#stage iv metastatic breast cancer

[fatedwithmbc]

I never wear heels. Ok, I ALMOST never wear heels, but I did when I went to church on Christmas Eve. The next day my heel felt bruised. I chalked it up to a poor shoe decision and figured it would heal itself as time went on. Here we are a month later and I have finally gone to the Podiatrist. It’s not a bruise: I have Insertional Achilles Tendonitis and a Sural Nerve Impingement. Best case scenario steroids and injections will resolve my issues. Physical Therapy may be an option. Worst case scenario could require surgery. I was informed it’s a major surgery as I have would have to have the piece of bone removed from my heel that is aggravating the Achilles. For the next week I’m on steroids, have stretching to do and had to buy a more flexible sneaker. If there is no improvement, it’s injection time at my next appointment.

Despite this being all foot related, my MBC became forefront of the appointment. As I was having my foot x-rayed, the technician asked if I was pregnant or trying and I said matter of factly I could not conceive. She asked why and we began a discussion about my diagnosis and she couldn’t fathom it because of how young I looked. She seemed genuinely concerned and shocked. She asked about my metastasis and how my treatment was coming along. I felt heard by a stranger. And it felt genuine.

My doctor also asked about my MBC as the steroids will reduce the effectiveness of my aromatase inhibitor, but it’s the most conservative treatment for my foot.

I never thought my foot appointment would have so much to do with my cancer diagnosis and yet nothing to do with it at all. It was an interesting appointment.

I know I haven’t had an entry in quite sometime but the interactions today stuck with me and I felt like I needed to get the out of my head. I’m glad to have this space for these type of scenarios.

[peptide-ltd]

Poziotinib Researches on Cancers

Poziotinib has been investigated in clinical trials for the treatment of various cancers. Some of the specific conditions studied include:

Breast Cancer

Metastatic Breast Cancer

Increased Drug Resistance

Adenocarcinoma of Lung Stage IV

Adenocarcinoma of Lung Stage IIIB

These trials explore the effectiveness of Poziotinib in targeting cancers that overexpress or have mutations in the epidermal growth factor receptors (EGFR), including HER2 and HER4. Its use is particularly focused on cancers with EGFR exon 20 insertion mutations.

What Is Poziotinib Peptide?

Poziotinib peptide is an orally bioavailable, quinazoline-based, small-molecule, irreversible pan-epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity. It inhibits EGFR (HER1 or ErbB1), HER2, HER4, and EGFR mutants, thereby hindering the proliferation of tumor cells that overexpress these receptors. EGFRs, which are cell surface receptor tyrosine kinases, are frequently upregulated in various cancer cell types and play crucial roles in cellular proliferation and survival.

Poziotinib has been investigated in clinical trials for the treatment of various cancers, including breast cancer, metastatic breast cancer, increased drug resistance, adenocarcinoma of the lung (Stage IV and Stage IIIB), among others. 

For your safety, please buy and use Poziotinib with caution.

What Benefits Can You Get From Poziotinib on NSCLC?

The antitumor activity of poziotinib was found to be significant in patients with EGFR exon 20 positive non–small cell lung cancer (NSCLC). The efficacy of the treatment was found to be highly dependent on the location of the exon 20 loop insertion. These findings were published in Cancer Cell. The results were published in Cancer Cell.

The study, designated as phase 2 (NCT03066206), included 50 patients with advanced non-small cell lung cancer (NSCLC) who exhibited point mutations or insertions in the EGFR exon 20. The study achieved its primary end point with a confirmed objective response rate (ORR) of 32% (95% CI, 20.7%-45.8%) and 31% (95% CI, 19.1%-46%) by investigator and blinded independent review, respectively.

Moreover, researchers found a median progression-free survival (PFS) of 5.5 months (95% CI, 5.4-10.4) with a PFS rate of 43% (95% CI, 30%-60%) at 6 months, and 29% (95% CI, 18%-46%) at 12 months. Median overall survival also appeared to be beneficial at 19.2 months (95% CI, 11.8-24.1) with a disease control rate of 84% (95% CI, 71.5%-92%).

“EGFR exon 20 mutant lung cancers typically don’t respond well to the types of tyrosine kinase inhibitors that have been largely successful in targeting classical EGFR mutations, leaving this patient population with few effective treatment options,” said senior author of the study, John Heymach, MD, PhD, chair of the Thoracic/Head & Neck Medical Oncology at the MD Anderson Cancer Center, in a press release.2 “Our study gives hope for not only a potentially beneficial treatment option, but for a new level of precision to better target EGFR exon 20 mutations and to design more effective clinical trials.”

A new drug application for poziotinib was accepted by the FDA for patients with advanced or metastatic NSCLC harboring HER2 exon 20 insertion mutations in February 2022. Poziotinib also received fast track designation from the FDA in March 2021 for patients with HER2 exon 20 insertion–mutated NSCLC.

[diseaseinfohub]

Metastatic breast cancer, also known as stage IV breast cancer, is an advanced form of breast cancer that has spread from the breast to other parts of the body. The symptoms of metastatic breast cancer can vary depending on the organs or areas affected by the spread of cancer cells. Common symptoms may include persistent and unexplained bone pain, shortness of breath, coughing, headaches, weakness, unintentional weight loss, and jaundice. In some cases, individuals may also experience swelling in the lymph nodes or other areas where the cancer has spread. It's crucial for individuals with a history of breast cancer to stay vigilant for any new or worsening symptoms and promptly seek medical attention for early detection and appropriate management.

