#rhabdomyosarcoma

[sideshow-tornado]

This is my niece Ava 😍🥹 She is sixteen years old. She was recently diagnosed with (RMS) Rhabdomyosarcoma (Cancer) and faces a difficult road ahead of her and will need as much support as possible to fight for her and along side her.

Any donation would be greatly appreciated please share this as much as possible 🙏🏼❤️

[cltindia]

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[sarahdogoc80]

My Cancer Journey

Note: To protect myself and my family names will be changed. And I might leave some events vague because either I don't remember in full or for privacy reasons. TW : Cancer, Hospitals, parental abuse, suicidal thoughts, religious confusion.

When I was three I was diagnosed with rhabdomyosarcoma. This cancer is in the soft tissue of the foot and hands. It was in my left foot. When I was three I had tripped over a manga doodle. Due to the cancer making it to the bone it had started eating it causing it to be weaker thus easily broken. My mom had noticed the tumor and kept taking me to the doctors but they said it was normal swelling due to the broken bone. Around this time my parents were fighting. And my dad had kidnapped me to psychologically attack my mom. My dad would purposely drive into the driveway with the car door lock and laugh as me and my mom cried and tired to get to each other. The only reason my mom got me back was because my dad had missed an appointment my mom made months ago. That appointment would have told them I had cancer. But at the time they didn't know it was cancer but it was an important appointment my dad had technical kept me from. So my mom's parents managed to get a lawyer and get me back. When she got me back I had lice and a bad diaper rash.

When my mom found out I had cancer she was extremely vulnerable and my dad realized how bad he messed up so took advantage of my mom to drop the charges as he was looking at prison time. He pulled the I want to be with my daughter before she could die. So all he was charged with was parental interference.

He loved me so much that when they were told my parents they had to pay for the first round of chemo. My dad didn't want to pay for it and insed wanted to pay for my mom's fertility treatment. So he guilt tripped my grandma (she felt responsible for my cancer because I broke my ankle at her house. ). So my dad told her she had to pay for it and acted like he didn't have the money. So my grandma sold her car took up a second job and even begged her mother for money. To note my great grandma gladly gave my grandma the money as it was for my cancer treatment. My grandma just didn't want to ask he mother for money because she had to financially help my grandma though her whole terrible marriage. Because my grandpa was an ass at the time. But once my grandma got the money she was helping my mom clean my parents bed room and they found around 100,000 dollars in 2003 money, in shoe boxes. When my mom confronted my dad he said it was for my mom's fertility treatment because he needed a son. So because I was born with the wrong genitals my dad didn't care if I lived or died. And just used me as a pawn to hurt my mom.

My dad was hardly there my whole treatment. My mom said it's because he was always working which is true but he also just doesn't view me as valuable because in Mexican culture the boys are what matter. My dad later in my life said he wasn't going to waste his time on me because I was a girl and all I was going to be was someone else wife. My mom did get pregnant and she had my little brother. I wanted my brother. I even told the nurse who was doing the ultrasound I hope it's a boy because if it was a girl I'd throw her in the trash (I was three I didn't understand what I was saying... But I wonder why I had this opinion hmmm). Dispite dying of cancer I wanted to help my mom with my brother and we were inseparable.

During my chemo we found out I can't handle regular anesthesia. We found this out after the first time they put me under to I think either to do a biopsy or drill into my hips to make sure the cancer wasn't else were. While I'm a twilight state (my eyes were closed and I wasn't aware) I tried jumping out the car window on the highway as it started wearing off. My mom had to hold me down in the backseat because I kept insisting I had to jump out the window. This so a genetic disorder which mostly effects people with blue eyes. And while I had brown eyes my mom had blues eyes and also had this problem. An example is my mom while out for her hysterectomy she "woke up" during her surgery and said she had to pick me and my brother up from school. The doctor has to hold her down because she started getting violent. She wasn't aware of this and doesn't remember doing it. But we have this problem so when they had to put me out for surgery or just to get an MRI as I was very combative thought my whole chemo process. They had to use propofol (the stuff that killed Michel Jackson). And because this was 2003-2006 they had to have one the the nurses pump the breather by hand.

