#Pushpa 2 Review News

[rightnewshindi]

मुकेश खन्ना ने किया पुष्पा 2 का रिव्यू, कहा, अल्लू अर्जुन को करना चाहिए शक्तिमान का रोल

Pushpa 2 Review: मुकेश खन्ना अपने यूट्यूब चैनल पर अक्सर करंट टॉपिक्स पर विचार रखते हैं। अब उन्होंने एंटरटेनमेंट इंडस्ट्री की सनसनी पुष्पा2 का रिव्यू किया है। मुकेश खन्ना अल्लू अर्जुन से इतने इम्प्रेस्ड हैं कि उन्हें शक्तिमान का रोल करते हुए भी देखना चाहते हैं। मुकेश खन्ना ने बॉलीवुड पर तंज कसा और साउथ इंडस्ट्री की तारीफ भी की। अल्लू बन सकते हैं शक्तिमान मुकेश खन्ना जल्दी किसी से इम्प्रेस नहीं…

[lyricsolution-com]

Pushpa 2: The Rule Makes History With ₹294 Cr Worldwide Day 1, Biggest Opening In Indian Cinema | Regional News

Pushpa 2: The Rule Box Office: Allu Arjun starrer creates history at the box office! Grosses 294 Cr. worldwide on day 1, registering highest opening day in Indian cinema. With the release of Pushpa 2: The Rule yesterday, Pushpa’s dominance has officially begun. With exceptional word-of-mouth buzz, the hype for the film has reached an entirely new level across the nation. Garnering rave reviews,…

[bigtvtechman]

All About Pushpa-2 | Pushpa 2 the rule Movie Review | Allu Arjun | Rashmika @chotanewsofficial

All About Pushpa-2 | Pushpa 2 the rule Movie Review | Allu Arjun | Rashmika @ChotaNewsOfficial #pushpa2 #pushpa2therule #pushparaj #pushpamoviereview #alluarjun #chotanews #chotanewstelugu Chotanews Telugu Short News APP ChotaNews is a premier news reading app tailored specifically for those seeking Telugu news updates. it’s dedicated to delivering the latest updates in politics ,Entertainment ,…

[news365timesindia]

[ad_1] Pushpa 2 The Rule review and release live updates: Director Sukumar’s follow-up to Pushpa: The Rise is all set to set fire to the box office. The movie stars Allu Arjun, Rashmika Mandanna and Fahaadh Faasil. Allu is set to return as labourer-turned-sandalwood smuggler Pushpa Raj in the sequel to 2021’s Telugu blockbuster. Rashmika plays his wife, Srivalli. The tickets for the premiere show of Pushpa 2 on December 4 are priced at ₹944 (including GST) at select theatres. According to online ticketing website BookMyShow, the movie has become the fastest movie to surpass the one million tickets sold on the platform, crossing previous records set by Kalki 2898 AD, Bahubali 2 and KGF 2. The film, like many hits from the south in recent years which have broken new grounds in Hindi speaking belt, is likely to cross over ₹60 crore on day one in the north and the crowd frenzy that its trailer launch attracted in Patna was only a glimpse of the buzz surrounding the release. [ad_2] Source link

[news365times]

[ad_1] Pushpa 2 The Rule review and release live updates: Director Sukumar’s follow-up to Pushpa: The Rise is all set to set fire to the box office. The movie stars Allu Arjun, Rashmika Mandanna and Fahaadh Faasil. Allu is set to return as labourer-turned-sandalwood smuggler Pushpa Raj in the sequel to 2021’s Telugu blockbuster. Rashmika plays his wife, Srivalli. The tickets for the premiere show of Pushpa 2 on December 4 are priced at ₹944 (including GST) at select theatres. According to online ticketing website BookMyShow, the movie has become the fastest movie to surpass the one million tickets sold on the platform, crossing previous records set by Kalki 2898 AD, Bahubali 2 and KGF 2. The film, like many hits from the south in recent years which have broken new grounds in Hindi speaking belt, is likely to cross over ₹60 crore on day one in the north and the crowd frenzy that its trailer launch attracted in Patna was only a glimpse of the buzz surrounding the release. [ad_2] Source link

[insideboxofficeindia]

InsideBoxOffice: Pushpa 2 Advance Booking and KGF 2 Hype Comparison

After Pushpa 2 The Rule Advance booking started in the overseas markets, Inside Box Office has constantly provided all major updates through its website and social media handles. Pushpa 2: The Rule breaks US records but most importantly is targeting records in other regions too.  We will do detailed stories on Pushpa 2: The Rule box office record(s) which will cover all the records it has broken in India and overseas. Talking about Pushpa 2: The Rule Budget and Expectations, the budget is massive as Icon Star Allu Arjun’s fee itself is huge and the expectations are also very high to due popularity of the character Pushpa and its dialogues and music. You’ll see KGF Chapter 2 vs Pushpa 2 everywhere because in terms of hype, this is one of the most hyped sequels since KGF 2. Is Pushpa 2 The Rule Hype more than KGF 2 hype? We will find that out. At Inside Box Office, all analysis is made on the basis of data.

