#mucopolysaccharides

[biology-geology-beaches-india]

TSRNOSS, page 172.

[stimulated-radiation-emission]

oh god im on the genetics/biochem side of wikipedia. might as well get a bath started now for my upcoming reading hours

[i-talk-about-plants-to-strangers]

Aloe is a genus for over 600 varieties of flowering succulents. Aloe vera is probably the best known of these, typically for its high content of acemannan, a mucopolysaccharide with just. A ton of things it can do.

Fun fact, I am actually allergic to Aloe vera products (my skin gets very painful when it's applied) but I didn't realize this for god knows how long because I only ever used it for sunburns.

But typically, its used in lotions, for bites, minor burns, skin abrasions, and windburn.

Aloe skin contains aloin, sometimes known as barbaloin, which is toxic and is apparently used as a stimulant laxative and when dried it's occasionally used as a bittering agent for alcohol. A notable thing here is that a lot of varieties of aloe can be used to make these 'purgative medications' if you will. Because aloin. Yeah.

Sorry I didn't mean to spend the aloe post talking about laxatives but that is a good 60% of the information I'm finding.

TIME TO GET SCIENTIFIC I THINK

Returning to acemannan, it's currently in use for treatment of fibrosarcoma in pets (a type of tumor thing in muscle tissue). In fact, acemannan apparently induce macrophages to secrete tumor necrosis factor-α (TNF-α), interferon (IFN), and interleukins (IL-1). Essentially it seems to have antiviral potential and even could prevent things like HIV. (I need to double check sources on this, but from what I've seen so far it seems accurate which is cool as hell. Essentially the in vitro studies (test on microbes) it worked but in vivo (test on larger things) didn't.)

[dr-smita-goel-homeopathy-clinic]

*Dr. Smita Goel Homeopathy Clinic*

www.thehomeopathyclinic.co.in

A person with short stature, or restricted growth, does not grow as tall as other people of the same gender, age, and ethnicity. The person's height is below the 3rd percentile.

Short stature can be a variant of normal growth, or it may indicate a disorder or condition.

Growth rate is an important indicator of overall health. Children who do not reach the 5th percentile by the age of 5 years are said to be small for gestational age (SGA). A pediatrician will look out for signs of "failure to thrive."

Early intervention can prevent future problems in many cases.

Normally, at 8 years of age, a child's arm span is around the same as their height. If these measurements are out of proportion, this may be a sign of disproportionate short stature (DSS), sometimes known as "dwarfism."

Fast facts on short stature

Here are some key points about short stature. More detail is in the main article.

• Short stature can happen for a wide range of reasons, including having small parents, malnutrition, and genetic conditions such as achondroplasia.

• Proportionate short stature (PSS) is when the person is small, but all the parts are in the usual proportions. In disproportionate short stature (DSS), the limbs may be small compared with the trunk.

• If short stature results from a growth hormone (GH) deficiency, GH treatment can often boost growth.

• Some people may experience long-term medical complications, but intelligence is not usually affected.

Causes

Growth depends on a complex range of factors, including genetic makeup, nutrition, and hormonal influences.

The most common cause of short stature is having parents whose height is below average, but around 5 percent of children with short stature have a medical condition.

Conditions that can underlie short stature include:

• Undernutrition, due to a disease or lack of nutrients

• Hypothyroidism, leading to a lack of growth hormone

• A tumor in the pituitary gland

• Diseases of the lungs, heart, kidneys, liver, or gastrointestinal tract

• Conditions that affect the production of collagen and other proteins

• Some chronic diseases, such as celiac disease and other inflammatory disorders

• Mitochondrial disease, which can affect the body in different ways, including growth

Sometimes, an injury to the head during childhood can lead to reduced growth.

A lack of growth hormone can also lead to delayed or absent sexual development.

Rheumatologic diseases, such as arthritis, are linked to short stature. This may happen because of the disease, or as a result of the glucocorticoid treatment, which can affect the release of growth hormone.

Disproportionate short stature (DSS) usually stems from a genetic mutation that affects the development of bone and cartilage and undermines physical growth.

The parents may not have short stature, but they may pass on a condition that is linked to DSS, such as achondroplasia, mucopolysaccharide disease, and spondyloepiphyseal dysplasia (SED).

Types

There are different types and causes of short stature, or restricted growth, and they will present differently. Because the range of conditions is so broad, restricted growth can be classified in various ways.

One categorization is:

• Variant restricted growth

• Proportionate short stature (PSS)

• Disproportionate short stature (DSS)

Each of these categories includes a number of types and causes of short stature.

Variant restricted growth

Sometimes a person is small but otherwise healthy. This can be referred to as variant restricted growth. It may happen for genetic or hormonal reasons.

If the parents are also small, this can be called familial short stature (FSS). If it stems from a hormonal issue, it is a constitutional delay in growth and adolescence (CDGA).

The limbs and the head develop in proportion with the spine, and the individual is otherwise healthy.

Growth happens throughout the body, so the legs, for example, are in proportion with the spine.

In most cases, the individual's parents are also small, but sometimes small stature happens because the body does not produce enough growth hormone (GH), or the body does not process growth hormone properly. This is known as GH insensitivity. Hypothyrodism can lead to low hormone production.

Growth hormone treatment during childhood may help.

Proportionate short stature (PSS)

Sometimes, overall growth is restricted, but the person's body is in proportion, and the individual has a related health problem. This is known as proportionate short stature (PSS).

If the individual is heavy for their height, this can suggest a hormone problem. The problem could be hypothyroidism, excess glucorticoid production, or too little GH.

A person who is small and their weight is low for their height may be experiencing malnutrition, or they may have a disorder that leads to malabsorption.

Whatever the underlying reason, if it affects overall growth, it may impact development in at least one body system, so treatment is needed.

During adulthood, a person with this type of restricted growth is more likely to experience:

• osteoporosis

• cardiovascular problems

• reduced muscle strength

Rarely, there may be cognitive problems, or problems with thinking. This depends on the cause of the short stature.

Disproportionate short stature (DSS)

Disproportionate short stature (DSS) is linked to a genetic mutation. The parents are usually of average height. As with other types of short stature, a range underlying causes is possible.

An individual with DSS will be small in height, and they will have other unusual physical features. These may be visible at birth, or they may develop in time as the infant develops.

Most individuals will have an average-sized trunk and short limbs, but some people may have a very short trunk and shortened, but disproportionately large limbs. Head size may be disproportionately large.

Intelligence or cognitive abilities are unlikely to be affected unless the person has hydrocephalus, or too much fluid around the brain.

Achondroplasia underlies around 70 percent of cases of DSS. It affects around 1 in 15,000 to 1 in 40,000 people.

Features include:

• an average-sized trunk

• short limbs, especially the upper arms and legs

• short fingers, possibly with a wide space between the middle and ring fingers

• limited mobility in the elbows

• a large head with a prominent forehead and flattened bridge of the nose

• bowed legs

• lordosis, a progressive development of a swayed lower back

• average adult height of 4 feet, or 122 cm

Hypochondroplasia is a mild form of achondroplasia. It may be difficult to differentiate between familial short stature and achondroplasia.

Achondroplasia and hypochondroplasia result from a genetic mutation.

Genetic conditions, such as Turner syndrome, Down syndrome, or Prader Willi syndrome, are also linked to DSS.

Diagnosis

Some types of short stature can be diagnosed at birth. In other cases, routine visits to a pediatrician should reveal any abnormal growth pattern.

The doctor will record the child's head circumference, height, and weight.

If the doctor suspects restricted growth, they will carry out a physical examination, look at the child's medical and family history, and possibly carry out some tests.

These may include:

An x-ray, to assess for problems with bone development

An insulin tolerance test, to check for a deficiency in the growth hormone insulin-like growth factor-1 (IGF-1).

In this test, insulin is injected into a vein, causing blood glucose levels to drop. Normally, this would trigger the pituitary gland to release growth hormone (GH). If GH levels are lower than normal, there may be a GH deficiency.

Other tests include:

• a thyroid-stimulating hormone test, to check for hypothyroidism

• a complete blood count, to test for anemia

• metabolic tests, to assess liver and kidney function

• erythrocyte sedimentation and C-reactive protein tests, to assess for inflammatory bowel disease

• urine tests can check for enzyme deficiency disorders

• tissue transglutinase and immunoglobulin A tests, for celiac disease

• imaging scans, such as an x-ray of the skeleton and the skull or an MRI, can detect problems with the pituitary gland or hypothalamus

• bone marrow or skin biopsies may help confirm conditions associated with short stature

Treatment

Treatment will depend on the cause of the short stature.

If there are signs of malnutrition, the child may need nutritional supplements or treatment for a bowel disorder or other condition that is preventing them from absorbing nutrients.

If growth is restricted or delayed because of a hormonal problem, GH treatment may be necessary.

Pediatric hormone treatment: In children who produce too little GH, a daily injection of hormone treatment may stimulate physical growth later in life. Medications, such as somatropin, may eventually add 4 inches, or 10 centimeters, to adult height.

Adult hormone treatment

: Treatment for adults can help protect against complications, for example, cardiovascular disease and low bone mineral density.

