#ykl 20
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Yuki Kajiura LIVE Vol.20 ~Japanese Seal 20th Special~ Live Audio [GDrive]
audio ripped from @putschki1969's provided video of ykl20 uploaded on bilibili by user 蓝原延珠_
do tell me if there's anything wrong with the audios!!
the audio quality isn't the best since it came from a tv broadcast
#yuki kajiura#fictionjunction#upl#live audio#live#link#gdrive#Yuki Kajiura Live vol. 20~Japanese Seal 20th Special~#ykl 20#yk live 20#yk vol 20#ykl vol 20#joelle#keiko#kaori#yuriko#yuriko kaida#kaori oda#keiko kubota#kalafina#fj#klf
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🛫🇹🇭Bangkok Trip🇹🇭🛫
My flight to Bangkok leaves tonight. I am quite nervous but also excited. Will be spending a few days there to do touristy stuff and then of course I will be attending the YKL Vol.20 concert on Friday. Super hyped to see Keiko and Hikaru on stage again. It's been almost a year since I saw them the last time.
Not sure if I will be able to do regular updates. I also might miss some stuff while I am stressing out over random travel stuff. Please bear with me!🙇♀️
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YKL vol#20, Asia Tour Special in KL, Malaysia diary time~
Bought VIP ticket. Sat 4 rows away from stage, kinda loud but glad i brought ear plugs.
Arrived there and retrieved the signed poster. And waited for 3 hours just to go in.
Imagine saying doors will be open at 6.00pm but only at 7.50pm due to "technical issue". We waited at B2 and it was getting very stuffy in the air. I thought i was getting no oxygen and abt to faint anytime.
I think out all the Asia concerts, only this one uses e-ticket instead of having a physical ticket.
Concert started right after everyone is sitted.
Oh, no photos or video recording is allowed btw. and we couldn't give gifts too :(
Yuki Kajiura san and her musician came out first then only the songstresses.
Yuki Kajiura kept saying sorry that the show was delayed and she even said she felt fed up with the situation. She was also very excited to finally eat some of our local food and she loved it. but didnt get a chance to see our city due to the show's schedule.
It was great to see the singers learn a bit of Malay to greet us.
I can see Keiko was trying her best to say as much as she can.
It was nice to see Joelle again, and to see her to sing majority of the songs was surely a wow factor.
Yuriko Kaida singing was great tho she seems a bit stiff on stage.
Hikaru was surely in her zone when she was singing and I love her energy even tho she sang a few songs only.
For rito and LINO LEIA, their performance was enjoyable despite being young. Hope the lady boss give them more songs to sing live.
Let's not forget, her musicians were great as well. They sure played well and i was bopping my head most of the time.
At the end, lady boss ensure her team to say correctly "See you again" in Malay before they say it together and bow before leaving the stage.
I had an awesome time with the show but i shared the same opinion with everyone on the show's management and how it was so disorganized and just terrible. Not only they made us wait but they didnt even bother to give us refreshments.
I didnt bother to take a selfie at the end cuz i was rushing to catch the train and have a morning shift the next day. haha writing this post now in my workplace.
that's all from me. Anyone who went to concert, pls do share your opinion.
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ことのほかやわらかい and Parade from YKL#20 were a lot better than YKL#19 tho. idk how much studio magix was involved but Kaori was less push-y with her voice. Yuriko's part in ことのほか was also a lot better. ofc the songs I liked the most ended up being the Japanese ones in a Japanese sealed live lmao
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Edit: The link is currently deleted bc I'm planning to change some things for the AU. The draft is still on my laptop, only I haven't uploaded it just yet.
Major changes:
-Characters are aged up to early 20s to fit the workplace setting.
-Fanservice is still there but not too lewd.
-More characters will be added. Including Morfonica and RAS. I haven't known a lot about MyGo and Ave Mujica members yet.
-The story has 2 sections: main story and side story.
Minor changes:
-(Romantic) Ships will be mainly TomoYuki and SayoTsugu/SayoLisa focus.
-Friendly reminder: I personally don't ship ykls, I headcanon them as close friends and that's it. Platonic ship for the win!
To be honest this upcoming fanfic is still not 100% accurate though.
Bandori/BanG Dream Hospital AU: Character Introductions
Starlight Hospital is one of the biggest and most prestigious hospitals in town. All the doctors, nurses, pharmacists and the personnel are very nice. But, some fun and boppin’ stuff tend to happen here, of course…
There haven’t been any Hospital AUs that has some sprinkles of yuri/girl x girl. And I’m making one of this!
