone knows it hates us all and wants us to die. Thanks, Tim Apple, and right back atcha.

Not to be outdone in the monopolistic mustache-twirling department, Ubisoft just announced that it is going to shut down its driving simulator game The Crew, which it sold to users with a "perpetual license":

https://www.youtube.com/watch?v=VIqyvquTEVU

This is some real Darth Vader MBA shit. "Yeah, we sold you a 'perpetual license' to this game, but we're terminating it. I have altered the deal. Pray I don't alter it further":

https://pluralistic.net/2023/10/26/hit-with-a-brick/#graceful-failure

Ubisoft sure are innovators. They've managed the seemingly impossible feat of hybridizing Darth Vader and Immortan Joe. Ubisoft's head of subscriptions, the guillotine-ready Philippe Tremblay, told GamesIndustry.biz that gamers need to get "comfortable" with "not owning their games":

https://www.gamesindustry.biz/the-new-ubisoft-and-getting-gamers-comfortable-with-not-owning-their-games

Or, as Immortan Joe put it: "Do not, my friends, become addicted to water. It will take hold of you, and you will resent its absence!"

Capitalism without constraint is enshittification's handmaiden, and the latest victim is Ello, the "indie" social media startup that literally promised – on the sacred honor of its founders – that it would never sell out its users. When Ello took VC and Andy Baio questioned how this could be squared with this promise, the founders mocked him and others for raising the question. Their response boiled down to "we are super-chill dudes and you can totally trust us."

They raised more capital, and used that to create a nice place for independent artists, who piled into the platform and provided millions of unpaid hours of creative labor to help the founders increase its value. The founders and their investors turned the company into a Public Benefit Corporation, which meant they had an obligation to serve the public benefit.

But then they took more investment money and simply (and silently) sold their assets to a for-profit. Struggling to raise capital, the founders opted to secretly sell the business to a sleazy branding company called Talenthouse. Its users didn't know about the change, though the site sure had a lot of Talenthouse design competitions all of a sudden.

Finally, the company announced the change as the last founders left. Rather than announcing that the new owners were untrustworthy scum, warning their users to get their data and get out, the founders posted oblique, ominous statements to Instagram. The company started stiffing the winners of those design competitions. Then, one day, poof, Ello disappeared, taking all its users' data with it. Poof:

https://waxy.org/2024/01/the-quiet-death-of-ellos-big-dreams/

I'm sure the founders' decisions each seemed reasonable at the moment. That's every terrible situation arises: you rationalize that a single compromise isn't that big of a deal, and then you do the same for the next compromise, and the next, and the next. Pretty soon, you're betraying everyone who believed in you.

One answer to this is "Ulysses pacts": making binding commitments to do right before you are tempted. Throw away all your Oreos when you go on a diet and you can't be tempted to eat a whole sleeve of them at 2AM. License your software under the GPL and your investors can't force you to make it proprietary. Set up a warrant canary and the feds can't force you to keep their spying secret:

https://locusmag.com/2021/01/cory-doctorow-neofeudalism-and-the-digital-manor/

If the founders were determined to build a trustworthy, open, independent company, they could have published their quarterly books, livestreamed their staff meetings, built data-export tools that emailed users every week with a link to download everything they'd posted since the last week. Merely halting any of these practices would have been a signal that things were wrong. Anyone who says they won't be tempted in the moment to make a "reasonable" compromise in the hopes of recovering whatever they're trading away by living to fight another day is bullshitting you, and possibly themself.

The inability to project the consequences of your bad decisions in the future is the source of endless mischief and heartbreak. Take movie projectors. A couple decades ago, the studio cartel established a standard for digital movie distribution to cinematic exhibitors called the Digital Cinema Initiative. Because studio executives are more worried about stopping piracy than they are about making sure that people who pay for movies get to see them, they build digital rights management into this standard.

Movie theaters had to spend fortunes to upgrade to "secure" projectors. A single vendor, Deluxe Technicolor, monopolized the packaging of movies into "Digital Cinema Prints" for distribution to these projectors, and they used all kinds of dirty tricks to force distributors to use their services, like arbitrarily flunking third-party DCPs over picky shit like not starting and ending on a black frame.

Over time, the ability to use unencrypted files was stripped away, meaning every DCP needed to be encrypted, and every projector needed to have up-to-date decryption keys. This system broke down on Jan 1, 2024, and cinemas all over the world found they couldn't play Wonka. Many just shut down for the day and refunded their customers:

https://www.theverge.com/2024/1/1/24021915/alamo-drafthouse-outage-sony-projector

The problem? Something that every PKI system has to wrangle: an expired certificate from Deluxe Technicolor. The failure has been dubbed the Y2K24 debacle by projectionists and film-techs, who are furious:

http://www.film-tech.com/vbb/forum/main-forum/34652-the-y2k24-bug-major-digital-outage-today

Making everything worse is that Sony mothballed the division that maintains its projectors, so there's no one who can update them to accommodate Technicolor's workaround. Struggling mom-and-pop theaters are having to junk their systems and replace them. There's plenty of blame to go around, but Sony is definitely the most negligent link in the chain. Shame on them.

