#ocuflox
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israa-abdelgani · 2 years ago
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قطرة اوكيوفلوكس – Ocuflox لعلاج التهابات العين البكتيرية قطرة اوكيوفلوكس – Ocuflox للقضاء على بعض مشاكل العين. تعرف على استخدامات هذا الدواء، جرعته المناسبة، الآثار الجانبية الناتجة عنه، سعره في الأسواق، بدائله
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Ofloxacin (Ophthalmic)
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Brand Name: Ocuflox
Generic Available
Dosage Forms:
Ophthalmic Solution: Each mL contains ofloxacin 3 mg and benzalkonium chloride 0.005% as a preservative.
FDA Indications/Dosages:
For the treatment of ophthalmic infections associated with corneal ulcers caused by susceptible strains of Pseudomonas aeruginosa, Serratia marcescens, or Staphylococcus aureus, Staphylococcus epidermidis: For the first two days, instill one to two drops in the affected eye every 30 minutes while awake and awaken at approximately four and six hours after retiring and instill one to two drops. From day three to seven, instill one to two drops hourly while awake. After day seven, instill one to two drops four times a day.
For the treatment of ophthalmic infections associated with conjunctivitis caused by susceptible strains of Haemophilus influenzae, Enterobacter cloacae, Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus epidermidis, or Streptococcus pneumoniae: One to two drops into the conjunctival sac(s) every two to four hours while awake for two days and one to two drops four times a day for the next five days.
Pharmacology/Pharmacokinetics: Ofloxacin is a fluoroquinolone antibiotic which exerts its bactericidal effect on susceptible bacteria by inhibiting DNA Gyrase, an enzyme essential to the duplication, transcription, and repair of bacterial DNA. Maximum serum concentrations are more than 1000 times less than those from an oral dose.
Drug Interactions: No known clinically significant drug interactions exist.
Contraindications/Precautions: Contraindicated in patients hypersensitive to ofloxacin or other quinolones. As with other antibacterial preparations, prolonged use of ofloxacin may result in overgrowth of non-susceptible organisms, including fungi. If superinfection occurs, appropriate therapy should be initiated. Discontinue at the first sign of a skin rash or any other sign of hypersensitivity reaction. Use with caution during pregnancy or in nursing mothers. Pregnancy Category C.
Adverse Effects: The most frequently reported drug-related adverse reactions are local burning or discomfort. Less frequent adverse reactions include foreign body sensation, itching, photophobia, blurred vision, dryness, and redness.
Patient Consultation:
Complete full course of therapy unless otherwise directed.
To instill drops: Lie down or tilt head backward and look up (holding dropper above eye), drop solution inside lower lid, and make sure dropper does not come in contact with eye or fingers. Then release lid, keeping the eye open for at least 30 seconds, and apply pressure to the inside corner of eye for at least one minute.
Wait at least 5 minutes before instilling other ophthalmic preparations.
Avoid tightly closing eyes after instillation.
Store in a cool, dry place away from sunlight and children.
Instill a missed dose as soon as possible.
Contact a physician if the above side effects are severe or persistent.
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sacred-life-connections · 6 years ago
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An Antibiotic That is Worrisome for Thyroid Patients by Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S.
When it comes to life-threatening infections, antibiotics have been a GodSend, however for minor infections the following antibiotics are troublesome and are known to cause some nasty side effects.
The antibiotic family I am referring to are fluoroquinolones. You may also see it referred to as quinolones. The following make up the quinolones: Ciprofloxacin, Cipro, Ciloxan eye drops, Levofloxacin, Levaquin, Quixin, Moxifloxacin, Avelox, Vigamox eye drops, Norfloxacin, Noroxin, Ofloxacin, Ocuflox, Floxin, Floxin Otic, Floxacin, Trovafloxacin, Trovan and alatrofloxacin.
Side effects include sudden severe insomnia, hypnic jerks, tendon and cartilage tears, brain fog, weird sensations like bugs crawling on you, headaches, buzzing, pain, tinnitus (ear ringing), face-down fatigue, moving abdominal pain and every thyroid symptom possible.
For people with thyroid disease, these antibiotics are especially worrisome because the quinolone antibiotics are built with a fluoride backbone. It is important to note that fluoride is extremely toxic to your thyroid.
Combining quinolone antibiotics with Levothyroxine (a T4 drug) may lead to reduced absorption of thyroid medicine and cause changes in TSH.