Somatropin, also known as recombinant GH, might be recommended for people who:

• have a severe growth hormone deficiency

• experience impaired quality of life

• are already receiving treatment for another pituitary hormone deficiency

Adult patients generally self-administer daily with an injection.

Adverse effects of somatropin include headache, muscle pain, edema, or fluid retention, problems with eyesight, joint pain, vomiting, and nausea.

The patient may receive treatment to control chronic conditions, such as heart disease, lung disease, and arthritis.

Treatment for DSS

As DSS often stems from a genetic disorder, treatment focuses mainly on the complications.

Some patients with very short legs may undergo leg lengthening. The leg bone is broken and then fixed into a special frame. The frame is adjusted daily to lengthen the bone.

This does not always work, it takes a long time, and there is a risk of complications, including:

• pain

• the bone forming badly or at an inappropriate rate

• infection

• deep vein thrombosis (DVT), a blood clot in a vein

Other possible surgical treatments include:

• use of growth plates, where metal staples are inserted into the ends of long bones where growth takes place, to help bones grow in the right direction

• inserting staples or rods to help the spine form the right shape

• increasing the size of the opening in the bones of the spine to reduce pressure on the spinal cord

Regular monitoring can reduce the risk of complications.

Complications

A person with DSS may experience a number of complications.

These include:

• arthritis later in life

• delayed mobility development

• dental problems

• bowed legs

• hearing problems and otitis media

• hydrocephalus, or too much fluid in the brain cavities

• hunching of the back

• limb problems

• swaying of the back

• narrowing of the channel in the lower spine during adulthood and other spine problem

• sleep apnea

• weight gain

• speech and language problems

Individuals with proportionate short stature (PSS) may have poorly developed organs and pregnancy complications, such as respiratory problems. Delivery will normally be by cesarean section.

Outlook

Most people with short stature will have a normal life expectancy, and 90 percent of children who are small for their age at 2 years will "catch up" by adulthood.

The 10 percent who do not catch up are likely to have a condition such as fetal alcohol, Prader-Willi, or Down syndrome.

A person with achondroplasia can also expect a normal lifespan.

However, some serious conditions that are linked to some cases of short stature can be fatal.

[transgenderer]

Aluminum salt solutions are the most common antiperspirants in use today.[58] Several studies have shown that aluminum salts cause an obstruction of the distal sweat gland ducts.[59] A mechanism underlying this obstruction has been proposed: the metal ions precipitate with mucopolysaccharides, damaging epithelial cells along the lumen of the duct and forming a plug that blocks sweat output.[58] Sweat is still produced, as evidenced by the appearance of miliaria (prickly heat) during heat stress, with sweat building up behind the obstruction created by the metallic salt.[59] Normal sweat gland function returns with epidermal renewal, however, necessitating retreatment once or twice a week.[58]

your sweat ducts are full of sweat when youj wear antiperspirant....

[steeltypemutual]

i know the more official word is glycosaminoglycan but mucopolysaccharide is more fun to say

[dr-smitagoelhomeopathyclinic]

*Dr. Smita Goel Homeopathy Clinic*

www.thehomeopathyclinic.co.in

A person with short stature, or restricted growth, does not grow as tall as other people of the same gender, age, and ethnicity. The person's height is below the 3rd percentile.

Short stature can be a variant of normal growth, or it may indicate a disorder or condition.

Growth rate is an important indicator of overall health. Children who do not reach the 5th percentile by the age of 5 years are said to be small for gestational age (SGA). A pediatrician will look out for signs of "failure to thrive."

Early intervention can prevent future problems in many cases.

Normally, at 8 years of age, a child's arm span is around the same as their height. If these measurements are out of proportion, this may be a sign of disproportionate short stature (DSS), sometimes known as "dwarfism."

Fast facts on short stature

Here are some key points about short stature. More detail is in the main article.

• Short stature can happen for a wide range of reasons, including having small parents, malnutrition, and genetic conditions such as achondroplasia.

• Proportionate short stature (PSS) is when the person is small, but all the parts are in the usual proportions. In disproportionate short stature (DSS), the limbs may be small compared with the trunk.

• If short stature results from a growth hormone (GH) deficiency, GH treatment can often boost growth.

• Some people may experience long-term medical complications, but intelligence is not usually affected.

Causes

Growth depends on a complex range of factors, including genetic makeup, nutrition, and hormonal influences.

The most common cause of short stature is having parents whose height is below average, but around 5 percent of children with short stature have a medical condition.

Conditions that can underlie short stature include:

• Undernutrition, due to a disease or lack of nutrients

• Hypothyroidism, leading to a lack of growth hormone

• A tumor in the pituitary gland

• Diseases of the lungs, heart, kidneys, liver, or gastrointestinal tract

• Conditions that affect the production of collagen and other proteins

• Some chronic diseases, such as celiac disease and other inflammatory disorders

• Mitochondrial disease, which can affect the body in different ways, including growth

Sometimes, an injury to the head during childhood can lead to reduced growth.

A lack of growth hormone can also lead to delayed or absent sexual development.

Rheumatologic diseases, such as arthritis, are linked to short stature. This may happen because of the disease, or as a result of the glucocorticoid treatment, which can affect the release of growth hormone.

Disproportionate short stature (DSS) usually stems from a genetic mutation that affects the development of bone and cartilage and undermines physical growth.

The parents may not have short stature, but they may pass on a condition that is linked to DSS, such as achondroplasia, mucopolysaccharide disease, and spondyloepiphyseal dysplasia (SED).

Types

There are different types and causes of short stature, or restricted growth, and they will present differently. Because the range of conditions is so broad, restricted growth can be classified in various ways.

One categorization is:

• Variant restricted growth

• Proportionate short stature (PSS)

• Disproportionate short stature (DSS)

Each of these categories includes a number of types and causes of short stature.

Variant restricted growth

Sometimes a person is small but otherwise healthy. This can be referred to as variant restricted growth. It may happen for genetic or hormonal reasons.

If the parents are also small, this can be called familial short stature (FSS). If it stems from a hormonal issue, it is a constitutional delay in growth and adolescence (CDGA).

The limbs and the head develop in proportion with the spine, and the individual is otherwise healthy.

Growth happens throughout the body, so the legs, for example, are in proportion with the spine.

In most cases, the individual's parents are also small, but sometimes small stature happens because the body does not produce enough growth hormone (GH), or the body does not process growth hormone properly. This is known as GH insensitivity. Hypothyrodism can lead to low hormone production.

Growth hormone treatment during childhood may help.

Proportionate short stature (PSS)

Sometimes, overall growth is restricted, but the person's body is in proportion, and the individual has a related health problem. This is known as proportionate short stature (PSS).

If the individual is heavy for their height, this can suggest a hormone problem. The problem could be hypothyroidism, excess glucorticoid production, or too little GH.

A person who is small and their weight is low for their height may be experiencing malnutrition, or they may have a disorder that leads to malabsorption.

Whatever the underlying reason, if it affects overall growth, it may impact development in at least one body system, so treatment is needed.

During adulthood, a person with this type of restricted growth is more likely to experience:

• osteoporosis

• cardiovascular problems

• reduced muscle strength

Rarely, there may be cognitive problems, or problems with thinking. This depends on the cause of the short stature.

Disproportionate short stature (DSS)

Disproportionate short stature (DSS) is linked to a genetic mutation. The parents are usually of average height. As with other types of short stature, a range underlying causes is possible.

An individual with DSS will be small in height, and they will have other unusual physical features. These may be visible at birth, or they may develop in time as the infant develops.

Most individuals will have an average-sized trunk and short limbs, but some people may have a very short trunk and shortened, but disproportionately large limbs. Head size may be disproportionately large.

Intelligence or cognitive abilities are unlikely to be affected unless the person has hydrocephalus, or too much fluid around the brain.

Achondroplasia underlies around 70 percent of cases of DSS. It affects around 1 in 15,000 to 1 in 40,000 people.

Features include:

• an average-sized trunk

• short limbs, especially the upper arms and legs

• short fingers, possibly with a wide space between the middle and ring fingers

• limited mobility in the elbows

• a large head with a prominent forehead and flattened bridge of the nose

• bowed legs

• lordosis, a progressive development of a swayed lower back

• average adult height of 4 feet, or 122 cm

Hypochondroplasia is a mild form of achondroplasia. It may be difficult to differentiate between familial short stature and achondroplasia.

Achondroplasia and hypochondroplasia result from a genetic mutation.

Genetic conditions, such as Turner syndrome, Down syndrome, or Prader Willi syndrome, are also linked to DSS.

Diagnosis

Some types of short stature can be diagnosed at birth. In other cases, routine visits to a pediatrician should reveal any abnormal growth pattern.

The doctor will record the child's head circumference, height, and weight.

If the doctor suspects restricted growth, they will carry out a physical examination, look at the child's medical and family history, and possibly carry out some tests.

These may include:

An x-ray, to assess for problems with bone development

An insulin tolerance test, to check for a deficiency in the growth hormone insulin-like growth factor-1 (IGF-1).

In this test, insulin is injected into a vein, causing blood glucose levels to drop. Normally, this would trigger the pituitary gland to release growth hormone (GH). If GH levels are lower than normal, there may be a GH deficiency.

