#Fluid Bed Processor

[vjinstruments]

The Fluid Bed Processor : A Comprehensive Guide

Introduction : A fluid bed processor is a type of machinery used in a variety of industries for a variety of purposes. In the most basic sense, a fluid bed processor is a machine that uses a fluid (usually air) to suspend and move particles of a solid material.

Fluid bed processors can be used for a wide variety of tasks, including drying, granulating, coating, and mixing. They are commonly used in the pharmaceutical, food, and chemical industries.

If you’re looking for a comprehensive guide to fluid bed processors, you’ve come to the right place! In this article, we’ll cover everything you need to know about fluid bed processors, including how they work, their applications, and their advantages and disadvantages.

What is a Fluid Bed Processor ? A fluid bed processor is a type of machinery used for various processes, such as drying, granulating, coating, and mixing. This machine utilizes a fluid, such as air, to suspend and move particles of a solid material. The machine has a number of components, such as a blower, filter, and heater, each with its distinct purpose. The blower is responsible for creating a stream of air, which passes through the filter. The filter prevents any solid particles from entering the stream while allowing tiny droplets of liquid to pass through and be carried by the stream of air. This is where the fluidized bed gets its name. The heater is then used to control the temperature of the air stream, thus controlling the temperature of the particles and the desired end results of the process. All of these components together create an environment in which a variety of tasks can be accomplished.

The Different Types of Fluid Bed Processors - Fluid bed processors can be classified into two broad categories – top spray and bottom spray. Top spray is the most common type, and is used for granulating and coating. In this process, the particles are sprayed with a liquid solution from above, causing them to stick together, forming granules or pellets. Bottom spray processors, on the other hand, are used in applications such as drying. Here, the product is sprayed from below, forcing the moisture out of it, resulting in a dry product. Some processors can handle both top and bottom sprays.

The Benefits of Using a Fluid Bed Processor - One of the main advantages of using a fluid bed processor is that it is a relatively fast process. Because the particles are suspended and moved by air, the process takes less time than conventional techniques. Additionally, the uniform movements of the particles ensure that the end product is of consistent quality. Fluid bed processors are also known for their efficiency. This is because the process does not require a lot of energy to complete. Furthermore, the fact that the processes are conducted in a closed environment ensures that there is minimal loss of product to the environment.

Fluid bed processors are an essential piece of equipment for many industries, including pharmaceutical and food processing. They are commonly used to dry, granulate, and coat various materials.

Fluid bed processors can be used for a variety of tasks, such as drying wet materials, granulating powdered materials, and coating particles with a variety of materials. In this guide, we will discuss the basics of fluid bed processors, including how they work and their many uses.

Fluid Bed Dryer Granulator -

A fluid bed dryer granulator is a drying and granulating machine that uses airflow to suspend and separate materials during drying and granulation. The machine is often used in the pharmaceutical and food industries to dry and granulate powders, pastes, and other materials.

The fluid bed dryer granulator works by suspending the material to be dried or granulated in an air stream. This air stream is then passed through a heating element, which dries or granulates the material. The dried or granulated material is then collected for further processing.

The fluid bed dryer granulator is a versatile machine that can be used for a variety of applications. In the pharmaceutical industry, it is often used to dry and granulate Active Pharmaceutical Ingredients (APIs) and Excipients. In the food industry, it can be used to dry and gran

Fluid bed processors are an essential piece of equipment for many industries, including pharmaceutical and food processing. They are commonly used to dry, granulate, and coat various materials.

Fluid bed processors can be used for a variety of tasks, such as drying wet materials, granulating powdered materials, and coating particles with a variety of materials. In this guide, we will discuss the basics of fluid bed processors, including how they work and their many uses.

Fluid Bed Dryer Manufacturer -

If you are in the market for a fluid bed manufacturer, you have come to the right place. VJ instruments are a leading manufacturer of fluid bed systems and have a wide variety of products to choose from. We have a team of experienced engineers and technicians who can help you select the right system for your needs.

Our fluid bed systems are designed for a variety of applications, including drying, cooling, and heating. We have a wide range of sizes and capacities to choose from, so you can find the perfect system for your needs. We also offer a variety of customization options, so you can get the system that is just right for you.

[adinathinternationalindia]

Fluid Bed Dryer R&D Lab Model

Fluid Bed Dryer R&D Lab Model, a compact dryer with a fluidized bed granulation machine, is perfect for pilot scale and R&D lab applications. Its redesigned design makes it extremely adaptable for the food, chemical, bulk drug, pharmaceutical, dye, and polymer industries. The purpose of fluid bed dryers is to evenly dry materials at low temperatures. SS 304, 316, and 316L are used to make all contact parts. A suitable motor, blower, filters, filter bag, and control panel are included with the entire machine. Heating system supplied in accordance with particular client specifications.

We are a manufacturer of R&D fluid bed dryers with five, ten, and twenty liters of manufacturing capacity. Additionally, for pilot lab scale operations, we develop Fluid Bed Processors and Fluid Bed Coaters with spray purging arrangements.

[cozzzynook]

Rodimus having no idea he's a tank carrier because it's so rare and was outlawed way before he was born. Tank carriers are seen as a legend because no one has ever seen one. Because of this Roddy has no idea he is one.

Due to starvation and constant stress his coding has never turned online. But when he's on the Lost Light he feels safe and makes a home for himself. Especially after he bonded to Drift and Ratchet.

His coding activates and he becomes sparked. Except no one knows including himself. He thinks his symptoms are from bad energon, stress, not sleeping enough.

Ratchet knows something is wrong but when he scans him Rodimus comes up as fine because his equipment isn't made for tank carriers.

When he starts showing they all dismiss it as him eating more and no longer starving.

Then one day his valve starts leaking and he feels a horrible cramping feeling. Drift and Ratchet are busy working and he doesn't know what to do.

He lays in bed panicking as energon leaks out and he's in so much pain. He has no idea what's happening to him.

I love this ask so much. I’m making a long fic out of this.

-

The first memory in his processor was not like the first memory of other bots on cybertron.

His very first memory file was deeply embedded and locked within a personal file beneath a personal file that did not belong to him but another he did not know.

Two mechs who he never knew designations of, could not find a single photo or holovid of nor could he ask another who they were.

All he had to go on was this memory chip implanted in his mind with a first view of both himself and two others. A shared memory file, a gesture long passed and well hidden within Nyonian culture he dare not speak to another out of fear of experimentation and functionalist backlash that remained even after the fall of Cybertron.

A mech laying in a bundle of soaked blankets on a hard floor covered in fluids that looked to be in deep pain but smiling at him. As another looked worried beyond possibility as they just as equally gazed down at him touching his helm with a sensitivity he’s never even knew the most delicate wire deep medic to have.

A touch he’s never once felt comfortable giving to another in fear of their reaction.

Their species didn’t call for such delicacy and as such it was deemed an insult to be given. Seen for the weak really.

He didn’t understand what was wrong with him for the two mechs to treat him that way when the second mech that held him was the one in such pain.

His memory core always warmed and saddened at the sight of the two and he’s never been able to figure out why.

All he knows is that the two were whispering words and pushing feelings into his spark that he’s never figured out nor been able to talk about. Rodimus isn’t sure why this memory plays from time to time during the course of his life but it has.

Always at a pivotal moment.

When Nyon fell at his own servos.

When he was shot and killed by Megatron, becoming Rodimus Prime.

When he went to find the knights of cybertron and when he encountered the Djd and time traveled.

The day he almost lost his crew and ship only to bargain for their ability to keep said home on the promise of searching out materials and fuel for Cybertrons restoration and to keep Megatron off world to give their people time to settle and rebuild their lives.

It was a shot in the dark but thankfully his flames were incessantly bright and his finish wasn’t so bad either.

The memory flux always played during pivotal moments, though annoying no Starscream and Windblade and Bumblebee so they’d say yes was not a pivotal memory flux moment. It was a pivotal personal record of his. That particular memory flux only happened when a huge moment was happening.

So why on in the galaxies milky debris was he getting memory flux after memory flux night after night ever since he started fragging conjunx Ratchet and Drift?

The two were conjunx to each other and he was just a fun time short fling that they felt bad for and kept around. He didn’t like saying it out loud or thinking about it but he knew it was true.

The two would grow bored of him eventually and when they did he hoped he could handle it.

Maybe that was why he had the memory fluxs lately?

They were going to leave him.

Maybe he should beat them to it? Rip the adhesives off and get it over with? Play it off so it won’t hurt so bad in the future? Salvage what he could so it wouldn’t be so painful in the long run? Should he just up and leave? No. That might hurt them even if they wanted to be rid of him. Maybe he should just…slowly separate himself? That could work. Right?

He tried excusing himself that same night when the two came back.

He didn’t even make it out the habs door when Ratchet grabbed him by the waist and demanded in his usual grouchy tone for Rodimus to spill what was wrong.

He…burst out in tears after trying to pull himself free of Ratchets grip for a solid five minutes only for Ratchet to lift him with ease and set him on his and Drifts laps on their couch. Drift put two digits on his chin and turned his helm holding optic contact and suddenly he was crying telling them he’ll leave and its okay that they don’t love or want him. He’ll just leave and they never have to think about him again for as long as they live.

That..—that got him a very confused and concerned set of optics and em fields that didn’t know what to do at the sudden burst of emotion coming from their intended conjunx.

Rodimus was able to slip free of their hold and stand but the two were a lot quicker than he was at the moment and they grabbed hold of him before he could run off.

The two of them were completely confused by Rodimus sudden influx of emotions and tears and the insecurity they thought was majority replaced by reassurance.

They can admit they should’ve conjunxed him already but they were truly waiting until they landed on a beautiful planet to conjunx him, not just floating in space. Although, knowing Rodimus he probably would be fine with that. Maybe they should just conjunx and spark bond with him while they floated through space? If thats what it took to assure their intended conjunx and make him happy, they’d do it. But they also knew he deserved more than a rushed mating ritual.

“Roddy, we love you. We don’t want anyone else. We just want to wait until we’ve landed to conjunx you.”

“Kid, please, no more crying. We can talk about this,” Ratchet was not one for tears no matter how many patients he’s seen breakdown, it was never his strong suit. But seeing Drift or Rodimus cry? It physically tore his spark apart.

It seemed Rodimus couldn’t even stop himself from shedding his optics and so the two led him into berth where he curled into the both of them and buried his face ashamed and embarrassed and still so genuinely hurt and afraid. His emotions felt stronger than a normal em field should and Ratchet waited until Rodimus was deep in recharge to scan him fully from the tips of his helm flares to the sole points of his pede tips.

