#plaquenil tablet

[theworldrewritten]

coping with chronic illness: a guide in the making

Firstly, just a reminder that everyone experiences chronic illness & disability differently, even if they have the same diagnosis! This is what works for me, for my diagnoses and severity levels. I am quite fortunate that despite the seriousness of my diagnoses, I am still at a medium impact level. They affect my daily life, but I am still mobile and not overly restricted in the activities/etc that I'm able to participate in, and my coping mechanisms reflect that.

This list includes both prescription medications and over-the-counter stuff as well as daily life-hacks. Again, this is just what works for me - always consult with your doctor or care team before trying any of the meds listed here.

Things that help with frequent migraines:

Having multiple ice packs, ideally the type that double as eye masks or go over your head (search 'migraine ice cap' on amazon, it should come up). My first point of call for headaches of all severity levels.

900mg prescription aspirin. Take it at the start of a migraine. If you find this does pretty much nothing (or helps to the same amount as typical pain medication), then switch to Relpax 40mg.

Smart plugs for your bedroom lights, so you can control them from your phone. Excellent for when you can't get up to turn them off without feeling nauseous/utterly horrible. This is helpful for a lot of different types of chronic illness, I've found

While black-out curtains are nice, I personally prefer investing in a good padded sleep eye mask. I prefer having the option to put it on/off as needed without having to leave my bed. Plus, it's not all or nothing the way it would be w/blackout curtains, as there's still small amounts of ambient light seeping through the normal blinds. (Also helpful for people coming in to check on you, so you won't be disturbed by an opening door)

Stuffed animals. Sometimes even the noise of someone else being in the same room can get too much (even if not sensory wise but just mentally overwhelming, when all of your energy is taken by dealing with the migraine). Stuffed animals are my first port of call for comfort

Iced coffee. This one is a point of contention between me and my other migraine having friends, but I stand by it. When I have a migraine, drinking any type of fluid is the last thing I want to do, but adding a caffeine-withdrawal headache into the mix isn't worth it. Drink the coffee, or go off it all together.

Things that help with fibromyalgia and (autoimmune) arthritis:

PEA Supplements. I take 1200mg a day (spaced out morning/night), this can be ordered as 400mg tablets from Amazon pretty easily. It's for generalised chronic pain, but my dad literally has nerve damage and it made a difference for him, too, when he tried it. Makes a HUGE difference, even within a week of taking it.

Wrist and knee braces. Self explanatory, but they help with the joint pain.

Prescription Plaquenil 300mg for the fibro. Brought my fibro pressure points / markers down from the max (28 I think) to 21 in 6 months of taking it.

Things that help with chronic fatigue syndrome (CFS):

Things that help with POTS:

[trustedpharmacy]

Azithromycin is used to treat many different types of infections caused by bacteria such as respiratory infections, skin infections, ear, and eye infections. It works by stopping the growth of bacteria. If you want to buy azithromycin online then must visit trustedpharmacy.net.

[siglerprescriptiondrugcards]

Hydroxychloroquine Sulfate

Brand Name: Plaquenil

Generic Available

Common Dosage Forms:

Tablets: 200 mg (equivalent to 155 mg of base)

FDA Indications/Dosages:

Treatment of malaria due to Plasmodium vivax, P. malariae, P. ovale, and susceptible strains of P. falciparum:

Suppressive Treatment: 400 mg or 5 mg/kg body weight given once a week on the same day of the week. It is best to begin two weeks prior to exposure and continue for eight weeks after leaving area. If this is not possible, use a loading dose of twice the regular dose.

Acute attacks: 800 mg followed in 6 hours by 400 mg followed by 400 mg daily for two days.

Treatment of discoid and systemic lupus erythematosus: 200-400 mg once or twice daily.

Treatment of rheumatoid arthritis: 400-600 mg daily.

Monitor: Annual eye exam

Pharmacology/Pharmacokinetics: The exact mechanism of hydroxychloroquine in the treatment of malaria is unknown. It may raise the pH of certain components in sensitive parasites and interfere with lysosomal degradation of hemoglobin. It does not affect the exoerythrocytic tissues stages and therefore is not indicated for prophylaxis. It has a very large volume of distribution which adds to its long half-life of 3 days. Its mechanism in the treatment of discoid and systemic lupus erythematosus and rheumatoid arthritis is unknown.

