#Uterine Cancer Drugs

[mrunalnerkarblog]

Uterine Cancer Drugs Market is Expected to Gain Popularity Across the Globe by 2028

Uterine cancer is one of the most common gynecologic malignancy among female cancer patients. This uterine cancer is of two types: endometrial cancer and uterine sarcoma. Endometrial cancer is caused due to uncontrolled growth of inner linings of uterus. Endometrial cancer is often curable, however, uterine sarcoma is rare cancer, which develops in the muscle and supporting tissues of the uterus (womb). According to National Cancer Institute, Megestrol Acetate is only drug approved by U.S. Food and Drug Administration (FDA) for the treatment of endometrial cancer till March 2016. Diagnosis of both types of uterine cancer is done through endometrial biopsy, colposcopy or Pap smear screening test.

Uterine Cancer Drugs Market Drivers

Increasing funding for cancer research, rising insurance coverage, and increasing number of new targeted cancer drugs are supporting the revenue growth of uterine cancer drugs market size. For instance, National Cancer Institute, in 2015, invested around US$ 4,480 million on cancer research, which include uterine cancer, cervical cancer, lung cancer, colorectal cancer, liver cancer, breast cancer, leukemia, and ovarian cancer. Furthermore, according to the American Cancer Society, U.S. has spent around US$ 87.8 billion in 2014, on cancer research, in which the major cost accounting for around 44%, was paid by private insurance companies.

Uterine Cancer Drugs Market - Regional Analysis

Geographically, uterine cancer drugs market is segmented into North America, Latin America, Europe, Middle East, Asia Pacific, and Africa. According to World Health Organization (WHO) 2018 data findings, cervical cancer is the fourth most frequent type of cancer in women, which accounted for an estimated 530,000 new cases in 2012, representing 7.9% of all female cancers. Furthermore, according to WHO: 2018, around 90% the 270,000 deaths from cervical cancer in 2015 are occurred in low- and middle-income countries. Furthermore, the prevalence of endometrial cancer is higher in developed economics such as the in North America and the Europe, owing to changing lifestyles of women in these countries. The prevalence of uterine cancer is more common in women aged 50 years and above.

[drajaysharma]

Dr. Ajay Sharma is a best chemotherapy doctor in delhi, providing chemotherapy treatment for cancer in delhi; find more about chemotherapy treatment for breast cancer in delhi, cervical cancer, stomach cancer, lung cancer, colon cancer etc.

[woman-for-women]

"For years, Sharissa Derricott, 30, had no idea why her body seemed to be failing. At 21, a surgeon replaced her deteriorated jaw joint. She’s been diagnosed with degenerative disc disease and fibromyalgia, a chronic pain condition. Her teeth are shedding enamel and cracking.

None of it made sense to her until she discovered a community of women online who describe similar symptoms and have one thing in common: all had taken a drug called Lupron.

Thousands of parents chose to inject their daughters with the drug, which was approved to shut down puberty in young girls but also is commonly used off-label to help short kids grow taller.

The drug’s pediatric version comes with few warnings about long-term side effects. It is also used in adults to fight prostate cancer or relieve uterine pain and the Food and Drug Administration has warnings on the drug’s adult labels about a variety of side effects.

More than 10,000 adverse event reports filed with the FDA reflect the experiences of women who’ve taken Lupron. The reports describe everything from brittle bones to faulty joints.

In interviews and in online forums, women who took the drug as young girls or initiated a daughter’s treatment described harsh side effects that have been well-documented in adults.

Women who used Lupron a decade or more ago to delay puberty or grow taller described the short-term side effects listed on the pediatric label: pain at the injection site, mood swings and headaches. Yet they also described conditions that usually affect people much later in life. A 20-year-old from South Carolina was diagnosed with osteopenia, a thinning of the bones, while a 25 year-old from Pennsylvania has osteoporosis and a cracked spine. A 26 year-old in Massachusetts needed a total hip replacement. A 25-year-old in Wisconsin, like Derricott, has chronic pain and degenerative disc disease.

“It just feels like I’m being punished for basically being experimented on when I was a child,” said Derricott, of Lawton, Okla. “I’d hate for a child to be put on Lupron, get to my age and go through the things I have been through.”

PBS - Women fear drug they used to halt puberty led to health problems (2017)

[homara8524]

Status Report and Mail Order Notification

Good evening brothers and sisters abroad. After the rush of events, I am finally getting settled. Today, I'd like to give you an update on my recent activities and announce the mail order of my original drawings and new publications.

The rush of events started on September 15. It all started with my best friend from high school and I going to LUPICIA, a famous Japanese tea company, to get some tea cakes for the upcoming events.

On 9/23, I exhibited at a joint Touhou event in Kyoto to display and distribute my new book and original artwork, and on 9/30, I was asked to be a second for my master's powerlifting competition, so I was engaged in seconding.

After that, I participated in Kouroumu, a Touhou event held in Osaka, where I exhibited and distributed my original artwork. I have now been working at the event for 4 weeks in a row.

And now that things have finally settled down, we have registered our new publications and original artwork on our mail order site! We have also registered them with the proxy purchase service in Booth's system so that they can be purchased by people overseas. We will charge a small fee for this service, but it will be available to anyone overseas. Of course they will be framed 💕.

In fact, we also have new postcard-sized original drawings of Eastern characters that we have not yet posted here on our website.

And here is a request for the future. My circle currently consists mainly of Touhou character illustrations, but I have started to work on original illustrations as well. And now I am raising funds for my hospitalization and surgery to remove my uterine cancer.

The date for the surgery itself has already been set, and after I finish a national powerlifting competition next month, I will be hospitalized for a little less than two weeks from November 20 to observe the surgery and post-operative condition.

Currently, due to a worsening of a chronic illness that occurred the year before last, I am unable to engage in normal work, and I am still unable to engage in any work other than drawing illustrations. I am a freelance illustrator and earn almost no income. I do not have enough money to face the hospitalization and surgery next month.

So I would like to ask my overseas followers to help me. Please spread the word about my original illustrations to people who are not just Touhou lovers. And if you think it is a wonderful work of art, whether you like the character or not, please welcome the original.

If as many people as possible welcome my original drawings and new publications, it will help to pay for my uterine cancer surgery and subsequent hospital visits.

Most importantly, it will also help fund the purchase of expensive immunosuppressive drugs for my uterine cancer and other incurable diseases.

Please, can you all help me?

[detransition]

"For years, Sharissa Derricott, 30, had no idea why her body seemed to be failing. At 21, a surgeon replaced her deteriorated jaw joint. She’s been diagnosed with degenerative disc disease and fibromyalgia, a chronic pain condition. Her teeth are shedding enamel and cracking.

