#Chandipura virus in India

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Top news of the day: Mamata Banerjee says Bengal Assembly will pass bill seeking capital punishment for rapists; ED fines DMK MP Jagathratchakan ₹908-crore in FEMA case

Trinamool supremo and West Bengal Chief Minister Mamata Banerjee addresses a gathering during the TMC Chhatra Parishad (students wing) foundation day celebrations in Kolkata on August 28, 2024. | Photo Credit: PTI Mamata Banerjee says Bengal Assembly will pass bill seeking capital punishment for rapists West Bengal Chief Minister Mamata Banerjee on Wednesday (August 28, 2024) said that a session…

[isacopraxolu]

India, è allarme virus Chandipura: “Colpisce il cervello dei bimbi” #chandipura #virus #tfnews #7agosto

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Un patogeno torna ad allarme in India. Il virus Chandipura (Chpv), trasmesso da pappataci e zecche, può causare febbre con dolore articolare, sindrome di Reye (rara forma di encefalopatia acuta) e paralisi cerebrale infantile. L'India ha confermato 51 casi in diverse regioni del Paese, soprattutto bambini. Uno studio internazionale in fase di pubblicazione, coordinato da Francesco Branda, Unità di Statistica medica ed epidemiologia molecolare dell'Università Campus Bio-Medico di Roma, ha creato una piattaforma per monitorare i casi e dare un quadro globale completo dell'epidemia in corso con risposte tempestive e coordinate. I sintomi inizialmente assomigliano a quelli dell'influenza, ma possono progredire rapidamente fino all'encefalite, al coma e alla morte entro 24-48 ore, colpendo soprattutto i bambini di età inferiore ai 15 anni. Non è ancora chiaro il meccanismo attraverso il quale il virus entra nel sistema nervoso centrale. Tuttavia, si ritiene che produca una fosfoproteina nelle cellule cerebrali entro 6 ore dall'infezione, il che potrebbe spiegare la sua rapida letalità. Sfortunatamente, non sono disponibili farmaci antivirali o vaccini. Il controllo dei vettori, l'igiene e la sensibilizzazione sono le uniche misure disponibili contro la malattia. L'obiettivo del lavoro è armonizzare le informazioni raccolte, garantendo che i dati provenienti da diverse fonti possano essere efficacemente confrontati e combinati. E' stata quindi creata una piattaforma per monitorare i contagi in diversi stati e pianificare risposte rapide e concertate. Partendo dal virus Chandipura, i ricercatori hanno creato l'Health Data Southeast Asia, che mirerà a raccogliere e integrare dati dettagliati sui virus emergenti e riemergenti in Asia. In questo modo sarà disponibile una piattaforma centralizzata per l'analisi epidemiologica e genomica, consentendo il monitoraggio in tempo reale della diffusione e delle caratteristiche di questi agenti patogeni.

[hotnew-pt]

Qual é o vírus mortal 'Chandipura' que afeta a Índia? #ÚltimasNotícias

Hot News La comunidad médica india está en alerta, después de que el estado occidental de Gujarat informó de 137 casos sospechosos del virus Chandipura (CHPV), según informaron las autoridades locales según recogió el diario Indian Express y la Agencia EFE. El Hospital Civil de Rajkot, en esta misma región, reveló al diario indio que hasta ahora se han ingresado 20 niños en una sala especial…

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Monsoon mayhem grips South and Southeast Asia | WION Fineprint - WION

Monsoon mayhem grips South and Southeast Asia | WION Fineprint  WION Nipah, Chandipura are just tip of the iceberg  Hindustan Times Kerala Nipah Outbreak Contained Through Coordinated Efforts  Outlook Planet Nipah virus is caused by bats that infect fruits: Can fruits lead to this deadly virus infection  The Times of India ‘Four more people test negative for Nipah’, says health minister Veena…

[unfilteredindia]

Chandipura Virus Encephalitis: A New Pandemic?

#chandipuravirus #pandemic #virus #Chandipura

[dwaherbals]

Chandipura Virus, Chandipura Encephalitis, Arbovirus, Rhabdoviridae, Vector-borne Disease, Sandfly-borne Virus, Neurotropic Virus, Viral Encephalitis, Emerging Infectious Disease, Public Health.

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from India | The Indian Express https://ift.tt/2NW2otS

[audiopedia2016]

What is CHANDIPURA VIRUS? What does CHANDIPURA VIRUS mean? CHANDIPURA VIRUS meaning - CHANDIPURA VIRUS definition - CHANDIPURA VIRUS explanation. Source: Wikipedia.org article, adapted under http://ift.tt/yjiNZw license. Chandipura virus (CHPV) is a member of the Rhabdoviridae family that is associated with an encephalitic illness in humans. It was first identified in 1965 after isolation from the blood of two patients from Chandipura village in Maharashtra state, India and has been associated with a number of otherwise unexplained outbreaks of encephalitic illness in central India. The most recent occurred in Andhra Pradesh and Maharashtra in June–August 2003 with 329 children affected and 183 deaths. Further sporadic cases and deaths in children were observed in Gujarat state in 2004. Chandipura virus has been isolated from sandflies in India and West Africa and is probably spread through its bite. The presence of the virus in Africa indicates a wide distribution although no human cases have been observed outside India. The significance of Chandipura virus as a human pathogen is unresolved due to doubts over its role in the 2003 and 2004 outbreaks. Chandipura virus is an enveloped RNA virus with an approximate genome length of ~11 kb. Viral genome codes for five polypeptides, namely, Nucleocapsid protein N, Phosphoprotein P, Matrix protein M, Glycoprotein G and Large protein L in five monocistronic mRNAs. N protein encapsidates genome RNA into a nuclease resistant form to protect in from cellular RNAse function. L and P protein together forms viral RNA dependent RNA polymerase; where catalytic functions for RNA polymerization, Capping and Poly-A polymerase resides within the L protein and P acts as a transcriptional activator. Matrix protein glues the encapsidated genome RNA, also known as nucleocapsid, with the outer membrane envelop. G protein spikes out of the membrane and acts as a major antigenic determinant. Viral life cycle is cytosolic. During transcription, viral polymerase synthesizes five discrete mRNAs and obeys to stop signals that are present at the gene boundaries. Accumulation of adequate amounts of viral proteins within infected cells through viral transcription and subsequent translation potentiate the onset of viral replicative cycle. In this phase, same L protein acts as a replicase and ignore the gene junctions to generate a polycistronic anti-genomic analogue that acts as a template for further rounds of replication to generate many more copies of the genome RNA. This progeny genome RNA upon packaging by viral proteins bud out as mature virus particles. The precise mechanism underlying the switch in polymerase function during viral replication remains unknown. An outbreak in Gujarat in Kheda District, Vadodara District, and Panchmahal District had killed 17 people in 2010. Sandfly bites are blamed as they inhabit cracks in walls or parts of homes made of sand or mud.

[tfgadgets]

Chandipura virus spreading its wings: Claims 32 lives, why children are most vulnerable? |

Gujarat on Sunday reported 13 fresh suspected Chandipura virus cases and five fatalities, the state health department said. With the latest additions, the tally of the confirmed and suspected infections in the state has gone up to 84 so far, while the death toll climbed to 32. Chandipura virus has a fatality of 56-75% It is to be noted that in 2003-2004 similar outbreaks in Central India…