When my parents were discussing my treatment plan the children's hospital almost took my parents to court because they didn't want to do radiation treatment and just chemo. My parents said if they did radiation it would destroy my leg and foot and they'd have to amputate. Which was unacceptable to my dad. My parents wanted me to keep the foot and leg no matter what. As my dad didn't want a physical disabled kid. So they went with this very experimental treatment plan. Due to this being experimental my mom let them write about my case so long as they censor my name. So my treatment was used to help other kids.

Unfortunately in my teens I felt extremely guilty about this because I am in so much pain and the thought of this being inflicted on another kid hurt me. Infact I came face to face with this . Dispite my cancer being rare in 10th grade a girl in my school system was diagnosed with the same cancer and I had a mental breakdown. Because I met her (thought I didn't tell her I had the same cancer not that my research was going to be used to help her) but seeing her so hopefully and happy that she might survive. I just cried and cried because I didn't want this girl to be in as much pain as I was in. Especially because the opioid epidemic hit... So all I could get was lyrica and while it helped I was still in chronic pain. And the thought of her having to endure this just broke me. I started hating the whole medical system, resending I was considered a success case and that because I lived it was concerned a good treatment plan. I wrote several suicide notes outlining my pain and how the pain controlled and ruined my life. And I just wanted to kill myself because I thought if I did then they would have to consider it a failure and rethink how they treated it. I was in a dark place and I thought i would save this girl the pain if I just died. I never went thought with it though because my brother needed me and even though I was in an awful home life. I cared more about him then some girl I didn't know. I moved away from my home town so idk if she even survived but I hope she did and I hope they treated her better. And she is happy.

Back to 2003. I was very combative my whole chemo treatment causing me to have to be sedated or held down alot. While I didn't know the full scope of my ordeal I knew the chemo was killing me. And to watch my mother hold me down while injecting me with poison caused a lot of trauma. And because my parents hated therapy I never went after chemo even though the doctor said I should. But that also damaged my relationship with my mother because I knew the chemo was hurting me and to also see doctors doing this made me resent doctors my whole childhood. Thought because of this headstrong attitude I also told the hospital I didn't want a wig. My mom said I said quote "I don't care if I'm bald the other kids don't have to play me." Or something along those lines. Now I called a couple years ago so I don't remember which organization it was. But I very clearly remember a make a wish type organization coming to grand me a wish. My parents were excited because hey thought I was going to say Disneyland. But when I said I wanted to go to college to be a CSI agent or help murdered children they were pissed. After chemo when I wanted to go to Disneyland. My dad said I should have used my wish then if I wanted to go so badly. I would have wished for that if I really wanted to go. Supposably this organization has an education trust set up for me. But due to a flood my parents lost the paperwork, and no bank I call or make a wish type organization I call says they granted me a wish. So I don't know what happened to that.

Something I need to note is I was a child raised in a racist house. Yes dispite me being biracial both my parents were still racist towards each other races and others. So when a basketball star I think it was Lebron James but I could be wrong as I don't know Basketball stars. Came to the hospital to meet the children and their parents. My dad was a huge basketball fan. So when LeBron tried approaching me to give me a signed basketball I ran to my parents and refused to take it. My dad asked why I didn't want it(because he wanted the ball) I apparently told LeBron to his face I wasn't taking the ball from him because he was black. All the parents and nurses stared at my parents who left with me in "shame". When really it was because I did that out loud and embarrassed them and didn't just take the ball. Note: they didn't correct this racism at all. I had to correct myself and learn about other races when I got older. So I don't still hold any of these beliefs but I am being honest with how I was as a kid.

My parents did take one vacation on their own dime (I think) to Canada to go visit Hershey Park in the beginning of my treatment. But otherwise I was either at the hospital or home

My mom also started cheating on my dad at this time and bringing home her partner when he was at work. Looking back this really grosses me out. She just had my brother and I was dying yet she couldn't control herself for a couple years. And worse she bring them over to the house. I have no clue how she squeezed in cheating after having a baby with digestive issues and the other one is on chemo. But whatever.

My chemo is a blur and mostly just remember it as trama.

