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CAS 14680-51-4
English name Metonitazene
CAS No. 14680-51-4
Density 1.2±0.1 g/cm3
Boiling point 571.8±45.0 °C at 760 mmHg
Molecular formula C21H26N4O3
Molecular weight 382.456
Flash point 299.6±28.7°C
Exact mass 382.200500
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BBC: Super-strength opioids spreading across Europe and North America – UN
COGwriter
The BBC reported the following:
Super-strength opioids spreading across Europe and North America – UN
26 June 2024
The use of nitazenes, a group of drugs which can be more potent than fentanyl, is spreading across Europe and North America, the UN drug agency has warned.
The synthetic opioids have been detected in the UK, US, Slovenia, Estonia, Latvia, Belgium and Canada, the UN Office on Drugs and Crime (UNODC) wrote in its latest World Drug Report.
There has also been an increase in the number of deadly overdoses connected with nitazenes.
The super-strength drugs, of which there are several types, are significantly more potent than heroin. Their emergence has prompted urgent warnings from health agencies around the world.
It follows a ban on poppy cultivation in Afghanistan, which saw opium production drop by 95% in 2022.
It is too early to know what long-term effects this may have on factors such as heroin purity, the UNODC report says, but it will likely lead to heroin users switching to other opioids, which may “lead to an increase in overdoses”. …
Fentanyl, another synthetic opioid, is 50 times more powerful than heroin. Its highly-publicised epidemic in the US contributed to 100,000 deaths in 2022, according to the Center for Disease Control and Prevention.
The UNODC’s report states that “illicitly manufactured fentanyls” are still behind “unprecedented number of overdose deaths,” the numbers “may be tapering off.”
Global drug use increased by 20% in the past decade to 292 million users in 2022, the report said.
Cannabis remains the most widely used with 228 million users worldwide. It is followed by:
Opioids – 60 millionAmphetamines – 30 millionCocaine – 23 millionEcstasy – 20 million
https://www.bbc.com/news/articles/crgge1ez0r2o
National Institute on Drug Abuse website states:
Nitazenes are a class of lab-made (synthetic) opioids that may be as powerful or more powerful than fentanyl.4 They were developed in research labs in the 1950s as potential pain relievers but never marketed. Nitazenes are most often sold as a white powder or tablets. People may not be aware that they have taken nitazenes, as they may be added to other substances, including fentanyl, heroin, and benzodiazepines.5
Nitazenes began to re-emerge in the drug supply in 2019, after the U.S. Drug Enforcement Administration banned fentanyl-related substances.6,7 Researchers and authorities are monitoring nitazenes, including isotonitazene, protonitazene, etonitazene, N-piperidinyl etonitazene, and metonitazene. Many nitazenes are listed as Schedule 1 drugs under the Controlled Substances Act.
Like all opioids, nitazenes can slow breathing, blood pressure, and heart rate to dangerously low levels, potentially contributing to overdose. https://nida.nih.gov/research-topics/emerging-drug-trends#nitazenes
Back in 1976, the old Worldwide Church of God published the following:
Psychoactive Drugs
Technically speaking, a drug is any substance (other than food) that by its chemical nature affects the structure or function of a living organism.
Doctors usually refer to a drug in terms of its ability to treat physical and mental diseases. They stress the therapeutic value. But many laymen now focus on the negative connotations of the word. For them, “drug” has become a four-letter word of the worst kind, an epithet, an obscenity. When used in conversation it provokes strong emotional reactions. It’s a good word to start an argument with, or even a fight.
Medicine and Menace
You encounter a lot of this when discussing drugs. They can relieve pain, prevent infection and save lives. That’s good! But they can also destroy bodily tissue, impair healthy bodily metabolism, enslave by addiction and ultimately kill. That’s bad!
The drug problem would be greatly simplified if drugs were not ambivalent, if they were very selective in their effects. If only drug X eased pain, but was not addicting, if only drug Y helped people relax but didn’t adversely affect the brain or the liver.
But drugs don’t work that way. Rather, their effects are varied and often ambivalent — they have the potential to simultaneously hurt or harm, depending on a number of variables. Because any drug can play both the role of medicine or health menace, any description of its effects is bound to sound like a “that’s-good, that’s-bad” routine.
Morphine presents a good example of a “that’s-good, that’s — bad” story. It came into widespread use as a pain-killer during the American Civil War (1861-65). So effective was it as an analgesic for wounds and amputations that physicians sometimes referred to it as “G.O.M.” — “God’s own medicine.”
That’s good!
But in time morphine was found to be addicting — prolonged use followed by abstinence led to agonizing withdrawal symptoms. “God’s own medicine” turned out to be “the Devil’s own misery.” Hundreds, if not thousands (accurate statistics are hard to come by), of war veterans inadvertently became drug addicts.
That’s bad!
But that’s the nature of opiates. And it illustrates a fundamental principle of pharmacology: any drug can be dangerous depending on the dosage, the duration of use, its purity and many other factors. No drug is completely “safe.”