Every single scan he could think on came back normal.

His spark was its usual difference to the average spark readings since his spark was traumatized at what his files describe as a delicate developmental stage. It was an extremely rare occurrence to appear on file and it was never added more detail than that given their government never wanted even their medical staff to know what happened under the circumstances of safety. He’d done some digging once, he found it meant they emerged from the spark with dysfunction. He never got more than that and knew anything else would mean his offlining and so he worked with what he had.

Ratchet informed Drift of his clear readings and Drift looked as if he couldn’t believe what Ratchet was telling him.

“Maybe he needs to see Rung?”

“As if the kid will willingly go to a therapist,” Ratchet rolled his optics as he fought the urge to ignite a smoke tube. “We keep an optic on him,” Ratchet finally said after a long moment, “we can’t be obvious about it either. Don’t want to aggravate whatever this is,” he huffed with a shoulder drop.

For now they knew Rodimus wasn’t in immediate or any danger for all they knew but it was safe to say something was going on and they knew to handle it with extreme care and caution.

In the following weeks they found Rodimus was often tired.

Taking the time to recharge in multiple bursts within his office after actually completing his work, he would curl into a protective ball of sorts and recharge. He abstained from his usual meteor surfing activities which greatly pleased all of his crew but worried Drift and Ratchet past this quadrants moons. Rodimus never liked passing up the chance to meteor surf for anything let alone for recharge.

Multiple scans yet again from Ratchet and nothing.

His spark was still its normal unusual pace and his frame was healthy minus the minor nutrient deficiencies. He was in good health and it bugged the two to no end since they could only watch their intended recharge throughout the day always exhausted and slowing in pace. Rodimus would drop into a deep, snoring sleep that scared the two since he never snored and didn’t wake no matter how hard they shook him.

But no matter how strange this new tiredness was, neither Ratchets nor First aid or Ambulons scanners could pick up anything being wrong with Rodimus.

Eventually the two had to accept that this was a new norm for their intended and so they began to carry a blanket and pillow in their sub space so they could have Rodimus safely recharge on them instead of his desk.

Rodimus didn’t seem to notice how exhausted he always was but the crew did and they expressed concerns to which Ratchet said Rodimus scans were normal. Many figured it was his lack of self care catching up to their captain finally but Drift and Ratchet felt differently. They just didn’t have proof but they just knew it was something else.

Things only became stranger when Rodimus suddenly didn’t like his usual brand of energon anymore. Sure they knew he never really liked any energon specifically since he was so used to starving during the war and when he lived in Nyon. But now he purged at the smell and sight of certain fuel foods, cubes and drinks.

That made Ratchet lay him down in their berth that Rodimus began to pile soft blankets onto that admittedly did make recharge a lot better. Though the two weren’t originally a fan of the pillows they couldn’t say a thing when they saw how comfortable Rodimus slept on them. Especially now that he was purging at the smell and sight of energon he usually never had a problem with.

Rodimus relationship with energon wasn’t the best but that was because he’d consume fuel even if he didn’t like it. Now he couldn’t do that. He couldn’t even be in the same room as most fuels which terrified Ratchet and Drift who immediately noticed Rodimus getting smaller. They were one nano klik away from taking a pod and bringing Rodimus back to Cybertron for Ratchet to do an invasive frame search on him when the two accidentally drank their energon around Rodimus.

The mechs tanks growled something fierce and his optics were becoming static with tears as he looked from their energon to them as he held a servo on his tanks that somehow had a small swell to it even though Rodimus hadn’t eaten in almost a month. They were quick to rush their mugs of energon to him and when he grabbed both and poured both into one mug and drank the fuel eagerly, they were smiling so happily when he was able to finish it and not get sick.

Ratchet did a thorough scan on Rodimus when the mechs back was turned and he was drinking another mix of both Drift and Ratchets fuel in the sword mechs arms while Drift rubbed his spinal strut, Ratchet was shown a clean bill of health. It left him silently fuming as he felt like he was failing Rodimus but Drift gave him a look that told him to focus on their current success of Rodimus finally being able to fuel again.

From that moment the two were more than happy to see Rodimus drinking fuel made for their frame types. He always mixed it saying it was disgusting if he didn’t and neither argued since they wanted him healthy and fueling. So when he began to gain weight in his aft, thighs and tanks they didn’t complain one bit.

Ratchet wasn’t sure why he was gaining weight in those areas only and he wasn’t sure why Rodimus was steadily gaining the most weight in his tanks or why it was round and heavy with no jiggling. He can admit he was happy their intended wasn’t wasting away but he was concerned about Rodimus getting even more tired as he fueled more than before while having mild frame pain.

The frame pain with no readings as to why sent him over the edge making him growl with a deep rev of his engine and he was throwing a wrench through the wall before he knew it. The action scared himself and Drift but it scared Rodimus even more making the mech try hiding his optics as he slightly waddled from the room with an apology.

Ratchet tried stopping their intended but Drift interrupted and told him it was okay.

“This is..stressful and scary..you throwing the wrench through the wall is fine Ratty. But whatever is going on with Roddy.. is making him sensitive..we should give him a moment and you need a moment too just like I do.”

Ratchet hated when Drift was right.

He scrubbed his face plate with his servos and vented heavily. Nodding his helm, Ratchet went to drop heavily onto their couch as Drift went off to the training rooms most likely. For a while Drift can let loose and use his claws and fangs to get his frustrations out while Ratchet can let himself ignite his smoke tube and forget everything for a while.

They were both worried about what Rodimus was doing and they commed Minumus to check the cameras to keep a detailed optic on their intended which was immediately bypassed with Minumus going to sit with Rodimus to keep a much closer optic on the mech since he was worried for him as well.

Rodimus went to the lower decks with Minimus and sat near the heated oil where he felt his frame relax and some of the pain slip free. He told Minimus he could leave which got him a blank stare so he rolled his optics and asked if Minimus could get him the new blend of energon he preferred to which the mech did but ordered him to stay where he was.

Rodimus hated how he had to follow that order seeing as he now needed help to stand since his tank was getting too heavy for him alone to raise himself.

He just really wanted a moment to sort himself and pretend he wasn’t scared. He knew something was wrong with him. He knew it wasn’t normal to be drinking Drift and Ratchets blend of energon that wasn’t made for his frame type and it wasn’t normal to be this exhausted to the point he was tired even after a nap or deep sleep. Not to mention his frame was uncomfortable now and his tank was heavy like something weighed him down.

He wasn’t an idiot, he knew Ratchet was scanning him when his back was turned and when he was sleeping. He knew Ratchet didn’t know what was wrong and he knew Drift and Ratchet were extremely worried about him. He tried not to let his emotions and em field get the best of him but he often couldn’t keep the emotional flux to himself. Ratchet and Drift were incredible at dealing with them but he wished they didn’t have to.

Venting deeply, he shifted his hips a little to try and find a more comfortable position as he dropped his shoulders and sniffled.

He didn’t want to cry right now and he wished he wasn’t stressing Ratchet and Drift out but he couldn’t help it. He didn’t know what was wrong and the memory flux he now had every night was not helping.

It seems the last time he was truly stress free and beginning to fuel at proper times of the day is when this all started. A reward of sorts for following a healthy recharge and fueling schedule was a passionate two days and nights in berth with his intendeds.

He wonders if he somehow messed something up during that time? If he knocked something a-loose or he was sparked?

He laughed at the impossibility of the second option. Ratchet would’ve seen that and he was barren anyway.

Their people had hot spots for sparklings or carried within their spark chamber until it was time for the new spark to emerge and they were placed within their frame that the sire built.

His spark was desolate in that regard.

It wasn’t fit to house another spark and furthermore he didn’t even have the sparkling sub compact spaces. He would never be able to feed them nor grow them.

When he first found out he was…inconsolable and clawing at his frame from crying out of anguish and frustration. He couldn’t understand what he’d done to deserve being barren and he couldn’t fathom why it bothered him so much in the first place. He’d found out during his time living in Nyon and that place was in no way suitable for a sparkling. That same night he was plagued with the memory flux he could not decipher but knew meant something was coming.

Not long after Nyon was destroyed by his own servo at the acceptance of his people.

It hurt.

It still does.

Even now so far from home, cruising along the galaxy further from what he’s done he was pained by his past and the current situation he couldn’t help but feel was his fault even if deep down something was nudging at him telling him it wasn’t his fault.

He placed a servo on his tanks off instinct and allowed himself to listen to that odd buried feeling he recognized as a type of coding coming to light in his processor. He felt it whenever he was near a sparkling but pushed it down and ignored it until he’d forgotten it. After learning he couldn’t have a sparkling he pushed anything to do with them away. It was too painful and while ignoring it hurt he couldn’t help but do it. The fear of exploring it far outweighed his need to divulge in the curiosity.

“Here, Rodimus. Your energon,” Minimus handed him the heavy mug and he gratefully accepted, keeping a servo on his tanks. He felt…at peace and his tanks softened at the gesture and his nerves didn’t feel so high strung anymore.

“I just want to be alone right now Mins. Please?”

There was a moment of quiet that encompassed the room and he was grateful for Minimus sitting further down with his back turned as he began to talk to his own conjunx quietly. He could hear Megatron asking about him and he silently sent an apology message to both mechs who returned it with Minumus telling him vocally not to do so and Megatron responding the same.

Neither faulted him for being, sick? He didn’t exactly feel sick but he felt off and tired while also feeling..normal in a way? Now that he wasn’t purging and could fuel again he felt better, a lot better, but the pains and exhaustion that his weight gain granted him reminded him things weren’t normal.

He consumed his fuel, rubbing his tanks as he sat against the low heat boiler— well low heat for him, he was still a fire mech at spark—and drifted in and out.

Eventually exhaustion won over and he was recharging mostly comfortably until he felt someone place a servo on him and he woke with a mild start shielding his tank with the servo that hadn’t left its spot.

“Its just us kid, its okay,” Ratchet soothed, vocal cords scratchy and deep as always, hints of tube smoke on his breath as he bent down to lift Rodimus up.

Rodimus tried pushing him away and protesting but Ratchet grouched at him making him laugh.

“I’m not that old kid, my knee struts can pick yer aft up easy,” Ratchet smirked as he lifted Rodimus with his knee struts cracking a little. Rodimus felt guilty for having Ratchet pick him up when he felt it should be the other way around but Ratchet flicked his spoiler making Rodimus stiffen and clench his thighs together. Ratchet assumed immediately he was in pain but the moan Rodimus struggled to capture left Ratchet’s optic ridges raising and his dermas lifting with them a moment later.

