#SARS-CoV-2 reports

[rikaklassen]

CW: COVID-19

via @augieray@mastodon.social

Yes, I wish the general public takes COVID more seriously.

Coronavirus is not like the flu nor RSV and we've known about that since MERS and the first SARS. Also, massively disappointed with queer assimilationists since COVID is quite similar to HIV/AIDS and given how the government's eugenicist policies and their anti-LGBT campaigns wiped out many of the people who would have been elders in our communities today. Let's alone the deaf communities with the older generations of sign language folks becoming deaf and multi-disabled because of rubella, which is much more infectious than COVID.

I encourage you to read what Augie has to say since the screenshot is a snapshot of a five-parts thread.

Here is the spreadsheet where Augie took the time to read over 1 500 studies and summarized the findings of about 500 of them: https://docs.google.com/spreadsheets/d/12VbMkvqUF9eSggJsdsFEjKs5x0ABxQJi5tvfzJIDd3U/

[covid-safer-hotties]

Always a good idea to check in with Data Report from time to time

[tornadoquest]

Tornado Quest Top Science Links For June 8 - 15, 2024 #science #weather #climate #tornado #hurricane #drought

Greetings everybody! Thanks so much for stopping by. As severe weather and tornado activity continues, the Atlantic hurricane season is here as well. We’ll continue our overview of severe weather and tornado safety but also get into more details on hurricane preparedness. We also have our look at the latest US Drought Monitor update along with interesting science reads, so let’s get…

[xtruss]

CDC Update After COVID Variant BA.2.86 Detected in U.S.

— August 24, 2023 | Newsweek | By Pandora Dewan, Science Reporter

A man holding up a COVID-19 test. The CDC has issued a warning about new SARS-CoV-2 variant BA.2.86. Daria Nipot/Getty

There have been numerous variants of the SARS-CoV-2 virus so far, including the highly transmissible Omicron strain that made headlines in 2022. However, according to the CDC, the new BA.2.86 has even more additional mutations compared with previously detected Omicron variants.

The large number of mutations raises concerns that the new variant may be more effective at evading our existing immunity to the virus, either through vaccinations or previous infections. However, it is too soon to say how it will impact global immunity, as samples are not yet broadly available for lab-based antibody testing.

"Nearly all the U.S. population has antibodies to SARS-CoV-2 from vaccination, previous infection, or both, and it is likely that these antibodies will continue to provide some protection against severe disease from this variant," the CDC said. "This is an area of ongoing scientific investigation."

Only nine cases of the new strain have been confirmed so far: three in Denmark; two in South Africa; one in Israel; two in the U.S.; and one in the U.K. However, the variant has also been detected in U.S. waste-water samples.

With such a small number of confirmed cases, it is too soon to know how transmissible the new variant is, although its detection across multiple continents does indicate some degree of transmissibility.

The severity of disease caused by BA.2.86 is also unclear. "At this time, locations where this variant have been detected have not experienced increases in transmission indicators (e.g., cases, emergency department visits) or hospitalizations out of proportion to those seen in neighboring locations," the CDC said. "However, it is early in the emergence of this variant and too soon to evaluate impacts based on these indicators."

The good news is that, from what we know so far, the existing detection tests and medications used to treat COVID-19 appear to be effective against this new variant.

There are a lot of unknowns surrounding BA.2.86, but to stay safe, the CDC recommends the following actions:

Stay home if you are sick.

Get tested for COVID-19 if you feel flu-like symptoms.

Improve ventilation.

Wash your hands.

Get vaccinations as recommended by your health provider.

— Pandora Dewan is a Newsweek Science Reporter based in London, UK. Her focus is reporting on science, health and technology. Pandora joined Newsweek in 2022 and previously worked as the Head of Content for the climate change education start-up, ClimateScience and as a Freelance writer for content creators such as Dr Karan Rajan and Thoughty2. She is a graduate in Biological Sciences from the University of Oxford.