LINK : click here
Keep reading
#bandori#bang dream#fanfic#tbh i might continue this#i'm back into bandori but on hiatus when playing the game#but i lowkey need tomoyuki food lmao
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Amazon Prime actress Brooke Lewis Bellas shares 20+ years of show business experience with Casting Frontier.
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RT @kikiki04: 今日YKL追加公演の当落ですが、明日1日限定でOrigami payが20%引き最大1000円引きのクーポンを3枚配っているので、当選したら明日ローソンでOrigami payで支払うとチケット代が1000円引かれてOrigami payで決済されます。 https://www.youtube.com/c/lifesang
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Báo giá bồn tắm đứng tại Hà Nội Cuộc sống ngày càng phát triển thì mong muốn có một phòng tắm để thư giãn sau một ngày làm việc căng thẳng là rất cần thiết. Bởi sử dụng bồn tắm đứng không nhưng làm cho không gian phòng tắm của gia đình bạn trở lên đẹp và sang trọng hơn mà nó còn giúp cho sàn nhà tắm của bạn luôn luôn được sạch sẽ và khô ráo suốt cả ngày. Chính vì vậy mà bồn tắm đứng hiện đang được rất nhiều gia đình lựa chọn, bồn tắm đứng kiểu dáng hiện đại với kích thước đa dạng có thể lắp đặt phù hợp với m���i không gian phòng tắm khác nhau. Trên thi trường hiện nay có nhiều hãng bồn tắm đứng cũng như giá cả của mỗi nơi bán là khác nhau . Vậy bài tư vấn này Bếp Nam Anh xin giới thiệu đến quý khách bài viết " báo giá bồn tắm đứng tại Hà Nội " Bồn tắm đứng có rất nhiều mẫu mã với xuất xứ và giá cả khác nhau, từ hàng nhập khẩu nguyên chiếc từ Malaysia, Hàn Quốc đến các loại bồn tắm liên doanh giá rẻ cho người tiêu dùng nhiều sự lựa chọn. Hiện tại Giá của bồn tắm đứng được chia ra làm ba yếu tố sau : + Nguồn gốc xuất xứ : Hàng nhập khẩu sẽ có giá thành cao hơn so với dòng sản xuất và lắp ráp tại Việt Nam + Kích thước và kiểu dáng : Kích thước to sẽ đắt hơn kích thước nhỏ , và loại kiểu dáng đế cao sẽ đắt tiền hơn dòng đế lửng và đế thấp . + Chất liệu : Chất liệu đế trắng thường sẽ có giá thành rẻ hơn so với các dòng đế được làm bằng chất liệu ngọc trai . Bồn tắm đứng là loại bồn tắm có cấu tạo gồm 2 phần đó là phần đế và phần khung. Trong đó phần đế được làm bằng chất liệu Acrylic hoặc Acrylic ngọc trai một số thương hiệu được làm bằng chất liệu Composte thường. Phần khung được làm bằng khung nhôm cao cấp bao quanh là hệ thống kính cường lực màu xanh hoặc kính màu trong suốt. Bồn tắm đứng có thiết kế cửa lùa hoặc cửa mở tiện lợi cho việc sử dụng. Kiểu bồn tắm đứng dùng vách kính không chỉ có tác dụng làm liền mạch không gian phòng tắm của gia đình bạn mà nó còn giúp cho căn phòng vốn nhỏ sẽ không bị chia vụn ra mà còn tạo được sự ngăn cách giữa khu vực khô và ướt của phòng tắm. >>> Để giúp quý khách có thể dễ dàng lựa chọn sản phẩm bồn tắm đứng cho phù hợp, Bếp Nam Anh xin gửi tới quý khách hàng báo giá môt số thương hiệu bồn tắm đứng đang được ưa chuộng trên thị trường hiện nay. *** Thứ nhất chúng ta cùng tìm hiểu về các loại bồn tắm đúng nhập khẩu cao cấp. Giá thành của những dòng sản phẩm này được chia ra làm hai phân khúc giá : Giá giao động trong khoảng từ 5-10 triệu đồng , và loại từ 10 - 20 triệu đồng . Sau đây chúng tôi BẾP NAM ANH xin giới thiệu tới khách hàng một vài hãng và model bồn tắm đứng nhập khẩu cao cấp đang được khách hàng lựa chọn . 