#Comparative Genomic

[shradhacmi]

Animal Genetics Market

Animal genetics provides a fascinating window into the intricate web of evolutionary relationships. Read More: https://cmihelloglow.blogspot.com/2023/06/decoding-blueprint-exploring-wonders-of.html

[lemongogo]

college … wasted on the youth (me)

[shallowseeker]

Is yours the kind of chronic illness you'll recover from? You definitely don't have to answer or give personal details, but I really hope you feel better!

No, it's okay. It's likely that I won't fully recover, but in the past decade, there have been WAY more treatments available that turn down the immune system and combat scarring. And yes, I'm much better, thanks!💖 In a nutshell,

my immune system malfunctioned after an infection, and now it attacks my body in big, big ways—with a tendency to damage the muscles and lungs!

My situation got even weirder because it started attacking my nerves and heart from 2020 onward, which ... usually ppl with my diagnosis, get respiratory failure, not overt heart issues. (Long story, but I got undiagnosed, then rebiopsied, then rediagnosed the same thing *with extra notes.) Anyhoo, the new developments impacted my mobility and stamina in even crazier ways than I was used to. (I have until recently worked a full-time job and pretty much spent ~5-6 days in a gym with an expensive physical therapist just to keep my body functional. Before, I had an acquired skeletal myopathy, but I was able to run a 5k in 42 minutes... I trained like an Olympian and while had to rest a lot more than most, I could do it!)

Now... I can't even manage one day a week of light activity. It's a big adjustment, even for me! I'm having to noodle on how to best manage it going forward. It's always this confusing situation of "Is this the primary illness, secondary damage, or the side effects of toxic medications?"

I'm doing a pretty good job if I do say so myself.

[cbirt]

Scientists have questioned the comparison of genes’ organization across various species. Collinearity analysis is a helpful way to go about this task, although it seems complex at first. Collinearity refers to the situation where related genes are found in identical order as well as in the same orientation on different chromosomes. Studying collinearity is one of the main tenets of comparative genomics, which sheds light on how organisms are related evolutionarily and functionally.

Researchers at the Illinois Institute of Technology have come up with a new software pipeline called SYNY, which has made investigating and visualizing collinearity easier. In this blog post, we will explain what functions this software can perform, discuss its pros and cons, and show how it helps researchers assemble genetic puzzles.

Decoding Gene Order Secrets: Why Collinearity Matters?

Consider two recipe books that stand for the genomes of different species. The ingredients (genes) may vary, but some recipes (functional gene clusters) can be surprisingly similar in both books. It is this similarity in the order of genes and their orientation that collinearity analysis helps to identify.

Continue Reading

[picardsims]

i will be doing simblreen uni is just being difficult

[incirrata]

after tagging my last reblog with "we [computational biologists] sometimes are capable of actual science I promise" I did some data analysis and figured out that the project I've been working on this semester is probably worthless. either the database we're drawing from isn't complete enough or the results of certain genome reconstruction techniques aren't.

[caffeine-high]

my complete inability to read T2T (telomere to telomere) as anything other than T4T (trans for trans) is proving to be a problem

[why-animals-do-the-thing]

Do you have a snoot noodle or other variation of sighthound? If yes, there’s new heart health research for the breed happening!

A researcher at Texas A&M whose work I’m familiar with is starting a new study looking at genetic factors contributing to heart disease in Borzoi and related breeds. They just put out a call for dog owners who are willing to submit saliva samples & (noodle) medical records. Studies like this need a big sample size! They’re accepting new sign-ups starting now until March 1, 2025, for dogs both in the US and internationally.

Let’s help make some science!

From the study page:

“Background and purpose

Recent research in Borzoi dogs has revealed that dogs of this breed experience sudden, unexplained death. About 85% of sudden, unexplained deaths in humans are linked to an underlying heart disease. Our existing research in Borzoi dogs has shown that they are predisposed to developing arrhythmias (abnormal heart rhythms) and dilated cardiomyopathy (a heart muscle disease causing dilated heart chambers and weak pumping function).