None of it made sense to her until she discovered a community of women online who describe similar symptoms and have one thing in common: all had taken a drug called Lupron.

Thousands of parents chose to inject their daughters with the drug, which was approved to shut down puberty in young girls but also is commonly used off-label to help short kids grow taller.

The drug’s pediatric version comes with few warnings about long-term side effects. It is also used in adults to fight prostate cancer or relieve uterine pain and the Food and Drug Administration has warnings on the drug’s adult labels about a variety of side effects.

More than 10,000 adverse event reports filed with the FDA reflect the experiences of women who’ve taken Lupron. The reports describe everything from brittle bones to faulty joints.

In interviews and in online forums, women who took the drug as young girls or initiated a daughter’s treatment described harsh side effects that have been well-documented in adults.

Women who used Lupron a decade or more ago to delay puberty or grow taller described the short-term side effects listed on the pediatric label: pain at the injection site, mood swings and headaches. Yet they also described conditions that usually affect people much later in life. A 20-year-old from South Carolina was diagnosed with osteopenia, a thinning of the bones, while a 25 year-old from Pennsylvania has osteoporosis and a cracked spine. A 26 year-old in Massachusetts needed a total hip replacement. A 25-year-old in Wisconsin, like Derricott, has chronic pain and degenerative disc disease.

“It just feels like I’m being punished for basically being experimented on when I was a child,” said Derricott, of Lawton, Okla. “I’d hate for a child to be put on Lupron, get to my age and go through the things I have been through.”

Women fear drug they used to halt puberty led to health problems (PBS) graphic from woman-for-women | thinking of detransition? you are not alone

[justinspoliticalcorner]

Robyn Pennacchia at Wonkette:

Last week, Louisiana lawmakers empowered child rapists by voting down a bill that would have allowed an exception in their abortion ban for their victims. This week, they’re looking into classifying abortion pills as a Schedule IV “controlled substance” so that they can harshly prosecute people for helping to distribute them to those in need. The provision was added as an amendment to SB276, a bill that “creates the crime of coerced criminal abortion by means of fraud to prohibit a third-party from knowingly using an abortion-inducing drug to cause, or attempt to cause, an abortion on an unsuspecting pregnant mother without her knowledge or consent and amends various abortion criminal laws to add the crime of attempted abortion.”

It is deeply concerning that Louisiana legislators are wholly unaware that all of this is already illegal. It is illegal, except in some emergency situations and even then only by medical professionals, to give anyone any kind of medication without their knowledge and informed consent. If they think this is legal, well, I wouldn’t leave my drink around a single one of them, is all I’m saying. It’s also clear that they don’t really understand what controlled substances are, why some drugs are scheduled and others are not, nor anything about the specific drugs they are trying to control. Misoprostol, for instance, is primarily used to prevent ulcers from NSAIDs, as well as to help stop postpartum hemorrhaging after a miscarriage. Mifepristone is sometimes used during labor, during IUD placement, during cancer biopsies, for Cushing’s syndrome and uterine fibroids.

[...] The bill’s sponsor, Republican state Sen. Thomas Pressly, introduced it partially for personal reasons, because his sister’s ex-husband actually did secretly dose her with an abortion drug, and was not, in Pressly and his sister’s estimation, punished severely enough for it. He served 180 days in jail, and the bill would raise that to 10 years and up to $75,000 in fines. It would be one thing to increase the penalties for dosing anyone in any kind of way, but there’s a reason they’re specifying abortion drugs. What they want is to prevent people from getting them for women who want to take them voluntarily but cannot because of their state’s gross law, and to institute major penalties for this. What they want is to be able to better track doctors who may still be prescribing these pills to abortion-seeking patients for reasons other than abortion.

Louisiana's SB276 bill to classify abortion pills such as mifepristone and misoprostol as "controlled substances" are an attack on reproductive freedom and family planning.

[virtualelectronicshub]

Radiation Therapy Explained: Benefits, Process, and Potential Side Effects

Radiation therapy is a type of cancer treatment that uses high doses of radiation to kill cancer cells and shrink tumours. Radiation therapy works by damaging the DNA of cancer cells, which prevents them from dividing or growing. Radiation therapy can be delivered externally or internally, depending on the type and location of the cancer.

Radiotherapy is a rapidly growing technically advancing speciality.

The most advanced radiotherapy techniques include:

ETHOS, Linear Accelerators with Artificial Intelligence.

MR Linear Accelerators, where a MR imaging machine is used as part of treatment for better imaging and treatment position and precision.

Cyberknife:  A miniature linear accelerator mounted on a robotic arm, used for high precision radiotherapies to like brain tumors and recurrent tumors close to critical organs.  Cyberknife is used even in noncancerous brain tumors like schwannommas and trigeminal nerve roots alleviating the pain and suffering of trigeminal neuralgia.

Proton Beam Therapy.

3D conformal radiation therapy.

Intensity-modulated radiation therapy (IMRT)

Volumetric modulated radiation therapy (VMAT)

Image-guided radiation therapy (IGRT)

Stereotactic radiosurgery (SRS)

Brachytherapy.

Superficial x-ray radiation therapy (SXRT)

Intraoperative radiation therapy (IORT)

Benefits of Radiation Therapy

For many common cancers, such as breast cancer, bowel cancer, uterine cancer, skin cancers and prostate cancer, radiation therapy is highly effective in reducing the risk of cancer recurrence if delivered either before or after surgery. In some cancers (for example (prostate, head and neck, bladder, lung, cervix and skin cancers), radiation therapy, with or without drug therapy, can be used as the main curative treatment and in this way avoids the risks of surgery and the removal of organs.

For some cancers that are too advanced to be cured, radiation therapy is very effective for pain and other problems caused by cancer, such as bleeding from the lung or bladder. For example, pain in the bones from the spread of cancer can be improved significantly or be completely removed in around 75% of patients.

New technological advances in radiation therapy have made life better for cancer patients in recent years by making treatments even quicker, more accurate and effective.

Radiation therapy can help:

●      Cure cancer by destroying all the cancer cells in a tumour.

●      Control cancer by slowing down its growth or preventing it from spreading to other parts of the body.

●      Relieve symptoms such as pain, bleeding, or pressure caused by a tumour.

Process of Radiation Therapy

The process of radiation therapy varies depending on the type and stage of the cancer, the goals of the treatment, and the patient’s overall health and preferences. Generally, the process involves:

Radiation therapy is a type of cancer treatment that uses high energy beams to destroy cancer cells and shrink tumours.

The American Cancer Society notes that more than half of people with cancer receive radiation therapy.

Radiation damages genetic material called DNA inside of cancer cells. If the cancer cell cannot repair the DNA, the cell will not be able to produce new cells and may die.