[thoughtportal]

The study found that compared to short-haul flights without enforced masking, long-haul flights with no strict masking had a 25.93-fold increase in COVID-19 incidence rates, while medium-haul flights had a 4.66-fold higher incidence rate. However, long-haul flights where masking was enforced reported no transmission of SARS-CoV-2, indicating that masking could significantly lower aircraft-acquired COVID-19.

Furthermore, in flights with unenforced masking, each hourly increase in flight duration increased the transmission incidence rate by 1.53-fold. The reduced duration of exposure to aerosols and the non-inclusion of meals make shorter flights safer since they lower the probability of expelling aerosol particles or coming in contact with them.

The study also found that long-haul flights with enforced masking had almost no reports of SARS-CoV-2 transmission within the aircraft despite meals being served. The researchers believe the enforced masking could have caused the passengers to eat as quickly as possible. Furthermore, enforced masking also allows the flight attendants to ensure that passengers are appropriately masked.

[submalevolentgrace]

From the earliest days of the COVID-19 pandemic, scientists have raised concerns about the potential for long-term health problems linked to SARS-CoV-2 and warned repeated infections are likely to increase the risk. An association between COVID and cardiovascular disease emerged quickly. And now — almost exactly four years since the first case was discovered in Wuhan — a growing body of scientific research is cautiously linking the inflammation caused by a COVID infection to diseases like Alzheimer's and Parkinson's as well as autoimmune conditions from bowel disease to rheumatoid arthritis. The virus has even been suggested to impact some pregnant women, associated with double the risk of premature delivery. As the eighth COVID wave hits Australia, experts are taking notice.

...

When the first wave of COVID patients began reporting loss of smell and taste, Barnham's radar went up. "Any time you see olfactory impairment it tells you that there's going to be neurological impact," he says. "Loss of smell is a cardinal, pre-clinical symptom of Parkinson's disease and it's been implicated in Alzheimer's disease as well." The fact that COVID patients reported loss of smell not only during the active phase of the disease, but as a persistent symptom, suggested to Barnham that longer-term health consequences were likely. Loss of smell is associated with loss of brain volume.

[tzifron]

Worldwide, there were more than 11,000 reported deaths from COVID between mid-December 2023 and mid-January 2024, and more than half of those deaths occurred in the U.S. In that same time frame, nearly one million cases were reported to the World Health Organization globally (although reduced testing and reporting means this is likely a vast undercount). In particular, epidemiologists are monitoring the newest variant of SARS-CoV-2, JN.1, and looking for any signs that it may be more severe than previous strains.

Although the WHO declared an end to the COVID public health emergency in May 2023, the organization has emphasized that the pandemic isn’t over—it’s just entered an endemic phase, which means that the virus will continue to circulate indefinitely.

[...]

How would you describe the overall state of COVID at this point in the pandemic?

COVID’s not in the news every day, but it’s still a global health risk. If we look at wastewater estimates, the actual circulation [of SARS-CoV-2] is somewhere between two and 20 times higher than what’s actually being reported by countries. The virus is rampant. We’re still in a pandemic. There’s a lot of complacency at the individual level, and more concerning to me is that at the government level.

[...]

"We understand you don’t want to hear about it. I don’t want to talk about it. But we need to because there’s more we can do. We cannot prevent all infections. We cannot prevent all deaths. But there’s a hell of a lot more that we can do to keep people safe and save them from losing a loved one"

[mindblowingscience]

A monoclonal antibody appears effective at neutralizing the numerous variants of SARS-CoV-2, as well as related viruses in animals that could pose a threat if they were to begin spreading in people. The antibody, called SC27, was recently described in an article published in Cell Reports Medicine. The finding opens the possibility of broader, more effective treatments to work against current and future COVID variants.

Continue Reading.

[covid-safer-hotties]

Orange County Florida showing highest rates of covid in wastewater since monitoring began and rising. This is higher than their omicron peak. "The pandemic is over."