Other tests include:

• a thyroid-stimulating hormone test, to check for hypothyroidism

• a complete blood count, to test for anemia

• metabolic tests, to assess liver and kidney function

• erythrocyte sedimentation and C-reactive protein tests, to assess for inflammatory bowel disease

• urine tests can check for enzyme deficiency disorders

• tissue transglutinase and immunoglobulin A tests, for celiac disease

• imaging scans, such as an x-ray of the skeleton and the skull or an MRI, can detect problems with the pituitary gland or hypothalamus

• bone marrow or skin biopsies may help confirm conditions associated with short stature

Treatment

Treatment will depend on the cause of the short stature.

If there are signs of malnutrition, the child may need nutritional supplements or treatment for a bowel disorder or other condition that is preventing them from absorbing nutrients.

If growth is restricted or delayed because of a hormonal problem, GH treatment may be necessary.

Pediatric hormone treatment: In children who produce too little GH, a daily injection of hormone treatment may stimulate physical growth later in life. Medications, such as somatropin, may eventually add 4 inches, or 10 centimeters, to adult height.

Adult hormone treatment

: Treatment for adults can help protect against complications, for example, cardiovascular disease and low bone mineral density.

Somatropin, also known as recombinant GH, might be recommended for people who:

• have a severe growth hormone deficiency

• experience impaired quality of life

• are already receiving treatment for another pituitary hormone deficiency

Adult patients generally self-administer daily with an injection.

Adverse effects of somatropin include headache, muscle pain, edema, or fluid retention, problems with eyesight, joint pain, vomiting, and nausea.

The patient may receive treatment to control chronic conditions, such as heart disease, lung disease, and arthritis.

Treatment for DSS

As DSS often stems from a genetic disorder, treatment focuses mainly on the complications.

Some patients with very short legs may undergo leg lengthening. The leg bone is broken and then fixed into a special frame. The frame is adjusted daily to lengthen the bone.

This does not always work, it takes a long time, and there is a risk of complications, including:

• pain

• the bone forming badly or at an inappropriate rate

• infection

• deep vein thrombosis (DVT), a blood clot in a vein

Other possible surgical treatments include:

• use of growth plates, where metal staples are inserted into the ends of long bones where growth takes place, to help bones grow in the right direction

• inserting staples or rods to help the spine form the right shape

• increasing the size of the opening in the bones of the spine to reduce pressure on the spinal cord

Regular monitoring can reduce the risk of complications.

Complications

A person with DSS may experience a number of complications.

These include:

• arthritis later in life

• delayed mobility development

• dental problems

• bowed legs

• hearing problems and otitis media

• hydrocephalus, or too much fluid in the brain cavities

• hunching of the back

• limb problems

• swaying of the back

• narrowing of the channel in the lower spine during adulthood and other spine problem

• sleep apnea

• weight gain

• speech and language problems

Individuals with proportionate short stature (PSS) may have poorly developed organs and pregnancy complications, such as respiratory problems. Delivery will normally be by cesarean section.

Outlook

Most people with short stature will have a normal life expectancy, and 90 percent of children who are small for their age at 2 years will "catch up" by adulthood.

The 10 percent who do not catch up are likely to have a condition such as fetal alcohol, Prader-Willi, or Down syndrome.

A person with achondroplasia can also expect a normal lifespan.

However, some serious conditions that are linked to some cases of short stature can be fatal.

[aurasenceindia]

Hydrate Your Skin Naturally With Aloe Vera

Aloe Vera Body Moisturizer

In the ever-evolving world of skincare, one ingredient that continues to reign supreme is aloe vera. Celebrated for its healing properties and natural hydrating abilities, aloe vera has become the cornerstone of many skincare routines across the globe. Among the most sought-after products infused with this wonder plant is the aloe vera body moisturizer—a product known not just for its soothing effects but also for its ability to cater to all skin types. With the rising consumer preference for natural skincare solutions, aloe vera body moisturizers have found their rightful place on bathroom shelves and in daily self-care regimens.

The demand for skincare products that blend effectiveness with clean, botanical ingredients has led to a surge in aloe vera-based formulations. The aloe vera body moisturizer is one such product that goes beyond superficial hydration to deliver deep nourishment and protection. Whether you're combating dry patches, seasonal roughness, or simply looking to maintain radiant, supple skin, incorporating this product into your skincare arsenal is a smart and strategic move. Let us explore the science, benefits, and relevance of aloe vera body moisturizers, including why more consumers are making the switch to products that combine nature and science—like the one offered by Aurasence India.

The Science Behind Aloe Vera's Skin Benefits

Aloe vera, often referred to as the "plant of immortality," contains over 75 active compounds, including vitamins, enzymes, minerals, sugars, lignin, saponins, salicylic acids, and amino acids. These elements work synergistically to nourish and repair the skin. Vitamin A, C, and E in aloe vera provide antioxidant protection that helps to combat free radicals, which are a major contributor to premature aging. Enzymes such as bradykinase help reduce inflammation, while polysaccharides enhance moisture retention by forming a protective barrier on the skin.

Moreover, aloe vera has natural antimicrobial and antifungal properties, making it particularly effective for those with sensitive or acne-prone skin. Its high mucopolysaccharide content contributes to its excellent hydrating ability, making it a preferred base ingredient in body moisturizers. When applied topically, aloe vera penetrates the epidermis and hydrates the deeper layers of the skin, thereby supporting skin regeneration and enhancing elasticity.

The cooling nature of aloe vera also helps calm irritated skin, making it suitable for use after sun exposure or post hair removal. This wide-ranging functionality is what makes aloe vera body moisturizer a holistic skincare product suitable for year-round use, irrespective of climate or skin type.

Aloe Vera Body Moisturizer vs. Conventional Body Lotions

One might wonder: what sets an aloe vera body moisturizer apart from conventional body lotions? The primary difference lies in the formulation. Traditional body lotions often rely on mineral oils, synthetic fragrances, and chemical preservatives that can cause irritation or clog pores. On the other hand, an aloe vera body moisturizer emphasizes plant-based nourishment, lightweight texture, and deep hydration without compromising skin health.

Because aloe vera is a natural humectant, it draws moisture from the environment and locks it into the skin, thereby providing long-lasting hydration. Most conventional moisturizers might offer temporary softness, but aloe vera’s ability to support skin repair at a cellular level sets it apart. Additionally, it supports the skin’s natural barrier function, which is crucial for retaining moisture and defending against environmental pollutants.

Another key advantage is the minimal risk of allergic reactions. Since aloe vera is hypoallergenic and non-comedogenic, it suits individuals with reactive or sensitive skin. In contrast, body lotions laden with alcohols and artificial coloring can aggravate existing skin conditions, especially eczema or psoriasis.

Ideal for All Skin Types: A Versatile Solution

One of the most impressive aspects of an aloe vera body moisturizer is its adaptability to all skin types. For individuals with dry skin, the product provides intense hydration, softening rough patches and reducing flakiness. Its fast-absorbing nature ensures that the skin remains non-greasy yet nourished throughout the day.

People with oily or acne-prone skin also benefit greatly, thanks to aloe vera's anti-inflammatory and antimicrobial characteristics. Unlike heavy moisturizers that can clog pores and cause breakouts, aloe vera soothes inflammation and helps control excess oil production. Its lightweight texture makes it a staple for those who are often cautious about moisturizing.

Sensitive skin users often struggle to find a body moisturizer that doesn’t cause itching, redness, or irritation. Aloe vera, being naturally calming, reduces hypersensitivity and supports skin healing. Additionally, it’s gentle enough to be used after shaving or waxing, providing instant relief from razor burns or irritation.

For combination skin, aloe vera acts as a balancing agent—hydrating dry areas while calming oily zones. This versatility makes it a one-size-fits-all solution in a world where personalized skincare is becoming more important.

Seasonal Skincare Benefits

An aloe vera body moisturizer is not just a product for dry winters but a year-round skincare essential. During the colder months, the skin loses moisture rapidly due to indoor heating and harsh winds. Aloe vera, enriched with vitamins and antioxidants, counteracts this dehydration by locking in moisture and restoring suppleness.

In the summer, heat and sun exposure often lead to sunburn, rashes, and clogged pores. Aloe vera's cooling and soothing properties are ideal for calming sun-stressed skin. The lightweight consistency of aloe vera-based moisturizers ensures that they don’t feel sticky or greasy, even in humid conditions.

Monsoons bring with them a different set of skin challenges such as fungal infections and increased oiliness. The antibacterial and antifungal qualities of aloe vera make it perfect for this transitional period. Whether you’re layering under sunscreen or applying it as an after-sun treatment, aloe vera body moisturizer performs consistently across all seasons.

Real-World Testimonials and Dermatological Backing

The widespread acceptance of aloe vera body moisturizer isn’t just marketing hype; it’s backed by both dermatological studies and real-world user feedback. Numerous studies highlight aloe vera’s effectiveness in improving skin hydration and reducing redness. Clinical trials have demonstrated its potential in treating mild to moderate psoriasis and eczema, further validating its therapeutic value.