There has been a change in hype as Pushpa 2 release date earlier was 15th August but later got changed to 6th December and then finally 5th December. Later, 15th August was blocked by Bollywood Movies: Stree 2, Vedaa and Khel Khel Mein. While Stree 2 became an All Time Grosser, the other two flopped badly despite having John Abraham and Akshay Kumar. Pushpa 2 ticket price(s) are also expected to be high as the film is also releasing in IMAX and 3D. But, the ticket prices in B and C centres are going to be moderate, confirms a credible source from the Inside Box Office team. Allu Arjun’s Pushpa 2 Movie Pre-Booking Sale started off well and with 10 days to go for release it has started setting new benchmarks at the ticket counters.

Pushpa 2 Release date in USA is 4th December where Pushpa 2 The Rule is targeting the biggest premiere for an Indian Movie in America which is now held by Prabhas and Deepika Padukone starrer Kalki 2898 AD. Pushpa 2 movie budget is high but so are the recoveries and because it is an expensive affair it needs to win appreciation and score really big numbers in circuits.

Pushpa 2 the rule Tollywood movie Pre-Sales in UAE started off well and but the pre sales of Pushpa 2 in other Gulf countries needs to pick up as only $50K pre-sales have been done so far where 80% is coming from one major chain VOX in UAE. Pushpa 2 movie advance ticket sale in Germany has been phenomenal where it has crossed lifetime business of various Tollywood and Indian films by selling 2000+ tickets for the opening weekend which has an estimated gross of 42,000+ Euros. Pushpa 2 the rule movie Hype did not pickup as much as KGF Chapter 2 because Pushpa 2 Movie Trailer Review(s) have been mixed whereas for KGF Chapter 2 it was very positive. Pushpa 2 The rule Upcoming Movie songs have also not garnered much love whereas for Pushpa The Rise the appreciation for music was there.  Inside Box Office will cover Pushpa 2 movie Records and share advance booking updates from time to time. Pushpa 2 Movie Advance Ticket Booking in India is expected to begin towards the end of November after the release of the new Pushpa 2 Trailer. Cast of Pushpa 2 the rule includes Allu Arjun, Fahadh Faasil and Rashmika Mandanna and the movie actors have their own fan bases. Pushpa 2 Pre Sale Booking in Australia has also been good where Australia’s main chain HOYTS has put up pre-sales of A$115K+ across all languages and is set for a massive start.

[24hrsallnews]

Singham Again has been rescheduled to release on Diwali, while Stree 2 will release on August 15 alongside Pushpa 2

We will read about, "Singham Again has been rescheduled to release on Diwali, while Stree 2 will release on August 15 alongside Pushpa 2." Prepare yourself for an extraordinary cinematic showdown that will undoubtedly delight all film enthusiasts. Although earlier there was supposed to be a super clash between Pushpa 2 and Singham Returns, but now the release date of Singham Returns has been postponed.  

Singham Again has been rescheduled to release on Diwali

Singham Again is a much awaited, multi-starrer and high budget film which was earlier scheduled to release on 15th August 2024, now its release date is shifted to Diwali. Numerous updates and footage of Singham again are circulating widely once more, intensifying the level of excitement, buzz, and enthusiasm to its pinnacle. There are rumours of Pushpa 2 and Singham releasing dates being postponed again, but Pushpa 2 has not postponed its release date. The last 2 installemnt of Bhool Bhulaiyaa have proved to be superhits. Fans are looking very excited after the update of the cast in the Bhool Bhulaiyaa 3. Both movies have a substantial budget and each one has a highly anticipated sequel, but Singham will again have to face clash with Kartik Aryan in Bhool Bhulaiyaa 3. Kartik Aaryan and Tripti Dimri play the main roles in Bhool Bhulaiyaa 3. Image credit: Twitter (X) Stree 2 will release on August 15 Stree 2 is one of the most awaited film which is the third installment of Maddock Supernatural Universe. Stree 2 was earlier scheduled to release on August 30 but now it has been postponed to August 15, 2024. The highly anticipated release of Maddock Supernatural Universe is scheduled for June 7, 2024, and it is already making waves in the film industry with its remarkable success at the box office. The unique blend of horror and comedy impressed audiences and left them wanting more. The first sequel of 'Stree' had made a great collection at the box office. When Stree 2 opens on August 15th, it will have to compete with a major motion picture. The cast of Stree 2 are Shraddha Kapoor, Rajkumar Rao, Pankaj Tripathi, Naveen Singh, Abhishek Banerjee and others. With such a pool of talent, Stree 2 promises to be a visual entertainer, with performances that will leave you spellbound.

