#mikhail shapiro

[rrrauschen]

Nadezhda Kosheverova & Mikhail Shapiro, {1947} Золушка (Cinderella)

[apod]

2024 December 13

M51: Tidal Streams and H-alpha Cliffs Image Credit & Copyright: The Deep Sky Collective - Tim Schaeffer, Carl Björk, Steeve Body, Fabian Neyer, Aki Jain, Ryan Wierckx, Paul Kent, Brian Valente, Antoine & Dalia Grelin, Nicolas Puig, Stephen Guberski, Mike Hamende, Julian Shapiro, John Dziuba, Mikhail Vasilev, Bogdan Borz, Adrien Keijzer

Explanation: An intriguing pair of interacting galaxies, M51 is the 51st entry in Charles Messier's famous catalog. Perhaps the original spiral nebula, the large galaxy with whirlpool-like spiral structure seen nearly face-on is also cataloged as NGC 5194. Its spiral arms and dust lanes sweep in front of its smaller companion galaxy, NGC 5195. Some 31 million light-years distant, within the boundaries of the well-trained constellation Canes Venatici, M51 looks faint and fuzzy to the eye in direct telescopic views. But this remarkably deep image shows off stunning details of the galaxy pair's striking colors and fainter tidal streams. The image includes extensive narrowband data to highlight a vast reddish cloud of ionized hydrogen gas recently discovered in the M51 system and known to some as the H-alpha cliffs. Foreground dust clouds in the Milky Way and distant background galaxies are captured in the wide-field view. A continuing collaboration of astro-imagers using telescopes on planet Earth assembled over 3 weeks of exposure time to create this evolving portrait of M51.

∞ Source: apod.nasa.gov/apod/ap241213.html

[sometimesigif]

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[uzaydanhaberler]

M51: Gelgit Akıntıları ve H-alfa Falezleri

Günün Astronomi Görseli 13 Aralık 2024 Görsel & Telif: The Deep Sky Collective – Tim Schaeffer, Carl Björk, Steeve Body, Fabian Neyer, Aki Jain, Ryan Wierckx, Paul Kent, Brian Valente, Antoine & Dalia Grelin, Nicolas Puig, Stephen Guberski, Mike Hamende, Julian Shapiro, John Dziuba, Mikhail Vasilev, Bogdan Borz, Adrien Keijzer Birbiriyle etkileşim halinde olan ilgi çekici galaksi çifti M51,…

[jcmarchi]

Ultrasound Enables Less-Invasive Brain–Machine Interfaces - Technology Org

New Post has been published on https://thedigitalinsider.com/ultrasound-enables-less-invasive-brain-machine-interfaces-technology-org/

Ultrasound Enables Less-Invasive Brain–Machine Interfaces - Technology Org

Brain–machine interfaces (BMIs) can read brain activity and translate that activity to control an electronic device like a prosthetic arm or computer cursor. They promise to enable people with paralysis to move prosthetic devices with their thoughts.

Ultrasound is used to image two-dimensional sheets of the brain, which can then be stacked together to create a 3-D image. Image Credit: Courtesy of W. Griggs

Many BMIs require invasive surgeries to implant electrodes into the brain in order to read neural activity. However, in 2021, Caltech researchers developed a way to read brain activity using functional ultrasound (fUS), a much less invasive technique.

Now, a new study is a proof-of-concept that fUS technology can be the basis for an “online” BMI—one that reads brain activity, deciphers its meaning with decoders programmed with machine learning, and consequently controls a computer that can accurately predict movement with very minimal delay time.

The study was conducted in the Caltech laboratories of Richard Andersen, James G. Boswell Professor of Neuroscience and director and leadership chair of the T&C Chen Brain–Machine Interface Center; and Mikhail Shapiro, Max Delbrück Professor of Chemical Engineering and Medical Engineering and Howard Hughes Medical Institute Investigator.