Drug Interactions: No known clinically significant drug interactions exist.

Contraindications/Precautions: Contraindicated in patients hypersensitive or who have had visual disturbances attributable to 4-aminoquinolines. Do not use for long-term therapy in children. Children are particularly sensitive and small overdoses are toxic and sometimes fatal. Use caution in patients with psoriasis, porphyria, pregnancy, and hepatic disease. May cause retinopathy in long-term use. Any visual complaints should be taken seriously and appropriate tests should be conducted during long-term therapy. No Pregnancy Category Established.

Adverse Effects: Headache, dizziness, nausea, VISUAL DISTURBANCES, edema, weight loss, BLOOD DYSCRASIAS, nervousness, anorexia, and abnormal skin pigmentation.

Patient Consultation:

Take with food or milk to decrease GI upset.

Notify physician if any of the following occur: Flu-like symptoms, aches, soreness of the mouth, gums, or throat, sore joints, visual disturbances, or any unusual bleeding or bruising.

Store in a cool, dry place away from sunlight and children.

If a dose is missed, take it as soon as possible. If it is closer to the time of your next dose than the dose you missed, skip the missed dose and return to your normal dosing schedule. Do not double doses.

[pradeep-madgaonkar]

What is hydroxychloroquine?

Hydroxychloroquine is a prescription drug. It comes as an oral tablet. Hydroxychloroquine is sold under the brand name Plaquenil among others, is a medication used to prevent and treat malaria in areas where malaria remains sensitive to chloroquine. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. It is also being studied as a treatment for coronavirus disease 2019 (COVID-19)

Hydroxychloroquine may be used as part of a combination therapy. That means you may need to take it with other drugs.

[plaquenil41161-blog]

plaquenil tablets 2020

chloroquine without prescription coronavirus plaquenil Make an appointment with your doctor by phone and inform him about journeys you have made or about exposure to people who may have been places where the epidemic develops. What mistake does the Italians make? Grzesiowski always observes.

[hierdny]

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[zaras2424]

Hydroxychloroquine Market Growth, Drivers and Challenges Report

Global Hydroxychloroquine Market was estimated to be US$ 41.3 Mn in 2018 and is expected to reach US$ 100.4 Mn by 2030 growing at a CAGR of 10.4% over the forecast period. Rise in outbreak of global pandemic coronavirus or COVID-19 alerted governments and health authorities across various countries to develop preventive and curative medicines for this infectious disease. COVID-19 affect the immune system of lungs of infected persons. People with weak immune systems and having previous autoimmune disorders have a high probability of contacting the virus compared to other individuals. Presently government organizations, private organizations and healthcare service providers across the world is in research & development for a vaccine for COVID-19. Before a vaccine is commercially available, there is a growing for development of medicines that can suppress the effects of COVID-19 in human body. Presently a notable drug used in suppressing the effects of COVID-19 in human body is hydroxychloroquine (also known by the brand name ‘Plaquenil’). Generally hydroxychloroquine sulfate primarily used for autoimmune diseases including rheumatoid arthritis, lupus, malaria and other diseases. Hydroxychloroquine sulfate is a major drug used for curing malaria. The drug is currently available as a generic drug in the form of tablets majorly in the 200 mg formulation.

Access the Full Report @ https://www.absolutemarketsinsights.com/reports/Hydroxychloroquine-Market-2019-2027-546

The detailed research study provides qualitative and quantitative analysis of hydroxychloroquine market. The market has been analyzed from demand as well as supply side. The demand side analysis covers market revenue across regions and further across all the major countries. The supply side analysis covers the major market players and their regional and global presence and strategies. The geographical analysis done emphasizes on each of the major countries across North America, Europe, Asia Pacific, Middle East & Africa and Latin America.

Key Findings of the Report:

In terms of the application for hydroxychloroquine, coronavirus (COVID-19) is expected to be the major contributor of revenue to the market over the near future. The growth in cases across various countries is expected to drive the demand for the drug.