The scent of slick was wafting into the old medics olfactory sensors and soon he was sending an image capture to Drift who pinged him back not a full klik later ordering they get back to berth where the two could reconnect with their intended and reassure each other that things would be alright.

Minimus was long gone by the time Rodimus was on the elevator with Ratchet nipping at his helm flares making him almost drip beyond his modesty panels.

Drift was right at the elevator doors pouncing the two with greedy fangs that left bite marks on both their neck platings. His servos were about ready to take rodimus and Ratchet apart in the public empty space until Rodimus fidgeted and pushed him forward so they could reach their hab sooner.

“Please,” he moaned once inside their door even as an unknown mech hurried past blushing at their heavy em fields, “please, overload inside me.”

Who were they to deny his sweet cries as they laid him on the berth, mindful of his tanks and sensitive spoiler that fluttered so much it ruffled the sheets and helped him arch up his frame as he slid open his modesty panel. Valve dripping and swollen with slick and charge that tasted heavy and sweeter than cyber nectar during the summer heat.

Drift and Ratchet’s panels retracted so fast it hurt when their spikes pressurized and fanned the warm air.

They couldn’t even get themselves to attempt foreplay with their beautiful intended.

Spikes slipping past swollen folds and deep biolights that glowed impossibly magnificent.

The medical officer in Ratchets coding couldn’t help the subtle scan he did on Rodimus as the mech cried from feeling their spikes slip inside him at the same time. His exterior node just as swollen as his interior nodes, valve cycling down on both the spikes that were struggling not to overload early inside the heated plushy walls that weren’t as tight as he felt they should be. They were warm, wet, swollen and greedily taking everything they had to offer even after months of being untouched.

He wasn’t so lost in the pleasure he couldn’t file that for later but a look from Drift told him he wasn’t as subtle as he’d hoped and he relayed the information. Neither were at all able to stop pumping their spikes inside Rodimus until they were buried hilt deep and the tips of their spikes were touching a wet bulge that opened and allowed them deeper inside.

It was something neither Ratchet or Drift had but Rodimus always had it. The very first time they fragged it scared Ratchet a bit but when he found nothing wrong on his scans he left it alone. Now he wonders if he should’ve investigated it more thoroughly.

“Ah, Ratch, Drift, please, oh- please, overload inside me,” Rodimus cried, writhing on their engorged spikes that pushed roughly into his swollen node and squelching flesh that gave way to the two and only the two.

Ratchet and Drift put their thoughts to the back of their processor as Drift lifted Rodimus’s leg carefully to reach deeper within and make Rodimus lift himself closer to the swords mech who purred. Fangs digging blood from Rodimus’s neck cables as he felt Rodimus and his tanks push into him and grip his shoulder strut so hard he dug his digits until the paint chipped and metallico lightly bled.

Ratchet didn’t appreciate feeling left out and used his digits to tease along the seams of his chassis, both servos finding the hooks and unclasping the tight chest panel that gave way to heavy chest pouches that were swollen and sensitive to the air hitting them.

Rodimus cried out half over loading from the exposure and light brush of his dark nozzle against Drifts plating and Ratchets delicate touch. The medic took note of the changes and something flicked within his optics that he found within Drifts.

They both couldn’t stop themselves from apologizing to Rodimus who cried static as he painfully overloaded the moment Drift buried both his and Ratchets spikes as far as they could within Rodimus valve past the valve caps and into something they’ve only ever felt in Rodimus. As Ratchet gripped Rodimus’s pouches and twisted his nozzles making him release an ocean of charge from his valve and fizzle out his optics from over stimulation.

The two were soft as they kept pumping into Rodimus but they couldn’t find it in themselves to stop as Ratchet checked his systems and helped Rodimus wake up.

Little speedster was fragged past his capabilities that night as he was stuffed with overload making him feel fuller than he now typically did.

Scan after scan on himself and Drift that came back normal with a high in nutrients they were pouring into Rodimus valve was all Ratchet got and all Drifts internal scanners told them. Rodimus’s scans were reading normal with signs of exhaustion that the two felt a little bad about but strict berth rest under Ratchets orders left Rodimus’s readings normal again save for the faint pain readings that Rodimus told them was discomfort.

After that he was confined to the berth and their hab where his tanks grew steadily and it was attributed to him fueling so often and recharging so much.

It was two months later that Rodimus was alone in their hab suite, tanks feeling tight and more than just uncomfortable. He wondered if fragging every day while stuck on berth rest was the reason. He couldn’t help how charged he felt. Ever since they left the lower decks two months ago he was constantly in need of their spike and would cry until he got it. At first it was concerning him but when Ratchet found he was just overly charged but needed nutrients that their frames were overly providing and pumping into him, things were a bit calmer and the two weren’t so on edge.

He was surprised the two finally left to their shifts after waking to Rodimus shifting uncomfortably and struggling to get up to use the wash racks. His tanks were heavier than he liked admitting though the two knew since they’d lift it for him when he stood up to take the weight off for at least a solid klik.

It seemed today that wouldn’t work seeing as it hurt to have either of them touch his tanks.

He actually flinched when Ratchet put a faint digit on his tank to see what was wrong. He groaned shifting away from the mech but asked for his help to the wash rack while apologizing. He didn’t mean to worry them but his waste compartment felt painfully full and his tanks were beginning to cramp into his back plating and his spinal strut was stiff and twitching with bad nerve flares.

He decided to stay in berth after using the wash racks with an audible sigh of relief much to the twos panic.

He was uncomfortable, felt swollen in a way he hadn’t while his frame was changing and his tank felt like it dropped the moment he let himself drop back onto their nest.

“Roddy, we’ll be back within an hour at most,” Drift assured more so himself and Ratchet as Rodimus nodded half way and breathed deeply through the discomfort.

“Comm us immediately if something changes,” Ratchet ordered, it was funny, he was getting so many orders thrown at him when he was co captain of the ship. He couldn’t bother to find the orders anything but endearing since they were worried about him.

“I’m gonna try and sleep,” he told them as he shifted deeper into the pillows that he now used to sleep sitting up since it was too uncomfortable to sleep laying down.

He wasn’t going to be able to sleep, he knew that, but they didn’t. He wanted a moment alone to work through the pain without either of them panicking. He hoped whatever this was would be finished before they came back. Ratchet was heading to the medbay to get the next few days off while Drift was just doing the most important part of his new shift that’d only take thirty minutes at most before he was racing back to their hab.

He felt guilty for making them worry but they told him not to think about that, he took those words to spark when he felt a staggering pulse of pain contract around his hips and across his tanks making him flinch and stutter a vent.

His servos instinctively rubbed circles along the sides of his tank as he vented shakily and slowly laid back into the pillows until he felt another pulse ripple along his tanks and a heavy weight crush against his valve panel that seeped through his modesty panel.

His optics were wide and confused as he felt another pain grip him by the tank and twist at him until he was gripping his own tanks venting harshly feeling as if something within him was strangling his insides with how tight they became.

He punched out a breath of nothing as his windpipe struggled to do anything more but flex at his strained attempts to inhale as his tanks lurched and dropped fully.

He didn’t have a clue what was going on or what was happening to him and he didn’t have time to figure it out when he suddenly felt his tanks squeeze tighter this time before suddenly letting go and his modesty panels slid open without his permission. Releasing a flood of fluids that gushed until it seeped into the berth and made a puddle around him.

He felt his frame getting a momentary break and he rushed the best he could to sit forward but his tanks were in pain and too low for him to do more than shift to his side where he got stuck when another pulse of pain wracked his frame and he felt something within his tanks shift and he punched out a yelp of pain as he gripped the soaked sheets feeling like his insides were being torn apart.

He tried to focus on breathing when the intense feeling came to an end but he could feel another one slowly building and he was cramping in this position so he rocked himself on shaky and weak arms until he was on his servos and knees with his valve burning in the exposed air and moisture coating his frame as he began to overheat.

The pain came in another wave and this time he was slightly prepared as he grit his denta and grunted the best he could as he vented harshly when it was over.

His vision was blurry from tears building and he swayed on all fours as the next intense pain slammed into his frame feeling worse than the last.

The next pulse of pain lasted longer than the others and he wondered for a moment if this is how he would die? Why did it have to be so painful? What did he do to deserve this?

The memory flux he long associated with dread came to the forefront of his processor and he bent down sobbing as he thought this was really how he would die.

He’d die from intense pain until his spark gave out and he would never know what the memory flux meant or who the two mechs who plagued his entire life were or what they were saying.

He sobbed into his arm as he felt another painful pulse ripple through his tank and this time it made his spinal strut seize and he coughed up nothing, struggling to vent as he let his upper half collapse into the ruined sheets and pillows feeling his spark tighten from the ongoing pain and he closed his optics. He didn’t want Ratchet and Drift to see him like this but he didn’t want to die alone. He didn’t want to die at all.

“Oh my sweet spark, I’m so sorry we have to leave you like this,” a voice he didn’t know spoke to him and looking around the room with bleary optics he couldn’t see another bot but the voice persisted, weak as he felt, loving in a way he never knew possible and so comforting he almost forgot the pain he was in.

He felt another large wave of pain crash into his systems and notifications popped on his hud in his native dialect he’d long forgot was different than standard cybertronian glyphs.

His memory flux came to the forefront as he struggled to vent and gripped his tanks as the pain pushed him over the edge to the point he felt he was being ripped from the inside out that he let a strangled yelp turned cry free into the pillow and his arm as his memory continued to play.

Everything was fuzzy and he couldn’t really hear anything beyond the memory flux nor could he stop himself from letting the bond open allowing Drift and Ratchet to feel his pain, knocking them still and breathless as they struggled to gather themselves and their systems that had to reboot from the unbearable torment suddenly unleashed from Rodimus’s end of the bond.

“My sweet spark, you look so beautiful,” the exhausted mech that looked like he did said breathless, while cuddling him in a bundle of blankets, “one day you’ll understand why we had to leave you and one day you’ll be able to decipher this memory we pass on to you. But for now it will only come in silence as a warning for when you need it. Be it good or bad,” the mech that was built like him and carrying a large tank spoke tiredly before kissing his helm with the help of the mech who had his colors.

“We love you so much sweet sparkling. But it’s dangerous now with the functionalists hunting mechs like you and your carrier. So we have to leave you with a trusted amica who will take great care of you, our beloved sparkling.”

The two mechs were crying and kissing him as much as they could like always but this time he could understand what they were saying and it made his spark melt and tighten.

“We love you sweet spark and every time you flux in recharge and see us it’s our warning of safety and love to you. You will only know our words and voice when you have a sparkling of your own so you know whats happening to you sweet spark.”