The work was a collaboration with the laboratory of Mickael Tanter, director of physics for medicine at INSERM in Paris, France.

[embedded content]

“Functional ultrasound is a completely new modality to add to the toolbox of brain–machine interfaces that can assist people with paralysis,” says Andersen. “It offers attractive options of being less invasive than brain implants and does not require constant recalibration. This technology was developed as a collaborative effort that one lab could not accomplish alone.”

“In general, all tools for measuring brain activity have benefits and drawbacks,” says Sumner Norman, former senior postdoctoral scholar research associate at Caltech and a co-first author.

“While electrodes can very precisely measure the activity of single neurons, they require implantation into the brain itself and are difficult to scale to more than a few small brain regions. Non-invasive techniques also come with tradeoffs. Functional magnetic resonance imaging [fMRI] provides whole-brain access but is restricted by limited sensitivity and resolution. Portable methods, like electroencephalography [EEG], are hampered by poor signal quality and an inability to localize deep brain function.”

Ultrasound imaging works by emitting pulses of high-frequency sound and measuring how those sound vibrations echo throughout a substance, such as various human body tissues.

Sound waves travel at different speeds through these tissue types and reflect at the boundaries between them. This technique is commonly used to take images of a fetus in utero, and for other diagnostic imaging.

A brain 3D model – illustrative photo. Image credit: Lisa Yount via Unsplash, free license

Because the skull itself is not permeable to sound waves, ultrasound for brain imaging requires a transparent “window” to be installed into the skull. “Importantly, ultrasound technology does not need to be implanted into the brain itself,” says Whitney Griggs (PhD ’23), a co-first author on the study.

“This significantly reduces the chance for infection and leaves the brain tissue and its protective dura perfectly intact.”

“As neurons’ activity changes, so does their use of metabolic resources like oxygen,” says Norman. “Those resources are resupplied through the blood stream, which is the key to functional ultrasound.”

In this study, the researchers used ultrasound to measure changes in blood flow to specific brain regions. In the same way that the sound of an ambulance siren changes in pitch as it moves closer and then farther away from you, red blood cells will increase the pitch of the reflected ultrasound waves as they approach the source and decrease the pitch as they flow away.

Measuring this Doppler-effect phenomenon allowed the researchers to record tiny changes in the brain’s blood flow down to spatial regions just 100 micrometers wide, about the width of a human hair. This enabled them to measure the activity of tiny neural populations simultaneously, some as small as just 60 neurons, widely throughout the brain.

The researchers used functional ultrasound to measure brain activity from the posterior parietal cortex (PPC) of non-human primates. This region governs the planning of movements and contributes to their execution. The Andersen lab has studied the region for decades using other techniques.

The animals were taught two tasks, requiring them to either plan to move their hand to direct a cursor on a screen, or plan to move their eyes to look at a specific part of the screen. They only needed to think about performing the task, not actually move their eyes or hands, as the BMI read the planning activity in their PPC.

“I remember how impressive it was when this kind of predictive decoding worked with electrodes two decades ago, and it’s amazing now to see it work with a much less invasive method like ultrasound,” says Shapiro.

The ultrasound data was sent in real-time to a decoder (previously trained to decode the meaning of that data using machine learning), and subsequently generated control signals to move a cursor to where the animal intended it to go. The BMI successfully did this to eight radial targets with mean errors of less than 40 degrees.

“Significantly, the technique does not require the BMI to be recalibrated each day, unlike other BMIs,” says Griggs. “As an analogy, imagine needing to recalibrate your computer mouse for up to 15 minutes daily before use.”

Next, the team plans to study how BMIs based on ultrasound technology perform in humans, and to develop the fUS technology further to enable three-dimensional imaging for improved accuracy.

Written by Lori Dajose

Source: Caltech

You can offer your link to a page which is relevant to the topic of this post.

[sasquapossum]

This looks like amazing news.

Hey @afeelgoodblog what do you think?