[lotus-tower]

COVID-19's long-term effects on the body: an incomplete list

COVID’s effect on the immune system, specifically on lymphocytes:

NYT article from 2020 (Studies cited: https://www.biorxiv.org/content/10.1101/2020.05.18.101717v1, https://www.biorxiv.org/content/10.1101/2020.05.20.106401v1, https://www.unboundmedicine.com/medline/citation/32405080/Decreased_T_cell_populations_contribute_to_the_increased_severity_of_COVID_19_, https://www.medrxiv.org/content/10.1101/2020.06.08.20125112v1)

 https://www.biorxiv.org/content/10.1101/2022.01.10.475725v1

https://www.science.org/doi/10.1126/science.abc8511 (Published in Science)

 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057012/

https://www.forbes.com/sites/williamhaseltine/2022/04/14/sars-cov-2-actively-infects-and-kills-lymphoid-cells/

https://www.cleveland.com/news/2022/10/in-cleveland-and-beyond-researchers-begin-to-unravel-the-mystery-of-long-covid-19.html

SARS-CoV-2 infection weakens immune-cell response to vaccination: NIH-funded study suggests need to boost CD8+ T cell response after infection

https://www.merckmanuals.com/professional/hematology-and-oncology/leukopenias/lymphocytopenia

https://thetyee.ca/Analysis/2022/11/07/COVID-Reinfections-And-Immunity/

Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1034159/full

https://www.n-tv.de/politik/Lauterbach-warnt-vor-unheilbarer-Immunschwaeche-durch-Corona-article23860527.html (German Minister of Health)

Anecdotal evidence of COVID’s effects on white blood cells:

 https://twitter.com/DrJohnHhess/status/1661837956875956224

 https://x.com/TristanVeness/status/1661565201345564673

https://twitter.com/TristanVeness/status/1689996298408312832

Much more if you speak to Long Covid patients directly!

Related information of interest:

China approves Genuine Biotech's HIV drug for COVID patients

COVID as a “mass disabling event” and impact on the economy:

https://www.ctvnews.ca/health/report-says-long-covid-could-impact-economy-and-be-mass-disabling-event-in-canada-1.6306608

https://x.com/inkblue01/status/1742183209809453456?s=20

COVID’s impact on the heart:

https://www.dailystar.co.uk/news/world-news/deadly-virus-could-lead-heart-31751263 (Research from: Japan's Riken research institute)

https://www.brisbanetimes.com.au/national/queensland/unlike-flu-covid-19-attacks-dna-in-the-heart-new-research-20220929-p5bm10.html

https://www.mdpi.com/2077-0383/12/1/186

https://medicalxpress.com/news/2023-04-mild-covid-effects-cardiovascular-health.html

https://publichealth.jhu.edu/2022/covid-and-the-heart-it-spares-no-one

https://www.bhf.org.uk/informationsupport/heart-matters-magazine/news/coronavirus-and-your-health/is-coronavirus-a-disease-of-the-blood-vessels (British Heart Foundation)

COVID’s effect on the brain and cognitive function:

https://www.openaccessgovernment.org/article/brain-infection-by-sars-cov-2-lifelong-consequences/171391/

https://www.cidrap.umn.edu/covid-19/study-shows-covid-leaves-brain-injury-markers-blood

https://www.theguardian.com/world/2020/jul/08/warning-of-serious-brain-disorders-in-people-with-mild-covid-symptoms

Cognitive post-acute sequelae of SARS-CoV-2 (PASC) can occur after mild COVID-19 

Neurologic Effects of SARS-CoV-2 Transmitted among Dogs

https://journals.lww.com/nsan/fulltext/2022/39030/neurological_manifestations_and_mortality_in.4.aspx

https://www.salon.com/2023/06/17/new-evidence-suggests-alters-the-brain--but-the-extent-of-changes-is-unclear/

https://www.scientificamerican.com/article/covid-virus-may-tunnel-through-nanotubes-from-nose-to-brain/

https://neurosciencenews.com/post-covid-brain-21904/

https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(22)00260-7/fulltext

https://medicalxpress.com/news/2022-08-covid-infection-crucial-brain-regions.html

https://news.ecu.edu/2022/08/04/covid-parkinsons-link/

Covid as a vascular/blood vessel disease:

https://www.salon.com/2020/06/01/coronavirus-is-a-blood-vessel-disease-study-says-and-its-mysteries-finally-make-sense/

https://www.salon.com/2023/12/27/brain-damage-caused-by-19-may-not-show-up-on-routine-tests-study-finds/

https://www.nih.gov/news-events/news-releases/sars-cov-2-infects-coronary-arteries-increases-plaque-inflammation

https://www.mdpi.com/2077-0383/12/6/2123

https://www.sciencedaily.com/releases/2021/10/211004104134.htm (microclots)

