#New areas

[reasonsforhope]

A new treatment combining ReCET and semaglutide could eliminate the need for insulin in type 2 diabetes, with 86% of participants in a study no longer requiring insulin therapy. The treatment was safe and well-tolerated, and further trials are planned to confirm these results.

Groundbreaking research presented at UEG Week 2024 introduces a promising new treatment approach for type 2 diabetes (T2D) that has the potential to greatly reduce or even eliminate the need for insulin therapy.

This innovative approach, which combines a novel procedure known as ReCET (Re-Cellularization via Electroporation Therapy) with semaglutide, resulted in the elimination of insulin therapy for 86% of patients.

Globally, T2D affects 422 million people... While insulin therapy is commonly used to manage blood sugar levels in T2D patients, it can result in side effects... and further complicate diabetes management. [Note: Also very importantly it's fucking bankrupting people who need it!!] A need therefore exists for alternative treatment strategies.

Study Design and Outcomes

The first-in-human study included 14 participants aged 28 to 75 years, with body mass indices ranging from 24 to 40 kg/m². Each participant underwent the ReCET procedure under deep sedation, a treatment intended to improve the body’s sensitivity to its own insulin. Following the procedure, participants adhered to a two-week isocaloric liquid diet, after which semaglutide was gradually titrated up to 1mg/week.

Remarkably, at the 6- and 12-month follow-up, 86% of participants (12 out of 14) no longer required insulin therapy, and this success continued through the 24-month follow-up. In these cases, all patients maintained glycaemic control, with HbA1c levels remaining below 7.5%.

Tolerability and Safety

The maximum dose of semaglutide was well-tolerated by 93% of participants, one individual could not increase to the maximum dose due to nausea. All patients successfully completed the ReCET procedure, and no serious adverse effects were reported.

Dr Celine Busch, lead author of the study, commented, “These findings are very encouraging, suggesting that ReCET is a safe and feasible procedure that, when combined with semaglutide, can effectively eliminate the need for insulin therapy.”

“Unlike drug therapy, which requires daily medication adherence, ReCET is compliance-free [meaning: you don't have to take it every day], addressing the critical issue of ongoing patient adherence in the management of T2D. In addition, the treatment is disease-modifying: it improves the patient’s sensitivity to their own (endogenous) insulin, tackling the root cause of the disease, as opposed to currently available drug therapies, that are at best disease-controlling.”

Looking ahead, the researchers plan to conduct larger randomized controlled trials to further validate these findings. Dr. Busch added, “We are currently conducting the EMINENT-2 trial with the same inclusion and exclusion criteria and administration of semaglutide, but with either a sham procedure or ReCET. This study will also include mechanistic assessments to evaluate the underlying mechanism of ReCET.”

-via SciTechDaily, October 17, 2024

--

Note: If it works even half as well as suggested, this could free so many people from the burden of the ongoing ridiculous cost of insulin. Pharma companies that make insulin can go choke (hopefully).

[spicybeefu]

What if Pokemon & Animal crossing had a crossover game?! #4 Made in Blender, design originally by lemoncreamsicle

[disabilityhorizons]

Now available on Disability Horizons Shop!

[heart-of-the-morningstar]

✨Sensitivity✨

I am an absolute SLUT for Luci’s wings so I wanted to write something with them :), huge thank you to @myhornybrainonlyknowsthis for the help 💖

Also I’m legit on a cruise ship rn, but @amberlouise473 knows I gotta feed y’all like I’m tossing corn to my chickens 🤣

Lucifer x f!sinner reader

Summary: You’re super curious about Lucifer’s wings, but neither of you knew how sensitive they were. You didn’t know how sensitive you could be either…

Warnings: 18+, smut, dry humping, ruined clothes, pet names, oral (f receiving), face riding, over stimulation, multiple orgasms

It was time for bed and Lucifer was still working. You knew he worked late sometimes but this seemed a little later than usual. You decided to take a look to see if he was still in his office. Sure enough, you saw him sitting down at his desk when you entered the room. But when you looked closer, you saw that he’d fallen asleep at his desk, his head resting in his arms. He looked so peaceful lying there, you almost didn’t want to disturb him. But you knew he’d feel a lot better if he actually slept in your bed instead of hunched over his desk. Quietly, you walked towards him trying not to make any loud noises that might startle him. You placed a hand on his shoulder, shaking it lightly.