[infosnack]

STAT: A yogurt drink instead of a colonoscopy? Study uses engineered bacteria to detect cancer

STAT+: A yogurt drink instead of a colonoscopy? Study uses engineered bacteria to detect cancer https://www.statnews.com/2023/08/10/colon-cancer-test-engineered-bacteria/?utm_campaign=rss Dan Worthley, a gastroenterologist and cancer scientist at Colonoscopy Clinic in Brisbane, Australia, does thousands of colonoscopies a year, seeking and destroying precancerous polyps. It’s a practically surefire way to prevent colorectal cancer, but an unpleasant experience for patients. The future, Worthley hopes, will be much less onerous — and he’s developing a technology that, if it works one day, might make the experience more of a piece of cake. Or, rather, a cup of yogurt — containing engineered bacteria that can detect and deliver a treatment for colorectal polyps or cancer. Worthley and colleagues at the University of California, San Diego, and the University of Adelaide published results in Science on Thursday that show they are one step closer to that far-off dream. In their paper, the researchers show a proof-of-concept engineered bacterium that can detect cancer DNA in the guts of mice and react to it by turning on certain cellular circuitry. “I think it’s really cool. It introduces a new concept for how you can use cells as a sensor for something happening inside other cells,” said Mikhail Shapiro, a chemical and medical engineer at the California Institute of Technology who did not work on the study. “That can flip a switch inside those cells. In this case, it’s used for diagnostic output, but in principle it could be used for other things.” Continue to STAT+ to read the full story… via STAT Health - Science and medicine news https://www.statnews.com/category/health/ August 10, 2023 at 02:00PM

[dailykino]

Cinderella | Золушка (1947) dir. Nadezhda Kosheverova, Mikhail Shapiro

[solonocturne]

On the set of Cinderella, 1947, dir. Nadezhda Kosheverova and Mikhail Shapiro

[ariel-seagull-wings]

@mademoiselle-princesse @princesssarisa @superkingofpriderock @sunlit-music

Zolushka | Золушка (Nadezhda Kosheverova, Mikhail Shapiro, 1947)

[warningsine]

for the film ask: 1, 10, 11, 15, 21, 71

1. Favorite action film?

"A Touch of Zen" by King Hu

"New Dragon Gate Inn" by Raymond Lee

"Hero" & "House of Flying Daggers" by Yimou Zhang

"Crouching Tiger, Hidden Dragon" by Ang Lee

10. Favorite animated movie?

Oh, too many.

"Persepolis" by Vincent Paronnaud and Marjane Satrapi

"The Triplets of Belleville" by Sylvain Chomet

"Waltz with Bashir" by Ari Folman

"Millennium Actress" and "Perfect Blue" by Satoshi Kon

"The Red Turtle" by Michaël Dudok de Wit

"Josep" by Aurel

"Thumbelina" by Lotte Reiniger

"Chico & Rita" by Tono Errando, Fernando Trueba and Javier Mariscal

"The Secret of Kells" by Tomm Moore

"The Swallows of Kabul" by Zabou Breitman and Eléa Gobé Mévellec

"Tale of Tales" by Yuri Norstein

"Belladonna of Sadness" by Eiichi Yamamoto

"Metropolis" by Rintaro

"Miss Hokusai" by Hinako Sugiura

11. Favorite musical?

Oh, boy. Musicals give me life so the list is gonna be long.

Obviously, you'll often hear me singing the classics ('cause I adore them wholeheartedly):

"Fiddler on the Roof"

"My Fair Lady"

"Victor/Victoria"

"Cabaret"

"All About Jazz"

"West Side Story"

"Oliver!"