The distribution of hydroxychloroquine is observed to made more through the offline medium. The primary reasons for the same are the easier availability of the drug and the growing network of pharmacies and medical centers across the world.

As far as geography is concerned, North America accounted for the maximum share in the global hydroxychloroquine market in 2018. This can be attributed to the higher instances of autoimmune diseases amongst the population and growing manufacturer presence in the region.

Some of the players operating in the hydroxychloroquine market are Amneal Pharmaceuticals LLC., Dr. Reddy’s Laboratories, Inc, Ipca Laboratories Ltd., Laurus Labs Limited, Mylan N.V., NorthStar Rx LLC, Novartis AG, Prasco Laboratories, Sanofi, Teva Pharmaceutical Industries Ltd., and Zydus Cadila amongst others.

Hydroxychloroquine Market:

By Application

Rheumatoid Arthritis

Lupus Erythematosus

Malaria

Coronavirus (COVID-19)

Others

By Product Type

200 mg

300 mg

400 mg

Others

By Distribution Channel

Online

Offline

Retail Pharmacies

Hospitals/Clinics

Others

By Geography

North America

Europe

Asia Pacific

Middle East & Africa

Latin America

Contact Us: Company: Absolute Markets Insights Email id: sales@absolutemarketsinsights.com Phone: +91-740-024-2424 Contact Name: Shreyas Tanna Website: https://www.absolutemarketsinsights.com

[softrevolutionoflove]

Je kan de volgende 7 antioxidanten preventief innemen tegen COVID: ♥ Glutathion ♥ N-acetylcysteïne (= NAC) 750 mg ♥ Zink Deze 3 zijn de belangrijkste. Zink beschermt je gezonde lichaamscellen en draagt bij tot een normaal gezond immuunsysteem. NAC en Glutathion ontgiften heel je lichaam. NAC helpt je lichaam om glutathion aan te maken. Je kan gedurende 1 week Glutathion innemen, en de volgende week NAC 750. ♥ Quercetine (versterkt je opnamen van zink en ondersteunt je ademhalingsstelsel) ♥ Vitamine D3 (voor je immuunsysteem en gezonde celdelingsproces) ♥ Mariadistel (om je lever te ontgiften en om je maag te beschermen) ♥ Astaxantine 5 mg (voor je zicht en ontstekingen) ♥ Melatonine 1 à 10 mg. Je kan al deze antioxidanten 's morgens innemen, behalve de Melatonine die je 's avonds neemt +/- 30 minuten voor het slapen gaan. Don't be afraid, prevent getting ill with hydroxychloroquine (CDS). Take Plaquenil: hydroxychloroquine tablets to prevent getting COVID, day 1 you take 3 tablets of 200 mg a day. After the first week, keep taking 1 tablet a day and pray. In combination with 240 mg Zinc you shouldn't get COVID. If you are already ill with COVID, ask your doctor for the antibiotic Azithromycin. More than 100 people Recovered from Covid-19 with CDS by Physicians of the AEMEMI: https://lbry.tv/@Kalcker:7/100-Recovered-Aememi-1:7 Erectile problems and heart problems after COVID-19 injections! Erection problems are also known as: erectile dysfunction (ED) impotence sexual dysfunction. https://www.bitchute.com/video/WAYyYeUS5bIP/ Bioweapons, tons of research, testimonials of victims of COVID-19 injections. ‘An old drug against a new disease. We have a very good experience in Brazil. Against authorities in many cities and States - we are a Federation. The Health Ministry in Brazil has a protocol but the Highest Court and Governors do not approve and sometimes we do not have the medicine to buy. It is a war.’ How to make CDS the easy way: https://lbry.tv/@Kalcker:7/How_to_make_CDS:a?r=3HjkA7vfUjLE4gTappooSekm2PuYr5Du How to make CDS ? Easy way to prepare CDS with Andreas Kalcker from NaClO2 (sodium clorite) 25% and HCl (hidrocloric acid) 4% (caution do no confuse with hipoclorite, because hipoclorite is bleach) France: Raoul, USA: Zelenko NY. Meanwhile in Canada scientists found out that cannabis also works positively: https://nypost.com/2020/05/21/scientists-believe-cannabis-could-help-prevent-treat-coronavirus/ https://www.preprints.org/manuscript/202004.0315/v1 https://www.bnnvara.nl/zembla/artikelen/studie-waarop-who

7 antioxidants to prevent COVID and other kinds of influenza: ♥ Glutathion♥ N-acetylcystein (= NAC) 750 mg♥ Zinc♥ Quercetin♥ Vitamin D3♥ Artichoc♥ Astaxantin♥ Melatonin 1-10 mg to be taken at night +/- 30 min before you go to sleep.