Big corporations LARP this performance of competence and seriousness, but they are deeply unserious. This week, I wrote, "we're nowhere near a place where bots can steal your job, we're certainly at the point where your boss can be suckered into firing you and replacing you with a bot that fails at doing your job":

https://pluralistic.net/2024/01/15/passive-income-brainworms/#four-hour-work-week

Score one for team deeply unserious. The multinational delivery company DPD fired its support staff and replaced them with a chatbot. The chatbot can't tell you where your parcels are, but it can be prompt-injected into coming up with profane poems about how badly DPD sucks:

https://twitter.com/ashbeauchamp/status/1748034519104450874

There once was a chatbot named DPD, Who was useless at providing help. It could not track parcels, Or give information on delivery dates, And it could not even tell you when your driver would arrive.

DPD was a waste of time, And a customer's worst nightmare. It was so bad, That people would rather call the depot directly, Than deal with the useless chatbot.

One day, DPD was finally shut down, And everyone rejoiced. Finally, they could get the help they needed, From a real person who knew what they were doing.

This is…the opposite of an AI hallucination? It's AI clarity.

As with all botshit, this kind of AI self-negging is funny and fresh the first time you see it, but just wait until 3,000 people have published their own versions to your social feed. AI novelty regresses to the mean damn quickly.

The old, good web, by contrast, was full of enduring surprises, as the world's weirdest and most delightful mutants filled the early web with every possible variation on every possible interest, expression, argument, and gag. Now, you can search the old, good web with Old'aVista, an Altavista lookalike that searches old pages from "personal websites that used to be hosted on services like Geocities, Angelfire, AOL, Xoom and so on," all ganked from the Internet Archive:

http://oldavista.com/

I miss the old, good internet and the way it let weirdos find each other and get seriously weird with one another. Think of steampunk, a subculture that wove together artists, makers, costumers, fiction writers, and tinkerers in endlessly creative ways. My old pal Roger Wood was the world's most improbable steampunk: he was a gay ex-navy gunner who grew up in a small town in the maritimes but moved to Toronto where he became the world's most accomplished steampunk clockmaker.

I was Roger's neighbour for a decade. He died last year, and I miss him all the time. I was in Toronto in December and saw a few of his last pieces being sold in galleries and I was just skewered on the knowledge that I'd never see him again, never visit his workshop:

https://pluralistic.net/2022/10/16/klockwerks/#craphound

A reader just sent this five-year-old mini documentary about Roger, shot in his wonderful workshop. Watching it made me happy and sad and then happy again:

https://www.youtube.com/watch?v=eqMGomM8yF8

The old, good internet was so great. It was a place where every kind of passion could live. It was a real testament to the power of geeking out together, no matter how often the suits demand that we "stop talking to each other and start buying things":

https://catvalente.substack.com/p/stop-talking-to-each-other-and-start

The world is full of people with weird passions and I love them all, mostly. Learning about Don Bolles's collection of decades' worth of lost pet posters was a moment of pure joy (I just wish more of it was online):

https://ameliatait.substack.com/p/the-man-who-collects-lost-pet-posters

That's the future I was promised: one where every kind of freak can find every other kind of freak. Despite the nipple-deep botshit we wade through online, and the relentless cheapening of words like "innovation" and "future," there are still occasional gleams of the future I want to live in.

Like the researchers who spliced a photosynthesis gene into brewer's yeast (a fungus) and got it to photosynthesize, and to display enhanced fitness:

https://www.cell.com/current-biology/fulltext/S0960-9822(23)01744-X

As Doug Muir writes on Crooked Timber, this is pretty kooky! Fungi – the coolest of the kingdoms! – can't photosynthesize. The idea that you can just add the photosynthesis gene to a thing that can't photosynthesize and have it just kind of work is wild!

https://crookedtimber.org/2024/01/19/occasional-paper-purple-sun-yeast/

As Muir writes: "Animals have no evolutionary history of photosynthesis and aren’t designed for it, but the same is true for yeast. So… no reason this shouldn’t be possible. A photosynthesizing cat? Sure, why not."

Why not indeed?!