Due to our documentation of the frequency of these conditions in Borzoi dogs, we seek to identify responsible genetic variations similar to what is seen in humans with electrical cardiac diseases that trigger arrhythmias and dilated cardiomyopathy.

The objective of our study is to identify genetic mutations associated with heart disease in Borzoi dogs and document their existence in other sighthound breeds.

What happens in this study

We are collecting saliva samples from both healthy Borzoi and Borzoi dogs affected with arrhythmias and/or dilated cardiomyopathy. We will also collect saliva samples from any other sighthound breeds.

We will extract DNA from these samples and perform genomic sequencing on a select number while retaining the remainder for further screening.By analyzing the sequencing data, we can compare the genes of healthy and affected Borzoi dogs and identify variants linked to their heart conditions. We will also compare the findings in Borzoi dogs to results from other sighthound breeds.

Pet owner responsibilities

A swab kit will be sent to you for at home use along with a link to an instructional video on how to properly obtain a swab of the mouth. The kit will contain equipment to collect the saliva swab, a history form for your pet, a client consent form and a shipping label to return samples to us.

Participation requirements

To participate, you must have a Borzoi dog or a sighthound breed that is either healthy or affected by arrhythmias and/or dilated cardiomyopathy. Pets may be any age or sex. Electronic or paper veterinary medical records will need to be provided.

Benefits and risks of participating

There is little to no risk for taking a brief swab of the mouth for saliva collection if procedures outlined in the video are followed. No individual genetic test results will be provided to study participants.

Compensation

There is no cost to the owner for participating in this study. No compensation will be provided.”

[andypantsx3]

𝐢𝐧 𝐚𝐧𝐲 𝐮𝐧𝐢𝐯𝐞𝐫𝐬𝐞 : 𝐭𝐨𝐝𝐨𝐫𝐨𝐤𝐢 𝐬𝐡𝐨𝐮𝐭𝐨 𝐱 𝐫𝐞𝐚𝐝𝐞𝐫

𝐜𝐨𝐧𝐭𝐞𝐧𝐭𝐬: 1.7k of unedited alien prince shouto thoughts based on this post from the other day! sfw, gender neutral reader. several elements of this universe were borrowed from my fave sci-fi novel; see end notes for deets!

he's beautiful—the todoroki prince. tall and strong in his high-collared uniform, strapped with lean muscle and handsomely humanoid. he's the first thing that snares your gaze as your party is guided into the hall of the sun—the reception dome that overlooks the rise of the star yuuei in the morning sky, used by the ruling family to receive visiting dignitaries.

it is morning, in endeavorian planetary time, and the sun has begun to rise. its light is weaker than you remember from back home—almost watery, pooling like quicksilver in the panes of the dome's ceiling.

up at the front of the hall, it catches in the strands of the white half of the prince's hair. from what izuku has told you, it's the half that indicates he's part of the himura bloodline. the himura dynasty has ruled the yuuei system from its capital planet of endeavor iv for tens of thousands of earth-years. it's the second longest line of unbroken rulers in mapped galactic history, an impressive feat.

the other half of the prince's hair is a fiery red, like that of the man who stands next to him—todoroki enji, the general of intergalactic renown, who donated half of prince shouto's genome as well as his clan name. each time a himuran royal from the main line marries, izuku had explained, talking at lightspeed in the podship, they take a branch name, typically sourced from the primary gene-donator. it helps keep inheritance lines clear.

prince shouto looks like he's inherited empress rei and todoroki enji's genes in exactly half—his coloring split down the middle, though his features are perfectly, almost hauntingly symmetrical. he wears a pin of flint at his collar that symbolizes his gender—one of yuuei's thirteen official designations. from what you understand from izuku, it most closely aligns with earth designation "man".

it's embarrassing how much you notice about the prince as you file into the hall, stationing yourself right at the gap between izuku and tenya's shoulders, so you can still see todoroki shouto.

"you don't think they'll reject the treaty and kill us all, do you?" denki mumurs nervously as he presses in behind you.