[virologyconsultcovid19]

Chloroquine Use For COVID-19 Shows No Benefit In First Small—But Limited—Controlled Trial A pharmacist shows a box of tablets called "Plaquenil", on March 23, 2020, in Rennes, western Results from the first controlled study of hydroxychloroquine for treating COVID-19 showed no significant difference in outcomes between those who received the drug and those who received usual care. Hydroxychloroquine is one of [...] Click here to view original web page at www.forbes.com

[adrastiana]

I was eating radishes. This batch has an earthy/spicy taste. And I decided to take my plaquenil now because it’s supposed to be taken with food (and I seldom do that >> ). Bad idea. Something in the radishes must have made the tablet melt in my mouth. Plaquenil has quinine in it. Quinine is very very very very bitter. If you think tonic water tastes bad remember that stuff is meant to be tasted. Plaquenil needs to be swallowed fast before the bitterness makes you want to hurl. x.x

I tried killing the bitterness with an altoid. Now all I can taste is quinine’d altoids. x.x

[starindiamarket-blog]

gPlaquenil's launch and Indivior's guidance sends Dr. Reddy’s shares up 3%

gPlaquenil’s launch and Indivior’s guidance sends Dr. Reddy’s shares up 3%

Company has launched generic of Plaquenil in the US market, while Indivior’s guidance suggests that the gSuboxone generic is likely to be rolled out in CY18. Shares of Dr. Reddy’s Lab have surged 3% over favourable news flow today. Company announced that it has launched gPlaquenil (Hydroxychloroquine Sulfate Tablets USP, 200 mg) in the US market. Plaquenil is manufactured by Concordia…

[decisionforsight]

Global Hydroxychloroquine Market

Global Hydroxychloroquine Market Size, Share, Growth, Industry Trends and Forecast 2020-2030

The Global Hydroxychloroquine Market held USD 2 billion in 2020 and is to grow with a CAGR of 7.5% from 2020-2030. Hydroxychloroquine (HCQ) or Hydroxychloroquine sulfate, are widely sold under certain brands such as Quinoric, Axemal, Dolquine, Plaquenil, Hydroquin, Quensyl, and Quineprox. Hydroxychloroquine drugs were initially utilized for treatment of patients suffering from malaria. Hydroxychloroquine is being used owing to the pain and swelling reduction properties which is being used to cure rheumatoid arthritis. This drug also reduces joint damage and decrease probability of long-term disability. As per Clinical Research Data, 150 million people suffered from rheumatoid arthritis globally in 2017. Researchers are therefore indulged in testing the product usage for the treatment of coronavirus spread as it has shown positive results in case of some patients in China. Leading organizations such as U.S. FDA and EU has initially prescribed for use for treatment of patients suffering from arthritis as well as autoimmune diseases including lupus. However, rising cases of COVID-19 globally, has led to increased emphasis on the research and development of several others drugs related with its treatment. Recent studies and ongoing research and development shows increased signs of recovery phase of patients suffering from the coronavirus.

Download Sample Copy of the Report to understand the structure of the complete report (Including Full TOC, Table & Figures) @ https://www.decisionforesight.com/request-sample/DFS020392

Market Dynamics and Factors : 

Major driving factors for the market are increased government spending on the healthcare and medical sector, growing drugs production in Asian regions. Changing lifestyles of the population due to sudden spurt in cases of coronavirus in U.S., Brazil, India and China will create demand hydroxychloroquine market. India is leading producer and exporter of hydroxychloroquine drugs. Growing focus and trials to use hydroxychloroquine as game changing drug for treatment of Covid-19 will certainly drive the global hydroxychloroquine market. However, varying the prices of drug raw materials being supplied from China may restrain the growth of the market. Expanding use of HCQ in combination with others antibiotics such as azithromycin as potential cure of coronavirus disease will further act as an opportunity during the forecast period.