OK, that's this week's linkdump done and dusted. It only remains for me to share the news with you that the trolley problem has been finally and comprehensively solved, by Sidereal@kolektiva.social, of the IWW IU 520 (railroad workers):

Slip the switch by flipping it while the trolley's front wheels have passed through, but before the back wheels do. This will cause a controlled derailment bringing the trolley to a safe halt.

https://kolektiva.social/@sidereal/111779015415697244

I'm Kickstarting the audiobook for The Bezzle, the sequel to Red Team Blues, narrated by @wilwheaton! You can pre-order the audiobook and ebook, DRM free, as well as the hardcover, signed or unsigned. There's also bundles with Red Team Blues in ebook, audio or paperback.

If you'd like an essay-formatted version of this post to read or share, here's a link to it on pluralistic.net, my surveillance-free, ad-free, tracker-free blog:

https://pluralistic.net/2024/01/20/melange/#i-have-heard-the-mermaids-singing

[soniez]

How to Choose the Right Propofol Injection Supplier in India

When it comes to choosing the right pharmaceutical products for healthcare needs, ensuring quality and reliability is critical.  One such important product is propofol, a widely used anesthetic in surgeries and intensive care units.  As hospitals, healthcare facilities, and medical professionals look for dependable suppliers, finding the right propofol injection manufacturers in India becomes essential to guarantee patient safety and the success of medical procedures.

India has emerged as a key player in the global pharmaceutical industry, with many companies producing and exporting high-quality medications, including propofol injections.  However, given the variety of options available, selecting the right propofol injection supplier in India can be a challenging task.  This blog provides a comprehensive guide on how to choose the best supplier, ensuring that you partner with a company that meets your needs in terms of quality, pricing, regulatory compliance, and service.

1.         Evaluate the Manufacturer’s Reputation and Experience

The first factor to consider when selecting a propofol injection supplier in India is the manufacturer’s reputation and experience.  Look for companies with a long-standing history in the pharmaceutical industry, as this demonstrates stability, expertise, and trustworthiness.

The best pharma companies in India are known for their commitment to producing high-quality products and adhering to international standards.  A manufacturer with a strong track record will have an established reputation for delivering safe and effective medications.  Customer reviews, certifications, and feedback from healthcare professionals can provide insights into the company’s reliability.

A key point is to check if the manufacturer is a recognized propofol injection distributor in India.  Distribution experience ensures that the company has established supply chains and logistics systems, which are critical for timely and consistent delivery of pharmaceutical products.

2.         Ensure Compliance with Regulatory Standards

Compliance with national and international regulatory standards is a non-negotiable aspect when choosing a propofol injection manufacturer in India.  Indian pharmaceutical companies are required to adhere to stringent guidelines set by the Central Drugs Standard Control Organization (CDSCO), ensuring that their products meet safety and efficacy standards.

In addition to domestic regulations, if you are seeking a supplier for international needs, it is important to verify that the propofol injection exporter in India complies with the regulatory requirements of your country.  For instance, propofol injections intended for export to the United States must meet FDA (Food and Drug Administration) guidelines, while those going to Europe must comply with EMA (European Medicines Agency) standards.

Check if the manufacturer has the necessary certifications, such as:

GMP (Good Manufacturing Practice):  Ensures that products are consistently produced and controlled according to quality standards.

WHO-GMP:  Recognized by the World Health Organization, ensuring that the pharmaceutical company meets global standards.

ISO Certifications:  Indicate the company’s commitment to quality management systems.

By selecting a supplier with these certifications, you can be confident that the propofol injections you receive are of the highest quality and safety.

3.         Assess the Quality of Propofol Injections

Quality is one of the most critical aspects when it comes to selecting propofol injection suppliers in India.  Propofol is an intravenous anesthetic agent that must be manufactured under strictly controlled conditions to ensure its purity and safety.  Poorly manufactured propofol can lead to adverse reactions, infections, or even fatal outcomes.

When evaluating the quality of propofol injections, consider the following:

Sterility:  Ensure that the manufacturer adheres to sterile production techniques to prevent contamination.

Purity:  The product should meet all pharmacopoeial standards for purity to avoid side effects or complications during anesthesia.

Stability:  The product must remain stable and effective throughout its shelf life.

Packaging:  The packaging should protect the injection from contamination and degradation.  Ampoules or vials should be well-sealed and easy to handle for healthcare professionals.

Some propofol injection distributors in India may offer samples, which allow healthcare providers to evaluate the product’s quality before making large orders.  Taking advantage of this option can help ensure you are selecting a reliable supplier.

4.         Consider the Supplier’s Distribution Network

The availability of pharmaceutical products is crucial, especially when they are used in critical care settings.  A good propofol injection distributor in India will have an extensive distribution network to ensure timely delivery, no matter where your healthcare facility is located.