[suchananewsblog]

How to Find Support and Community for Advanced Breast Cancer

When Sandy Cassanelli of Glastonbury, CT, was diagnosed with stage IV breast cancer 8 years ago, her first phone call was to the one person she knew would understand: a close friend who also had metastatic breast cancer.  “She answered all of my questions and gave me hope,” says Cassanelli, who’s now 47. “She was the only woman I knew who had metastatic disease. If I hadn’t reached out to her…

[konner512]

My mom was diagnosed with Stage IV metastatic breast cancer in 2017. She has been working full time as a teacher while also undergoing multiple treatments. Unfortunately there is no cure for her type of cancer and her health has gradually gotten worse over the years. She is now at the point with chemo and radiation that most of her PTO days have been used and it’s been getting harder to go to work everyday.  Therefore, we are reaching out to our community of friends and family in hopes of receiving support for her and her quality of life. Funds would be used for medical bills and necessities. As a teacher she has helped children grow and learn over the past 20 years.  We would be eternally grateful for any support you can provide! :) thank you for even considering helping out. 

[shannendoherty-fans]

Shannen Doherty’s Close Friend and Doctor Describes Her 'Beautiful and Loving' Final Moments (Exclusive)

"She wasn't ready to leave because she loved life," Dr. Lawrence D. Piro tells PEOPLE of the actress, who died on July 13 after living with stage 4 breast cancer

By Dana Rose Falcone Updated on July 16, 2024 10:09AM EDT

Actress Shannen Doherty died on Saturday, July 13, after fighting stage 4 breast cancer

The Charmed alum found a friend in her oncologist Dr. Lawrence D. Piro, and he was by her bedside when she died

Piro calls Doherty "an incredible warrior" to PEOPLE and says "things turned much more difficult in the last couple of weeks" when it came to her health

Shannen Doherty considered her oncologist Dr. Lawrence D. Piro not only a trusted adviser during her breast cancer journey, but also a close friend.

“We both immediately got each other,” Piro, the President and CEO of Cedars-Sinai affiliate The Angeles Clinic and Research Institute in Los Angeles, tells PEOPLE. “Sometimes that just happens. The vibe is right and you understand each other and you understand what the thoughts mean as if you had known each other for years before that meeting. That's what it was like for us when we first met, and it was that way all the way until the very last.”

Doherty, who died on Saturday, July 13, at age 53, previously stated that she and Piro had “a great relationship, one of mutual respect.”

“The key is to find a doctor who listens to you and appreciates your concerns,” she wrote on Instagram in September 2016. “Not every cancer patient is the same. Also, it took me a lot of meetings to find my dream team. Don't settle.”

The Charmed star first received her breast cancer diagnosis in 2015 and went into remission in 2017. The cancer returned in 2019, and Doherty revealed in 2020 that she’d been diagnosed with metastatic stage 4 cancer.

Piro, who appeared on the Jan. 1 episode of Doherty's podcast, Let's Be Clear, remembers the actress as “a very intelligent person” who “was a very active participant in her entire health journey.”

“Whenever she learned some new fact or some new idea in her medical journey, she would immediately call me or forward something to me and we would discuss it and see whether it had any relevance to her scenario and where it would fit into the scheme of things for her,” he recalls. “I was always amazed with the way in which she could separate her own emotions about being so young and being on such a difficult journey from the fact-finding part. She was so razor focused and level-headed about those things.”

According to Piro, Doherty was “a step above positive” when it came to how she viewed her prognosis.

“In her mind, she was not wanting to consider any other alternative than ‘we were beating this and we were engaged in life,’” Piro says. “We didn't really talk about what that meant in terms of additional time for her because that just wasn't how she operated. She wanted to live every day, not as if it were her last day, but as if it were the beginning of a whole another chapter for her.”

The actress said on the June 24 of her Let’s Be Clear with Shannen Doherty podcast that she planned to start chemotherapy again in hopes of beating her stage IV breast cancer that spread to her bones last year.   “We kept going until we couldn't go any more,” Piro says. “The last conversation that we had, she was in the process of realizing that things had taken a pretty significant turn. The conversation was about love and support and caring and still fighting through. She wanted to continue to take treatment and fight through, even though her physical condition had taken a bit of a downturn. And so we did.”

The doctor explains that Doherty found herself with “a limited situation of options” due to “her condition” over the last few weeks. “But still, the conversation was about, ‘What can we do within those limitations?’ as opposed to, ‘Let's do nothing,'" he says. "That wasn't even open for discussion, because that's not how Shannen lived. She was an incredible warrior in everything she did.”

In the face of declining health, the Beverly Hills, 90210 alum had also been involved in stressful divorce proceedings with her ex-husband Kurt Iswarienko, who she filed for divorce from in April 2023 after 11 years of marriage.

But, “I never got the sense that that emotional challenge was draining her ability to continue to fight on the medical side,” Piro says. “It certainly made it more challenging, but she's such a winner that I feel like she pulled all the resources necessary to give the best fight against cancer, even though she was being very emotionally challenged. She fought so hard and she didn't believe that it would ever be over, which kind of makes everybody around you believe that, too, because you want to believe that.”