Recognizing this, the Federal government under the Controlled Substances Act regulates drugs according to their potential for abuse. The drugs are listed in five schedules in descending order of proven abuse potential and current medical usage.
Schedule I lists drugs deemed to have great abuse potential and no legitimate medical use. The score or so drugs on this list include heroin, LSD, mescaline, psilocybin and marijuana.
Schedule II lists drugs with great abuse potential that have legitimate medical uses. Drugs in this list can come under production quotas, and telephone and refillable prescriptions are prohibited. The psychoactive drugs listed here include the opiates such as morphine and synthetic opiates such as methadone and Demeral, certain barbiturates of the short-acting type, methaqualone and amphetamines. Altogether over 1300 drug preparations are listed!
Schedules III, IV and V list drugs with correspondingly less proven abuse potential. The widely used tranquilizers Librium and Valium are in Schedule IV — a classification the manufacturers have protested. Altogether over 3600 drug preparations are covered by these three schedules.
The list is not static. On the basis of new evidence and accumulated experience, drugs are often being added to the list. And drugs already listed are sometimes moved to higher schedules, indicating greater proven abuse potential.
The dual nature of drugs guarantees that the debate over their benefits versus hazards will continue for some time. (Graunke DP. The Dilemma of Drugs. Worldwide Church of God, 1976)
Since that came out in 1976, the opioid and drug crisis has worsened.
The reality is that many have physical and spiritual pain and they reach out to drugs for relief. This tends to be addictive.
The Continuing Church of God (CCOG) put out the following video on our Bible News Prophecy YouTube channel:
youtube
13:19
Opioid Crisis
Since 1997, over 700,000 Americans have died related to opioids. What are opioids? What does the National Institute on Drug Abuse teach about them? Why do people use them? Are they effective? Can they be addictive when medically-prescribed? Does the UK have a problem with opioids? Did Great Britain force China to accept opioids in the 19th century? Has pharmaceutical greed been a factor in the opioid crisis? What is the dilemma of drugs? Is switching to non-opioid substances like marijuana the answer? Does the Bible provide insights related to mind altering substances? Dr. Thiel addresses these issues and more. A written article of related interest is available titled “Opioid Crisis Leaves 700,000 Americans Dead.”
Here is a link to the sermonette video: Opioid Crisis.
While the USA is fighting the opioid epidemic, it has also been in the process of increasing its marijuana epidemic, which more and more US states are encouraging.
The Bible teaches:
18 And do not be drunk with wine, in which is dissipation; but be filled with the Spirit (Ephesians 5:18)
21 For the drunkard and the glutton will come to poverty (Proverbs 23:21)
Notice something the Apostle Paul was inspired to write:
19 Or do you not know that your body is the temple of the Holy Spirit who is in you, whom you have from God, and you are not your own? 20 For you were bought at a price; therefore glorify God in your body and in your spirit, which are God’s. (1 Corinthians 6:19-20)
Getting stoned with marijuana or opioids is harmful to the body and is not glorifying God.
Mind altering drugs are not the answer.
Truly repenting and turning to the true Jesus and the coming Kingdom of God are.
As far as physical pain goes, let me close by saying that frequently, the cause is something in someone’s diet. Now, while not all are bothered by substances such as caffeine and bovine dairy, some are, and that is something that the medical field rarely diagnoses. There is no money for the pharmaceutical companies when the cause of discomfort is avoiding some substance.
Anyway, the drug situation in the USA is weakening the nation, and it shows no signs of truly changing that for the better.
Pray for God’s kingdom to come.
Related Items:
The Ten Commandments: The Decalogue, Christianity, and the Beast This is a free draft/unedited pdf book explaining the what the Ten Commandments are, where they came from, how early professors of Christ viewed them, and how various ones, including the Beast of Revelation, will oppose them. A related sermon is titled: The Ten Commandments and the Beast of Revelation.
Marijuana: Should a Christian Get High? There is increasing acceptance of the use of marijuana. How should Christians view this? Here is a related video titled How Should a Christian View Marijuana? Alcohol: Blessing or Curse? This is an article from the old Good News magazine that attempts to answer this question.
Binge Drinking, Health, and the Bible Many college students and others overindulge in alcohol. Are there health risks? What does the Bible teach? A related video is also available: Binge Drinking and the Bible.
How to Overcome Depression and Discouragement This is an article by Paul Krautmann & John Siston. The MYSTERY of GOD’s PLAN: Why Did God Create Anything? Why Did God Make You? This free online book helps answers some of the biggest questions that human have, including the biblical meaning of life. Here is a link to three related sermons: Mysteries of God’s Plan, Mysteries of Truth, Sin, Rest, Suffering, and God’s Plan, Mystery of Race, and The Mystery of YOU. Here is a link to two videos in Spanish: El Misterio del Plan de Dios and El Misterio de Satanás, el Misterio de la Verdad, el Misterio del Reposo.
Should Christians Smoke (or Chew) Tobacco or Marijuana? Is smoking a sin? What does the Bible teach? What have COG leaders written? Can smokers change? What about marijuana? Here is a link to a related video: Should You Smoke? Would You Like Help to Quit?