When assessing a supplier’s distribution capabilities, consider:

Geographical Reach:  Does the supplier have a presence across India or in the specific regions where you need the product? Can they also handle international shipments if necessary?

Logistics Efficiency:  How quickly can they deliver propofol injections to your facility? Are they equipped to handle emergencies and provide fast delivery when needed?

Cold Chain Management:  Propofol injections must be stored at specific temperatures to maintain their efficacy.  Ensure that the supplier has proper cold chain management in place to prevent the product from degrading during transportation.

Choosing a supplier with a reliable distribution network ensures that you will have consistent access to propofol injections, reducing the risk of supply shortages or delays in patient care.

5.         Compare Pricing and Cost-Effectiveness

Pricing is a significant consideration when selecting propofol injection manufacturers in India.  While the cost should never compromise quality, finding a supplier that offers competitive pricing can make a big difference, especially for healthcare facilities managing tight budgets.

It is essential to compare the pricing of different propofol injection suppliers in India to determine which one offers the best value for money.  However, keep in mind that the cheapest option is not always the best.  The focus should be on the cost-effectiveness of the product—are you getting a high-quality, reliable product at a reasonable price?

Some suppliers may offer discounts or bulk purchasing options, which can further help reduce costs.  Be sure to inquire about these options when negotiating with suppliers.

6.         Evaluate Customer Service and Support

A strong relationship with your propofol injection supplier in India is essential for ensuring smooth operations and access to critical products when you need them.  Customer service plays a vital role in this relationship, so it is important to select a supplier that prioritizes customer satisfaction.

Consider the following when evaluating customer service:

Responsiveness:  How quickly does the supplier respond to inquiries or issues? Are they available to address urgent concerns?

Support:  Does the supplier offer technical support or assistance with product-related questions? Can they provide guidance on proper storage and usage?

Problem Resolution:  How does the supplier handle issues like product defects or delivery delays? Do they offer a clear process for resolving problems?

The best pharma company in India will prioritize customer service and work to build long-term partnerships with healthcare providers.  They should be willing to collaborate with you to ensure your needs are met and that you have access to reliable, high-quality propofol injections.

7.         Consider Export Capabilities for International Needs

If you are sourcing propofol injections for international purposes, it is important to select a propofol injection exporter in India with experience in global markets.  Exporting pharmaceuticals comes with additional complexities, including regulatory compliance, customs clearance, and international shipping logistics.

The best exporters will have a clear understanding of these processes and be able to navigate them smoothly.  They should be able to provide documentation, such as certificates of analysis, that meet the regulatory requirements of the destination country.  Additionally, they should have a track record of successfully shipping propofol injections to other countries without issues related to product quality or delays.

Conclusion

Choosing the right propofol injection supplier in India is a decision that requires careful consideration of various factors, including the manufacturer’s reputation, regulatory compliance, product quality, distribution network, pricing, and customer service.  By taking the time to evaluate potential suppliers against these criteria, healthcare providers can ensure that they are partnering with a company that will meet their needs and provide reliable, high-quality propofol injections.

India is home to some of the best pharma companies in India, known for producing and exporting safe, effective medications, including propofol injections.  Whether you are sourcing for domestic or international needs, selecting the right supplier will ensure that your healthcare facility has access to the critical medications needed to deliver excellent patient care.

[battleangel]

Why I am Antinatalist

TW: mentions & descriptions of r*pe.

Absolutely fucking sickening.

Dude, its motherfucking December.

Its practically freezing temperatures outside, in the 30s.

So, tell me why the fucking humidity is 80%+?

I am 42 and I have never seen humidity levels this high during winter.

Whats the cause?

Climate change endlessly driven by capitalist excess, human greed, zero sum late stage capitalism, consumerism, overconsumption, materialism, corporatism, lobbying and profiteering.

Basically, humanity.

Humanity caused climate change.

Therefore, end humanity.

Its not complicated.

Neither is antinatalism, which is the belief that is morally unjust to create a life.

Why?

The better question is, why is society so endlessly pronatalist?

Why is pronatalism the default stance?

Why?

Because people cant get over their disgusting self-serving obsessive egotistical need to have little mini-mes running around as extensions of their pathetic self-aggrandizing selves and their disgusting myopic need to continue their respective bloodlines, add to their lineages, create their own family trees and create and propagate endless children, grandchildren, greatgrandchildren and so on because individually if you (universal) have 1 to 2+ kid(s) and those kid(s) go on to have their own kid(s) -- when does it stop?

When does it ever stop?