"no, i don't think so," izuku's gentle voice drifts back to you. he's a three-star ethnologist, studying for a command ethnology post. subsequently he's the most informed of any of the cadets that have been sent along with the treatise party. you and denki are just mechanics, sent along in case anything goes wrong.

"the alliance would be too much trouble for the yuuei," izuku explains. "they have good relations with the surrounding galaxies and tight control over a lot of resources. but the alliance is really large now, compared to the last time they approached the yuuei. they'll likely want to accept at least a loose federation with the allies."

up on the platform at the front of the hall, prince shouto blinks long and slow, like an earth cat. you realize with a start it's the first time you've seen him blink at all, and the subtle reminder that he is not just an extraordinarily handsome human man but the prince of an alien species makes your skin prickle.

"don't you think it's weird they are all this pretty?" denki asks. "it's weird, right?"

"definitely weird," you laugh, your eyes trailing over prince shouto's blade-straight nose, his pert, perfect mouth. "possibly illegal under intergalatic law."

prince shouto stills all of a sudden, and there is the tiniest tilt of his head. two heterochromatic eyes flick over your way, and you are completely embarrassed by the way your stomach swoops in response. you just manage not to grab onto tenya's uniform to steady yourself.

one of the prince's eyebrow arches almost imperceptibly, and you wonder if he's heard you from this distance—but no, that would be insane.

denki picks up his commentary, emboldened by your playing along. you think the prince's eyes linger just a little too long on the gap between izuku and tenya's shoulders, but then you're distracted by the reception beginning.

the alliance treaty officer strides forward, flanked by a few of the other officials your crew had ferried here. she performs an elaborate bow, as do the other officials. from izuku's muttering you gather it's some sort of ritualistic greeting, and empress rei at least looks pleased with it, waving a gentle hand to gesture the party forward.

there is some shuffling as various aides set up a table and a series of holo-tablets, along with various inks, a leathery roll of endeavorian traditional parchment, and—

"is that a knife?" you ask, peering at the long obsidian blade placed on the table in front of the officials.

izuku's fluffy head of green curls inclines. "treaties are sealed twice. once in the alliance fashion and then again in the local custom, to make it binding per both systems. blood pacts have been used in yuuei for millennia."

the brush of something over your face has your gaze turning back to the prince—to find him staring straight at you, those unblinking eyes boring into you.

"izuku, weird question. can the yuuei hear across rooms?" you ask, suddenly self-conscious.

a green eye peers back at you. "only in the event of their pair bonds—the yuuei are documented hearing their matepair across approximately ten earth-kilometers. i think we're safe over here though. why?"

matepair. the world settles strangely under your skin, as the prince's eyes brush across it.

"uh, matepair?" you echo.

tenya gives both you and izuku a quelling look, but it's not enough to deter izuku from ducking down to explain in slightly quieter tones. "the yuuei look human but they pair differently. they form a parapsychic bond with only a single partner, which they maintain and uphold for life. it's not just cultural—it's like a physical compulsion. they cannot take another pair, and they cannot be separated for long periods or they grow sick."

prince shouto is still staring straight at you, and it's not quite comforting enough to know that he cannot possibly hear you.

it's only his role in the ceremony that seems to eventually break the prince's weird focus in your direction. he steps forward to perform his duty as empress rei's chosen heir. you almost flinch as the knife draws across the pale skin of his palm, and he adds several drips of silvery blood to the parchment, symbolizing yuuei's intent to uphold the treaty across future monarchs.

the flesh of his palm knits itself back together in seconds, and another little shiver goes up your spine. those mismatched eyes flash back your way as he steps back, and the various aides and officials once again converge on the documents.

there is a brief flurry of activity, various bows and oaths, some stilted endeavorian verse. the chief treaty officer looks relieved when it's all over, and the royal family steps down from the dais to greet the rest of the visiting party, as is the customary honor granted to allies to the yuuei. tenya ushers you into the queue near the back with denki, a symbol of your lower status as mechanics.

you don't mind, as the thought of reaching prince shouto has your stomach doing what feel like backflips in your gut. the longer the delay the better.

