#B-12 deficiency treatment

[covid-safer-hotties]

Global Emergency Compounded by the AIDS-like Features of SARS-CoV-2 Infection - Published Sept 1, 2024

Over a million people in the US are being infected with severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) every day.

Originally named after the acute respiratory syndrome it can cause as a consequence of blood vessel damage in the lungs, SARS-CoV-2 is actually primarily a blood vessel virus that spreads through the airways. It causes a complex multisystem disease (1). It is airborne (2). It can persist in the body, and is detectable in body and brain tissue even at autopsy of “recovered” patients (3).

Each infection ages the body, causes damage to the blood vessels and the immune system, and affects organs including the heart, lungs, liver, kidneys, bones, etc. (4, 5, 6)

Each infection ages the brain. Specifically, it reduces gray matter and cognitive ability (7), and potentially IQ score (8). It increases the risk of psychiatric disorders (9). SARS-CoV-2 has also been identified as contributing to accelerated dementia (10).

The potential post-acute phase impacts of SARS-CoV-2 include long COVID, some manifestations of which are chronic conditions that can last a lifetime, including heart disease, diabetes, myalgic encephalomyelitis and dysautonomia (11).

The Economist has estimated excess deaths from the beginning of the Pandemic through May 2024 at up to 35 million people worldwide. (12)

In Addition, Many Scientists Are Now Issuing Warnings… SARS-CoV-2 triggers a new airborne form of Acquired Immune Deficiency Syndrome (13, 14, 15) (some are proposing specific terms such as “CoV-AIDS”).

This is not AIDS as we know it from human immunodeficiency virus (HIV) infection, it is a new type of acquired immunodeficiency syndrome with different deleterious effects on immune function (16, 17, 18, 19, 20, 21), but both resulting in increased vulnerability to infections (22). Immune system deficiency and other COVID properties also suggest a potential link to greater risk of cancers (23, 24, 25, 26, 27).

The “original” AIDS caused by HIV takes up to around 10 to 15 years to make its presence felt, with the initial infection usually barely noticed and often resembling the common cold or a flu-like disease until its damage manifests itself leading to death in the absence of treatments (28, 29).

With SARS-CoV-2, immunodeficiency develops in the weeks and months following infection. It involves reduction and functional exhaustion of T Cells (30), enhanced inhibition of MHC-I expression (31), downregulating CD19 expression in B cells (32) and other evidence of immune dysregulation (33, 34). In one study, the dysregulation persisted for 8 months following initial mild-to-moderate SARS-CoV-2 infection, the length of the study (35). There is no “cure” for any of the damage caused by SARS-CoV-2 including immune dysregulation.

Did You Know? Repeated infections are leading to prolonged immune dysregulation, and increase the risk of progressive disability and death.

Long COVID is a multisystem disease with debilitating symptoms, which has had a profound impact on society and the global economy. In the USA, economists have estimated that long COVID will incur cumulative future costs of more than US$4 trillion (36, 37).

The worldwide devastating economic consequences of this mass disabling event have been measured in terms of total work hours and GDP lost around the world (38).

It theoretically only takes a single viral particle to initiate an infection, and most infections are initiated by very few viral particles (39).

Despite current popular belief, the immune system is NOT a muscle, and does NOT benefit from being repeatedly challenged with disease-causing microbes. In fact, its finite resources are depleted with each new infection.

Herd immunity is unattainable for a rapidly mutating, immune-disrupting virus, and there is no basis to believe that a vascular infection will evolve into the common cold. Continuing to ignore SARS-CoV-2 will not make it go away. Depriving the virus of publicity does not deprive it of its continuing lethal effects.

SARS-CoV-2 is continuing to evolve and mutate – it is not running out of evolutionary space. It is not a cold or the flu, but primarily a blood vessel disease. It is damaging society as we know it.

How many repeated infections can we expect young people to endure and survive? Even if they get only 1 infection each year, that’s 10 infections in 10 school years. This is not compatible with health and a long life. Repeated infections can lead to long COVID and shortened lifespans.

How Do We Protect Ourselves, How Do We Protect Our Children, When Government Public Health Advice Has Failed?

By reducing transmission so that R0 remains less than one (meaning that each person infects less than one other), we can suppress and gradually eliminate the virus, targeting a safer return to pre-2020 normal.

Handwashing is helpful, but it is not the main way to stop the spread of this airborne virus.

Respirators can block 95% or more of virus particles through electrostatic action, and are therefore highly effective at reducing infection even if only one person in a conversation is wearing them. They are far more effective if all people are wearing them (40).

Transmission can be reduced with HEPA filtration and ventilation of indoor air.

The virus spreads more quickly in indoor settings, but also spreads outdoors.

For medical facilities, it is essential to clean the air with ventilation and filtration and require universal high-quality masking (with N-95/ FFP3 respirators or better) to protect medical staff and patients.

For workplaces, clean air will reduce transmission; and encouraging employees to test and stay home when infectious is essential. High-quality masking should be encouraged in the case of symptoms, a sick person at home, or any other suspicion that one could be carrying the virus. Remote work should be normalized and encouraged wherever possible.

For entertainment venues, events should be held outdoors when possible; and if indoors, clean air is key to protecting audiences. Audiences should also be encouraged to wear respirators to avoid getting infected and infecting others. Digital streaming options should always be offered.

For restaurants, an emphasis on outdoor dining will substantially reduce transmission. Patio service should be encouraged, and indoor dining areas should be well-ventilated with a high level of air-exchanges. Home or curbside delivery offers a safer alternative.

For schools, clean air will reduce transmission; encouraging students to test and stay home when infectious is essential to preserving their health. Masking or remote learning should be initiated whenever a case is detected or the incidence in the general population sharply increases. A permanent hybrid model / digital option can accommodate children with disabilities or those who simply do better learning from home.

Teachers and medical professionals may prefer to use transparent masks, or to wear HEPA-filtered headgear equipment that may be more universally tolerated/accepted.

To track our progress, we need sustained wastewater and population-level testing.

With just 60-70 percent of people taking mitigation measures such as masking, testing and isolating when infected, we can dramatically reduce forward transmission of the virus.

Even with very imperfect measures, as long as one infected person does not infect more than one person on average, the virus will eventually die out. The fewer people each person infects on average, the faster it will happen.

We still have a window of opportunity. Protecting ourselves and our families is in fact protecting the economy and the continued orderly functioning of our society.

[normal-with-adhd-is-a-joke]

things that people who are stop recommending to CFS/ME/SEID/long COVID with PEM and CF (called "PEM w/ CF" henceforth) patients immediately:

Exercise. This includes yoga, pilates, aquatherapy, and other "gentle" exercises. If it works against gravity or another resistance, it's not good for treating PEM w/ CF. The deconditioning theory was debunked years ago, so don't bring that shit here.

B-12. It's important to get tested for a B-12 deficiency as the symptoms can be similar to PEM w/ CF, but once it's ruled out added B-12 can have side effects. The main and most studied one is insomnia, but anecdotal reports (including my own) also often mention racing heart rate and jitters. Since these side effects use up energy, it's better for people with PEM w/ CF to err on the side of caution and avoid excess B-12 intake. Also it's pretty much the first thing anyone suggests so unless someone is newly ill they've likely already tried it and are sick of hearing about it.

Caffeine and other stimulants. While these can make you feel energized temporarily, it doesn't actually increase the amount of energy in your body. Assuming we're running on the theory of PEM w/ CF being a deficiency of ATP caused by mitochondrial issues, fatigue isn't a state of mind. It's our bodies telling us we're running out of fuel to keep them going. Also many of us have a co-morbid tachycardia condition and a flair up of that condition can cause a flair up of fatigue.

Medication and other treatments designed for mental illnesses. While having a chronic illness can cause mental illness, especially if you live in an ableist country with failed disability aid services, mental illness does not cause PEM w/ CF. Treatment for mental illness won't actually treat the symptoms of PEM w/ CF.