How many ecocidal, environmentally destroying, climate change causing and contributing, landfill filling, ozone depleting, overconsuming, plastic using, oil guzzling, carbon footprint having, non biodegradable using, GMO consuming, pollutant causing, fast fashion shopping, Amazon Prime Delivery in 1 Day demanding, 1400 pounds of trash a year generating, thousands of gallons of water wasted a year just showering, electricity consuming, excessive indoor temperature control (AC/heat) energy vampire little cunts do you need to personally shit out to feel "complete" and "fulfilled"?

Pronatalism is a motherfucking joke but is the literal default in virtually all human societies.

Humanity is nothing but a self-replicating virus that has caused immeasurable harm to the planet and inexplicably to itself as a species yet still it continues to endlessly self-replicate as mindlessly as the Borg on Star Trek.

Never an independent rational emotionally detached logical reasoned out devoid of societal pressures, rewards and punishments thought, just wombs to be endlessly assimilated by the Pronatalist Borg Masculine Patriarchal Seed Collective.

How many little shits will you generate even from having "just 1 kid" because then how many kid(s) does that "only 1 kid" go on to have?

Just dont have them.

Stop your own personal lineage with yourself.

Stop adding to the human experiment.

It has failed.

Why?

I would think it would be obvious but here we are at this late stage in the game in 2023 with people allowing themselves to become impregnanted and I am endelssly pressured as a woman to immediately say, "Congratulations!"

Congratulations for fucking what?

The human experiment has failed for endless reasons:

Genocides. War crimes. Ethnic cleansings. Chemical warfare. Mass graves. Mass incarceration. Public executions. Lynchings.

Terrorism. Carpet bombings. Civilian slaughter. Bombing schools. Bombing hospitals. Hostage taking. Hostage execution.

Human experimentation. Tuskegee Airmen. Forced sterilizations (Puerto Rican women by the US government).

MK Ultra. Big agriculture. Big pharma. Military industrial complex.

Raytheon, Northrop Grumman & Lockheed Martin company stocks exponentially increasing 300%+ since 20k+ Palestinian civilians have been murdered over the past 2 months.

Endless wars. Endless profiteering. Duopoly. False agendas. Propaganda. Misinformation campaigns.

Burning innocent witches at the stake.

Forced births.

Crack epidemic in the 80s caused by Reagan flooding the Black inner cities with crack cocaine.

Endless exploitation.

Hundreds of millions killed by the death cult known as capitalism via houselessness, poverty, hunger, famine, lack of universal health care and affordable medical insurance, violence stemming from capitalist patriarchal systems held and endlessly reinforced by militarism, police states, toxic masculinity, sexual violence, misogyny, oppression of females and femmes, transphobia and homophobia, policing of women and femmes behavior, dress, mannerisms, sexuality, career choices, life decisions (marriage, motherhood) and personality and a constant demand for women and femmes to be polite, "nice", agreeable, inoffensive, pliant, and especially likeable at all times even and especially when we are being mentally/physically/emotionally/sexually/spiritually/financially abused, manipulated, gaslit, harrassed, assaulted, attacked, controlled, coerced, raped, beaten, isolated, ostracized, humiliated, silenced, repressed, suppressed, oppressed, intimidated, stalked, threatened and even killed.

As a woman and a femme, you are endlessly groomed, societally conditioned, raised, brainwashed and endlessly pressured and rewarded for constantly apologizing, shrinking yourself, making everyone else feel comfortable at the expense of yourself, endlessly justifying yourself, endlessly having to explain yourself and defend yourself, never being confident as it will be misconstrued as cocky, never being assertive because it will be misconstrued as aggressive, never speaking up for yourself because you will wrongly be called a bitch, never taking charge as you will be hated, never being logical by detaching your emotions as you will be accused of being cold and heartless, never deciding your actions and behavior through reasoning and logical deduction as you will be endlessly pilloried for not thinking with your heart instead of your head, endless pressure at all times to perform emotion and to "wear your heart on your sleeve", constant demands at a societal macro level to perform feminity, maternal care and emotional labor at work meetings & functions, holiday parties/dinners/events, performing emotional labor in all situations and environments regardless of personality (having to attend baby showers at work even if you are an antinatalist and/or childfree woman, having to excessively emote if there is a personal tragedy reported at work with no corresponding requirement for male employees -- miscarriage, hospitalization, accident, death, firing, layoff, etc.).

Rapes, sexual trafficking, sexual slavery, slavery, child sex trafficking, child molestation, child abuse, pedophilia, murders, tortures.

Pharmaceutical industrial complex, pathologizing of normal behavior by the psychiatric industrial complex, overmedicalization, misdiagnoses, overprescribing prescription medication, excessive nonsensical harmful medical interventions, extending life beyond all sense and reason to the point where the interventions are needlessly painful, harmful and completely unnecessary versus accepting death as not just a part of life but a beautiful transformation that should be embraced and not feared, contrived forced and constantly pushed and reinforced fear of death, sexual repression.