Market Segmentation:

Global Hydroxychloroquine Market – By Type of Disease

Lupus Erythematosus

Q Fever

Coronavirus Disease (COVID-19)

Rheumatoid Arthritis

Malaria

Porphyria Cutanea Tarda (PCT)

Others

Global Hydroxychloroquine Market – By Distribution Channel

Specialty Drug Store

Hospital Pharmacy

Retail Pharmacy

Online Pharmacies

Global Hydroxychloroquine Market – By Application

Tablets

Injectables

Global Hydroxychloroquine Market – By Geography

North America

U.S.

Canada

Mexico

Europe

U.K.

France

Germany

Italy

Rest of Europe

Asia-Pacific

Japan

China

India

Australia

Rest of Asia Pacific

ROW

Latin America

Middle East

Africa

New Business Strategies, Challenges & Policies are mentioned in Table of Content, Request TOC at @ https://www.decisionforesight.com/toc-request/DFS020392

Geographic Analysis : 

North America dominates the hydroxychloroquine market share with the large demand owing to growing use of HCQ IN U.S. The region is also a hub of advanced healthcare infrastructure and the growing expenditure of government on rapid development of make shift hospitals, development of novel disease controlling drugs is further fueling global hydroxychloroquine market growth. Asia Pacific hydroxychloroquine demand is also growing at a fast pace and expected to dominate in the future. Due to the growing demand for HCQ drugs, increasing drug production in India, is anticipated to drive hydroxychloroquine market size in coming years.

Competitive Scenario :

Global hydroxychloroquine market, is witnessing demand with certain players garnering major market share. In terms of market share, few of the major players currently dominate the market. Key companies are also expanding their manufacturing facilities to cater to growing demand for this drug globally. Key players enhancing the global hydroxychloroquine market size include Zydus Cadila, Bayer, Laurus Labs, Sun Pharma, Sanofi, Ipca Laboratories Ltd, Novartis AG, Teva Pharmaceutical Industries Ltd and McW Healthcare.

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The report offers statistical data in terms of value (US$) as well as Volume (units) till 2030.

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The data analysis present in the Global Hydroxychloroquine Market report is based on the combination of both primary and secondary resources.

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100+ charts exploring and analysing the Global Hydroxychloroquine Market from critical angles including retail forecasts, consumer demand, production and more

15+ profiles of top producing states, with highlights of market conditions and retail trends

Regulatory outlook, best practices, and future considerations for manufacturers and industry players seeking to meet consumer demand

Benchmark wholesale prices, market position, plus prices for raw materials involved in Global Hydroxychloroquine Market type

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[francisco90]

Hydroxychloroquine Uses, Working, Dosage, and Precautions

Hydroxychloroquine uses include the prevention and treatment of malaria and the treatment of rheumatoid arthritis and lupus. Sold under the name Plaquenil, hydroxychloroquine is also being studied for COVID-19 infection, which is caused by the novel coronavirus.

Hydroxychloroquine is a medication advised for the treatment or counteraction concerning malarial sickness. It is utilized as prophylaxis of jungle fever in regions where there are no reports of chloroquine obstruction. Aside from forestalling and treating intestinal sickness, the medication is broadly utilized by patients who have foundational lupus erythematosus and constant discoid lupus erythematosus. Likewise, hydroxychloroquine is shown for the treatment of rheumatoid joint inflammation in grown-ups. Accessible under the brand name Plaquenil, hydroxychloroquine got an endorsement from the U.S. Food and Drug Administration (FDA) in 1955.

Working

The specific activity system by which hydroxychloroquine forestalls or treats intestinal sickness is obscure. Be that as it may, hydroxychloroquine, similar to chloroquine, may follow up on the cell level by repressing certain chemicals and interfacing with DNA. It has been discovered that hydroxychloroquine has an intense antiviral impact on contaminations brought about by the strains of infections that cause respiratory malady. Its antiviral impacts are seen when the contaminated cells are treated with hydroxychloroquine, recommending it could be utilized to forestall or treat certain viral diseases.

