#Metabolic syndrome

[ketoandme]

Amazon link to Brain Energy, Dr. Christopher Palmer (2022):

The new scientific research into ketogenic diets or very low carb diets for mental health conditions is turning out to be one of the surprise advances in psychiatry of the past decade. Dr. Chris Palmer is at the forefront; this book summarizes the basics in non-jargonized language accessible to pretty much anyone.

[falseandrealultravival]

The house that gives birth to metabolic syndrome (verse)

metabolic syndrome

in a TV commercial

I saw the PanaHome broadcast

In the explanation, the line of flow (the path that moves in the work)

People who do housework because they are organized

It is said that the distance to move is reduced

About 140km per year.

I see, this is easy!

However - as long as it doesn't move

The body's calorie-burning function does not work

It is stored in the body as excess energy.

This is not about metabolic syndrome!

It is a house that gives birth to metabolic syndrome.

Note :”PanaHome” is a housing maker in Japan.

(2018.04.20)

メタボを産む家

テレビコマーシャルで

パナホームの放送を見た

何でも動線（作業で動く経路）を

整理したので家事をやる人は

年間１４０ｋｍくらいは

動く距離が減るのだという。

なるほど、これは楽！

ただし――動かない分は

体のカロリー消費機能は働かず

過剰エネルギーとして体に蓄積される。

これってメタボのことじゃん！

メタボを産む家である。

[drritamarie]

Blood Sugar Balancing Vegan Ice Cream Cake

Indulge in this delightful and guilt-free treat. Vegan Ice Cream Cake is a delectable dessert designed to support stable blood glucose levels and promote overall well-being.

What is Blood Sugar Balancing Non-Dairy Vegan Ice Cream Cake Made Of?

Blood Sugar Balancing Vegan Ice Cream Cake tastes incredible and is packed with nourishing ingredients. 

The crust blends the flavor of nuts and seeds, complemented by a touch of Luo Han for added sweetness.

The ice cream base is crafted with frozen zucchini, coconut butter, nuts, raw chocolate (cacao), essential oils, and superfoods. 

This vegan ice cream combines mint and chocolate that tastes like a decadent treat.  It is dairy-free, gluten free, sugar-free and hormone balancing.

[fasting4weightloss]

[medifact]

Metabolic syndrome is actually a cluster of medical conditions such as abdominal obesity, high blood pressure, high blood sugar and high cholesterol, which are associated with higher risk of developing cardiovascular disease and type 2 diabetes. 

[sehat86]

How metabolic syndrome affects Parkinson’s Disease - Easy Health Options®

[bitspieces]

Ahah yeah they were so stupid.

Until you realise he referred to fava beans, not regular beans, that can trigger glucose-6-phosphate dehydrogenase deficiency, which in italian is still called favismo for this reason. And it's the most common enzyme deficiency world wide, it causes very bad anemia and is particularly common in southern Italy and the Mediterranean region (possibly because it gives some degree of protection against malaria), where fava beans were coincidentally a staple food source.

So yeah ancient people did believe whatever but their weird beliefs often stemmed from very practical empirical observations. The explanations might have been bizzarre but the concern was well placed.

Source:

https://en.m.wikipedia.org/wiki/Glucose-6-phosphate_dehydrogenase_deficiency

life back then mustv been crazy people just thought whatever

[blueoaknx]

The Role of Mitochondria in Menopause

Introduction

Menopause signifies a pivotal transition in a woman's life, characterized by the cessation of ovarian function and a marked decline in estrogen levels. This phase is associated with various physiological changes and an increased risk of several health conditions, including metabolic syndrome, osteoporosis, and cardiovascular diseases. Recent studies have illuminated the significant role of mitochondria—the organelles often referred to as the "powerhouses of the cell"—in the physiological processes that accompany menopause. This article seeks to elucidate the multifaceted roles of mitochondria in menopause, highlighting their involvement in energy metabolism, hormonal regulation, oxidative stress management, and overall cellular health.