izuku had walked everyone through the appropriate greetings on the podship, a few murmured words and a hand touch at chest-level—extremely hard to mess up, even for you. but nevertheless your pulse kicks up the closer you draw to the royal family.

there's a long line of them you greet first. offshoot branch members, then general todoroki enji, whose enormous palm burns hot against yours and who looks he'd rather take your party's hands off than touch them. then rei's unchosen heirs—the princess fuyumi, prince natsuo—and a gap where prince touya would have stood, were he not offworld.

and then you're standing in front of prince shouto, your pulse pounding in your ears. he's extremely tall up close, clearing six feet easily, broad across the shoulders and handsome in a way that almost makes your teeth ache. the yuuei look deceptively human, but this near you can see the tiny details that separate them from you—the slight double-point to their ears, the silvery undertone to their skin, the prolonged space between their breaths and their blinks.

and of course their inhuman beauty. they don't quite look like regular people, and it sparks a tiny note of wariness in the primeval part of your human hindbrain.

prince shouto's mismatched eyes pin you, silver and blue, as a sudden, silvery flush creeps across his face. you hold your hand out in greeting, trying not to wonder if you've somehow managed to offend him already—but instead of pressing his palm against yours, his long fingers suddenly grasp yours, clasping tightly.

beyond him, empress rei freezes too. all at once you can feel every single himuran noble turn to look at you, hundreds of eyes pinning on you.

reflexively, words tumble out of you. "shit did i—what did i do? were you supposed to get a different hand thingy?"

you can hear the treaty officer's horrified inhale at the terms shit and hand thingy, deployed in crass galactic standard in front of a literal prince. you immediately wish you could take them back, but from the look on the prince's face, he's already heard them.

something at the corner of his mouth twitches, like he's trying not to smile.

"y/n," he says, in a deep tone. it's crisply accented and just as beautiful as the rest of him.

it takes you a second to realize prince shouto has used your name, which he could not possibly know considering the uniform you'd been issued for the yuuei visit has no unique identifiers on it. you glance down at yourself, then back up at him, befuddled.

"how did you—? where did you—?" you garble out. "did denki put you up to this? how do you know me?"

prince shouto's fingers smooth over yours, delightfully warm, calloused and sure. "i would know you in any universe," he says, voice soft. behind you, you hear princess fuyumi make a tiny sound of delight.

you blink. "universe? what—uh, what universe? how would you—?"

but shouto leans in, tugging you closer with those deceptively strong fingers. he's so very warm up close, and so beautiful it makes your brain short circuit, especially as he lowers his face to yours. a shiver rolls down your spine as his other hand takes you gently by the chin.

and then he murmurs a single word before pressing his mouth to yours—

"matepair."

𝐞𝐧𝐝 𝐧𝐨𝐭𝐞𝐬: credits where they are due!! the idea of a space general dna donator, an overarching space alliance pursuing a treaty, & the flint pin denoting gender were taken from my fave sci-fi novel winter's orbit by everina maxwell! (if you love heartfelt gay love stories in space i am actually begging you to read it).

[hellsitegenetics]

As Gregor Samsa awoke one morning from uneasy dreams he found himself transformed in his bed into a gigantic insect. He was lying on his hard, as it were armor-plated, back and when he lifted his head a little he could see his dome-like brown belly divided into stiff arched segments on top of which the bed quilt could hardly keep in position and was about to slide off completely. His numerous legs, which were pitifully thin compared to the rest of his bulk, waved helplessly before his eyes.

String identified: A Gg aa a g a a ta t a ggatc ct. a g a, a t a-at, ac a t a a tt c - t t ac gt t c t t c a t a a at t ct. g, c t t ca t t t , a .

Closest match: Rangifer tarandus platyrhyncus genome assembly, chromosome: 28 Common name: Svalbard Reindeer

[max1461]

Thinking about this post. "The only way to make a cell is from another cell" is somewhat of a troubling fact to me. I mean, not for any practical reason, just because it underscores the precarity of *gestures broadly*.