Consumers have also reported visible improvements in skin texture, tone, and overall appearance after consistent use. Testimonials frequently mention the reduction of dry patches, elimination of itchiness, and enhancement in skin glow. The key to these benefits lies in regular usage and the quality of the formulation.

High-quality products, like the ones offered by trusted skincare brands, typically include pure aloe vera extract without unnecessary fillers. These formulations preserve the plant’s efficacy and deliver consistent results. Dermatologists recommend aloe vera moisturizers for patients recovering from skin treatments such as chemical peels or laser therapy, thanks to their regenerative and healing properties.

Environmental and Ethical Appeal

Beyond personal skincare benefits, choosing an aloe vera body moisturizer is also a step toward environmental consciousness. Aloe vera is a sustainable crop that requires minimal water and thrives in arid regions. Responsible sourcing of aloe vera not only supports local farming communities but also reduces the ecological footprint compared to petroleum-based skincare ingredients.

Many aloe vera body moisturizers are cruelty-free and free from parabens, sulfates, and artificial colors. As consumer awareness about ethical beauty practices grows, demand for products that align with these values continues to surge. Aloe vera, being biodegradable and naturally derived, aligns perfectly with clean beauty standards.

Additionally, packaging innovation is making it easier for customers to choose products that are not only good for their skin but also for the planet. Recyclable tubes, minimalistic designs, and eco-friendly production processes are fast becoming the norm among premium brands that offer aloe vera-based moisturizers.

Aloe Vera Moisturizer in Daily Skincare Routines

Incorporating an aloe vera body moisturizer into your daily routine doesn’t require a complete overhaul. It works well as a post-shower hydrator, locking in moisture when the skin is still damp. For those who exfoliate regularly, it helps to soothe the skin and prevent post-exfoliation dryness.

Evening applications can support overnight skin repair, making it an ideal product to apply before bed. Athletes and fitness enthusiasts also find it beneficial post-workout, as it reduces sweat-induced irritation and refreshes the skin. For mothers and caregivers, the gentle formulation makes it suitable even for children’s sensitive skin.

Travelers often carry aloe vera moisturizers due to their multi-purpose nature. Whether you’re in dry airplane cabins or sunny beach destinations, this product delivers consistent hydration and relief. Over time, its inclusion in your skincare routine can significantly improve skin elasticity, radiance, and overall health.

Why Aurasence India’s Aloe Vera Moisturizer Stands Out

With numerous options in the market, choosing the right aloe vera body moisturizer can be overwhelming. However, Aurasence India has carved a niche for itself by offering a product that embodies purity, performance, and purpose. The Avec Aloe Vera Moisturizer from Aurasence combines organically grown aloe vera extract with nourishing agents that penetrate deeply and hydrate thoroughly without clogging pores.

What sets this product apart is its commitment to clean formulation. It is free from synthetic fragrances, harsh chemicals, and animal-derived ingredients. The result is a body moisturizer that caters to even the most sensitive skin while delivering long-lasting hydration and comfort.

Moreover, Aurasence India emphasizes quality control at every stage—from sourcing raw ingredients to the final packaging—ensuring that customers receive a product that is both safe and effective. The brand also focuses on sustainability and ethical practices, which adds another layer of credibility and trust for eco-conscious consumers.

Conclusion

Aloe vera body moisturizer is more than just a trend—it's a skincare essential that delivers both immediate relief and long-term benefits. From hydration and healing to anti-inflammatory and anti-aging effects, the humble aloe vera continues to prove its mettle in modern skincare. Its universal appeal, backed by science and loved by users across age groups, makes it an ideal choice for anyone seeking natural, effective skincare.

As skincare preferences shift toward cleaner, greener solutions, aloe vera stands tall as a timeless ingredient that meets today’s standards. For those looking to embrace the full potential of this botanical marvel, Aurasence India offers a trustworthy and high-quality option in the form of its Avec Aloe Vera Moisturizer. With its skin-friendly formulation and commitment to ethical practices, Aurasence India continues to set benchmarks in the world of natural skincare. Experience the difference today and let your skin thank you.

[vinarikhanhhoa]

Hướng Dẫn Sử Dụng Yến Sào Chưng Sẵn Đúng Cách Để Bồi Bổ Sức Khỏe Tối Ưu

Yến sào từ lâu đã được xem là "vàng trắng" trong thực phẩm bổ dưỡng, thường xuất hiện trong các bữa ăn cung đình xưa. Ngày nay, với nhịp sống hiện đại và nhu cầu chăm sóc sức khỏe ngày càng cao, yến sào chưng sẵn trở thành lựa chọn lý tưởng cho những ai bận rộn nhưng vẫn muốn duy trì chế độ dinh dưỡng lành mạnh.

Tuy nhiên, không phải ai cũng biết cách sử dụng yến sào chưng sẵn sao cho hiệu quả, hấp thu dưỡng chất tốt và tránh lãng phí. Bài viết dưới đây sẽ hướng dẫn bạn chi tiết từ cách dùng, thời điểm sử dụng đến những lưu ý quan trọng để yến chưng Khánh Hòa hay bất kỳ loại yến chưng sẵn nào phát huy tối đa công dụng.

1. Yến sào chưng sẵn là gì? Có gì khác biệt so với tổ yến thô?

1.1. Định nghĩa yến sào chưng sẵn

Yến sào chưng sẵn là sản phẩm được chế biến từ tổ yến đã qua làm sạch và được nấu chín với nước tinh khiết cùng một số nguyên liệu khác như đường phèn, hạt sen, táo đỏ, hoặc gừng. Sản phẩm này thường được đóng lọ và tiệt trùng sẵn để bảo quản lâu dài.

Khác với tổ yến thô hoặc yến tinh chế, yến sào chưng sẵn mang lại sự tiện lợi vượt trội: không cần mất thời gian ngâm, nhặt lông, chưng cách thủy… Bạn có thể dùng ngay mà vẫn đảm bảo giá trị dinh dưỡng.

1.2. Ưu điểm vượt trội của yến sào chưng sẵn

Tiện lợi cho người bận rộn

Định lượng sẵn, tránh lãng phí

Giữ được phần lớn dưỡng chất của tổ yến nguyên chất

Đa dạng hương vị dễ sử dụng

Đặc biệt, nhiều sản phẩm yến chưng Khánh Hòa còn được chứng nhận an toàn thực phẩm, có nguồn gốc từ vùng nuôi yến nổi tiếng với chất lượng hàng đầu Việt Nam.

2. Tác dụng nổi bật của yến sào chưng sẵn với sức khỏe

2.1. Tăng cường hệ miễn dịch

Các acid amin quý như arginine, cystine, lysine trong yến sào giúp cơ thể chống lại vi khuẩn, tăng sức đề kháng hiệu quả.

2.2. Cải thiện chức năng hô hấp

Người thường xuyên viêm họng, ho lâu ngày, suy nhược phổi sẽ thấy rõ sự cải thiện khi dùng yen chung san thường xuyên, nhờ chất mucopolysaccharide trong yến giúp làm dịu niêm mạc đường thở.

2.3. Làm đẹp da, chống lão hóa

Thành phần collagen tự nhiên và acid sialic có trong yến chưng Khánh Hòa giúp da căng mịn, phục hồi tổn thương, đồng thời làm chậm quá trình lão hóa.

2.4. Tốt cho phụ nữ mang thai và sau sinh

Yến sào hỗ trợ tăng cường sức khỏe thai nhi, đồng thời giúp mẹ hồi phục nhanh sau sinh, giảm tình trạng thiếu sữa, mệt mỏi.

2.5. Hỗ trợ trí nhớ và giấc ngủ

Với người lớn tuổi hoặc học sinh, sinh viên, yến chưng giúp tăng cường tuần hoàn máu não, giảm căng thẳng và cải thiện giấc ngủ tự nhiên.

3. Hướng dẫn sử dụng yến sào chưng sẵn đúng cách

3.1. Liều lượng khuyến nghị

Người lớn: 1 hũ 70ml/ngày, dùng cách ngày hoặc liên tục trong 10–30 ngày tùy mục đích sử dụng.

Trẻ em từ 2 tuổi trở lên: ½ hũ/lần, 2–3 lần/tuần.

Phụ nữ mang thai: Bắt đầu từ tháng thứ 4, nên dùng 1 hũ cách 2 ngày.

3.2. Thời điểm dùng yến hiệu quả nhất

Sáng sớm khi bụng đói: Cơ thể hấp thu tốt nhất.

Buổi tối trước khi ngủ 30 phút: Giúp ngủ ngon, thư giãn thần kinh.

Tránh dùng yến ngay sau bữa ăn no vì sẽ giảm khả năng hấp thụ.

3.3. Cách dùng và bảo quản

Lắc nhẹ trước khi uống để dưỡng chất hòa tan đều.

Dùng ngay sau khi mở nắp, phần còn lại cần bảo quản tủ lạnh và sử dụng trong vòng 24 giờ.

Không nên hâm nóng bằng lò vi sóng. Nếu thích dùng ấm, có thể ngâm lọ yến vào nước ấm 50–60 độ C trong 3–5 phút.