Mitochondrial Structure and Function

Mitochondria are double-membraned organelles that possess their own circular DNA (mtDNA), a remnant of their evolutionary origin from ancestral prokaryotic cells. These organelles are essential for several critical functions, including:

Adenosine Triphosphate (ATP) Production: Mitochondria generate ATP via oxidative phosphorylation (OXPHOS), facilitated by the electron transport chain (ETC) embedded in the inner mitochondrial membrane.

Metabolic Pathways: Mitochondria are central to various metabolic pathways, including the tricarboxylic acid (TCA) cycle, fatty acid oxidation, and the urea cycle, integrating cellular energy production and metabolism.

Regulation of Apoptosis: Mitochondria play a crucial role in apoptosis by releasing pro-apoptotic factors such as cytochrome c, thereby initiating programmed cell death essential for cellular homeostasis.

Mitochondrial Dysfunction in Menopause

The decline in estrogen during menopause is closely linked to changes in mitochondrial function:

Mitochondrial Biogenesis: Estrogen is known to stimulate mitochondrial biogenesis through the activation of peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α). The reduction in estrogen levels during menopause leads to diminished PGC-1α activity, resulting in decreased mitochondrial density and compromised function.

Oxidative Stress: Mitochondrial respiration generates reactive oxygen species (ROS) as byproducts. In the context of menopause, reduced estrogen levels can impair the body's antioxidant defenses, leading to an increase in oxidative stress. Elevated ROS can cause damage to mitochondrial DNA, proteins, and lipids, resulting in further mitochondrial dysfunction.

Altered Energy Metabolism: The menopausal transition is frequently associated with metabolic syndrome, characterized by increased fat accumulation and insulin resistance. Mitochondrial dysfunction is a contributing factor to impaired fatty acid oxidation and energy dysregulation, resulting in increased visceral fat deposition.

Hormonal Regulation and Mitochondrial Function

Mitochondria are integral to the synthesis of steroid hormones, including estrogen. While the ovaries serve as the primary site for estrogen production, peripheral tissues, such as adipose tissue, can synthesize estrogen from androgens via the aromatization process. Adequate mitochondrial function is crucial for this synthesis. Consequently, mitochondrial dysfunction may exacerbate symptoms associated with estrogen deficiency.

Moreover, mitochondrial involvement in cortisol metabolism may also be significant. Cortisol, produced by the adrenal glands, influences energy metabolism and stress response. Dysregulation in cortisol metabolism due to mitochondrial dysfunction can lead to increased fatigue and mood disturbances commonly observed during menopause.

Inflammation and Mitochondrial Dysfunction

Mitochondrial dysfunction is closely linked to chronic inflammation, frequently observed in menopausal women. As mitochondrial function declines, the production of pro-inflammatory cytokines increases, contributing to systemic inflammation. This chronic inflammatory state may exacerbate various menopausal symptoms, including joint pain, mood disorders, and cardiovascular risks.

Mitochondria also play a role in inflammasome activation, a multi-protein complex critical to the immune response. Dysregulation of this pathway in the context of mitochondrial dysfunction can lead to excessive inflammation, further complicating health during menopause.

Interventions to Support Mitochondrial Health

Given the integral role of mitochondria in menopause, various interventions may be employed to support mitochondrial function:

Physical Activity: Regular exercise has been shown to enhance mitochondrial biogenesis and improve oxidative phosphorylation. Exercise stimulates the expression of PGC-1α, promoting mitochondrial health and improving metabolic outcomes.

Nutritional Interventions: Diets rich in antioxidants (e.g., vitamins C and E, polyphenols) can help mitigate oxidative stress. Omega-3 fatty acids, found in fish oil, support mitochondrial function by reducing inflammation.

Caloric Restriction and Intermittent Fasting: These practices enhance mitochondrial efficiency and promote autophagy, a process that eliminates damaged mitochondria and supports cellular health.