Long Covid:

Post-COVID-19 Condition in Canada: What we know, what we don’t know, and a framework for action

 https://www.ctvnews.ca/health/coronavirus/more-than-two-years-of-long-covid-research-hasn-t-yielded-many-answers-scientific-review-1.6235227

 https://www.cbc.ca/news/canada/london/cause-of-long-covid-symptoms-revealed-by-lung-imaging-research-at-western-university-1.6504318

 https://www.cbc.ca/news/canada/montreal/long-covid-study-montreal-1.6521131

https://news.yale.edu/2023/12/19/study-helps-explain-post-covid-exercise-intolerance

Other:

- Viruses and mutation: https://typingmonkeys.substack.com/p/monkeys-on-typewriters

Measures taken by the rich and world leaders

Heightened risk of diabetes

https://jamanetwork.com/journals/jama/fullarticle/2805461

https://www.nature.com/articles/d41586-022-00912-y

Liver damage:

https://timesofindia.indiatimes.com/city/mumbai/46-of-covid-patients-have-liver-damage-study/articleshow/97809200.cms?from=mdr

tl;dr: covid is a vascular disease, not a respiratory illness. it can affect your blood and every organ in your body. every time you're reinfected, your chances of getting long covid increase.

avoid being infected. reduce the amount of viral load you're exposed to.

the gap between what the scientific community knows and ordinary people know is massive. collective action is needed.

[pandemic-info]

COVID patients breathe large amounts of virus early on - Northwestern Now

It is the first longitudinal, direct measure of the number of SARS-CoV-2 viral copies exhaled per minute over the course of the infection — from the first sign of symptoms until 20 days after. On day eight, exhaled levels of virus drop steeply, down to near the limit of detection — an average of two copies exhaled per minute. Northwestern investigators tested breath samples — collected multiple times daily from 44 individuals — over the entire course of infection to determine when a person is most infectious.

...

“The vast majority of research on viral loads over the course of a COVID-19 infection has been based on nasal or oral swabs, which measure virus in the nose or throat,” said lead study author Gregory Lane, senior research project manager in Zelano’s lab. “However, SARS-CoV-2 is spread through breath, and virus on the breath may not match virus in the nose. The dynamics of viral shedding on breath over the course of infection are poorly understood, despite the fact that this is how the virus spreads.”

See also:

[willowreader]

We desperately need a vaccine that works for all variants.

[ricisidro]

SARS-COV-2 PCR percent positivity during the four-week reporting period from 24 June to 21 July 2024, increased from 7.4% in the beginning week of the reporting period to 13.0% in the last week across 85 countries.

Globally, JN.1 is the most reported variant of interest (VOI), accounting for 25.7%.

The number of new cases and deaths increase by 30% and 26% compared to the previous 28-day period. Over 186,000 new cases with more than 2,800 new fatalities reported.

As of 21 July 2024, over 775M confirmed cases and more than 7M deaths have been reported globally since the beginning of pandemic. 

https://www.who.int/publications/m/item/covid-19-epidemiological-update-edition-170

[feminist-space]

"Most of what “public health” does for Americans is taken for granted. Before the Covid pandemic, most people probably didn’t think about it at all. Yet the fact that, in most places in the United States, we can count on the water we drink to be safe, that the food we buy is not contaminated with e-coli or listeria, and that we don’t have to deal with dreaded childhood diseases that ripped through our communities only a few decades ago, is a testament to the tireless work of many, unheralded, often unknown heroes. This invisible safety net has been built up over the years, always underfunded and understaffed, always not-enough, but it’s all we’ve got.