"A Star Is Born"

"Singin’ in the Rain"

"Young Girls of Rochefort"

"Umbrellas of Cherbourg"

but I also love:

"8 women" by François Ozon

"Fado: The Story of a Singer" by Perdigão Queiroga

"Victimas del Pecado" by Emilio Fernandez

"Alla en el Rancho Grande" by Fernando de Fuentes

"Tangos, the Exile of Gardel" by Fernando Solanas

"Blood Wedding" by Carlos Saura

"El Gran Casino" by Luis Buñuel

"Princess Raccoon" by Seijun Suzuki

"Le Million" by René Clair

"Sholay" by Ramesh Sippy

"Perhaps Love" by Peter Chan

"Orfeu" by Carlos Diegues

"Cinderella" by Nadezhda Kosheverova & Mikhail Shapiro

"The Congress Dances" by Erik Charell

"Fatmah" by Umm Kulthum

"The Happiness of the Katakuris" by Takashi Miike

"Black Orpheus" by Marcel Camus

"Where Do We Go Now?" by Nadine Labaki

"Zouzou" by Marc Allégret

"Ay Carmela!" by Carlos Saura

"Singing Lovebirds" by Masahiro Makino

"French Cancan" by Jean Renoir

"Days and Nights" by Henry Barakat

"Window Shopping" by Chantal Akerman

"No One Knows About Persian Cats" by Bahman Ghobadi

"A Good Lad" by Boris Barnet

"Mother India" by Mehboob Khan

"The Beloved" by Christophe Honoré

"Opera Jawa" by Garin Nugroho

"Same Old Song" by Alain Resnais

"Karmen Gei" by Joseph Gaï Ramaka

"La France" by Serge Bozon

"Destiny" by Youssef Chahine

"Hipsters by Valery Todorovsky

"Las Cosas del Querer" by Jaime Chávarri

"My voice" by Flora Gomes

"Black Cat, White Cat" by Emir Kusturica

15. Favorite chick flick?

I have beef with the term "chick flick," but "The Devil Wears Prada" will do, I guess. Also, "Breakfast at Tiffany's" and "Mamma Mia."

(Does "Thelma and Louise" even count as a chick flick? If yes, that is my favorite one.)

21. Favorite kids movie?

"Inside Out" by Pete Docter 

71. A move that made you ache for love.

"In the mood for love" by Wong Kar-Wai

"Brief Encounter" by David Lean

among others.

[softcallofdutyimagines]

Not Smokey, but here's a few Makarov replacement cast options. I did give a few of these to Smokey, so you might recognize the names if you haven't seen media with them.

Yuriy Borisov

Serafim Ionov in the movie T-34 (he's the first guy that speaks in this clip)

Mikhail Kalashnikov in the movie AK-47: Kalashnikov (it's the trailer for the movie, he'll introduce himself)

Interview (English auto-translate exists but are horrendous)

Pavel Priluchnyy

My personal favorite recasting of Makarov but only because I like the Netflix show Silver Spoon/Mazhor that he's in

Mikhail Devyatayev in the movie V2. Escape From Hell (he's the pilot. Don't trust English auto-translation here)

Lie to Me the Truth Movie (no translation option)

Interview (I don't think I need to say more about the auto-generated English)

Zack Sayenko

Alexander from Into the Silent Sea short film (22 minutes ENG subs, 4 minute segment in case you're short on time. Roman Varshavsky is also in here as Kaminin)

Vlad Lukov/Busboy from NCIS: LA

Never Say Nyet promo/discussion (can't find a regular interview)

Oleg Mirochnikov

Metro 2033 Artyom's diary entries (No English subs)

A Warsaw Melody Play interview (actually pretty fascinating)

Honorable Mentions:

Stitch and Adler's Russian dub (whom I can't find the names to)

None of them can replace Roman Varshavsky, of course, but maybe you'll find one of them interesting or hear Makarov's voice in a different style. And rid the Ben Shapiro.