“We’re so sorry we can’t be there to love and take care of you. We’d give anything to see you grow and give you everything your spark desires. But we were caught and now all we can gift you is life and this memory.”

“My sweet bitty,” the mech the same color as him cried, “i’m your sire and I love you so much.” He sobbed for a new reason as pain wracked his frame, he could half understand what they were saying but the pain was unbearable and he felt something move inside of him that made him terrified and yelp.

“Always know this my love,” the mech who physically looked like him cried, “just know we love you and we never wanted to leave you,” the mech cried as a loud bang sounded and shouting started.

“We love you sweet spark,” the other mech spoke before standing and shooting at a mech who barged in. He watched as the mech who looked like him tried to get up and run only to fall and cry in pain, shielding him.

The mech who was his color shouted and used their frame to shield the two of them and a hole was blown into his spark for his efforts. He cried feeling a piece of him he never knew be ripped away and he watched as the mech holding him pleaded for his sparklings life and to do whatever they wanted with him.

The mechs remained silent and the mech holding him was shot in the helm.

A final act of love was the mech wrapping their arms around him to shield him from the fall.

The memory ended with the sounds of what he now knew to be his cries before ending and he opened his tear stained optics to his berthroom where he was alone.

His professor was half putting together what the memory flux was until he felt another sharp pain ripping his attention painfully and he let out a strangled cry as he felt pressure begin to lower in his tanks and the door burst open to their hab and a rush of pedes barged into the room before halting.

The sounds of vents heaving and the shocked em fields wrapping around him didn’t take his attention for long.

He felt another wave of pain rush him and he gripped the sheets tighter feeling his frame rock at the pain as he tried to alleviate the worst of his pain.

“Roddy!”

Drifts cry and Ratchets heavy pedes broke him from his pain and he felt relief at no longer being alone as he sobbed allowing Ratchet to begin checking his valve panel hearing him curse the worst he’s ever sounded as he let it slip that what came from Rodimus was fluid he didn’t know mixed with blood.

“Frag! Ratty whats wrong with him?!”

“Damnit Drift I don’t know!”

That made the room grow silent as Rodimus panted, accepting Drift lift him up and lean his weight onto the swords mech as he panted. Optics close as he felt a moment of relief.

He felt disoriented, overheated, tired, exhausted and in the worst pain he’s ever felt.

He shifted a little when he felt the beginning signs of pain coming and he knew he couldn’t handle being on his back or sitting half upright as he was so he shifted himself and Drift and Ratchet immediately asked him what was wrong.

“End..bed..end..” He panted the words out hoping they understood and when the two began to carefully move him to the end of the bed, he thanked them the best he could before gripping Drifts servo and squeezing in pain when another painful pulse rippled through his entire body making him grit his denta in a long whine and groan that turned growl at the end.

Ratchet was frantic running scan after scan as Drift tried to tell him to breathe and while he understood, he was tired and overheated and the words weren’t helping. For some reason he felt like he needed to have his knees on the berth and he needed Drift holding his front or at least up there with him.

He was shifting before he realized, stopping when another painful pulse stabbed him this time making him whimper and cry in embarrassment as his waste tanks opened and he pissed himself.

Ratchet was still scanning him frantically and got so angry he ripped the device from his arm and began to feel on Rodimus’s chassis plating near his spark before stopping to help Rodimus shift so he had his knees on the edge of the berth and Drift was holding him from the front while Ratchet held his sides and thats when he felt how tight they were. He’d never experienced anything like this and he was terrified because he didn’t know how to help and he was terrified they were losing their conjunx.

Drift was shedding tears as he tried to soothe Rodimus who held onto him and gripped his servo at the next painful pulse. Something about this one felt different and he was still apologizing out of breath for pissing on himself while Ratchet and Drift were trying to soothe him that it was okay when he felt something kick, actually kick, him from the inside and move down making him gasp out a sob.

He couldn’t breathe out the word, what, fast enough before another heavy strangled tightening gripped his tanks and something in his processor told him to bear down, the same voice of the mech who looked physically like him, and he was suddenly gritted his denta on the next pulse as Ratchet held his sides and Drift his front while holding him up in a close hug.

Rodimus gripped Drifts servo and bore down feeling something move down and he stopped venting as he did so, letting his whole frame sag once he stopped and thats when Ratchet moved down after Drift yelped from how tight Rodimus gripped his hand.

“Kid, whats wrong, talk to me, please,” Ratchet got down and looked at Rodimus valve when Rodimus suddenly bore down again and Ratchet didn’t know what to do so he let him.

He felt Rodimus’s tanks and felt that the top was hard, harder than what was physically possible for their species and he felt fear spike up in him all over again. He was running so many scenarios in his processor that he all but blue screened for a klik when Rodimus bore down once more and screamed, as he put a servo on his valve and his optics popped open with new tears.

“Roddy! Whats wrong?! Roddy?!”

Ratchet gently moved Rodimus servo, the first movement he’s done this past hour that wasn’t bearing down in pain while he sat uselessly behind him watching, and felt along the swollen and painful looking valve only for his optics to bulge out when he felt something.

“Primus! Kid! What is this?!”

“Fuck Ratchet! What is it?!”

“I don’t know! But it’s coming out!”

Rodimus gripped Drifts servo again and struggled to bear down. He was exhausted and the pain was too much. This was too much.

“Kid? Kid! Ya gotta stay awake! For whatever this is ya gotta stay awake!”

“Roddy? Roddy! Wake up Roddy! Come on wake up!”

He groaned feeling the two lower him onto the berth on his back and he whined feeling pain wracking him worse than before as Drift slapped his face plates to wake him up and Ratchet pressed on his chassis opening it up and lifting his nozzles to keep his spark going.

“Tired,” he barely got out as his vision went in and out.

“We know Roddy, we know. But you gotta wake up and then when this is over you can sleep as much as you want but for now you gotta wake up!”

“Come on kid! Don’t do this to us! You gotta wake up kid! You gotta live, please!”

Rodimus felt himself intaking air as Ratchet made his spark strengthen and he felt their tears on his face plates making him open his optics.

He hated seeing them cry and he hated being the reason…maybe he could try one more time?

He pictured the mech who looked down at him with so much love and the mech who first laid eyes on him as the other mech screamed and soon he was screaming too before cooing.

‘Huh,’ his processor felt something click but he didn’t through the exhaustion.

He shifted himself tiredly and with their help he sat up and shakily pulled his legs up and put a servo on one knee when Ratchet lifted them for him and he felt Drift sit behind him, putting his legs beside his to help them stay up. Rodimus gripped his servo and Ratchet stayed near his valve as he put a servo on his tanks feeling how impossibly tight it had become as Rodimus inhaled and pushed.

Pushed as hard as he could feeling something move further down and suddenly it felt like he was on fire the second time he bore down.

He couldn’t stop the agonizing scream he let out.

It didn’t even sound like him.

The sound of it stunned the two mechs with him and before he could apologize or do anything besides let his spark spin, he was pushing again feeling something press against his valve as he screamed bloody murder.

He was sure he crushed Drift’s servo with how tight he was gripping and shaking it but the mech didn’t say anything, just held him and let him crush it as he pushed again and heard Ratchet gasp as if Primus himself had gifted them something wonderful.

“Keep..keep pushing kid! Keep pushing! Its..its..yer almost done Rodimus, oh primus, yer almost done,” he beamed catching the two off guard.

Rodimus was too busy pushing but Drift was able to ask, “ratty? What is it? What is…primus..”

Drift could see past Rodimus since he was the taller of the two and he could see why Ratchet was crying and smiling for an entirely new reason.

With a vocal shattering shout, Rodimus gave the last bit of strength he had into this one last push and he felt the ring of fire covering his valve and frame slip free of him and dropped into Drift’s frame crying from an over abundance of emotions.

Nothing registered to him for a nano klik until he pushed out something that felt squishy and thick and he heard Drift and Ratchet gasp and then…and then a cry rang out in the room. A cry that made him open his optics and start crying for an entirely new reason.

He struggled so much to lift himself but Drift did it for him and Ratchet brought the crying, screaming, flailing, little bundle to him. Allowing him to cradle them in his arms and look at them. Really look at them as he held the reason his frame changed. The reason they worried for a year and some months. The very reason he was in endless pain for so many hours.

A sparkling.

A real, crying, tiny, strong engine sparkling that was all protoform and no metallico just yet.

Flailing little arms and legs in his hold, with unclear optics that looked just like Drifts shape and Ratchets color with beginning helm finials like Drift and heavy weight like Ratchet.

A sparkling.

Their sparking.

“Oh my gosh..Roddy..you were sparked..all this time you were sparked…”

Drift looked at their sparkling like they hung the stars and Ratchet hadn’t stopped crying since he realized.

“We have a sparkling Ratty! We’re sires! Oh my gosh we’re sires!”

Drift’s em field was drowning the room in happiness just like Ratchets and all Rodimus could do was cry in happiness as he held them.

“My bitty,” he sobbed, “you’re my bitty,” he wailed hugging them close. Finally understanding the memory flux.

“I love you so much,” he cried, “I love you so much,” he sobbed, kissing their helm and counting their digits before looking at their spark. It looked exactly like his own.

He felt fear and the two were on guard thinking he was having another when he shared the memory flux through the bond.

They suddenly understood his fear.

It was kept quiet and only high command and first aid knew that Rodimus had just emerged a sparkling from his tank.

The two cleaned their berth as Rodimus held their sparkling, allowing them to feed from Rodimus nozzles that began to leak energon milk. Megatron stood guard outside with Minimus listening on their comms as Ratchet scoured the forbidden archives and found information on tank carriers and how functionalists offlined them all save for a few. They hid their existence and didn’t teach medics about them. Thats why Ratchet couldn’t detect them and thats why Rodimus didn’t know.

Ratchet said a whole slew of words none knew existed and when he left to call the high council, they knew many would disappear for a while.

The crew was alerted that a sparkling was on board but not how they emerged.

Rodimus was immediately confined to berth rest and Ratchet manually checked him over while he was asleep.

Drift was holding their sparkling as Ratchet gave Rodimus an actual diagnosis and planned for a special energon diet to make up for the metals he was low on that their sparkling soaked up.

“He really grew a sparkling and we didn’t even know,” Drift let their sparkling grab hold of his digit and laughed quietly when Ratchet stole their sparkling with a smile.

“They’re beautiful,” Ratchet smiled, going with Drift to lay beside Rodimus who was knocked out cold.

“I’d do anything for them,” Drift smiled, kissing their delicate helm.

“We owe the kid big time,” Ratchet half joked.