The radiation may injure noncancerous cells, but most are able to recover.

A person’s treatment team will carefully plan radiation therapy to minimise damage to normal tissues and organs.

●  A consultation with a radiation oncologist, who is a doctor who specialises in treating cancer with radiation.

● A planning session is where a radiation therapist will keep the patient  immobilised in position with thermoplastic masks, then imaging tests such as CT scans or MRI scans are used to map out the exact location and size of the tumour and the surrounding normal tissues.

●  A simulation session, where a radiation therapist will position the patient on a table and mark the skin with ink or tattoos to guide the delivery of the radiation beams.

● A treatment session, where the patient will lie still on a table while a machine called a linear accelerator will deliver the radiation beams to the tumour from different angles. The treatment session may last from a few minutes to an hour, depending on the dose and type of radiation therapy. The patient may need to have several treatment sessions over days, weeks, or months.

Potential Side Effects of Radiation Therapy

Radiation therapy can cause side effects that vary depending on the part of the body being treated, the dose and type of radiation therapy, and the patient’s individual response. Some common side effects include:

●      Skin changes such as redness, dryness, itching, peeling, or blistering.

●      Fatigue or tiredness that may interfere with daily activities.

●      Nausea, vomiting, diarrhoea, or constipation that may affect appetite and    digestion.

●      Hair loss in the area being treated.

●      Mouth sores or dry mouth that may make eating or swallowing difficult.

●      Headaches or memory problems that may affect concentration or mood.

●      Inflammation or infection of the bladder or rectum that may cause pain or bleeding during urination or bowel movements.

Most side effects are temporary and will go away after the treatment is completed. However, some side effects may be long-lasting or permanent, such as infertility, nerve damage, lymphedema (swelling caused by fluid build-up), or secondary cancers.

Radiation therapy is an effective and safe way to treat many types of cancer. However, it is not suitable for everyone and it may have some risks and limitations. Therefore, it is important to discuss with your doctor about the benefits and drawbacks of radiation therapy for your specific situation before starting the treatment.

For more details click on the link 👇🏻 https://bit.ly/3osreVo

[sirfrogsworth]

Any recommendations for a comprehensive video on puberty blockers?

I feel like I could be more informed but I just can't read anymore. My reading concentration is just gone after getting very little sleep.

It's crazy how hard conservatives are going after a medication that is only prescribed to a few thousand kids. And they seem to be really hung up on the fact that these drugs were used for chemical castration of criminals in the past. A sordid history does not mean the medication shouldn't be used anymore. Shock treatments were used to discipline mental patients in the 60s. Now they are a safe and viable therapy for treatment resistant depression.

And drugs are often used for multiple purposes. Viagra can treat heart issues. Puberty blockers can treat prostate cancer and uterine bleeding. I think they just like the fact they can say scary words like "castration" and "pedophile" and relate it to trans healthcare--even if it is only tangential.

If you need to resort to trickery like that, you probably don't have a strong argument.

I found this exchange especially frustrating.

WHICH IS IT, MASON?

[unwelcome-ozian]

What information do you have about Johnson & Johnson?

Alza filed an NDA for the transdermal opioid analgesic product in December 1987 for post-operative use and for the relief of chronic cancer pain. Developed by J&J subsidiary Janssen Pharmaceutica, fentanyl has been marketed since 1968 under the Sublimaze brand. The drug is currently approved for I.V. administration and used primarily as a short-acting analgesic during anaesthesia. "This new drug delivery system will make it possible for the first time to use fentanyl . . . outside the operating room to control moderate to severe pain." Source

US opioids: Johnson and Johnson and drug distributors offer $26bn to end thousands of lawsuits. Source

The drug company Johnson & Johnson (J&J) has expressed regret after court documents unsealed in talcum powder litigation showed that it funded a 1971 study in which Pennsylvania prison inmates, most of them black, were injected subcutaneously with asbestos. Source

Asbestos Prisoner Study May Spell More Problems for Johnson & Johnson

WASHINGTON - Global health care giant Johnson & Johnson (J&J) and its subsidiaries will pay more than $2.2 billion to resolve criminal and civil liability arising from allegations relating to the prescription drugs Risperdal, Invega and Natrecor, including promotion for uses not approved as safe and effective by the Food and Drug Administration (FDA) and payment of kickbacks to physicians and to the nation’s largest long-term care pharmacy provider.  The global resolution is one of the largest health care fraud settlements in U.S. history, including criminal fines and forfeiture totaling $485 million and civil settlements with the federal government and states totaling $1.72 billion. Source

Johnson & Johnson paused all clinical trials of its experimental COVID-19 vaccine after a study participant became sick with an "unexplained illness."

Johnson & Johnson has suspended international trials of a drug in the same class as an experimental drug made by Portuguese pharmaceutical company Bial, whose tests in France left one person brain dead and five others hospitalised. Source

1982 - McNeil

Product Recalled - Tylenol (acetaminophen) capsules

Reason for Recall - Medicine laced with potassium cyanide (poison) resulting in several patient deaths.

2009 to 2011 - McNeil

Product Recalled - Several OTC medicines including Tylenol, Motrin, Benadryl, St. Joseph aspirin, Sudafed, Pepcid, Mylanta, Rolaids, Zyrtec, Zyrtec Eye Drops (tens of millions of bottles)

Reason for Recall - Unpleasant smells causing nausea; tiny metal shards in liquid medicines; wrong ingredient levels

2010 - DePuy [Pinnacle Systems]

Product Recalled - ASR Hip Resurfacing System and ASR XL Acetabular System (metal-on-metal hip implants)

Reason for Recall - Metal poisoning (metallosis); loosening of the implant or joint dislocation; additional surgeries

2012 - Ethicon

Product Recalled - Gynecare Prolift Kit, Gynecare Prolift+M Kit, Gynecare TVT Secure and Gynecare Prosima Pelvic Floor Repair System Kit (transvaginal mesh implants)

Reason for Recall - Perforation of organs; vaginal bleeding and scarring; mesh erosion; severe pain

2014 - Ethicon

Product Recalled - Power Morcellators

Reason for Recall - Spread of uterine cancer; rapid progression of the disease; death

2019 – Johnson & Johnson

Product Recalled – 33,000 bottles of Johnson’s Baby Powder

Reason for Recall – The FDA found a small amount of asbestos — a known carcinogen — in a sample

Xarelto

Number of Lawsuits - 13,511

Injuries - severe, sometimes deadly bleeding events, blood clots, wound leaks, infection

J&J was involved in seven of 2017’s top ten health-care-related verdicts.

The company was also involved in the third-largest pharmaceutical settlement with the U.S. Department of Justice. In 2013, J&J paid the Justice Department more than $2.2 billion. The settlement resolved civil and criminal allegations involving Risperdal, Invega and Natrecor.