From a functional medicine perspective, fluoride competes with iodine which is necessary to make T4.
I don't like fluoride, or fluorine, or anything related to fluoride coming anywhere near your thyroid gland.
Four medications have been pulled off the market, and the remaining drugs have a "Black Box" warning on them from the FDA.
If you are taking an antibiotic check with your pharmacist to see if it is in the fluoroquinolone family.
If so you would be wise to ask your physician for another type of antibiotic. Again this plays an even more significant role if you are suffering with thyroid disease.
Reference:
Cohen, S. Thyroid Healthy. 2014
The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Grisanti and his functional medicine community. Dr. Grisanti encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional. Visit www.FunctionalMedicineUniversity.com for more information on our training in functional medicine. Look for practitioners who have successfully completed the Functional Medicine University's Certification Program (CFMP) www.functionalmedicinedoctors.com. This content may be copied in full, with copyright, contact, creation and information intact, without specific permission, when used only in a not-for-profit format. If any other use is desired, permission in writing from Dr. Grisanti is required.
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loyallogic · 5 years ago
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Landmark Infringement Cases for Infringement of Trademarks
This article is written by Sukriti Tiwari, pursuing a Diploma in Intellectual Property, Media and Entertainment Laws from Lawsikho.com. Here she discusses “Landmark Infringement Cases for Infringement of Trademarks”.
Section 29 of the Trademarks Act, 1999 defines infringement of trademarks as use of a mark which is ‘identical’ or ‘deceptively similar’ to a registered trademark by an unauthorized person. The Trademarks Act, 1999 allows both civil and criminal action to be taken against trademark infringement. As more and more cases of infringement come up before the courts in India, it is important to have a look at some landmark judgements related to the same.
1. The Maaza Fiasco – Whether one can register TM elsewhere post-sale
The Coca Cola Co. v. Bisleri International Pvt. Ltd. (Manu/DE/2698/2009)
Bisleri, which originally owned the trademark of mango drink MAAZA, sold it to Coca Cola in India. Bisleri later applied for registration of MAAZA trademark in Turkey and started to export the mango drink with the trademark of MAAZA. Coca Cola approached the Indian courts asking for an injunction along with damages against Bisleri for infringement of its trademark MAAZA as well as to restrain Bisleri from divulging the formulation of the drink. Coca Cola succeeded in obtaining a temporary injunction against Bisleri for infringement of the trademark.
2. Yahoo! – The case of identical names
Yahoo!, Inc. v. Akash Arora & Anr [78 (1999) DLT 285]
The domain names owned by the Plaintiff and the Defendant, ‘Yahoo!’ and ‘Yahoo India!’ respectively, were almost identical and similar phonetically too. It was felt by the plaintiff that this similarity would confuse and deceive users and lead them to believe that the two domain names were connected. It was held by the Delhi High Court that the name ‘Yahoo!’ has become distinct and unique and is associated with the plaintiff by public at large. It further held that even a domain name served a similar purpose as that of a trademark and must be granted similar protection.
3. Red Soled Shoes – whether louboutin’s prerogative
Christian Louboutin v. Pawan Kumar [CS (COMM) 714/2016]
The plaintiff found out the defendant had been selling women’s footwear with plaintiff’s ‘RED SOLE’ trademark. The ‘RED SOLE’ trademark has been registered in various countries by the plaintiff and it is a distinguishing characteristic of their products. The Delhi High Court held that the plaintiff is recognized by customers worldwide and the same is true for India. The ‘RED SOLE’ was held by the court to be a trademark that was well-known and people generally associated the ‘RED SOLE’ with Christian Louboutin. Damages by the defendant were also ordered to be paid.
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4. Activ or Active – Identical Sub-brands & Trade-dresses
M/S Castrol Limited & Anr. v. Iqbal Singh Chawla & Anr. [CS (OS) 4/2011]
The Plaintiff is the owner of the trademark ‘CASTROL’ and ‘ACTIV’. The Plaintiff found out in 2010 that the Defendant had been selling 4T oil under the ‘LUMAX ACTIVE’ trademark. The Plaintiff also alleged that the trade dress of its products, including the layout and the font, was being imitated by the Defendant. The Delhi High Court granted a permanent injunction against the Defendant for preventing the use of trademark ‘ACTIVE’ in a manner that resembled the packaging and font of the Plaintiff’s products. However, the Court clarified that the injunction would not restrain the Defendant from using their mark ‘ACTIVE’ in different packaging, font, and trade dress than that of the Plaintiff.