Alternative medicine. Many alternative medicine treatments are actively dangerous and the idea that there's "no harm in trying" because "it's natural anyway" is false. Stop recommending ozone therapy (potentially deadly and not useful in concentrations not strong enough to kill you), stop recommended chiropractors (can result in a stroke), stop recommending essential oils (no approved medical use beyond basic relaxation and concentrated nature can make them dangerous), you get the picture. Alternative medicine preys on desperate suffering people to sell them ineffective, potentially dangerous "treatments", don't do their advertising for them.

PEM w/ CF patients feel free to add on treatments that are commonly recommended but unscientific/uneffective, others be respectful and don't derail.

[bear-do-well]

Listening to BiB is like:

*song starts playing*

"oh this is a really good one!"

Autism, also called autism spectrum disorder[a] (ASD) or autism spectrum condition (ASC),[11] is a neurodevelopmental disorder characterized by symptoms of deficient reciprocal social communication and the presence of restricted, repetitive, and inflexible patterns of behavior that are impairing in multiple contexts and excessive or atypical to be developmentally and socioculturally inappropriate.[12][13] Other common signs include difficulty with social interaction, verbal and nonverbal communication, along with perseverative interests, stereotypic body movements, rigid routines, and hyper- or hypo-reactivity to sensory input. Autism is clinically regarded as a spectrum disorder, meaning that it can manifest very differently in each person. For example, some are nonspeaking, while others have proficient spoken language. Because of this, there is wide variation in the support needs of people across the autism spectrum.

Psychiatry has traditionally classified autism as a mental disorder, but the autism rights movement (and an increasing number of researchers) see autistic people as part of humanity's natural neurodiversity.[14][15] From this point of view, autistic people may also be diagnosed with a disability of some sort, but that disability may be rooted in the systemic structures of a society rather than in the person;[16] thus, proponents argue that autistic people should be accommodated rather than cured.[17] The neurodiversity perspective has led to significant controversy among those who are autistic and advocates, practitioners, and charities.[18][19]

There are many theories about the causes of autism; it is highly heritable and mainly genetic, but many genes are involved, and environmental factors may also be relevant.[20] The syndrome frequently co-occurs with attention deficit hyperactivity disorder, epilepsy and intellectual disability, and research indicates that autistic people have significantly higher rates of LGBTQ+ identities and feelings than the general population.[21][22][23] Disagreements persist about what should be included as part of the diagnosis, whether there are meaningful subtypes or stages of autism,[24] and the significance of autism-associated traits in the wider population.[25][26] The combination of broader criteria, increased awareness, and the potential increase of actual prevalence, has led to considerably increased estimates of autism prevalence since the 1990s.[27][28] The World Health Organization estimates about 1 in 100 children had autism between 2012 and 2021, as that was the average estimate in studies during that period, with a trend of increasing prevalence over time.[b][9][10] Boys are also significantly far more frequently diagnosed than girls.[29] The increasing prevalence has reinforced the myth perpetuated by anti-vaccine activists that autism is caused by vaccines.[30]

There is no cure for autism. Although early intervention services based on applied behavior analysis (ABA) can help children gain self-care, normative social, and language skills,[31][32][33][34] independent living is unlikely with more severe forms of the condition. Some in the autism rights movement consider ABA therapy unethical and unhelpful due to a perception that it emphasizes normalization instead of acceptance and its potential for causing harms.[35][36][37] ABA's prioritization of compliance and behavioral modification over a person's needs can lead to harmful consequences, including prompt dependency, loss of intrinsic motivation, and even psychological trauma. Curtailing self-soothing behaviors is potentially classifiable as a form of abuse.[38] Speech and occupational therapy, as well as augmentative and alternative modes of communication, are effective adjunctive therapies. Pharmacological treatments may also be useful; the atypical antipsychotics risperidone and aripiprazole are empirically validated for alleviating comorbid irritability, though they tend to be associated with sedation and weight gain.[39]

[riyasharmask]

What are 7 ways to boost your immune system?

Immune system is the body’s defence mechanism that helps in fighting with different life threatening microscopic organisms, chronic diseases and disorders.

Duties and responsibilities towards family members and society, financial pressure and stress do not let us think and act in a positive way and stay healthy.

Such unavoidable circumstances are taking control of our life. We are inclined towards eating fast and processed food items, smoking nicotine and different types of prohibited drugs and drinking alcohol.

As a result, we do find ourselves trapped in different diseases in different parts of the body.

Let’s understand the signs of weak immune system and these are:

a)  Constantly suffering from cough and cold.

b)  High level of stress

c)  Excessive stomach problem

d) Wounds not easily healing.

e)   Intense infections.

f)  Easily getting tired.

Instead of spending huge amounts of money on medicines and treatment of the immunocompromised diseases like cancer, diabetes, hepatitis and other intestinal disorders, it is recommended to rely on Ayurveda. In fact, Ayurveda happens to be rewarding for your health. To achieve strong immune system, you need to maintain:

a)  Healthy liver function.

b)  Good digestive ability.

c)  Good hormonal and ojas balance.

d) Strong metabolism

Ayurveda would suggest you to go for simple steps for boosting immunity in the body

a)   Maintaining a proper diet: It is the foremost thing to maintain healthy immune system. Depending on the deficiency of kapha, vat and pitta doshas, you must actually select and eat the right food items. Most important thing is to boost and protect ojas and that is by consuming different types of nuts, raisins, dates, saffron and ghee. Adding garlic in your regular diet will help in removing toxins from the body and help you to fight cough and cold.

b)   Adequate sleep: Depending on the health condition , there is a need for proper balanced sleep. If you are suffering from kapha dosha then you must have 6 to 7 hours of sleep. Person suffering from vata dosha would require 8 hours of sleep. It will help in recovering from any type of joint pain. Person undergoing the problem of pitta dosha would have moderate sleep, not high as a vata dosha patient nor little as kapha dosha..As per the studies of researchers, adequate amount of sleep reduces the development of cancer.

c)    Waking up early:  Coming in contact with the rising sun boosts Vitamin D for the body. Further, it sharpens your memory and keeps your body and mind active.

d) Exercise and yoga: Regular exercise and yoga in the morning hours before taking bath and breakfast will help in bringing relief from the toxins from the body. It will boost blood circulation and good gut health. Dancing, swimming, running, doing push ups and squatting are some exercises that one can adopt and practice on a daily basis. One can deal with cough and cold and nerve related disorders with the help of pranayama or simple breathing exercise.

e)    Reduce stress:  To wipe out the stress level from the body, you can engage in the activities that appeal to you or you find them interesting. You can travel to your favourite destination where you can get the opportunity to connect with nature. Meditation is another way of fighting stress. Ayurveda suggests to go for herbal steam therapy to reduce the stress hormone, boost blood circulation and nerves of the brain and body. Oil massage on the body and forehead is highly effective in reducing stress.

f)    Manage rising weight:  Weight management is another way to control obesity. To stay healthy for a long period of time, one should not be too obese or too thin. Or else, you will suffer from cardiovascular problems, high cholesterol and high blood pressure. Too much thinness will lead to deficiency of iron, vitamins and other necessary nutrients.

g)   Staying hydrated: Drinking 8 to 12 glasses of water will cleanse the body from the toxins, boost healthy bowel movement and control dehydration, diarrhea and intestinal disorders

Above mentioned ways strengthen your immune system. As per the experts’ opinion, your strong bonding with nature will help to gain key to healthy life.

[prolife-home-care]

Top 10 Best Places to Get Blood Work Done in NYC (2024 Guide)

Getting your blood work done regularly is an important way to keep track of your overall health. Routinely going in to get your blood tested allows you to see how your health is changing over time and that can empower you to make good decisions about which additional diagnostic tests you may need and which treatments to pursue.

Ideally, you should get your blood checked at least once every year, but you may choose to have it done more often than that depending on your health status and your doctor’s recommendations.

What is checked in routine blood work?