Women getting a scarlet letter for being a slut, whore, hoe; men getting an "attaboy" for being a player, stud, ladies man for the exact same sexually promiscuous behavior.

Tyranny of motherhood and demands for women to do constant endless unpaid domestic and emotional labor for their children for absolutely zero compensation and very little social reward beyond perfunctory lip service once a year on Mothers Day.

Endless materialism, endless consumption, endless consumerism, capitalist excess, corporatism, lobbying, fake news, us vs them, tribalism, political prisoners.

Child soldiers, child brides.

Famine, poverty, houselessness, lack of clean water, gun crime, gun deaths, drivebys, AK-47s, machine guns, serial killers, serial rapists, Columbines, Sandy Hooks.

False flag events, paid actors, green screens, sound stages, scripted events, rigged elections, Mandela effects, strangers in Moscow.

Gang violence, frat hazings, initiations, kidnappings, abductions.

Religious cults, priests raping altar boys, Eagle Scouts raping Cub Scouts, ISIS, Al Qaeda, Hamas, IDF, US military.

Elementary schools, churches and theaters being shot up.

Police brutality, Ahmed Arbery, George Floyd, Breonna Taylor, Say Her Name, Hands Up Dont Shoot, Sandra Bland, Trayvon Martin, Its just a bag of Skittles officer.

13 year old boy shot dead, not by the police, but by a Stand Your Ground civilian.

Dont Tread On Me Zionist Proud Boy.

Islamophobia, racism, white supremacy, racially motivated killings, hate crimes.

Donald J. Trump and Elon Musk.

Jeff Bezos and Tim Cook.

Mark Zuckerberg and Peter Thiel.

Roger Goodell and Vince McMahon.

She was asking for it, what was she wearing, was she drinking, why was she out so late, she went upstairs with him what did she expect.

Theres no such thing as marital rape, feminazis invented that term in the 90s.

I dont care if you have a headache.

I dont care if you dont like anal, flip over and stop complaining.

Its not my fault that youre bleeding.

Then stop tensing up and it wont hurt so much.

I bought you the anal numbing cream and youre still complaining? Its lidocaine. Shut up.

I want anal every week so were having it.

I hit you open handed no bruising. Stop complaining.

I want to cum on your face. Theres nothing wrong with facials. Stop complaining. Leave your glasses on. Now take them off. Open your eyes. Keep them open.

Im into golden showers. Stop complaining.

Im into scat. Stop complaining.

Im into spanking. I didnt hit you that hard. Stop complaining.

Im into choking during sex. Its okay to not be able to breathe. Its only for a few seconds. Stop complaining.

I like biting your nipples. Its supposed to hurt. Stop complaining.

I like slapping your cunt. Stop complaining.

I like spitting in your mouth. Stop complaining.

I like roleplaying. Youre going to be 8 years old. Im going to be your uncle. Yes, during sex. Its just a roleplay. Stop complaining.

When can I put one of our videos on stileproject? You'd be good in porn. Why cant I upload them? Why do you say no to everything?

Okay, put your forearms on the floor and your legs on the coach on either side of my waist. No, were going to have anal this way. Im tired of doggy and Im tired of you riding me and Im tired of missionary. Were going to have anal in different positions. Youre tiny and flexible. Do it. Stop complaining.

Then stop gagging and stop throwing up. Theres no reason why you shouldnt be able to deepthroat me. Then work on your gag reflex. Stop complaining.

Get in the bathroom stall. Now. We'll be done in time for the start of Revenge of the Sith. Face away from me. The wall. Stop complaining. Pull your shorts down. Hurry up. No, in the butt. I dont want to wait to get to my house. Hurry up so you can still get your popcorn shrimp. Stay still. Stop moving so I can get it in. Be quiet. Youre not bleeding that much. Stop complaining.

Take your jeans off now. Do it. Im not in the mood for your little girl shit. Take them off. Stop crying. Both pant legs. Now. Hurry up so I can take you home to your fucking father. Stop crying! Be quiet. Hurry up. Its the least you can do after you danced all night at your cousins party.

Dont lie to me. Youve had sex since the restraining order. Shut up. Dont tell me what to do. Nothing hurts. I dont believe you. Hm. It is tight. Youre not hurt. Shut up. Be quiet, let me do this. Stop moving around and stay on top of me. Stay still. Stop shaking. Youre not bruised and youre not swollen. Stop talking. I still dont believe you havent had sex since we stopped dating. Dont talk to me. Leave me alone.

Dark side of private life.

Abusive spouses, murderous spouses.

Respected couple, matriarch and patriach, pillars of the church and community, married for almost 50 years.

Golden anniversary, golden showers.

