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#quality of male sperm
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Understanding and Managing Male Infertility: A Comprehensive Guide
Male infertility is a deeply personal and often overlooked issue that affects millions of men worldwide. It’s not just a medical condition; it’s a subject tied closely to identity, emotional well-being, and relationships. With approximately 15% of couples globally struggling with infertility, male factors account for nearly half of these cases. This expanded guide delves into the intricacies of…
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reyuk123 · 1 year
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Maximise Healthy Sperm with Effective Supplements
Discover the power of effective supplements to enhance and maximise healthy sperm with Kindly Health's premium range of natural and scientifically-backed products. Our supplements are specially formulated to support male reproductive health, improve sperm quality, and promote overall fertility.
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nocturni3 · 1 year
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Miguel O’Hara x male reader: Daddy appreciation
Top reader
(TW: incorrect Spanish I’m not a Spanish speaker sorry, praise kink, IVF reference, infertility issues, depression, infertility treatment, IVF struggles, fatherhood, anal sex, handjob, body worship, doggy style, becoming parents, celebrating, slight daddy kink, slight public teasing, slight car sex, edging, stomach bulge, breeding kink, submissive headspace)
Months passed since the two lovers became engaged and things couldn’t be better for them both. It was as though things were beginning to look up for both Miguel and M/n as they moved outside the city; away from the loud noises, most of the crime, the stresses of Miguel being spiderman.
After Tyler Stone vanished after his failed attempt at getting his CEO position back from Miguel, Alchemax was slowly turning into a big corporation that began to take the city's poor and lower classes protests seriously. A corporation that both M/n and Miguel could be proud to work for.
With the help of Miguel’s mother as his secretary much to both men’s surprise she was good at both being a threatening force and yet a silvered tongued negotiator. What’s more M/n’s department got more funding to extend a larger hand in downtown clinics and ERs providing them with the newest and safest tech during surgeries, and treating illnesses and diseases that had been neglected by Tyler Stone.
It allowed M/n to move all his major work as head of the medical engineering department to their home; it felt unreal as though this shouldn’t have been possible for Miguel to live happily in a loving relationship with a house, and a ring on both fingers. Spiderman was needed less and less as most of the villains that littered the city were falling back into the shadows with Alchemaxs change of CEO, the change needed for a better future for everyone.
Looking around his new and much larger office that Miguel shared with M/n; he sighs, taking off his tinted glasses as he shuts the hologram screen off; after signing off another approval for the start of a more powerful environmental power grid to be placed downtown. To help clean the pollution and gasses that permeated the air quality.
Rubbing his sore eyes Miguel sighed as he leaned back in his chair, allowing himself to breathe in the smell of M/n cooking them both an early lunch before their doctor appointment. An appointment they both were excited but scared to go too. After all it would be their 5th appointment of seeing if Miguel’s constant supplements had helped any with his sperm count; one of many side effects of his DNA being spliced with a spider. An effect he hated, despised so much that Miguel was losing hope with each failed test, with each failed attempt at fertilizing the donor's eggs; eggs that were running low with each failed appointment.
Miguel had his fair share of breakdowns as this was their best chance to have a kid, as M/n was deemed infertile the second round of IVF. A fact that had broken the two men; a hard fact that had all the pressure placed on Miguel which M/n tried his best to help Miguel through, but there was only so much his love and support to ease the pain and hole forming in Miguel’s chest each time they got the news of yet another failure.
Even with technically advancing the way it has been compared to the early versions of IVF in the early and mid 2000’s to now with the child being grown in a womb like environment eliminating the risk of miscarriage by a large margin.
There was only so much technology can fix when it came to a genetic code being altered in the way Miguel’s has. Only so much injections of enhanced vitamins could do for a body that was genetically modified, only so much it could fix an already broken-
“Miguel hun, lunch is ready! And your medicine too love
Miguel groaned, rubbing his face even more as the knot in his stomachs made it harder for him to want to eat anything. Made the decision to just ignore this one appointment to just wallow in his own self pity; maybe then Miguel wouldn’t need to take anymore injections. Resting his arms on the glass surface of his office table Miguel felt the tired, mental exhausted tears start to purs into his eyes as he tried his best to control the painful knot in his chest at the thought of this appointment being another nail in his self worth.
M/n looked at the still closed door of Miguel’s and his office. Seeing no sign of Miguel coming out M/n whipped his flour covered hands looking at the plate of hot steaming beef and veggie empanadas he had just finished cooking .
A recipe Conchata had given him after the two revealed their engagement to Miguel’s family; who all accepted the fact it was either accept the two for their love of the other or they’d lose Miguel for good.
M/n remembered holding Miguel’s hand throughout the entire exchange. He still held his finances hand through this difficult time in their lives; wanting to have a child to call their own. M/n despised not being about to take all the weight off of Miguel; he wished he could be the one going through the bull of the stress and pressure of these appointments.
But he wasn’t…he was completely infertile; the Lilly hood of him having a kid even with IVF was zero. The least he could do for Miguel was make him as comfortable as he could for as long as the both of them wanted to keep trying.
After all it was ‘through sickness or health, til death’; the ring on his finger made it all a reality. They were starting the next chapter of their lives together. The wedding was all set up, the venue paid for, their suits tailored and ready. They bought a house! But even that wasn’t enough for what their hearts truly craved for a child; a kid they could both raise and watch grow up with two loving parents; far from the toxic lives the both of them had to endure.
They just had to wait and hope that this appointment was anything but good news for them. Placing the dirty kitchen towel on the counter M/n dusted what was left of flours and spices on his shirt. Before making his way to the closed black door of their modern homes office.
A light knock echoed throughout the house as m/n waited with baited breath for Miguel to answer him. Give him time to regain his composure before m/n enters.
Lyla looked over to Miguel who quickly wiped away the stray tears that escaped his normally composed face. She saw how much the two wanted a kid, even going as far as to pick out names ahead of time while planning their wedding. Even though she was sentient now she was still very limited on what she could do to help.
“Miguel”
“Hm”
Lyla forced a smile as she appeared next to Miguel’s shoulder, leaning over to look into his eyes getting his attention.
“M/n made your favorite!”
Lyla smile widen seeing Miguel’s frown turn into a small smile, as he scoffs his face turning a shade of red as he once again mumbled,
“Shock, ¿qué hice para merecer a alguien como él?”
Lyla disappeared and reappeared, informing Miguel, smiling as she pulled at a holo pad tilting her glasses down on her nose as she spoke in a joking assertive voice.
“Ah well let’s see, you and hot stuff over there met, we’re friends for four years and in that same year became boyfriends, then from then on you two dated, kissed, kissed, oh wow looky! Nope, more kissing, proposal and now you two are trying for a kid!”
Lyla froze her small bit hitting a sore subject as she tossed the holo pad over her shoulder listening to it canish in pixels as she turned to see Miguel’s face turn hopeless once more.
“Trying and failing-“
Lyla quickly appeared in front of Miguel shushing him.
“Listen here! And listen closely Miguel, you're not failing! You and M/n aren’t failing at anything, you’ll see Miguel things will start looking up for the both of you-“
A soft knock at the door was heard as M/n’s voice spoke up. His voice was soft, calming, warm as he spoke to Miguel.
“Hun are you okay? Is it okay if I come in?”
Clearing his throat Miguel waved Lyla away who huffed as she disappeared to another part of the house, continuing her installment of security measures.
“You don’t have to ask, this is your office too”
The door Jared opens revealing m/n whose clothes even after his attempt at dusting them off still had flour sticking to his shirt. Miguel smiled at M/n who made his way into their shared office, his eyes falling on the old day of the dead costume now turned spiderman suit that now mostly stayed locked for the time being behind a glass case.
The memories of Miguel saving him from a hostage and mugging, the moments the both of them spent in the other's arms comforting the other. loving each other with all their heart; Looking over to Miguel who began to fidget slightly as he started getting up only for M/n to make his way over to the stressed out man in front of him, placing his hands to Miguel’s tensed shoulders gently pushing him back into the comfortable office chair. Before leaning over the man who's had too much stress placed on his shoulders.
Leaning down M/n smiled his lips grazing Miguel’s, as he spoke his own hands running down Miguel’s muscular shoulders to his thighs massaging the even more tensed muscles. His hot breath landed against Miguel’s now parted lips as his focus turned from the stresses of their appointment to a need for a taste of M/n.
Miguel took in his fiancés appearance, his s/c skin that always seemed to glow anytime Miguel layed eyes on him, his H/l H/c hair that always managed to fall in the right places to frame his handsome features just right; enough to take Miguel’s breath away even after all these years Miguel would somehow still be flustered by the man in front of him.
“I know, but I figured you needed some time to yourself, didn’t want to interrupt your work mr. Sexy CEO”
M/n purred, closing the distance between their lips. Miguel sighed, feeling his entire body feel lighter as his hands reached up to take hold of M/n’s jaw gently rubbing it as they kissed.
The rhythm they kissed, the soft yet yearning for the others lips even after they had pulled away left the two nearly breathless as they stared at the other.
M/n smiled, leaning his face into Miguel’s hand, his own reaching for Miguel’s as they simply took in the atmosphere of this moment. The smell of food filling the air reminded the two of the meal waiting for them. Miguel sighed his face that had once been soft and relaxed after so long of stress now tensed at the approaching appointment. Another disappointment-
M/n kissed Miguel’s temple, feeling the pulse of the stressed out man in front of him who’s heart was beating rapidly.
“I know that face hun; this appointment has to be good news-“
“And what if it isn’t!”
Miguel shut his mouth at his outburst, his eyes burning once more that the thought of their doctors telling the couple more bad news or worse she’d tell them Miguel's sperm fertility was just not improving…that.
“Hun, it’s not hopeless, shock don’t say that anything but that, please.”
M/n’s voice creaked, he shook his head shoving his own feelings down, focusing on what he should say to Miguel who was losing hope.
“What else should I say, Cada visita es solo una pérdida de tiempo. I want to raise a kid with you so badly; I want to have a normal family with no strings attached…but every time we try Esta maldita genética mutante todavía lo arruina todo!”
M/n wiped away Miguel’s tears, ignoring his own that streamed down his face. They wanted to complete their family so badly, to raise their own family, to live a normal calm life. Seeing the man in front of him break down, his heart wide open and exposed, raw with grief and self hatred. He hated seeing Miguel so broken; going from a confident, strong headed, sarcastic hot shot to a broken mess in his arms M/n wanted to just take all the pain away.