However, it quickly became evident that that wouldn’t be the case. “Things turned much more difficult in the last couple of weeks, and that's when it became clear that it was heading in a different direction,” Piro says. “We continued to fight while putting in more support and we just kept loving and hoping and supporting.”

Piro spent Doherty’s final moments with her and some of her love ones, including her dog Bowie.

“In the last few hours, she was in a place where she was very comfortable and sleeping and transitioning, and she was surrounded by some of her very close friends,” he shares. "The room was surrounded by a select group of friends that were giving her a lot of care and support. It was somber and sad, but beautiful and loving. The hardest thing about this was that she wasn't ready to leave because she loved life.”

Piro typically associates Doherty’s home with vibrant dinner parties. “She was an incredible, incredible chef,” the medical expert says. “It was very strange being in her home with her in a bed and not in the kitchen bringing out pizzas and cooking pasta. She loved cooking, she loved giving parties. She loved entertaining. What kept her going was a love for life and a desire to have more life. That was incredibly painful for her not to be able to do that.”

Piro believes Doherty’s legacy should be one of treating others with kindness.

 “This tremendous love for life was inspired by a love for people and a love for being treated well,” he says. “And I think that that grew out of being in public eye from a very young age and feeling misunderstood most of her life. She would want us to live our lives as strongly as we can, committed to our convictions and to not allow others to label you or to misrepresent you and stop you from living your best life.”

For more on Shannen Doherty, pick up this week's issue of PEOPLE, on newsstands Friday.

[james-p-sullivan]

.

ive spent the entire day in tears, my moms diagnosis is basically the absolute worst case scenario. we originally thought it was just stage 1 lunch cancer and that it’d be an easy surgery to go in there and cut it out but it turns out it was actually metastatic breast cancer in the lining of her lungs and heart.

she’s been through chemo and radiation before, i have no idea what it means when a cancer recurs a decade after she beat it the first time. and it’s on her heart and lungs, it’s not like she can go without either.

she’s been taking about her possibly not being here for long and it just breaks my heart to think about. my dad died of cancer a few years back and it hurts so much to think my mom would be leaving so soon. she’s had such a hard life and this would be such a cruel time for her to go.

anyway im crying and i really don’t know what to do anymore. i cant lose my mom

[drrajinderkaursaggu]

Who Is the Leading Breast Cancer Surgeon in Indirapuram?

A breast cancer surgeon in Indirapuram specializes in diagnosing, treating, and surgically managing breast cancer. These experts perform procedures such as lumpectomies, mastectomies, and breast reconstruction, customizing treatments to each patient’s unique condition. Working alongside a multidisciplinary team of oncologists, radiologists, and pathologists, these surgeons ensure a comprehensive approach to addressing both the medical and emotional aspects of breast cancer.

Patients consulting breast cancer surgeons in Indirapuram receive personalized care starting with an in-depth consultation. Surgeons in this region are proficient in advanced minimally invasive and reconstructive techniques, which optimize recovery and aesthetic results. They prioritize patient education, ensuring individuals feel informed and confident throughout their treatment journey. Equipped with modern facilities and cutting-edge technology, these specialists provide compassionate and high-quality care.

Breast Cancer Stages Overview Breast cancer is categorized into five stages, guiding the treatment plan:

Stage 0 (Carcinoma in Situ): Non-invasive stage where abnormal cells remain confined to milk ducts or lobules.

Stage I: Early invasive cancer; the tumor measures up to 2 cm and may involve lymph nodes.

Stage II: Tumors measure 2–5 cm, potentially spreading to nearby lymph nodes.

Stage III: Advanced local stage with larger tumors or extensive lymph node involvement.

Stage IV: Metastatic cancer, where cancer has spread to distant organs like bones or lungs.

Expert Recommendations from Dr. Rajinder Kaur Saggu Dr. Rajinder Kaur Saggu, a renowned breast cancer surgeon in Indirapuram, highlights the importance of early detection through regular screenings and self-examinations. She emphasizes maintaining a healthy lifestyle by limiting alcohol, exercising regularly, and addressing family history-related risks. Early diagnosis enhances treatment success, and Dr. Saggu offers personalized guidance to help patients manage risk factors effectively.

For more details on breast cancer care, visit Dr. Rajinder Kaur Saggu's YouTube channel, Breast Health by Dr. R.K. Saggu, for insights on awareness, early detection, and treatment options.

Clinic Location and Directions

Clinic Address:37/3, Ground Floor, East Patel Nagar, New Delhi, Delhi 110008

Easy Directions to Reach the Clinic:

From the Western Line:

Board a train to New Delhi Railway Station via the Western Line.

From the station, take a direct metro to Rajendra Place Metro Station (Blue Line).

The clinic is a short 5-minute walk or a quick rickshaw ride from the metro station.

From the Central Line:

Travel to New Delhi Railway Station via the Central Line.

Switch to the Blue Line Metro and alight at Rajendra Place Metro Station.

Walk or take a rickshaw to reach the clinic within 5 minutes.

For Patients Outside Mumbai:

By Air: Fly to Indira Gandhi International Airport in New Delhi. From the airport, take a cab or the Airport Metro Express to New Delhi Metro Station. Then switch to the Blue Line Metro and alight at Rajendra Place Metro Station.