“Luci?,” you whispered, “Luci, it’s time for bed, wake up sleepy head.” He moaned quietly, but your shaking didn’t seem to have done the trick. You shook his shoulder a little hard. “Luci, c’mon hon.” Nothing. You took your other hand and placed it on his other shoulder, shaking him even more. “Lucifer!,” you nearly screamed!

With that, Lucifer’s eyes shot open, pushing himself off the desk. “AAHHH!!! WHAT?!?! What’s going on?!,” he yelled. You never saw him so frazzled before, it was kind of cute. But what you really didn’t expect was to see Lucifer’s wings spring out from his back. It must have been an involuntary reaction from the shock of being woken up so suddenly. His eyes found yours and he breathed a sigh of relief.

“Oh, it’s you, darling,” he breathed. “You really scared me there! I guess I must have fallen asleep, forgive me.” You were only half listening to him at this moment, your gaze was still fixed on his angelic wings. You’d only seen them once or twice before, but never for long. It was then that Lucifer turned his head and noticed what had caught your attention. “Oh! Sorry about that, it’s a defense mechanism, as silly as that sounds. I’ll put them away-”

“No, wait!”, you shouted louder than you meant to. Lucifer cocked an eyebrow at you, not understanding why you had stopped him. “Sorry, I didn’t mean to yell. It’s just…I never get to see your wings. They’re really beautiful.”

A light blush dashed across his face, he gave you a shy smile. “O-oh, thank you! I don’t think anyone’s ever said that to me.”

“That’s a shame,” you pouted, “I think they’re incredible.” You walked closer to him to get a better look at them. Their white and red coloring were breathtaking. Their length took up almost the entirety of the room you were in, and his office was not small in the least. A tiny part of you wondered if he always had red feathers, or if they had changed after he…

Perhaps that was a question for another time.

“Are they heavy?,” you inquired.

“Oh! Umm, I don’t think so,” Lucifer pondered. “I don’t really notice if they are. I might have gotten used to them over the last 10,000 or so years.”

“Can I…touch them?,” you asked shyly, averting Lucifer’s gaze.

He smiled. “Of course, love. Let’s go back to our room, shall we?”

Lucifer’s wings disappeared for now as he gently grabbed your hand and led you out of his office. Once you reached your bedroom, he unfastened his shirt and threw it off to the side. It made you blush, even though his bare chest was not a new sight to you. Lucifer noticed your reddened face and smirked.

“It’s a little easier this way, don’t you think?,” he chuckled. He walked over to the bed and sat down, crossing his legs in the process. He tapped his thigh, offering you a seat in his lap. You smiled and wrapped your legs around his torso, straddling him. “You ready?,” he asked with a little smile. You nodded your head eagerly. In an instant, his three sets wings appeared again. You noticed something was a little different though.

“I could have sworn they were bigger,” you puzzled.

“No, you’re right, they were,” Lucifer laughed. “I can control how large or small they need to be. They might have broken something in here if they were any bigger!”

You chuckled lightly. They were even more breathtaking up close, his scarlet feathers glistened even in the dim lighting of the room. You stuck out your hands and touched the top of his first set of wings. Unexpectedly, Lucifer inhaled sharply from your touch, screwing his eyes shut. You pulled away instantly.

“Oh no!,” you gasped. “Did I hurt you? I swear I barely touched them! I’m sorry!”