“Miguel don’t say that”
“But it’s true, if I never tried to cure myself, never got my genetic code rewritten with a spider we wouldn’t-“
“I wouldn’t be alive”
“Huh-“
“Miguel, if none of this happened to you, if you never became spiderman…I would’ve died that night. Spiderman wouldn’t have saved so many lives, and even if you weren’t spiderman we both know you wouldn’t have just sat by and watched Alchemax keep hurting people. Things happen in ways that force us all to adapt, evolve in ways that shock even ourselves, be it in a positive or negative light. But don’t ever hate yourself ever, no matter what happens now to the future miguel I’m just happy to have you in my life, to have a kid with you and we will Miggy we just have to be patient a little bit longer”
Miguel leaned his head into the crook of m/n’s neck as he let out a shaky breath, wrapping his arms around m/n waist and back breathing in his scent. Mixed with expensive cologne and food had Miguel’s heart lighten; feeling truly at home in m/n’s arms, holding his soon to be husband.
“Estoy tan cansado de esperar”
“Oh hun I know, I know but we have to try and stay positive the best we can…which food can help com one handsome let’s eat and get you your injection before the doctor tears our heads off”
“Ugh, shock not another shot”
M/n stood up taking Miguel’s hand pulling him up from his chair pulling the muscular taller man against his own chest. The sounds of birds outside singing with the distant sounds of yard drones cutting the neighbors yards. It felt truly like home, staring down at M/n who caressed Miguel’s jaw luring him down for a peak.
“It’s just a small prick, besides hun I made your favorite food; managed to get your mom’s recipe”
Miguel peaked those intoxicating lips once more, his arms wrapping behind his lover's head. Untaloned Mighuel ran his fingers through the soft hair; gently tugging out knots as he gazed into the E/c eyes that stared back at him with such love it only luring him in even more; a siren song with no dangers.
“And how did you manage to do that? That woman keeps her recipes closer to her heart then that hun of hers”
Smirked, M/n flipped his head to the side, side eyeing Miguel.
“I have my ways, she’s not so secretive if you hang her dirty laundry out in front of her. Besides, it’s the least she could do after dragging our love through the mud. Now stop deflecting, let's eat before we go okay. And Miguel I love you just remember that no matter what I love you”
Leaning down Miguel pressed the twos for heads together, smiling allowing his teeth to show. His old confidence came back in full; feel much better than before.
~~~~~~
At that moment he was, but now that the couple sat in their room waiting for their reproductive endocrinologist Miguel became an anxiety riddled mess as he sat on top of the examination table trying to at the very least keep his talons in check as to not hurt the hand that was intertwined with his.
“Shh babe, just remember to breathe okay.”
Miguel tried to follow m/ns advice but even that wasn’t helping as Miguel squeezed his hand slightly as he kept his eyes moving around the room, reading the small posters featuring information on IVF and it’s almost beaconful message of;
‘We make families whole!’
Scoffing Miguel looked over to M/n who had his full attention on rubbing Miguel’s clenched hand, trying to sooth Miguel’s anxiety. Realizing he was hurting him Miguel eased his grip on his reassuring fiancé who leaned over in his chair placing a tame kiss upon Miguel’s quivering one.
His voice was like satin, soft and calming as he spoke with such confidence Miguel yearned to have such hope like M/n had.
“She’ll be here real soon hun, they are very busy today”
“I know but we’ve been waiting for an hour! Can they get this over with-“
“Hey now what did we talk about in the taxi hun?”
Miguel wanted to cop attitude but seeing the look M/n gave him Miguel sighed, taking a deep breath calming his already breaking heart at the news he knew they’d get once again. Breathing out Miguel pressed his head against M/n’s staring at their interwoven hands staring at the red diamond that sat set into the tungsten carbide band engraved with the couples most charashed phrase,
‘Mi única luz en la vida’
Words Miguel knew were far more truer now than ever before. His gaze soon fell to staring at m/n who smiled softly, even though he looked hopeful Miguel sensed he was just as much of a nervous wreck as he was.
“Try and stay hopeful-“
A small knock interrupted the couples thoughts as their doctor walked in, her holo pad along with her AI who processed the data came walking in. She was anything but a straight to the point, take not shot doctor. As she looked up her glasses caught the bright lights that had Miguel wearing his tinted sunglasses.
“Mr.O’Hara and Mr.L/N; I know you both what nothing more then to know the news-“
M/n smiled his voice loud and excited as he gave Miguel’s hand a slight squeeze as he spoke.
“Do we ever, it’s good news right doc?”
Miguel felt his fiancés hands shaking as they clasped over Miguel’s. Who now comforted M/n as his voice cracked some. Miguel clenched his teeth as tears began to gather.
“You both have been going through the highest levels of IVF, the most expensive treatments for infertility in men your age group and on top of that 5 separate appoints with no promising outcomes-“
‘Here it comes-‘
“Which is why I’m pleased to tell you both good news!”
Tears fell from Miguel’s eyes as he looked at the doctor, his and M/n’s hands gripping earthers tightly as the news left the doctors lips, her smile widening as she call for her AI to pull up the photos of a artificial womb with a small fetus floating within a time counting down twirls the date their child would be ‘born’.
“You both will be proud dads of a healthy baby girl! Congratulations!”
M/n yelled out pulling Miguel into a tight embrace, tears streaming down both soon to dads faces. Miguel began crying as well as he gripped the back of M/n’s shirt as he sobbed in pure relief of happiness. Almost disbelief as they stared at the photo given to the two of the child’s ‘ultrasound’. Standing up M/n wrapped his arm around Miguel’s waist as he asked the doctor questions Miguel didn’t bother to pay attention to as he held the photo in his hands, seeing their baby, their own daughter! Alive and healthy, a clear bill of health.
“When will she be fully developed I know this kind of new technology is recently upgraded and such with nutrition and growth potential en-“
“She’ll be born and ready for the both of you to take her home in around 3 months as long as she stays on the growth patterns she’s been showcasing. Rest assured mr.m/l, ohara we’re ensuring this little princess will be well taking cared of and safe”
Both parents sighed at the news, Miguel looked over to M/n who looked about ready to start crying himself at the news. The news they’ve been waiting for so long; was coming true, they’ll be parents with a baby girl running around. A strong, healthy baby girl.
“Now then I’ll just be right outside filling out your paperwork make sure to talk to the front office for your own paperwork to fill out, her name, legal parents that sort of thing, nothing to serious”
Miguel still could barely believe it even as he looked back down at the ultrasound seeing the small fetus that would soon grow into a baby; Their baby, migue leaned his body weight against M/n who smiled tears filling his own eyes as he held his fiancé.
“Thank you Dr.Lee, I-I don’t know how to even word just how much this means to us.”
Dr.lee smiled, placing a hand upon the couple's still interwoven hand.
“No need to thank me for doing my job, and once again congratulations Mr.l/n, Mr. ohara”
The door closed behind the doctor giving the new parents time to process the news of their daughter. M/n squeezed Miguel’s body closer to his as the two stood looking at the small ultrasound of their daughter. M/n smiled as Miguel's lips crashed against his own in a raw emotional moment of tears of both fathers, as overjoyed tears streamed down their faces: as all the stress and heartache finally vanished after months of wanting and waiting for this same news.
“W-we’re having a baby”
M/n smiled down at Miguel pulling his body flushed against his chest his hands gripping him by his waist his fingers soon running up Miguel’s white long sleeve shirt messaging the tension in his back out. Littering Miguel’s tear stain face with peaks with sweet nothings.
“ we’re having a little Gabriella, you did it hun; shock im so happy right now!”
Miguel’s eyes brightened kissing M/n back with a new found exuberance at the realization of this being real. That this was happening, that they were starting a family together. With a daughter they both always wanted Miguel’s hands wrapped around m/n’s neck basking in the joy the two felt,
“I guess this is the part I admit you were right?”
Laughing m/n held Miguel’s face in his hands leaning close enough for their noses to touch.
“Nah, I mean sure it’s nice to be proven right but now all I care about is that our daughter is safe and healthy and taking you out to celebrate…maybe invite the family?”
Miguel laughed, nudging his nose against m/ns shaking his head.
“You just wanna show off Gabriella don’t you”
“And why shouldn’t I? After all she’s our daughter, our strong, healthy, beautiful baby”
~~~~~
M/n couldn’t keep his hands to himself during dinner; and how could he? With Miguel sitting beside him as he spoke to Gabriel who seemed more distant and out of it, Miguel tried not to get sidetracked with the hand that slowly moved its way farther up his thigh. But the more he tried to ignore the hand that rubbed up and down his thigh getting closer to his slowly stirring cock. Trying to calm his body’s reaction Miguel tried asking Gabriel how his own fiancé was doing with her pregnancy.
“Oh she’s fine…when she’s not obsessing over spiderman. After all he’s the protector of the people right?-aye mamá! ¿Para qué era eso!”
Gabriel winced as Conchata hit the back of his head with his palm as she finished drinking her drink. Setting the drink down she turned to Gabe who seemed to know he messed up poorly as she began talking in her authoritative voice that made even Miguel tense up as. M/n tore his eyes away from the uncomfortable situation of watching an adult being ridiculed by his own mother.
“that was for disrespecting the man who managed to keep downtown safe while your stupid fiance and her useless rebel group got in spider man's way most of the time!El hecho de que esa rata sin hogar te haya abierto las piernas no significa que empieces a faltarle el respeto al hombre que está ayudando a tu hermano a sacar el crimen de las calles.”
Miguel had to force his face to stay as blank as he could as he took a bite from his meal, staring at the two members of his family arguing. While trying his best to not buckle against M/n's hand that now cupped his covered cock in his hand.
Messaging the area with a straight face side eyeing Miguel with a look that had Miguel’s stomachs knot up with lust; his cock throbbed against M/n’s hand earning Miguel a smile from M/n as his attention turn back to his mother and brother who were in an argument that was gaining some attention from the other people eating; clearing his throat M/n smiled at the two as he spoke a lovable tone calmed the two in laws down as he spoke.
“What we wanted to tell you both is that well…Miguel did we grab the photos?”
Miguel took a sip of his drink, nodding clearing his throat as he reached into his pocket grabbing the two ultrasound of the IVF womb with their soon to be daughter inside looking in her seventh month. Miguel’s hands shook not from nervousness even though he knew his mother and brother would take it as such but that was far from the reason he was quivering as the hand messaging his slowly hardening cock rubbed and cupped around him firmer.