🔷 Đầu tiên phải kể đến thương hiệu bồn tắm đứng Daros cao cấp , sản phẩm được nhập khẩu từ Hàn quốc có nhiều mẫu mã , kiểu dáng đệp cùng đó là kích thước khá là đa dạng nên hãng bồn tắm đứng này mấy năm trở lại đây được khá nhiều khách hàng quan tâm và lựa chọn cho phòng tắm của gia đình bạn. Các mẫu bồn tắm đứng của Daros có kích thước khác nhau như : 800x800x1850, 900 x 900 x 1850mm, 1000 x 1000 x 1850mm, 1100 x 1100 x 1850 mm, 1200 x 800 x 1850 mm, 1200 x 800 x 1850 mm...Bồn tắm đứng nhập khẩu Daros có cấu tạo phần khung bằng Inox có khả năng chống han gỉ và có độ bền cao. Cùng đó là kính cường lực dày 8mm. Bồn tắm đứng Daros có giá dao động hơn 10 triệu đến 20 triệu đồng. Quý khách có thể tham khảo một số mẫu bồn tắm đứng Daros . Bồn tắm đứng Daros DR-16-21 có 2 loại kích thước tương ứng là: kích thước 900*900*1850 mm, và kích thước : 1100*1100*1850 mm tương ứng với chiều dài x chiều rộng x cao của bồn. Chân bồn được làm từ chất liệu Inox có chân có yếm, đây là chất liệu Inox cao cấp, loại Inox không nhiễm từ có khả năng chống oxy hóa và chống gỉ sét tốt nhất hiện nay. Bao quanh thân bồn được làm bằng kính cường lực dày 8mm chịu lực chịu nhiệt tốt. Giá của Bồn tắm đứng Daros DR-16-21 giao động khoảng hơn 10 triệu tùy từng kích thước và chất liệu đế bồn. Tất cả sản phẩm bồn tắm đứng của Daros đều được được bảo hành 36 tháng phần thân bồn, 1 năm thiết bị khác. 🔷 Thương hiệu thứ hai chúng ta không thể không nhắc đến đó chính là thương hiệu Bồn tắm đứng Govern. Bồn tắm đứng Govern là một trong những thương hiệu bồn tắm đứng đang được khách hàng lựa chọn nhiều nhất hiện nay. Bồn tắm đứng Govern được nhập khẩu nguyên chiếc từ Malaysia, có kiểu dáng mẫu mã đa dạng. Sản phẩm có cấu tạo phần đế bằng chất liệu Acrylic hoặc Acrylic ngọc trai có khả năng chống bám bẩn, chống ẩm mốc, chống trầy xước cao, dễ lau chùi vệ sinh. Phần khung được làm bằng hệ thống khung nhôm bao quanh là hệ thống kính cường lực, chịu lực có màu xanh hoặc màu trắng trong suốt. Sản phẩm bồn tắm đứng Govern có kiểu dáng, mẫu mã, kích thước đa dạng với mức giá dao động từ 6 triệu->20 triệu. Quý khách có thể tham khảo một số mẫu bồn tắm đứng Govern bán chạy trên thị trường hiện nay như : Bồn tắm vách kính Govern JS-8137, Bồn tắm đứng Govern LV-91, Bồn tắm Govern JS-320 ..v.v - Đặc biệt hơn là mẫu Bồn tắm đứng Govern YKL PA90. Đây là mẫu bồn tắm đứng cao cấp của thương hiệu Govern có chất liệu đế bằng Acrylic màu vàng chanh với kích thước là 900 x 900 x 2050. Bồn tắm đứng Govern YKL PA90 có thiết kế cửa lùa sang 2 bên tiện lợi cho việc sử dụng. Giá của sản phẩm bồn tắm đứng Govern YKL PA90 là hơn 13 triệu đồng . 🔷 Với kích thước: 1200 x 800 x 2050 (mm) : tương ứng với chiều dài x chiều rộng x chiều cao, bồn tắm đứng Govern JS-8137 nhỏ gọn thích hợp với không gian phòng tắm hẹp. Bồn tắm đứng Govern JS-8137 được thiết kế với kính trắng cường lực chịu lực chịu nhiệt tốt dày 8mm, cửa kéo hiện đại, chân đế và thành bồn được làm bằng chất liệu Acrylic trắng dễ vệ sinh và không bám bẩn . **** Thứ hai là các dòng sản phẩm bồn tắm đứng giá rẻ được sản xuất và lắp ráp tại Việt Nam . Những mẫu bồn tắm đứng của các thương hiệu này có mức giá giao động trong khoảng từ 2 đến 5 triệu đồng và 5 đến 10 triệu đồng . Quý khách có thể tham khảo thương hiệu bồn tắm đứng của Fantiny . 