5. Fate of the first to enter market worldwide without domestic registration
Milmet Oftho Industries & Ors. v. Allergan Inc. [2004 (28) PTC 585 (SC)]
In this case, the Appellant, an Indian pharmaceutical company, was restrained by the Apex Court from adopting the trademark ‘OCUFLOX’. The Court held that even though the mark had neither been registered by the Respondent in India nor had it been used by the Respondent in the Indian market, it was to be protected because the Respondent was the first to enter the world market and to register the mark. This decision upheld the doctrine of trans-border reputation. The Court also emphasized that in the field of medicine, any and all probability of confusion and deception ought to be prevented in the interest of the public.
6. Gems or James – The Notorious Case of Phonetic Similarity
Cadbury India Limited and Ors. v. Neeraj Food Products [142 (2007) DLT 724]
The Plaintiff is a well-known producer and manufacturer of chocolates and confections and has a trademark ‘GEMS’ registered in its name. The Plaintiff approached the court for an injunction against the Defendant who was allegedly selling a product under the mark ‘JAMES BOND’ which resembled the ‘GEMS’ product of the Plaintiff in packaging and size. The Plaintiff claimed that the product sold with mark of ‘JAMES BOND’ was deceptively similar to ‘GEMS’. The court held that the products of the Defendant were indeed deceptively similar to that of the Plaintiff and granted an injunction restraining the Defendant from selling the said product.
7. KWIK Question – Whether Parts of Trademark Subject to Protection
Pidilite Industries Limited v. Poma-Ex Products & Ors. [2017 (72) PTC 1]
In this case, the Defendant was alleged to have dishonestly used mark ‘KWIK’, a part of Plaintiff’s trademark. The Defendant was using the trademark ‘KWIKHEAL’ and the packaging of the product was similar to Plaintiff’s ‘FEVIKWIK’ product. The High Court of Bombay held that the mark ‘KWIK’, being a dominant part of the trademark of the Plaintiff, cannot be adopted by the Defendant. The court further held that the phonetic similarity between the marks would easily mislead and deceive the consumers. ‘KWIK’ was held to be a dominant part of the Plaintiff’s trademark and an injunction was granted restricting the Defendant from using the same.
8. TOY-ing with Personality Rights & TMs – The Case of Daler Mehndi Dolls
DM Entertainment v. Baby Gift House and Ors. (MANU/DE/2043/2010)
Pop-star Daler Mehndi had assigned the trademark ‘DALER MEHNDI’ along with personality rights to the Plaintiff company. The Defendant started to Daler Mehndi dolls and cashed in on the artist’s popularity. The Plaintiff approached the court for grant of permanent injunction against the Defendant. The court duly recognized the artist’s publicity rights as well as the celebrity merchandising rights that belonged to the Plaintiff and issued an injunction against the Defendant.
9. H&M – Honest Mistake or Not; Almost Identical Marks
H&M Hennes & Mauritz AB Anr. v. HM Megabrands Pvt. Ltd. & Ors. (IA-7259/2016)
The Plaintiff, a well-known fashion brand with thousands of outlets worldwide, had adopted the ‘H&M’ trademark in 1970 and it was registered in India in 2005. The Plaintiff alleged the Defendant had infringed their trademark by representing their ‘HM’ mark using the same colour combination of red and white as used by the Plaintiff. The Defendant contended that their usage and adoption of the mark was innocent and that the mark stood for the names of their directors. The Defendant further argued that since the Plaintiff entered the Indian market much later, their mark had not acquired any reputation in India when the Defendant adopted their ‘HM’ mark in 2011. The Court ruled in favour of the Plaintiff and held that in case of a brand having trans-border reputation it is not necessary for it to set up shop in India for its trademark to be protected in India. Hence, the Defendant was restrained from using the ‘HM’ mark or any other deceptive variations of the same.
10. What’s in a Cuppa? – Clever Emulation Yet Deceptively Similar Logo
Starbucks Corporation v. Sardarbuksh Coffee & Co. & Ors. [CS (COMM) 1007/2018]
The Plaintiff is a well-known chain of coffee outlets spread over the world including India. The Plaintiff registered its trademark ‘STARBUCKS’ and logo representing a “long-haired crowned maiden” in India in 2011. The Defendants started their venture in 2015 using a logo with a black circular band saying ‘SARDARBUKSH COFFEE & CO.’ and the image of a turbaned man and wavy lines behind him. This logo used the colour scheme of the logo of the Plaintiff. The Delhi High Court held that the trade-name as well as the logo of the Defendants was deceptively similar to that of the Plaintiff and granted relief to the Plaintiff and ordered the Defendants to adopt the name ‘SARDARJI-BAKHSH COFFEE & CO.’ for running their business.