It's like, some people talk about trying to de-extinct the mammoth. And people are trying to sequence the genome of the mammoth, I don't know if they've done it yet. But even if they do, one of the problems with the idea of de-extinction is... to grow a baby mammoth, you need another mammoth! Last time I heard people talking about this, I think they were talking about using an elephant as a surrogate mother. But imagine if elephants were extinct too.

The point is that information is often tied to the systems that transmit it; even if you know everything in the mammoth genome, once all the mammoths are gone there's nothing capable of reading and using that information. Like when you can't read the data on a perfectly good floppy disk because your computer doesn't have a floppy drive.

This is related to why language death troubles me so much. Even the most well-documented languages aren't actually that well understood; linguists have produced more pages of work on English syntax than maybe any other specific descriptive topic and yet still the only reliable way to get the answer to any moderately subtle syntactic question is elicit native speaker data. We know almost nothing, we can barely extrapolate at all! And every language is like this, a hugely complex system that we know basically nothing about, and if the chain of native speaker transmission is ever broken it's just gone.

"Language revival", I mean from a totally dead language, is kind of a myth. It's like the "came back different" trope. In Israel they revived Hebrew, but Modern Hebrew is really not the same thing as Biblical Hebrew at all. I mean in a stronger sense even than Modern English isn't Old English. All the subtleties of Biblical Hebrew that a native speaker would have had implicit competence with died without a trace. All they left is a grainy image, the texts. The first generation of Modern Hebrew speakers took the rough grammatical sketch preserved in these texts and imbued it with new subtleties, borrowed from Slavic and Germanic and the speakers' other native languages, or converged at by consensus among that first generation of children. There's nothing wrong with that, but it would be inaccurate to imagine Biblical Hebrew surviving in Modern Hebrew the way Old English survives in Modern English. For instance, you can discover a great deal that you didn't know about Old English by comparing Modern English dialects. There is nothing you can discover about Biblical Hebrew by comparing Modern Hebrew dialects in this way.

There's nothing wrong with this, of course. I'm not like, judging Modern Hebrew. I'm just making a point.

Mammoths died recently, so we still have (some of?) their genome. Something that died longer ago, like dinosaurs, we have traces of them in the form of fossils but we could never hope to revive them, the information is just gone. Even if we're not aiming for revival, even if we just want to know stuff about dinosaurs, there's so much that we will never know and can never know.

We imagine information as the kind of thing which sits in an archive, because this is the context most of us encounter information in, I think. Libraries, hard drives. Well obviously hard drives don't last. And most ancient texts only survive because of a scribal tradition, continuous re-writing, not because of actual archival. So I think that imagining archives as the natural habitat of information is sort of wrong; the natural habit of information is in continuous transmission. Information is constantly moving. And it's like one of those sharks, if it ever stops moving it drowns. And if the lines of transmission are broken, the information is gone and can never be retrieved.

Very precarious.

[blueiscoool]

A Mummified 44,000-Year-Old Wolf Found in Siberian Permafrost

Scientists perform necropsy on an ancient wolf pulled from Russian permafrost that may still have prey in its stomach.

In a first-of-its-kind discovery, a complete mummified wolf was pulled from the permafrost in Siberia, after being locked away for more than 44,000 years. Scientists have now completed a necropsy (an animal autopsy) on the ancient predator, which was discovered by a river in the Republic of Sakha — also known as Yakutia — in 2021.

This is the first complete adult wolf dating to the late Pleistocene (2.6 million to 11,700 years ago) ever discovered, according to a translated statement from the North-Eastern Federal University in Yakutsk, where the necropsy was performed. The discovery, scientists say, will help us better understand life in the region during the last ice age.

Photos from the necropsy show the wolf's mummified body in exquisite detail. Animals are preserved in permafrost through a type of mummification involving cold and dry conditions. Soft tissues are dehydrated, allowing the body to be preserved in a frozen time capsule.

Researchers took samples of the wolf's internal organs and gastrointestinal tract to detect ancient viruses and microbiota, and to understand its diet when it died.