I guess a "funny" story is at the start of my chemo my grandpa noticed I wasn't eating and kept throwing up. So when he went to get my brother medication from a Native American friend of his (note: this friend was a Native American herbalist medicine doctor of some kind (sorry idk the correct term) in Arizona he gave my brother essentially probiotics (before they because main stream) to give him some gut bacteria my brother was missing. Honest to God they were going to cut my brother open to see what the problem was. And a week before the surgery my grandpa started giving my brother the powder and his stomach problems stopped.) Something else he got from this friend was a weed brownie. My grandpa was a hippie so he knew what weed was and knew what he was giving me. After I ate it my mom said I was eating like I hadn't in over a year, was laughing and spinning around. My mom asked what was up with me and my grandpa (her dad) laughed and said it was a weed brownie. Note my parents are both huge pot smokers infact my nickname is weed related. Lol. My mom was pissed because she was worried about it coming up in a blood test (the hospital never found out).

I also hate morphine. I still do. I would only take Tylenol at home for the pain. But at the hospital that was what they give me. This is were I learned to lie. Because I have a distinct memory of a nurse coming in to ask if I was in pain and that she'd make it stop. No one listened when I said as a kid I didn't like what they gave me for pain. So I started lying about not being in pain so they wouldn't give me morphine. No matter how much pain I was in I hid it so they wouldn't give me morphine. So that was a disaster. They started giving me I think liquid Percocet when I was in remission which I liked because it didn't make me feel like death and actually helped my pain.

Once they removed the tumor they tried giving me a walker and wanted me in physical therapy. Now I don't know if this was because the doctor weren't 100 sure about what they did to my foot and how it would affect me. Or the Physical therapist didn't get some notes. But they were trying to get me to do stuff I just physical couldn't do anymore or were extremely painful. So I started just sitting there and refusing to to anything because no one was listening and I wasn't going it be put though this. So I stopped going and taught myself to walk again my mom said. As for the walker they gave me I used it once then threw it behind our couch and never used it again.

Now I need to note I am an atheist (specifically part of the Satanic Temple) so I'm not trying to make this a religious thing but I'm telling you what I experienced. During my chemo another family member had his cancer come back. He was named Uncle N (not saying his real name). I became very close to him because we could understand each other. I remember we'd eat grape popsicles together. He was very old when I was born. He is like my great uncle. But the night I went into surgery he died. And even is believed to have died during my surgery. I was pronounced legally dead for 5 seconds during the surgery. I remember watching my own surgery. Then Uncle N came in. I was excited to see him. He told me it was his time to go and wanted to say goodbye. He told me to not give up. That it wasn't my time. And that everything would be okay. That he would watch over me. I was a little confused and sad and he told me he loved me and it was about time to wake up. I woke up with my family surrounding me smiling but I started crying saying uncle N died. They were all confused and said he was fine. My mom left her cell phone in the car and went to go get so I could call him and tell him they got the cancerous tumor out. When my mom came back she was crying and said uncle N was actually dead. My mom then asked how I knew. I said he visited me before I woke up. She wasn't really listening and everyone stepped out to cry. The nurses tried making me feel better all pitched in and brought me a fish cake later that day. Idk what I experienced. Idk if it was just the brain doing it's thing. But it felt real to me.

This is all I can write right now as I am crying. But if you have any questions feel free to ask. And I will definitely be going into detail about my life and how I was living in cancer's shadow. If you made it though thank you for listening.

[lushuponatime]

Crackle Bath Bomb from Lush

Today I am reviewing the recently released Crackle Bath Bomb from Lush’s 2024 World Bath Bomb Day collection.Out of the 29 bath bombs, Crackle is the only charity one. 100% of the sales price (minus government tax) will go to Dexter’s Arc, a children’s cancer charity funding non-animal testing research into Rhabdomyosarcoma. You can find out more about Dexter’s Arc (here).Just like me, Dexter…

[drpedi07]

Toronto Childhood Cancer Staging criteria for Rhabdomyosarcoma Calculator

Once the type of tumor has been identified, doctors need to assess, as accurately as possible, how much of it there is and where it has spread.

[thewrongjackpot]

Who needs to blog anymore when you have a therapist?