11. The Three Stripe Struggle – Adidas Irked by Forever 21 Using Stripes Similar to its TM
Adidas America, Inc. v. Forever 21, Inc. [3:17-cv-00377]
Adidas is a well-known MNC involved in making shoes, apparel, and other fashion accessories. While, Forever 21 deals in fast-fashion. It was in 2015 that Adidas first claimed Forever 21 to be misusing Adidas’s trademark “Three Stripes Mark” design by offering for sale various products resembling Adidas’s products and even selling “repurposed Adidas” products that were actually counterfeits. Adidas contended that it does not merely use the triple stripes as a design element, rather it proves as a brand identifier for consumers to recognize the band. Adidas also pointed out the massive investments, which run into millions of dollars, it has made to cultivate the “Three Stripe Mark”. It further stated that it has been using the said mark since 1952. The parties, however, did opt for an out-of-court settlement in 2016. But it was in March 2017 that Adidas chose to sue Forever 21 again, along with its suppliers, for wrongfully using the “Three Stripe Mark” and infringing its long-standing trademark. Forever 21 has actively defended its stance and has adamantly chosen to defy Adidas’s claim. Forever 21 contends that Adidas does not have a right to allege that each and every item having stripes causes an infringement of its trademark. It further claims that at least some elbow room be given for the use of stripes on products for decorative and design purposes. The matter is sub judice, though Forever 21 filed for a stay as it was undergoing bankruptcy proceedings.
Conclusion
With each case, the scope of trademark infringement is being widened and further clarified by the Indian courts. As more and more businesses go global, it is imperative that trademark jurisprudence keeps evolving. The domestic scenario in India is also brimming with start-ups, leading numerous big businesses to exercise their trademark rights against deceptively similar products and brands. New issues involving international businesses are coming up every day and the need of the hour is an international legal framework that is capable of being enforced universally to prevent and cure trademark infringements world over.
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awesomearabmedicalpro · 5 years ago
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Ofloxacin (Ocuflox) مقابل Tobramycin (Tobrex): المضادات الحيوية لالتهابات العين
ما هي الآثار الجانبية للوفلوكساسين والتوبراميسين؟
أوفلوكساسين
الآثار الجانبية الأكثر شيوعا من ofloxacin الجهازية ما يلي:
وقد وصفت الحساسية ، مثل خلايا النحل والحساسية المفرطة (صدمة).
تشمل الآثار الجانبية المهمة الأخرى أعراض تحفيز الجهاز العصبي ، مثل:
قد يسبب أوفلوكساسين مستويات منخفضة أو عالية من السكر في الدم خاصة في مرضى السكري الذين يتناولون الأنسولين أو أدوية سكر الدم عن طريق الفم.
يمكن للمرضى الذين يتناولون عقار أوكسلين تطوير حساسية الجلد (حساسية ضوئية) لتوجيه ضوء الشمس ويجب تجنب التعرض لأشعة الشمس أو استخدام واقي من الشمس واقيات الشمس.
وقد ارتبط الأوكسيلسين والمضادات الحيوية الأخرى في فئة الفلوروكينولون من المضادات الحيوية بالتهاب الأوتار وحتى تمزق الأوتار ، وخاصة في وتر العرقوب. يوصي بعض الأطباء بأن يتوقف المرضى عن ممارسة التمرينات الرياضية القوية أثناء تناولهم المضادات الحيوية الفلورية.
يجب استخدام Ofloxacin بحذر في المرضى الذين يعانون من أمراض الجهاز العصبي المركزي مثل النوبات بسبب نوبات نادرة تم الإبلاغ عنها في المرضى الذين يتلقون هذا الدواء.
يجب تجنب استخدام عقار الأوكسيلسين في الأطفال والمراهقين دون سن 18 عامًا ، حيث لم يتم إثبات الاستخدام الآمن لهؤلاء المرضى.