🔷 Thương hiện bồn tắm đứng của Fantiny , một sản phẩm bồn tắm đứng được sản xuất tại Việt Nam, sản phẩm của thương hiệu này không có quá nhiều mẫu mã cho khách hàng lựa chọn, nhưng mỗi sản phẩm bồn tắm đứng của Fantiny đều được các nhà sản xuất tỷ mỷ trên dây chuyền công nghệ hiện đại nhất nên sản phẩm này có kiểu dáng chắc chắn , độ bền cao , điển hình như model này Bồn tắm vách kính Fantiny MBG-90S, được thiết kế kiểu dáng góc với kích thước: 900x900x2100mm thích hợp với những không gian phòng tắm có diện tích nhỏ. Bồn sử dụng chất liệu kính cường lực dày 8 mm chịu nhiệt, chịu lực, có đế màu trắng làm bằng chất liệu nhựa composite dễ dàng lau chùi và vệ sinh. Giá của dòng sản phẩm bồn tắm đứng của Fantiny có giá gioa động trong khoảng từ 6 đến 8 triệu đồng tùy từng mẫu . Trên đây là các thương hiệu bồn tắm đứng và model được khách hàng tin và sử dụng nhiều. Còn với mỗi loại bồn tắm đứng khác nhau sẽ có giá cả khác nhau tùy thuộc vào loại chất liệu và xuất xứ, nhưng nhìn chung giá của bồn tắm đứng thường dao động ở mức trên 5 triệu đến 20 triệu đồng. Do đo tùy thuộc vào nhu cầu sử dụng và điều kiện kinh tế của mỗi gia đình mà bạn có thể lựa chọn cho gia đình mình một sản phẩm phù hợp. Để được tham khảo trực tiếp tất cả các sản phẩm bồn tắm đứng cao cấp quý khách hãy đến với Bếp Nam Anh. Quý khách đến với Nam Anh ngoài được tham khảo trực tiếp sản phẩm bồn tắm gia đình thì còn nhận được nhiều ưu đãi và hỗ trợ tốt nhất như: được tư vẫn chọn mua sản phẩm bồn tắm phù hợp nhất, được hỗ trợ khảo sát và vận chuyển miễn phí trong nội thành Hà Nội. Ngoài ra quý khách còn nhận được nhiều chương trình khuyến mại với nhiều phần quà giá trị. #bepnamanh https://ift.tt/2KVZZIP
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Expression of M2 macrophage markers YKL-39 and CCL18 in breast cancer is associated with the effect of neoadjuvant chemotherapy
Abstract
Purpose
High activity of enzyme TOP2a in tumor cells is known to be associated with sensitivity to anthracycline chemotherapy, but 20% of such patients do not show clinical response. Tumor microenvironment, including tumor-associated macrophages (TAM), is an essential factor defining the efficiency of chemotherapy. In the present study, we analyzed the expression of M2 macrophage markers, YKL-39 and CCL18, in tumors of breast cancer patients received anthracycline-based NAC.
Methods
Patients were divided into two groups according to the level of doxorubicin sensitivity marker TOP2a: DOX-Sense and DOX-Res groups. Expression levels of TOR2a, CD68, YKL-39 and CCL18 genes were analyzed by qPCR, the amplification of TOR2a gene locus was assessed by the microarray assay. Clinical and pathological responses to neoadjuvant chemotherapy were assessed.
Results
We found that the average level of TOP2a expression in patients of DOX-Sense group was almost 10 times higher than in patients of DOX-Res group, and the expression of CD68 was 3 times higher in the DOX-Sense group compared to DOX-Res group. We demonstrated that expression levels of M2-derived cytokines but not the amount of TAM is indicative for clinical and pathological chemotherapy efficacy in breast cancer patients. Out of 8 patients from DOX-Sense group who did not respond to neoadjuvant chemotherapy (NAC), 7 patients had M2+ macrophage phenotype (YKL-39+CCL18− or YKL-39−CCL18+) and only one patient had M2− macrophage phenotype (YKL-39−CCL18−). In DOX-Res group, out of 14 patients who clinically responded to NAC 9 patients had M2− phenotype and only 5 patients had M2+ macrophage phenotype. Among pathological non-responders in DOX-Sense group, 19 (82%) patients had M2+ tumor phenotype and only 4 (18%) patients had M2− phenotype. In DOX-Res group, all 5 patients who pathologically responded to NAC had M2 phenotype (YKL-39−CCL18−). Unlike the clinical response to NAC, the differences in the frequency of M2+ and M2− phenotypes between pathologically responding and non-responding patients within DOX-Sense and DOX-Res groups were statistically significant.