“Mamá, Gabriel y M/N y yo estamos teniendo un bebé.”
Miguel’s smile widened, handing his mom and baby brother their own ultrasound pictures of his and M/ns baby girl.Gabriel practically yanked the ultrasound out of Miguel’s hand only for his scowl to turn into a look of pure adoring as he looked at his niece, his face beaming at the small image.
Conchata grabbed a hold of the small photo looking at the ultrasound . The stoic scowl that seemed to always be stuck on her face vanished as she looked down at the photo running his hand over the polished image of the baby curled up covering its face.
“Do you know the gender yet?”
Her voice softened as she stared over at the couple who looked at one another for permission. Miguel smiled at his mom,
“She’s a girl, a strong, healthy girl”
“What are you naming her! Did you come up with names yet?”
Gabe shouted as he leaned over the table at the couple.
“Yeah we settled on Gabriella for her. It just fits her don’t you think”
M/n's hand lightened its messaging of Miguel’s covered cock, Miguel’s one hand gripping the hand in place wanting it to stay, to keep its teasing as it stroked the straining fabric against his now hardened cock.
“Sure does! Now I know how to embarrass her haha Gabriel and Gabriella! Genius M/n!”
“Actually man it was Miguel who chose the name. He seemed dead set on the name and who am I to tell him no”
M/n smirked, kissing Miguel on his cheek; Gabriel’s chest clenched seeing the happy couple. Seeing his older brother aka spiderman in a loving relationship while his own as being torn apart because of Spiderman!
Looking away Gabriel grabbed his drink, chugging the rest of the alcohol, getting an elbow in his ribs by his mom who corrected his manners.
“Don’t drink like that”
Resisting the urge to yell at his mom who now favored his more successful CEO brother. Instead Gabe apologizes for his hasty celebration. Congratulating the couple before standing up excusing himself for leaving early.
“Do you want us to pay for a taxi for you Gabe!-“
“No, I'm good! Congrats again miggy!”
Miguel sighed, placing his head into his hands rubbing his temple looking towards his mom, who was now standing up grabbing her jacket, rolling her eyes at Gabriel’s ‘childish behavior’ stating she had to get going. Saying she had an appointment with a friend.
As both of the couple watched as the two rushed out leaving M/n and Miguel alone at the table. M/n’s other hand guiding Miguel’s hurt expression to face him kissing his fiancé who’s family rushed out as fast as they came. M/n knew the family had a toxic streak but to just ditch a celebration of a new member of the family coming soon…m/n knew it cut Migue deep.
Leaning forward M/n pressed his lips against Miguel’s, being glad the couple chose a booth seat as not many people bothered to look at the couple.
The hand that messaged Miguel’s cock gripped his balls harder, fondling them the best they could with; making Miguel pant, trying to keep his face and noises down as they were still in a public space surrounded by intel’s other people.
“We’ll celebrate in our own way after all You're getting pretty horny now aren’t you hot stuff?”
Miguel’s other hand gripped around M/n's wrist for support as his hand began palming his cocks head through his jeans. It took all his will power to not throw his head back from the pleasure and teasing he never knew he missed getting from his other half; who’s lips brushed against the shell of his ear, his hot breath brushing against Miguel’s skin had his skin shiver with goosebumps all in anticipation…hinging on every word the man in front of him whispered.
“Wanna treat my baby’s daddy just right, gotta make him feel real appreciated”
Miguel let out a soft gasp moan as lips trailed down his jaw to his neck. Miguel couldn’t take much more, his cocks throbbing became painful, his legs were turning into jelly at the images runny through his dirty, horny mind.
Would his throat be fucked raw? On his back taking his lover's cock? Would he fuck him like an animal in heat, pull his hair, mark him. Miguel’s grip tightened around M/n's wrist while his free hands talons tore through the leather of the booths seats.
Feeling M/n smirk against his neck Miguel sighed leaning his head against m/n chest; embarrassed wasn’t the word he’d describe himself, there was nothing to be ashamed of when it came down to their lust for each other, PDA a sign for either of them to get home fast or there was no stopping them from indulging in their carnal desires for pleasure.
For many men Miguel’s size being the ‘bottom’ was embarrassing, to look too weak so fragile for any amount of touch to satisfy their needs. To Miguel it was pure bliss to let the walls down to let someone else take control to be in charge of his own pleasure. Someone like M/n who knew Miguel’s body inside and out, knew ways to make Miguel go limp at the near thought of getting fucked raw with carnal, primal lust and desire.
Feeling m/ns lips leave his neck Miguel clung to him jerking his hips slightly against the hot palm rubbing him through his pants. His focus was beginning to slip with each thrust of m/ns palm against the head of the aching cock. So much heat burning in his stomachs Miguel felt his control slipping even more as his fangs ached leaking bits of his own venom into his mouth mixing with his drool in ways that had his tongue buzzing with the bitter sweet taste.
“Por favor, te necesito tanto que duele el amor”
M/n's hand palming softened its unbearable teasing as he pulled Miguel’s head into his neck area as his voice shouted out to their waitress. Miguel’s large muscular body tenses at slight fear of being caught in the act had Miguel regain some sense through the cloud of heated lust.
“Excuse me, could you call up an auto taxi please? We both must have drank more than we thought.”
Miguel let out a strained moan at the sudden strong rubbing that started once more. His mind rendered into a fog of pleasure struggling to keep itself focused on the act of staying aware of the situation they were in. He could hardly even focus on what their waitress was saying.
“Oh of course sir I’ll go do that right away, was your automatic payment set up for when you leave?”
“Oh yeah it’s all set up, tell the cooks good job on the food yeah and here's a tip for the trouble.”
“Oh there’s no need but thank you so much sir, the taxi will be here soon!”
Miguel let out a groan of relief with the deparcher of the young waitress. Trying his best to play it off as him being ‘drunk’ that didn’t stop M/n from kissing down his jaw to his neck, nipping at the sensitive skin near Miguel’s ear; sucking the skin leaving hickeys from his jaw down his neck. The grip Miguel’s talons had on the leather seat tightened even farther, tearing more of it in their wake of pleasure.
“joder a la mierda por favor necesito sentir tus manos a mi alrededor, I can’t take it anymore-“
“Mr.l/n your taxi is here!”
Miguel’s face tensed his eyes clenched shut, his lips swollen from his teeth biting down to keep the moans from pouring from them. But m/ns hand didn’t light up even as his sweetened voice. But Miguel knew the slight straining behind it as M/n's hand tugged Miguel’s shirt from his pants helping Miguel hide his rage ig boner as the two stood up.
M/n gathered most of their stuff, wrapping his hand around Miguel’s waist as he ‘helped’ Miguel walk outside to their taxi that waited for them, it became harder to walk from the anticipation of whatever was in store for him once they both got into the hover car.
Tossing their coats into the hover car M/n held the door open for miguel who only had one foot into the car before hands rubbing up his covered spine before lips kissed behind his ear, Miguel groaned when a hand gripped his straining cock firmly before letting Miguel go to get into the taxi.
The autopilot chimed on,
-“Please enter in destination requirements”-
M/n closed the doors hatch, without hesitation M/n swung his leg over Miguel’s legs straddling, his knees m/n’s face blocking much of Miguel’s view as he racked his hands all over Miguel’s muscular body.
Both adults eyes filled with lust for the other, Miguel’s body could help but shake as hands that weren’t his own started running up his thighs landing just shy of the raging cock that throbbed underneath the slowly staining fabric. Miguel barely had time to hit enter on the holo pad before the hands unbuttoned the jeans and took the pre-dripping cock out from the straining fabric.
No matter how hard Miguel tried he couldn’t hold back the unrestrained pornographic moan that escaped. He’s never felt this much lust in his life, it was almost suffocating as the hand started it unbearably slow pumping from head to base. It was as if with each stroke of the hand left Miguel more breathless than before,
Throwing his head back to the back stead’s headrest M/n's free hand took a handful of Miguel’s dark locks making him stare into e/c eyes. Miguel groaned, staring at the man he was marrying, having a kid with, and fell so deeply in love with it nearly hurt to feel him all around him.
Leaning forward M/n smirked, his voice heated, hot, and horny all for Miguel to make the man under him feel appreciated, worshiped, and valued. And that was exactly M/n planned to do, make Miguel’s walls come fully down to fuck him in ways that would make them both so exhausted the next morning they’d just stay in bed and bask in the afterglow of sex but the new found strength both parents had now for their daughter.
“¿Qué quiere papá que haga? What can I do to make him feel appreciated?”
Miguel’s mind was slipping, slipping into the pools of light headed lust. Pleasure building painfully slow in his guts, the weightless feeling of the hover taxi waiving past other hover cars only added to the feelings of his mind slipping into giving all power to the man over him.
All Miguel felt was appreciation from the man in front of him, sighing as lips trailed down his lips to his neck, the warmth wet trail left from his fiancés tongue left in its wake had Miguel craving for more of m/n.
“Ah, ¡joder! No sé”
-“please refrain from contaminating the back seat; if you proceed to do so you will be charged extra for any cleaning services that will be required”-
The automated voice sounded over the taxis inner speakers of the back seat. It sent an electric shock through Mighuels body as he made an attempt to fix himself, only for a hand to push his back against the plush seats of the Taxi. Soft swollen lips pushing against his own, M/n’s voice lustful, soft and jokingly tone all slipping through his voice as he spoke against Miguel’s slightly parted lips.
“You do know; you’ve known for months what you’ve wanted me to do to that body of yours; you just have to tell me how you want it daddy, this is all for you to feel appreciated”
M/n pulled Miguel by his shirt, closing the space between their lips in a heated kiss. Miguel moaned, letting his mind give in; opening the floodgates as Miguel’s hands ran their way up M/n hips grinding his hips up with each jerking motion the hand around his cock pumped. Pre leaking down the thick Vick onto the hand, lubing it up even more to pump faster.
The air around the lovers heated up, the smell of sex and sweat mixed together with their colones that only became stronger the more they sweated. Miguel’s mouth limply hang open his forehead resting against M/n’s chest watching his cock vanish and reappear as the hand twisted at the head making it leak even more pre, drool dripping from his mouth as he watched his cock get pumped with the hand; spit joint the pre in lubricating m/ns hand in jerking Miguel more efficiently.