Supplementation: Certain supplements, such as Coenzyme Q10, alpha-lipoic acid, and L-carnitine, may directly support mitochondrial function and reduce oxidative stress.

Hormone Replacement Therapy (HRT): For some women, HRT may alleviate menopausal symptoms and support mitochondrial function by restoring estrogen levels; however, this approach requires careful consideration of individual risks and benefits.

Conclusion

Mitochondria are critical contributors to the physiological changes associated with menopause, influencing energy metabolism, hormonal balance, oxidative stress, and inflammation. A comprehensive understanding of the intricate relationship between mitochondrial function and menopausal symptoms can inform targeted interventions to support women's health during this transition. By prioritizing mitochondrial health through lifestyle modifications and potential therapeutic strategies, women may enhance their quality of life and mitigate health risks associated with menopause. Continued research is essential to explore the complex interplay between mitochondrial dynamics and menopausal physiology, paving the way for novel therapeutic approaches and interventions.

[smarteatinghabits]

Aspartame: A Sweet Debate - Weighing the Pros and Cons

Aspartame: Friend or Foe? 🥤🍬 Explore the sweet debate on this low-calorie sweetener. Is it safe or should we steer clear? Discover the surprising truth in our latest article. #aspartame #health #sweetener #diet #nutrition #food #science #healthtips #fit

Aspartame, a food additive, a low-calorie sweetener commonly found in diet sodas, chewing gum, and other products, has been a topic of much debate over the years. While it’s often touted as a healthier alternative to sugar, concerns about its potential health risks have persisted. In this comprehensive article, we’ll delve into the world of aspartame, exploring both its positive and negative…

[ketoandme]

Gary Taubes came to prominence back in 2000 with a pathbreaking article in the New York Times Magazine reviewing the evidence about obesity and weight loss that challenged the still-prevailing-today wisdom. It was widely reviled and rejected in the medical and public health expert communities - by everyone, pretty much, except for those who had been utterly desperate to lose weight and keep it off.

I was one of those people who - well, I guess I'd say, in the context of this Tumblr blog and the zillions of girls here who have embraced precisely the mindset they have been taught by health and wellness classes, doctors, etc. - the belief that gaining or losing weight is simply calories eaten versus calories burned. And taught and internalized that your inability to lose weight, yours and mine both, was due to lack of willpower and self discipline. Eat less, move more … exhortations proffered by the experts to the masses even as obesity, type 2 diabetes, all the conditions now called metabolic syndrome, exploded in the population.

That article and Taubes' later books offered an alternative and scientifically persuasive, imao, shift in understanding the science of weight gain and loss, for me and increasingly for millions of failed dieters who ditched calories in / calories out model of obesity - understanding that the human body is not a “bomb calorimeter,” burning food to ash to determine heat generated. What the body does with food depends in the first place on the type of macronutrient - carbs, fats, and protein - and the mind boggling complex metabolic biochemistry that governs how they are processed, used, and stored. The most important part of that story, for most people looking to lose weight, is the hormone insulin, and how it essentially directs what happens to carbohydrates in the body.

A key takeaway for the girls here wanting to stop being obese is that insulin, which is stimulated by carbs being eaten, digested, and entering the bloodstream, will have the net effect of locking up that glucose rather than burning it as fuel, and keeping the fat already in the body that ought to be available to burn as fuel, locked up so that it can’t be burned. When I used to go on calorie restriction diets, I felt like I was hungry - starving - all the time.

Taubes and other metabolic scientists helped me understand that this wasn’t psychology or gluttony - my sense of starvation and ravenous hunger was real because I lacked access to the body’s energy stored as fat. It’s what has come to be called the carbohydrate-insulin (resistance) model of obesity versus the calories in / calories out model. The insulin closes off access to your fat to serve as energy - and, yes, you’re ravenous because you don’t have access to energy. And you won’t lose much weight permanently that way, because you can’t really lose weight if you aren’t burning off fat, and insulin in the metabolic pathway makes that very hard.