4. Những sai lầm thường gặp khi dùng yến sào chưng sẵn

4.1. Lạm dụng với liều lượng quá nhiều

Nhiều người nghĩ dùng nhiều sẽ bổ hơn, nhưng điều này hoàn toàn sai. Việc dùng quá liều có thể gây đầy bụng, nóng người, thậm chí rối loạn tiêu hóa.

4.2. Dùng yến sào chưng sẵn kém chất lượng

Một số sản phẩm trên thị trường chỉ có tỷ lệ yến rất thấp hoặc pha tạp phụ gia, đường hóa học. Lời khuyên là nên chọn sản phẩm có thương hiệu rõ ràng, đặc biệt là các loại yến chưng Khánh Hòa từ các đơn vị uy tín, có công bố hàm lượng yến cụ thể trên bao bì.

4.3. Dùng yến khi cơ thể đang cảm cúm, sốt cao

Yến có tính mát nên nếu đang cảm lạnh, ho nhiều đờm thì không nên dùng, dễ làm tình trạng nặng thêm. Chỉ nên sử dụng khi cơ thể đã ổn định.

5. Gợi ý một số sản phẩm yến sào chưng sẵn chất lượng cao

Tên sản phẩmTỷ lệ yếnDung tíchHương vịXuất xứ

Yến chưng Khánh Hòa 12% 12% 70ml Đường phèn Nha Trang – Khánh Hòa

Yến sào chưng sẵn SEN 10% 70ml Táo đỏ, hạt sen Việt Nam

Yến Ngọc Sâm Premium 15% 75ml Không đường TP.HCM

6. Đối tượng nào nên và không nên dùng yến sào chưng sẵn?

6.1. Nên dùng:

Người mới ốm dậy, thể trạng yếu

Trẻ em còi xương, kém ăn

Phụ nữ có thai hoặc sau sinh

Người làm việc trí óc căng thẳng

Người già suy nhược cơ thể

6.2. Không nên dùng:

Người đang cảm lạnh, tiêu chảy

Trẻ dưới 12 tháng tuổi

Người dị ứng protein từ động vật

7. Kết luận: Yến sào chưng sẵn – “Thần dược” hiện đại nếu sử dụng đúng cách

Yến sào chưng sẵn là giải pháp bổ sung dinh dưỡng lý tưởng trong thời đại bận rộn. Tuy nhiên, để phát huy tối đa hiệu quả, người dùng cần hiểu rõ về liều lượng, thời điểm và cách bảo quản. Đừng chỉ chọn theo mẫu mã đẹp mắt, hãy ưu tiên các sản phẩm có xuất xứ rõ ràng, như yến chưng Khánh Hòa – biểu tượng cho chất lượng và uy tín.

Câu hỏi thường gặp (FAQ)

1. Yến sào chưng sẵn có dùng được cho người tiểu đường không?

Có thể, nhưng cần chọn loại yến chưng không đường hoặc dùng sản phẩm có lượng đường rất thấp. Tham khảo ý kiến bác sĩ trước khi dùng.

2. Mỗi ngày có thể dùng bao nhiêu hũ yến sào chưng sẵn?

Tối đa 1 hũ/ngày cho người trưởng thành. Dùng đúng liều sẽ mang lại hiệu quả tốt hơn lạm dụng.

3. Trẻ nhỏ có thể uống yến sào chưng sẵn không?

Từ 2 tuổi trở lên có thể dùng, nhưng với liều lượng ít và ưu tiên loại có hương vị nhẹ, ít đường.

[summer-starry-dawn]

Pharmacie : Traitement des troubles thrombo-emboliques

Antiagrégants plaquettaires

AINS : Indiqué dans la prévention d'épisodes thrombo-emboliques des suites d’IDM.

- Aspirine à faible dose : Par inhibition de la COX plaquettaire et donc diminution de la synthèse de la Thromboxane pro-agrégant, et préservation partielle de la COX endothéliale responsable de la Prostacycline (PGI2) à effet anti-agrégant plaquettaire.

- Flubipogène à faible dose : prescrit si l’Aspirine est contre-indiquée. Indications

Dipyridamol : Inhibition de la recapture de l’Adénosine, associé à l’Aspirine.

Ticlopidine : Opposition aux effets de l’ADP. Grande toxicité hématologique.

Clopidogrel : Dérivé de la Ticlopidine, avec une meilleure tolérance digestive et hématologique. Indiqué dans la prévention des complications liées à l’athérosclérose

Anti-GP IIb-IIIa : Abciximab

Fibrinolytiques

Urokinase ;

Streptokinase ;

Alteplase.

Mode d’action : Activation de la transformation du plasminogène en plasmine.

Indications : Embolie pulmonaire ; IDM en phase aiguë.

Antidote : Acide tranexamique.

Effets indésirables : Hémorragies et risque de choc anaphylactique.

Anticoagulants

Héparines

Traitements préventifs et curatifs des manifestations thrombo-emboliques. Leur antidote est le sulfate de protamine. Ce sont des mucopolysaccharides dont l’unité essentielle est l’unité penta-saccharidique. On distingue deux types d'héparines :

Les Héparines non fractionnées (HNF) agissent par accélération de l’inhibition de la thrombine (inhibition de l’extension de la thrombose) et du facteur Xa (inhibition de la formation de la thrombose) par l'intermédiaire de l’antithrombine III. Le rapport anti-Xa/anti-IIa = 1. Elles sont administrées par voie sous-cutanée (détruite per os) avec une biodisponibilité de 30 % et une demi-vie courte et variable. Leurs principales EI sont : Le smanifestations hémorragiques, les thrombopénies induites par l'héparine (TIH) graves, et la nécrose au site d'injection.

On a ensuite les Héparines de bas poids moléculaire (HBPM), qui ont le même mode d’action, sauf qu’elles ont une faible activité anti-IIa et une activité anti-Xa variable (rapport anti-Xa/anti-IIa > 1). Elles sont administrées par voie sous-cutanée, avec une biodisponibilité de 90 % et une demi-vie plus longue. Leur élimination est rénale. Avec les HBPM, les hémorragies sont moins fréquentes, et les TIH sont modérées.

Les deux types d’héparines ne traversent pas la barrière foeto-placentaire.

Surveillance :

o Numération plaquettaire (avant et après traitement) ;

o Surveillance biologique : TCA et activité anti-Xa ;

o Surveillance clinique (hémorragies) ;

o Ne pas administrer en IM (nécrose) ;

o Non conseillés au T1 de la grossesse.

Interactions médicamenteuses : augmentation du risque hémorragique avec les AINS et le Clopidogrel.

AVK

Anticoagulants indiqués en relai avec l’héparinothérapie, et dans la prévention des thromboses veineuses et artérielles.

Ils agissent par inhibition de la synthèse des facteurs vitamine K-dépendants par inhibition de deux enzymes.

=> La vitamine K (Phytoménadione) est indispensable à la synthèse des facteurs II, VII, IX et X par transformation du glutamate de leur extrémité N-terminale en acide γ-carboxy-glutamique.

Le délai d'action des AVK est variable, mais est toujours long. Ils ne sont donc pas utilisés en situation d'urgence. Administrés par voie orale, forte fixation aux protéines plasmatiques, demi-vie variable de 12 à 45 h, durée d’action de 1 à 4 jours, index thérapeutique étroit, métabolisé par le CYP2C9.

On distingue deux types d'AVK ; les AVK coumariniques, et les AVK dérivés de l'indandione.

Effets indésirable : Ils comprennent manifestations hémorragiques, et allergies pour les dérivés de l’indandiones.

Surveillance et précautions d’emploi : On a une grande variabilité dose – réponse inter- et intra-patient, donc c'est très important !!

Calcul de l’INR ;

Contre-indiqués en cas de grossesse (tératogénicité et risque hémorragique).

Facteurs de variabilité :

Génétique : mutation du CYP2C9 ou de la vitamine K époxyde réductase (VKORC1) ;

Alimentation : diminution des effets des AVK en cas d’alimentation riche en vitamine K.

Situation physiopathologique.

Interactions médicamenteuses

Salicylés à forte dose : inhibition de l’agrégation plaquettaire et déplacement de la l’AVK de sa liaison aux protéines plasmatiques ;

Inducteurs enzymatiques et inhibiteurs enzymatiques

Schéma thérapeutique curatif

Schéma thérapeutique prophylaxie

[smalife1234]

Today is World Sanfilippo Awareness Day! That's right I said it!

National Sanfilippo Awareness Day is so important! So spread the word! The Cure Sanfilippo Foundation runs this event to support those living with Sanfilippo syndrome or a parent who has a child with Sanfilippo!

To give you all the background on this condition

(I got my Information here: https://teamsanfilippo.org/what-is-sanfilippo-syndrome)

Sanfilippo syndrome is a genetic error of metabolism. It is a mucopolysaccharidosis, an MPS disorder, MPS. Mucopolysaccharides are long chains of sugar molecules, which are used in building connective tissues. When the body is finished using these molecules, it breaks them down with enzymes and disposes of them. Children with Sanfilippo syndrome are missing or are deficient in the enzyme to break down the molecules. Instead, the body stores these molecules in the cells. This storage causes progressive damage.