Lucifer exhaled slowly and opened his eyes again. “No, no, it’s alright, love,” he cooed, “it wasn’t painful. I just didn’t expect the sensation. Let’s just say they’re…more sensitive than I originally thought.” It was only then you felt a bump forming between your legs.

Oh…OH!

You quickly caught on to what he was referring to. And having you straddle his lap probably wasn’t helping. A small smirk crept across your face. You couldn’t resist the urge to make him squirm from your touch; the thought excited you.

“Well, in that case…” you smiled slyly, reaching out for his wings once more. This time, you gave them a slightly firmer grip than before. Lucifer nearly yelped from your touch and buried his face into the crook of your neck. You ran your hands up and down the tops of his wings, almost massaging them in a way. Lucifer was unable to hold back his moans.

“You’re gonna be the death of me, sweetheart,” he panted.

You loved the sight of him bending so easily to your simple touches. You wondered if you could break him. You began to shift your hips in his lap, grinding on the now very apparent bulge in his pants. Lucifer nearly sobbed as you ground your hips against him. You moved your hands down to his second set of wings to give them some attention. You could tell he was unraveling quickly.

“D-Dear,” he choked out, “i-if you don’t stop, I’m g-gonna…f-fuck…”

His plea only made you grind against him at a faster pace while continuing to stroke his sensitive wings. At this point he couldn’t even form a coherent sentence, only broken moans and gutural sounds left his lips. You moved your hands down to his smallest set of his wings, pinching them between your fingers.

“FuckfuckfuckFUCK,” Lucifer cried out as your movements finally pushed him over the edge. He bit down on your shoulder as he came, completely ruining in pants. Once he came down from his high, he looked into your eyes, almost distraught.

“I’m…I’m so sorry,” he whimpered. “I-I didn’t think that…I didn’t mean to…” He couldn’t finish his sentence. His wings disappeared from sight as he buried his head into you chest

“Hey, hey, it’s alright,” you told him as you lifted his head up to plant a tender kiss to his lips. The small tears that had formed in his eyes fell down the side of his face, but you wiped them away with your thumbs. “Luci, please don’t apologize,” you soothed. “You never have to feel sorry for that! Did you feel good?”

Lucifer steadied his breathing, trying his best to calm down. “Yes, love, it was amazing. You’re amazing.” He lifted you off his lap and placed you on the mattress while he stood up, discarding the rest of his now filthy clothes. “But I absolutely refuse to be the only one being pleasured tonight.”

Without warning, Lucifer leaned down and crashed his lips into yours, filing your mouth with his tongue. You moaned against his lips, feeling as though you might be devoured by him. Lucifer tugged at the hem of your pajama pants, asking permission to remove them. “Mhmm,” was all you could mumble. In one swift motion, your pants had vanished and all you felt was the cool air on your legs. Lucifer brought down his fingers to your folds, loving the feeling of how wet you were for him. He captured your moan on his lips, but suddenly pulled his fingers away, leaving you to whine in protest.

Lucifer broke your kiss and brought his soaked finger to his lips, tasting your sweet nectar. “Mmm, you always taste so delectable, darling,” he marveled. You couldn’t help but blush at his words, he knew just what buttons to press when it came to you. He crawled back up on the bed and laid flat on his back, his head propped up by the pillows. “Come have a seat, sweetheart,” he teased as he pointed to his coy smiling face.

Your face became extreme hot as you crawled towards the demon king. You made your way on top of him and came to a halt when your dripping cunt hovered right above Lucifer’s eager smile.

“A meal fit for a king, truly,” he laughed as he dug his face into your aching pussy. You nearly screamed as his forked tongue worked his magic along your slit. He devoured you, making sure every inch of you was consumed. His lips found your clit and started to kiss and suck at it. He’d only just started and you were ready to snap.

“O-Oh my God, Lucifer, shhhiiittt, I’m so close…s-s-so close…,” you whined.

“God can’t hear you down here, angel,” he teased you before continuing to lap at your folds. He made quick work of you, the knot in your stomach threatening to snap at any moment.