Routine blood work often includes the following tests:

●       A complete blood count

●       Thyroid panel

●       Blood chemistry panel (also known as the Basic Metabolic panel)

●       Nutrient tests for B vitamin and iron levels

●       Enzyme markers that may indicate that you’re at risk for certain diseases like cancer, stroke, celiac disease, or liver cirrhosis

●       STD/Sexually Transmitted Diseases tests (these are especially important if you have multiple sexual partners or a new partner recently)

What should you do before a blood test?

Before a blood test, it’s best to fast for at least 8 to 12 hours. If you don’t fast before getting routine blood work done, everything that you eat and drink can disrupt the results and cause elevated levels of certain blood elements and reduced levels of others. By not eating for 8 to 12 hours before your blood test, you can ensure that your blood test results are free from confounding variables.

Fasting is especially important if you’re having any of the following blood tests done:

●      Glucose tests

●      Cholesterol tests

●      Liver function tests

●      Basic metabolic panel testing

●      Kidney function tests

●      Blood sugar tests  

Expert Opinion on the Importance of Regular Blood Work

"As the Director of Patient Services at Prolife Home Care Agency, I’ve seen firsthand the immense value of regular blood work in maintaining health and preventing serious conditions. One case that stands out involved an elderly patient who had been feeling fatigued but attributed it to aging. After routine blood tests, we discovered she had severe anemia and early signs of kidney dysfunction, which could have easily gone unnoticed. Thanks to these early findings, we were able to adjust her treatment plan, improving her quality of life and preventing further complications. Regular blood tests provide invaluable insights into your health, helping to detect issues like nutrient deficiencies, infections, and even early-stage diseases. I always advise my patients that proactive monitoring through blood work is one of the most effective ways to stay on top of their health and catch potential problems early, often before symptoms arise."

Anna Klyauzova, Director of Patient Services at Prolife Home Care Agency

The Ten Best Blood Labs in NY

1.Elitra Health (5.0 Stars)

Elitra Health is a Mount-Sinai-affiliated medical facility and a leader in preventive healthcare and longevity. The facility was established in 2016.

Patients can receive any of the following diagnostic procedures during their visit:

●       Intensive testing and evaluation

●       Detailed medical history

●       Complete physical exam

●       Complete cardio-pulmonary exam

●       Comprehensive blood profile and lab analysis

●       Comprehensive review of the results

●       Nutritional and lifestyle analysis

●       Imaging services

●       Fitness exam and analysis

●       Women’s Health Exams

●       Advanced testing options

●       Physician consultation with healthcare recommendations to empower patients to achieve greater control over their healthcare options

●       Early detection of Alzheimer’s Disease, cancer, neurological functioning, cardiovascular functioning, and more

The Elitra Health facility is located in a luxurious space appropriate for offering the world’s finest and most comprehensive medical assessment. The exam goes beyond the common annual physical workup, offering such an extensive and thorough evaluation of the patient’s health that at a normal clinic, patients would have to return for 6 different visits on 6 different days. The Elitra Exam, in contrast, is completely on-site, in a beautiful, immaculately clean, spa-like location, that takes only 4 to 6 hours.

Most patients rave about the customer service, the knowledgeable physicians, and detailed exam reports that are available at this facility, but some patients have had some scheduling problems that were eventually resolved by the front desk staff. Call to confirm your appointment in advance to avoid these issues.

Elitra Health is located just two blocks from the Park Place metro station. There is also on-street parking near the facility.

The cost of a full workup for the average patient is approximately $10,000.  

2.Patient Service Center (5.0 Stars)

Patients report that the Patient Service Center is very conveniently located and they offer efficient service and care, getting patients in and out of the facility as quickly as possible. Blood draws are quick and painless.

There are a number of Patient Service Centers throughout the city and they vary in terms of their accessibility via public transportation. But because there are so many different locations to choose from, most patients can find a location that suits them.

Testing at Patient Service Centers are available to assess the following:

●       4KScore Prostate Exams

●       Allergy testing

●       Chronic fatigue testing

●       Gastric distress exams

●       COVID-19 testing

●       Diabetes testing

●       Heart disease testing

●       Hepatitis testing

●       Hereditary cancer testing

●       Sexual health exams

●       Zika virus exams

●       Tuberculosis exams

Customers mostly report that the service they receive at these facilities is fast, efficient, and the customer service is excellent although each facility throughout the city has a different customer service reputation. Some locations report long wait times and poor experiences with the front desk staff. Locations also vary in terms of cleanliness and general maintenance.

In some cases, insurance will cover the cost of Patient Service Center exams. Financial assistance is available for some eligible patients who elect not to use their insurance. Tests are offered at reasonable prices so that average patients who don’t have health insurance can afford them.

3.RapidX Mobile Diagnostic Services (5.0 Stars)

RapidX has been providing mobile diagnostic services to medical facilities, home-bound patients, and nursing home residents since 2010. Customers say that the service provided by this company is fast and reliable.

RapidX is a mobile testing and diagnostic service so patients who are not able to go to a facility can order tests from their home. They are open 24 hours offering:

●       Ultrasound imaging

●       Diagnostic Imaging

●       Portable x-rays

●       Bloodwork

Both patients and doctors consistently give this company 5-star ratings with excellent reviews because they offer good customer service and front-door service at affordable prices. The cost of their services are rated as two dollar signs on Facebook.

4.SimonMed Imaging – Carnegie Hill (5.0 Stars)

SimonMed offers a comprehensive lineup of radiology and diagnostic services to patients in New York City and throughout the nation. SimonMed Imaging offers an elite clinical experience to patients and ultra-high quality care that includes the following service options:

●       CT Scans

●       Pet/CT Scans

●       MRI

●       Mammograms

●       Bone Density Testing

●       Ultrasounds

●       Nuclear Medicine

●       Fluoroscopy

●       Interventional Radiology

●       X-Rays

Patients report that the customer service at the Carnegie Hill location is excellent. It is easy to access this facility from the 77 Street subway station which is only a half a block away. There is on-street parking available outside. Customers say that the facility is clean and that the staff makes a concerted effort to make sure patients are comfortable during the procedures. Wait times are reasonable.

Pre-visit estimates are provided to patients based on their insurance provider. For individuals without insurance, a cash price is available. Out-of-pocket costs are typically much less through SimonMed than they would be through a hospital.  

5.Raisler Testing Center / Northwell Health Labs (4.9 Stars)  

Northwell Health Labs provides convenient blood work and clinical testing for patients throughout New York and Long Island. Customers report that the staff at these facilities are extremely friendly and professional and that lab results are accurate. Wait times are extremely reasonable and the facilities are clean and well-organized.

Northwell Health Labs offers numerous locations throughout the city so patients can drive or take public transportation to a location that’s most convenient for them.

Northwell Health Labs offers a variety of different assessments including:

●       COVID-19 testing

●       Blood tests

●       Urine tests

●       Bodily fluid tests

●       Tissue tests

Fees for laboratory tests and blood work is reasonable and all major insurances are accepted. Patients can all pay in cash or with check or credit card. The exact cost of each procedure varies from patient-to-patient depending on whether they have insurance and the type of insurance they carry. If you have questions about the cost of treatment, contact the Northwell Health Labs offices directly for more exact information.

6.CityMD Urgent Care (4.2 Stars)

CityMD is noted by customers as an excellent blood test option for minor concerns that are time-sensitive, but not particularly serious. They can do x-rays, provide vaccinations, and basic physical exams but they don’t have a lot of sophisticated equipment. They offer basic lab tests with quick results in a clean facility with excellent customer service.

This is an UrgentCare facility with doctors on staff to perform very basic services. The front office staff is reportedly very organized and friendly. The cost of services depends on the type of insurance the patient carriers and the amount of coverage offered for each specific test.

CityMD offers a range of tests including:

●   COVID – 19 testing

●   Blood draws

●   HIV testing

●   Sexually Transmitted Disease (STD) testing

●   Influenza testing

●   Mononucleosis testing

●   Strep tests

●   INR tests

●   Pregnancy testing

●   EKGs

●   Urinanalysis

There are multiple CityMD locations throughout New York. Some facilities are located near parking while others are conveniently located near public transportation such as buses or trains. Choose a location that best meets your needs.