“Remember Miggy we can’t make a mess”
Hooking a finger under Miguel’s chin M/n lifted his face to look at the existence of the state Miguel was in. What he saw had his own cock throb painfully at Miguel’s flushed face, his unfocused eyes, the drooling mouth that revealed his fangs that seemed like they were even losing control over their venom leaking out, Miguel’s messing hair clinging to his forehead. M/n smirked down at his blissed out minded fiancé who’s arms clung loosely on his hips.
“ w-want you inside, hmm ah”
Miguel moaned his head leaning against M/ns hand, his body was in a state of plearsureable numbness. The only thoughts going through his mind was the thought of M/n cock filling him up with is seed. In a primal part of his mindset miguel craved to be filled to the brim with M/ns kids.
“Want your cum…in me filling me”
“Oh? And why does daddy want my cum?hmm”
Twisting his hand harshly at the reddening tip of Miguel’s cock; m/n moaned watching Miguel’s body shake involuntarily with Miguel’s whines from the amount of pleasure.
Miguel couldn’t take anymore his cock,his stomachs, even his ass ached for his fiancés cock to fuck him raw and full with cum.
“I want more kids, want you t-o fill me with them ahh, carajo!”
Miguel stammered his request filled M/n with such primal desire to do just as his future husband asked. Fill him full of his cum, his kids, to get him pregnant; to give their baby girl Gabriella siblings right away.
It was a part of Miguel’s brain that had these instincts programmed into him from the desisted, it made Miguel feel nothing more than a needy animal but in a way it was part of Miguel that he couldn’t hate…not when it made sex feel so fucking good.
Yet Miguel wasn’t prepared for his pants to be yanked as far down as M/n could manage before he got sexually frustrated enough to the point he removed his hand from Miguel’s burning cock to O’Neal down in between Miguel’s legs yanking his stained jeans the rest of the way off.
Licking his lips as he stared at Miguel’s pre-covered cock to his twitching hole. Shoving his own fingers into his mouth not knowing just how deputed Miguel’s venom was;
“Don’t give me those sexy eyes, I’m not gonna risk getting paralyzed by that venom of yours again.”
Throwing his head back in frustration Miguel knew M/n was valid in his concerns last time they were lost in this kind of lust he was paralyzed for a good part of the day stuck with a raging boner.
Opening his eyes Miguel looked down at M/n who was sucking on his own fingers coating them in his spit, while his other hand grabbed ahold of Miguel’s thigh guilding it over his shoulder showing off the puckering ring of muscle that craved for him.
Feeling his face heating up to a point Miguel could only moan as fingers began their teasing taunts with each small push, a slight probe. Whines escaped Miguel’s lips as one of his hands gripped his own hair the other made its way to his beading pre cock. Only for the hand to get slapped away.
Shocked, Miguel looked down to M/n whose face was in between the two mounds of ass, his tongue pushing past the ring of muscle, loosening the inside enough for a finger to shove it’s way all the way to his knuckle.
“Amor a la mierda por favor déjame eyacular”
Miguel’s struggling voice whines his free hand reaching down to M/n hair gripping his fingers into the soft messy h/c. Pulling m/ns head closer with each brush made on his prostate. The burning pleasurable sort of pain each time a finger was added along with the tongue that still eases the ring of muscle open.
Stretching Miguel’s ass farther, the heights of Miguel’s nearly climax was at its peak, the knot that formed altightened, heightening his senses even higher than before as blood rushed to his ears the corners of his eyes started to go white with pleasure.
All stopped once the autopilot spoke once more the voice alerting them of their nearly destination in a few moments. Causing the head between Miguel’s shaking thighs to retreat, along with the tongue that Miguel had gotten so used to the warmth of inside him.
Letting out a desperate breath Miguel looked down at M/n. Whose face was just as flushed as Miguel’s as he stared back, his fingered scissoring Miguel’s still tight hole open; preparing him just the way he wanted.
All while he stroked a hand against Miguel’s neglected cock that leaked far more the more teasing M/n did.
“Look at yourself you sexy beast, being scissored and stretched with one hand while being given the best handjob with the other and still you want me. Shock I love it when you let me take care of you baby, so sexy”
Miguel’s hands clasped M/n head weakly hinting at his desperate want for their lips to mean once more. Chuckling M/n continued his assault of his fiancés ass and cock. Their lips barely brushed against the other when the hover taxi sounded;
-“destination reached! Scanning; cleaning required your holo card will be charades as such for a cleaning crew, enjoy your day”-
M/n smirked down to Miguel’s exposed body, exposed to him and him only; Miguel’s muscles that were flexed made the shirt he worse tight and cling to parts of his body that had M/n drooling himself while racking his eyes down the masterpiece of the body before him.
Miguel’s cocked twitching with the lack of attention went for his ass as it tried to pull his fingers deeper. Latching onto Miguel’s soft spot on his neck resulting in slightly taloned hands to grip his shoulder breaking the skin slightly: the pain was worth more of those sweet, addictive moans being pulled from those plump lips.
“Shock Miguel keep doing that and I might let you fuck me instead”
Miguel’s groan tugging on M/n’s suit wanting him to be in the same amount of undress he was right now. Miguel wanted him inside, fucking him raw and primal to worship his body like he knew M/n would.
“cariño, please get me into the house and you can do whatever you want with me!”
His head rolled back as M/ns fingers retreated out from his ass, with a wet sound as they pulled fully out leave his hole twitching for something to clench, to suck deep within itself.An invention M/n would soon take
“When you put it like that how can I say no”
Miguel let out a shaking breath as hands brushed up his chest all the way down to the jeans that were still down at his ankles.
“Shock I can’t stop looking at you; fucking beautiful”
Lips ghosted down Miguel’s thighs, the trail of kisses were near unbearably sweet; it had him breathless all while M/n pulled his Jeans up, his boxers covering most of Miguel’s hyper sensitive cock.
The fabric now covering him up had Miguel panting as he resisted the urge to pull the clothes off his hyper sensitive cock. The fabric brushing against his slightly exposed head had Miguel squeezing his legs together as much as he could as the two made their way into their house.
A house that already held so many memories and would hold more. A clean organized house, with modern furniture decorating the interior of the modern home. The only messy part could be spotted in the kitchen which was getting cleaned already by LYLAs drones.
Miguel’s scenes were in overdrive; the smells of both men perforated the air of the house with their colognes, and now the smell of sweat, and sex that clung to the two. The smells are becoming stronger in their bedroom. A room that houses all the smells that had Miguel's instincts go wide.
It all had Miguel’s head spinning as he turned to M/n who smirked as he threw their suits onto the floor seeing the darkening lust that poured into Miguel’s eyes just before he pulled his other half on top of him.
M/n gasped as their bodies hit the plush bed; Miguel’s face was redder than m/n had ever seen it, his hair was messy sprawling over his face and bed. His fangs catching the dimmed lights as miguel spoke his voice thick with a need to be fucked, to be filled with cum.
“Love you; want more of you”
“Yeah?”
“¡Sí, por el amor de la mierda, por favor, que me jodan!”
M/n practically ripped Miguel's clothes off leaving the far more stronger man naked and bare underneath his body. Miguel’s broad figure relaxed moaning with each light touch M/n left on his skin. Any amount of lips that licked up the sweat that ran down Miguel’s anticipating body.
M/n loved seeing Miguel so lost in the ecstasy of it all. Watching him shiver,buckle, beg underneath him seeing him finally let go of all the stress and pressure that the last few months placed on him. Now he gave in, allowing himself to feel everything all at once.
M/n took his time stripping his own close off his body, giving the desperate Miguel underneath him something to enjoy with each curse word that poured from Miguel’s lips with each piece of clothing thrown elsewhere in the room.
Miguel, sexually frustrated made a move to pull M/n down to him but it only resulted in him being flipped into his stomach. Gasping as hands gripped his hips, pulling them flushed with a straining pair of pants that covered a raging cock under eight rubbing ever so slightly against Miguel’s prepped plum ass.
“Such an impatient daddy; maybe I should punish you-“
“No!”
“I guess you're right, this day is all about you, about making you feel really loved. Is that what you want for me to shove my cock inside this needy hole?”
Miguel’s talons released from his fingers gripping the thick blanket underneath the two, the unstable fibers of the blanket resisted the tearing from Miguel’s claws. Miguel looked over his broad shoulders seeing M/n tossing his pants off the bed along with his boxers leaving them both fully naked, a fact that had Miguel pushing his ass back against the cock that now rubbed its pre leaking head between the two mounds.
Miguel arched his back as the head teased his waiting, ache hole. The heat radiating from m/n legs and cock that pressed flushed with Miguel’s body had him moaning tears of joy ran down his face with the burning pleasure rippled through his ass up to his head.
As m/n started to slowly push the head of his cock inside Miguel. Hearing M/n’s low moans against his lower back, groaning about Miguel’s tightness that clenched around the head.
“Shock, miggy your ass is pulling me in so well”
Miguel moaned loudly at the praise, taking pure bliss of feeling so fucking full of M/n’s cock. Each each raised Miguel’s moans higher and higher, the addictive burn of his ass adjusting around the cock that fox in oh so perfectly had Miguel’s rolling his hips. M/n's hands grip on Miguel’s hips tightening as he holds back to give Miguel some time to breath only for Migue to buck his ass back slamming the rest of the cock into him.
“Fuck miguel! Ah”
“sí se siente tan lleno querido, más quiero todo lo que tienes"
Miguel managed to get his arms under him, his talons gripping tighter on their blankets; the glow from the fibers resisting the tears had the dim room glowing faintly as the illuminated the two pleasure lost men.
Miguel threw his head back moaning loudly as M:n hips gave in fully to Miguel’s demands. An iron grip on Miguel’s hips would bruise the next morning from the intensity of m/ns thrusts had Miguel voice breaking mid moans. In no time m/ns cock found Miguel’s prostate ramming into the bundle of nerves repeatedly.
Electrifying pleasure after pleasure had Miguel screaming as his vision began to turn nearly white as the pleasure blinded him. His knees began to lock up the feeling of the nearly inhuman speed his fiancés thrusted into his tight ass had Miguel railing for more.