But science has marched on, and the science of metabolism has started to figure out something long suspected - that ordinary table sugar, sucrose, has unique properties beyond being the most highly digestible carbohydrate. Consisting of glucose and fructose chemically joined, the fructose half of table sugar has uniquely deleterious effects in the body. It’s probably pretty accurate to say that fructose is, all things equal, the most fattening molecule in the mammalian diet. Consumed not as whole fruit with fiber, but instead as sweetened beverages - not just soft drinks, but also as liquid fruit juices - it is a huge “obesogen.”

The biochemical and metabolic role of sugar in the body, as well as sugar’s social, cultural, and economic role in global obesity and metabolic disease, is the topic of “The Case Against Sugar.” The book goes deep into the metabolic science, but the takeaways are pretty clear, even if you’re a high school student and even if you hate math or science.

[mehmetyildizmelbourne-blog]

Nuances of Healthy and Unhealthy Fats with Practical Tips

Eating fat is essential to lowering body visceral fat and staying healthy, but not all fats are healthy. Over the years, I have written extensively about ketogenic diets and the critical role of fat in our health. Recently, I shared an article on the benefits of being fat-adapted, outlining compelling reasons and practical tips for readers.  One of the most common questions I received from new…

[theclovisculture]

Ditch Diets Escape the Weight Loss Rollercoaster for Good

Tired of the weight loss rollercoaster? In this video, Certified Nutritional Therapist Justin Nault reveals why most diets fail and how you can finally stop the cycle of yo-yo dieting for good. Discover sustainable, healthy lifestyle changes that prevent weight regain and promote lasting results. Justin, founder of Clovis and creator of the popular Clovis Daily Superfood Powder, shares his proven strategies for boosting metabolism without extreme calorie cutting.

With over a decade of experience and more than 2,500 success stories, Justin explains how to eat more, exercise less, and still achieve your weight loss goals. Say goodbye to crash diets and embrace smarter, long-term habits that transform not only your body but your entire approach to health.

Whether you're battling a slow metabolism or tired of diet fads, this video is your ultimate guide to sustainable weight loss and optimal wellness. Join the Clovis Culture today and revolutionize your journey to a healthier, more confident you!

Why Watch:

✅ Certified Nutritional Therapist ✅ Specialist in Sports & Fitness Nutrition ✅ Founder of Clovis ✅ Over 2,500 Lives Transformed! 💪

Think of Clovis as your ANTI-MAINSTREAM solution to finally achieving a life filled with health, wellness, and peak physical and mental performance. Most importantly, Clovis brings you… CONFIDENCE!

Clovis is your all-in-one confidence booster for a healthier life!

📞 BOOK A FREE CALL NOW: https://justinnault.com/assessment

Discover how Justin Nault's one-on-one lifestyle coaching and custom nutrition plans can help you reach your full potential. Start your transformation today!

[familydocblog]

Transform Your Health: Strategies to Combat Obesity and Metabolic Syndrome

Feeling overwhelmed by the risks of obesity and metabolic syndrome? Discover practical tips and insights to take control of your health and prevent serious complications. Your journey to a healthier you starts here!

[dynamichealthinsights]

The Health Risks of Consuming High Fructose Corn Syrup

High fructose corn syrup (HFCS) is a staple ingredient in processed foods, playing a key role in the global food industry. It’s omnipresent in soft drinks, candies, snacks, baked goods, and even products marketed as “healthy.” Despite its widespread use, HFCS has attracted significant attention due to its potential negative health effects. As a cheap and versatile sweetener, it has helped the…

[ancientroyalblood]

Understanding Insulin Resistance: Causes, Symptoms, and Solutions

Insulin resistance is a condition where the body’s cells become less responsive to insulin, a hormone that helps regulate blood sugar levels. This resistance impairs the body’s ability to use glucose effectively, leading to elevated blood sugar levels and potentially increasing the risk of developing type 2 diabetes and other health issues. Understanding insulin resistance, recognizing its…