العديد من المضادات الحيوية ، بما في ذلك الأوكسجين ، يمكن أن تغير البكتيريا الطبيعية في القولون وتشجع النمو الزائد للبكتيريا المسؤولة عن تطور التهاب القولون (كلوستريديوم صعب ، التهاب القولون الغشائي الكاذب). يمكن أن يسبب التهاب القولون الغشائي الكاذب الحمى وآلام البطن والإسهال وحتى الصدمة في بعض الأحيان.
لا ينبغي أن يستخدم Ofloxacin في المرضى الذين يعانون من الوهن العضلي الوبيل لأنه يمكن أن يزيد من ضعف العضلات.
التوبراميسين
الآثار الجانبية المرتبطة باستخدام قطرات عين التوبراميسين تقتصر في الغالب على منطقة (مناطق) التطبيق. الآثار الجانبية المبلغ عنها تشمل:
تمزق،
تورم العين ، و
الحكة ، لاذع ، أو حرق العين.
إدارة قطرات العين قد تسبب مشاكل مؤقتة في الرؤية بما في ذلك عدم وضوح الرؤية. يجب ألا يشارك المرضى في أنشطة خطرة مثل القيادة حتى تتحسن رؤيتهم.
على الرغم من أن ردود الفعل التحسسية الخطيرة تجاه التوبراميسين ��ير محتملة ، إلا أن المريض المشتبه بتعرضه لمثل هذا التفاعل يجب أن يطلب المساعدة الطبية الطارئة. أعراض الحساسية الخطيرة قد تشمل:
صعوبة في التنفس ،
تورم اللسان ،
الوجه ، أو الحلق ، و
طفح شديد.
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israa-abdelgani · 2 years ago
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قطرة اوكيوفلوكس – Ocuflox لعلاج التهابات العين البكتيرية
قطرة اوكيوفلوكس – Ocuflox للقضاء على بعض مشاكل العين. تعرف على استخدامات هذا الدواء، جرعته المناسبة، الآثار الجانبية الناتجة عنه، سعره في الأسواق، بدائله
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Pharmacology - Chapter 4 - Antibiotics and Antifungals - Part Three
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Part One
Part Two
Part Four
Part Five
Transcription under the cut!
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Fighting Bacterial Infections
Major Classes of Antibiotic Drugs: Metronidazole
Therapeutic uses: Amebic dysentery, bacterial vaginosis, Clostridium difficile, Giardia infection, Helicobacter pylori ulcers, intestinal infections, rosacea, Trichomonas
Side effects: headache, anorexia, vomiting, diarrhea, abdominal cramps, metallic taste, urine discoloration
Dispensing issues: taking with food may reduce GI effects, potential for confusion between the topical and vaginal forms
Examples of agents: Metronidazole (Flagyl)
Major Classes of Antibiotic Drugs: Linezolid
How it works: Inhibits bacterial protein synthesis
Therapeutic uses: MRSA, VRE, other Gram positive infections
Side effects: headache, diarrhea, decreased hemoglobin, leukopenia, thrombocytopenia
Dispensing issues: protect from light
Examples of agents: Linezolid (Zyvox)
Major Classes of Antibiotic Drugs: Daptomycin
How it works: Inhibition of DNA and RNA synthesis
Therapeutic uses: Complicated skin and skin structure infections, Staphylococcus aureus blood infections
Side effects: anemia, diarrhea, vomiting, constipation, chest pain, peripheral edema, skin rash, respiratory side effects
Dispensing issues: dextrose-containing solutions not to be used, only NS or lactated Ringer's solution
Examples of agents: Daptomycin (Cubicin)
Storage of Liquid Antibiotics
Storage Requirements
Some antibiotics require refrigeration
Some antibiotics may be stored at room temperature
Appropriate for technicians to discuss this information with patient
Medication flavors
Technician may suggest and change flavors
Increases adherence in children
Ophthalmic Antibiotics
Manufacturing requirements
pH
Sterility
Dispensing issues
Expensive
Often rejected by insurance companies
Inform prescriber regarding medications insurance will most likely cover
Ophthalmic Products
Azithromycin (AzaSite)
Bacitracin (AK-Tracin)
Ciprofloxacin (Ciloxan)
Erythromycin (Ilotycin)
Gatifloxacin (Zymar)
Gentamicin (Gentak, Genoptic)
Moxifloxacin (Vigamox)
Ofloxacin (Ocuflox)
Sodium sulfacetamide (Bleph-10)
Tobramycin (Tobrex)
Sexually-Transmitted Infections
Definition
Genital system infections transmitted by sexual activity