...

By now, we’ve heard Kennedy’s views on everything from fluoride in drinking water to childhood vaccines, to threats to recreate the NIH and FDA in the image of his own quackery. Let’s be clear: Kennedy’s views are not “alternative” to orthodoxy, meant to shake up the system—they are verifiably false. They are nonsense.

Let’s take his claims on fluoride as an example. RFK Jr. wrote on X in early November: “Fluoride is an industrial waste associated with arthritis, bone fractures, bone cancer, IQ loss, neurodevelopmental disorders, and thyroid disease.” Um—no. In high doses over prolonged periods of time—as with many other substances (even water and oxygen!)—exposure to fluoride can be a problem, but not in the small concentrations we see in drinking water. Lest we forget: Fluoride has been a bugaboo of the far right since the 1950s, when fluoridation was supposed to be part of a communist plot to take over America.

And since conspiracy theories know no borders, we can also look at a natural experiment up in Calgary, Canada, for further evidence. In 2011, Calgary’s’s city council banned fluoridation, and now is set to reintroduce it next year. Why? Because since fluoridation ended, cavities in children’s teeth have become more numerous and larger, often requiring treatment under general anesthesia and/or intravenous antibiotic therapy to fight infections associated with tooth decay. As one researcher at the University of Calgary has said, the decision to ban fluoridation had a clear result: It was a source of ���avoidable and potentially life-threatening disease, pain, suffering, misery and expense…especially [for] very young children and their families.”

As for vaccination, Kennedy’s views are long-standing and well-known. He has suggested that “there is no vaccine that is safe and effective,” and he still clings to the long-debunked idea that vaccines cause autism. More recently, during the Covid pandemic, he created a multimillion-dollar anti-vaccine juggernaut to dissuade people from getting vaccinated against SARS-CoV-2.

There is no person right now more vital to the anti-vaccine movement than RFK Jr., and his impact has been deadly. By convincing people to forgo routine pediatric vaccinations, he has endangered the lives of thousands of kids, stoked fear in families with autistic children, and in at least once instance was partially responsible for a devastating outbreak of measles. In 2019, 83 people, mostly children, died of the preventable disease in Samoa. While Kennedy has denied that his words and actions were responsible for the outbreak, he has supported anti-vaccination efforts on the islands, written to the nation’s prime minister about the dangers of vaccines, and visited Samoa to meet with anti-vaxxers and subsequently praised them for their work. As Derek Lowe, a columnist from the United States’ leading scientific journal, Science, has said: “Kennedy’s views on science and medicine are not only wrong, they are actively harmful and destructive. He has used them to make a great deal of money, and he has lied about them to interviewers and reporters whenever he finds it convenient.”

...

RFK Jr. is the poster boy for the new Trump administration, a rich man who never has had to worry about a thing in his life, putting the lives of ordinary Americans in jeopardy because he thinks he knows better than scientists. In fact, the man who thought it was a good idea to stage a hit-and-run with a dead baby bear and a bicycle in Central Park has shown a lack of judgment across the board for a long while. But he is part of an emerging kakistocracy-in-waiting that will be run by plutocrats and zealots. Our public health system in America is fragile and shouldn’t be a plaything. Once he’s done with his games, all the king’s horses and all the king’s men may not be able to put our public health infrastructure back together again. The damage may be lasting and profound.

But we are not powerless. So much of public health happens locally—and we can protect this precious national resource by speaking up and speaking out, at our city or town council meetings, calling and writing our state representatives, our mayors and our governors. This is going to be necessary work. As my Yale colleague Timothy Snyder has said: “Defend institutions.… Institutions do not protect themselves. So choose an institution you care about and take its side.” This may be your local public health department or Planned Parenthood clinic, a mental health clinic or needle exchange program, or services for LGBTQ+ or immigrant populations in your neighborhood.