Dosage And Directions

You should take hydroxychloroquine tablets orally, with food to forestall a gastric bombshell, precisely as exhorted by your PCP. Your primary care physician will inform the measurement and length with respect to treatment depending on your ailment. To forestall or treat jungle fever, you should take the medication precisely as suggested in light of the fact that the measurement design is distinctive for treating and forestalling intestinal sickness.

For rheumatoid joint inflammation or lupus, you should take hydroxychloroquine on more than one occasion every day, or as coordinated. Your PCP may encourage you to bit by bit increment your portion and may tighten your portion when your condition improves. If you are taking stomach settling agents, ensure you take this medication at any rate 4 hours prior or in the wake of taking them.

 Precautionary Measures And Warnings

Individuals hypersensitive to hydroxychloroquine uses ought not to utilize this medication. To ensure this antimalarial or hostile to rheumatic medication is alright for you, tell your PCP in the event that you have or have had any vision issues, coronary illness, arrhythmia, diabetes, stomach issues, liver or kidney sickness, interminable liquor addiction or a hereditary issue called G6PD lack.

Additionally, you should educate your PCP on the off chance that you are experiencing any treatment with OTC or doctor-prescribed medications, multivitamins, and so forth. It is muddled whether hydroxychloroquine uses will make any mischief a baby. On the off chance that you are pregnant or plan to get pregnant, advise your primary care physician. It is likewise hazy whether the medication goes into bosom milk, so check with your PCP about utilizing the medication during breastfeeding.

Try not to overdose with hydroxychloroquine tablets since it might make irreversible harm your eyes, prompting vision misfortune. You should take the medication for the full recommended length for jungle fever regardless of whether your side effects improve in a day or two. Hydroxychloroquine may make your skin more delicate to the sun, so keep away from sun introduction, tanning corners, and lights and utilize defensive dress when outside.

For More Enquiry,

Visit Website :    https://www.medexpressrx.com/hydroxychloroquine.aspx

[gizedcom]

Donald Trump has held back global efforts to find real treatments, SAGE scientists claims

Sir Jeremy Farrar said today the US President’s enthusiasm about hydroxychloroquine had held back global efforts to find Covid-19 treatments

Donald Trump’s endorsement of hydroxychloroquine as a coronavirus wonder drug has slowed down global efforts to beat the disease, a UK Government scientist suggested today.

Sir Jeremy Farrar implied the US President’s enthusiasm about the anti-malaria drug — which has since been proven not to have any effect on Covid-19 patients — ‘delayed and slowed down our progress in developing treatments’.

Trump first touted hydroxychloroquine in April, saying there were ‘very strong signs’ it could treat the viral disease based on limited anecdotal reports from US doctors and poor studies.

But last month, Oxford University’s Recovery trial, the biggest in the world, stopped enrolling participants to its hydroxychloroquine arm after concluding that it showed no clinical benefit.

President Trump has also admitted to taking the drug as a preventative therapy, to stop him from getting infected from the disease in the first place. Trials are currently ongoing to see if the tablets can work in this way.

Sir Jeremy, a member of Downing Street’s Scientific Advisory Group for Emergencies (Sage), said out of more than a thousand clinical trials of Covid-19 treatments around the world, 16 per cent are looking at hydroxychloroquine. 

He told a Chatham House briefing it ‘didn’t make any organised sense’ and blamed comments politicians for making statements about ‘certain drugs’ which proved not to be true and holding back progress of other potential therapies.

Trump first touted hydroxyhcloroquine in April, saying there were ‘very strong signs’ it could treat the viral disease based on very limited anecdotal reports from US doctors

The anti-malaria drug has since been proven not to have any effect on Covid-19 patients

Only one drug — the £5 steroid dexamethasone — has been conclusively proven to treat coronavirus. Ebola drug remdesivir has been approved to treat patients but the evidence is still mixed.

The Recovery trial found it reduced the risk of death by 35 per cent for patients relying on ventilators — the most dangerously ill — and by a fifth for all patients needing oxygen at any point.