Conclusions
Thus, we showed that in patients with breast cancer who received anthracycline-containing NAC the absence of clinical response is associated with the presence of M2+ macrophage phenotype (YKL-39-CCL18 + or YKL-39 + CCL18-) based on TOP2a overexpression data.
https://ift.tt/2FJrtz3
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theres no live audios for ykl 20 yet so ill try and do those later when i get home
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🇹🇭YKL vol.#20 ~Asia Tour 20th Special SETLIST~ 【Bangkok】 Live Report🇹🇭
Wow, what a week it has been. My Thailand trip was an exciting but very exhausting experience. I'm finally back home and after spending an entire day just relaxing on Tuesday, I feel somewhat ready to tackle this live report. I'm back to work and there's a lot to do but I still want to post as much as possible before I lose all of my motivation. Still took me several days to finish this so I am sorry for the delay🙏 I'll start with some general stuff from the day of the live and then continue with a detailed report. Without further ado, let's get to it〈(•ˇ‿ˇ•)-→
Before The Live
The concert was held on November 15th at Bangkok Union Hall. At that point I had already been in Thailand for two and a half days doing all sorts of Kalafina and touristy stuff. Needless to say, I was quite exhausted from my previous activities (more on that in a future post) but I was determined to enjoy the day to the fullest. The only major thing planned for that day was a meet-up with some fellow fans to get lunch and dinner so thankfully, nothing too strenuous. Although one could argue that social interactions like this are always a big struggle for me :P Anyway, I headed to the venue quite early in the morning to meet my friends. We were doing some last-minute shopping at a nearby mall to complete the presents for Keiko and Hikaru. Also, we wanted to check out our flower stand which had been put up earlier that morning. I was beyond happy to participate in this particular flower stand project. The HiKei chibis turned out super cute and the banner was also adorable (just look at little Moo Deng🦛). I'm a little bummed though that I didn't get to take the cardboard print home with me since the girls requested the flower stand to be brought to their dressing room after the live (initially, we had planned to take all the decorative stuff off the flower stand after the concert before the flower shop picked it up but alas, it wasn't meant to be). Oh well, we got all those sweet pics with Keiko and Hikaru so that pretty much erased any feelings of disappointment. Thankfully, I got my acrylic key-holders and stickers as a little consolation. I will certainly treasure them forever. During the meet-up with some fellow fans, I also got a bunch of presents, including some gorgeous fan-made articles for the two lives in China. Honestly, I feel so blessed to have received all of this. Thank you so much to everyone who thought of me!
Speaking of fellow fans, I appreciated everyone who came up to me to say "hi". I was also very happy about all the yummy souvenirs. The suncakes from Taiwan saved my life during the following days because I always had a lovely snack to accompany my morning coffee. Sorry if I came across as awkward or reserved to some of you, I am not used to being in big crowds like that and meeting strangers is not among my strengths. Also wish I had gotten more commemorative pics with everyone but oh well, in the heat of the moment it's easy to forget about stuff like that.
For lunch we had planned to go to a Hainanese Chicken place but unfortunately, they didn't have enough room for our group so we ended up going to KFC XD. I forgot to take pictures but our order was honestly not that exciting anyway. I was so eager to try spicy food during my stay in Bangkok but that stuff at KFC was a total let-down (probably our fault though for not looking properly at the menu - they may have had some spicier stuff that we just didn't see). Dinner that day more than made up for it though since my main dish was incredibly delicious. Don't ask me what it was called, it was some sort of fried pork concoction with garlic and chili, simply fabulous and probably one of the best things I had during that trip.
Despite having a lot of fun during these activities, I kinda regret not being able to see anything of the Loy Krathong festivities that day. The weird timing of the concert would have made it very inconvenient to check out any of the festival sites and on top of that there were some bad weather forecasts so no one wanted to risk getting wet😢 It's a real shame but oh well, I guess the live was worth it.