Thrusting his own hips back against m/ns the sound of skin slapping against skin echoed in their room the smell of sex and sweat became nearly as intoxicating as the pleasure. The nails in his hips trailed separating one wrapping itself around Miguel’s dripping reddening cock pumping the cock in time with his thrusts stimulating Miguel’s nerves even more. Miguel’s mouth hangs open saliva escaping his mouth that is now mixed with his venom making for a sweet but bitter taste to be a constant in his mouth.
Before Miguel had time to realize the other hand trailing threw his hair it was already to last as M/n pulled Miguel’s head back, both arms wrapped around Miguel’s body pulling the pleasure lost man to his own chest allowing lips and tongue to trail down Miguel’s neck leaving hickeys and bite marks in their wake.
Miguel’s moans turned into whimpers as the increased intensity of m/n thrusts became harder and faster the knot in Miguel’s stomachs was reaching its breaking point; Miguel’s cock was leaking an amount M/n's hand was covered in the pre.
“Ah, look down Miggy, fuck my cock is filling you good hun”
Miguel did as he was told with slight resistance from the still tight grip M/n's hands had in his hair. What he saw had Miguel nearly lose his instinct riddled mind as a bus able bulge could be seen with each harsh unforgiving thrusts.
“Go on, fill it, fill just how much I’m filling you baby; rub that cock filled stomach of yours for me.”
Miguel threw his head back as another dead-on hit to his prostate was made, his head resting against M/n shoulder. His hands trailed up to his stomachs moaning at each thrust had the bulge protruding from Miguel’s stomachs to rub against his hands.
M/n was right he was filling Miguel so good, so much filled him Miguel never wanted this to end the feeling the cocks head gave him with each thrust had Miguel’s brain want to believe it wasn’t a cock but his and M/n’s child growing inside of him. A baby bump; that a child was growing inside of Miguel.
“Shock M/n more ¡Lléname, cum dentro de mí por favor! quieres darle a Gabriella un hermano quiere a tus hijos, amor”
“Ah fuck keep t-talking like that and I’ll loose it hun”
“So close to, ah shock, shock please so close! W-anna feel you cum inside me!”
The knot that’s been building in both of the two lovers grew to its breaking point. The pain melded with the pleasure of the pressure build up had Miguel gripping M/n's ass keeping him in place the best he could while his screams of pleasure filled the room ; ropes of cum splattering all over the bed sheets and m/ns still pumping hands.
Wet skin slapping movements filled the air of the couples room; as a tear stained Miguel gasped for any amount of air he could get as his body shook only for a moan to rip be ripped out of him as his hand felt M/ns hips sputtering in a final harder thrust up into Miguel’s tightening hole; the bully Miguel felt twitching harshly against his prostate as his inside were flooded with m/ns hot seed. Made Miguel buckle his own hips into the air as yet another unexpected second orgasam hit him.
Grabbing hold of M/n's hair Miguel sighed, feeling his lover's lips soothing him. Soft lips trailing up Miguel’s neck to his jaw. His hand turning Miguel’s fucked out expression towards him peppering kisses all over Miguel’s face that scrunched up in discomfort as 5the now softened cock slipped from his cum dripping hole.
Leaving Miguel whining yet moaning at the soft attention he was receiving from M/n whose other hand rubbed what was left of Miguel’s cum on the now dirty blanket. Before stroking Miguel’s aching thighs and hips.
“I didn’t hurt you did I?”
Miguel laughed, opening his eyes to stare at his worried fiancé who’s shoulder bore more damage compared to Miguel’s soon to be bruising hips.
“You're asking me? Last I checked I’m not bleeding anywhere”
“Yeah yeah smart ass, fuck I love you so much“
Interweaving his fingers through the h/c hair Miguel breathed in m/ns scent now mostly smelling of Miguel and sex Miguel relaxed basking in their afterglow.
“Yo también te amo, m/n”
Feeling m/n face pressed into Miguel’s neck Miguel relaxed as he continued to play with his lover's hair; feeling him speak against his neck a statement that had Miguel’s chest ache with just how much he loved his man holding him.
“And I love our daughter; I’ll protect both of you the best way I can I swear, I’ll keep you both safe no matter what”
“Now you’re stealing my lines”
A chuckle tickled Miguel’s sensitive neck as they both chuckled while caressing each other's bodies, messaging out the aching muscles.
“Sure am, we deserve a normal life don't you think, a nice long vacation”
“And just how long is this vacation lasting?-“
“The rest our lives; raising our beautiful baby”
The couple intertwined their hands M/n looking down at Miguel’s ring around his finger, the joy and light feeling of finally finding the family he’s spent all his life searching for was here. Had always been here in his arms for years and now another part of their family is one her way as well.
Pulling Miguel’s hand to his lips both Miguel and M/n kissed their ringed fingers, nudging ‘em their head together as they basked in the love they held for each other and their daughter.
Nothing would change that…ever.
Part 6 final
( damn this turned out very long and angsty and soft all at the same time! Hope y’all like it!)
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lua-magic · 8 months
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Intresting Astrology facts (Vedic Astrology)
Twelfth House Venus is exalted, but do you know why?
TWELFTH House is the house of giving and charity.
Ketu is giver, hence, exalted in twelfth house
Venus is known as enemy of ketu then why both these planets exalts in twelfth house?
Because, Venus twelfth house (Untill it is not in sign of Saturn ie, 10 and 11) knows how to give
Venus exaltation in the house of Jupiter that is twelfth house, shows the more you spend your money spiritually ie to help others, your Venus will improve.
So, basic rule of universe is what you give more to others you will get it, so if you want to improve your twelfth house, which is house of bed pleasure, foreign travel, investments, sleep, learn to give others, your twelfth house will improve..
Venus Ketu conjunction is always seen as negative combination, but it is one of the most spiritual combination, only if you see money as spiritual wealth and not Material wealth.
Ketu is spiritual planet, and detachment, be detached from money, spend your money first to help, ketu will bless you.
If you have Venus ketu conjunction and you get influenced easily when you see other's money you are triggering your ketu and ketu will become negative. Always be grateful for your money, and see it spiritually, more spiritual you become regards to money matters more ketu bless you, so whenever you spend your money, bless your money.
Arigato” is Japanese for “Thank you”. It describes the inflow and outflow of cash as a necessary circulation in our life.
What is this technique?( This technique is exclusively for Venus ketu conjunction.)
The technique is extremely simple. Whenever you have an inflow of money, you accept with love and gratitude no matter how small or big the amount is. And you do the same while spending money, that is, spending money with an open heart and gratefulness. The appreciation for the outflow and inflow of cash is as simple as saying a “Thank you”.
Ketu is also your past life pending karma, so don't be sad when someone takes your money, he/she is just finishing past life debt that you took.
Venus Rahu conjunction should always keep their Rahu good, then you get good money, Rahu is foreign land, import export, thinking big.
But, if you get into lust, illicit relationship, multiple relationship, you will trigger your Rahu and Rahu will act negative.
Rahu in vedic astrology are cleaning workers, one of the best remedy of Rahu is donate to cleaning workers.
Venus Mars conjunction has super attractive body 👁️ 👅.
Venus-Mars conjunction should invest money on fertile agriculture lands or atleast in real-estate, Venus is Money and also sperm, Mars is land, Venus Mars is fertile lands.
Whichever house Venus sits in you will get money when you do work related to house,
First house Venus - Work on yourself, your personality, your identity.
Second house Venus - Work on speech, work with Family, cooking, Astrology.
Third house Venus - Work with siblings, work on your skills, communication.
In male's chart Venus third house gets you wife who has Martian quality, that is fighting skill, she will fight and protect you
Fourth house venus- When ever Venus is conjucted with moon, one best remedy is change your place, your birth place your Venus will improve, fourth house is house, work related to decoration of house is good.
In male's chart Venus moon conjunction attracts females who are good in decorations and cleaning of house.
(Rest of the house I will continue in my next blog.)
Afflicted Venus or debilitated Venus also shows physical or sexual abuse
Venus eighth house if afflicted gives you sexual traumas..
Second house and eighth house Venus are great with Astrology and occult.
Treat Money as spiritual wealth your Venus will improve.
Twelfth house is always what you give.
Eighth house is what you have to let go.
Sixth house is what you fight for.
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covid-safer-hotties · 10 days
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SARS-CoV-2 impairs male fertility by targeting semen quality and testosterone level: A systematic review and meta-analysis - Published Sept 9, 2024
Abstract Background Since the discovery of COVID-19 in December 2019, the novel virus has spread globally causing significant medical and socio-economic burden. Although the pandemic has been curtailed, the virus and its attendant complication live on. A major global concern is its adverse impact on male fertility.
Aim This study was aimed to give an up to date and robust data regarding the effect of COVID-19 on semen variables and male reproductive hormones.
Materials and methods Literature search was performed according to the recommendations of PRISMA. Out of the 852 studies collected, only 40 were eligible for inclusion in assessing the effect SARS-CoV-2 exerts on semen quality and androgens. More so, a SWOT analysis was conducted.
Results The present study demonstrated that SARS-CoV-2 significantly reduced ejaculate volume, sperm count, concentration, viability, normal morphology, and total and progressive motility. Furthermore, SARS-CoV-2 led to a reduction in circulating testosterone level, but a rise in oestrogen, prolactin, and luteinizing hormone levels. These findings were associated with a decline in testosterone/luteinizing hormone ratio.
Conclusions The current study provides compelling evidence that SARS-CoV-2 may lower male fertility by reducing semen quality through a hormone-dependent mechanism; reduction in testosterone level and increase in oestrogen and prolactin levels.
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squishyowl · 3 months
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As a a biology major, I might say that Magnus, as somebody who has bird-like features, would have a cloaca! (Also I apologize for my info dumping, it's a headcanon that I find interesting and would like to share <3)
Most male birds use their cloaca, a multi-purpose orifice used for both digestive excretion and reproduction, to mate. Species of birds that have a penis include ducks, geese, and swans, large flightless birds such as ostriches and emus, and tinamous, a family of ground-dwelling birds closely related to the ratites.
Ducks and geese, again, are famous for their extra-long penises (😭). For example, when extended, the usually coiled penis of the Argentine lake duck is longer than the bird itself! Most birds can't really brag, Males in 97 percent of bird species have tiny penises or lack them entirely. Instead, they shoot sperm into a female bird's body through the cloaca
Fun fact! Some birds have feathers on their penis, while others are covered in spines and small filaments. (which, in the context of my headcanon, I find really fucking hilarious)
During the rutting cycle, as seasonal temperatures, light levels and food availability signal the start of the mating season the cloaca swells and expands. Once breeding is done, the cloaca and other reproductive organs shrink to minimise weight for flying and migration.