7.Lenco Diagnostic Laboratories (4.1 Stars)  

Lenco labs works directly with customers as well as with healthcare facilities. They provide the following services:

●   COVID-19 antibody testing

●   COVID-19 PCR testing

●   Allergy testing

●   Bacteriology testing

●   Chemistry

●   Cytopathology

●   Endocrinology

●   Hematology

●   Histopathology

●   Immunology

●   Parasite testing

●   Toxicology

●   Urine tests

●   Tumor markers

Customers give Lenco excellent reviews for their precision, accuracy, safety protocols, and customer service. Representatives at Lenco reportedly work tirelessly on behalf of clients. They offer a phone app that’s easy to use and easy to read. Turnaround time is extremely fast.

Lenco offices are clean and well-maintained. Customers report that wait times are minimal. On street parking is available outside the facility. The Kings Highway metro station is located about 10 blocks away.

The cost of lab tests at Lenco Diagnostics is dependent on the following factors:

●   Your insurance

●   Your age – for ages 65 years and older, Medicare will not pay for certain tests

●   Your healthcare provider’s agreement with Lenco

Contact Lenco Diagnostics Laboratory directly for more detailed pricing information.  

8.   Quest Diagnostics (3.9 Stars)

Quest Diagnostics offers the following testing services and medical procedures:

●       Bloodwork

○       Blood type exam ($39)

○       Complete blood count ($29)

●       General health exams

○       Basic Health Profile ($149)

●       Women’s health exams

○       Pregnancy Test ($39)

●       Men’s health exams ($199)

●       Digestive health

○       Celiac / Gluten Intolerance exam ($119)

○       Seafood Allergy Panel ($149)

●       Heart health

○       Cholesterol panel ($59)

●       COVID-19 exams

○       COVID-19 Active Infection test ($119)

○       COVID-19 Antibody Test ($119)

●       Infectious disease tests

○       Chickenpox / Shingles exam ($59)

○       Lyme Disease Test ($89)

●       Sexually Transmitted Disease (STD) tests ($199)

●       Metabolic Exams

○       Comprehensive Metabolic Exam ($49)

○       Diabetes Management Exam ($69)

○       Diabetes Risk Exam ($99)

There are a variety of Quest Diagnostics facilities throughout New York City and each one receives different reviews in terms of customer service, accessibility of location, and overall ratings. This facility offers transparency in terms of pricing which is appreciated by customers, though some customers report that there are long wait times and special challenges that have presented themselves due to the COVID-19 pandemic.

Customers report that the facilities are generally clean and the staff at the various locations in the city are friendly. Most customers can find a location that’s accessible to them either via public transportation or private vehicle.

Customers report that wait times are extremely reasonable at Labcorp and the staff is friendly and helpful. A number of patients report that they get into their appointments early, but a few patients reported wait times of 30 minutes or longer. Some patients have experienced miscommunications with the front office staff. Customer service is variable according to reviews, but the lab technicians are rated highly.

Some customers report that these facilities are not as clean as some of the other facilities on this list and the check-in process is sometimes disorganized.

Labcorp facilities are available throughout the city. Patients can choose the most conveniently located facility near public transportation or on-site parking lots that meets their needs.

Labcorp offers tests in the following categories:

●       General health

○       Allergy Tests

○       Blood tests

●       Women’s health

●       Men’s health

●       Digestive health

○       Amino Acid Tests

●       Heart health

●       Infectious disease

○       Parasite testing

○       Virology

●       Sexually Transmitted Disease (STD) testing

●       Genetic testing

●       Paternity Testing

The cost of tests at Labcorp vary depending on whether or not the patient has insurance or not and what type of insurance the patient has. For detailed information about Labcorp prices that are specific for your situation, you can contact them directly.

10. Enzo Clinical Labs (2.8 Stars)

Enzo Clinical Labs has several locations throughout New York so patients can choose the facility that’s most accessible to them. Patients report longer wait times at these facilities than at other laboratories in the city. The clinics are reportedly tidy, and the front staff is reasonably friendly but some of the technicians aren’t well-trained.

Enzo does not currently allow patients to self-order tests, but due to recently enacted legislation, the patients will be able to self-order a limited number of tests in the future. The cost of tests will depend on the patient’s insurance carrier, if they have one and which procedures are covered. The cost of Enzo tests varies depending on the type of insurance the patient carries.

Enzo offers a wide-array of different tests including:

●       General health screenings

●       Women’s health tests

●       Pregnancy testing

●       Men’s health tests

●       Digestive health tests

●       Nutritional deficiency testing

●       Heart health

●       Infectious disease

●       Sexually Transmitted Disease (STD) testing

●       Genetic testing

●       Drug testing

●       Paternity Testing How to Choose the Right Lab

Choosing the right lab comes down to several factors:

Convenience: Consider the location and whether the lab offers walk-ins or requires appointments.

Pricing: If you don't have insurance, check for cash pricing or payment plans.

Services: If you need specialized tests, ensure the lab offers them.

Insurance Coverage: Verify if your insurance is accepted and if any pre-approvals are needed.

Conclusion

With a variety of top-tier labs to choose from in New York City, you can find the right place to get your blood work done based on your needs, location, and budget. Whether you need a quick walk-in test or a more comprehensive examination, the options listed here provide reliable and efficient services across the five boroughs.  

Frequently Asked Questions (FAQs)

1. How often should I get blood work done?

It is generally recommended to get routine blood work done at least once a year. However, depending on your health condition or any chronic illnesses, your doctor may recommend more frequent testing to monitor specific markers or conditions.

2. Do I need to fast before getting blood work?

Yes, fasting is often required before certain tests, such as cholesterol or glucose tests, to ensure accurate results. Typically, you should avoid food and drinks (except water) for 8-12 hours prior to your blood test. However, not all blood tests require fasting, so it’s important to check with your healthcare provider.

3. What can blood tests reveal about my health?

Blood tests can provide a wealth of information, including the status of your organs (kidney, liver), nutritional deficiencies (like iron or vitamin B12), hormone levels (thyroid), and cholesterol levels. They can also detect infections, monitor chronic conditions, and assess your overall risk for diseases like diabetes and heart disease.

4. Can I get blood work done without insurance?

Yes, many labs in NYC offer cash payment options for those without insurance. Prices for tests can vary, but some labs provide affordable rates or financial assistance programs to ensure accessibility.

5. How long does it take to get blood test results?

Turnaround times for blood test results can vary depending on the type of test and the lab. For routine blood work, results are often available within 1-3 days. Some specialized tests may take longer, but most labs offer online portals where you can access your results as soon as they’re ready.

6. What should I bring to my blood test appointment?

You should bring a valid ID, your insurance card (if applicable), and the test order from your doctor. If you’re paying out-of-pocket, inquire about payment options before your appointment. Some labs also recommend wearing loose-fitting clothing to make the blood draw process easier.

7. Can I do a blood test at home?

Yes, some labs, like RapidX Mobile Diagnostic Services, offer home testing for those who cannot visit a facility. Additionally, there are home test kits available for specific blood tests, but it’s important to ensure these tests are appropriate for your needs and validated by healthcare providers.

[chicagopaincontrol]

Small Fiber Neuropathy Explained

It is safe to say that we have all experienced some sort of random pain from doing a mundane activity. Perhaps it was experiencing a sharp pain from grabbing a glass of water late at night or a strange tingling sensation from organizing around the house, making a meal, or taking out the trash. When someone experiences pain like this, it could be for a more serious reason than we may expect. 

Small fiber neuropathy (SFN) is a condition that affects small nerve fibers in the skin and possibly is the reason for all those random pains you’ve been having. It occurs when the small fibers of the peripheral nervous system, which are located outside the brain and spinal cord, are damaged. SFN can come about from many different sources such as diabetes, chemotherapy, HIV/AIDS treatment and typically begins in the feet and works its way up affecting other parts of the body such as legs, hands, arms, and torso.

This condition may sound concerning but it is not life-threatening (although it is painful) and rarely ever needs surgery. 