Image credit: @johnabrahament Box Office Clash on 15th August 2024 Movie enthusiasts will be delighted to know that a blockbuster is set to hit theaters on August 15th, promising an exciting experience at the box office. On August 15, Stree 2 will face a clash with Pushpa 2, Khel Khel Mein, Vedaa. Pushpa 2 is a high budget film, a sequel to the blockbuster film Pushpa: The Rise. Allu Arjun is a pan-India star with a fan base that is seen across the globe. Khel Khel Mein, featuring Akshay Kumar, and Veda, starring John Abraham, are scheduled to hit the theaters simultaneously. All four movies belong to distinct genres, allowing fans to enjoy films from various genres according to their preferences. The film Khel Khel Mein is an official remake of the Italian comedy-drama Perfect Strangers. Vedaa is the story of a young woman who struggled, guided and supported by the man she considered her protector, who became her weapon. Prepare yourself for an exceptional movie-watching experience. Mark 15th August on your calendar to see a new clash and see who will win the box office and whose film will dominate the box office.   Read More - The film Luv You Shankar, starring Shreyas Tanisha Mukherjee, has officially released. - The ultimate guide to Tillu Square: A must-watch film for romantic crime comedy fanatics - Psychological thriller Kartam Bhugtam is set to hit the big screen on May 17, 2024, showcasing the concept of karma and its repercussions. - Bhaiyya Ji Movie Review: Manoj Bajpayee explores his foray into the realm of mass hero genre. - Top 10 highest paid actor in India 2024 - Rebel star Prabhas wishes director Prashanth Neel on his birthday with this unseen candid click from the sets of Salaar - HBD Nikhil Siddhartha: Team Swayambhu wishes a very happy birthday to the young and extremely talented Nikhil - Varun Sandesh's suspenseful thriller, Nindha, will be released in cinemas on June 21st. - Gurmeet Choudhary in an all action avatar in Commander Karan Saxena - The new release date for Jr. NTR's flick Devara is confirmed - Announcement of 'Border 2': Sunny Deol shared a video, wrote- A soldier is coming to fulfill his 27 year old promise Read the full article

[telugumovienews]

Telugu movies are not only doing well in the country but also abroad. While 'RRR' is already heading towards an all-time record with sensational collections in Japan, now 'Pushpa: The Rise' is preparing to show its strength in Russia.

Allu Arjun and Rashmika Mandanna's Pan India movie 'Pushpa: The Rise' directed by Sukumar was released in December last year and received sensational success. It is releasing in Russia on December 8 after a year. Bunny, Sukumar and Rashmika went to Russia as part of this movie promotions. They received a warm welcome there. They will attend the special premieres in Moscow on December 1 and St. Petersburg on December 3. It remains to be seen how the film will fare in Russia on December 8. For more information visit Teluguone.com official website

[feralseraph]

“Journalist Emily Clark visited a cashew nut processor in southern India where shellers reported painful injuries caused by cardol and anacardic acids that lie between the two layers of hard shell on a cashew nut. Some 500,000 people work in India’s cashew nut industry – nearly all women – who are paid as little as £2 a day for the arduous labour with no contracts, no guarantee of steady income and no pension or holiday pay. Many of the women were not given gloves and those that were chose not to wear them as it slowed their work down – they are paid by volume. One nut sheller, Pushpa Gandhi, 30, told the newspaper she is covered in scars from her work shelling cashews but makes just 200 rupees a day, or £2.15. ‘Today when we go home and wash, we will see the boils on our skin. It takes about a week for them to heal. But as the old ones heal, new ones keep coming,’ she said. The charity Traidcraft Exchange blames the poor working conditions on European buyers — including UK supermarkets — they claim ‘aggressively push down prices’, forcing cashew companies to hire cheap labour. Nurse Uma Jayamurthi told the paper she was seeing increasing numbers of patients in the past year who have chopped off the top of a finger.

[...]