“Absolutely,” Drift smiled, inhaling the scent of their sparkling with Ratchet.

A grumble from Rodimus and the two rubbed the side of his tender tanks and he sighed going back to sleep.

“I can’t wait til he wakes up. Then we can think of names,” Drift whispered giddy.

“Let the kid sleep,” Ratchet smiled kissing their sparklings tummy, “he’s more than earned it.”

“Mm yeah,” Drift smiled, “he has.”

-

[cyberrose2001]

AYYYYYY! Do you remember that request I sent a while ago of the Ratchet x Fem reader? Ya know where Ratch gets to frag the reader to blow off some steam?

Reader is Cybertrionan btw if that's okay!

Stress Relief

TFP Ratchet x fem! cybertronian! reader

whoaaa you can tell I started this months ago eheh… apologies for the long wait I hope y’all can forgive me 👉🏼👈🏼

Warnings: oral, dom!ratchet

Word count: 517

18+ ONLY MINORS DNI

“I’ve been waiting all day for this,” Ratchet huffs, tossing you off his shoulder and onto the berth, “Too fraggin’ long, if you ask me.”

You refrain from making a smart aft comment about how he had actually been waiting all week, but you’re too preoccupied with how he’s pulling your hips closer to the edge of the berth.

It’s always the same with Ratchet. He would have a busy week (aka working his processor to near power down), barely seeing him all day, then apologise profusely for coming to berth late. And by that time, you’d already be in stasis, waking up to your frame gently tucked into his while he spoons you. It annoyed you, having to wait days; hell, even weeks sometimes before Ratchet had a chance to lay a digit on you.

But you’ve quickly learned throughout your relationship that the longer Ratchet goes without interface, the harder he fucks.

His digits are pressing into the seams of your hip plating, calculated and efficient with aeons of experience against your frame. A low moan escapes your throat as you feel your modesty panel easily click open. You’re already dripping wet at the anticipation, and it hasn’t gone unnoticed by Ratchet.

“Then why don’t you frag me then, hm?”

“Oh, I intend to,” Ratchet kneels on the ground, two servos keeping your thighs spread as his hot breath teases your valve, “Only if you can suppress your smart commentary and let me indulge in you first.”

You crane your neck as you watch his dermas latch onto your exterior node and subsequently throw it back against the berth with a clang as he starts sucking and flicking against your node. It’s electric and oh so sensitive as he scrapes it against his dentae.

“Oh, Ratchet.” A filthy mewl escapes your mouth, bringing a servo to his helm when he starts drawing slow circles with his glossa, “Please, I can’t- I need-“

“You need what, exactly?” Ratchet lifts his helm from your heat, and primus, your fluid already coats the lower half of his face in a pink sheen.

“Need your spike- ahhn.”

“What do you want me to do with my spike?” A harsh kiss to your abused node sends shivers up your back strut, which turns into clamping your thighs around his helm as he plunges his glossa into you.

“F-Frag… do you need to ask… nghh… so many questions?”

“So impatient, aren’t you?” Ratchet rolls his optics with a groan, either out of frustration for your impatience to hasten things or his desperate need to shove you face-first into the berth, “Turn around, let me see that pretty aft of yours, sweetspark.”

You obey his command, pedes firmly planted on the ground as you bend over the berth. A weak whine vibrates the bed as Ratchet presses your helm into the silky sheets, another servo pushing his engorged spike against your cunt.

“Now be a good femme and stay still for me,” He groans, sheathing his entire spike into you before pressing his body weight against your back, “my little stress toy…”

[mychlapci]

elaborating upon that one anon contributing to my "getaway fucks the primes" anthology

getaway expects rodimus to be bad in bed. everyone has heard the jokes about hot rod being a one and done kind of mech; valve squirting fluids before his partners have even gotten their spikes inside. getaway has even heard that just brushing against rodimus' node will cause him to overload and then he just shoves whatever partner he's got out the door

and considering his last foray with fucking a prime ended with him sobbing in bed and being ridiculed by the rest of spec ops, getaway really really doesn't want a repeat of that whole mess.

so he refrains himself, ignoring the lingering heat that burns in his fuel tank whenever his dear captain sways his hips a little too flirtatiously after a long night at the bar. or the feeling of arousal that consumes his processor when rodimus pouts his lips at megatron during an argument

he's not fucking a prime again, he just couldn't bear the humiliation of being hung out to dry for the second time in a row

but it's so hard to resist. rodimus is hot and he knows it. all of getaway's angry glares and underhanded compliments just get interpreted as invitations and soon enough getaway finds himself being led back to the captain's quarters.

his servos shake and his intake feels dry even as rodimus grinds against him in aborted little thrusts that send vibrations all the way through to getaway's array. he can't keep his hands off that slutty waist and the way that rodimus squeaks when he rubs against a pair of particularly sensitive biolights is enough to trigger both of their panels to fold away

when getaway finally has a look at that plush valve and rigid spike he's in awe. they're both so wonderfully perfect, nicely sized and just big enough that it would feel great to get spiked but not bullied like how it was with optimus

and rodimus treats him well, cooing compliments and praises and taking the time to finger getaway to completion three times before he even begins to slip his spike inside that now loosened valve.

he's so good with rhythm that getaway's processor stops collecting data for a good few minutes and he nearly bluescreens from a bit of grinding against his ceiling node. he wakes up to rodimus' smug, but oh so kind, smile looking down on him as the captain thrusts gently into his dripping valve

getaway almost forgets about his hatred for rodimus that night, almost

-burnt ice anon

yessss Roddy finally putting in the work to put down the rumour of him being a one pump chump. Not that Getaway would ever admit that he had an amazing time in Rodimus's bed.

It was everything he wanted from Optimus, and better... he can't let Rodimus get away with this.

[safety-pin-punk]

Steps To Take Before You Donate:

A guide from someone who works at a thrift store and has seen some things. This is generalized and not specific to the store I work at.

The first step for ALL of these sections is to look at what you have. Is it something you would give to a friend or relative? No? Then don’t donate it. (Examples of things not to donate: moldy clothes, a soiled pair of pants, sticky dishes, broken mirror)

Clothes and Linens (aka soft lines)

Look to see if your clothes are wet, moldy, or have bodily fluids on them. These types of items will end up at the landfill if you donate them. Just save employees the horror and throw away your own garbage

Don’t donate used underwear or socks, but bras are fine

If the clothes are dirty, wash them (please)

If you want to be super helpful to processors, separate halloween costumes and shoes into different bags or boxes. These items all get processed separately in stores

Donate it even if its ‘poor quality’. Clothing not sold in stores gets sent to textile recyclers

All of this applies to linens (such as blankets and sheets) as well

Electronics

If you have any large items, call the store ahead of time to make sure they are willing to take it. Not all stores have big warehouses for large items. If not, try a different store or chain

Check for any chewed on, or exposed wire. Thrift stores can’t sell these items for safety purposes

If you don’t have a wire or charger for the electronic, ensure that it will stay with the item (tape or rubber bands will work well for this) if an item can’t be tested in store to see if it works, it will not be sold in a typical retail store. It will likely be sent straight to an outlet store

If you are planning on donating a TV (small or big) call the store first, some are able to take them and some are not. Check with them first so they don’t have to turn you away after you get there

If the computer doesn’t work completely, donate it anyway, most thrift stores send them to get refurbished and their memory wiped

Books/Media

Do your books have mold on them or are the pages damp? Don’t donate them

Are the disks so scratched up that they don’t play? Don’t donate them

Stores do accept VHS tapes and cassettes!

If you are donating a bunch of loose disks without cases, keep them together in a bag or a box

If you only have a case for a game (NOT DVD), donate it! People actually buy those

Separate your books and media from other items you are donating, as these get processed separately

Shoes (usually sorted into hard lines but may vary depending on the chain)

If your shoes have bodily fluids on them, or even just some left over dog poop, either clean them or don’t donate them. No one wants to touch that

Even if your shoes have been worn to hell and back (and are not gross), donate them! Just like clothes, if they aren’t sold, most stores will recycle them

Do your best to keep pairs together! Either in a box, tie the laces together, or use a rubber band!

(We do actually love getting shoes donated in their boxes - it makes it a lot easier to sort than a giant garbage bag full of loose shoes)

If you aren’t sure what category shoes fall into at the store you are donating to, just ask! We would much rather that than find shoes in unexpected places!

Furniture

Does it require repairs? Don’t donate it, try a local yard sale site instead

Is it big? Call ahead and make sure the store has space for it

Not every store accepts mattresses/beds/bed frames. Call ahead and ask

If you have a rug, has an animal gone to the bathroom on it? Yeah? Don’t donate that

Side note: if you just bought a big piece of furniture from a thrift store, bring some buddies to help you pick it up. And a big enough vehicle. Our donation door workers are still people and can only do so much to move a giant glass table and fit it into your kia soul when you decide to pick it up 30 minutes before we close

Other Items (aka hard lines)

If a baby is meant to sit or lay in the item, we can’t sell that for safety reasons, even if its brand new

Some stores will sell helmets if they are in good condition, but not all stores. Double check before you drop them off

If you are donating dish ware or china, make sure it is washed and clean. No one wants to touch sticky mixing bowls with a mysterious substance inside

Wrap your dishes or any fragile items and place them in boxes, it helps make sure they dont break before they get processed

If its broken, don’t donate it. Think: is this something I would give a friend?

Put your jewelry together and separate from other items. That way we dont only find one earing

No already lit or used candles that are more than halfway gone, find ways to up cycle them, or see if a friend would like them instead!

No one wants your used bedroom toys. Please no. Im begging you just throw them away if you dont want them

If there are nails sticking out of it, or someone could get hurt on it, wrap it and write a note. Same goes for knives. I can’t even begin to express how many times I’ve almost cut off a finger while reaching into a box of donations

Other Tips

If its sticky, wipe it down

If its fragile, put it in a box not a bag

If its sharp, wrap it

If its multiple pieces, tape it or find a way to keep it all together before you donate it

If you aren’t sure if a store will take it, just call and ask!

[unsanitarystation]

nevermind im back-

Different mechs have such different responses to needing to piss on their partners in heat.

You've got those who are driven very strongly by a sense of control and territory who have it go off as a dominance thing. Prowl with his boys is one of those who will piss on Everything. He physically needs to know everything, especially his mates, smell like him. No one else can lay a finger on them. He will bite and snarl and spray waste fluid everywhere. Nothing in the room is safe. He can and will mark the furniture as well.

