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ultimatecutenesspeaks · 1 year

Note

Oh don’t you you two know me UCand UB are officially siblings right guys

*UB whispers something to them, and they seem to understand.*

Himiko: Ohhhh. Yeah, of course.

Gonta: Bunny, UC and UB are great siblings, aren't they?

Himiko: No wonder they were always together.

#himiko speaks🐰#gonta speaks🐰#answered asks🐰💗#bunny anon #persona 3 timeline #time travel arc

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abitterlifethroughcinema · 3 years

Video

@barbaraperezmusic doing straight talk, no bloody chaser, about the oft-time truth & reality of the performing musician 👨‍🎤 Don’t Be Fooled…! The hustle is more than just a #VanMcCoy song, chirren! ✊🏾💥🌍 • • • #BCN #local #ambition #global 🗺#vision #artist #musicians #writers #performers #creators #inspiration #UCanDance 🕺🏽#LookAtYourPants #actors #movers #shakers #quakers #directors #authors #artist #AWARE #SupportLocalCulture #SupportART #others #providence #grooved AND #moved with #LIVE! #English #Radio 📻 🔥 (at RKB Radio Kanal Barcelona 106.9 fm) https://www.instagram.com/p/CQWx9hcKRtw/?utm_medium=tumblr

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tes-trash-blog · 4 years

Text

Nivdohlost (nihv-dohl-ost) noun, slang

Simply put, this backwards compliment means “handsome idiot”. It’s said that Scholar Felaquin fully understood the meaning of nivdohlost after a particularly attractive Nord asked what the Elvish word for Tamriel was.

#falmer word of the week #non canon guide to the falmer tongue #that's right the falmer had a word for himbo #don't worry 'dohlost' has a positive connotation #unlike 'ucand' which also means idiot but uh.. not a nice way of saying it

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rogerioreal · 6 years

Photo

#uCandaNcE (em Clube V.U.)

#ucandance

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healthtimetaylor · 5 years

Text

Astragaloside IV alleviates the symptoms of experimental ulcerative colitis in vitro and in vivo.

PMID: Exp Ther Med. 2019 Oct ;18(4):2877-2884. Epub 2019 Aug 16. PMID: 31572532 Abstract Title: Astragaloside IV alleviates the symptoms of experimental ulcerative colitisand. Abstract: Ulcerative colitis (UC) is a chronic and relapsing inflammatory intestinal disease. Although the morbidity of UC has increased notably in recent years, effective therapeutic treatment remains unsatisfactory. Astragaloside IV (ASI), a monomeric compound isolated from the traditional Chinese medicine herb, exhibits anti-inflammatory effects. The present study aimed to investigate the therapeutic effects of ASI on experimental UCand. Cell proliferation was detected via a Cell Counting Kit-8 assay. In addition, the concentrations of the inflammatory factors myeloperoxidase (MPO), tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), interleukin-6 (IL-6) and nitric oxide (NO) in the colon tissues were determined by ELISA. Western blot analysis was used to examine phosphorylated transcription factor p65 (p-p65), p-inhibitor of NF-κB (IκB), claudin-1 and tight junction protein ZO-1 (ZO-1) protein levelsand, respectively. The results indicated that lipopolysaccharide (LPS) significantly increased the pro-inflammatory cytokines TNF-α, IL-1β and IL-6 in CCD-18Co cells, which was markedly ameliorated by ASI. In addition to the inhibition of pro-inflammatory cytokines, ASI decreased the levels of p-p65 and p-IκB proteins. In addition, ASI decreased the disease activity index scores, and increased colon lengths in dextran sulfate sodium-induced UC mice. ASI also decreased the levels of the pro-inflammatory factors MPO, TNF-α, IL-1β, IL-6 and NO, and upregulated the expression of claudin-1 and ZO-1 in colon tissues. Therefore, ASI was effective in ameliorating experimental UCandvia the inhibition of inflammatory molecules, and the downregulation of NF-κB signaling. In conclusion, ASI may serve as a potential therapeutic agent for the treatment of UC.