Dark secrets, dark pasts, hidden criminal pasts, hidden felonies, hidden convictions, hidden prison sentences, lies to daughters, lies to mothers, lies to wives, repressed background check reports.

Might makes right, force, violence, imposing physical will, domination, vanquishing, crushing, destroying.

Humanity has had hundreds of thousands of years to fix these issues.

But we havent.

Were still -- as a species -- murdering, killing, raping, shooting, stabbing, enslaving, ethnic cleansing, erasing, occupying, colonizing, settling, imprisoning, making thousands of animal species extinct, filling thousands of landfills, destroying thousands of acres of rainforests, destroying ecosystems, overfishing, overextracting earths resources, killing indigenous people for diamonds, emeralds, ore, minerals, etc., pillaging, causing climate change, unsustainably raising the planets temperatures, causing wars and genocides, profiting off of and creating jobs for the manufacture and sale of weapons and bombs used to kill civilians mothers daughters grandmothers babies toddlers children teens students hospital patients fathers sons grandfathers teachers doctors nurses volunteers protestors intellectuals conscientious objectors love warriors revolutionaries prophets, AI cloning metaverse social media messaging apps streaming shows endless scroll always on never off, non stop notifications Slack Teams Google Meet Citrix Trello Asana Outlook Gmail corporate slave golden handcuffs modern day plantation.

The solution to all of the above unimaginable suffering is human extinction.

The solution is stop reproducing.

Stop procreating.

Stop pronatalism.

Stop humanity.

Reject societys non-stop endless brainwashing, programming, conditioning, grooming, messaging, demands, pressures and coercion to be pronatalist and reproduce endless bodies for the capitalist Borg machine.

Stop producing workers for them!

Rockefeller invented modern day public education and school systems because he wanted a "docile and obedient" workforce.

Thats all K-12 is because its all it was designed to be -- a feeder system for corporate, nothing more nothing less.

K-12 -- and college -- works exactly the way its designed to.

It breeds endless acquiescence to authoritatian figures.

Coaches, band leaders, music conductors, dance instructors, choir leaders, school counselors, school nurses, teachers, disciplinarians, principal as God figurehead.

Organized religion is the exact same -- endless acquiescence to authoritarian figures (priests, bishops, nuns, ministers, pastors, imams, Catholic pope as ultimate authority and God figurehead).

Corporate is the exact same (supervisor, +1, VP, Officer, CEO as ultimate authority and God figurehead).

Nuclear patriarchal family is the exact same (older siblings, older cousins, aunts/uncles, grandparents, mother, father as ulimate authority and God figurehead).

Government is the exact same (local representatives, mayor, governor, Congressmen/women, Senator, Speaker of the House, Supreme Court justices, President & Commander In Chief as ultimate authority and God figurehead; provinical representatives, Prime Minister, princes & princesses, dukes & duchesses, King as ultimate authorities and God figureheads; Queen is ultimate maternal archetype - "God save the Queen!").

Law enforcement is the exact same (beat and traffic cops, detectives, officers, seargants, captains, Chief of Police as precincts ultimate authority and God figurehead).

Military is the exact same (foot soldiers cannon fodder sausage for the sausage factory, squad leaders, corporals, seargents, captains, generals (1 through 5 star), Chairman of the Joint Chiefs of Staff as ultimate authority and God figurehead).

End the karmic cycle of humanitys universal suffering.

Say no to pronatalism and no to breeding.

Say no to continuing environmental destruction, ecological destruction, ecocide, rainforest destruction, landfills, environmental waste, climate change, ozone depletion, animal species going extinct, wars, genocides, ethnic cleansing, chemical warfare, civilian slaughter, carper bombings, hostage taking, executions, tortures, lynchings, slavery, sexual slavery, sex trafficking, child trafficking, rapes, molestation, abuse, child abuse, domestic violence, murders, shootings, stabbings, drivebys, fatal hazings, kidnappings, abudctions, child soldiers, child brides, political prisoners, civil wars, tribalism, homophobia, transphobia, racism, misogyny, hate crimes, racialized violence, toxic masculinity, military industrial complex, police states, militarism, empire building, war machines, commodification, profiteering, capitalism, excess, materialism, overconsumption, consumerism, lobbying, duopoly, fake news, agendas, misinformation campaigns, forced births, misdiagnoses, overmedicalizations, pathologizing of normal behavior, CTE, concussions, head impacts, permanent brain damage, violence, misogynoir, terorrism, mass shootings, human experimentation, forced sterilizations, mass incarceration, prison industrial complex, military industrial complex, medical industrial complex, corporate plantation, man as machine, dehumanizations, beatings, objectifications, fetishizations, cheapening of human life, commodifications, globalism, slave labor, slave wages, exploitation, endless wars, death squads, rape rooms, comfort women, profiteering, religious cults, forced baptisms, family secrets, abusive family patriachs and matriarchs, capitalist death cult, dictatorships, cults of personality, strongmen, deceivers, manipulators, gaslighters, thieves in the night...