He will pin his mates down and piss on them. Audial fins and horns are his favourite things to go for when he bites down and wrestles his mates into position. The first thing he goes for is the hips. He grinds his array against his mates' as he voids his tank, getting it into all the seams between panels and sensitive cabling. Then he will wrestle with his mates more to get their fronts, backs, then sits on their faces and makes them lick him clean.

If he gets his way, he will get a chance to do the spiking and fill his mates full of piss before pumping them full of his transfluid too. Pushing his spike into a valve full of his own hot fluids drives him crazy.

Then you've also got mechs who are really just full of piss and really not much else. Sure their mate gets marked in the process but like yea thats whats supposed to happen and it doesnt have to be done intentionally. Like Rodimus would just be filled to the brim with waste fluids and it would feel good. He'd feel so full and stuffed and the moment he's touched he can't hold it and he's just voiding anyway. He's a whimpering mess laying in a pool of his own waste as he's begging to be fragged stupid. When he's finally impaled on that spike he's coating that thing in his piss.

He's just constantly leaking. His frame is producing the waste and he lets it out. Every thrust into him is an obscenely wet squelch through too much lubricant and fresh waste fluids that trickle out of him.

He practically screams when his mate puts his mouth on his valve, licking and swallowing the mix of transfluid and slick and piss. In his heat-addled processor, where he wants everything to smell like his piss, I dont think theres anything more arousing than his mate drinking it, putting that waste inside him- His mate will be coated inside and out with his scent. What more could he ask for

hghrgh yes exactly... It's a control thing for Prowl. His hab-suite, his office, his two mates belong to him and he needs to make sure everyone can tell.

Roddy on the other hand would just be a mess. He can't control his waste tank and doesn't care to try. He'll pee constantly as he's getting fucked, pussy spraying every few minutes...

I wonder about other bots.

I think it would be a control thing for Drift as well, but he'd be so ashamed of it, feeling predatory for wanting to claim Ratchet... he'll end up sneaking out of the berth at night to secretely piss over the furniture to inject his scent all over. Of course Ratchet notices quickly and coaches him through heat cycles 101, feeding him plenty of energon so he doesn't burn out and lets him mark him whenever he can. I think Ratchet would be begrudgingly accepting of his urges while in heat. He'll be sluggish and feverish, letting piss flow freely out of him as he rolls in the bed. He really likes to pee on Drift's face. It's a pussy eating kind of week when Ratchet is cycling.

Oh, you know Minimus has some strong ideas about marking. Turbofox instincts drive him crazy while his own pride restrains him from giving his body what it needs. He'd probably try to plug himself up. And when he cannot handle it, he'll secretely, shamefully leak into his chair...

Megatron would either never let anyone know when he's cycling, or he'd make a show out of it, use it as an intimidation tactic by pissing on his soldiers to let them know they belong to him... of course, on the lost light he can't quite afford to do that, but I think it would be kind of funny if he tried to mark the bridge and the captain's chair. it would make Rodimus sooo mad.

[thunderwetter]

The Steady Drop - Vampire! First Aid - Teaser

Oops it 5 AM, guess who wanted to go to bed at 3 but got a little distracted.... Anyways, snippet from that Energon-Siphoner First Aid One Shot He's a little creepy but listen, you get attached when you try to repair the same guy for years and smell his Energon every time you work on him. Aid is holding back and I think that deserves some praise kkkkkk

// First Aid, at this moment, was rewiring the leg of an Autobot who had been here for several years now, remaining comatose this entire time. Something about having a regular to fiddle on soothed First Aid’s processor and calmed him down whenever Ambulon was making him nervous or Pharma was on one of his weird monologues again. This patient was his safe haven, his comfort zone. Ironic, to be the only vaguely sane one. He was surrounded by such talented medics, yet they were too blind to recognize what was wrong with their peer. What unfixable condition he had. The mask protected his secret. It was absurd, even macabre, to feel so serene despite the oral fluid pooling in his intake, despite the longing feeling in his fuel tank, despite the ache in his dentae and the hunger that grew the longer he stared at the body before him. The wires felt nice against his fingertips, inviting him to indulge in his vice. He both cursed and thanked Primus for giving him the sensitive servos of a medic. No, the gratitude was definitely more fitting. He was grateful for his profession, for being as good as he was. There were better medics, sure, but this patient was his and he tended to him with as much loving care as he could. He wanted to see him open his optics and see who fixed him. He wanted to hear the praises and thanks. He wanted to be able to ask for a favor, just a small one, just a few drops of Energon. Primus, it had been too long since he had fed from a living, from a reactive frame. He could sink his teeth into him now, drink from the source and nobody would know. The puncture would be hidden. The thought sent an ache through his fangs. He dismissed it, soldered the wiring together and tested the connectivity. The foot moved ever so slightly. First Aid smiled behind his mask. Progress. //

[neocorp012]

Granulation Lines Manufacturer

Neocorp is one of the best granulation lines manufacturer in India. We offer a wide range of granulation equipment including high-shear mixers, fluid bed processors and dry granulation systems. Our granulation equipment is the highest caliber, delivering outstanding performance and functionality. With our expertise and commitment to excellence, we provide a granulation lines that surpasses industry standards and meets your production needs.

[midseo]

Fluid Bed Dryer, Fbd Dryer Manufacturers, Suppliers, India

Pharmax Engineers : Manufacturers, Suppliers and Exporters of Fluid Bed Dryer, Fluidized Bed Dryer, Fluid Bed Processor, Mumbai, India.

Fluid Bed Dryer, Fbd Dryer, Fluid Bed Drying Machine, Fluid Bed Dryer Machine, Fluid Bed Dryer Price, Fluid Dryer Bed, Fluid Bed Dryer Manufacturers, Fluid Bed Dryer Suppliers, Fluid Bed Dryer Exporters, Mumbai, India.

[vjinstruments]

A small display of additional laboratory machinery, including a VJ Instruments pelletizing machine.

For decades, scientists have used the y- maze to study rodents' ability to learn and remember complex spatial layouts. It was first used in the 1940s as a cheap and easy method of investigating the mental capacities of rodents. Drugs like amphetamines and scopolamine were tested for their effects on spatial learning and memory in the earliest studies using the y- maze.

The y-maze is widely used as a rat behavioral test. Their ability to remember where things are concerning one another and events in their immediate surroundings is tested using this method.

The y-maze has three arms that are set at 120-degree angles from one another. Each of the three arms of the y-maze—the "start," "goal," and "choice"—represents a different branch of the maze. The rat is dropped off at the beginning of the maze and given a certain amount of time to find its way out. To test the rodent's spatial learning and memory, researchers monitor and analyze its every move. Both the total number of entries and the total time spent in each chamber are recorded. Different objects and motivational rewards are placed in the arms, and the experiment is often repeated multiple times under varying lighting conditions and other manipulations.

It is common to practice using the y- maze test to identify spontaneous alternation in rodents, which is the rodent's tendency to switch between the maze's arms. A high rate of spontaneous alternation is indicative of good spatial working memory because it shows the rodent is aware of and able to switch between the two arms. VJ Instruments come up with instruments like fbd fluid bed dryer, double cone blender & ball mill in pharmaceutics.

Reference memory, the rodent's capacity to recall the precise location of a previously encountered stimulus in the maze, is another metric utilized in the y- maze test. Typically, researchers will put some sort of enticing treat, like food, into one of the arms and then count how many times each participant chooses to enter that arm as a test of this theory.

Researchers have used the y- maze test to examine the effects of aging, Alzheimer's disease, schizophrenia, and depression on rodents' brains and minds. Antidepressants and cognitive enhancers are just two examples of drugs that have been tested for their effects on spatial working memory using this method.

The y-maze has been used for years to investigate many different aspects of spatial learning and memory.

The y- maze has also been used by scientists to learn more about the neural and molecular mechanisms underlying spatial memory formation and how aging, brain damage, and genetic mutations affect spatial cognition. Dopamine and acetylcholine are two examples of neurotransmitters that have been investigated in the context of spatial memory using the Y-maze. The y-maze has also been used to investigate the function of the hippocampus and the entorhinal cortex in spatial memory. The y- the maze is still widely used in cognitive neuroscience and neurobiology studies because of its effectiveness in studying spatial memory and learning in rodents.

To sum up, the y-maze is a popular rodent behavior test that measures spatial working memory, spontaneous alternation, and reference memory. Various neurological and psychiatric disorders, as well as the effects of various medications on spatial working memory, have been investigated with its help.

 Another rodent behavior test using an elevated plus maze (EPM).

Anxiety-like behavior and its modulation by drugs, hormones, and genetic manipulations are commonly studied in rodents using the Elevated Plus Maze (EPM), a common behavioral test. The elevated plus maze is shaped like a plus sign (with two open arms and two closed arms), with a central platform raised above the ground. The open arms are unenclosed, while the closed ones are boxed in on three sides. The rat is put in the middle of the maze and given the freedom to roam wherever it pleases. The rodent's behavior is monitored and analyzed for signs of anxiety by tracking its every twitch. Mice and rats, by nature, prefer enclosed, dimly lit spaces to open ones. To investigate actions similar to anxiety in rodents, scientists use the elevated plus maze.

Anxiety-like behavior in rodents can be studied with the elevated plus maze, which is both straightforward and economical. Numerous studies on the mental and biological underpinnings of anxiety have incorporated its use. Anxiolytic drugs, which help people feel less anxious, have also been evaluated using this method.

 VJ Instruments offers a selection of pelletizing machine & ball mill in pharmaceutics

In the pharmaceutical industry, materials that are typically powdered or granulated are pelletized using a pelletizing machine. Drug delivery methods other than tablets and capsules, such as oral, nasal, and pulmonary, can also make use of these pellets.

Single-screw extruders, twin-screw extruders, and rotary drum pelletizers are all examples of pelletizing machine types. There are benefits and drawbacks to each type, and selecting a machine comes down to the task at hand and the material being worked with. Spheronizers, holt melt excluders, die roll extruders, and screw extruders are just some of the ball mill machine are also available from VJ Instruments.

When searching for an excellent supplier of mazes and other similar behavior instruments, look no further than Vj Instruments. To learn more about our mazes, including the t-maze, y-maze, elevated plus maze, and more, please visit our website. Additionally, we provide research and development tools, transdermal machines, pre-clinical instruments & fluid bed processor. Our firm's main area of expertise is in the manufacturing of scientific instruments used in the pharmaceutical and preclinical research industries. We stock a wide variety of high-quality items that are both compliant with quality standards and designed with "ease of use" in mind. The actual manufacturing, software development, and R&D that we conduct regularly inform our knowledge of market conditions, technological developments, and client preferences. To learn more, please stop by our website at vjinstruments.com.