But it’s not as simple as boycotting the nut altogether, as the millions of cashew workers around the world rely on keeping their jobs. Instead calls have been made to supermarkets to review their supply chains and make sure workers are being paid a fair wage. All major UK supermarkets, including Sainsbury’s, Asda and Tesco, have voluntarily signed up to the Ethical Trading Initiative (ETI) to ensure safe and hygienic working conditions, no child labour, living wages and regular employment is guaranteed to suppliers around the world. But Fiona Gooch, of Traidcraft Exchange, says producers ‘are under too much [price] pressure’ to comply with the agreements. She says finance experts should cross-check wage slips with a sample of workers, and supermarkets should send health and safety teams to inspect factories.“

[latestmovienewsupdates]

Get to Know Latest News about Tollywood Updates

Tollywood News: Nowadays, reading regular news became one of the best parts of our daily life. Also, it is a good habit for people to know about the latest news updates on everything. For this, HYD7AM is the best news-providing site in India. These Websites provide Telangana and Andhra Pradesh news like technical news, Political news, Tollywood Movies reviews, Health & Fitness News…etc.

Waltair Weerayya: Megastar Chiranjeevi's Waltair Veeraya is his upcoming film under the direction of Bobby and produced by Mythri Movie Makers. Recently, the film's teaser was released which gives a positive response from the audience. Now it’s time for the musical promotions. The film first single will going to release on the 23rd of this month at 4:05 PM. To make this announcement the maker released the poster where the megastar can be seen in a mass get-up in a lungi and sparkling shirt performing a graceful step alongside the dancers. In this movie, Ravi Teja also plays a powerful role. And the movie is all set to release during Sankranthi.

Read: Megastar Chiranjeevi Latest News Updates

Kushi: It is known that heroes Vijay Devarakonda and Samantha are pairing up for a mature love story film, titled ‘Kushi’ which is written and directed by Shiva Nirvana. According to the latest buzz, in this film for the special role, the Tamil actor ‘Madhavan’ will play this key role in the second half. but there is no official announcement on this news. If this is true. Let's see how Madhavan's role will be between Vijay Deverakonda and Samantha.

Read: Vijay Devarakonda Latest News Updates

Hit 2: Tollywood talented hero Adivi Shesh’s next upcoming action thriller film titled Hit 2 is a sequel to Hit which is directed by Prashanthi Thipirineni and actor Nani is presenting this film. Actress Meenakshi Chaudhary is playing the leading lady. Recently, released promotional pictures get a super response from the audience and fans. According to the latest buzz, the makers of this film have released a new poster to announce the trailer release updates of this film. Audiences are eagerly waiting for this update. The film unit is preparing to release this film worldwide on December 2, 2022.

Read: Adivi Shesh Latest News Updates

Pushpa 2: Icon star Allu Arjun’s most prestigious film Pushpa- The Rise under the direction of creative director Sukumar is a super hit. Currently, Bunny and Sukumar are focusing on ‘Pushpa 2.’ As per reports, there will be another key role in Pushpa 2. Heroine Catherine Theresa is also going to act in this film. But it is a negative character in the film. Also another senior police officer character, Manoj Baj Pai is going to act as that character in this film. Anyway, Allu Arjun's acting in 'Pushpa' is within range. Making a character like Pushpraj a star hero is a big risk. But, Bunny handled that risk well. Fans are eagerly waiting for Pushpa 2.

Read: Icon Star Allu Arjun Latest News Updates

Get all the latest news and updates only on HYD7AM. It is one of the best geniue news provider sites which provides every news about Andhra Pradesh and Telangana, like Photo galleries, Fashion news, Bollywood News, Tollywood News, Political news, technical News, Lifestyle News…etc.

For the Latest Tollywood Updates Visit HYD7AM.com

[lyricsolution-com]

Pushpa 2 The Rule: Sreeleela Steals The Spotlight With Her Electrifying Performance In 'Kissik' | Regional News

‘Pushpa 2: The Rule’ is finally in theatres, ending months of wait. The fans can’t be happier and it seems early trends and reviews are all heading for a blockbuster run of the massy actioner. Directed by Sukumar, this Allu Arjun-starrer is highly praised by viewers who went in for the first day first show. The film also stars Rashmika Mandanna, and Fahadh Faasil in pivotal roles.  “Sreeleela set…

[demovibes]