Sir Jeremy said today: ‘I think there are 1,200 clinical trials currently in place around the world, of which 16 per cent are looking at chloroquine or hydroxychloroquine. That doesn’t make any organised sense.’

He suggested statements made by politicians in relation to drugs, which ended up not being true, had ‘delayed and slowed down our progress in developing treatments’. But he did not name any politicians in particular.

Sir Jeremy, who is also director of the Wellcome Trust, a research-charity based in London, claimed too many trials of potential treatments were too small to show definitive results.

He praised the Recovery trial — which has recruited 11,000 trialists — and the World Health Organization’s Solidarity trial, which has 5,000 volunteers.

But he added: ‘Many of the trials, and I think here the clinical community does need to take a harsh look at ourselves, many of the trials are too small. 

‘I think 40 pre cent will enrol less than 100 patients. It’s very unlikely in less than 100 patients you’re going to provide definitive evidence of the efficacy and safety of a treatment. 

VACCINE NATIONALISM ‘HAS NO PLACE’ IN THE COVID-19 FIGHT 

Sir Jeremy Farrar, who is a member of the Scientific Advisory Group for Emergencies (Sage), also warned against ‘nationalism’ when it comes to treatments and a vaccine.

He said the pandemic will affect all of us ‘until every country manages to steer a way through it’, adding: ‘So there’s no point being nationalistic, there’s no point saying “I’ve got my vaccine in America and nobody else will have it”, because that won’t work, and it won’t actually protect Americans.

‘Vaccine nationalism, therapeutic nationalism, has no place in enlightened self-interest, and they have to be seen as global public goods.’ 

His comments come after Donald Trump was earlier this month accused of ‘undermining’ the global Covid-19 fight by splashing the cash on one of only two drugs approved to treat the disease on the NHS. 

The US Department of Health and Human Services (HSS) revealed it had secured more than 500,000 treatment courses of remdesivir for American hospitals.

It represented the entire global supply for July and 90 per cent of stocks for August and September, leading to fears of an autumn shortage.   

‘You have to do things at scale as Recovery and Solidarity have done, and small trials will often be unhelpful, and will often be politicised as we have seen in this epidemic, where politicians sadly made statements about certain drugs which proved not to be true and I think delayed and slowed down our progress in developing treatments.’ 

Last month Oxford University scientists pulled the controversial drug from the Recovery trial after results showed it had no benefit on patients hospitalised with the virus.

A quarter of NHS patients given hydroxychloroquine died from Covid-19, compared to 23.5 per cent who were not prescribed the drug.

The scientists running the trial said the results were ‘pretty compelling’, adding: ‘This isn’t a treatment that works.’

Professor Martin Landray, lead author of the study, added: ‘If you’re admitted to hospital with Covid – you, your mother or anyone else — hydroxychloroquine is not the right treatment. It doesn’t work.’

He called for doctors around the world to stop using the drug, which can cause a slew of nasty side effects including heart arrhythmias, headaches and vomiting. 

But Professor Landray said the results do not necessarily mean the tablets cannot prevent people from catching Covid-19 in the first place, which several studies are still investigating. 

Early results on hydroxychloroquine from the RECOVERY trial were not supposed to released until July. 

But the study’s chief investigators said they felt compelled to release the data and set the record straight on the drug, which has been at the centre of furious debate. 

It comes after another study last week claimed that hydroxychloroquine can boost survival odds for some coronavirus patients.

Hospitalized coronavirus patients given hydroxychloroquine were 50 percent less likely to die of the brutal infection than those who did not receive the drug.

President Trump’s top economic adviser Peter Navarro claimed the US ‘could have saved 10s of thousands of lives’ if it used the drug from the start. 

But critics slammed the Henry Ford Health System retrospective analysis of 2,541 people, saying it wasn’t a randomised trial — the gold-standard type of scientific evidence.

Exerts warned more of the hydroxychloroquine group were given steroids, which data suggests combats dangerous inflammation in coronavirus patients.

WHY IS HYDROXY-CHLOROQUINE CONTROVERSIAL? 

Hydroxychloroquine – branded as Plaquenil – is a cheap drug that has been used to prevent malaria and treat lupus and rheumatoid arthritis for decades.