It’s been some time; more than just a hot minute. I had to look back and see how long it’s been. It’s been about nine or so months since talking about scans. I think from that appointment I was given a therapy contact and started up not too long afterwards. I feel that’s been bearing much of my emotional and mental weight lately. It seems pretty obvious that it’s something I should be doing, and here, I feel the need to justify going because of cancer trauma. Yet I, even without it, still probably end up going at some point. Cancer was just an extreme catalyst to get me to start. I can only use humor as a coping mechanism for so long. I was getting to a point where the dying jokes were becoming more frequent and getting old. It always makes me think of the scene from “Friends” where Phoebe is dating a therapist, and he asks Chandler something along the lines of “What happens when the jokes stop?”. 

Therapy has been good. I had learned about what secondary trauma is from my husband, and during much of the post-treatment times, I tried to stay conscious about what degree of information I divulged to certain people about how I’m doing. Because there are so many layers to all of this, and if they knew all the thoughts that cross my mind, all my anxieties, and just much of what I have to internalize, they’d surely be left with secondary trauma (assuming they actually cared). And I think the part that scares me is that dealing with the thoughts about “what if cancer ‘won’, and I died” are the easier ones. 

I talked to my therapist about how I’ll do certain things in “attention-seeking behavior” fashion like pull up my sleeves and causally put my Sally arm out into the world so that maybe it’ll act as heads up that something isn’t quite right with me. I think I’ve been using this platform as a way to indirectly, yet, directly tell people what’s going on in my head/what I’m dealing with. Like I’m not specifically telling someone this; someone chose to read it. Yet I’ll do things like post on my IG story that I dropped a new blog… so how indirect is it really? (I already know I’ll be guilty in the future …like how did you get here?) I think I use it as a way to absolve myself from some of the guilt of potentially traumatizing others by telling myself that they chose to read it; I’ve done my job and put out disclaimers. A part of it is in needing and wanting to be heard while at the same time not wanting to be a (direct) burden on someone else. 

I have this need to want to protect others from everything I’m going through, for example, my parents. I think it’d break their hearts to know all that I’m dealing with. Maybe I’m self-absorbed, but I feel that any caring and loving parent wouldn’t want to see their child handling everything I am or generally, someone dealing with very traumatic experiences. I can only imagine feeling fairly helpless. I’m not a parent (and who knows if I ever will or could be… and that’s a whole other set of onion layers), but I think that deduction isn’t far out-of-pocket. I’m very concerned with the toll my trauma could have on one of my loved ones (again, with the self-absorption). Thus, therapy is a safe space for me to just unload, unpack, and healthily work through much of what I hold back from others. 

Then there’s this weird atmosphere I create by internalizing much of it that it may give the impression that everything is fine. Then it feels odd if it’s not acknowledged, but I’m the one putting out this vibe that it doesn’t need to be talked about. Yet, I can sometimes feel forgotten if I’m not checked in on, but at the same time, I’m like, get off my back, I’m fine. It’s a weird space to be in.

I recently saw a TikTok…or a movie…? that talked about perception. How you’re the only you you’ll ever know, and that the only “true” you only exists in your head. Everyone else has their own version of you based on their perception of you. It’s been sitting with me lately. Thinking back to when I was going through treatment and people left and right were saying how strong I was or I’m a warrior for going through all of this. Not something I hear as often now as I’m done with treatment. Don’t get me wrong, I absolutely hate hearing it (pure cringe). However, the funniest aspect about it all, is that from my perspective, treatment, surgery, and all of that was the easiest part thus far. So much of that was dictated. I had all my appointments scheduled. We had a protocol for when certain things went wrong. I had doctors and medical staff essentially running the whole show. All I had to do was show up; driving my ass to appointments, as often as I could. Sitting in the hospital for a month or so at a time. I had no real choice outside of “let myself die”. I just had to show up; that’s it. I survived. I didn’t have to worry about anything else. My life was so regimented I didn’t have capacity to deal with or focus on anything other than showing up and sometimes rooting for my body to not kill me. I’m left with imposter syndrome from others thinking and saying I’m some strong person. 