By Train: Arrive at New Delhi Railway Station and follow the steps above to reach the clinic via the Blue Line Metro.

For further assistance or detailed directions, feel free to contact the clinic directly!

[manipalhospital1]

How to Recognise the Signs of Breast Cancer: Quick Guide

Early detection is pivotal in Breast Cancer management. Many women experience or get awareness of a lump in their breast during routine activities such as bathing or even dressing up. Knowledge of what your breasts normally look and feel like can help detect unusual lumps, which may be the first sign of breast cancer. This ensures early detection and thus early treatment of Breast Cancer.

Synopsis

 Signs and symptoms of breast cancer: What not to ignore

 How to perform a breast self-exam?

 Stages of Breast Cancer

 Types of Breast Cancer

 Genetic Testing and Counseling

 The Importance of Regular Screenings and Mammograms

 Lifestyle Changes to Lower Breast Cancer Risk

 What are the treatment options for breast cancer?

 Conclusion

 

Signs and symptoms of breast cancer: What not to ignore

The most common sign of breast cancer is the presence of a lump inside the breast. However, other symptoms and signs of breast cancer in women draw your attention, including:

Modifications to the breast’s size or shape. Any noticeable change in the size or shape of the breast should be checked by a healthcare professional.

Puckering or dimpling of the breast tissue. This can indicate changes beneath the skin that need medical evaluation.

Nipple inversion. If the nipple starts to turn inward, it could be a sign of breast cancer.

Swelling in your lymph nodes armpit. Swollen lymph nodes can be an early sign of breast cancer spreading.

Redness of skin. Red or discoloured skin on the breast can be a symptom of inflammatory breast cancer.

Bloody discharge from your nipple. Any unusual discharge, especially if it is bloody, should be investigated.

Pain in the breast or underarm area. Persistent pain in these areas should not be ignored.

It is, however, vital to note that none of these indicators and manifestations point toward a diagnosis of cancer of the breast. However, if you do notice any of these changes, it would be very advisable to have a medical opinion from your doctor.

How to perform a breast self-exam?

Breast self-examination is a simple practice that enables one to notice the changes in breast tissue as early as possible. Breast self-examinations should always be done monthly.

Follow these methods to self-examine your breast:

Place your arm beneath your head while lying on your back. This position spreads the breast tissue evenly over the chest wall, making it easier to feel.

Use your fingers to gently feel your breast. Use the pads of your fingers to press down with light, medium, and firm pressure.

Examine for any irregularities, elevations, or alterations. Move in a circular pattern from the outside to the centre of the breast.

Repeat the process on the opposite breast. Ensure both breasts are checked thoroughly.

Observe your breast changes by looking at the mirror. Look for any visible changes in size, shape, or skin texture.

Lift your arms above your head and look for any differences. This can help reveal changes that might not be noticeable otherwise.

Stages of Breast Cancer

Breast cancer is classified into stages from 0 to IV, based on the size of the tumour, lymph node involvement, and whether the cancer has spread to other parts of the body.

Stage 0: Known as ductal carcinoma in situ (DCIS), this stage is non-invasive, meaning the cancer cells are confined to the ducts of the breast and have not spread to surrounding tissue.

Stage I: Early-stage invasive breast cancer where the tumour is small and has only begun to invade nearby breast tissue.

Stage II: The cancer is larger and/or has spread to a few nearby lymph nodes.

Stage III: Locally advanced cancer that is larger and has spread to several lymph nodes or nearby tissues.

Stage IV: Metastatic breast cancer where the cancer has spread beyond the breast and nearby lymph nodes to other parts of the body.

Types of Breast Cancer

Breast cancer can be categorized into several types based on where it begins and its characteristics:

Ductal Carcinoma In Situ (DCIS): A non-invasive cancer where abnormal cells are found in the lining of a breast duct but have not spread outside the duct.

Characteristics: Considered the earliest form of breast cancer, highly treatable.

Invasive Ductal Carcinoma (IDC): The most common type of breast cancer, starting in the milk ducts and then invading nearby tissue.

Characteristics: Can spread to other parts of the body through the lymphatic system and bloodstream.

Triple-Negative Breast Cancer: A type of breast cancer that does not have receptors for estrogen, progesterone, or HER2.

Characteristics: More aggressive and difficult to treat, often requiring chemotherapy.

HER2-Positive Breast Cancer: Cancer cells that have higher levels of the HER2 protein, which promotes the growth of cancer cells.

Characteristics: Tends to grow and spread faster but can be treated with targeted therapies.

Genetic Testing and Counseling

Genetic testing plays a crucial role in assessing the risk of breast cancer, especially for individuals with a family history of the disease. Testing for mutations in genes like BRCA1 and BRCA2 can provide valuable information.

BRCA1 and BRCA2 Genes: Mutations in these genes significantly increase the risk of breast and ovarian cancers.

Testing: Involves a blood or saliva sample to check for genetic mutations.

Counselling: Genetic counsellors help interpret test results and guide patients on preventive measures, such as increased surveillance, lifestyle changes, or preventive surgeries.

The Importance of Regular Screenings and Mammograms

Regular screenings and mammograms are vital for early detection of breast cancer, which can significantly improve treatment outcomes.