May 2017

J&J paid $33 million to most U.S. states and the District of Columbia. The states charged J&J with misrepresenting the manufacturing practices behind certain drugs. This included its Motrin products. These products were later recalled.

Oz

[drshivanisachdevgoursciivf]

Demystifying Female Infertility: Exploring 5 Potential Causes

Female infertility is a complex condition that affects a significant number of women around the world. The inability to conceive can be emotionally challenging and often prompts a search for answers. While infertility can have various underlying causes, this article aims to shed light on five potential factors that may contribute to female infertility. By understanding these causes, individuals and healthcare professionals can work together to explore appropriate interventions and treatment options.

Hormonal Imbalances: One of the common causes of female infertility is hormonal imbalances. Hormones such as estrogen, progesterone, luteinizing hormone (LH), and follicle-stimulating hormone (FSH) play vital roles in regulating the menstrual cycle and promoting ovulation. Any disruption in the delicate balance of these hormones can lead to irregular or absent ovulation, making it difficult for women to conceive.

Structural Abnormalities: Structural abnormalities within the reproductive system can also contribute to female infertility. Conditions such as polycystic ovary syndrome (PCOS), endometriosis, uterine fibroids, or blocked fallopian tubes can hinder the fertilization process or implantation of a fertilized egg. These conditions may require medical intervention or surgical procedures to restore fertility.

Age-related Factors: Advancing age is a significant factor that impacts female fertility. As women age, the quantity and quality of their eggs decline. The chances of chromosomal abnormalities and miscarriages increase, making it more challenging to conceive naturally. It is important for women to be aware of their reproductive timeline and seek assistance from healthcare professionals if they face difficulties in conceiving as they get older.

Lifestyle Factors: Certain lifestyle factors can contribute to female infertility. Obesity, excessive alcohol consumption, smoking, drug abuse, and high levels of stress can all have adverse effects on reproductive health. These factors can disrupt hormonal balance, interfere with ovulation, and affect the overall fertility of women. Adopting a healthy lifestyle that includes regular exercise, a balanced diet, and stress management techniques can positively impact fertility.

Medical Conditions and Treatments: Certain medical conditions and treatments can also cause infertility in females. Conditions such as thyroid disorders, autoimmune diseases, diabetes, and cancer can affect fertility. Additionally, treatments such as chemotherapy and radiation therapy can damage the reproductive organs and impair fertility. It is crucial for women with these conditions to consult with their healthcare providers to explore fertility preservation options before undergoing such treatments.

Conclusion: Understanding the potential causes of female infertility is crucial for women and healthcare professionals alike. By identifying these factors, individuals can take proactive steps to address and manage their reproductive health. It is important to remember that each case of infertility is unique, and a comprehensive evaluation by a healthcare professional is essential to determine the underlying cause and develop an appropriate treatment plan. With advancements in medical science and fertility treatments, many individuals can still achieve their dream of starting a family despite facing infertility challenges.

Looking for a Free IVF Consultation with an IVF Specialist? Contact Dr. Shivani Sachdev Gour.

[drajaysharma]

Dr. Ajay Sharma is a best chemotherapy doctor in delhi, providing chemotherapy treatment for cancer in delhi; find more about chemotherapy treatment for breast cancer in delhi, cervical cancer, stomach cancer, lung cancer, colon cancer etc.

[stormofneurosis]

*ahem*

"Medical standard", at least where drug trials are concerned, treats women as "men with pesky hormones". Most if not all drugs specifically for women have been tested primarily (90-95% of the subjects) on men. Including ones specifically meant to treat/prevent uterine cancer.

In conclusion:

FUCK "MEDICAL STANDARD" WHEN IT COMES TO WHAT YOUR BODY NEEDS

we should hype up bottom surgery more i think. both twitter transphobes and chronically online trans people really like to be disgusted at phalloplasty, vaginoplasty, ext. and i really think we should treat them as cool and sexy and neutral like top surgery scars or whatever

[dhenrynyc]

Effective Treatments of Fibroids in Uterus Near NYC: Regain Your Health

Uterine fibroids can be a significant health concern, affecting many women with symptoms ranging from heavy menstrual bleeding and pain to bloating and discomfort. While these non-cancerous growths are common, finding the right treatment to manage symptoms is essential to restoring well-being. For women searching for "treatments of fibroids in uterus near NYC," understanding the available options can make all the difference. At Bioidentical Hormones NYC, we specialize in providing effective, personalized treatments for fibroids, prioritizing both comfort and effectiveness.

Understanding Fibroids and Symptoms

Fibroids are muscular tumors that grow on the uterus and vary in size, quantity, and location. While some women may experience minimal symptoms, others may struggle with pain, irregular menstrual cycles, and even fertility issues. Hormonal imbalances can often contribute to fibroid growth, which is why tailored treatments focusing on hormone balance can be a game-changer in managing fibroid symptoms effectively. For those seeking effective "treatments of fibroids in uterus near NYC," options like hormone therapy and specialized care can significantly improve quality of life.

Top Treatment Options for Fibroids Near NYC

Hormone Therapy

Hormone therapy can be effective in managing fibroid symptoms. Treatments focus on balancing hormones, particularly estrogen and progesterone, which play a role in fibroid growth. Bioidentical Hormone Replacement Therapy (BHRT) is a popular, targeted treatment offered at Bioidentical Hormones NYC. This natural approach uses hormones that closely mimic those in the body, reducing fibroid size and providing symptom relief without the intense side effects often seen in synthetic hormone therapies.

Non-Invasive Procedures

Uterine Fibroid Embolization (UFE) is a less invasive, highly effective procedure. UFE works by cutting off the blood supply to fibroids, causing them to shrink and die. This minimally invasive option allows women to avoid surgical risks, making it an attractive choice for those with larger or more numerous fibroids.

Medication

Medications like GnRH agonists are often prescribed to reduce the size of fibroids. While these can be effective for symptom relief, they are often short-term solutions due to side effects. Additionally, anti-inflammatory drugs and oral contraceptives can sometimes help manage the symptoms but won’t directly reduce fibroid size.

Surgical Options

For more severe cases, surgical options such as a myomectomy (removal of fibroids) or a hysterectomy (removal of the uterus) may be considered. These procedures are typically recommended for women who haven’t found relief with other treatments. Myomectomy is a particularly effective option for those wanting to preserve fertility while managing fibroids.

Benefits of Bioidentical Hormone Therapy for Fibroids

Bioidentical Hormones NYC offers a specialized approach using Bioidentical Hormone Replacement Therapy (BHRT) for women experiencing fibroid symptoms. BHRT works by balancing estrogen levels, which can effectively reduce the size and symptoms of fibroids. Unlike synthetic hormone therapy, BHRT provides a natural alternative, closely mimicking the body’s hormones and offering relief from symptoms with fewer side effects.