“Fuuuuccckkkk, imcummingIMCUMMIMG,” you screamed as you finally felt your walls clench and spasm around nothing. Lucifer happily swallowed your juices as your orgasm started to recede. You tried to lift yourself up off Lucifer’s face, but he kept a firm grip on your legs.

“I’m not done with you, love,” he chuckled. With a snap of his fingers, golden shackles formed around your ankles, the chain hooked underneath Lucifer’s back. A twisted look of fear and passion flashed across your face. You were trapped.

“L-Luci…what are you-” you tried to asked but were cut off by another long lick up your sensitive cunt. A gutural moan escaped your mouth, you still hadn’t fully recovered from your orgasm.

“I thought it would only be fair to ruin you, since you ruined my clothes,” he chastised playfully. “But if at any time it becomes too much for you, tell me and I’ll let you go immediately, okay?”

“Al-Alright,” you stuttered, trembling from the anticipation.

Lucifer hummed against your lower lips. “I’ll make this a little easier for you, sweetheart.” You saw Lucifer’s form start to change beneath you. His horns had erupted from his head while his eyes shifted to a deep red and gold color with onyx irises. “Something for you to hold onto,” he murmured sensually.

Tentatively, you took hold of his horns and braced yourself for his next move. You didn’t have to wait long before you felt his tongue attacking your cunt once more. The grip you had on his horns could have torn your skin clean off with how tight you were holding them while he nipped and sucked your overstimulated clit. Before you knew it, your second orgasm hit you even harder than the first. Then your third, your fourth, your cunt was getting absolutely abused by Lucifer who hadn’t shown any signs of slowing down since he started. After your fifth orgasm washed over you, your legs had given out from under you, completely collapsing on top of Lucifer.

“No more…,” you begged. “No more, please…”

Lucifer snapped his fingers and the shackles around your ankles disappeared in an instant. You conjured up the remainder of your strength to push yourself off him and roll over onto your side, an absolutely breathless mess. You could hardly keep your eyes open. You could feel yourself losing consciousness until Lucifer pulled you flush to his chest.

“You did so well, my dear,” he murmured against your ear. “Are you alright? Do you need anything?”

“Sleep…” was all you could muster. Lucifer chuckled lightly, kissing your cheek ever so softly.