[adinathinternationalindia]

Fluid Bed Dryer FBD

Fluid Bed Dryer, also known as the Fluidized Bed Dryer, is a highly adaptable equipment suitable for use in the pharmaceutical, food, dye, chemical, bulk drug, and polymer industries. Its current design makes it excellent for use in production scale, pilot scale, and R&D lab applications. It also includes a fluid bed granulation machine. The purpose of fluid bed dryers is to evenly dry materials at low temperatures. SS 304, 316, and 316L are used to make all contact parts. A suitable motor, blower, filters, filter bag, and control panel are included with the entire machine. Heating system supplied in accordance with particular client specifications.

From 10 liters for small fluid bed dryers to 2000 liters for industrial fluid bed dryers, we produce fluid bed dryers. Additionally, we produce fluid bed processors and fluid bed coolers with spray purging setups.

[bhagwatipharmacom]

High quality and efficient #FluidBedGranulators for high productivity in #Pharmaceutical Industries.

To know more Visit: https://www.bhagwatipharma.com/fluid-bed-granulator-coater-processor/

[indiantradebirddigital]

Fluid Bed Dryers Manufacturer in India

At Indian Trade Bird, we provide the best prices on fluid bed dryers. Fluidized bed processors or dryers, lab-scale fluid bed dryers, vibratory fluid bed dryers, GMP fluid bed dryers, and many more types of dryers are among the products we make, supply, and export in the highest quality. One common piece of process equipment used to lower the moisture content of food, pharmaceutical, and chemical powders and granules is the fluidized bed dryer, also known as the fluid bed dryer. Utilizing these machines has several advantages, including total automation, superior performance, fast production rates, and the highest quality output.

For more details clicks here - https://www.indiantradebird.com/product/fluid-bed-dryers

[vjinstruments426]

Advancements in Pharmaceutical Manufacturing: Plethysmometer, Fluid Bed Processor for Granulation, and FBD Fluid Bed Dryer

The pharmaceutical industry is a realm of constant innovation, with new technologies continually transforming manufacturing processes. Three such advancements that have significantly impacted the industry are the Plethysmometer, Fluid Bed Processor for Granulation, and FBD Fluid Bed Dryer.

Plethysmometer

The Plethysmometer is an essential instrument in pharmaceutical research, particularly in the field of inflammation and edema studies. It operates on the principle of water displacement caused by the swelling of an organ or tissue. The Plethysmometer provides accurate and reliable measurements of inflammation, making it a valuable tool in the development and testing of anti-inflammatory drugs.

Fluid Bed Processor for Granulation

The Fluid Bed Processor for Granulation is a key piece of equipment in the pharmaceutical manufacturing process. It combines the processes of drying, granulation, and coating into one operation. The processor works by suspending particles in a stream of air, creating a fluidized bed. A granulating fluid is then sprayed onto the particles, causing them to agglomerate into granules. The Fluid Bed Processor for Granulation is known for its efficiency, consistency, and the high quality of granules it produces.

FBD Fluid Bed Dryer

The FBD Fluid Bed Dryer is another crucial piece of equipment in pharmaceutical manufacturing. It is used for drying granules, crystalline, coarse or fine materials, and plastic resin. The dryer operates by creating a fluidized state for the material, which increases the contact surface between the material and hot air, resulting in efficient and uniform drying. The FBD Fluid Bed Dryer is appreciated for its high drying efficiency, operational simplicity, and the superior quality of the dried product.

Conclusion

These three technologies - the Plethysmometer, Fluid Bed Processor for Granulation, and FBD Fluid Bed Dryer - have greatly enhanced the efficiency and quality of pharmaceutical manufacturing. They represent the industry’s commitment to technological innovation and the continuous pursuit of excellence in delivering safe and effective pharmaceutical products.

[instrumentsbyvj]

Complete Guide of All Pharmaceutical R&D Equipment

Coating Machines

Efficient Small-Batch Tablet Coating Solution for Pharmaceutical R&D.

The Pharma R&D Tablet Coater is a groundbreaking, self-contained film coater designed for smaller trial batches of tablets and granules. Its sleek exterior is made of durable SS 304 stainless steel, and it features a precision-coating pan positioned at a tangential angle of 35° to 45°, ensuring efficient and uniform coating for pharmaceutical research and development.

pharmaceutical research and development – the R&D tablet coating machine.

The R&D Coater is a versatile and semi-automatic unit designed for pharmaceutical research and development. This integrated system comprises a stainless steel coating pan, a precision spraying system, a hot air blower, and an efficient exhaust system. It harnesses the rotary motion of the coating pan to gently tumble the tablets or granules contained within it. Inside the pan, strategically placed baffles tilt the contents to ensure uniform and efficient coating.

For film coating, a specialized spray gun is employed to disperse finely nebulized droplets of the coating solution onto the moving bed, ensuring consistent coverage across all tablets. To complete the process, a stream of hot air is directed onto the tablet bed, with the exhaust temperature ranging between 60°C and 80°C, enhancing overall performance.

The advanced control panel offers precise control over various settings, including temperature and rotation speeds, allowing for tailored adjustments to meet specific research needs. When introducing tablets or granules into the pan or retrieving them, a scoop should be used. The optimal parameters for coating should be determined through experimentation and trials, ensuring the highest quality results in pharmaceutical research and development.

Fluidized Bed Processor

The Fluidized Bed Processor is a versatile solution tailored for the research and development needs of various industries, including pharmaceuticals, chemicals, food production, and academic institutions like pharmacy colleges. Its primary functions involve coating and drying pellets, allowing for a wide range of applications, such as:

Color Modification: Altering the color of pellets for specific requirements.

Improved Taste: Enhancing the taste of pharmaceutical or food products.

Modified Release: Achieving controlled and modified release forms.

Moisture and Oxygen Protection: Safeguarding products from environmental factors.

Granulation Machine

A rapid mixer granulator is a pharmaceutical equipment designed for the efficient mixing and granulation of powders to produce uniform and high-quality granules. It plays a crucial role in the pharmaceutical industry, particularly in tablet manufacturing. The key components of a rapid mixer granulator include a cylindrical mixing bowl, an impeller, and chopper blades. The mixing bowl accommodates the dry powders or granules, and the impeller provides rotational movement, creating a vortex within the bowl. Simultaneously, the chopper blades introduce additional shearing forces, breaking down agglomerates and ensuring thorough mixing.

The working principle of a rapid mixer granulator involves a series of sequential steps to achieve optimal granulation. Initially, dry powders or granules are loaded into the mixing bowl. As the impeller and chopper blades rotate, they create a controlled and dynamic mixing environment. A liquid binder is then added to the rotating powder bed, leading to the formation of wet mass. The impeller and chopper blades work together to break down any lumps, disperse the liquid binder uniformly, and induce granulation. The resulting granules exhibit improved flow properties, uniform size distribution, and enhanced compressibility, making them ideal for subsequent tablet compression processes in pharmaceutical manufacturing.

Fluid Bed Top Coater

A fluid bed top coater is a pharmaceutical processing equipment designed for coating granules or particles with a thin layer of coating material. This coating process is commonly used in the pharmaceutical industry to enhance the properties of the granules, such as taste masking, controlled release, or protection of active ingredients. The equipment consists of a perforated bed through which air is blown, creating a fluidized bed of granules. The coating material is sprayed onto the fluidized granules, ensuring even distribution and uniform coating.

The working principle of a fluid bed top coater involves several steps. Initially, the granules to be coated are placed in the fluidized bed. Air is then introduced at a controlled rate, creating a fluidized state where the granules become suspended and behave like a fluid. This fluidized bed provides an ideal environment for uniform coating. The coating material, often in the form of a liquid solution or suspension, is sprayed onto the fluidized granules through a nozzle system. The fluidized state ensures that each granule receives an even and consistent coating. After coating, the granules are dried by continued airflow until the desired coating thickness is achieved. The fluid bed top coater's efficient and precise coating process is crucial for achieving the desired pharmaceutical product characteristics.

lab-scale fluid bed dryer

A lab-scale fluid bed dryer is a small-scale version of the industrial fluid bed dryer and is widely used in laboratory settings for drying, granulating, and coating small quantities of pharmaceutical or chemical materials. It operates on the principle of fluidization, where air is used to fluidize and suspend particles, creating an efficient drying or coating environment. The equipment typically consists of a drying chamber, a perforated bed, a fan system, and controls for temperature and airflow.

In its working process, the lab-scale fluid bed dryer first places the material to be dried or processed on the perforated bed within the drying chamber. Air is then forced through the bed from below, causing the particles to become suspended and behave like a fluidized mass. This fluidized state allows for efficient heat transfer, leading to rapid and uniform drying of the material. The temperature and airflow are controlled to achieve the desired drying conditions.

For coating applications, a liquid coating material can be sprayed onto the fluidized particles, ensuring a uniform and controlled coating thickness. The lab-scale fluid bed dryer is advantageous for research and development purposes, allowing scientists and researchers to experiment with different drying or coating parameters on a smaller scale before scaling up to industrial production.

Lab-Scale Extruder & Spheronizer Combo

Lab-Scale Extruder and Spheronizer Combo is a seamlessly integrated system poised to redefine granulation in formulation research and product development. The Extruder component, featuring four interchangeable heads, facilitates versatile low-pressure granulation techniques on a bench-top scale, accommodating batches as small as 200 grams. Its adaptability and indicative results make it a cost-effective and efficient solution for evaluating diverse formulations.

Complementing the Extruder, the Spheronizer component offers precise control over spheronization processes, featuring a substantial 230 mm diameter friction plate capable of producing spheres ranging from 0.5 mm to 10.0 mm. With user-friendly features such as easy disassembly, GMP design, variable plate speeds, and a dedicated stainless steel control panel, this dynamic duo empowers researchers and product developers to seamlessly progress from extrusion to spheronization, unlocking new possibilities for innovation in pharmaceuticals, chemicals, and the food industry. The Extruder and Spheronizer Combo stand as a cohesive and powerful platform, representing a significant leap forward in granulation technology.

Lab-Mini Screw Extruder: Tailored Solutions for Pharmaceutical Pelletization

A mini screw extruder is a compact and versatile piece of equipment used in laboratories or small-scale production settings for extruding and processing various materials. It operates on the principle of using a rotating screw to push, melt, and shape materials into a desired form. This equipment is commonly employed in the plastics, food, and pharmaceutical industries for tasks such as compounding, mixing, and forming different shapes.