These are all part of what makes public health happen day in and day out in our communities. Deprive RFK Jr. and Donald Trump of their power; take it away from them with focus and tenacity. Chip away at their campaign to destroy public health in America. These kinds of small acts will add up and will make a difference. If these men are the disease, let us be the cure."

[littlegreenwyvy]

You have covid

"I'm sure it's just a flu"

Flu:

Covid:

"I tested negative for covid"

"It's not so bad cuz hardly anybody dies of covid anymore anyway"

(Note, this ^ study's scope was for the 'core' of the pandemic (I.e. the first 2-3 years), but still has implications today)

"I'm young and healthy so I don't have to worry"

Take covid seriously, or else

Sources:

[kira-akira]

Bernie Sanders Introduces Long COVID Moonshot Legislation

This legislation "provides $1 billion in mandatory funding per year for 10 years to the National Institutes of Health (NIH) to support Long COVID research, the urgent pursuit of treatments, and the expansion of care for patients across the country." Announcement on Sander's twitter and the Long COVID Moonshot website.

This announcement references the number 22 million for adults affected by Long COVID in the US but that number is certainly much higher; in 2022 the CDC reported that 7.5% of US adults have Long COVID and that number can only have increased.

Here is an article published today on PBS if you need a primer or a refresher on what Long COVID is and why everyone needs to care about it. From the article:

"Long COVID is a complex chronic condition that can result in more than 200 health effects across multiple body systems. These include:

Heart disease

Neurologic problems such as cognitive impairment, strokes and dysautonomia. This is a category of disorders that affect the body’s autonomic nervous system – nerves that regulate most of the body’s vital mechanisms such as blood pressure, heart rate and temperature.

Post-exertional malaise, a state of severe exhaustion that may happen after even minor activity — often leaving the patient unable to function for hours, days or weeks

Gastrointestinal disorders

Kidney disease

Metabolic disorders such as diabetes and hyperlipidemia, or a rise in bad cholesterol

Immune dysfunction"

I know it's easy to give into despair but THERE IS HOPE for the future! For decreasing transmission of COVID-19, for developing preventatives against Long COVID, and for treating Long COVID. To highlight just a few of the possible pathways to prevention and treatment being currently researched:

The possibility of using antivirals to treat not just Long COVID but any autoimmune disease

The development of N95 masks that can sense SARS-CoV-2 in exhaled breath using a printed immunosensor

A nasal vaccine that halts transmission of SARS-CoV-2 (though does not stop the user from developing COVID-19)

A Japanese research team is looking to treat COVID-19 by using embryonic stem cells to target the virus

The possibility of using already-developed arthritis drugs to treat Long COVID respiratory symptoms

Researchers just identified a possible protein to target in treating Long COVID fatigue

This is an incredibly small collection of studies researching potential treatments but they themselves and the decades of research they are built on had to be funded. In fact, since the pandemic began, more than 24,000 scientific publications about COVID-19 have been published, making it the most researched health condition in any four years of recorded human history.

So there is hope! But all this research needs money. Money that Long COVID Moonshot will provide. And while we wait for research to bear fruit, that $1 billion per year will also be crucial in caring for those suffering from Long COVID in the meantime.

So What Can You Do?

Keep masking - We've just hit 900,000 new COVID cases per day in the US and this wave is not even at its peak yet (For reference, Fauci stated back in 2021 that getting under 10,000 cases per day would allow for mask mandates and safety measures to relax...)

Go on the Long COVID Moonshot website and write to your legislators in support (You can use their script, it only takes 1 minute!)

Keep yourselves and others informed - On the Moonshot website they also offer handy graphics and facts sheets that you can post wherever you can. Spread the word!

And if you or someone you know has Long COVID, you can write in to the Long COVID Moonshot website about your experience

And remember, no one is safe from Long COVID; your chances of developing Long COVID increase with every reinfection. Until research like what Long COVID Moonshot will fund discovers viable preventatives and treatments, the only way to not get Long COVID is to not get COVID-19 in the first place.

Stay safe, stay hopeful, support Long COVID Moonshot, and mask up!