Jolly llb 2 movie free

Jolly LLB 2 video (2017) Akshay Kumar SuperHit Hindi Movie. jolly llb full clip, jolly llb 3GP Mp4 HD Trailer, jolly llb movie, jolly llb mp3, jolly llb download. Real-time popularity on IMDb.īawara Mann Full Video Song Jolly LLB 2 Hindi Movie 2017 Akshay Kumar. 1a1b18d4e8 47 Most Anticipated New Indian Movies and Shows. The video soundtrack was released on 13 January 2017 and it consists of four songs which includes one Qawaali song too. Rizvi, gives Jolly 4 days of time to prove himself. the Chairman of the Discipline Committee, Mr. Jolly LL.B 2, known also as Jolly LL.B 2, is a 2017 Indian Hindi-language black. Jolly LLB 2 | Black-Comedy Hindi video | Akshay Kumar | Huma Qureshi | Annu Kapoor. Jolly llb 2 Movie HD | Jolly llb 2 full hindi movie | Akshay kumar | Hindi movies . Download Jolly Llb 2 Mp4 & 3gp HD, Download Jolly Llb 2 Mp4, Video Mp4. Janu| Rating: 4/5 | Full Review… Meena Iyer  It is the fine display of histrionics by all these refined actors which makes the movie worth seeing. Get the free tool -to freeload Jolly LLB 2 movie HD 720p, MP4 3GP AVI MKV . It's no mean feat if you need Jolly LLB 2 video download 720p in HD. Jolly LLB 2 movie 2017, a sequel to its widely-known 2013 courtroom comedy. It is the fine display of histrionics by all these refined actors, which makes the movie, worth seeing.Jolly LLB 2 4 3gp Movie Download In Hindi Huma and Annu are also compelling enough. In top-form, he puts up a perfect display of a street-smart lawyer who hasn’t read legal tomes but who has instead picked up tips from courtroom corridors to become Jolly LLB. But there are portions that seem contrived.Īkshay changes shades from crooked to straight, like a chameleon. Their weighty arguments do educate and entertain to some degree. The maker tries to pack in too much legal diatribe between Jolly and his adversary, the topnotch, Pramod Mathur(Annu Kapoor), in Judge Tripathy’s (Saurabh Shukla, delightful as always) Lucknow courtroom. Post interval though, the film hits a pause button at times. With cops playing villains and terrorists changing religions, legal greenhorn Jolly finds himself dodging bullets in Kanpur, Lucknow and Manali(doubling up for Kashmir.)Īlso Read : Sayani Gupta's role in 'Jolly LLB 2' revealed! The film also provides the right dose of action inside and outside the courtroom. The plot has enough laugh-out-loud situations and emotional outbursts to keep you invested especially in the razor-sharp first half.

While the last instalment dealt with a hit-n-run case, this one deals with the case of mistaken identity of a J & K terrorist. Writer-director Subhash Kapoor who has studied India’s burgeoning legal system of `I-will-see-you-in-court’, definitely knows as much about the Indian Penal Code as most legal sharks because of his deep study of the subject. But these are just asides and not the main premise of courtroom drama, which in many ways follows the template of the 2013 prequel, Jolly LLB.Īlso Read : ‘Jolly LLB 2’ box-office collection Day 6 At home, he is the hen-pecked husband of lush, Pushpa Panday(Huma) who loves whisky, Gucci dresses and her chubby son in that order. JOLLY LLB 2 REVIEW : On the face of it, apna Jolly is a novice indulging in petty crimes because he knows the loopholes in the law.

[interiorsmmorg]

Baahubali 2 hindi showtimes

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While the performances of the lead cast are all believable, it is Peter Hein’s action-with Baahubali doing the Van Damme split and some sweeps that set your spirits soaring.Īlso Read: ‘Baahubali 2: The Conclusion’ box-office collection Day 5: Film’s Hindi version mints Rs 197. 7.95 crore more and now the film is just Rs. The romance between Devasena and Amarendra has the Titanic fervour. the 18th day in theaters, Baahubali 2 Hindi has approached the Rs. Of course it is CGI and VFX that grab you in your seat, but Baahubali also takes you on an emotional rollercoaster ride. He once again gives us our Benhur and Ten Commandments experience rolled into one. Those two films couldn’t knock The Fate of the Furious off top spot though, as the action blockbuster added another 19.4 million, to take its.

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Indian cinephiles must salute Rajamouli for his vision and ambition. That would be the news of the weekend if it wasn’t for Baahubali 2: The Conclusion earning the best weekend for a Bollywood movie in history with a stellar 10.1 million from just 425 locations. Starring: Prabhas, Rana Daggubati, Anushka Shetty. To avenge his fathers death, a young man leads an army into battle against a cruel tyrant in this Tamil conclusion to the historic saga. What’s more, this part provides an answer to a question uppermost in everyone’s mind for the last two years-it tells you why Katappa, the old faithful, killed Baahubali Senior. Baahubali 2: The Conclusion (Tamil Version) 2017 TV-MA 2h 46m Action & Adventure. Baahubali has been sketched out as such a symbol of strength and power that he makes you root for him throughout. Part 2-The Conclusion onerously carries the equity of the first part on its shoulder and ups the scale on many counts-especially in heroism. It is a visual extravaganza that India must feast on. Of course, the end comes together in a long-drawn climax that could have been 10-minutes shorter.īut don’t judge Baahubali. Even with an earning of 1.40 in its ninth week, Pushpa has surpassed blockbuster films Allu Arjuns Pushpa (Hindi) beats Ajay Devgns Tanhaji, Dangal and Baahubali 2 at box office in 9th week Allu Arjuns Pushpa (Hindi) beats Ajay Devgns Tanhaji. Albeit with some childish conspiracy theories added in. The film completed two months in theaters on February 17, but the earnings are still on.