Symptoms vary depending on a number of factors, such as underlying conditions, but they can be debilitating. The following are just a few lifestyle changes that can help manage symptoms. 

Lifestyle Changes 

Walk the Walk

It’s no surprise that daily exercise is important to a healthy lifestyle. This is especially true for those who have small fiber neuropathy. Exercising is good for the lungs and helps build muscle. Walking helps improve blood flow in the legs and feet, strengthens and tones your muscles. Daily movement and walking is a great way to mitigate further tingling, burning, or numbness that may develop if you have neuropathy due to diabetes or other conditions. 

Super Supplements 

Life gets busy and it’s easy to forget about the little things, like taking vitamins and getting the nutrients we need every day. However, vitamin deficiency is a common contributing factor to neuropathy suffering. When we aren’t consuming enough vitamins & nutrients and aren’t absorbing them efficiently, our bodies lack the foundational nutrients that it needs to perform various tasks, such as maintaining the nervous system, healing the body, and working effectively. 

To combat the lack of vitamins and nutrients your body receives on a daily basis, the following supplements may help to support your body against neuropathic pain:

Vitamin B-12 – The body can absorb this vitamin into the bloodstream to improve reflexes, lessen pain, pricking, or tingling sensations, and provide overall nerve health. This vitamin also benefits the circulatory and immune systems. 

Vitamin D – Many patients with neuropathy have vitamin D deficiencies if they are diabetic or suffering from peripheral neuropathy. Vitamin D supplements may help improve the symptoms of those afflicted with diabetic neuropathy and help remedy the nutritional deficit in their diet. 

Omega-3 Fatty Acids – For patients with neuropathy, working this supplement into a daily regimen can help as an anti-inflammatory and decrease burning and numbness associated with pain. 

Make sure to consult with your doctor before adding any vitamins or supplements to your diet.

Happy Feet

SFN is most commonly seen in the feet, and affects the lower extremities of the body, especially tingling, loss of balance when walking, or burning sensations in the feet. Taking good care of your feet as someone who deals with neuropathy is the best way to prevent further nerve damage and muscle weakness from developing. 

Clean and manicure your feet every day – Keep your toenails short and manicured to avoid ingrown nails. Constantly be on the lookout for swelling, redness, or signs of tear and if you find anything unusual on your toes or feet, make sure to report back to your physician or nurse. Foot moisturizer is also recommended to care for the skin on your feet. 

Wear the right footwear – Make sure that you are not going barefoot outside, or walking barefoot over hard surfaces. Support your heel, keep your feet inappropriate shoes. Remember to wear socks, but make sure they are on correctly. Ill-fitted socks can be bothersome to your circulation or trigger a tingling sensation in the feet. Consider foot tents to keep your feet separated from your comforter when sleeping at night, that way you trigger any sensory issues due to small fiber neuropathy. 

Serious Stuff

SFN can, unfortunately, become more complicated depending on the underlying conditions a patient may have. Due to complications, more involved treatments may be necessary to help with symptoms. There are a number of medications that can help alleviate symptoms. Over-the-counter medication such as nonsteroidal anti-inflammatory drugs (NSAIDs) can help alleviate pain and don’t need to be prescribed by a doctor. For more serious pain, a physician may prescribe more intense treatments such as: 

Antidepressants & Anticonvulsant Medications – These medications reduce neuropathic pain by modulating peripheral nerves, the spinal cord, or the brain. They tend to be the most effective type of medication for this condition. 

Narcotic Agents – Narcotic agents are another option for treatment but can lead to unhealthy dependence and addiction so they are only recommended when other treatments prove ineffective

Mechanical Aids –  Hand and foot braces can assist with relieving pain and physical disability caused by weakness or nerve compression

Surgery – Although uncommon, surgery can become an option depending on the underlying conditions and is normally only considered for pain caused by a single nerve.

Outlook

SFN is a rather complicated condition with lots of varying aspects. Luckily there are a wide array of treatment options whether they be conservative or more involved. Anyone experiencing this condition should seek professional help to create a personalized treatment plan for this condition. Following doctor recommendations and changing daily habits can be crucial to pain relief and can help you get back to the quality of lifestyle you deserve. 

[botanyone]

Sorghum Roots Adapt to Thrive in Low-Phosphorus Soils

Sorghum Roots Adapt to Thrive in Low-Phosphorus Soils https://ift.tt/LSOxPrw Scientists have discovered how sorghum roots adapt to low-phosphorus conditions, potentially paving the way for more resilient crops. Mikwa and colleagues studied nearly 300 sorghum varieties, finding that roots grow longer and thinner when phosphorus is scarce. This allows plants to explore more soil and scavenge limited nutrients efficiently. Understanding these adaptations could help breed crops that thrive with less fertiliser, addressing concerns about dwindling phosphorus supplies and future food security. The study revealed significant adaptations in sorghum root architecture under phosphorus-deficient conditions. Roots grew longer and produced more tips, while becoming thinner to cover more area efficiently. These changes were observed as early as 21 days after germination, with variations among different sorghum varieties. The researchers identified four distinct root system types, suggesting genetic control over these adaptive responses. Researchers grew sorghum seedlings in paper pouches with nutrient solutions under controlled greenhouse conditions. They used two treatments: optimal phosphorus and phosphorus-deficient. Root system images were captured at 21 and 42 days after germination using a high-resolution camera. Advanced software, RhizoVision Explorer, analysed these images to extract detailed root architecture traits. The team also conducted genetic analysis using DarTSeq technology to identify DNA markers associated with root responses to phosphorus availability. Phosphorus is crucial for crop growth, but global supplies are dwindling, threatening future food security. Sorghum, a vital cereal crop known for its climate resilience, is increasingly important in this context. Understanding how sorghum roots adapt to low phosphorus could lead to breeding more efficient varieties that require less fertiliser. Mikwa, E.O., Wittkop, B., Windpassinger, S.M., Weber, S.E., Ehrhardt, D. and Snowdon, R.J., 2024. Early exposure to phosphorus starvation induces genetically determined responses in Sorghum bicolor roots. Theoretical and Applied Genetics, 137(220). https://doi.org/10.1007/s00122-024-04728-4 (OA) Cross-posted to Bluesky, Mastodon & Threads. The post Sorghum Roots Adapt to Thrive in Low-Phosphorus Soils appeared first on Botany One. via Botany One https://botany.one/ September 20, 2024 at 12:30PM

[unzipcraft]

Looking for what is the best fertilizer for mango trees?

Guide to the Best Fertilizer for Mango Trees

Mango trees are so lush and many of them produce an abundance of fruits, they make wonderful additions to any garden. While this is still a critical part, choosing the best plant nutrition for mangoes can be the difference between growing an abundant quality fruit on your well-established mango tree or not. This article will go in-depth on what makes a good fertilizer for mango trees, looking into the nutrient needs of mangoes as well as different types of fertilizers to use and methods planting advice that can help you achieve not only healthier but more productive sweet fruit.

Requirements of nutrients in Mango Tree

Each growth stage of mango trees requires different nutrients. It mostly needs a proper supply of basic nutrients for better growth, flowering and fruiting. The primary nutrients are:

Nitrogen (N): Vital element for optimum leaf and shoot development. This helps promote robust growth and is essential for the vegetative stage.

Phosphorus (P): Essential for root growth and flowering. While this modification certainly benefits the tree in setting and retaining fruit, it is also makes harvesting far cleaner.

Potassium (K), critical for fruit development and plant health in general. It increases resistance to diseases and quality of fruits.

Apart from these major nutrients, mangoes require secondary (Calcium-Ca; Magnesium-Mg), and micronutrients such as Ferrous-Fe, Manganese-Mn,Zinc-Zn,Copper -Cu,Boron-B and Mo. A good, balanced fertilizer will meet these needs and help your tree reverse signs of aging for healthier, more fruitful growth.

What Types of Fertilizer for Mango Trees

Complete Fertilizers: have all three primary nutrients (N-P-K) with a varying ratio. General-purpose fertilizers, like a balanced formula of 10-10-10 or 14-14-14 is most commonly recommended for mango trees that provides an equal proportioned nutrient supply during all stages of growth.