“Goodnight, love,” you heard him whisper as he wrapped his arms around you and pulled you close. It was the best sleep you ever had.

~~~~

“I just think they’re neat!” - Me w/ Lucifer’s wings also Lucifer inventend pussy eating, this is fact, ALSO also something something handlebar horns

[batcavescolony]

It's not over, till it's over.

[redbelles]

not to whine on main but i am once again b e g g i n g the average tumblr user to stop being so flippantly fucking rude on gifsets. "i don't know why you didn't include this scene—" "ugh i can't stand this character" "actually op this other show is better" "i hate this ship" okay, great. fine. if you have such negative opinions about what i've made, why, pray fucking tell, are you reblogging it? why don't you just reblog sets you actually enjoy? or better yet, make your own. either way: fucking please stop clowning on my mine. it costs zero dollars to keep your garbage to yourself and yet i get so many stupid rude comments every day. i am so tired.

[rapidhighway]

moar

[kensatou]

he's like if a baby cow wandered into a zoom interview

[cayliecoltrane]

quick lil ETHOwO redraw

[sunshinepixels]

Move in day 🚚🏠📦

ft. another florida house from yours truly

[mayor-brandy]

A nice little recycling area (inspired by insta/youtuber boiscrossing) 🌲

[reasonsforhope]

"Over 10,000 square miles of additional protected area will be added to the Heard and McDonald Islands in Australia’s far southern territorial waters.

Coupled with other expansions of existing marine sanctuaries, it puts Australia on course to have 52% of its ocean territory protected, more than any other nation, by the end of the current administration’s term.

“This is not just a huge environmental win for Australia, it’s a huge environmental win for the world,” said Australian Environment Minister Tanya Plibersek. “This is a unique and extraordinary part of our planet. We are doing everything we can to protect it.”

Located over 2,000 miles south of the Australian continent, Heard and McDonald Islands make up about 144 square miles of volcanic terrain that represent one of the most remote places on Earth.

They are important breeding grounds for 19 species of bird, including 4 species of penguins, but dozens of other bird species take refuge there. It is a UNESCO Natural Heritage Site, and a RAMSAR Wetland in addition to being an Australian national marine sanctuary.

The quadrupling of the sanctuary borders amounts to 11.5 thousand square miles, (30,000 sq km) of additional protection, but represents one-tenth of the total proposed expansions of marine protected areas.

Under the current guidance, prepared by nationally sanctioned scientific surveys, the total marine protected areas will make up an area the size of Italy.

The current administration of Prime Minister Anthony Albanese is seeking to establish a new environmental protection agency, as well as set a high bar for the country’s commitments to an international philosophy of conservation governance known shorthand as “30×30” or “30 by 30,” which states that to prevent the worst effects of general environmental degradation worldwide, 30% of land and waters should be under protections. Often the second thirty refers to a hypothetical 2030 deadline."

-via Good News Network, October 10, 2024

[linkedin-offficial]

been busy in the skies!

[grimae]

We come carry the face of a dead sun.

[nukacourier]

Okay so I've gotten a couple of comments here and there whenever I complain about the anti-native american sentiment (aka racism) that's baked into Honest Hearts asking "how is it racist??", which I know it's not my job as a native american fallout fan to teach ignorant white people how something is harmful but I'm gonna spell it out anyways because it's annoying when people constantly act blind to it

First of all, the dlc is very heavy handed with the "uncivilized savage" depiction of native americans. The fact that they had to be TAUGHT how to use guns and use their own natural resources to make medicine are already two examples of this right out of the gate

Plus, the fact all the tribe members wear rudimentary hides, hardly speak english, and sleep on the ground without any buildings (where Joshua and Daniel get to wear normal clothes and Joshua has his own work station) are more examples of this troupe (and its especially stupid since iirc a lot of southwestern tribes were known for making buildings that still exist to this day)

This also ties into the white savior troupe, since as said, the Dead Horses and the Sorrows both had to be taught to take care of themselves and have to be protected by another tribe by two white men (Joshua and Daniel), and that they practically worship them for it because they apparently would've died off if these two white guys didn't intervene

This, plus the fact they're both missionaries who are trying to convert the tribes into a Mormonism is downright offensive as Christianity as a whole has been used as a tool to justify committing genocide against us for centuries. Do I even need to explain this?

And speaking of them needing protection, the White Legs themselves are a whole shitty can of worms, falling right into the (what should be) long-dead idea that if we're not stupid mud people, that natives are bloodthirsty, cannibalistic, warring savages (which. Again. Another tool of propaganda used to literally kill us for as long as white people have been here). Which in turn loops back around to the whole white savior thing with the problem of the White Legs only being solved because Joshua uses his mighty hand of God to take them out or whatever. No matter if you try to end the dlc peacefully you STILL have to do that! It's fucked up!

This post is already lengthy and there's a lot of things I haven't covered (such as the native characters in the dlc generally falling into the "noble indian" troupe), but these are the most glaring issues I can come up with from the top of my head

Tl;dr - quit heralding Honest Hearts as the pinnacle of good writing when it's all built off racism. Listen to us native fans for once, please

[charlietheepicwriter7]

"Probably because they don't have a grave," Danny said, pulling out his vape. "Final resting places are--HEY!"

Nightwing held the pilfered vape above his head. "Where did you get this?" he asked, scandalized.

Danny jumped for it, but Nightwing was too tall! Even at 5'7 he'd have to use his powers to reach the vape; he had no chance as a 9 year old. "We're in Gotham! You're lucky I didn't get cocaine instead!"