In this case, Magnus either has a VERY long penis or no penis at all. In the latter example, he'll especially have to perform anal sex in order to impregnate his partner
(also, biologically speaking, Leman Russ definitely has knot)
for my own personal sanity im chosing to believe he has a generally human-looking schmeat just with some vague bird-like qualities, such as longer length and the ability to retract it. feathers around the base/crotch to hide it when retracted ain't a bad idea either (mans does not wear any pants as a daemon so he's gotta have a way to hide it)
also extreme agree on Leman Russ having a knot, if Horus' geneseed were based off of wolves I'd say the same for him too cause of the canon compliant breeding kink
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midnight-omega · 1 year
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Anatomy hc
Okiii ur girl spent most of last night trying to figure some things out and draw some diagrams fr
This post focuses on the reproductive anatomy of my omegaverse. I'm gonna go through each of the 6 gender/dynamic combinations and give a little info about how I think it all works :> like everything else this varies from person to person so if this isn't ur thing no worries! If this is ur thing feel free to use it! But if you use my diagrams I'd appreciate it if you credited me be i spent a long time on them 😔
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I also want to link this very in depth explanation because I did take a lot of inspiration from it for my male omegas! I adore this concept for them and I'll be using it going forward. The author talks about a lot more tho some of which imma steal some of which Im not :))
Okay lets get into it fr, be warned there are my messy diagrams of all kinds of private bits under the cut. Also if tumblr kills the quality im so sorry fr :((
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Male Alpha
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🌕 Let's start with our boys here.
🌕 Honestly they're pretty straightforward! There's not too many crazy anatomy changes here. They function pretty much the same as irl amab anatomy does.
🌕 They have a penis and external testes
🌕 They have a prostrate that can be stimulated via anal penetration
🌕 Male alphas tend to be on the bigger side concerning length/girth but this varies from person to person
🌕 Now, the defining characteristic of a male alpha is their knot. Only alphas have a knot!
🌕 The knot is soft tissue that expands during orgasm. This "locks" the penis into the vagina in order to facilitate conception. In simple terms, sperm stuck inside better change pregananant
🌕 The knot typically stays expanded for about 20min after orgasm, but this can vary. Any longer than an hour though, can be cause for concern
🌕 The male alpha usually has a larger knot than a female alpha and experiences higher chances of successfully "tying" (tying here meaning the knot actually gets stuck in the receiver)
🌕 An alpha can knot outside of rut, but these knots may be smaller or not fully expanded since they're lacking the overproduction of hormones that rut creates
🌕 A deflated knot is still visible as a ring of much softer tissue than the rest of the shaft
Female Alpha
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🌕 oh boy, oh god, mother mary save us all
🌕 This one was so HARD to figure out fr... let me get into this
🌕 I've always liked the idea of a female alpha having a hidden penis best. One that's concealed where the clit ought to be but expands and pops out during rut or when aroused. I like this one best bc I'm not a super big fan of the anatomy set up of having a vulva and dick and balls all at once, and anatomically I never understood like... the concept of the clit swells a lil and thats the knot bc... penetrate how?? I also just don't like pregnant female alphas much! To me alphas impregnate only not carry
🌕 So hidden penis was my favorite option !
🌕 But once I started drawing out the diagram I immediately had problems placing the sheathed penis inside the body
🌕 My biggest issues were the bladder and pubic bone. The bladder I can move around easy enough, especially since female and male anatomy have it in slightly different positions anyway
🌕 But what was fucking me up was that damn bone
🌕 If we want to replace the clit with a penis the penis is going to need to run straight through that bone. The pubic bone in female anatomy sits right above the clit basically. In male anatomy its a tad higher up but even moving it up it would still be in the way of the penis
🌕 I could continue to move the bone or do away with it but then we compromise the human shape of the female alpha. The rest of the dynamics would look human in the hips and pelvis but female alpha she'd be.. little fucked up. Not to mention I'm sure there's some other wild medical consequence of removing or moving the pubic bone that I'm not aware of
🌕 So... we can't put the sheathed penis exactly where the clit is
🌕 I could put it where the vagina is, but then that eliminates the vagina entirely and makes female alphas unable to have penetrative sex and tbh I'm not into that give her a gspot yk?
🌕 I could move the urethra around, like push it forward towards the clit even more and push the vaginal opening backwards, or even combine the vagina and anus like the male omega but I wasn't a fan of that either. It makes her feel to male omega-y and less unique to me
🌕 Furthermore like... vaginas are low. Like lower than u think, clits are a little lower too. And penises are so high! So.. having a penis come out so low between your legs wouldn't that make penetrating kinda hard unless you had a crazy long horse cock or smth.
🌕 So I ended up keeping the penis sheathed like I wanted, but I moved it up
🌕 The penis head is a little above where a clit would sit but I still removed the clit from her anatomy
🌕 To avoid the bone I had to put the penis above it. This isn't super crazy since the vans deferens also comes down over the bone, but it is a little awkward because this isn't a little tube this is a PENIS. This is a whole long cord of tissue and blood vessels here and I'm not giving her a small flat cock to compensate she doesn't deserve that
🌕 So, her muscle, fat, skin, and what have you is gonna have to push out to make room for the penis sitting above the bone.
🌕 Insert female alpha sheath bulge >:))
🌕 tbh I think giving her a bit of a bump is pretty hot so I'm satisfied!
🌕 However bc its sitting right over a bone any pressure applied to it is going to be uncomfortable or even painful for her
🌕 So... ig if you wanna kick a female alpha in the nuts aim for her sheath fr
🌕 So then I was good for awhile, I had placed the penis in the body in a way that satisfied me and kept the vagina intact
🌕 But okay now the penis has to come out
🌕 The female alpha cock still sits lower than the male one, so we have to do a little more bending to get it to flip up in proper penis formation
🌕 No problem, I'll just give the female a longer base after the knot and said base will be way more bendy than a real penis np np
🌕 Okay but... if we have a noodle base how is the erection staying erect and not just becoming a top heavy string of stuck blood that flops tf over
🌕 Insert what I did with the labia
🌕 I want female alphas to enjoy vaginal sex if they want to mostly for kinky reasons yk but its my world so!
🌕 But this means that I don't really wanna touch the labia around the vagina, they should still get looser during arousal they should still be fun to play with yada yada yada
🌕 But the penis needs something to lock it upright. So I split the labia into even more parts.
🌕 On irl afab anatomy theres the inner and outer labia and that's that. On the female alpha tho I had to get creative. I gave her her inner and outer labia that would function normally
🌕 Then I gave her another set around the exit of her sheath. I called them! The penile labia for lack of creativity and anatomical knowledge! Unlike the outer and inner labia around the vagina, these ones stiffen and lock up during arousal after the penis has been unleashed. This keeps it out and helps it stand!
🌕 I also gave her a middle labia. This is an extremely tough piece of muscle that separates her upper and lower sets of lips. The middle labia supports our bendy base even more and tends to get engorged and may even expand a little to support the weight of the cock and knot
🌕 This isn't fool proof by ANY means and I'm sure ppl who know anatomy better than me have a million issues rn but yk what? This makes sense to me and took me awhile to figure it out fr so I'm content
🌕 Now... I gave her a uterus-like structure and still called it "uterus" for lack of better term. this is not a functioning uterus so female alphas cannot conceive
🌕 But in this model I have this uterus act more like a muscle that helps push the penis out of the sheath. Believable? Idk but its chill with me
🌕 The female knot is generally a littler smaller than the male knot because it's gotta fit in the body
🌕 The knot here doesn't even begin to expand until the penis is unsheathed, whereas in males it may puff up slightly on initial arousal
🌕 Since I did not give her balls, her testes are inside the body where the ovaries would typically be
🌕 insert the part where I tell you alpha sperm does not need to be cool. It can survive higher temperatures which also makes sense considering omegas practically have heat strokes during heat, the sperm would need to be a little tougher.
🌕 But then why do males have balls? I got u fam ! Bc while they can survive in warmer temperatures that does not mean they thrive there. The healthiest swimmers are still kept a little cooler. Female alphas may be less fertile even because of this which could be some fun plot points bc i love female alphas pls write them more
🌕 That was so LONG but I think that's it for her
Male Beta
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🌙 The male beta doesn't really have anything super atypical from irl amab bodies.
🌙 The penis of a beta tends to be a lil smaller than an alpha's but bigger than an omegas, but again this isn't always the case!
🌙 We do have a prostate for fun anal times if desired
🌙 Beta sperm is not as heat resistant as alpha sperm. They can impregnate other betas just fine but may struggle with an omega in heat. It's suggested that b/o couples try conceiving outside of heat with the help of fertility experts :>
🌙 Male betas cannot conceive, they have no uterus or vagina
🌙 Betas do not knot!
Female Beta
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🌙 Again, not a lot of differences to talk about here, typical afab anatomy
🌙 It is worth noting that in my verse I am not giving female betas periods bc thats mean
🌙 For this reason their endometrium is thinner than ours so the body can reabsorb it without a true heat easier
🌙 I'll also say that beta eggs are just built different for this thinner endometrium
🌙 usually you need a certain thickness for the egg to embed properly to the uterine wall, but imma say that for whatever reason beta eggs are totally chill with a thin lining. They have a better grip or smth ig!
🌙 This allows my girls to get pregnant without an extra added issue due to my silly anatomy choices
🌙 It also makes her different from the female omega which I'll talk about later :))
Male Omega
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🌑 Okay ya'll get ready for shitshow number two
🌑 actually the male omega wasn't as bad to figure out mostly bc I stole the idea of the epivagina from the author I linked above the cut!!
🌑 I'll sum up if you don't want to read through the link (you should tho it's really interesting stuff you might wanna use in ur own verse!)
🌑 So like the female alpha there are depictions I don't like when it comes to the male omega. I don't like them not having a uterus and just being... a guy? Like having nothing about them that makes them different than a male beta. Also, like how I said I don't like pregnant alphas, I don't like omegas that can impregnate.
🌑 I'm also not a fan of not giving them a penis and having them only have a vagina and uterus. What makes the two omega genders different then? Breasts? Not a fan tbh considering I like my male omegas to breastfeed with their lil pregnancy boobies (cancer in venus I like boobies and lactation not sorry)
🌑 Basically I want my mpreg and I want my penis too
🌑 So, like the female alpha, we have to give them both parts.