And life moves on, treatment ends. I’m still around. There’s this err of “everything is generally okay now”, which depending on how you look at it, could be true. But all of this “after” has by far been the hardest part, again, from my perspective. Trying to reintegrate back into this unforgiving world with my new “normal”. Life keeps on going and stops for no one. There are days where it takes every ounce of me to just keep trying. Finding happiness in what pockets I can. Celebrating even the smallest wins. Rule 32: Enjoy the little things. Dying or having died is easy. It’s the living and finding reason to live that’s hard, even without the cancer sprinkles. I want to be hopeful and optimistic about this world and the rest of whatever life is gifted to me. There’s this persistent fight in my head against fully submitting to nihilism. I don’t want to be labeled (perceived) as that sad sap that gave up or let grief and anger be the drivers of my world. Being angry and/or sad at the universe changes nothing that’s already happened. It really just is what it is (sidenote: I legitimately want to get “It is what it is” tattooed somewhere eventually. I’ve lived by this long before cancer came along). 

ANYWAYS, as you can tell, I’m very much in my head. Just some later night rambles from your favorite failed X-Men. If you’ve got this far, do what you will with all this information.

[jcrmhscasereports]

Giant Cell Tumor of the Infrapatellar Fat Pad of the Knee: A Case Report by Ahmad Jiblawi in Journal of Clinical Case Reports Medical Images and Health Sciences 

ABSTRACT

Giant Cell Tumor is a rare benign soft tissue tumor occurring in two forms: localized and diffuse. The two subtypes differ in their location at presentation, shape, recurrence after treatment and prognosis. MRI is still essential in the diagnosis, however pathology remains the gold standard for the final diagnosis. In this article, we report a case of Giant Cell Tumor involving a very rare location with very few reports in the literature; the infrapatellar (Hoffa’s) fat pad of the knee. We discuss its keen clinical and radiological features. The tumor was managed with arthroscopic resection. Confirmation of the diagnosis was done by pathology. Our case is the first to be reported in Lebanon.

Keywords: GCT; Hoffa’s fat pad; STIR

INTRODUCTION

First described by Chassaignac in 1852, Giant Cell Tumor (GCT) is a benign soft tissue tumor [1]. It is a rare disease, associated with synovial inflammation due to hemosiderin deposition. GCT occurs in two forms: localized GCT and diffuse formerly known as pigmented villonodular synovitis. The former typically consists of small well circumscribed, nodule or pedunculated mass that might be intra- or extra-articular, most commonly (85%) in the small joints (ex: hands and feet) while the latter is typically intra-articular with an infiltrative growth pattern commonly occurring in large joints (ex: ankles and knees) [2–4]. Both share similar histologic features; however they have different biological behavior, treatment outcome and prognosis. Thus the importance of differentiating between the two entities [5,6].

MRI is considered essential for the diagnosis, staging, preoperative planning and clinical follow-up of GCT. The mass appears of iso/low signal intensity on T1 and T2 weighted images. In addition to joint effusion and synovial proliferation. Some “blooming” artifact of low signal might be noted on echo-gradient because of the magnetic susceptibility from hemosiderin deposition [1,2].

In this article, we report the first case in Lebanon (to our best knowledge) of a rare, localized Giant Cell Tumor originating in the infrapatellar (Hoffa’s) fat pad, emphasizing on its radiologic manifestation.

CASE REPORT

We report a case of a 35-year-old gentleman, previously healthy, complaining of a 4-month history of recurrent and painful left knee locking. The patient denies any trauma, any recent surgery, no accompanying systemic symptoms as of fever, rash, diffuse arthralgia, or myopathy. His presentation was mimicking that of a meniscal tear injury.

An MRI of the left knee was performed using 1.5 Tesla Philips Ingenia Unit, manufactured in the Netherlands. The following planes and sequences: A sagittal T1 weighted (T1W), proton density (PD) and STIR image, a coronal STIR and an axial STIR image (Figure 1 A-E). Result showed the presence of a soft tissue-like lesion arising directly anterior to the anterior cruciate ligament in between both femoral condyles estimated to be 3 cm in its transverse diameter, 2.7 cm in its antero-posterior diameter and 1.2 cm in its supero-inferior diameter. The lesion showed iso-intensity to the cartilage on T1W as well as on PD but showed an increase signal intensity on STIR weighted images. The lesion relaxes directly on the ACL posteriorly which is of adequate continuity and signal. Minimal associated excess of joint fluid filling the supra-patellar bursa. Both menisci, anterior cruciate ligament, posterior cruciate ligament and  medial and lateral collateral were normal. No capsule-meniscal separation is seen. The overall radiologic impression was for a Cyclops lesion or a soft tissue tumor such as Giant Cell Tumor.