There are four different types of Sanfilippo syndrome. Each type is different and named according to which enzyme is missing or defective.

Sanfilippo Type A is the most common. It is considered the most severe type with earlier death than the others. These children are deficient in the enzyme Heparan N-sulfatase.

Sanfilippo Type B is the second most common. This is the result of a deficiency in N-acetyl-alpha-D-glucosaminidase.

Sanfilippo Type C is caused by a deficiency in acetyl-CoAlpha-glucosaminide acetyltransferase.

Sanfilippo Type D is caused by a deficiency in N-acetylglucosamine 6-sulfatase.

Sanfilippo syndrome was first described in 1963 by Dr. Sylvester Sanfilippo and is considered rare, with an occurrence of 1 in every 70,000 births. It is an autosomal recessive hereditary disorder, which means, both parents must be carriers in order for the child to be affected. There is a one in four chance of having a child born with Sanfilippo syndrome. There is a two in three chance that unaffected children will be carriers.

Sanfilippo syndrome is a progressive disorder, meaning that at birth the children appear typical and do not show signs of the disorder. As the disease progresses, the children degenerate, losing the ability to speak, walk, eat, and eventually lose their lives.

In the first stage of the disorder, it is noticed that the child lags and develops sleep and behavioral issues; most have frequent ear and or throat infections and often recurrent loose bowels. The child may also have a larger-than-average head size.

In the second stage, the child may become extremely active, restless, and often have very difficult behavior. Vision becomes an issue with many at this stage as well. Some children have severe sleep disturbances. Many like to chew on their hands and clothing. Language and understanding will gradually become lost. Many lose their swallowing ability and begin eating pureed foods and or move to receive a feeding tube. There are many documented cases of suspected intracranial pressure as well in Sanfilippo children. This is usually managed by the addition of a drug generically called Diamox ( a diuretic for removing fluid from the brain) or inserting a shunt if the child is young enough to undergo surgery.

In the third stage, the child begins to slow down. They have difficulty walking, falling often eventually losing the ability to walk altogether. Movement disorders (dystonia, myoclonus, etc. ) and contractures of hands, fingers, and other limbs can also occur.

Most children do experience seizures at some point, joint stiffness, upper respiratory infections, hearing loss, dementia, hyperactivity, aggressive behavior, incontinence, bowel issues of both loose and or compacted stools, severe intellectual impairment, partial paralysis, growth retardation, and vision impairment.

The current life expectancy is 10-20 years.

This is a horrible disease to live with! And it is so important that we spread awareness on this cause! November 16th is that day! The Cure Sanfilippo Foundation is doing so by creating shirts that show you care and support the worldwide foundation of Sanfilippo.

World Sanfilippo Awareness Day is about spreading awareness and sparking conversations globally about Sanfilippo Syndrome, a disease few have heard of. This special day of Awareness is in honor of the children around the world living with Sanfilippo Syndrome today, and those who have passed away. It also honors the families of these precious children.

The logo, showing the parent and child holding hands, pays tribute to the special love and bond of parent and child. Any parent can relate to the precious years you are able to hold your little one's hand, and it has special meaning for a parent of a child with Sanfilippo Syndrome.

Let, 's go spread awareness! Most importantly, I support the foundations that are trying to make a difference in the lives of people living with Sanfilippo or people who care for the person of Sanfillpo; my heart goes out to all those living with Sanfillipo and those who are caregivers.

Happy National Sanfilippo Awareness Day 💜💜💜!

Img desc #1: doc is seen smiling while wearing a dark blue short-sleeved shirt and green skinny jeans. She is on a platform where beautiful trees can be seen behind her with unicorns, rainbows, and purple heart emojis all representing Sanfilippo syndrome!

[als145]

Today is World Sanfilippo Awareness Day! That's right I said it!

National Sanfilippo Awareness Day is so important! So spread the word! The Cure Sanfilippo Foundation runs this event to support those living with Sanfilippo syndrome or a parent who has a child with Sanfilippo!

To give you all the background on this condition

(I got my Information here: https://teamsanfilippo.org/what-is-sanfilippo-syndrome)

Sanfilippo syndrome is a genetic error of metabolism. It is a mucopolysaccharidosis, an MPS disorder, MPS. Mucopolysaccharides are long chains of sugar molecules, which are used in building connective tissues. When the body is finished using these molecules, it breaks them down with enzymes and disposes of them. Children with Sanfilippo syndrome are missing or are deficient in the enzyme to break down the molecules. Instead, the body stores these molecules in the cells. This storage causes progressive damage.

There are four different types of Sanfilippo syndrome. Each type is different and named according to which enzyme is missing or defective.

Sanfilippo Type A is the most common. It is considered the most severe type with earlier death than the others. These children are deficient in the enzyme Heparan N-sulfatase.

Sanfilippo Type B is the second most common. This is the result of a deficiency in N-acetyl-alpha-D-glucosaminidase.

Sanfilippo Type C is caused by a deficiency in acetyl-CoAlpha-glucosaminide acetyltransferase.

Sanfilippo Type D is caused by a deficiency in N-acetylglucosamine 6-sulfatase.

Sanfilippo syndrome was first described in 1963 by Dr. Sylvester Sanfilippo and is considered rare, with an occurrence of 1 in every 70,000 births. It is an autosomal recessive hereditary disorder, which means, both parents must be carriers in order for the child to be affected. There is a one in four chance of having a child born with Sanfilippo syndrome. There is a two in three chance that unaffected children will be carriers.

Sanfilippo syndrome is a progressive disorder, meaning that at birth the children appear typical and do not show signs of the disorder. As the disease progresses, the children degenerate, losing the ability to speak, walk, eat, and eventually lose their lives.

In the first stage of the disorder, it is noticed that the child lags and develops sleep and behavioral issues; most have frequent ear and or throat infections and often recurrent loose bowels. The child may also have a larger-than-average head size.

In the second stage, the child may become extremely active, restless, and often have very difficult behavior. Vision becomes an issue with many at this stage as well. Some children have severe sleep disturbances. Many like to chew on their hands and clothing. Language and understanding will gradually become lost. Many lose their swallowing ability and begin eating pureed foods and or move to receive a feeding tube. There are many documented cases of suspected intracranial pressure as well in Sanfilippo children. This is usually managed by the addition of a drug generically called Diamox ( a diuretic for removing fluid from the brain) or inserting a shunt if the child is young enough to undergo surgery.

In the third stage, the child begins to slow down. They have difficulty walking, falling often eventually losing the ability to walk altogether. Movement disorders (dystonia, myoclonus, etc. ) and contractures of hands, fingers, and other limbs can also occur.

Most children do experience seizures at some point, joint stiffness, upper respiratory infections, hearing loss, dementia, hyperactivity, aggressive behavior, incontinence, bowel issues of both loose and or compacted stools, severe intellectual impairment, partial paralysis, growth retardation, and vision impairment.

The current life expectancy is 10-20 years.

This is a horrible disease to live with! And it is so important that we spread awareness on this cause! November 16th is that day! The Cure Sanfilippo Foundation is doing so by creating shirts that show you care and support the worldwide foundation of Sanfilippo.

World Sanfilippo Awareness Day is about spreading awareness and sparking conversations globally about Sanfilippo Syndrome, a disease few have heard of. This special day of Awareness is in honor of the children around the world living with Sanfilippo Syndrome today, and those who have passed away. It also honors the families of these precious children.

The logo, showing the parent and child holding hands, pays tribute to the special love and bond of parent and child. Any parent can relate to the precious years you are able to hold your little one's hand, and it has special meaning for a parent of a child with Sanfilippo Syndrome.

Let's go spread awareness! Most importantly, I support the foundations that are trying to make a difference in the lives of people living with Sanfilippo or people who care for the person of Sanfillpo; my heart goes out to all those living with Sanfillipo and those who are caregivers.

Happy national Sanfilippo awareness day!

[susu-0]

How to Fade Acne Scars

How to Fade Red Acne Marks: To reduce red acne marks, use products that contain anti-inflammatory ingredients, vasoconstrictors, and ingredients that promote blood circulation. These can help speed up the fading process of red marks.

Key soothing and anti-inflammatory ingredients include bisabolol, niacinamide, onion extract, centella asiatica extract, purslane extract, salicin (from willow bark extract), and olive leaf extract.

Note: Prioritize treating active acne! Many acne treatments or skincare products contain anti-inflammatory ingredients, which can also help reduce acne marks. Ingredients that help constrict capillaries include rutoside compounds (glucosylrutin, troxerutin), horse chestnut extract, mucopolysaccharides (MPS), and onion extract.

How to Fade Dark Acne Marks: To reduce dark acne marks, use products with anti-inflammatory properties that inhibit melanin production and accelerate skin metabolism, which can help speed up the fading process.

Fading Melanin: Dark acne marks are caused by post-inflammatory hyperpigmentation (PIH), where melanin deposits due to inflammation. The more severe the inflammation, the harder it is to fade dark marks.

Whitening Ingredients: Niacinamide, Vitamin C, arbutin, licorice extract, and tea extract are effective.