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It also delves on the love-story between Amarendra and Devasena(Anushka Shetty), who is mother of Mahendra Baahubali(Prabhas in a dual role.) Recounted in the folklore-meets-Aesop’s fable-style, the plot is simple and carries the good triumphs over evil thought forward just like the first part did. BAAHUBALI 2 :THE CONCLUSION FULL MOVIE HINDI (2017)HD 720P-PRABHAS,ANUSHKA SHETTY,RANA DUGGUBATTI. His story is juxtaposed with past events that unfolded in the Mahishmati Kingdom. When Shiva, the son of Bahubali, learns about his heritage, he begins to look for answers. With Prabhas, Rana Daggubati, Anushka Shetty, Sathyaraj. Download and listen to all Baahubali 2- The conclusion movie MP3 songs in high-quality on 2 Review : This part is more prequel than sequel because initially the story traces the origins of Baahubali’s father, who was originally meant to be the King of Mahishmati. Baahubali 2: The Conclusion: Directed by S.S. The songs from Baahubali 2- The conclusion movie are Jiyo Re Bahubali, Jay Jaykara, Soja Zara, Veeron Ka Veer Aa, and Shivam. Go to for updated theater list Collected 19. All the Baahubali 2- The conclusion movie songs are voiced by renowned Bollywood singers namely Daler Mehndi, Sanjeev Chimmalgi, Kailash Kher, Madhushree, Aditi Paul, Kaala Bhairava, and Deepu. There are a total of 5 songs from Baahubali 2- The conclusion movie which are fabulously composed by M. All these songs are from the movie Baahubali 2- The conclusion, a Hindi-language epic action film starring Prabhas, Rana Daggubati, Anushka Shetty, and Tamannaah in the lead roles. These songs are released by Zee Music in April 2017.

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[telugumovienews]

Icon star Allu Arjun gained craze in pan India range with 'Pushpa: The Rise' directed by Sukumar. However, the shooting of the second part 'Pushpa: The Rule' has not started yet, even though this film has been released for almost a year. There are no official updates about the shooting and other aspects of the movie. Bunny fans are deeply disappointed with this. Recently, they also protested.

Meanwhile, there are various news about Pushpa-2. Some say that the shooting has already started silently.. Enough content for the teaser is already ready and Pushpa-2 teaser will be shown in the theaters of 'Avatar-2' which is releasing on December 16. However, no official announcement has been made. For more information visit Teluguone.com official website

[bitacoraclinica]

Caso 1: Deficiencia de Carnitina Palmitoil Transferasa tipo 2 (CPT2) - (New York Times).

El dolor comenzó justo cuando el joven estudiante de enfermería se dirigió por el sendero rocoso en diciembre pasado. De repente, sus muslos y pantorrillas comenzaron a arder y palpitar como si sus músculos estuvieran agotados, como si acabara de correr un maratón. - Dra Lisa Sanders (Síguela en Twitter: https://twitter.com/lisasandersmd)

"Comienza en mis piernas y me sube por la espalda, todo el camino hasta la mandíbula y las mejillas […] Quiero vivir, no dejar que esto arruine mi vida".

Paciente (Px) femenina de 23 años, estudiante de enfermería. Con evolución de 9 años. Respecto a la dieta ella refiere un consumo alto de ácidos grasos, actividad física intensa, llegando a estar en diferentes clubes deportivos, sin embargo durante la preparatorio tuvo que abandonarlos por el incremento del dolor y la frecuencia en que estos aparecían.

Dolor opresivo ascendente.

Orina de color Café a negro (para mas información de los colores de la orina, puedes ingresar en https://www.mayoclinic.org/es-es/diseases-conditions/urine-color/symptoms-causes/syc-20367333).

Incremento de Creatinina quinasa [CK]

CK es un tipo de proteína conocida como enzima. Se encuentra principalmente en los músculos esqueléticos y el corazón, y en cantidades menores en el cerebro. Los músculos esqueléticos son los que están unidos al esqueleto. Funcionan con los huesos para ayudarnos a movernos y le entregan poder y fuerza al cuerpo. El músculo cardíaco (miocardio) bombea sangre hacia y desde el corazón. La prueba de CK se suele usar para diagnosticar y monitorear las lesiones y enfermedades musculares, por ejemplo: 

1. Distrofia muscular: Enfermedad hereditaria poco común que causa debilidad, degeneración del tejido muscular y mal funcionamiento de los músculos esqueléticos. Afecta principalmente a los hombres.