The patient underwent an arthroscopic excision of the soft tissue tumor. Procedure went uneventful. The tissue was sent to pathology. Microscopic examination showed fragments of fibrous tissue involved by sheets of fibro-elastic to epithelioid cells with band nuclei and moderately abundant cytoplasm. They are intermixed with osteoclast-like giant cells and foamy histiocytes. There was no evidence of malignancy. Findings suggestive of Giant Cell Tumor of the Tendon Sheath. Unfortunately, the patient was lost to follow up, thus recurrence could not be reassessed.

Figure 1: AT1 weighted image, sagittal plane: showing a soft tissue-like lesion iso-intense to the cartilage measuring 2.7 cm in its antero-posterior diameter relaxing directly on the anterior cruciate ligament posteriorly which is of adequate continuity and signal B: Proton density weighted image, sagittal plane: showing a soft tissue-like lesion iso-intense to the cartilage measuring 2.7 cm in its antero-posterior diameter relaxing directly on the anterior cruciate ligament posteriorly which is of adequate continuity and signal.

C: Short T1-Inversion Recovery weighted image, sagittal plane: showing a hyperintense soft tissue-like lesion measuring 2.7 cm in its antero-posterior diameter. D: Short T1-Inversion Recovery weighted image, coronal plane: showing a hyperintense soft tissue-like lesion measuring 1.2 cm in its supero-inferior diameter. E: Short T1-Inversion Recovery weighted image, transverse plane: showing a hyperintense soft tissue-like lesion measuring 3 cm in its transverse plane.

DISCUSSION

Giant Cell Tumor is a rare benign soft tissue tumor arising from the synovial tissue of the joints, tendon sheath, mucosal bursas, and fibrous tissues adjacent to tendons. Multiple terms are found in the literature to describe this entity; pigmented nodular tenosynovitis, fibrous xanthoma of synovium, benign synovioma, xanthogranuloma and tenosynovial giant cell tumor [1]. Etiology and histiogenesis of which is not completely understood, but many risk factors were mentioned in the literature such as trauma, infection, vascular abnormalities, lipid metabolism disorders, osteoclastic proliferation, and immune system disorders. It can present in two forms: localized and diffuse [3,7]. Localized GCT presents mainly in small joints (85 % observed in fingers while 12% is observed in large joints, GCT in the knee is rare) [4], either intra-articular or extra-articular. Diffuse form occurs mainly in the extra-articular space [8]. However, extra synovial soft tissue forms of localized GCT are very rare and mainly concern the knee joint. Around 50% of patients with a localized GCT arising primarily within the infrapatellar fat pad have a history of trauma but the exact etiology is still unknown [9]. The onset age of localized GCT is older than that of the diffuse type (i.e. localized type usually occurs above 40 years of age)[10]. When affected, patient presents clinically with mechanical derangements, progressively worsening over time. Meniscal symptoms and locking are often present within the knee joint. The main symptoms are swelling (86%), pain (82%), stiffness (73%), limited range of motion (64%) and joint instability (64%) [7,10].

MRI is an effective and highly sensitive diagnostic tool; however pathology is still the gold standard of final diagnosis. On T1 and T2 weighted images, dense collagen and hemosiderin presents with homogenous low or intermediate signal. The most typical feature of a localized GCT is a well circumscribed, nodular mass with low signal intensity on T1, T2 and proton weighted images and high signal intensity on STIR images [4,6,9,10]. Microscopically, GCT is characterized by multinucleated giant cell, lipid-laden macrophages, hemosiderin deposition and fibroblast proliferation [5].

Various pathological conditions should be considered in the differential diagnosis, for example: Synovial Chondromatosis, Cyclops lesion, Rhabdomyosarcoma, Fibroma of tendon sheath, Synovial Sarcoma, Amyloid Arthropathy, Haemophilic Arthropathy, Lipoma Arborescens and Rheumatoid Arthritis [6,9].

The ability to differentiate between the diffuse and localized forms of GCT is paramount to give patients a realistic outlook on future prognosis, chance of recurrence and optimal treatment course [5]. Several treatment options are present: surgery, radiotherapy, pharmacology or a combined solution of the listed methods. Important to note, local recurrence after treatment was reported in 18-46% of cases. However, this might be linked to incomplete resection of satellite nodules in the area of initial change. Other risk factors for recurrence are the location of the disease (more common in the knee), history of previous surgeries and positive surgical margins.