Exfoliating and Speeding Up Melanin Metabolism: Retinoic acid and its derivatives, as well as alpha hydroxy acids (AHAs), can help.

Sun Protection: Not using sunscreen can cause red acne marks to turn into dark ones, making them harder to remove. You can choose between physical and chemical sunscreens.

How to Fade Acne Pits: Acne pits and scars affect the dermis layer of the skin, resulting from significant damage to the skin's basement membrane, making them irreversible. For such cases, it's recommended to consult a professional dermatologist for treatments that may include collagen or hyaluronic acid injections.

Prevention is Key: Preventing the formation of acne pits is closely related to managing inflammation early. It’s important to treat red and dark acne marks promptly and avoid squeezing pimples.

Acne Mark Q&A:

Will acne marks naturally fade in 3-6 months? This depends on the size, depth, and severity of the acne, as well as your skin tone. If you address inflammation early, red marks are generally easier to fade.

Does the size of acne affect how long marks last? Yes, larger and deeper pimples tend to leave more stubborn marks. The larger the acne, the wider the area of skin it damages. The deeper the acne, the more it stimulates melanin production in the deeper layers of the skin, which takes longer to metabolize and fade.

[aionevn]

Vây Cánh Vi Cá Mập Nguyên Vây là gì?

Vây Cánh Vi Cá Mập Nguyên Vây: là một bộ phận của loài cá Mập được các ngư dân sau khi đánh bắt tiến hành chọn lọc tách lấy làm sạch, loại vi cá nguyên vây đuôi này có dạng hình tam giác, có rất ít mô cơ, có màng, bao gồm một bó sợi collagen lây lan ra như một nang quạt.

Vi cá mập có tính hiền, vị giòn của các mô sụn, là loại thực phẩm có giá thành đắt đỏ, mang đến nhiều lợi ích cho sức khỏe, dùng để chế biến các món ăn thơm ngon, bổ dưỡng, giúp hỗ trợ điều trị các bệnh về xương khớp, vi cá cũng có tác dụng bảo vệ giác mạc mắt, tránh khô mắt, cải thiện tình trạng bệnh liên quan đến mắt.

Ngoài ra sụn vi cá mập có chứa nhiều protein, collagen, chondroitin sulfate và các loại carbohydrate phức tạp gọi là mucopolysaccharides, những chất này có vai trò quan trọng trong việc duy trì và phục hồi các mô liên kết trong cơ thể như xương, sụn, dây chằng, gân và da.

Chế biến làm món gì ngon?

♥ Gợi ý đến bạn 1 số món ngon Vây Cánh Vi Cá Mập như: món súp vi cá mập, vi cá mập xào trứng gà, vi cá mập hầm gà ác, vi cá mập nấu cháo…đây là món ăn góp phần làm “sang chảnh” những bữa ăn, bữa tiệc cùng gia đình và bạn bè mang đến cho bạn những bữa ăn thơm ngon, giàu dinh dưỡng và an lành cho sức khỏe.

Giá trị dinh dưỡng và lợi ích gì khi ăn?

Vây Cánh Vi Cá Mập không chỉ là món ăn ngon mà còn là một loại thực phẩm biển giàu dinh dưỡng và có một số lợi ích sức khỏe, bao gồm:

Nguồn cung cấp chất đạm giàu, giúp xây dựng cơ bắp, tăng cường sức mạnh và sự phát triển của cơ thể. Chất béo omega-3: Vi cá mập chứa nhiều chất béo omega-3, đặc biệt là axit docosahexaenoic (DHA) và axit eicosapentaenoic (EPA), giúp cải thiện sức khỏe tim mạch và chức năng não.

Cung cấp các vitamin như vitamin B12, D, A và khoáng chất như sắt, kẽm, magiê và kali, giúp duy trì các chức năng cơ bản trong cơ thể và hỗ trợ hệ thống miễn dịch. Cung cấp protein và các chất dinh dưỡng quan trọng khác, giúp trẻ em và người trưởng thành phát triển cơ thể toàn diện.

[dr-smita-goel-homeopathy-clinic]

*Dr. Smita Goel Homeopathy Clinic*

www.thehomeopathyclinic.co.in

A person with short stature, or restricted growth, does not grow as tall as other people of the same gender, age, and ethnicity. The person's height is below the 3rd percentile.

Short stature can be a variant of normal growth, or it may indicate a disorder or condition.

Growth rate is an important indicator of overall health. Children who do not reach the 5th percentile by the age of 5 years are said to be small for gestational age (SGA). A pediatrician will look out for signs of "failure to thrive."

Early intervention can prevent future problems in many cases.

Normally, at 8 years of age, a child's arm span is around the same as their height. If these measurements are out of proportion, this may be a sign of disproportionate short stature (DSS), sometimes known as "dwarfism."

Fast facts on short stature

Here are some key points about short stature. More detail is in the main article.

• Short stature can happen for a wide range of reasons, including having small parents, malnutrition, and genetic conditions such as achondroplasia.

• Proportionate short stature (PSS) is when the person is small, but all the parts are in the usual proportions. In disproportionate short stature (DSS), the limbs may be small compared with the trunk.

• If short stature results from a growth hormone (GH) deficiency, GH treatment can often boost growth.

• Some people may experience long-term medical complications, but intelligence is not usually affected.

Causes

Growth depends on a complex range of factors, including genetic makeup, nutrition, and hormonal influences.

The most common cause of short stature is having parents whose height is below average, but around 5 percent of children with short stature have a medical condition.

Conditions that can underlie short stature include:

• Undernutrition, due to a disease or lack of nutrients

• Hypothyroidism, leading to a lack of growth hormone

• A tumor in the pituitary gland

• Diseases of the lungs, heart, kidneys, liver, or gastrointestinal tract

• Conditions that affect the production of collagen and other proteins

• Some chronic diseases, such as celiac disease and other inflammatory disorders

• Mitochondrial disease, which can affect the body in different ways, including growth

Sometimes, an injury to the head during childhood can lead to reduced growth.

A lack of growth hormone can also lead to delayed or absent sexual development.

Rheumatologic diseases, such as arthritis, are linked to short stature. This may happen because of the disease, or as a result of the glucocorticoid treatment, which can affect the release of growth hormone.

Disproportionate short stature (DSS) usually stems from a genetic mutation that affects the development of bone and cartilage and undermines physical growth.

The parents may not have short stature, but they may pass on a condition that is linked to DSS, such as achondroplasia, mucopolysaccharide disease, and spondyloepiphyseal dysplasia (SED).

Types

There are different types and causes of short stature, or restricted growth, and they will present differently. Because the range of conditions is so broad, restricted growth can be classified in various ways.

One categorization is:

• Variant restricted growth

• Proportionate short stature (PSS)

• Disproportionate short stature (DSS)

Each of these categories includes a number of types and causes of short stature.

Variant restricted growth

Sometimes a person is small but otherwise healthy. This can be referred to as variant restricted growth. It may happen for genetic or hormonal reasons.

If the parents are also small, this can be called familial short stature (FSS). If it stems from a hormonal issue, it is a constitutional delay in growth and adolescence (CDGA).

The limbs and the head develop in proportion with the spine, and the individual is otherwise healthy.

Growth happens throughout the body, so the legs, for example, are in proportion with the spine.

In most cases, the individual's parents are also small, but sometimes small stature happens because the body does not produce enough growth hormone (GH), or the body does not process growth hormone properly. This is known as GH insensitivity. Hypothyrodism can lead to low hormone production.

Growth hormone treatment during childhood may help.

Proportionate short stature (PSS)

Sometimes, overall growth is restricted, but the person's body is in proportion, and the individual has a related health problem. This is known as proportionate short stature (PSS).

If the individual is heavy for their height, this can suggest a hormone problem. The problem could be hypothyroidism, excess glucorticoid production, or too little GH.

A person who is small and their weight is low for their height may be experiencing malnutrition, or they may have a disorder that leads to malabsorption.

Whatever the underlying reason, if it affects overall growth, it may impact development in at least one body system, so treatment is needed.

During adulthood, a person with this type of restricted growth is more likely to experience:

• osteoporosis

• cardiovascular problems

• reduced muscle strength

Rarely, there may be cognitive problems, or problems with thinking. This depends on the cause of the short stature.

Disproportionate short stature (DSS)

Disproportionate short stature (DSS) is linked to a genetic mutation. The parents are usually of average height. As with other types of short stature, a range underlying causes is possible.

An individual with DSS will be small in height, and they will have other unusual physical features. These may be visible at birth, or they may develop in time as the infant develops.

Most individuals will have an average-sized trunk and short limbs, but some people may have a very short trunk and shortened, but disproportionately large limbs. Head size may be disproportionately large.

Intelligence or cognitive abilities are unlikely to be affected unless the person has hydrocephalus, or too much fluid around the brain.

Achondroplasia underlies around 70 percent of cases of DSS. It affects around 1 in 15,000 to 1 in 40,000 people.

Features include:

• an average-sized trunk

• short limbs, especially the upper arms and legs

• short fingers, possibly with a wide space between the middle and ring fingers

• limited mobility in the elbows

• a large head with a prominent forehead and flattened bridge of the nose

• bowed legs

• lordosis, a progressive development of a swayed lower back

• average adult height of 4 feet, or 122 cm

Hypochondroplasia is a mild form of achondroplasia. It may be difficult to differentiate between familial short stature and achondroplasia.