 2. Rabdomiólisis: Destrucción rápida del tejido muscular. Puede ser causada por una lesión grave o una enfermedad muscular o de otro tipo

Único antecedente familiar, la madre muestra dolores opresivos en las piernas.

Los episodios de dolores suelen darse al hacer ejercicio o caminar.

Antecedentes: Ella inicia los dolores a la edad e 14 años, sin explicación aparente, llegando ir al hospital 4 veces por año, en la misma fecha. Con el paso del tiempo el dolor fue intensificando y ampliándose, llegando hasta las mejillas, siempre iniciando en las piernas. El padre sospecha de alguna enfermedad hereditaria, relacionándolo con los dolores que presenta la madre.

Al principio se sospecha para posible diagnostico (Dx):

Artritis reumatoide

Lupus

Estreptococosis

Enfermedad de la tiroides

Para las cuales da negativo.

Repercusión económica de la Px: Ha sido demanda varias ocasiones por doctores y hospitales, ella suele ser internada y su alta solo es concedida cuando sus niveles de CK normalicen. Ha tenido que declararse en bancarrota en diferentes ocasiones.

Entra al siguiente enlace: Clínica del Px en el 2012: https://int.nyt.com/data/ugc/diagnosis/angel-med-records-2012.pdf

Entra al siguiente enlace: Clínica del Px en el 2017: https://int.nyt.com/data/ugc/diagnosis/angel-med-records-2017.pdf

Solicita la ayuda de la Dra Lisa Sanders, médica estadounidense, autora médica y periodista,  profesora asociada de medicina interna y educación en la Facultad de Medicina de Yale. En 2002, comenzó a escribir una columna para The New York Times llamada Diagnóstico, que cubría casos de misterio médico. Ella es médica tratante en el Hospital Yale-New Haven, fue consultora médica para la serie House MD. En la publicación del caso en New York Times, recibe varias sugerencias de posibles Dx entre los cuales destacaron:

Trastornos de almacenamiento de la glucosa

Trastornos de la oxidación de ácidos grasos

Enfermedad de Pompe

Enfermedad de Lyme

Enfermedad de McArdle

Deficiencia de carnitina palmitoil transferasa tipo 2

Problemas mitocondriales

Considerado por la Dra se manejan las miopatías musculares, pero la Px decide enfocarse en la Enfermedad de McArdle solamente, para la cual da negativo.

Tiempo después es contactada de Italia, donde le ofrecen a la Px un estudio gratuito de examen genético sanguíneo para dar con la patología, debido a que atendieron un caso de una niña con la misma sintomatología. Tras el primer examen se descarta un aproximado de 100 enfermedades hereditarias, por lo cual se procede a  realizarle un examen para decodificar su genoma y encontra el daño, tras unos meses se llega a un Dx concluyente, Deficiencia de Carnitina Palmitoil Transferasa tipo 2. Se procede a la modificación de la dieta de la Px.

Actualidad: La Px modificó los hábitos alimenticios, los episodios de dolor continúan, pero son tolerables. Se ha graduado de enfermería y ejerce de tiempo completo.

¿Te interesa leer el caso? Entra al siguiente link

https://www.nytimes.com/interactive/2018/04/11/magazine/netflix-diagnosis-series-angels-severe-muscle-pain.html

ANÁLISIS DE LA PATOLOGÍA

El déficit de Carnitina Palmitoiltranferasa II (CPT II o CPT 2) es una enfermedad metabólica hereditaria que afecta a la oxidación mitocondrial de los ácidos grasos de cadena larga (LCFA). Se conocen tres formas del déficit de CPT II: forma miopática, forma infantil grave y forma neonatal.

Los ácidos grasos proporcionan la energía de reserva que se utilizara cuando el individuo se queda sin la principal fuente energética, la glucosa. Cunado hay un déficit de la enzima, el cuerpo no metaboliza las gradas provocando sea utilizada solamente la glucosa la cual no es suficiente.

La deficiencia de las CPT-2 en adultos, suele aparecer entre los 13-15 años de edad con la descomposición de las fibras musculares al realizar actividad física, presentando comúnmente los siguientes síntomas:

dolores musculares

debilidad muscular

calambres

orina de color marrón rojiza

en algunos casos, si no se trata puede generar insuficiencia renal.