🌑 Since there's not a ton of room between the balls and the anus (the taint is only so big yall) I'm not a fan of just giving them a vulva here
🌑 I'm also not a big fan of the birth canal that develops from the taint when pregnant just bc it doesn't make sense to me that the body just forms and unforms a hole that they have to push out a baby the size of a small melon through. Like in that case pregnancy must be excruciatingly painful on top of pregnancy already being painful and hard
🌑 So... butt babies. Except not quite
🌑 The popular option is the cloaca but... I have issues with that too
🌑 If you read the chapter on male omegas on the ao3 link you can see why. A short cloaca definitely results in poop in the vagina. I don't think I need to explain why poop in the vagina is like the worst thing. As the author points out it also makes it difficult for fun oral time just bc the amount of infections you can get from... constant ass licking/fucking especially bc I haven't seen any male omegas telling their alphas omg wait i need to shower, shit, and have an enema first
🌑 The long cloaca can work ig but then the penis never enters the vagina and thats just not fun. The male omega would never be able to have vaginal sex fr :((
🌑 So I'm going with what the author made up! The epivagina!
🌑 The epivagina is a strong valve-like muscle kinda like the middle labia in alpha females.
🌑 During non horny times the epivagina remains positioned in a way that closes off the vaginal opening. No penetration without literal tearing can take place with it closed. The anus is open and free for poop!
🌑 During heat and arousal the epivagina switches the other way opening the vagina and closing the anus so the opposite is true
🌑 You do not have to be in heat for the vagina to open btw! Just turned on
🌑 During birth we can just assume the sphincters and muscles around this anus and vagina were built for stretching, though it might be recommend for male omegas to anal train a bit to get all our muscles ready for it (there are literally butt plugs the size of a child's head so we can train out asses a lil)
🌑 Now the drawback to this would be that... you cannot have anal with a male omega if he's turned on. Tbh that's okay with me since i'm not really into anal anyway! If it's not okay with u then.. idk change it to fit ur kink babe im not stopping u
🌑 It also kinda acts as a rape defense too in a way.... like a duck if we're not turned on good luck entering the vagina. ofc... the exception to this is heat in heat it's p much always open unless we need to shit rn so ig vaginal rape protection in heat isn't a thing but it's neat outside of heat
🌑 Male omegas do produce very small amounts of sperm but they're such sad little boys it's basically impossible to get pregnant from them. Most of them have clear orgasms if they come from their cocks at all.
🌑 I did raise their balls a bit back into the body. We're still descended but not... exactly the whole way if that makes sense. Our sperm just isn't as cool this way and it's not heat resistant fr!
🌑 Bc omegas get so hot during their heats this can also decrease or fully kill off any remaining sperm production.
🌑 Technically this way you can still get pregnant by a male omega if you're a female beta/omega but.... bc its my verse and I don't really want that I'm gonna say it happens like once in a century it is not really a thing
🌑 The penis here is smaller than anyone else's, but not as small as you'd think. I'm not going the whole micropenis route with them you can still be satisfied through penetration with my male omegas!
🌑 Like the author, I also like the concept of giving them a prostate and an internal clit >:))
🌑 no real reason other than 3 ways for my boys to orgasm and I like it
Female Omega
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🌑 Pretty similar to the female beta, not too much difference from irl afab anatomy
🌑 The biggest difference between a female beta and female omega are:
🌑 Slick production (beta's do not produce slick)
🌑 The endometrium
🌑 I gave my beta's a thinner one so their bodies can absorb it and we can avoid menstruation!
🌑 Well in female omegas the endometrium is thicker, about the same as the average one irl or maybe even a little thicker than that.
🌑 Her eggs just aren't as good as gripping just like irl fr, so we need a lot of cushion for them
🌑 especially since female omegas tend to release more than one egg a cycle (2-4 is normal) so if we're all embedding we need more room to do it
🌑 A female omega also can reabsorb her endometrium no worries I am not giving her a period either
🌑 Instead I'm going to say that heat has 3 phases. Pre heat where we get ready for ovulation that lasts about 3-4 days, heat heat which lasts about 1-2 days or less. This is when we are fertile we need to get pregnant NOW, and then post heat which lasts about 3 days where our body temperature is still extremely high and we're still horny and feverous but the egg has passed alas. Its during post heat that we reabsorb and break down the endometrium. Sometimes we might see a little blood a lil spotting yk, but for the most part our heat stroke helps us absorb it idc if that's unreasonable its what imma say
🌑 The term heat usually includes heat and post heat but not pre heat (I mean you get off work for heat and post heat and we use the term heat as a collective to include that 5 or so days but this doesn't include the pre heat) but i'll do a different post for heats later !
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I think thats everything if you survived all that thank you for indulging me fr! Feel free to pop in my askbox if you wanna talk about smth and like I said in the beginning feel free to steal but pls credit my diagrams if u use them :))
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So another Twilight rant after a very very long time.
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Do you think Aro knows how to fight? Personally I feel like he does. If we go by movie canon. And also before Chelsea came around and while he was still forming the coven he had to break up some fights.
And also, the Volturi guards had to be better fighters than the cullens let's be real. There's no way Demetri got taken out. And ESPECIALLY Caius. That was ridiculous! I'm still so mad. The executioner, the man who battled werewolves being taken out so easily is stupid.
Another thing is that Caius is portrayed as being an angry, hateful person. He's the classic one dimensional villain with zero personality. He's got to have some good sides? Even Aro has his positive qualities.
Also, the entire vampires don't mentally change? Yeah I hate it. Look at the cullens. Especially Jasper. That one has the most questionable past as a human....but I'm pretty sure he's no longer the same. What I'm understanding is vampires in the Twilight universe cannot experience emotional or mental growth? There are vampires who had no respect for human life before but later learn to live a different lifestyle. That's emotional and mental growth in a way. The Romanian coven for example are supposed to have so much rage...but they don't seem to have much? Honestly, If vampire males can have sperm they can develop new braincells lmao.
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mindblowingscience · 8 months
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In humans, male fertility and sperm fitness decline with age, but scientists have made the surprising discovery that this pattern is not consistent in other animals. The findings have been published in the journal Nature Communications. The team, led by the University of Oxford, assessed the results of 379 studies which covered a wide range of animals, including mammals, insects, birds, and fish. This found that advancing age seemed to have no impact on ejaculate size, number of sperm, sperm motility, or sperm viability.
Continue Reading.
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victimsofyaoipoll · 1 year
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Round 1
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Propaganda Under Cut
Safu
I am adding my vote because the yaoi may be canon in this one but Safu is still Shion's best friend and the way ppl leave her out of stuff sucks ass. Her character development was the ONE thing the anime had over the novels and manga but even the anime only fans won't look at her. She literally said "I want your sperm" out loud with her mouth in a train station to ask her best friend to date her. Weird girl extraordinaire who became bee jesus people need to stop sleeping on her for the guys.
She has a crush on Shion and makes it quite known She also asked for Shion's semen once
Neurodivergent queen! She autismed her way through puberty so hard, she thought her feelings for the protagonist Shion were purely sexual, until she spent time away from him to grow as a person
Annabeth Chase
I feel like fandom is kinda split on her with percabeth shippers loving her but any m/m shipper I've seen does not like her, really. She is my bae tho <3
Percabeth antis grind my gears so much because they never hate Percy, nono, even though he's arguably done more questionable stuff than Annabeth. Not everyone who hates her is doing so because of a mlm ship— the Perachel stans claim that Annabeth is a misogynist. However, basically everyone that isn't trying to ship her boyfriend with Rachel is trying to ship him with Jason, Nico, or her old friend Luke. They make her out to be this horrible abusive girlboss(derogatory) that she's simply... not. She doesn't insult Percy for having ADHD just because she's highly intelligent. She doesn't physically abuse him, and doesn't lay a finger on him outside of training. She's really devoted to him in a non-anti-feminist way. They just hate her for 'getting in the way' of Nico's convoluted attraction to Percy, or Jason's close friendship with him, or Luke's rivalry with him. But those relationships all flourish the way they were intended by the author: non-romantically. It's not Annabeth's fault for being intelligent or capable or jokingly snide or determined or any of those non-stereotypically-feminine qualities. She's just out here existing and people hate her for not being a man. Sorry for the rant.
She's canonically in a relationship with Percy Jackson for most of the books they're in, but he often gets paired in canon with other male characters, such as Nico di Angelo or Jason Grace. In fan fiction (especially yaoi focused ones) she's characterized as being a stuck up know it all, but she gets into plenty of shenanigans in canon and can be pretty goofy and sweet!
I think I may have accidently used fanart for Annabeth's picture, if you have official art of her, send it in!
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kteezy997 · 2 years
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be my baby daddy-part one// T.C.
warnings: brief mention of male anatomy
it was time.
you were in your mid-twenties. everyone you knew was having a kid or already had one or more. baby fever had been through the roof for you the last year or so. you didn't have a husband or boyfriend, and didn't see that changing anytime soon, so you decided to just go for it and have a child on your own.
but there was a slight technicality. you needed sperm to make a baby. other than going to a sperm bank and paying for a sample from a total stranger, you had another idea.
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there was no better specimen to reproduce with than Timothee Chalamet. now, you two were friends, and had been for years. you crushed on him in the shadows, believing that he'd never been interested in you. you were fine with that, and happy to have him in your life as friend, rather than not at all. you never risked your friendship by telling him how you really felt.
time, and seeing him with a handful of girlfriends and random one-night stands helped the feelings fade a little bit over time. the feelings, though still present to this day, weren't as strong as they once were. thankfully so, because you didn't want anything to get in the way of what you wanted to ask of Timmy.
"Wait, what??!!" he asked you, total off-guard look on his face and eyebrows scrunched as he looked at you like you were losing your mind.
you softened your voice, "Can I use your sperm to have a baby?" his eyes widened as your words fully sunk into his brain. you saw him swallow a lump in his throat out of nervousness. "Okay, hear me out. I've thought about this a lot, and rather than getting it from some stranger, I'd see if you would have it in your heart to help me?"
"More like...in my balls?"
"Timmy, I'm serious here."
"I know, I know." he cleared his throat and leaned back in his chair and got comfortable before he said, "Okay, go on."