Formerly known as venereal diseases
Prevention
Abstinence
Long-term monogamous relationship with an uninfected partner
Chlamydia
Caused by Chlamydia trachomatis
Often asymptomatic
Occurs frequently with gonorrhea
Potential for reinfection if partner not treated
Gonorrhea
Caused by Neisseria gonorrhoeae
Males: painful urination and discharge of pus
Females: abdominal pain due to PID
Long-term complications include sterility
Untreated infections may lead to systemic infections involving the heart, meninges, eyes, pharynx, joints
Occurs frequently with chlamydia
Syphilis: caused by Treponema pallidum
Primary-stage infection
Chancre at site of infection which heals in weeks
Fluids from chancre highly infectious
Bacteria enter bloodstream and lymphatic system
Secondary-stage infection
Skin rash, patchy hair loss, malaise, mild fever
Lesions highly infectious
Symptoms subside, disease becomes latent
Late- or tertiary-stage infection
Occurs after at least 10 years
Rubbery tissue masses in organs and on skin
Deafness, blindness, CNS lesions, perforation of the roof of the mouth may occur
Congenital syphilis
Pregnancy in tertiary-stage: neurologic damage to fetus
Pregnancy in primary- or secondary-stage: stillbirth
Nongonococcal urethritis
Caused by catheters, chemical agents, or sexual transmission
Male symptoms: mild
Female symptoms: serious
Vaginitis
Characterized by vaginal discharge and odor
Gardnerella vaginitis
Caused by interaction between the organism and anaerobic bacteria in the vagina
Frothy discharge, fishy odor, vaginal pH of 5 to 6
Trichomonas vaginalis
Bacteria found in males and females
Potential for infection if vaginal acidity is disturbed
Profuse, yellowish, or light cream-colored discharge with disagreeable odor
Irritation and itching
Agents for Treating Sexually-Transmitted Infections
Azithromycin (Zithromax)
Syphilis lesions (chancroid) in men
Chlamydia in women
Gonoccoccal in either sex
Ceftriaxone (Rocephin)
Penicillinase-producing bacteria
Tetracycline (Sumycin), Erythromycin (Ilotycin)
Chlamydia trachomatis
Penicillin G benzathine (Bicillin L-A)
Syphilis
Doxycycline (Doryx, Vibramycin)
Lymphogranuloma venereum
Metronidazole (Flagyl)
Gardnerella vaginitis
Safety Alert
Bicillin L-A and Bicillin C-R (which is combined with penicillin G procaine) are frequently dispensed in place of each other. However, the procaine in the Bicillin C-R makes it shorter acting. The longer-acting Bicillin L-A is needed for syphilis.
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awesomearabmedicalpro · 5 years ago
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Ofloxacin (Ocuflox) مقابل Tobramycin (Tobrex): المضادات الحيوية لالتهابات العينhttps://t.co/zxpWhr59lc
http://twitter.com/ArabmedicalP/status/1194191541956333569
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awesomearabmedicalpro · 5 years ago
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Ofloxacin (Ocuflox) مقابل Levofloxacin (Levaquin): مقارنة المضادات الحيوية
ما هي الآثار الجانبية للوفلوكساسين مقابل ليفوفلوكساسين؟
أوفلوكساسين
الآثار الجانبية الأكثر شيوعا للأوفلوكساسين تشمل:
وقد وصفت الحساسية ، مثل خلايا النحل والحساسية المفرطة (صدمة).
تشمل الآثار الجانبية المهمة الأخرى أعراض تحفيز الجهاز العصبي ، مثل:
قد يسبب أوفلوكساسين مستويات منخفضة أو عالية من السكر في الدم خاصة في مرضى السكري الذين يتناولون الأنسولين أو أدوية سكر الدم عن طريق الفم.
يمكن للمرضى الذين يتناولون عقار أوكسلين تطوير حساسية الجلد (حساسية ضوئية) لتوجيه ضوء الشمس ويجب تجنب التعرض لأشعة الشمس أو استخدام واقي من الشمس واقيات الشمس.
وقد ارتبط الأوفلوكساسين وكذلك المضادات الحيوية الأخرى في فئة الفلوروكينولون من المضادات الحيوية بالتهاب الأوتار وحتى تمزق الأوتار ، وخاصة في وتر العرقوب. يوصي بعض الأطباء بأن يتوقف المرضى عن ممارسة التمرينات الرياضية القوية أثناء تناولهم المضادات الحيوية الفلورية.