Fertilizantes Especiales Para Mangos: Algunos fertilizantes estan elaborados para manglares con proporciones segun la necesidad del árbol. These may contain more phosphorus to facilitate flowering and fruiting. Look for one with a formulation of 8-12-8 or, if this is not available, then use 6-12-6 as these are the best type to serve well your developing my mango tree.

Organic fertilisers: these would include compost, manure and specially formulated organic blends. Such fertilizers also improve soil structure and fertility for the long-term, as they are slow-release in nature. Long term soil health and sustainability organic fertilizers

Time-release Fertilizers: These fertilizers release nutrients slowly over a long duration and are not weeded out often. They are particularly useful for preserving a consistent source of nutrients and reducing the opportunity cost fertilizing.

Liquid Fertilizers: Liquid fertilisers can be poured onto the soil next to plants or applied as a foliar spray. They readily take up nutrients and so can be beneficial during key growth stages or to correct particular deficiencies.

Fertilizing Mango Trees: A Few Applications Tips

When Do You Fertilize Mango Trees? Timing is everything! Apply up to three or four applications per year for fertilizing young trees. A mature tree may only need four treatments. Fertilize the plant only twice in a year and on appropriate times, that is early at spring when they begin to grow new buds or midsummer. Refrain from fertilizing while the tree is dormant or not actively growing.

APPLY: Fertilizer APPLY RATE: Consult manufacturers instructions or follow general guidelines represented on bag for desired amount. Expert Tip: Nitrogen compounds break down fast, and over-fertilizing may create nutrient imbalances in the tree. You'll also want to consider applying fertilizer — divided into multiple applications across the year — using a common guideline for mature mango trees of 1-2 pounds per inch of trunk diameter.

Application: APPLY GRANULAR as top dresser/under the drip line of canopy for granular nutrients. Do not place the fertilizer directly against the trunk because it will result in root burn. After application water the area liberally this will allow for the nutrients to travel into and throughout soil.

Soil Testing: A soil test can give you more information on your soil nutrient levels and pH. This data will better help you customize your fertilization program to correct any individual deficiencies or imbalances (and keep it in check) so that your mango tree can enjoy its best environment.

Mulching–A layer of mulch around the base will hold in soil moisture, moderate temperatures and provide slow added compost to our soils over time. In other words, using mulch can enhance the effects of your fertilization by working to improve soil structure and nutrient access.

Mistakes to Avoid & How They Arise

Too Much of a Good Thing: One significant problem with fertilizer is that too much can lead to imbalances in nutrients and harm the environment. Follow recommendations and stay away from applying more than necessary.

Sure! How to care for a Mango Tree Ignoring Soil Conditions – Mango trees like well-drained sandy loam soils. Make sure the soil drains well and do not water excessively, as it might result in root rot.

Ignoring Micronutrients: As much as N-P-K is on top of the food chain, many micronutrients are part in parcel of mango tree health. For those who suspect any deficiencies, verify to make use of a whole fertilizer that gives all these essential parts.

Inconsistent cultivating: Prolonged and frequent feeding is essential to keep the apple flowers growing well in order for them as a way of bearing more fruit. Outline a time schedule and most importantly commitrences to it(predictions:QoS)

[gastro-delhi]

Stomach Cancer Surgeon in Delhi

Stomach Cancer is one of the malignancies which remain difficult to treat as it spreads fast. So it becomes important that we are aware of it and respond at the earliest to any particular symptoms.

What is stomach Cancer Surgeon in Delhi?

When there is uncontrolled growth of cells in your stomach it is known as stomach cancer.

What are the risks factors for development of stomach Cancer Surgeon in Delhi?

There are certain risk factors which can make one person prone to stomach cancers. But that does not mean that any person having risk factors will develop stomach cancer, similarly also a person without any risk factors can develop cancer.

Smoking and alcohol: these are two major risk factors. Risk of getting cancer increases proportionately to the amount and duration of tobacco or alcohol use

Diet: Non vegetarian diet especially smoked foods increase the risk

Obesity: It is a statistically significant risk factor for the development of stomach cancer

H pylori infection: This bacterial infection of the stomach is known to cause stomach cancers.

Pernicious anemia: Or Vit B 12 deficiency anemia has also been associated with stomach cancers

Stomach Polyps: Risk is higher in people who have small growths from the stomach mucosa called as polyps

Blood group A: These people are also at slightly higher risk

What are the symptoms of stomach cancers?

Indigestion: Indigestion is not uncommon but any symptoms of hyperacidity which is persistent and disturbing should be thoroughly investigated as it may be the first symptom of stomach cancer.

Black stools: Black tarry stools signifies bleeding from the upper GI tract and can occur from cancer of the stomach

Unexplained weight loss or loss of appetite

Blood in vomiting

Feeling of fullness after meals

Weakness

How is stomach cancer diagnosed?

With any of the above symptoms you should visit your gastroenterologist or GI surgeon/Oncologist. They will order certain tests to diagnose the problem.

a. UGI Endoscopy: This involves placing a camera through your mouth into the stomach to look for any abnormal growth and taking the biopsy.

Once the diagnosis is confirmed on biopsy, your surgeon will be ordering one CT scan of the abdomen.

b. CT Scan: This will tell about the extent of the disease and help your surgeon in deciding the Surgery.

How is stomach cancer treated?

Stomach cancer treatment involves

Surgery

Chemotherapy

And sometimes radiation therapy

Surgery remains the mainstay and involves removal of a part or total stomach depending upon the location of the tumor with subsequent reconstruction.

Chemotherapy and radiotherapy are usually given after the surgery but sometimes if the initial disease is bigger and not appropriate for surgery you might be asked to take chemotherapy and/or radiotherapy prior to surgery to make the disease operable.

To schedule an appointment With Dr. Neeraj Goel for Cancer Surgeon in Delhi, please contact: Name: Dr. Neeraj Goel (Cancer Surgeon in Delhi) Address: D-1, Hakikat Rai Rd, Block D, Adarsh Nagar, Delhi, 110033 Phone: +91–9667365169, +91–9599294453 Website: www.gastrodelhi.com

[fshbxnes]

This is also interesting to me bc for one of my assignments rn I’m researching the microbiome changes that ME/CFS has. (Unclear if cause or correlation atm.) TLDR is that ME/CFS patients have shown deficiencies in 12 bacteria, some are known to be producers of enzymes that cells need to function properly. Idea is that if the gut microbiome is traceable it could b treatable, and might lead to a treatment for ME/CFS. And it would (hypothetically!!) largely be diet changes. Which has proven true for me, my symptoms have been much easier to manage now that I’m eating better (and instantly get worse when I struggle). And the research has made me so interested in the broader relationship between gut + brain and the implications that might have on treatment/prognosis of different conditions/diseases.

[mihikavasant]

Recognizing White Gums’ Symptoms and Their Effects on Your Health

White gums can be significant markers of a number of health problems, and early detection and treatment of these problems depend on knowing what causes them. The following list of nine typical causes of white gums and preventative steps to keep your mouth healthy:

Bad Oral Hygiene: When plaque and bacteria accumulate in the mouth, it can cause irritation and discolored gums. Maintaining good oral health requires twice daily brushing, daily flossing, and routine dental visits.

2. Leukoplakia: The second condition is leukoplakia, which manifests as thick, white spots on the gums and other oral tissues. Even while they are not usually harmful, certain cases could be precancerous, particularly if patches develop next to red lesions. Two such reasons are excessive alcohol consumption and tobacco use.

Gingivitis: The first stage of gum disease, gingivitis is brought on by plaque accumulation and manifests as red, swollen, and inflamed gums. It can develop into more serious kinds of gum disease if left untreated.

Canker Sores: White areas at the gum line may result from painful mouth ulcers, commonly referred to as canker sores. These oval or circular sores can be very painful and make it difficult to talk, eat, or drink.