Mammograms: X-ray images of the breast that can detect tumours that are too small to be felt.

Benefits: Can detect breast cancer early, often before symptoms develop.

Frequency: Recommended annually for women aged 40 and older, or earlier for those at high risk.

Clinical Breast Exams: Performed by healthcare professionals to check for lumps or other changes.

Benefits: Complements mammograms and helps detect abnormalities.

Other Imaging Tools: Ultrasound and MRI can be used for further evaluation of suspicious areas found on mammograms or in women with dense breast tissue.

Lifestyle Changes to Lower Breast Cancer Risk

Adopting healthy lifestyle habits can help reduce the risk of breast cancer. Here are some actionable modifications supported by research:

Diet: A diet rich in fruits, vegetables, whole grains, and lean proteins can help maintain a healthy weight and reduce cancer risk.

Exercise: Regular physical activity helps maintain a healthy weight and reduces the risk of breast cancer.

Weight Management: Maintaining a healthy weight is crucial, especially after menopause, as obesity increases the risk of breast cancer.

Limiting Alcohol: Alcohol consumption is linked to an increased risk of breast cancer.

Not Smoking: Smoking is linked to many types of cancer, including breast cancer.

By incorporating these lifestyle changes, individuals can take proactive steps to lower their risk of breast cancer and improve their overall health.

What are the treatment options for breast cancer?

Treatment for breast cancer depends upon the staging of the cancer and the general condition of the patient. Here are the detailed descriptions of the treatment options:

Surgical Intervention

Surgical intervention is often the first line of treatment for breast cancer. The goal is to remove the tumour and some surrounding tissue to ensure all cancerous cells are eliminated. There are several types of surgical procedures:

Lumpectomy: This procedure involves removing the tumour and a small margin of surrounding tissue. It is often referred to as breast-conserving surgery because most of the breast remains intact.

Benefits: Preserves most of the breast, shorter recovery time.

Side Effects: Pain, swelling, tenderness, and changes in the shape of the breast.

Outcomes: Effective for early-stage cancers, often followed by radiation therapy to reduce the risk of recurrence.

Mastectomy: This involves removing the entire breast. There are different types of mastectomies, such as total mastectomy (removal of the whole breast) and modified radical mastectomy (removal of the breast along with some lymph nodes).

Benefits: Reduces the risk of cancer recurrence, especially in high-risk patients.

Side Effects: Pain, swelling, risk of infection, and emotional impact due to loss of the breast.

Outcomes: Effective for larger or more advanced cancers, may be followed by reconstruction surgery.

Axillary Lymph Node Dissection: This procedure involves removing lymph nodes from the armpit area to check for the spread of cancer.

Benefits: Helps determine the stage of cancer and plan further treatment.

Side Effects: Risk of lymphedema (swelling due to lymph fluid), pain, and limited arm movement.

Outcomes: Provides important staging information, and can guide additional treatments.

Radiation Therapy

Radiation therapy uses high-energy X-rays to target and destroy cancerous cells. It is often used after surgery to eliminate any remaining cancer cells.

Benefits: Reduces the risk of cancer recurrence, and can be targeted to specific areas.

Side Effects: Skin irritation, fatigue, swelling, and changes in breast texture.

Outcomes: Highly effective in reducing recurrence rates, especially after breast-conserving surgery.

Chemotherapy

Chemotherapy involves the use of drugs to destroy cancerous cells. It can be administered before surgery (neoadjuvant chemotherapy) to shrink tumours or after surgery (adjuvant chemotherapy) to kill any remaining cancer cells.

Benefits: Can shrink tumours before surgery, reduce the risk of recurrence, and treat cancer that has spread.

Side Effects: Nausea, hair loss, fatigue, increased risk of infection, and other systemic effects.

Outcomes: Effective for various stages of breast cancer, improves survival rates, but requires careful management of side effects.

Hormone Therapy

Hormone therapy is used to stop hormones like estrogen from binding with breast cancer cells. It is effective for hormone receptor-positive cancers.

Benefits: Reduces the risk of cancer recurrence, and can be used long-term.

Side Effects: Hot flashes, fatigue, mood swings, and risk of blood clots.

Outcomes: Effective in reducing recurrence for hormone receptor-positive cancers, often used for several years after initial treatment.

Targeted Therapy

Targeted therapy involves the use of drugs that specifically target molecules involved in the growth and survival of cancer cells. These therapies can be more effective and less harmful to normal cells.

Benefits: Targets specific cancer cells, fewer side effects compared to chemotherapy.

Side Effects: Diarrhea, liver problems, skin rashes, and fatigue.

Outcomes: Effective for cancers with specific genetic markers, such as HER2-positive breast cancer, improves survival rates and quality of life.

This blog tries to outline, at least briefly, the methods of identifying some symptoms and signs of breast cancer. It shall also explore the importance of early detection and diagnosis alongside discussing the treatment options available.

Conclusion

Remember that early detection is your best defence against breast cancer. If you observe changes in your breasts or any signs of breast cancer, do not hesitate to seek medical advice. Early detection of breast cancer can increase the chances of successful treatment and recovery.

At Manipal Hospitals Delhi, the best cancer treatment hospital in Delhi, we are committed to providing a comprehensive range of breast care services. Our team, consisting of experienced oncologists and surgeons, is committed to providing the most advanced treatments and support for patients suffering from breast cancer.