"You're one of my best friends. You're smart and kind and fun to be around. Not to mention extremely talented and handsome, of course." you hoped he didn't see you blush when you spoke. "I would just love for my future child to have those amazing qualities."
"That's very flattering, y/n. I just can't believe this, really." He shook his head and brought his hand to his chin, just fumbling idly.
"Just know that, if we do this, I don't expect anything more from you. You do not have to do anything for the baby. That's not why I chose you. I would never expect a relationship between you and me or for you to be a father to the kid, nothing like that. I just want to have a baby."
"But y/n you're beautiful, you're amazing, you could have any guy you want." Timmy said, his tone was that of a sincere, caring friend. He leaned forward and crossed his arms on the table.
"Where is he though?" you asked, looking at Timmy, but talking into the void. "I don't want a man. I've been through enough relationships; I just want to be a mother. I feel like it's time for me." you insisted, wanting him to realize how deeply you've thought about this.
He nodded, his hand back on his chin, his fingers softly rubbing his jawline. "Okay," he cleared his throat, "just let me think about it."
"Of course," you said, touching his other hand that lay on the table, "take all the time you need to, and thank you for even thinking about it, for considering it." You smiled, "You're a good friend, Timmy."
He gently gripped your hand back in response and gave you a soft smile.
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follow-up-news · 27 days
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Scientists have long considered that the world’s most common sexually transmitted infection, human papillomavirus, or HPV, may be a driver of infertility. Most research about HPV’s potential impact on fertility has focused on women. But in recent years, researchers have increasingly expanded their focus to include the infection’s association with male fertility. A new study from Argentinian researchers has found that the strains of HPV considered high risk because of their links to cancer were not only more common than low-risk strains in a small study population of men, they also appeared to pose a greater threat to sperm quality.
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shesay · 2 months
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Males who literally have a shorter life span than women have children in their 60s and 70s and some even 80s and there's no geriatric paternity or whatever even tho the age of the male's sperm is v important and has alot 2 do w illnesses etc and there's barely any talk abt not socially and not rly medically too 4 ex when a doctor hears that his patient is a 40yo and pregnant they start telling her abt the dangers of "geriatric pregnancy" but doesn't bat an eye at her 50yo husband even tho The quality of semen decreases with aging but u never rly hear abt it funny that
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mariacallous · 9 months
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Vasectomies are on the rise, but not all men are ready to commit to a permanent form of birth control. While the surgery can sometimes be reversed, it's expensive and doesn’t always work. What if there was another option?
Virginia-based biotech company Contraline is testing a new type of male contraceptive akin to a vasectomy but made to be fully reversible. Today, the company announced that surgeons in Australia have safely performed the procedure on 23 men in an early-stage trial.
The approach uses a soft, water-based substance called a hydrogel that’s injected into the vas deferens—the pair of tubes in the male reproductive tract that transport mature sperm. Within 30 days of being inserted, the gel led to a more than 99 percent reduction in the number of moving sperm, according to the company. No serious side effects have been reported.
Kevin Eisenfrats, cofounder and CEO of Contraline, says it’s like an IUD for men. “Right now, there is nothing out there that’s long-lasting and reversible for men,” he says. “This is made for people who are not ready to have kids, are spacing out having kids, or think they are done having kids but maybe not ready for that permanent option.”
In a vasectomy, the vas deferens are cut and sealed so that sperm can’t travel from the testicles to the urethra, the tube inside the penis.
Contraline’s method involves making a small piercing in the scrotum and using a handheld injector to push the hydrogel through a catheter that’s connected to the vas deferens. The catheter is then taken out, and the puncture heals on its own.
Once injected, the hydrogel is meant to block sperm from getting into semen. Eisenfrats likens the gel to a coffee filter, where sperm are the coffee grounds. Sperm can’t get through the filter, but semen, a liquid, can still pass through.
Men in the trial ranged from age 25 to 65 and were placed into two groups that received different amounts of hydrogel: a lower volume and a higher one. Implanting the gel took about 20 minutes and was done under local anesthesia, unless someone chose to be sedated instead.
Eisenfrats says sperm concentration and movement in the men are comparable to levels seen with a vasectomy. “We’re seeing that this is working.”
The purpose of the current trial is to assess the gel’s safety and longevity, not how well it prevents pregnancy. Participants were asked to use a back-up form of birth control while being enrolled in the trial.
The gel is designed to dissolve at the end of its lifetime, so the men will be followed for two years to determine how long it takes for that to happen. Eisenfrats says the goal is to have a product that lasts one to two years.
But men might want to restore their fertility before that time frame, so Contraline wants to show that it can safely reverse the procedure. The company has tested the reversibility of the gel in dogs, showing that sperm counts and sperm quality rebounded after removing the gel. It plans to launch a second trial this year to test the on-demand reversibility in people. Only men who said they do not want to have children were included in the initial trial.
While the study is small, Heather Vahdat, executive director of the Male Contraceptive Initiative, a nonprofit based in North Carolina, is encouraged by the safety profile so far. Her organization funds research into nonhormonal male birth control and has contributed funding to Contraline. “Reversibility seems very feasible,” she says.
The nonprofit Parsemus Foundation has been researching a similar gel, called Vasalgel, for several years, but has faced delays getting it to human trials. The San Francisco-based health organization partnered with a biotech company, NEXT Life Sciences, in 2022 to further develop Vasalgel. In a 2017 paper, researchers with the foundation showed that Vasalgel could be flushed out in rabbits with an injection of baking soda. Sperm flow returned in the animals after reversal.
“These are not complex components in these polymers. They’re pretty well characterized, and we know how they behave,” Vahdat says.
But any medical procedure could cause side effects or complications. Raevti Bole, a urologist specializing in men’s health at the Cleveland Clinic who’s not involved in the trial, says an injection into the vas deferens could come with a risk of skin infection, mild discomfort, or minor bruising, she says.
And there are still unknowns about the gel itself. While hydrogels are biocompatible and generally safe, Bole says she would want to know if Contraline’s product could cause permanent scarring or changes to the vas deferens and whether repeat injections could be done safely.
One practical consideration is how doctors will monitor patients to make sure that the gel is still working. “Even if the risk of pregnancy is low, I would want to know the risk to counsel my patients and allow them to compare their options,” Bole says.
Contraline’s gel is still years from becoming commercially available. The company will need to conduct trials of hundreds of men and their female partners to test its efficacy in preventing pregnancy. Eisenfrats says the company aims to launch a larger trial in the US in the next few years.
Meanwhile, there are other forms of male birth control in the pipeline. The US National Institutes of Health and the Population Council, an international nonprofit focused on health and social sciences, are testing a hormone-based gel that men apply daily to their shoulders to block sperm production. And in December, a small trial launched in the UK to test a hormone-free contraceptive pill developed by YourChoice Therapeutics. It prevents sperm production by blocking access to vitamin A.
YourChoice and Contraline are avoiding hormones because they tend to produce unpleasant side effects. A previous trial of an injectable hormonal contraceptive for men was stopped early when a safety monitoring board found a high number of adverse events, including acne, mood disorders, increased sexual drive, and muscle pain. The rate of side effects was high compared to what women typically experience while on hormonal birth control.
There’s evidence that men are interested in trying new types of contraception. In a US survey conducted in 2017, the Male Contraceptive Initiative found that 85 percent of the 1,500 male respondents aged 18 to 44 were interested in preventing their partner from getting pregnant.
“Men want to step up. They’re realizing that their partners have all these effects from birth control,” Eisenfrats says. “They need more options to take charge of their reproduction.”
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thoughtlessarse · 11 days
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Environmental factors like pollution contribute to declining fertility in both men and women. A recent study further investigated this issue and discovered that while long-term exposure to particulate matter from air pollution adversely affects male fertility, noise pollution poses a significant threat to female reproductive health in women over 35. According to estimates, one in seven couples worldwide has difficulty conceiving. Although studies have shown that long-term exposure to particulate matter affects sperm quality, the impact on the likelihood of conceiving was not clear. Also, studies have not investigated how noise pollution affects fertility in men and women. To bridge the gap, researchers in the latest study analyzed national registry data on infertility rates among couples living in Denmark from 2000 to 2017. They focused on a substantial sample of 526,056 men and 377,850 women, aged 30–45, who had fewer than two children and were either cohabiting or married. These couples were specifically chosen to include a high proportion of individuals actively trying to conceive. The results, after adjusting for various factors, revealed that men aged 30-45 who had higher levels of exposure to PM2.5 particulate matter over five years faced a 24% increased risk of infertility. However, PM2.5 exposure was not linked to infertility in women.
continue reading
PM2.5 exposure in women may not impact their fertility, but it will affect any baby in the womb.
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todaysbug · 1 year
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October 10th, 2023
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Ragworm (Hediste diversicolor)
Phylum: Annelids
Distribution: Native to the north-east Atlantic, from the Baltic and North seas to the Azores and Mediterranean seas. Also found in regions of the north-west Atlantic, such as the gulfs of Maine and St Lawrence, and Cobscook bay.
Habitat: Benthic; sand or mud of beaches and estuaries in intertidal zones, including areas of low salinity.
Diet: Varied and adaptable. Predator and general scavenger; feeds mainly on phytoplankton, zooplankton, diatoms and bacteria, as well as detritus, feces and aquatic plants.
Description: Ragworms are polychate worms in the Nereidae family. At maturity, they can reach up to 10 centimetres in length (4 inches) with up to 120 segments. they swim along the sea floor using the bristly parapodia found on either side of each segment.
Ragworms create U-shaped burrows in soft substrates, then creates a water current in order to draw in particles, which are trapped in a mucus net it sets at the entrance of the burrow. If there are no available particles to trap, ragworms will emerge from their homes and hunt for small invertebrates. They're also one of the few animals known to garden; they will draw cordgrass seeds into their burrows and allow them to sprout in order to produce their own food.
The name diversicolor stems from the fact that, as the breeding season approaches, the ragworm's color will shift from brown to green; males, usually indistinguishable from females, turn a bright green, while the females' dorsal surface takes on a dull green coloration. During the mating season, the male will approach a female's burrow and release pheromones, then will release sperm at the entrance of the female's burrow. She will then draw in the sperm using a water current. After spawning, both the male and female die.
The ragworm is a model laboratory animal for research, as well as to evaluate sediment quality. It is also commonly used as bait for sea fishing.
(first picture and video by me, second by Eric A. Lazo-Wasem)
Video of a ragworm swimming under the microscope under the cut!
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