Why Choose Bioidentical Hormones NYC?

At Bioidentical Hormones NYC, our approach focuses on personalized care, ensuring each patient receives a treatment plan tailored to her unique hormonal profile. Focusing on hormone balance addresses the root cause of fibroid growth, providing a solution that works in harmony with your body.

Take Charge of Your Health Today

Finding the right treatment for uterine fibroids is key to reclaiming your health and comfort. With personalized treatment options and a team dedicated to your wellness, Bioidentical Hormones NYC is here to help you find relief.

Ready to take control of your health? Contact us today to learn more about your personalized treatment options!

[zany1122]

Best IVF Specialist In India

IHR Kolkata, a well-respected fertility clinic in Kolkata, offers a wide range of fertility treatments including best ivf centre in india. In vitro fertilization (IVF), one of the world’s premier assisted reproductive technologies, offers couples suffering from infertility an effective solution. In the IVF procedure, the eggs from the ovaries of the woman are taken and fertilized in a lab dish with sperm. The embryos that are created will then be transferred into the uterus of the woman in order to achieve a successful pregnancy. IHR Kolkata offers IVF treatments by highly experienced doctors and embryologists who collaborate to offer customized care and assistance to couples undergoing IVF in Kolkata. With the help of IVF, couples experiencing infertility have an opportunity to conceive and begin building their family.

IVF treatment in Kolkata involves multiple stages such as ovarian stimulator, egg retrieval and fertilization, culture of embryos, and transfer. Our fertility specialists closely monitor every step of the process to create a customized treatment plan to meet the needs of each patient and enhance their chances of success.

When is IVF Treatment Recommended?

IVF treatment should generally be considered by women under 43 who have tried for two years to conceive with unprotected sexual relations without success. These treatments can help treat infertility caused by blocked fallopian tubes, genetic issues or male infertility factors. In some cases, less invasive procedures such as fertility drugs or intrauterine insemination may be tried first. However, IVF treatment in Kolkata may be recommended to women in their mid-30s when other options have failed or when other health conditions such as fallopian tube damage, ovulation disorders, endometriosis, uterine fibroids, previous tubal sterilization or removal, impaired sperm function, unexplained infertility, genetic disorders, or for fertility preservation due to cancer or other health conditions. Therefore it is wise to discuss all available treatments with a fertility specialist prior to embarking upon IVF therapy treatment plan In Kolkata. It is important to discuss all available options with a fertility specialist to determine the best course of IVF treatment In Kolkata.

Why Choose IHR India For IVF treatment in Kolkata?

At IHR Kolkata, we offer the best ivf specialist in india, providing couples struggling with infertility the opportunity to achieve their dream of having a child. We use advanced medical technologies and modern infrastructure to offer personalized treatment plans tailored to the unique needs of each patient. Our team of experienced and caring medical staff works closely with patients at every step, providing support and guidance throughout their fertility journey. With a high success rate of 70%, we are a leading choice for both domestic and international patients that are seeking for ivf specialist in kolkata. We are committed to making superior infertility treatments that are affordable and accessible to a larger population, helping more couples fulfill their dream of parenthood.

Our team of experts, fertility breakthrough results and a 70% success rate made us a unique option for desired couples. We are trying our best to make superior infertility treatments inexpensive to a larger population.

Reasons To Choose Us:

1. We are passionate about helping infertile couples with our definite solutions. 2. All our methods are well-tested and tried. 3. We always focus on reducing the mental and physical stress of our patient so that they go successfully in their IVF treatment. 4. Our medical staff is supportive and help you in every step of your IVF fertility journey. 5. We deliver supreme services for male and female infertility that results in better outcomes for both mothers and babies.

Do you have difficulty conceiving a child? Couples who have failed to conceive using other methods often consider IVF treatment in Kolkata. Here are some reasons why couples consider IVF treatment:

1. Tubal Factor: When the fallopian tubes become blocked or damaged, IVF may be the only viable way to achieve pregnancy. Since the fallopian tubes connect ovaries to womb, and an egg cannot travel down them without impediments, pregnancy cannot occur naturally.

2. Male Infertility: It is a common reason for infertility in couples. If the male partner has low sperm count or abnormalities that hinder fertilization of the egg, IVF with ICSI is frequently recommended for a successful pregnancy and biological baby.

3. Age-related Infertility: As women age, their ovarian function decreases and they may find it increasingly difficult to get pregnant. Some women’s ovarian function decreases earlier, making it necessary to consider IVF treatment sooner.

4. PCOS: Patients living with Polycystic Ovary Syndrome (PCOS) frequently have difficulty becoming pregnant. IVF treatment may be beneficial and help lower some risk factors.

5. Undetermined Infertility: Approximately 20% of couples experience unexplained infertility, without any identifiable reason. IVF treatment has proven to be successful in such cases.

6. Genetic Disease: Couples suffering from genetic disorders who experience repeated miscarriages should consider IVF treatment as the only option for a successful pregnancy.

[ankitblogs0709]

Selective Estrogen Receptor Modulators Market - Key Industry Dynamics, Analysis and Key Industry Dynamics

The Selective Estrogen Receptor Modulators (SERMs) market is experiencing growth due to their increasing use in the treatment of various hormone-related conditions. SERMs are a class of drugs that act on the estrogen receptor, selectively activating or blocking estrogen’s effects in different tissues. They are widely used in the treatment and prevention of breast cancer, osteoporosis, and other estrogen-related disorders. The growing prevalence of breast cancer and osteoporosis, particularly in postmenopausal women, is a major driver for the market. Additionally, advancements in drug development, along with ongoing research into expanding the therapeutic applications of SERMs, are fueling market growth. Increased awareness about women's health, coupled with government initiatives to address cancer and bone health, also contribute to the expanding market. However, challenges such as potential side effects and competition from alternative treatments may limit the market's growth. Despite this, the demand for SERMs is expected to rise as more targeted therapies are developed to improve patient outcomes with fewer side effects.

The Selective Estrogen Receptor Modulators (SERMs) market is witnessing several innovative trends that are shaping its growth and evolution. These trends include:

1. Development of Next-Generation SERMs

Pharmaceutical companies are focusing on the development of next-generation SERMs with improved efficacy and safety profiles. These newer compounds are being designed to provide more targeted effects, minimizing side effects such as hot flashes, blood clots, and the risk of uterine cancer. This innovation is aimed at expanding the therapeutic applications of SERMs to treat a wider range of conditions, including new types of cancers and metabolic disorders.