Achondroplasia and hypochondroplasia result from a genetic mutation.

Genetic conditions, such as Turner syndrome, Down syndrome, or Prader Willi syndrome, are also linked to DSS.

Diagnosis

Some types of short stature can be diagnosed at birth. In other cases, routine visits to a pediatrician should reveal any abnormal growth pattern.

The doctor will record the child's head circumference, height, and weight.

If the doctor suspects restricted growth, they will carry out a physical examination, look at the child's medical and family history, and possibly carry out some tests.

These may include:

An x-ray, to assess for problems with bone development

An insulin tolerance test, to check for a deficiency in the growth hormone insulin-like growth factor-1 (IGF-1).

In this test, insulin is injected into a vein, causing blood glucose levels to drop. Normally, this would trigger the pituitary gland to release growth hormone (GH). If GH levels are lower than normal, there may be a GH deficiency.

Other tests include:

• a thyroid-stimulating hormone test, to check for hypothyroidism

• a complete blood count, to test for anemia

• metabolic tests, to assess liver and kidney function

• erythrocyte sedimentation and C-reactive protein tests, to assess for inflammatory bowel disease

• urine tests can check for enzyme deficiency disorders

• tissue transglutinase and immunoglobulin A tests, for celiac disease

• imaging scans, such as an x-ray of the skeleton and the skull or an MRI, can detect problems with the pituitary gland or hypothalamus

• bone marrow or skin biopsies may help confirm conditions associated with short stature

Treatment

Treatment will depend on the cause of the short stature.

If there are signs of malnutrition, the child may need nutritional supplements or treatment for a bowel disorder or other condition that is preventing them from absorbing nutrients.

If growth is restricted or delayed because of a hormonal problem, GH treatment may be necessary.

Pediatric hormone treatment: In children who produce too little GH, a daily injection of hormone treatment may stimulate physical growth later in life. Medications, such as somatropin, may eventually add 4 inches, or 10 centimeters, to adult height.

Adult hormone treatment

: Treatment for adults can help protect against complications, for example, cardiovascular disease and low bone mineral density.

Somatropin, also known as recombinant GH, might be recommended for people who:

• have a severe growth hormone deficiency

• experience impaired quality of life

• are already receiving treatment for another pituitary hormone deficiency

Adult patients generally self-administer daily with an injection.

Adverse effects of somatropin include headache, muscle pain, edema, or fluid retention, problems with eyesight, joint pain, vomiting, and nausea.

The patient may receive treatment to control chronic conditions, such as heart disease, lung disease, and arthritis.

Treatment for DSS

As DSS often stems from a genetic disorder, treatment focuses mainly on the complications.

Some patients with very short legs may undergo leg lengthening. The leg bone is broken and then fixed into a special frame. The frame is adjusted daily to lengthen the bone.

This does not always work, it takes a long time, and there is a risk of complications, including:

• pain

• the bone forming badly or at an inappropriate rate

• infection

• deep vein thrombosis (DVT), a blood clot in a vein

Other possible surgical treatments include:

• use of growth plates, where metal staples are inserted into the ends of long bones where growth takes place, to help bones grow in the right direction

• inserting staples or rods to help the spine form the right shape

• increasing the size of the opening in the bones of the spine to reduce pressure on the spinal cord

Regular monitoring can reduce the risk of complications.

Complications

A person with DSS may experience a number of complications.

These include:

• arthritis later in life

• delayed mobility development

• dental problems

• bowed legs

• hearing problems and otitis media

• hydrocephalus, or too much fluid in the brain cavities

• hunching of the back

• limb problems

• swaying of the back

• narrowing of the channel in the lower spine during adulthood and other spine problem

• sleep apnea

• weight gain

• speech and language problems

Individuals with proportionate short stature (PSS) may have poorly developed organs and pregnancy complications, such as respiratory problems. Delivery will normally be by cesarean section.

Outlook

Most people with short stature will have a normal life expectancy, and 90 percent of children who are small for their age at 2 years will "catch up" by adulthood.

The 10 percent who do not catch up are likely to have a condition such as fetal alcohol, Prader-Willi, or Down syndrome.

A person with achondroplasia can also expect a normal lifespan.

However, some serious conditions that are linked to some cases of short stature can be fatal.

[cosworld-in]

Aloe Vera Peel Off Mask: The Ultimate Guide for Glowing Skin

Aloe vera has been celebrated for centuries due to its myriad health and beauty benefits. One of its most popular uses in contemporary skincare is the aloe vera peel-off mask. This natural treatment offers a plethora of benefits, making it a must-have in your beauty regimen. In this article, we will delve deep into the benefits, preparation methods, application techniques, and tips for using an aloe vera peel-off mask to achieve radiant skin.

Benefits of Aloe Vera Peel Off Mask

1. Deep Cleansing

Aloe vera peel-off masks are renowned for their ability to provide deep cleansing. The mask adheres to the skin, binding with dirt, dead skin cells, and other impurities. When peeled off, it removes these impurities, leaving the skin fresh and clean.

2. Hydration and Moisturization

Aloe vera is known for its exceptional hydrating properties. The gel contains compounds like mucopolysaccharides that help bind moisture to the skin. Using an aloe vera peel-off mask can ensure that your skin remains well-hydrated and moisturized, preventing dryness and flakiness.

3. Soothing and Healing

Aloe vera has potent anti-inflammatory and healing properties. It can soothe irritated skin, reduce redness, and accelerate the healing of minor cuts and sunburns. The peel-off mask helps in delivering these benefits directly to the skin, providing immediate relief.

4. Anti-Aging Benefits

Regular use of an aloe vera peel-off mask can help reduce the appearance of fine lines and wrinkles. The antioxidants in aloe vera combat free radicals, preventing premature aging and promoting youthful, supple skin.

5. Brightening and Even Skin Tone

Aloe vera contains aloin, a compound known for its depigmenting properties. It can help lighten dark spots, reduce pigmentation, and promote an even skin tone. The peel-off mask aids in delivering these benefits effectively, resulting in brighter, more radiant skin.

How to Prepare an Aloe Vera Peel Off Mask

Ingredients Needed

Fresh aloe vera gel (from an aloe vera leaf or store-bought pure aloe vera gel)

Unflavored gelatin or agar-agar powder

A few drops of essential oil (optional for fragrance)

A small bowl and a brush for application

Step-by-Step Preparation

Extract the Aloe Vera Gel: If using a fresh aloe vera leaf, cut it open and scoop out the gel. Ensure you have about 2 tablespoons of aloe vera gel.

Mix with Gelatin: In a small bowl, mix the aloe vera gel with 1 tablespoon of unflavored gelatin or agar-agar powder. Stir well to combine.

Heat the Mixture: Heat the mixture in a microwave or over a double boiler until the gelatin dissolves completely. Be careful not to overheat.

Add Essential Oil: If you prefer, add a few drops of your favorite essential oil to the mixture for added benefits and fragrance.

Let it Cool Slightly: Allow the mixture to cool slightly but not solidify. It should be warm and spreadable.

Application Techniques

1. Prepare Your Skin

Before applying the mask, ensure your face is clean and free of makeup. Use a gentle cleanser to remove any dirt and oil. Pat your face dry with a soft towel.

2. Apply the Mask

Using a brush, apply the warm aloe vera mixture evenly to your face, avoiding the delicate areas around your eyes and mouth. Apply a slightly thicker layer on areas with blackheads or impurities for better results.

3. Let it Dry

Allow the mask to dry completely. This usually takes about 20-30 minutes. As the mask dries, it will tighten on your skin.

4. Peel Off Gently

Once the mask is fully dry, start peeling it off gently from the edges. Be cautious not to pull too hard, especially if you have sensitive skin.

5. Rinse and Moisturize

After peeling off the mask, rinse your face with lukewarm water to remove any residue. Follow up with your favorite moisturizer to lock in the hydration.

Tips for Using Aloe Vera Peel Off Mask

1. Patch Test

If you are using aloe vera for the first time, it's essential to perform a patch test. Apply a small amount of the mask on your wrist or behind your ear and wait for 24 hours to check for any allergic reactions.

2. Frequency of Use

For best results, use the aloe vera peel-off mask 1-2 times a week. Overuse can lead to dryness or irritation.

3. Customize Your Mask

You can customize your aloe vera peel-off mask by adding other beneficial ingredients like honey, turmeric, or green tea extract. These can enhance the mask's benefits and address specific skin concerns.

4. Store Properly

If you have leftover mask mixture, store it in an airtight container in the refrigerator. Use it within a week to ensure its efficacy.

5. Stay Consistent

Consistency is key to seeing significant results. Make the aloe vera peel-off mask a regular part of your skincare routine to enjoy its full benefits.

Conclusion

An aloe vera peel-off mask is a powerful addition to any skincare routine, offering deep cleansing, hydration, soothing, anti-aging, and brightening benefits. With its natural ingredients and easy preparation, it is an accessible and effective treatment for achieving glowing, healthy skin.

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