Hmmmm, time to dive into this absolute FEAST 😩🙏🏻

Ok, first guy:

This man passed the ancestry.com test for 100% slav, so I do like that lmao. I think with the black hair and some stubble he'd actually be pretty damn close for Makarov. His voice is also not too bad, I feel like it's a little too sexy for Makarov 😅😅😅 It's moderately deep and strong, I feel like Makarov needs a hissy type voice

Pavel:

Honestly, I also like this choice a lot 👀👀👌🏻 His voice is actually really, good and close to what I imagined. He has the ssss at the end of his words but he has just the right amount of deep and sexy that it still works 😳👀 His face is just throwing me off a little 😅 He's got this ultra baby face, and it's just not working. Maybe some stubble would help cover it up tho, so I wouldn't count him out

Zack:

Oof, not feeling this one 😪 He sounds and looks like a really big kid, and unfortunately it's just not working 😭 He is cute tho 💖

Oleg:

Ok, this man just has a perfect villain voice in general 😩 Unfortunately it is way too deep for our 5'9 king 😭😭 Low key feel like he would make a good stitch 👀

Honorable mention:

Same as above tbh, but not as deep

Overall, I really actually kind of like the idea of him having an "annoying" voice, like it doesn't have to be deep and silky you know? I'm just looking for an accent and a little intimidating edge to the voice.

Honestly, I can't really choose between the first two which I like best, but maybe I'd have to go with Pavel 😩🙏🏻🙏🏻 Thank you for your service Broccoli 🙏🏻

[sovietpostcards]

Faina Ranevskaya as stepmother in Cinderella, Soviet film directed by Nadezhda Kosheverova and Mikhail Shapiro (1947)

[cineindependientemx-blog]

Optic Chiasm parte 3

Nombre del ciclo;

¨Optic Chiasm parte 3¨

Títulos;

Chi-Raq (2015) 127 min Director: Spike Lee Country: USA Language: English http://www.imdb.com/title/tt4594834/

The Stunt Man (1980) 131 min Director: Richard Rush Country: USA Language: English http://www.imdb.com/title/tt0081568/

Modisto de Señoras (1969) Fray Don Juan (1970) Espérame en Siberia, vida mía (1971) 85 min 87 min 90 min Director: René Cardona Jr. Country: Mexico Language: Spanish http://www.imdb.com/title/tt0244660/ http://www.imdb.com/title/tt0244517/ http://www.imdb.com/title/tt0065705/

Zolushka (1947) aka ´Cinderella´ (English title) 80 min Directors: Nadezhda Kosheverova, Mikhail Shapiro Country: Soviet Union Language: Russian http://www.imdb.com/title/tt0168269/

Para cerrar, diálogo después de ver;

The Parson's Widow (1920) aka ´Prästänkan´ (original title) La Passion de Jeanne d'Arc (1928) Vampyr (1932) Day of Wrath (1943) aka ´Vredens dag´ (original title) Ordet (1955) 71 min 97 min 75 min 110 min 126 min Director: Carl Theodor Dreyer Country: Sweden | Denmark | France | Germany Language: Danish | German http://www.imdb.com/title/tt0011607/ http://www.imdb.com/title/tt0019254/ http://www.imdb.com/title/tt0023649/ http://www.imdb.com/title/tt0036506/ http://www.imdb.com/title/tt0048452/

  http://cineindependientemx.blogspot.mx/

[natashaivanov]

Natasha’s phone was pressed close to her ear, her full lips twisted into a hard line. “No -- no. Mikhail’s interview was supposed to be pushed until Friday, not Thursday. Call the station and tell them he’ll be in a meeting with Mayor Shapiro, and if they try to tell you they can’t do it, remind them that they’re the ones who begged him to come in.” The person on the other line started chattering away, causing the blonde to scowl. “I don’t care if they’ve already booked him for Thursday. He’s on Friday, or not at all.”

With that, she hung up with a sharp click of the end call button. “I swear, I have to do everything myself,” She grumbled, pushing out of the revolving door of her office, only to knock shoulders with someone on the way out. “Oh, really?” Natasha gasped, her briefcase spilling open on the concrete.