Visit us for breast cancer treatment in Delhi and start your road to healthy living.

Keep on stunned with us for more such health-related information.

[nohalfmeasuresamj]

Scans #3 on Enhertu

As most of you are aware, the treatment for Stage IV Metastatic Breast Cancer (MBC) doesn’t end while we are still alive (with a few notable exceptions that we hope will become the rule). To determine whether treatment is working, those of us living with MBC undergo scans in various intervals (usually 3, 6, or 12 months) and if we are able to ignore or look away from cancer on a daily basis, it…

[gynecologistindore]

Breast Cancer: Understanding the Basics of Diagnosis and Treatment

Breast cancer is one of the most commonly diagnosed cancers worldwide, affecting millions of women and, although less commonly, men each year. The importance of early detection and effective treatment cannot be overstated, as they are crucial for improving survival rates and quality of life. In this article, we will explore the basics of breast cancer, including how it is diagnosed, the various stages of the disease, and the treatment options available.

Diagnosis of Breast Cancer

The first step in diagnosing breast cancer is identifying symptoms. Many women discover the presence of a lump or abnormality in their breast through self-exams or a routine screening. However, not all lumps are cancerous; some may be benign conditions like cysts or fibroadenomas. For this reason, obstetrician and genecology in Indore often recommend regular screenings, especially for women over the age of 40 or those with a family history of breast cancer.

If a lump is detected, the next step is to confirm whether it is malignant. This is typically done through imaging techniques like mammograms, ultrasound, or MRI. A biopsy may be performed to collect tissue samples, which are then examined under a microscope to determine the presence of cancer cells. These diagnostic tests are critical in determining the type, size, and stage of the cancer, which helps guide the treatment plan. Early detection through these methods significantly improves the chances of successful treatment and recovery.

Staging and Types of Breast Cancer

Once breast cancer is confirmed, it is classified according to its stage, which reflects how far the cancer has spread. The stages range from 0 (non-invasive or localized cancer) to stage IV (advanced cancer that has spread to other organs). Staging helps doctors plan the most appropriate course of treatment and provides an understanding of the cancer's progression.

Breast cancer is also categorized by its cellular characteristics. The two most common types are invasive ductal carcinoma (IDC) and invasive lobular carcinoma (ILC), though there are other subtypes. IDC, the most common form, begins in the milk ducts and can spread to surrounding tissue. ILC starts in the milk-producing glands and is less common.

In addition to the type of cancer, the tumor's hormone receptor status (estrogen and progesterone receptors) and HER2 status (a gene that promotes cancer cell growth) also play a significant role in determining treatment options. These molecular markers help oncologists choose therapies that are more likely to be effective in targeting the cancer cells.

Treatment Options for Breast Cancer

The treatment of breast cancer depends on several factors, including the stage and type of cancer, as well as the patient's overall health and preferences. Common treatment modalities include surgery, radiation therapy, chemotherapy, hormone therapy, and targeted therapies. Often, a combination of these treatments is used to increase the likelihood of successful outcomes.

Surgical options are typically the first line of treatment for breast cancer. The type of surgery depends on the size and location of the tumor. A lumpectomy involves removing the tumor along with a small margin of surrounding tissue, while a mastectomy involves the removal of the entire breast. In some cases, lymph nodes in the underarm area may also be removed to check for cancer spread.

After surgery, radiation therapy may be used to destroy any remaining cancer cells in the breast or surrounding areas. This is commonly recommended for women who undergo lumpectomy and for those whose cancer has spread to lymph nodes. Chemotherapy, which uses drugs to kill cancer cells, may be administered before or after surgery, depending on the tumor’s size, grade, and other factors. Chemotherapy can also be used to treat metastatic breast cancer, which has spread to other parts of the body.

For hormone receptor-positive breast cancer, hormone therapy is often used to block the body's hormones from fueling cancer growth. This can be done through medications like tamoxifen or aromatase inhibitors, which either block estrogen or lower its levels in the body. Targeted therapies, such as monoclonal antibodies, can be used to specifically target cancer cells without affecting healthy tissue. These therapies are often used in combination with other treatments, especially for HER2-positive breast cancer.

Role of a Gynecologist in Breast Cancer Care

Gynecologists play a crucial role in the early detection and management of breast cancer, especially in Indore. While gynecologists primarily focus on women’s reproductive health, they are also trained to perform routine breast exams and provide important guidance on breast health and self-examination. Many gynecologists in Indore work closely with oncologists and other specialists, ensuring that women receive comprehensive care tailored to their specific needs. Through regular check-ups, gynecologists help women stay informed about the importance of early detection, advise on risk-reducing lifestyle changes, and make necessary referrals for advanced screenings or treatment. Their collaborative approach is key to improving outcomes and offering ongoing support to those facing breast cancer.

Breast cancer diagnosis and treatment are complex processes that require collaboration between various healthcare providers. Understanding the basics of breast cancer—its diagnosis, staging, and treatment options—can help patients make informed decisions and take an active role in their health. Regular screenings, self-exams, and a close relationship with your healthcare team, including obstetricians, gynecologists, and oncologists, can make all the difference in early detection and treatment success.

[fatedwithmbc]

Also, apparently 6/4 is Cancer Survivors Day-

And in the community survivor means whatever phase of the journey you are in.