It was touted as a wonder drug by Donald Trump despite no evidence it could treat Covid-19. 

Hope was sparked early on in the crisis when a French study suggested the drug could have both antiviral and anti-inflammatory effects.

It triggered a flurry of research across the world, the endorsement from Trump and emergency authorization from US regulators.

The RECOVERY trial is the first randomised study to provide concrete evidence about the drug.

The results will likely have a knock-on effect around the globe, where tens of thousands of coronavirus patients are still being prescribed hydroxychloroquine. 

Leading doctors have also warned the drug can cause severe side effects, and can even throw off the process that makes the heart beat in time.

One trial in Brazil was stopped short because so many of the enrolled coronavirus patients given the drug developed these arrhythmias (abnormal heartbeats).

According to WebMD, side effects may include: 

Nausea, vomiting, loss of appetite, diarrhea, dizziness, or headache

Slow heartbeat, symptoms of heart failure (such as shortness of breath, swelling ankles/feet, unusual tiredness, unusual/sudden weight gain)

Mental/mood changes (such as anxiety, depression, rare thoughts of suicide, hallucinations)

Hearing changes (such as ringing in the ears, hearing loss), easy bruising/bleeding

Signs of infection or liver disease

Muscle weakness, unwanted/uncontrolled movements (including tongue/face twitching), hair loss, hair/skin color changes

Low blood sugar, severe dizziness, fainting, fast/irregular heartbeat, seizures.

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Inside story: Hydroxychloroquine

Hydroxychloroquine sulfate or Hydrochloroquine (HCQ) a.k.a Plaquenil is one of the anti-malarial medicine which knocked-out the recent news bulletin due to its correlation with Covid19. This medicine was originally designed to fight a certain type of Malaria.  Since 1955, this medicine has gained trust of a plethora of Americans. Consequently, HCQ made its position to World Health Organization (WHO) Model List of Essential Medicines.

Usage

How can HCQ become so popular if it can treat only Malaria? It is because, over the years pharmacologists discovered its effectiveness over other diseases like lupus erythematosus, rheumatoid arthritis, porphyria cutanea tarda and Q fever. Don’t worry if you can’t pronounce these pharmaceutical terms. Nevertheless, HCQ can send these diseases to the backseat.

Symptoms

Let’s check out the symptoms of these diseases:

Lupus Erythematosus: Chest pain during respiration, Joint pain, Oral ulcer, Fatigue, Weight-loss, Fever and Butterfly facial rash;

Rheumatoid Arthritis: Inflammation of joints, joints deformity, lung fibrosis and anaemia;

Porphyria Cutanea Tarda (PCT): Photosensitivity, blisters and hyperpigmentation;

Q Fever: Fever, malaise, headache, muscle pain, joint pain, nausea and loss of appetite;

Side effects

Excess of anything and everything is harmful. Inevitably, we have doctors to prescribe the right dosage of every medicine ever discovered. Here are few side effects of HCQ: retinopathy, abdominal cramps, heart problems, loss of hair and vomiting.

Can it cure Coronavirus?

Three out of five studies conducted at Qingdao, Marseille and Wuhan showed positive effects of HCQ on a limited number of Covid19 patients. Remaining two research studies in France and China showed no evidence of clinical benefit from the medicine. Based on the research and the news articles of various studies, it has been acclaimed that there is no clear-cut prevention cure of Covid19.

India is considered to be ‘The Pharmacy of the world’, manufacturing more than 70% of the world’s HCQ production.  Recently, Ministry of Health and Family Welfare (MoHFW) placed an order for 10 crore HCQ tablets with two pharmaceutical giants – IPCA laboratories and Zydia Cadia.

Even during lockdown, pharmacy companies are working around the clock to match the world’s requirement of HCQ. Since we do not have a full-fledged cure to prevent this global pandemic, we reside to the next best option – Hydroxychloroquine.

Pharmaceutical Chemistry is one of the major subject in all the Pharmacy colleges in India. Bangalore college of Pharmacy is one of the top pharmacy college in Bangalore which enhances pharmaceutical skills within students. This decade-old college is managed and operated by Bangalore Group of Institutions.