"His stomach has been preserved in an isolated form, there are no contaminants, so the task is not trivial," Albert Protopopov, head of the department for the study of mammoth fauna of the Academy of Sciences of Yakutia, said in the statement. "We hope to obtain a snapshot of the biota of the ancient Pleistocene."

He added the wolf, which tooth analysis revealed was male, would've been an "active and large predator," so they will be able to find out what it was eating, along with the diet of its victims, which "also ended up in his stomach."

Another key aspect of the necropsy is looking at the ancient viruses the wolf may have harbored. "We see that in the finds of fossil animals, living bacteria can survive for thousands of years, which are a kind of witnesses of those ancient times," Artemy Goncharov, who studies ancient viruses at the North-Western State Medical University in Russia, and is part of the team analyzing the wolf, said in the statement.

He said the research project will aid their understanding of ancient microbial communities and the role of harmful bacteria during this period. "It is possible that microorganisms will be discovered that can be used in medicine and biotechnology as promising producers of biologically active substances," he added.

The wolf necropsy is part of an ongoing project to study the wildlife that lived in the region during the Pleistocene. Other species examined include ancient hares, horses and a bear from the Holocene. The team plans to study the wolf's genome to understand how it relates to other ancient wolves from the region, and how it compares to its living relatives. The team now plans to start studying another ancient wolf discovered in the Nizhnekolymsk region of northeast Siberia in 2023.

By Hannah Osborne.

[nerdykorgi]

GRIMWALKER BIOLOGY & ANATOMY STUDIES [pt 1 / ?? ]

(aka, my ideas and thoughts on how these bad but sad boys work!)

with pictures :D !

ok for starters! I tried my best to make real life connections with actual biological stuff and yeah but there are some things ima have to bullshit lol

i hope yall like rambling

[ ^ Basic ideas ]

Lets talk about anatomy!

From what i can tell from the grim walker ingredient book they have some pretty ... interesting ingredients...

GALDORSTONE:

Heart and Power apparently. What i can make of this is that the Galderstone not only powers and animates the non-organic materials but acts as a circulatory system, flowing blood and nutrients to keep the body stable by creating magical pulses of pressure that makes the blood flow. Blood is kind of ideal for homeostasis and living and om pretty sure we've seen hunter bleed at least once... Perhaps the Galderston can create an artificial vascular system to carry oxygen, magic, and nutrients throughout the growing body instead of just making veins from scratch. I want to say the Galderstone can generate energy for the grimwalker but that would mean they wouldn't need to eat, and I don't think that's true. I think its main purpose is just activate the magic materials and is like the generator to a car, keeping it running. If the Galderstone were to break or fail, the grimwalker probably come unglued and fall apart to its components (which would be pretty horrifying)

ORTET BONE:

Very key component! The ortet bone kind of helps form the blueprint for the species of the grimwalker, as well as supplying blood, a skeletal system, and components of DNA. The most basic definition of the word ORTET is as follows: the original plant from which the members of a clone have descended. Fun fact: since were using cloning terms, Hunter is to Caleb as Ramet is to Ortet (Ramet is an individual clone) I did research for cloning and as it turns out you kinda need a complete genome for cloning but for bullshitting reasons (which will be explained) we can clone with incomplete DNA and make synthetic dna from scratch! I hypothesis that the reason grims can look different from the ortet instead of just straight carbon copies is due to the bone that is used and how much of i there is. Like example a grimwalker made using just a toe phalange is going to look A LOT less like the ortet compared to a grimwalker made from something like the cranium and bigger bones and such. Basically smaller bones dont carry as much dna info and leads for room to fill in the blanks. Sadly this means alot of Grimwalkers had A LOT of health problems (this can range anywhere from immune system problems to liver failure which is quiet typical in clones, that and it is often that clones appear different from the ortet due to enviromental factors and influences)