CONCLUSION

To the best of our knowledge, our case is the first to be reported in Lebanon. It is very rare to have a localized GCT in the extra-synovial infrapatellar (Hoffa’s) fat pad of the knee. The rarity of the presented case suggests that GCT should be considered in the differential diagnosis of a painful knee locking in a young patient. Accurate diagnosis will lead to successful treatment associated with low recurrence rate resulting in a better patient outcome.

Conflict of Interest:

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article

For more information: https://jmedcasereportsimages.org/about-us/

For more submission : https://jmedcasereportsimages.org/

[chetanagblog]

Rhabdomyosarcoma Market size was valued at US$ 1.66 Bn. in 2022 and the total revenue is expected to grow at a CAGR of 3.7% through 2023 to 2029, reaching nearly US$ 2.15 Bn.

[mindblowingscience]

Scientists have successfully induced rhabdomyosarcoma cells to transform into normal, healthy muscle cells. It's a breakthrough that could see the development of new therapies for the cruel disease, and it could lead to similar breakthroughs for other types of human cancers. "The cells literally turn into muscle," says molecular biologist Christopher Vakoc of Cold Spring Harbor Laboratory. "The tumor loses all cancer attributes. They're switching from a cell that just wants to make more of itself to cells devoted to contraction. Because all its energy and resources are now devoted to contraction, it can't go back to this multiplying state." Cancer isn't a monolithic thing. It arises when cells from different parts of the body mutate. Rhabdomyosarcoma is a type of cancer that's most often seen in children and adolescents. It usually starts in the skeletal muscle when cells therein mutate and start multiplying and taking over the body.

Continue Reading

[sideshow-tornado]

Gonna bullet point this and pin, since my original post was getting a little too long.

My 16 year old niece Ava was diagnosed with Rhabdomyosarcoma, a type of soft tissu cancer, just over a month ago; after a previous misdiagnosis of Bell’s Palsy when a growing mass was discovered behind her left eye and cheek.

They caught it early but it’s also aggressive, and she has a genetic mutation that makes this particular type of cancer more aggressive.

She is receiving weekly chemotherapy treatments, but has had some setbacks including being hospitalized with a fever; and during a surgery to preserve one of her ovaries her bowel was nicked and had to be repaired.

The doctor’s are giving her a 50% chance of survival, as per Ava’s request, we have asked for honest and unfiltered information. She is not doing so well, already lost so much weight and hair, not eating much. But getting a lot of support and treatment, and encouragement, but it is a grim present.

Ava’s mother and ex-stepfather have had a contentious divorce over the last two years, including an ongoing custody battle with Ava’s younger sister. And Ava’s adopted older sister died of a rare brain tumor just over a year ago.

She’s had a rough go of it during her short life. I’ve done my best to be positive and loving influence. Ava is strong, has always been as feisty as she is sweet. She wants to live.

Any donation would be greatly appreciated please feel free to share the link. Thank you.

[allienoelle93]

At this time, Lorelai needs round the clock care. Any way you could help would be amazing. Please donate, like and or reblog.

[cltindia]

Alcohol Rehabilitation Centre in Mumbai – Rehabs India

If you or a loved one is seeking help for alcohol addiction, Rehabs India offers access to the best alcohol rehabilitation centres in Mumbai. Our partner facilities provide comprehensive treatment programs, expert medical care, and a supportive environment to help individuals on their path to recovery.

[terry-on]

Asking for help

My 15 year old daughter was recently diagnosed with a very rare ovarian cancer called Sertoli Leydig with Rhabdomyosarcoma. It has spread to her stomach and she has an extensive chemotherapy schedule. Paid vacation days are almost out and Family Medical Leave is unpaid. I am humbly asking for any help you can give to me and my family Please share even if you can’t donate. Thank You 🙏❤️‍🩹

[drpedi07]

Toronto Childhood Cancer Staging criteria for Non-rhabdomyosarcoma soft tissue sarcoma Calculator

Non-rhabdomyosarcoma soft tissue sarcomas (NRSTS) arise in the soft tissues of the body and account for less than 5 percent of all pediatric cancers.