Anemia: White gums could be a sign of anemia, which is a low red blood cell count. Anemia may be caused by iron or vitamin B-12 deficiency, inflammatory conditions, or other illnesses. See a medical professional for an accurate diagnosis and course of treatment.

Thrush: Known medically as oral thrush or candidiasis, this fungal/yeast infection results in elevated, creamy-white patches or ulcers in the mouth. It is particularly prevalent in people on specific drugs or those with weakened immune systems.

Tooth Extraction: Because of surgical damage, gums around a tooth extraction may become pale. After a few days, the gums should revert to their natural color, as this is a transient condition.

Teeth Whitening: Because of the chemicals used during in-office procedures, transient gum discoloration may follow. The gums should revert to their natural color in a matter of hours, as this impact is transient.

Oral Cancer: In rare instances, white gums may be a sign of oral cancer, which can affect the tongue, gums, and roof of the mouth and spread quickly. Frequent dental examinations are essential for early detection because symptoms of oral cancer may not always be apparent.

Advice on Preventing White Gums:

Use fluoride toothpaste to brush teeth twice a day, paying special attention to the gum line.

Use floss every day to get rid of plaque at the gum line and in between teeth.

Make time for routine dental examinations to spot issues early and receive professional cleanings.

Keep up a diet high in nutrients and high in fruits and vegetables that are high in vitamin C.

Moderate alcohol use and reduce or stop smoking.

Keep an eye out for any adverse responses to dental products and stop using them if needed.

Conclusion: The treatment of white gums is contingent upon the underlying cause and general state of health. Frequent dental examinations are necessary for early detection and treatment. Ignoring symptoms might increase the risk of developing more severe conditions, such as oral cancer. Make oral health a priority by taking preventative steps to guarantee early intervention and reduce the likelihood of problems.

[sleepyspoonie]

i know you're mainly talking about hirsutism but i love talking about how fucked up medical care is for people with pcos so im here climbing into your reblogs. i have pcos and find it super interesting but also totally infuriating how it's treated

basically in terms of diagnosis, there are three pillars of symptoms: cystic ovaries, hyperandrogenism, and irregular ovulation. it's USUALLY the hyperandrogenism/hirsutism that gets you recommended for testing. my dermatologist advised me to get tested for that reason, but i also have cystic ovaries.

how do you treat pcos? well, that depends on how shitty your doctor is! i have a really good care team, but a very common experience for people with pcos is to be told to either lose weight or come back when you're trying to have a baby (the irregular periods and cystic ovaries cause fertility issues, and many people don't find out they have pcos until they're trying to get pregnant).

there are two reasons people with pcos are advised to lose weight:

pcos is correlated to higher body weights, and because doctors are fatphobic, they think most medical issues in fat people can be solved by weight loss

there was a very shitty study done, I want to say in the 90s but im not sure, that showed that weight loss in individiuals with pcos would improve egg quality. however, the study only went on for six weeks and had a statistically insignificant sample size, so it was functionally meaningless.

and yet that study has served as the backbone for all pcos care for years.

the thing i hate the most is basically that whether or not you're actually trying to get pregnant, a lot of people with pcos are given treatment meant to help them get pregnant rather than actually and meaningfully treating their symptoms

because here's the thing! pcos has a lot of symptoms! the name is kind of a misnomer, because people think it's just that you have cysts in your ovaries, but you literally don't need to have those. you just need 2 out of the 3 diagnostic criteria.

but if you have pcos? you're predisposed to insulin resistance and diabetes because your insulin receptors naturally don't work well. you may have hypothyroid or hyperprolactinemia. it's highly comorbid with mood disorders (80% of people with pcos also have at least 1 mood disorder). and if you get cysts, you can have painful ruptures or even situations where they can necrotize inside of you if they get too big (author's note: this sucks). you're also probably vitamin d deficient, and if you take medication for any of the above, you're probably vitamin b-12 deficient.

like i said, i have a good care team. i take 10 pills a day just to manage my pcos symptoms--never mind the rest of my pills, and not even counting the shit i take for my highly comorbid mood disorders (lol).

pcos basically affects every inch of your body, and it really gets brushed off as a dumb disease that doesn't really affect people in a substantial way, even though it super does. it's all about getting pregnant and not being fat or hairy, and that's horrible ):

I forget why, but I was on the Wikipedia page for polycystic ovarian syndrome, and I started researching hirsutism in women, and I learned the following things in this order:

there's a diagnostic criteria used to evaluate how hairy a woman is

This is important because being too hairy is a diagnostic criteria of most disorders that cause hyperandrogenism

Disorders that cause hyperandrogenism can be diagnosed by...measuring how hairy you are (this is the main and most important diagnostic criterion for PCOS)

Disorders that cause hyperandrogenism are important because they are correlated with obesity, infertility, and...being too hairy?

I think to myself, wait, what is a normal range for testosterone in women? I find this article...which set reference ranges for "normal" testosterone levels in women...EXCLUDING WOMEN WITH PCOS?

Quote: "Polycystic ovary syndrome (PCOS) is another notable condition in genetic (XX) females, which is characterized by excessive ovarian production of androgens. This condition is included for comparison with DSD, as the affected females with PCOS are genetic and phenotypic females. The elevated levels of testosterone in these females can lead to hyperandrogenism, a clinical disorder characterized variably by hirsutism, acne, male-pattern balding, metabolic disturbances, impaired ovulation and infertility. PCOS is a common condition, affecting 7%-10% of premenopausal women."

So: the study claims to demonstrate a clear distinction between the normal range of hormone levels in "Healthy" men and "healthy" women...with "healthy" being defined in the study as...having hormones within the "normal" range.......................

So I researched what the clinically established "normal" range for testosterone in women is

THERE ISN'T ONE????

Quote from the above article: "Several different approaches have been used to define endocrine disorders. The statistical approach establishes the lower and the upper limits of hormone concentrations solely on the basis of the statistical distribution of hormone levels in a healthy reference population. As an illustration, hypo- and hypercalcemia have been defined on the basis of the statistical distribution of serum calcium concentrations. Using this approach, androgen deficiency could be defined as the occurrence of serum testosterone levels that are below the 97.5th percentile of testosterone levels in healthy population of young men. A second approach is to use a threshold hormone concentration below or above which there is high risk of developing adverse health outcomes. This approach has been used to define osteoporosis and hypercholesterolemia. However, we do not know with certainty the thresholds of testosterone levels which are associated with adverse health outcomes."

What the fuck?

What the fuck?

It's batshit crazy to make a diagnostic criteria for medical disorders by placing arbitrary cutoffs within 2-5% of either end of a statistical distribution. What the actual fuck?

"The results came back, you have Statistical Outlier Disease." "What treatments are available?" "Well, first, we recommend dietary change. You should probably stop eating so many spiders."

Another article which attempted to do this

Quote: "Subjects with signs of hirsutism or with a personal history of diabetes or hypertension, or a family history of polycystic ovarian syndrome (PCOS) were excluded."

"We're going to figure out the typical range of testosterone levels that occur in women! First, we're going to exclude all the women that are too hairy from the study. I am very good at science."

Anyway I got off topic but there are apparently race-specific diagnostic tools for "hirsutism." That's kinda weird on its own but when I looked more into this in relation to race I found this article that straight-up uses the term "mongoloid"

[chicagopaincontrol]

How To Reduce Your Neuropathic Pain at Home

There are many different ways that people experience neuropathic pain. Some may feel a sharp stabbing pain in the middle of the night when they get up to get a glass of water from the kitchen. Others might encounter a tingling feeling or a constant pricking as they go about their daily activities, from getting dressed in the morning to completing small activities such as organizing around the house, making a meal, or taking out the trash. 

Pain can be localized or manifest as a minor irritation for some who have neuropathy, but everyone experiences it differently. Managing neuropathy pain when at home can be a great way to find relief, make daily tasks more pleasant, and provide you with the right tools to care for yourself while living with neuropathy. 

But what exactly is neuropathy and how does it impact the body? 