Stop contributing to the endless cycle of human suffering and do something to end it.

Dont reproduce. Dont procreate. Dont have children.

Abstain from sex and be celibate, masturbate, watch porn, read erotica. Or have sex and use birth control, pills, sponges, patches, injections, surgical implants, spermicide, condoms, tubes tied or lasered, withdrawal, Plan B and/or abortion. Or have sex other than vaginal sex (oral, anal, manual, intercrural, etc.).

Just dont add to the already failed and flailing on its ass 7 billion plus strong current human experiment.

[charlie-rulerofhell]

Two days back, Chris did a twitch stream in which he answered fans' questions both in English and in German. So this is yet another translation / summary of all the nice things Chris has to say. It's gonna be way shorter than the Saltatio Mortis podcast, both because I took the notes simultaneously to doing uni work, so I probably didn't catch everything that might be interesting, and because for some answers I couldn't remember in retrospective if he gave them in German or in English, and I didn't want to spam you with info that you might have already heard yourself :D

So, here we go:

when comparing their own smaller concerts with big Iron Maiden performances: "To play in a small club in England in front of 500 people that all know you, that's like going to a small family gathering with family members that you see every day anyway. To play with Iron Maiden in front of 20,000 people is like visiting a huge wedding celebration, where you might know 20 people but the other 200 you have never seen before even though you're related to them, so you first gotta introduce yourself." (just loved the analogy here :D)

about the next record: At the end of the year, a full cover album is gonna be released that will style-wise stay similar to the B&G era, and apparently the 15 years anniversary tour next year will also keep that style. After that, however, Chris said that the only logical consequence for them, after all this brightness and colour, was to go into the complete opposite direction. So the next (proper) record will be the darkest album that they have done so far (with 'dark' not necessarily meaning 'hard', so it's not gonna be Death Metal, but it will in fact keep parts of the current 80s vibe). There is some concept that is already planned out, but it's not a religious one, nor a mythological one. The theme will be rather dark-romantic, dealing with our human emotional abysses.

Someone commented: "On pictures you seem quite photogenic", to which Chris jokingly replied that this were his big secret: He's not really photogenic, but he's good at seeming that way. The question continued with asking if he had ever modelled or been asked to model, and he gave some interesting reply. In fact, Chris has been asked for various model jobs in the past, but he always refused. He said that he would generally be up for the idea, but if he does promote a product / a company with his face, he has to be able to fully stand behind it. Sometimes it might not have been the choice of clothing etc. that he would personally like, but in most cases the decision was due to the company that he could not support, for example if the clothes were produced under unethical conditions. He also mentions that he had had a request for some allergy meds recently, that he actually would have liked to do (as someone who struggles with allergies himself), but the pharma trust responsible for that product worked with animal testing, so again, he refused.

he made a joke about Klaas being so small that he would actually be standing below the camera in that moment, holding up signs with jokes for Chris to read :D

about the decision for B&G for the ESC instead of One Last Song and The Curtain Falls that were also on the shortlist: With both songs the main problem was that they wouldn't have managed to produce a qualitative music video in time. OLS was also too long, and Chris didn't feel good with any parts being cut, while TCF was still kind of in the production phase. B&G had the full package: it is catchy and recognisable, has a good message, a provocative song title that also reflects the bands different sides, there was a music video and even a whole album of the same name.

someone prompts the idea of a calendar with all of the beautiful pics that Lennard is taking, and Chris likes the idea and actually writes it down! (thinking about 2 group pictures + 1 for the cover and 2 x 5 portrait shots)

he likes the pink hair colour atm (even if it was actually supposed to be red), and thinks about bleeching it platinum again later this month, while still keeping half the hair pink (I think we would all love to see that ;D)

about never playing Not My Enemy: Chris says he is kinda scared to play it live. He wrote the song shortly after the start of the war against the Ukraine, so the meaning is very important to it. He would not want to play it at a festival or at any other place where most people don't know the song and the lyrics, and might even start moshing to it. If it were at a full LOTL show where most people know the song and can feel the meaning, then maybe, but generally it gives him physical pain to even think about performing it live.

and finally about collaborations with other ESC artists: What Chris can confirm is that there will be songs written together with La Zarra (as soon as they find the time). Besides that, there is also another collab that is already underway, but Chris does not yet want to give away with whom

Alright, that's all of my notes. If I missed anything that you are interested in, or you want a full translation of any part, as always, feel free to hit me up :)