♪The Live♪
Seat
I was very lucky to have dedicated friends who made sure I'd get a VIP front-row seat right across from Keiko's spot on the stage [the picture below was taken at the end of the concert when I was already walking outside so it doesn't properly reflect my point of view - I was seated a little more to the right side]. She was pretty much right in front of me during the entire live so of course, I was in heaven. Taking my eyes off her was a real challenge and at times I honestly felt a little bad for the other singers because I didn't really pay that much attention to them whenever Keiko was on stage. Also, this might make me sound like a perv but I was absolutely mesmerised by Keiko's legs. During her main solo parts she would always turn to the side or turn her back to the audience. Not sure why (maybe because so the audience would focus on her singing rather than her gorgeous face? Or she was a little self-conscious? Who knows). Either way, during these parts her legs were on full display and since her skirt was quite short on one side, you could basically get a glimpse of her tiny safety shorts with every tiny move she made 🫣
One tiny complaint I had was that the stage was quite far away from the audience area and they even felt the need to put up a relatively high metal barrier which created a weird sense of distance despite being all the way up in the front. Nevertheless, the concert felt very intimate to me and I think for that reason, I enjoyed it much more than my past Yuki Kajiura live experiences. I also gained a new appreciation for certain songs that I previously didn't care for all that much. I honestly can't stress this enough, experiencing a concert like this in such an intimate manner is vastly superior to watching a DVD/BD/live stream or even attending it in a spot somewhere further away from the stage. Everything feels and sounds completely different. Your entire body is getting caught in this spectacle and you get a full-on adrenaline rush. It's during these moments when I barely notice any flaws or mishaps. I've been made fun of in the past for always writing these overly positive and raving reviews of concerts but I personally don't even notice half of the bad stuff when I am on such a high. Plus, I don't enjoy lingering on the negative stuff which is why you won't see much of that in any of my reports.
Venue
To be fair, it wasn't a particularly good concert hall, at least in my opinion. The venue was a lot smaller than expected and it felt more like a convention hall rather than a proper concert hall. There are much better venues available in Bangkok but they were probably already booked or too expensive. Also, from what I've heard, the concert tickets didn't sell that well so it was probably a good thing that they stuck with this sort of venue. At any rate, it was very conveniently located at a MRT/BTS station so yay for that. The acoustics were decent enough I guess but nothing to write home about. The sound system could have used some improvements though, I don't think the instruments and vocals were very well-balanced throughout most of the concert. But maybe that could be chalked up to my position in the audience. Just a little disclaimer here, I am not very tech-savvy in that regard but on more than one occasion I noticed that the sound was kinda off...Mind you, not to an extent that would have taken away from my overall enjoyment of the concert but enough for me to notice it several times.
Setlist:
the world: Will always prefer Keiko on main but it is what it is, Joelle on main is fine too. It's a good song so it's a treat to hear it live no matter who is leading. The harmonies at the end didn't quite work for me. Was a bit all over the place. I think the sound system was at fault here.
in the land of twilight, under the moon: Not usually one of my faves but I thoroughly enjoyed this rendition.
vanity: What a blessing to hear this live in concert again! My first time was in Taiwan and I don't think I ever recovered from it. Correct me if I am wrong though but they made a big change during the performance regarding Keiko's epic yayayay part. She flawlessly did her solo of course but then when Joelle starting to sing that final chorus, she didn't continue to sing in the background which she would usually do. I found that very unusual. Also checked the bootleg recordings from the live in China and she did the same thing there too. Huh...Since when did they change it? That was a bit of a bummer to be honest since the very final part felt less epic because of it.
My long forgotten cloistered sleep: So, so good!! Huge fan! Joelle is getting better at it too so I am enjoying her version more and more.
I swear: Wow, what a revelation! I did not expect to suddenly fall in love with this song. I am obviously a huge Keiko-stan but due to her using her cutesy voice in this, it's never really appealed to me. It's always been one of those songs that I preferred to skip during re-watches of home video releases because it didn't really do anything for me. This time though, it felt like Keiko was serenading me specifically (a delusion on my part of course but let me have that little fangirl moment XD). Anyway, this is what I meant earlier. All of a sudden, a song has a new meaning to you and it's only because you get to experience it on such a personal level. The lyrics couldn't be more appropriate: "♪I know, I’m in love♪"
fiction: Not my cup of tea so I tend to skip this but Joelle in particular always does a great job with this song. Her voice is a perfect fit. Definitely my favourite performance so far because I was more into it than usual.
I reach for the sun: Love, love, love.
in the garden of sinners: Damn it, this one hurt so much, I literally almost cried. I don't even really know why but I could barely handle it. All I wanted to hear was Wakana together with Keiko and honestly, it was her voice in my mind, Joelle didn't exist for me in those moments. No matter what happens, I will always associate these melodies with Wakana and Keiko. On one hand, this performance made me incredibly sad but on the other hand, it made me feel even more grateful about the upcoming Kalafina Anniversary Live. Just the thought of hearing the three of them together again is bringing tears to my eyes.