Technically, I would have never considered being in active treatment as “surviving”; but many in the cancer community do.

Happy Belated Cancer Survivors Day to me, Brittany and the community! 💗

[bcisurat]

Breaking Down the Stages of Breast Cancer: A Comprehensive Guide

Breast cancer remains one of the most common cancers affecting women worldwide. Understanding its stages is crucial for patients, families, and healthcare providers. These stages indicate the extent of cancer in the body, guiding treatment options and predicting outcomes. In this comprehensive guide, experts from Blood and Cancer Institute, known for housing some of the best breast cancer specialists in Surat, break down each stage, providing clarity and insight into this complex disease.

Stage 0: Non-Invasive Breast Cancer

Stage 0 breast cancer, also known as carcinoma in situ, is the earliest form of breast cancer. At this stage, cancer cells are confined to the ducts or lobules of the breast and have not invaded surrounding tissues. There are two main types of non-invasive breast cancer:

1. Ductal Carcinoma In Situ (DCIS): Cancer cells are found in the lining of the breast ducts but have not spread.

2. Lobular Carcinoma In Situ (LCIS): Abnormal cells are found in the lobules but have not spread. LCIS is considered a marker for increased breast cancer risk rather than a true cancer.

At this stage, cancer specialists in Surat prefer treatment options which include surgery (lumpectomy or mastectomy) and radiation therapy. Hormonal therapy may also be recommended to reduce the risk of recurrence.

Stage I: Early Invasive Breast Cancer

Stage I breast cancer is the earliest stage of invasive breast cancer, where cancer cells have begun to invade neighbouring breast tissue. This stage is further divided into two subcategories:

- Stage IA: The tumour measures up to 2 centimetres (cm) and has not spread to the lymph nodes.

- Stage IB: Small clusters of cancer cells (0.2 to 2 millimetres) are found in the lymph nodes, or a tumour in the breast measures 2 cm or less and has spread to the lymph nodes.

As advised by the cancer specialist in Surat, the treatment for stage I involves a combination of surgery, radiation therapy, chemotherapy, and/or hormonal therapy, depending on the specific characteristics of the tumour.

Stage II: Localized Advanced Breast Cancer

Stage II breast cancer signifies a larger tumour or greater spread within the breast or nearby lymph nodes. It is divided into two subcategories:

- Stage IIA: The tumour is either larger than 2 cm but less than 5 cm, or it has spread to 1–3 nearby lymph nodes. Alternatively, there is no tumour in the breast, but cancer is found in 1–3 lymph nodes.

- Stage IIB: The tumour is larger than 2 cm but not more than 5 cm and has spread to 1–3 lymph nodes, or the tumour is larger than 5 cm but has not spread to the lymph nodes.

Treatment for stage II breast cancer often includes surgery (lumpectomy or mastectomy), radiation therapy, chemotherapy, and hormonal therapy. Targeted therapy may also be used for certain types of breast cancer.

Stage III: Regional Advanced Breast Cancer

Stage III breast cancer, also known as locally advanced breast cancer, indicates more extensive disease that has not spread to distant parts of the body. It is divided into three subcategories:

- Stage IIIA: The tumour may be any size and has spread to 4–9 lymph nodes, or it is larger than 5 cm and has spread to 1–3 lymph nodes.

- Stage IIIB: The tumour has spread to the chest wall or skin and may involve up to 9 lymph nodes. This stage includes inflammatory breast cancer, a rare and aggressive form.

- Stage IIIC: The cancer has spread to 10 or more lymph nodes, including those above or below the collarbone, or to lymph nodes near the breastbone.

Treatment for stage III breast cancer is typically aggressive and may include surgery, radiation therapy, chemotherapy, hormonal therapy, and targeted therapy. Neoadjuvant therapy (treatment given before surgery) is often used to shrink the tumour and make it easier to remove.

Stage IV: Metastatic Breast Cancer

As explained by our breast cancer specialist in Surat at BCI- Blood and Cancer Institute, Stage IV breast cancer, or metastatic breast cancer, indicates that cancer has spread to distant parts of the body, such as the bones, liver, lungs, or brain. This stage is the most advanced and is considered incurable. However, treatments can help manage the disease and improve quality of life.

Cancer treatment in Surat for stage IV breast cancer focuses on controlling the spread of cancer and alleviating symptoms. Options include systemic therapies such as chemotherapy, hormonal therapy, targeted therapy, and immunotherapy. Radiation therapy and surgery may also be used to relieve symptoms and manage complications.

Understanding the Importance of Staging

The stage of breast cancer at diagnosis plays a critical role in determining the appropriate treatment plan and prognosis. Early detection and accurate staging are essential for improving outcomes. Regular screenings, such as mammograms, and being aware of breast cancer symptoms can lead to earlier diagnosis and more effective treatment.

Conclusion

Breaking down the stages of breast cancer provides a clearer understanding of the disease’s progression and the importance of timely and appropriate treatment. From the non-invasive stage 0 to the advanced stage IV, each stage presents unique challenges and requires tailored treatment strategies. We at BCI- Blood and Cancer Institute advocates that by staying informed and proactive, individuals can navigate their breast cancer journey with greater confidence and hope.