Neuropathy can come about from many different sources such as diabetes, chemotherapy, HIV/AIDS treatment. Neuropathy is a condition that causes a range of health problems that stem from damage to the peripheral nerves. While the nerve damage cannot be reversed, taking certain steps to prepare for and mitigate the pain can be done. If you find yourself struggling with your neuropathy symptoms but are unsure about what you can do about it to manage the pain at home, here are 3 treatments that will help. 

3  At-Home Treatment for Neuropathic Pain Management

1. Walk Regularly.

Don’t discount the ability to ward off the more painful elements of your neuropathy by walking. For people with peripheral neuropathy, exercising, using their muscles, and raising their breath rate are all excellent ways to stay active and build muscle strength.

Daily movement is beneficial for your overall health and is always recommended to live a healthy lifestyle. However, if your neuropathy impacts your feet or your lower legs, walking or light aerobic activities will greatly benefit your condition. Walking improves blood flow to the legs and feet, in addition to strengthening and toning your muscles, all while improving blood circulation. 

Daily movement and walking is a great way to mitigate further tingling, burning, or numbness that may develop if you have neuropathy due to diabetes or other conditions. 

2. Use Supplements.

Vitamin deficiency is one of the contributing factors to neuropathy suffering. Nutritional supplements, along with a healthy and balanced diet, are a great way to regulate the body and reduce neuropathic pain.  When we are not consuming enough nutrients and not absorbing them efficiently, our bodies will lack the foundational nutrients that it needs to perform various tasks, such as maintaining the nervous system, healing the body, and working effectively. 

To combat the lack of vitamins and nutrients your body receives on a daily basis, the following supplements may help to support your body against neuropathic pain:

Vitamin B-12: Any type of numbness, prickling, or tingling sensations that are typically sparked due to your nerve endings will benefit from a vitamin that supports the nervous system. Using the more potent form of Vitamin B-12, known as Methylcobalamin, the body can absorb this vitamin into the bloodstream to improve reflexes, lessen pain, pricking or tingling sensations, and provide overall nerve health. This vitamin also benefits the circulatory and immune systems. 

Vitamin D: Many patients with neuropathy have vitamin D deficiencies if they are diabetic or suffering from peripheral neuropathy. Typically people gain vitamin D nutrients from spending time in the sun, but depending on lifestyle, patients may have a varying opportunity to naturally get some rays. Instead, Vitamin D supplements may help improve the symptoms of those afflicted with diabetic neuropathy and help remedy the nutritional deficit in their diet. 

Omega-3 Fatty Acids: Ingredients found in foods such as fatty fish, algae, and high-fat fruit and vegetables, such as avocado, those deficient in omega-3’s can also take the supplement form. For patients with neuropathy, working this supplement into a daily regimen can help as an anti-inflammatory and decrease burning and numbness associated with pain. 

Make sure to consult with your doctor before adding any vitamins or supplements to your diet.

3. Take Care of your Feet.

Neuropathy in the feet is a common area to be affected for patients who are impacted by diabetic-induced neuropathy. These symptoms commonly affect the extremities of the body, especially tingling, loss of balance when walking, or burning sensations in the feet. 

Taking good care of your feet as someone who deals with neuropathy is the best way to prevent further nerve damage and muscle weakness from developing. 

Clean and manicure your feet every day. Keep your toenails short and manicured to avoid ingrown nails. After cleaning your feet, dry them with a soft towel, check for swelling, redness, or for signs of tear. If you find anything unusual on your toes or feet, make sure to report back to your physician or nurse. Foot moisturizer is also recommended to care for the skin on your feet. 

Wear the right footwear. Make sure that you are not going barefoot outside, or walking barefoot over hard surfaces. Support your heel, keep your feet inappropriate shoes, and avoid wearing ill-fitted socks or shoes to maintain good circulation. 

Managing Neuropathy Pain Requires a Collaborative Effort

Managing neuropathy takes a cyclical approach and cannot be solved with one form of treatment. Doing what you can at home to promote the best health including light exercise, utilizing the right supplements to aid in your nutrition, and maintaining your feet along with checking in with experts will support the best results. 

It’s important to enlist healthcare professionals who know how to treat neuropathy and your individual goals. At Integrated Pain Management, we design a program of wellness that fits your individual needs and treats your specific condition. Our dedicated healthcare professionals strive to create the most comfortable environment for their patients by working with them to curate an integrated pain management plan, fully customized to you. 

Your pain management program may include one or more of the conditions listed to the right. Click to learn more about each. If you have any questions, please contact our team to learn more, and to schedule an appointment with one of our specialists. 

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Revolutionizing Hemophilia Care: Emerging Trends in Drug Markets By 2023 to 2030

The global hemophilia a drug market is estimated to reach a value of US$ 21.07 billion by 2030, expanding at a CAGR of 6.6% from 2023 to 2030. Hemophilia A is a genetic bleeding disorder that affects the ability of blood to clot. This is caused by a deficiency of factor VIII, a protein that helps blood clot. People with hemophilia A experience frequent and easy bleeding, especially into their joints and muscles.

There are several different medications that can be used to treat hemophilia A. The most common type of treatment is factor replacement therapy, which involves replacing the missing factor VIII with a man-made or donated version. Factor replacement therapy can be given as an injection into a vein or muscle.

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Hemophilia A, a rare genetic disorder characterized by a deficiency in clotting factor VIII, poses significant challenges for individuals affected by the condition. The inability to control bleeding can lead to joint pain, internal bleeding, and even life-threatening complications. However, the Hemophilia A Drug Market is witnessing a surge in growth, driven by advancements in treatment modalities and an increasing focus on improving patient outcomes.

Other Medications That Can Be Used to Treat Hemophilia A Include:

Desmopressin (DDAVP): This medication is a synthetic hormone that can help to release factor VIII from the body's storage sites. It is typically used to treat mild to moderate hemophilia A.

Emicizumab (Hemlibra): This is a newer medication that is a bispecific monoclonal antibody. It works by mimicking the function of factor VIII and helping to control bleeding. Hemlibra is approved for use in people with hemophilia A with and without factor VIII inhibitors.

Antifibrinolytics: These medications work by slowing down the breakdown of blood clots. They are typically used to treat bleeding in the mouth or after surgery.

The specific medication that is used to treat hemophilia A will depend on the severity of the individual's condition and their response to treatment. It is important to work closely with a healthcare provider to determine the best treatment plan for each individual.

Future Outlook and Key Trends:

The Hemophilia A Drug Market is poised for continued growth in the coming years. Key trends that will shape the market include:

Personalized Medicine: The development of personalized treatment plans based on individual patient characteristics will gain prominence.

Gene Therapy: Gene therapy is expected to play an increasingly crucial role in the treatment of Hemophilia A, offering a potential cure for the condition.

Emerging Markets: Emerging markets will present significant growth opportunities for hemophilia A drug manufacturers.

Key Takeaways:

The global hemophilia A drug market is expected to reach US$ 21.07 billion by 2030, expanding at a CAGR of 6.6% from 2023 to 2030.

The increasing prevalence of hemophilia A, the rising demand for novel therapies, and the growing adoption of gene therapy are the key drivers of market growth.

North America is the largest market for hemophilia A drugs, followed by Europe and Asia Pacific.

Regional Outlook:

North America is the largest market for hemophilia A drugs, due to the high prevalence of the disease and the presence of a large number of pharmaceutical companies.

Europe is the second largest market for hemophilia A drugs, due to the increasing prevalence of the disease and the growing adoption of novel therapies.

Asia Pacific is the fastest growing market for hemophilia A drugs, due to the rising demand for novel therapies and the growing adoption of gene therapy.

Key Players:

Roche

BioMarin

Pfizer

Novo Nordisk

CSL Behring

Segmentation:

By type:

Hemophilia A

Hemophilia B

By treatment type:

On-demand,

Prophylaxis

By therapy:

Factor replacement therapy

Gene therapy

Monoclonal antibodies

By distribution channel:

Hospital pharmacies

Retail pharmacies

By region:

North America

Europe

Asia Pacific

Latin America

Middle East and Africa