ARIA: What a shame. I knew what to expect of course but it still hurt to hear Joelle sing the chorus. Unlike others, I didn't think that Hikaru sounded all that bad so she could have definitely handled the chorus (especially being backed by Keiko). She might not have sounded her best but who cares?! This is HER song so she should be in the lead. Period. I remember someone saying that Yuki wanted to go back to the original key (more of a speculation, as far as I know, it's not actually confirmed) so she gave the chorus to Joelle but Joelle was kinda struggling with it too so ultimately, we didn't really gain anything from having her in the lead. On a side note, I am just so relieved that Keiko and Joelle didn't do the infamous arm gesture that Wakana and Keiko used to do all the time. All of this sounds rather negative but to be honest, I still liked the performance despite being a little disappointed with the vocal arrangement. it's one of my all-time favourite Kala-songs so it's always a pleasure to hear it.
Magia: By now I am used to the FictionJunction cover version of this and it's really quite good. Solid performance. No notes.
Kimi no Gin no Niwa: Again, good stuff but since I don't particularly like the song it was just okay to me.
ring your bell: Ugghhh, probably my least favourite performance of the night. It's such a difficult song to perform and I honestly don't even like most of Kalafina's live versions but this one was hard to get through. Maybe the sound system was to blame a bit because LINO LEIA's microphone did some weird stuff that made her singing sound worse than it probably was. Plus, I honestly don't think she is a very good fit for the song. Hell, not even Wakana is a good fit for the song 90% of the time. For some reason, LINO LEIA kept using her more generic singing voice when instead, she should've opted for a more controlled head voice. Towards the end we heard a more solid delivery but the rest was unfortunately a bit messy.
to the beginning: Okay I guess. It's certainly one of the better Kalafina covers they do at YKL because Joelle and Yuriko add a lot of dimension. And since I have never been a fan of the song to begin with, it's not like I am missing Wakana too much.
Yasashii Yoake: The See-Saw section of the live was so much more fun than I had expected. Actually really surprised how much I enjoyed it since I am not too familiar with Yuki's old work and don't usually listen to any of it. Also, with Keiko not playing a big role in this corner, I thought I wouldn't be into it. But I guess the songs are just really good with catchy melodies so I couldn't help but like them. Also, my proximity to the stage once again helped me to have a bit more appreciation for the music. All three songs were featured at Kaji Fes. but I don't recall them leaving a huge impression on me. Back then I didn't mind them but I didn't get too excited. This time, I was having a great time from the get-go. Love the Joelle/Yuriko duo here. Joelle's voice works super well for this type of song.
Obsession: I remember not being particularly impressed by the Kaji Fes. performance but the Bangkok version was so cool. LINO LEIA and Keiko did a great job. So cool!! After that rather mediocre "ring your bell" performance, it was nice to hear LINO LEIA sing in a more comfortable range.
Senya Ichiya: Starting to love rito's vocals more and more. She's so criminally underused during these lives. Despite being promoted to "regular" singer, she really doesn't get to do much.
the main theme of “L.O.R.D”: One of my all-time faves. Joelle's best song if you ask me. Will never get tired of hearing it. Although I feel like at this point Joelle had already run out of steam a little because the performance didn't quite hit the spot in terms of oomph-factor. I think it's because Joelle had to carry 90% of the show and was thus running on low-heat towards the end. Still had a blast!
absolute configuration: Love having all the girls on stage for these sort of epic battle songs. Gorgeous harmonies.
luminous sword: Same as above. Perfect transition and a lovely continuation of the epicness.
蒼穹のファンファーレ: Typically not one of my favourite songs but yet again, I found myself enjoying it more than I usually would. The heat on stage was contagious so I simply got swept away in the excitement.
En. the image theme of Xenosaga II: Don't remember much of this but it was nice.
En.nowhere: Wow, wow, wow! What an amazing performance. So much more energised than during the Kaji Fes concert. Definitely one of the songs where I very much appreciated my closeness to the stage. I could really feel the heat and had such a blast, especially when Keiko began to really interact with the audience. Almost made me want to stand up but in the end, I remained seated (really not the type to move a lot during a concert). I have to agree with everyone who has already shared their thoughts on the other Asia live performances, this was definitely one of the highlights for Hikaru as far as her vocal delivery was concerned. Her voice was very powerful here.
En.into the world: I love that this has become almost a staple of YKL. It's such a gorgeous song with a beautiful message and I think Joelle as well as Yuriko manage to improve the overall harmonies with their added vocals.