La concentración sérica de CK es más de cinco veces la normal cuando se excluye la enfermedad cardíaca o cerebral

La mayoría de las personas con la forma miopática de deficiencia de CPT2 tienen una concentración normal de CK en suero (<80 U / L) entre los ataques. Se observa una elevación permanente de la concentración sérica de CK (≤313 U / L) en aproximadamente el 10% de los individuos afectados.

Respecto al diagnostico este se basa inicialmente en la espectrometría de masas en tándem de las acilcarnitinas plasmáticas, seguido de un test genético y de la medida de la actividad enzimática de CPT2 en los linfocitos circulantes, músculo o fibroblastos en cultivo, sin embargo es recomendable el diagnostico diferencial para la enfermedad de McArdle, la distrofia muscular de Duchenne, y el déficit en citocromo C oxidasa entre otros; y el déficit de carnitina-acilcarnitina translocasa (CACT) y el déficit de acil-CoA deshidrogenasa de cadena muy larga (LCAD) para las formas infantiles y neonatales. Es sugerido un mapeo genético para identificar la transmisión recesiva.

El tratamiento suele constar de varios puntos:

Evitar ayunos prolongados.

Aumento el consumo de alimentos ricos en glucosa y disminución del consumo de ácidos grasos.

El aceite de triglicérido de cadena media (MCT) se utiliza a veces como parte del plan alimenticio.

Evitar ejercicio intenso y frió.

Puede suministrar al paciente L-carnitina

Bibliografía recomendada:

Pushpa Raj Joshi & Stephan Zierz. (2020). Muscle Carnitine Palmitoyltransferase II (CPT II) Deficiency: A Conceptual Approach. Molecules

Diana Lehmann, Leila Motlagh, Dina Robaa & Stephan Zierz. (2017). Muscle Carnitine Palmitoyltransferase II Deficiency: A Review of Enzymatic Controversy and Clinical Features. International Journal of Molecular Sciences.

Eva Márquez Liétor, Rosa Pello Gutiérrez, Sara Jiménez Garcia,Vanesa Castañón Bernardo, Joaquín Arenas Barbero & Miguel A. Martín Casanueva. (2008). Identificación de mutaciones en el gen CPT2en un caso con déficit muscular de carnitina palmitoiltransferasa II. Revista del Laboratorio Clínico.

Ponton, Raul Alberto. (2005). Enfermedades relacionadas con la nutrición: déficit de carnitina. INVENIO.

Wieser, Thomas (2004). Deficiencia de carnitina palmitoiltransferasa II. GeneReviews.

Martínez Pardo, Mercedes; Gómez López, Lilian; Ruiz Pons, Mónica; Sánchez-Valverde Visus, Félix & Dalmau Serra, Jaime. (SF). Diagnóstico y tratamiento de las alteraciones de la oxidación mitocondrial de las grasas. Protocolos diagnóstico-terapéuticos de Gastroenterología, Hepatología y Nutrición Pediátrica.

[ijtsrd]

Prevalence of Gene Polymorphisms in Intervertebral Disc Degenerative Diseases

BY Mr. C. Marimuthu | Dr. V. Pushpa Rani | Dr. V. Judia Harriet Sumathy "Prevalence of Gene Polymorphisms in Intervertebral Disc Degenerative Diseases"

Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-2 , February 2019,

URL: https://www.ijtsrd.com/papers/ijtsrd19153.pdf

Paper URL: https://www.ijtsrd.com/biological-science/molecular-biology/19153/prevalence-of-gene-polymorphisms-in-intervertebral-disc-degenerative-diseases/mr-c-marimuthu

call for paper social science, ugc approved journals for social science, social science journal

Intervertebral disc diseases is otherwise known as breakdown of one or more discs that separate the bone of the spine, Which cause pain in the back, neck as well as frequent pain in legs and arms. The general role of intervertebral discs is to provide the cushioning between vertebrae and absorb the pressure that is exerted on the spine. Generally low back pain LBP is considered as common disorder from disc degenerative diseases. The main reason of the LBP is due to contribution of intervertebral disc diseases and combination of genetic and environmental factors. Most of these factor identified , But some of these remain unidentified. However recent researches identified that variations in several genes may influence the risc of intervertebral disc diseases . Most of the variations associated with genes related with immune function leads to increase risk of intervertebral disc diseases . Most of these genes plays a vital role in immune response like inflammation and water loss dehydration of the discs, Which causes their degeneration. This review focuses on the evidence of genetic disposition, the genes or biological processes that are implicated, and the need to consolidate resources and clarify phenotype definition to take advantage of the new technologies in genetic analysis to enhance our understanding of this condition.