In its working process, the mini screw extruder takes raw materials in solid or pellet form and feeds them into the extrusion chamber. The rotating screw applies heat and pressure, causing the material to soften and take on the desired shape as it passes through the die. The mini screw extruder's compact size and adaptability make it a valuable tool for small-scale experimentation and development of new formulations or processes.

Lab Mini Spheronizer

A Mini Spheronizer is a laboratory-scale equipment used in pharmaceutical and chemical industries for spheronization, a process that involves shaping and rounding extruded material into spherical pellets or beads. It operates by rotating a disc at high speeds, causing the extruded material to form spherical shapes through constant rolling and friction.

Hot Melt Extruder

A Hot Melt Extruder is a compact apparatus used for pharmaceutical and polymer processing. It employs heat to melt and extrude materials, facilitating the production of solid dispersions, implants, or controlled-release formulations. This equipment is particularly useful for processing thermolabile substances by minimizing exposure to high temperatures.

Die Roller Extruder

A Die Roller Extruder is a machine designed for the continuous extrusion of various materials, including plastics and pharmaceutical formulations. It consists of rollers that compress and shape the material as it passes through the die. This extrusion process is widely utilized in industries where continuous and uniform shaping of materials is essential, allowing for efficient production of consistent profiles or forms.

All-Purpose Mixing Machine

An all-purpose mixing machine in the pharmaceutical industry is a versatile piece of equipment designed to efficiently blend various ingredients, such as powders, granules, or liquids, to achieve a homogeneous mixture. It plays a crucial role in pharmaceutical manufacturing processes, contributing to the production of formulations like tablets, capsules, and suspensions. These mixing machines are adaptable to different batch sizes and offer flexibility in accommodating diverse formulations and production requirements.

The working principle of an all-purpose mixing machine involves the integration of a mixing vessel or bowl, agitators, and sometimes choppers or blades. The dry or liquid components are loaded into the mixing vessel, and the agitators create rotational or shearing forces to ensure uniform distribution of the ingredients. Choppers or blades may be employed to break down agglomerates and further enhance mixing. The speed and duration of the mixing process are controlled to achieve the desired level of homogeneity. The all-purpose mixing machine is crucial for maintaining product quality, consistency, and meeting regulatory standards in pharmaceutical manufacturing.

A Table Top Transdermal Patch Machine

A Table Top Transdermal Patch Machine in the pharmaceutical industry is a compact and specialized apparatus used for the production of transdermal patches. These patches are designed to deliver medication through the skin, providing a controlled and sustained release of the active pharmaceutical ingredient. The table-top version is typically smaller in scale, making it suitable for laboratory or research settings where small batches of transdermal patches can be developed and tested.

The working principle of a Table Top Transdermal Patch Machine involves the precise combination of drug-containing adhesive layers, backing materials, and protective liners. The machine applies pressure and heat to laminate these layers, ensuring a consistent and reliable transdermal patch. The compact design allows for ease of use in smaller-scale experiments, making it a valuable tool for researchers and formulation scientists.

Advanced TDP & ODF Machine Pilot Scale

An Advanced TDP & ODF Machine Pilot Scale is a sophisticated piece of equipment used for the development and production of transdermal patches and orally disintegrating films (ODFs) on a larger pilot scale. This machine integrates advanced features to handle increased production volumes and maintain precise control over the manufacturing process. It is crucial in the pharmaceutical industry for scaling up the production of transdermal patches and ODFs, both of which are innovative drug delivery systems.

In operation, the Advanced TDP & ODF Machine Pilot Scale follows a similar principle to the table-top version, involving the precise assembly of multiple layers and the application of pressure and heat to create transdermal patches or ODFs. The advanced features of this machine enhance efficiency, accuracy, and scalability, making it an integral part of the pharmaceutical manufacturing process for these specialized drug delivery systems.

Maze Master Software Interface and Digital Plethysmometer 

Behavioral instruments such as the Maze Master Software interface and Digital Plethysmometer play crucial roles in experimental setups focused on assessing and quantifying animal behavior in research settings. The Maze Master Software interface is a tool designed for managing and analyzing data from behavioral experiments conducted in mazes. It provides a user-friendly platform to control maze environments, record animal movements, and analyze behavioral metrics. Researchers can customize experiments, track parameters, and obtain valuable insights into aspects like learning, memory, and spatial navigation.

The Digital Plethysmometer is an instrument used to measure changes in blood flow and volume in small animal extremities, often tails, for assessing peripheral perfusion. This device aids in studying vasomotor responses and is particularly valuable in cardiovascular and pharmacological research. The plethysmometer records changes in limb circumference or blood volume based on alterations in infrared light transmission. Researchers can use this data to understand vascular reactivity and evaluate the effects of various interventions on peripheral blood flow.

Both instruments contribute significantly to the field of behavioral and physiological research by providing accurate, reproducible, and quantifiable data essential for understanding various aspects of animal behavior and physiology.

Radial Arm Maze:

The Radial Arm Maze is a widely used behavioral test in neuroscience and pharmacology to assess spatial learning and memory in rodents. It typically consists of a central platform with multiple arms extending radially. Each arm is baited with a reward, and the subject, usually a rat or mouse, learns to navigate and remember which arms contain the rewards. The working principle involves the rodent relying on spatial cues to efficiently locate and retrieve the rewards while avoiding previously visited arms. Researchers analyze the choices made and the time taken, providing insights into cognitive functions, memory, and spatial navigation abilities.

Morris Water Maze:

The Morris Water Maze is a classic spatial memory and learning test for rodents, particularly mice and rats. It comprises a large pool of opaque water, with a hidden platform submerged just below the water's surface. Animals learn to locate the hidden platform using spatial cues around the room. The working mechanism involves the subjects forming a cognitive map of the environment and adjusting their strategies over trials. Researchers measure parameters like escape latency and path length, offering valuable data on spatial learning, memory consolidation, and cognitive flexibility. The Morris Water Maze is a versatile tool in neuroscience for studying various neurological conditions and the effects of pharmacological interventions.

Open Field Maze:

The Open Field Maze is a commonly used apparatus in behavioral research to assess general locomotor activity, exploration, and anxiety levels in rodents. It consists of a large, open arena with defined zones. The working principle involves placing the animal in the center and allowing it to explore the environment freely. Researchers observe and record behaviors such as distance traveled, time spent in the center versus the periphery, and grooming activities. The Open Field Maze provides insights into anxiety-related behaviors, locomotor activity, and the effects of pharmacological interventions on exploratory behavior in preclinical studies.

Elevated Plus Maze:

The Elevated Plus Maze is a well-established test for evaluating anxiety-like behavior in rodents. The maze features two enclosed arms and two open arms elevated above the ground, creating an approach-avoidance conflict. Animals, typically rodents, are placed on the central platform and can choose between the open and enclosed arms. The working mechanism involves the innate tendency of rodents to explore novel environments while balancing the fear of open spaces. Researchers measure parameters such as time spent in open and closed arms, entries into each arm type, and overall exploration behavior. The Elevated Plus Maze is valuable for studying anxiety-related disorders and assessing the anxiolytic or anxiogenic effects of pharmaceutical compounds.

T-Maze:

The T-Maze is a classic apparatus used in behavioral neuroscience to investigate spatial learning and memory in rodents. Its structure resembles the letter "T," with a stem and two arms forming the crossbar. During a trial, an animal, often a rat or mouse, is placed at the base of the stem and given the choice to turn left or right. One arm is typically baited with a reward, while the other remains unrewarded. The working principle involves the rodent using spatial cues to remember and choose the correct arm containing the reward. Researchers analyze the animal's choices, latency to make a decision, and memory retention, providing valuable insights into spatial cognition and memory processes.

Y-Maze:

The Y-Maze is another widely used apparatus for assessing spatial working memory and spontaneous alternation behavior in rodents. It consists of three arms forming the shape of the letter "Y," and animals are allowed to explore the maze freely. The working mechanism involves the innate tendency of rodents to alternate between the arms during successive entries. Researchers record the sequence of arm entries and analyze the percentage of spontaneous alternations as an indicator of spatial working memory. The Y-Maze is particularly useful in preclinical studies to investigate the effects of drugs or genetic manipulations on short-term memory and spatial cognition.

Zero Maze:

The Zero Maze is a specialized apparatus used in behavioral research to assess anxiety-like behavior in rodents. It consists of a circular platform elevated above the ground with two enclosed areas and two open areas. The circular design aims to create a conflict between the natural exploratory behavior of rodents and their aversion to open spaces. The enclosed areas offer a sense of security, while the open areas induce anxiety. The working principle involves placing the animal in the center of the maze and monitoring its preference for exploring the enclosed or open sections. Researchers analyze parameters such as time spent in open and closed areas, entries into each zone, and the overall anxiety-related behavior. The Zero Maze is valuable for studying anxiolytic or anxiogenic effects of drugs and understanding the neural mechanisms underlying anxiety.

Light/Dark Box:

The Light/Dark Box is a widely used apparatus in behavioral neuroscience to assess anxiety-like behavior in rodents, primarily mice and rats. It consists of two compartments: one brightly illuminated (light compartment) and the other dark and enclosed (dark compartment), connected by an opening. The working mechanism leverages the rodents' natural aversion to brightly lit and open spaces. Animals are placed in the dark compartment and given the choice to explore the light area. Researchers monitor behaviors such as time spent in each compartment, entries, and latency to enter the light area. The Light/Dark Box provides insights into an animal's response to conflicting motivations of exploration and aversion, making it a valuable tool for studying anxiety-related behaviors and evaluating the effects of pharmacological interventions.

Aesthesiometer

An aesthesiometer is a medical instrument designed to measure an individual's sensitivity to tactile stimuli, providing quantitative assessments of their sensory perception. It is commonly used in neurological examinations to evaluate the integrity of sensory pathways and detect abnormalities in touch sensitivity. The instrument typically consists of a calibrated rod or filament with a controlled diameter, which is applied to the skin at varying pressure levels. The examiner adjusts the force applied by the aesthesiometer until the individual being tested perceives the sensation. This threshold of perception is then recorded, allowing clinicians to assess and monitor changes in sensory function, particularly in patients with neurological disorders or peripheral neuropathies.

The working principle of the aesthesiometer involves systematically applying the calibrated filament to specific areas of the skin, such as the fingertips or toes, while gradually increasing the force. The individual undergoing the test provides feedback when they first sense the touch, and the corresponding force or pressure required to elicit the sensation is measured. The aesthesiometer allows for precise and reproducible assessments of tactile sensitivity, aiding in the diagnosis and monitoring of conditions affecting the sensory pathways. Clinicians use this information to evaluate the severity of sensory deficits, track changes over time, and tailor appropriate interventions for patients with sensory impairments.