2. Combination Therapies

An emerging trend in the SERMs market is the development of combination therapies that pair SERMs with other classes of drugs, such as aromatase inhibitors, bisphosphonates, or immune-modulating agents. These combination approaches are being explored to enhance treatment efficacy, particularly in breast cancer and osteoporosis. By combining SERMs with other treatments, the goal is to achieve better patient outcomes and address multiple pathways involved in disease progression.

3. Personalized Medicine and Biomarker Research

The rise of personalized medicine is impacting the SERMs market as researchers work on identifying biomarkers that can predict how individual patients will respond to SERM therapy. This trend is driving the development of more personalized treatment strategies, ensuring that SERMs are prescribed to patients most likely to benefit based on their genetic and hormonal profiles. This approach could lead to more effective, tailored therapies with fewer side effects.

4. Use of SERMs in New Therapeutic Areas

Beyond their established use in breast cancer and osteoporosis, SERMs are being investigated for potential therapeutic applications in other conditions such as endometriosis, polycystic ovary syndrome (PCOS), cardiovascular diseases, and metabolic disorders. Expanding the use of SERMs into these areas represents a significant growth opportunity and could lead to new treatments for hormone-related conditions affecting a broader patient population.

5. Focus on Postmenopausal Health

The aging population, particularly the growing number of postmenopausal women, is driving innovation in SERMs designed specifically to address postmenopausal health issues. SERMs are being increasingly used to treat osteoporosis and reduce the risk of fractures in postmenopausal women. New research is also exploring their potential in managing menopausal symptoms, preventing cardiovascular diseases, and improving overall health and quality of life in older women.

6. Advances in SERM Drug Delivery Systems

Innovative drug delivery systems, such as transdermal patches, oral disintegrating tablets, and long-acting injectable forms, are being developed to enhance patient compliance and convenience. These novel delivery methods can improve the bioavailability of SERMs, reduce dosing frequency, and minimize gastrointestinal side effects, making treatment more accessible and appealing to patients.

7. Research into Tissue-Selective SERMs

Research into tissue-selective SERMs is gaining momentum. These SERMs are designed to selectively activate or inhibit estrogen receptors in specific tissues, such as bone or breast tissue, while avoiding effects in other areas like the uterus. This selectivity reduces the risk of unwanted side effects and enhances the safety profile of the drug. Tissue-selective SERMs offer a promising avenue for treating conditions that are estrogen-dependent, such as osteoporosis and breast cancer, with greater precision.

8. Digital Health and Patient Monitoring

The integration of digital health technologies, such as mobile health apps and wearable devices, into SERM treatment protocols is an emerging trend. These technologies can help monitor patient adherence to SERM therapies, track side effects, and provide real-time data to healthcare providers for personalized treatment adjustments. Digital tools also empower patients to engage more actively in their treatment, potentially improving outcomes.

9. Global Expansion and Increased Access

The growing awareness of women’s health issues in developing regions is driving the expansion of SERMs into new markets. Pharmaceutical companies are increasingly focusing on expanding the availability of SERMs in emerging markets across Asia, Latin America, and Africa. Efforts to improve access to healthcare and increase awareness about breast cancer prevention and osteoporosis management are supporting this global expansion.

10. Ongoing Clinical Trials and Research

A surge in clinical trials focused on SERMs for new indications is driving innovation in the market. Ongoing research is investigating the role of SERMs in preventing hormone-dependent cancers, treating metabolic syndromes, and even addressing neurodegenerative diseases. As these trials progress, they could open up new therapeutic opportunities and expand the market for SERMs

Access Complete Report - https://www.credenceresearch.com/report/selective-estrogen-receptor-modulators-market

Key Players

Johnson & Johnson

Pfizer, Inc.

Roche Holding AG

Novartis AG

Merck & Co., Inc.

Sanofi

AbbVie Inc.

Takeda Pharmaceutical Company

GlaxoSmithKline plc

Teva Pharmaceuticals

Others

The Selective Estrogen Receptor Modulators (SERMs) market offers several growth opportunities driven by advancements in drug development, increasing demand for hormone-related treatments, and expanding therapeutic applications. Key growth opportunities in the SERMs market include:

1. Expanding Applications Beyond Breast Cancer and Osteoporosis

While SERMs are primarily used for the treatment and prevention of breast cancer and osteoporosis, there are significant opportunities to expand their use in other therapeutic areas. Research is ongoing into their potential applications in treating conditions such as polycystic ovary syndrome (PCOS), endometriosis, cardiovascular diseases, and even certain neurodegenerative disorders. Broadening the scope of SERM usage into these new areas could substantially increase market size.

2. Growing Focus on Women’s Health

The rising global focus on women's health issues, particularly postmenopausal health, presents a major growth opportunity for the SERMs market. As the population of postmenopausal women grows, there is increasing demand for treatments to address conditions such as bone health, breast cancer prevention, and menopausal symptoms. SERMs, with their ability to selectively act on estrogen receptors, are well-positioned to play a key role in addressing these health concerns.

3. Personalized Medicine and Biomarker-Driven Therapies

The development of personalized medicine based on biomarkers and genetic profiling offers a significant growth opportunity. Identifying patients who are most likely to benefit from SERM therapy based on their genetic makeup or hormonal profile can lead to more effective and personalized treatment plans. This approach not only improves patient outcomes but also reduces the risk of side effects, making SERMs a more attractive option for a broader range of patients.

4. Development of Next-Generation SERMs

Pharmaceutical companies have the opportunity to develop next-generation SERMs with improved selectivity and fewer side effects. These newer drugs can offer enhanced tissue selectivity, reducing risks such as thromboembolism and uterine cancer while maintaining therapeutic efficacy in target tissues like bone or breast. This development could expand the use of SERMs and make them more competitive against other hormonal therapies.

5. Combination Therapies

Combining SERMs with other therapies, such as aromatase inhibitors or bisphosphonates, presents an opportunity to create more effective treatment protocols, particularly for breast cancer and osteoporosis. Combination therapies can target multiple pathways involved in disease progression, improving patient outcomes and expanding the therapeutic reach of SERMs. Research into multi-modal treatment strategies is an area ripe for growth.

6. Rising Demand in Emerging Markets

Emerging markets, particularly in Asia-Pacific, Latin America, and Africa, offer substantial growth opportunities for SERMs. As awareness of breast cancer prevention, osteoporosis treatment, and women's health increases in these regions, so does the demand for effective therapies like SERMs. Expanding access to SERMs in these regions through strategic partnerships, regulatory approvals, and distribution networks can significantly boost market growth.