#kalafina#kajiura yuki#yuki kajiura#keiko#hikaru#report#live report#fictionjunction#ykl vol 20#long text post#personal
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hmmm despite the concert having the most fresh setlist we've gotten in awhile, i still think YKL#20 is pretty boring lol
the best part of the live was obawo and sato using actual kitchen appliances for kitchen main theme. Eri was brilliant as usual and Joelle in fiction will never not be phenomenal. even better now that Keiko was the one singing the harmony for fiction. the english section was kinda sleep inducing ngl.
should've sneaked in sis puella magica somewhere in the setlist (maybe cut hepatica from the setlist). stage design was weird, Kajiura in the middle is kinda fitting i guess but also made for a very weird standing position for the ladies, especially on the English section where for the most part there were only Joelle, Keiko, and Yuriko Kaida there. everything was so red that it was kinda tiring for the eyes. again, a proof that stage design, lighting, and costume are afterthoughts in YKL. that YKL#20 logo is still ugly af.
camerawork and video edit are not the best but also kinda better than YKL#19 bcs this one has better shots on each vocalist (Yuriko got so many solo shots!!), unlike YKL#19 which has the most random Joelle shots all the time (maybe bcs lady was too over the top with her body movement lmao)
overall a decent live that i won't rewatch often (as the case with YKL#16, 17, and 19). the rewatch-ability value of YKL are usually pretty low so nothing new there.
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Preclinical amyloid pathology biomarker positivity: effects on tau pathology and neurodegeneration.
IoN UCL PubMed: Preclinical amyloid pathology biomarker positivity: effects on tau pathology and neurodegeneration.: Preclinical amyloid pathology biomarker positivity: effects on tau pathology and neurodegeneration. Transl Psychiatry. 2017 Jan 10;7(1):e995 Authors: Höglund K, Kern S, Zettergren A, Börjesson-Hansson A, Zetterberg H, Skoog I, Blennow K Abstract Brain autopsy and biomarker studies indicate that the pathology of Alzheimer's disease (AD) is initiated at least 10-20 years before clinical symptoms. This provides a window of opportunity to initiate preventive treatment. However, this emphasizes the necessity for biomarkers that identify individuals at risk for developing AD later in life. In this cross-sectional study, originating from three epidemiologic studies in Sweden (n=1428), the objective was to examine whether amyloid pathology, as determined by low cerebrospinal fluid (CSF) concentration of the 42 amino acid form of β-amyloid (Aβ42), is associated with biomarker evidence of other pathological changes in cognitively healthy elderly. A total of 129 patients were included and CSF levels of Aβ42, total tau, tau phosphorylated at threonine 181 (p-tau), neurogranin, VILIP-1, VEGF, FABP3, Aβ40, neurofilament light, MBP, orexin A, BDNF and YKL-40 were measured. Among these healthy elderly, 35.6% (N=46) had CSF Aβ42 levels below 530 pg ml(-1). These individuals displayed significantly higher CSF concentrations of t-tau (P http://dlvr.it/N4xphY
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2024/12/13 Instagram post by Keiko
💙🇨🇳🇹🇭🇲🇾🖤(Source)
I love how Keiko has started to use hearts in different colours for all three of them. She does it on Yodel too. Hikaru = BLUE, Wakana = WHITE and Keiko = BLACK
『Hikaru LIVE TOUR -ROUND-』 Miyagi
The third concert of Hikaru’s solo tour was successfully finished today. Tweet by Hikaru | Instagram story by Hikaru | Instagram post by Hikaru |
▼2024 11/30 (Sat) Soul Power, Toyama 17:30 / 18:00 12/07 (Sat) Music Bar Perch, Aichi 17:30 / 18:00 12/14 (Sat) LIVE HOUSE enn 2nd, Miyagi 17:30 / 18:00 12/21 (Sat) MUSE, Kyoto 17:00 / 17:30 ▼2025 02/11 (Tue) Club eX, Tokyo 17:00 / 18:00
youtube
Hikaru 13th Single 「End of line」 MV (Short ver.) ③
Hikaru released a third snippet of her “End of line” music video. You can watch it on Instagram! Also be sure to check out her YouTube Short. The song is featured on her EP “Mask” which is set to be on sale at her solo tour venues.
#kalafina#news#keiko#hikaru#hikei#keiko on instagram#ykl vol 20#Hikaru LIVE TOUR -ROUND-#Hikaru Solo Tour 2024/25#EP Mask#End of line#Youtube
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