يجب استخدام Ofloxacin بحذر في المرضى الذين يعانون من أمراض الجهاز العصبي المركزي مثل النوبات بسبب نوبات نادرة تم الإبلاغ عنها في المرضى الذين يتلقون هذا الدواء.
يجب تجنب استخدام عقار الأوكسيلسين في الأطفال والمراهقين دون سن 18 عامًا ، حيث لم يتم إثبات الاستخدام الآمن لهؤلاء المرضى.
يمكن للعديد من المضادات الحيوية ، بما في ذلك الأوكسجين ، تغيير البكتيريا الطبيعية في القولون وتشجيع النمو الزائد للبكتيريا المسؤولة عن تطور التهاب القولون (كلوستريديوم صعب ، التهاب القولون الغشائي الكاذب). يمكن أن يسبب التهاب القولون الغشائي الكاذب الحمى وآلام البطن والإسهال وحتى الصدمة في بعض الأحيان.
لا ينبغي أن يستخدم Ofloxacin في المرضى الذين يعانون من الوهن العضلي الوبيل لأنه يمكن أن يزيد من ضعف العضلات.
الليفوفلوكساسين
الآثار الجانبية الخطيرة والتحذيرات تشمل:
ارتبط الليفوفلوكساسين بالإضافة إلى المضادات الحيوية الأخرى في فئة الفلوروكينولون من المضادات الحيوية بالتهاب الأوتار وحتى تمزق الأوتار ، وخاصة في وتر العرقوب.
الفلوروكينولونات لها نشاط إعاقة عصبي عضلي ويمكن أن تزيد من ضعف العضلات لدى الأفراد الذين يعانون من الوهن العضلي الوبيل.
الآثار الجانبية الأكثر شيوعًا هي:
تشمل الآثار الجانبية الأقل شيوعًا ما يلي:
وصفت الحساسية النادرة:
تشمل الآثار الجانبية الخطيرة المحتملة للليفوفلوكساسين:
الآثار الجانبية الخطيرة الأخرى والأحداث السلبية لليفوفلوكساسين تشمل:
يجب استخدام الليفوفلوكساسين بحذر في المرضى الذين يعانون من أمراض الجهاز العصبي المركزي مثل النوبات ، لأنه تم الإبلاغ عن نوبات نادرة لدى المرضى الذين يتلقون ليفاكوين.
يجب تجنب الليفوفلوكساسين عند الأطفال والمراهقين الذين تقل أعمارهم عن 18 عامًا ، نظرًا لعدم تحديد الاستخدام الآمن لهؤلاء المرضى.
العديد من المضادات الحيوية ، بما في ذلك الليفوفلوكساسين ، يمكن أن تغير البكتيريا الطبيعية في القولون وتشجع النمو الزائد للبكتيريا المسؤولة عن تطور التهاب القولون ، (C. التهاب القولون الصعب أو الغشائي الكاذب). يجب على المرضى الذين يعانون من علامات التهاب القولون الغشائي الكاذب بعد بدء Levaquin (الإسهال والحمى وآلام البطن ، وربما صدمة) الاتصال بطبيبك على الفور.
يمكن للمرضى الذين يتناولون ليفوفلوكساسين تطوير حساسية الجلد لتوجيه أشعة الشمس (حساسية للضوء) ويجب تجنب التعرض لأشعة الشمس أو استخدام حاجب الشمس.
يؤ��ي الفلوروكينولونات إلى تدهور مستويات السكر في الدم عند اقترانه بالسلفونيل يوريا (على سبيل المثال ، الغليبيريد) [Micronase, Diabeta, Glynase, Prestab]).
بسبب الآثار الجانبية الخطيرة المرتبطة بالفلوروكينولونات ، لا ينبغي استخدامها لعلاج التهابات المسالك البولية غير المعقدة ، وتفاقم البكتيريا الحاد لالتهاب الشعب الهوائية المزمن أو التهاب الجيوب الأنفية البكتيري الحاد ما لم تكن هناك بدائل أخرى.
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awesomearabmedicalpro · 5 years ago
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Ofloxacin (Ocuflox) مقابل Levofloxacin (Levaquin): مقارنة المضادات الحيويةhttps://t.co/bgjHxS5oo9
http://twitter.com/ArabmedicalP/status/1187640158759211008
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