7. Aging Population and Rising Osteoporosis Cases

The aging global population is contributing to a rise in osteoporosis cases, creating a growing need for bone health treatments. SERMs, such as raloxifene, are effective in treating and preventing postmenopausal osteoporosis, offering a significant market opportunity. As healthcare systems focus more on preventive care and management of age-related conditions, the demand for SERMs in osteoporosis treatment is expected to grow.

8. Advances in Drug Delivery Systems

Innovations in drug delivery systems, such as long-acting injectables, oral disintegrating tablets, and transdermal patches, provide growth opportunities by improving patient compliance and convenience. Enhanced delivery methods can reduce dosing frequency, improve bioavailability, and minimize side effects, making SERMs more attractive for long-term use. This is particularly important for chronic conditions like osteoporosis, where patient adherence to treatment is a critical factor.

9. Increased Research in Male Health

There is emerging research exploring the use of SERMs in treating male health issues, such as male hypogonadism and infertility. SERMs have the potential to modulate estrogen activity in men, offering a novel approach to managing these conditions. Expanding the use of SERMs into male health opens up new markets and diversifies the therapeutic applications of these drugs.

10. Government Initiatives and Awareness Campaigns

Government initiatives aimed at promoting cancer prevention and women's health are driving demand for effective treatments like SERMs. Increased public awareness of breast cancer and osteoporosis through campaigns and educational programs encourages early detection and proactive treatment, creating greater demand for SERMs in preventive care. Collaborating with governments and healthcare organizations to expand access to SERMs could accelerate market growth.

11. Growing Interest in Non-Hormonal Alternatives

As more patients seek alternatives to traditional hormone replacement therapy (HRT) due to concerns about risks associated with long-term hormone use, SERMs provide a safer, non-hormonal option. Their ability to selectively target estrogen receptors without the broader hormonal effects of HRT makes SERMs a preferred choice for certain patient populations. Expanding the awareness and use of SERMs as an alternative to HRT presents a growth opportunity, especially for women seeking hormone-free treatments.

12. Collaborations and Licensing Agreements

Pharmaceutical companies can explore collaborations and licensing agreements to expand their product portfolios and market reach in the SERM space. Collaborating with research institutions and biotech firms to develop innovative SERMs or expand into new therapeutic areas can accelerate product development and market entry. Licensing agreements with regional players in emerging markets can also help companies penetrate new geographic markets.

Segmentation

By Indications

Breast Cancer Treatment and Prevention

Osteoporosis Management

Hormone Replacement Therapy (HRT)

By Drug Type

Tamoxifen

Raloxifene

Bazedoxifene

Lasofoxifene

Others

By Gender and Age Group

Women

Men

By Route of Administration

Oral

Injectable

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The Depression Manual

I am guessing I’m like many of you in that I have too much faith in the internet. Faith and lack of motivation that is. I google something, scan the AI explanation and browse the first 5 articles that the search engines deems worthy.  

I google depression a lot. I do this to verify that yes, the last 30 years are correct and my symptoms match. I also look to see if my diagnosis might be more severe and have been afraid that I have any number of personality disorders which I guess makes me neurotic since hypochondria is a type of neuroticism. I am not interested in this new coded way of calling women crazy- ahem neurotic. But here, I digress.

I rest assured that I am like many others and seek more information and in my case always looking for more accurate language to wrap around my experience as someone with recurrent depressive episodes. What I’ve determined is that the info on depression- the detailed info, from the point of view of people who have lived it- is hard to come by.  Instead, we get the health briefs from mayo clinic and NIH about the symptoms of depression and of course the hotline. The symptoms including feelings of sadness and hopelessness, loss of interest in activities you once enjoyed, fatigue/ low energy, sleep disturbances, difficulty concentrating, remembering details and making decisions, physical symptoms like headaches and chronic pain and thoughts of suicide.  A list. Not an article on anything beyond the list besides the mention at the end of the gold star standard treatment of SSRIs and cognitive behavior therapy. On my most recent search I saw an article that contained the regurgitated list and then emphasized self-care for the support person. We beg of you, take cover- I mean, take care of yourself when you are around the depressed person. Let them rot. They are rotting anyway.  These articles aren’t helpful to people who are experiencing the difficulty of not knowing what to do when their person is depressed.

My mom was very good about knowing how to interact with me, handle me during my depressive episodes. She wasn’t always good at it. When the episdoes first showed up in my mid-teens I didn’t know what to do about my personality slipping through my fingers, which is what it always feels like. She didn’t know what to do either and there was a lot of conflict. I wanted out from under the microscope and she wanted me to be OK. Worst. Episode. Ever.

I lost my mom two years ago to uterine cancer treatment complications. She was 73 and had lived a very healthy life. Never smoked cigarettes, drank only the occasional wine or beer, ate food prepared at home. She not only took good care of her body, she also took good care of her mind. She was extremely well read and had a wide array of references across subject matters. Sometimes I would find books in her nightstand stack about mental health. This was a semi-snoop on my part, trying to find out what she was finding out about me. Some of the books were hidden under clothes in her closet. This was a full-on total snoop. These books should be differentiated  from the books she would strategically place in my environment, knowing that I would be more likely to listen to the wisdom of a stranger than my mother. My favorite strategically placed book was titled “Caffeine: the Gateway Drug”.  That was strategically placed around the house after I got in trouble for taking a bunch of Nodoz at an overnight retreat freshman year. In my defense, these retreats were in the context of catholic school so they were dripping with prayer and reflections involving God’s plan.  I think I would have been manic at these retreats anyway.

I only started appreciating her approach when I was older and noticed changes in how she would communicate with me. 

I always feel the void of her absence. I especially feel it when I am struggling and wading through a depressive episode. I get lightning storms in my head when my partner or friends don’t demonstrate the same understanding of how to deal with a depressed person- which I know, is completely unfair. I have been wondering if it’d be worth it to write some sort of depression manual.

I am scared of being overly self-indulgent but in the interest of getting more articles out there from the point of view of someone who lives through depressive episodes, I’d like to contribute. I personally would like to read more articles from people who live with this pesky, devastating, debilitating disorder. 

My Depression Manual

1-AVOID THE MICROSCOPE

 Try not to throw a celebration when I say something little I did in a day that demonstrates “opposite action”, like running on the treadmill or leaving the house. It seems like this would be a nice thing to do but it actually feels condescending and reinforces the invalid state I’ve descended into. I would rather you wait a week or two and then you could say something like “I think it’s really impressive how much you’ve been running on the treadmill.” That would make me feel less like I’m under a microscope or like my loved ones are trying hard to find something positive to say. When I’m doing something that a normal, healthy person would do, like if I fell asleep easily or slept 8 hours, I’d like to have others react as if I’m a normal, healthy person, instead of drawing attention to the fact that the normal, healthy thing is abnormal for me. The pointing out reminds me that I’m different/struggling/ etc

2- THE VULNERABILITY LADDER.