[konner512]

https://gofund.me/3ea189da

My mom was diagnosed with Stage IV metastatic breast cancer in 2017. She has been working full time as a teacher while also undergoing multiple treatments. Unfortunately there is no cure for her type of cancer and her health has gradually gotten worse over the years. She is now at the point with chemo and radiation that most of her PTO days have been used and it’s been getting harder to go to work everyday. Therefore, we are reaching out to our community of friends and family in hopes of receiving support for her and her quality of life. Funds would be used for medical bills and necessities. As a teacher she has helped children grow and learn over the past 20 years. We would be eternally grateful for any support you can provide! :) thank you for even considering helping out.

[joie6000]

2024 has been a year and we are only 19 days in.

Patrick’s mom, who was diagnosed with stage IV bladder cancer a mere two months ago, has had to stop chemo for good. It’s not working. The tumors keep growing and a 9 centimeter one is now sitting on her lung.

I saw one of my friends at the grocery store, whose husband has stage IV cancer, and she said, “look at you making cookies for the volleyball team” given that she saw my cart full of baking supplies. I looked at her and said, “these cookies are for my in-laws.” My eyes filled with tears and she knew right then and there it wasn’t good. I said, “I’m so sorry but I just need to go.” She gets it. She lives this every day. She’s incredibly strong.

She just texted me how sorry she is and I wrote back how sorry I am for them. We are waiting on a liver for her husband and my god it needs to come soon.

Another parent friend is dying of metastatic breast cancer. 10 years she’s fought. She has young girls.

Patrick lost his job. Well back in July he found out that his group was massively downsizing. His last day is in March. He’s interviewing a ton and getting so many good leads. But then he feels conflicted not being with his mom, who most likely only has months to live.

Today I told the kids that life isn’t always fair. And sometimes it seems downright cruel. And that they need to add a few more requests during special intentions at prayer time.

It’s a lot but we keep going but a vacation from all of this sure sounds nice.

[drrajinderkaursaggu]

Who is the Best Breast Cancer Surgeon in Indirapuram?

A breast cancer surgeon in Indirapuram specializes in the diagnosis, treatment, and surgical care of breast cancer patients. These surgeons are trained to perform a variety of procedures, including lumpectomies, mastectomies, and breast reconstruction surgeries, tailored to each patient’s unique needs. Breast cancer surgeons in Indirapuram work with a multidisciplinary team, which often includes oncologists, radiologists, pathologists, and support staff, to create a comprehensive treatment plan that addresses both medical and emotional aspects of breast cancer.

Patients seeking breast cancer surgeons in Indirapuram can expect personalized care, beginning with a thorough consultation to discuss their diagnosis, treatment options, and anticipated outcomes. Many of these surgeons have advanced expertise in minimally invasive and reconstructive techniques, enhancing recovery times and aesthetic outcomes. Additionally, leading breast cancer surgeons in this area prioritize patient education and support, ensuring patients are informed and comfortable with every aspect of their care. With access to modern medical facilities and advanced technology, breast cancer surgeons in Indirapuram provide high-quality, compassionate care that helps patients navigate their journey with confidence and hope.

Breast cancer is generally categorized into five main stages, ranging from 0 to IV. Here’s a brief overview of each stage:

Stage 0 (Carcinoma in Situ): This is a non-invasive stage where abnormal cells are found only in the milk ducts or lobules and haven't spread. It includes conditions like ductal carcinoma in situ (DCIS).

Stage I: Early-stage invasive cancer. The tumor is up to 2 cm, and cancer cells may or may not have spread to nearby lymph nodes.

Stage II: In this stage, the tumor is larger (2–5 cm) and may have spread to nearby lymph nodes, or a smaller tumor might have spread to a few lymph nodes.

Stage III: This is an advanced local stage where the tumor is larger than 5 cm or has spread extensively to lymph nodes and nearby tissues but hasn't spread to distant organs.

Stage IV: Known as metastatic or advanced breast cancer, this stage indicates that cancer has spread to distant parts of the body like the bones, liver, or lungs.

Breast cancer surgeons in Indirapuram develop treatment plans based on the stage and specific circumstances of each patient to achieve the best possible outcomes.

Dr. Rajinder Kaur Saggu, a breast cancer surgeon in Indirapuram, emphasizes regular screenings, self-examinations, and maintaining a healthy lifestyle to reduce breast cancer risk. She advises limiting alcohol intake, exercising, and considering family history when planning screenings. Additionally, she highlights the importance of early detection for better treatment outcomes and offers guidance on managing risk factors through lifestyle adjustments. For personalized care and a detailed list of precautions, visit her site here.

For more information on breast cancer treatment and care with Dr. Rajinder Kaur Saggu in Indirapuram, you can visit her YouTube channel: Breast Health by Dr. R.K. Saggu. The channel provides insights on breast cancer awareness, early detection, treatment options, and patient care.

The clinic for Dr. Rajinder Kaur Saggu is located in Indirapuram; you can find directions here: Google Maps.

Reaching the Clinic

From Delhi/NCR: Use the Metro (Indirapuram Metro Station on the Blue Line) or local taxis.

From Outside Mumbai (e.g., New Delhi):

Air Travel: Fly to Indira Gandhi International Airport, then take a cab or metro to Indirapuram.

Train: Arrive at New Delhi Railway Station, then transfer by Metro or taxi to Indrapuram.