[ As the image above shows, subject #103 has a very close resemblance to the ortet due to the bones that are used ] There are pros and cons to using bones! Pros being that they can hold DNA for much longer than tissue, but the thing is bones can degrade really easy if not preserved, and i don't think belos had a bottle of hydrogen peroxide laying around that he could dunk Caleb in, so let's just assume he made sure his brother's corpse was well cleaned and kept. Biggest con is the human body only has so many bones (about 206) I believe that the reason Grimwalker can generate organs is by using the ortet and making the stem cells created from bone marrow. Stem cells are very important because they can turn into different types of cells like blood and tissue cells as well as repair tissue. I believe the process of growing grimwalkers is kind of like "Self-renewal" the process in which stem cells divide and make more of the body

STONESLEEPER LUNGS:

Im just gonna assume stone sleeper had very small lungs because aint no way those t rex lungs fit in a teenage boy. I originally thought The reason that Grimwalkers can stay underground for so long is because the lungs, similar to how a stonesleeper hibernates for centuries (kind of like how wood frogs can basically cryo-hibernate) by petrifying but a grimwalker IS growing and therefore needs resources to grow, like how a baby does in the womb. So it has to be actively getting said resources so it cant be petrified. I now think the reason that grimwalkers have these lungs is because theyre easily compatible to the galderstone, which needs oxygen for the blood and that they can be easily harvested and stored in stone form. But that does give room for cool adaptations like self-petrification! (which i will get into next time :D )

PALISTROM WOOD:

Ok its says that the wood is used for keratin, which is a fiberous protein which can make all kinds of things like scales, hair, nails, feathers, horns, claws, hooves, and skin! And since its also a plant means it can grow 4 times as fast as normal keratin can! This explains why hunters hair grew so ridiculously fast in season 3, was because his hair can produce its own carbohydrates and nutrients on its own... This means his skin and surface wounds can heal quite fast! (down side is it might give him something similar to PSS (Peeling Skin Syndrome ) ...) I think Palisman is very important becasue of several reason! 1 Like palisman, it can "animate" if you will, more or less help pull off the illusion that he is alive. 2 Like mentioned before, Grimwalkers need nutrients to grow and I believe the palistrom wood aids in that! Using a process called cellular diffusion, the grimwalker can take in nutrients from the ground around them (which i theorize to be highly fertilized) through THEIR SKIN! and into the veins and flesh of the grims 3 I believe that in the process of forming, the galderstone "activates" the palistrom wood, forming into skin or hair but this process of rapid growth leaves the skin all undone and fragile because a proper cutaneous barrier was not formed yet (which is useful for being malleable. This is why Hunter's ears are so 1 .god blessed big because they are fake and molded to look like that. Its also why The grimwalker Belos possessed fell apart so easily, like he said "It wasnt ready")

SELKIEDOMUS SCALES:

This one kind of confused me because... well why do we need the seal flesh when the ortet can just regenerate it?? I think its kind of like the stuffing if you will, it also speeds up the process of producing flesh by a lot! Especially if you want to make grown grimwalkers! Im thinking that Grimwalkers don't have a set "age" theyre just as big as however many materials they are given to work with. Even though the book says they can start as babies, if you look closely there is a check mark towards the more adolescent figure, so im thinking that they are not ready to be unearthed until they reach a certain growth ima guess around the age of over 10-ish?? We don't know how young Hunter was pulled out of the floor but it seems like he was fairly young, or atleast younger. This means while Hunter appears to be 16, he might have only been living for around 5 years or so.

Now typically normal seals have a lot of blubber which is a thick layer of fat, also called adipose tissue, directly under the skin of a marine mammals. Its used for insulation. The thing is tho, it says Selkiedomus Scales, not flesh... Dont worry there are mammals that have scales like Pangolins but i dont know if these scales are like thick plated or small and stretchy. Magic bullshitting time, Im goin to assume Selkiedomus scales refers to a layer of scale-like flesh that protect the creature from boiling but is also highly malleable and easy to work with. Maybe the reason they can withstand such heat is due to unsaturated bonds of butadiene molecules mixed into the blubber that are highly heat resistant Selkie domus flesh is molded and into the relative shape of desired body and using the DNA of the ortet the flesh is reshaped and reused into the desired muscles shapes. The vascular system created by the galderstone spreads throughout the flesh and binds with it. healing together and becoming flesh, kind of like a speed up version of skin graft maturation! This is useful for growing them quickly because they don't have to grow an entire adult body from scratch so this speed up the process by eeeerrm 20 years or so lol

Thats only the basics for now, sooner or later i shall get into the more fun stuff, like adaptaions of Grim walker, the growing process, ad more!