I will share.  I share things.  I am vomiting my feelings and disorganized thoughts all the time.  I get embarrassed at the level of sharing especially when I feel like it’s one sided. So, you need to share too. If you share, then you don’t need to ask as many questions (ugh, too many questions are so irritating) because your sharing invites me to share.  Creating space for me involves a mutual level of vulnerability and trust. Often I share more when the other person puts some vulnerability on the table or if you want to keep it about how my reactions/ emotional states are affecting you, say something about how you have tried X but it doesn’t seem to be working. I often feel stagnant emotional states stir when I feel like someone else needs help or needs me to show up for them.

3- STOP EXPECTING MY BRAIN TO WORK IN THE SAME WAY

Depression interferes with my processing time, verbal speed and executive function. I get exhausted by socializing more easily, this includes phone time. I am working on using phrases that are kind and reflective instead of reactionary to end conversations. For now it might sound something like, “I need to get off the phone” or “I have to go”.  It’s hard not to take it personally but it’s not personal, it’s my capacity reaching overwhelm.  Often I try to hang in there and harangue myself when I don’t feel like I can hang in for long.  When I press myself to stay longer than I’m able it results in clipped, terse responses and acting in a way I don’t want to be, followed by guilt after the interaction due to the way I came across.

4- STOP EXPECTING ME TO BE BRIGHT AND SHINY

I’m sure you’ve heard of masking. We all mask to some extent and mask more during certain periods than others. And yes, of course I’m a little over the trendy mental health term of the past few years: authenticity, but it’s true. Having the ability to show up more authentically allows me to show up at all. If I can be lackluster, smile less, be less talkative, that’s the depression. I feel enormous pressure to somehow put it away and be the person that people know and like- and this leads me to not want to show up at all which leads me to my next point.

5-ISOLATION IS CAUSED BY OVERWHELM

One of my friends ( who has experienced major depression too) said to me that he is happy to come over and not talk, to sit and watch TV or just be in proximity, with no expectations from me. That was some magic my mom would provide- companionship that was gentle and different from the companionship that is possible when I’m not stuck. The isolation thing is something I see listed frequently- posed as advice to the depressed person as something not to do. Don’t isolate, get out, be around people. That is fine advice but it doesn’t deconstruct the why of isolation. Depressed people isolate because socializing is overwhelming, environments outside the home can be overstimulating, overstimulating environments combined with the pressure of socializing is too much. Despite that technically I may not be doing much, I still desire the slowness of being in my home environment.  When I take the instagram psychobabble advice of not isolating and just getting out there I am incredibly self conscious about point #3- that my brain, my words just don’t work in the same way.

6-CONVERSATIONS CAN BE DIFFICULT, SMALL TALK IS TORTURE- I know what you are thinking, small talk is always torture. But I mean really, beyond my brain processing slower with jumbled, disorganized, dark thoughts it’s so hard to work around the typical small talk questions. If we were to play this out with our favorite word to love and hate, authenticity this is what the small talk conversation might look like

Scene featuring: Non-depressed person aka the lucky bastard (LB)

Depressed person (DP)

LB calls DP on the phone because they are kind and supportive and this is a nice thing to do. 

DP stares at phone, feels panic, wants to ignore the call because they are not sure if they have enough energy in their body to speak but doesn’t want to be avoidant, doesn’t want to harm the relationship more than they fear they already have. DP picks up phone

LB: hi! What’s up?

DP: Not much, how are you? 

LB: Oh I’m just heading home from work, it was a really busy day but Carol brought in Schlotsky’s for lunch so that was nice I overslept because I was having the best dream so I think I got over 9 hours of sleep.  How are you?

DP: totally empty inside

LB: aw man, I’m sorry. That sucks. What did you do today?

DP: I woke up after a total of 4 hours of interrupted sleep throughout the night. I laid in bed for an hour contemplating the reason for my existence. My dog needed to be fed so I got up to feed him. I chain smoked 4 cigarettes and had coffee hoping that dosing myself with anxiety would be a sort of energy I could work with. I cried for 30 minutes. I stared at a picture of my mom for a while. I went to the bathroom and tried to convince myself to get in the shower but getting wet has been hurting my skin and making me panic lately so I didn’t. I went to do my TMS treatment and worried that I smelled bad. I came home and sat on the couch and literally stared at the wall for 40 minutes. I tried not to get back in bed but I was so tired that I got back in bed. I rewatched a show that I’ve seen a million times. I looked on instagram and thought about how different I was from people who actually do things. I cried again for a while. I remembered that I had clothes in the washing machine from yesterday morning that smelled musty so I rewashed them. 

LB:Well….that’s a lot of stuff at least. Are you feeling any better than yesterday?

DP: No. I feel the same as I’ve felt for a week which is worse than how bad I was feeling last week which is worse than how I was feeling the week prior to that. 

LB: Can I help in some way?

DP: I don’t really have the neural resources to figure out ways to help you feel like you are helping me. You could come over and sit with me and not touch me and just be in my environment.

LB: Oh I wish I could but I have to pick up the kids and head to their softball game. Another time though. I love you.

DP: Ok. Thank you. I need to get off the phone now. I feel exhausted from this conversation. I hope you don’t hate me because I am a terrible downer. 

LB: I don’t hate you. You’ll feel better soon. Hang in there.

DP: Ok. I will hang in there. Hopefully not literally. I’m sorry. That was a terrible thing to say.

I don’t have anything to share about my day- on the bad days.  I can listen to your day but I’d appreciate acceptance when I say I don’t have much to share. Also would appreciate being able to answer the phone and not feel pressured to “turn it on” and make animated small talk. I’m not going to be as talkative, it’s not personal, it’s just part of it.  I don’t want it called out or told that I’m “not being nice” because I’m not being talkative. Being nice and being talkative are not mutually exclusive, like, at all. Think about that for a second. 

7-RESIST THE TEMPTATION TO GET CLINICAL- I have a team of mental health professionals. I don’t need another one. I don’t need you to suggest various diagnoses, medications, therapy methods or adding magnesium supplements to treat my depression. I have dealt with this for decades, have explored so many paths, there isn’t much you can suggest to me that I haven’t tried. I get offended when people start suggesting things to add into my treatment plan. I need loved ones, not more doctors and therapists.

8- UNDERSTAND THAT EVERYTHING IS EFFORTFUL

And this is just the way it is. Until the clouds start to part and I can have my personality back.

9- I KNOW I WAS A SNOT EARLIER ABOUT SELF-CARE BUT IT IS IMPORTANT, YOU SHOULD DO IT

Take breaks. Do what you need to do to refuel. I feel a ton of guilt about subjecting people to me when I am under water.