Real Conversion Many think that they are converted Christians. But are they? Would you like to know more about conversion?
False Conversion! Have you really been converted? Herbert W. Armstrong wrote an article on this important subject–but more scriptures have been added to it. How can you tell false conversion? A related video is also available: False Conversion.
Is God Calling You? This booklet discusses topics including calling, election, and selection. If God is calling you, how will you respond? Here is a link to a related sermon: Could God be Calling You? Christian Repentance Do you know what repentance is? Is it really necessary for salvation? A related sermon is also available titled: Real Christian Repentance.
Just What Do You Mean — Repentance? Do you know what repentance is? Have you truly repented? Repented of what? Herbert W. Armstrong wrote this as a booklet on this important subject.
The Gospel of the Kingdom of God This free online pdf booklet has answers many questions people have about the Gospel of the Kingdom of God and explains why it is the solution to the issues the world is facing. Here are links to three related sermons: The World’s False Gospel, The Gospel of the Kingdom: From the New and Old Testaments, and The Kingdom of God is the Solution.
USA in Prophecy: The Strongest Fortresses Can you point to scriptures, like Daniel 11:39, that point to the USA in the 21st century? This article does. A related sermon is titled: Do these 7 prophesies point to the end of the USA?
Canada in Prophecy: What Does Bible Prophecy, Catholic Prophecy, and other Predictions Suggest About the Future of Canada? There are prophecies that suggest involvement with Canada. And many are not positive about its future.
Who is the King of the West? Why is there no Final End-Time King of the West in Bible Prophecy? Is the United States the King of the West? Here is a version in the Spanish language: ¿Quién es el Rey del Occidente? ¿Por qué no hay un Rey del Occidente en la profecía del tiempo del fin?
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UK Implements Comprehensive Strategy for Type A Drugs
New Class A Designation for Synthetic Opioids
The UK government is set to ban 15 new synthetic opioids, categorizing them as Class A drugs under the Misuse of Drugs Act 1971. This move follows advice from the Advisory Council on the Misuse of Drugs (ACMD), aiming to safeguard communities and prevent overdoses. Stiff Penalties for Possession and Supply Possession of a Class A drug carries a sentence of up to seven years imprisonment, an unlimited fine, or both. For supply offenses, the penalty can escalate to life imprisonment, an unlimited fine, or both. The severity of these penalties reflects the government's commitment to tackling the illicit drug trade.
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Many of the newly banned substances exhibit effects similar to heroin and fentanyl, increasing the risk of accidental overdose. While there's no conclusive evidence of their prevalence in the UK, the government is taking proactive measures due to reported deaths linked to these drugs in other countries. Minister's Call to Action Crime and Policing Minister Chris Philp emphasized the potential devastation caused by these dangerous substances. The strategy involves a dual approach — combatting the illicit drug supply chain and establishing an effective treatment system to break the cycle of addiction and crime.
Newly Banned Synthetic Opioids
Parliament's Approval Pending The proposed ban includes synthetic opioids such as metonitazene, protonitazene, and others, all subject to parliamentary approval. This regulatory step is part of the ongoing government efforts to address the supply of harmful drugs and reduce criminal activities.
Synthetic Opioids Added to Class A
Drug Name metonitazene protonitazene isotonitazene butonitazene flunitazene metodesnitazene (metazene) etodesnitazene (etazene) N-pyrrolidino-etonitazene (etonitazepyne) N-piperidinyl-etonitazene (etonitazepipne) N-pyrrolidino protonitazene ethyleneoxynitazene N-desethyl protonitazene N-desethylisotonitazene N-desethyl-etonitazene brorphine Government’s Recent Achievements This ban is a continuation of the government's broader anti-drug strategy. Since April 2022, over 1,700 county lines have been closed, and more than 4,900 organized crime groups disrupted. The government has also increased treatment places by 12,000 compared to March 2020.
Expanding the Ban to Other Harmful Substances
Additional Controlled Substances In addition to the synthetic opioids, the ban extends to other harmful substances. Cumyl-PeGaClone, a synthetic cannabinoid receptor agonist, and three stimulants with effects similar to ketamine — diphenidine, ephenidine, and methoxyphenidine — will be controlled as Class B drugs. Remimazolam, a short-acting benzodiazepine, will be classified as a Class C drug. Balancing Control with Legitimate Uses The government aims to strike a balance between control and legitimate medical use. By regulating these substances, it aims to curb potential complications, including seizures and liver failure, associated with their misuse. In conclusion, the UK government's decision to ban these 20 dangerous drugs reflects its commitment to public safety and addressing the evolving challenges posed by synthetic opioids and other harmful substances. The proposed measures underscore the need for a comprehensive strategy that combines stringent control measures with initiatives to support rehabilitation and break the cycle of addiction. Sources: THX News, Home Office, Advisory Council on the Misuse of Drugs, & The Rt Hon Chris Philp MP. Read the full article
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