Hope you guys enjoyed my ideas, if i got anything incorrect let me know, my research isnt exremly searched through.

last question ill leave you all with, it kind of stumped me while i was working...

i have a theory but i wanna know your thoughts...

(i worked hard on all this btw, i really hope people read it lol /lh.)

[kedreeva]

I love bug's little yellow patch under her eyes do your other birds have them too? Also is there a name for it and does it come in other colors or just yellow? Sorry I'm not that informed about peafowl though I do love your birds and what you post about them lol

It doesn't have a name because it's just a phenotype indicator of a hybrid. Bug has a low percentage of green peafowl blood in her lineage (pretty much all "blues" in the USA are actually low percent Spaldings, and likely Europe and Australia at least as well by now, hybridization is wreaking havoc on peafowl genomes everywhere, including wild green populations being found with blue DNA because people release hybrids to their native ranges). Wild blues may have a VERY small yellow star at the rear corner of their face mask, behind their eye and above their ear, but the green blood can cause this to spread due to the yellow and blue face mask on greens.

Compared to blues where the yellow is nearly or actually non-existent (and may even be a sign of hybridization in wild populations as well!) and the face mask is white, with blue only immediately circling the eyes

It's pretty, but the yellow isn't actually a good thing, due to what it indicates. Still there's not really a way around it at this point, considering the state of the genetics pool across the world, so it's one of those things I aim to decrease but am not going to complain about since it can't be helped except maybe by time travelling to slap the person that started hybridizing and the people who supported it at the outset.

Which is sort of an answer to your other question- yes most of my other birds have it to some degree or another but not nearly as drastic as Bug's is.

[covid-safer-hotties]

Boy! That natural immunity for covid sure is ramping up!

Evaluating the risk of SARS-CoV-2 reinfection with the Omicron or Delta variant in Wales, UK - Published Sept 6, 2024

Abstract

Recent studies suggest an increased risk of reinfection with the SARS-CoV-2 Omicron variant compared with previous variants, potentially due to an increased ability to escape immunity specific to older variants, high antigenic divergence of Omicron from earlier virus variants as well as its altered cell entry pathway. The present study sought to investigate epidemiological evidence for differential SARS-CoV-2 reinfection intervals and incidence rates for the Delta versus Omicron variants within Wales. Reinfections in Wales up to February 2022 were defined using genotyping and whole genome sequencing. The median inter-infection intervals for Delta and Omicron were 226 and 192 days, respectively. An incidence rate ratio of 2.17 for reinfection with Omicron compared to Delta was estimated using a conditional Poisson model, which accounted for several factors including sample collection date, age group, area of residence, vaccination and travel status. These findings are consistent with an increased risk of reinfection with the Omicron variant, and highlight the value of monitoring emerging variants that have the potential for causing further waves of cases.

If we had "lasting natural immunity" to covid, this last sentence would not be what scientists are finding. Covid (especially omicron derived variants, e.g. ALL THE ONES CURRENTLY IN CIRCULATION) has evolved to be excellent at immune escape. Anyone telling you that an infection is as good as a vaccination is a liar dealing in dogma, not science. Mask up to prevent the spread to keep the virus from mutating so rapidly so that we can actually build up some worthwhile lasting immunity through vaccination.

[hirkyy]

the disconnect western commies that defend russia have with actual current russian rhetoric is so unreal, russian state tv will be comparing ukrainians to an infection and vermin and openly talking about "flawed ukrainian genome" that needs to be exterminated while americans live in some sort of mass hallucination where it's about nato akshually and not genocide.