#lacharme

[phoenix-dali-blog]

I Sister, Where Art Thou, Vol.2 Fashion bridal editorial shot in downtown LA, published on GMARO Magazine #fashioneditorial #dtla O Sister, Where Art Thou Vol.2 Photographer @dali.photographer Model @anyakolodinskaya @nastyamilicevic Designer @swanbridalsa MUAH @lacharmed Published on @gmaromagazine . . . . . . #Dali #fashionphotographer #LAphotographer #FashionAddict #fashionmodel #fashionweek #fashiondiaries #editorialfashion #theclassylifestyle #lovefashion #humanedge #fashionable #designerclothes #美人 #portraitsvisuals #portrait_society #portraitvision_ #globe_portraits #globe_people #nextonthepage #CreateToInspire #agencymodel #lamodels #canonphotography #downtown (at Los Angeles, California) https://www.instagram.com/p/CndIH7lv0lZ/?igshid=NGJjMDIxMWI=

[williamgunst]

Quatre conseils pour investir dans une place de parking

Quatre conseils pour investir dans une place de parking

Une place de parking à 4 000 euros, dans le 18e arrondissement de Paris. Il s’agit du premier achat d’Alexandre Lacharme, en 2013, alors qu’il avait 27 ans. “C’était mal fait et trop étroit pour qu’une voiture puisse s’y garer”, se souvient-il. Je l’ai donc loué pour une moto, à 45 euros par mois. 🇧🇷Investir dans des places de parking présente plusieurs avantages. Tout d’abord, le droit d’entrée,…

[frolickinggnomes]

Pixie LaCharm

New Year, New Challenge!

I’m trying out the Magical Bloodlines challenge by @anxiousmoodlet

You are the beginning, you are where it all begins. You take a bold step on to a path your family has never walked before, and begin a legacy that will echo through the Realm of Magic for the rest of time. Or maybe not. Who knows? It’s your legacy.

Mischievous and playful they call you. Many often wince at the mention of your name remembering the last encounter with your hand buzzer. They say laughter is the best medicine and you intend to live a very long time...

Traits: childish, hot headed, outgoing Aspiration: Spellcraft and Sorcery Magic school: Mischief

Rules

Become a spellcaster

Live in the secluded woods of Glimmerbrook

Max skills: Mischief, baking and dancing

Grow at least five perfect flower plants in your garden.

Earn the People Person lifestyle and Carefree reward trait

Complete the Insects collection

Acquire the Fairy familiar

Reach the Virtuoso spellcaster level

Have 5 children

[leahsfiction]

Katydid Song - Anonymous | 螽斯

katydid song we millions strong listen all my children we shake ourselves awake

katydid song we swarm along listen all my children we all form our lines

katydid song we bid you "so long" listen all my children and now we go to sleep

--

here's a performance in Mandarin (although the instrumentation, pronunciation, and melody are all new; iirc all of the original melodies for classical Chinese poetry have been lost. all we have now are the reconstructed rhymes and tone-patterns.)

this is a very old song collected in the Shijing (Book of Songs). have some slightly less old translations courtesy of Wikipedia, starting with a translation into Latin:

Lacharme, Confucii Chi-king, sive, Liber carminum, 1850.

Ode 5

Papiliones dicti Tchong-see, vos animorum magna concordia in eumdem locum convenitis; et quam florens ex vobis nascetur progenies!

Papilionum aus constrepit aer, non interrupta eist vestrorum series.

Papilio Tchong-see, tu cum tuis gragalibus una simul: ex nepotibus tuis gens magna exsurgit.

--

Jennings, The Shi king, the old poetry classic of the Chinese, 1891.

1.I.5. The Locusts

How do the locusts crowd— A fluttering throng! May thy descendants be Thus vast, thus strong!

How do the locusts' wings In motion sound! May thy descendants show, Like them, no bound!

How do the locusts all Together cluster! May thy descendants too In such wise muster!

--

Karlgren, "Bulletin no 16," The Museum of Far Eastern Antiquities, Stockholm Östasiatiska museet, 1944.

The wings of the locusts, they are multitudinous; it is (suitable:) right that your sons and grandsons should be numerous.

The wings of the locusts, they are in great numbers; it is right that your sons and grandsons should be in a continuous line.

The wings of the locusts, they are in crowds; it is right that your sons and grandsons should be (clustering:) in great swarms.

--

Owen, An Anthology of Chinese Literature, 1996.

Grasshoppers' wings are teeming, teeming; fit that your offspring be thus abounding.

Grasshoppers' wings, are swarming, swarming; fit that your offspring go on never-ending.

Grasshoppers' wings, are thronging, thronging; fit that your offspring be fruitful and grow rife.

[14kcharms-blog]

Launched my new website. If you guys can do me a favor and visit it I would greatly apprectiate it! www.LAcharms.com

[ourbeautyhouse]

This summer will never end! 💖💜 - - - - - #faceprimer: #undermakeupbbase by @inglotgreece #foundation: #beyondperfecting by @clinique #concealer: #fitme No. 20 by @maybelline & #NakedSkin fair neutral by @urbandecaycosmetics #Facepowder: #FreedomSystem 24 by @inglotgreece & for beking #drypowder by @kryolangreece #blush: #dandelion by @benefitcosmeticsgreece #eyeshadowbase: #primerpotion by @urbandecaycosmetics #eyeshadow: #naturaleyes by @toofaced & #pigment By @dustandcream #Mascara: #rollerlash by @benefitcosmeticsgreece #lashes: #lacharme

[alexandrelacharme]

BBQ post training sur les quais le top 👍 #bbq #post training #jiujitsu #paris #barbecue #instalife #germany #lacharme #graciebarraparis (at Pont Alexandre III)

[maximetemple]

I had the chance to direct a short movie for the play "Maqo" staged By Alice Lacharme, Here Some preprod Stuff

[xlevelpr]

ENTRÓ EN FUNCIONAMIENTO VILLABICI, EL SISTEMA PÚBLICO DE BICICLETAS DE VILLAVICENCIO

ENTRÓ EN FUNCIONAMIENTO VILLABICI, EL SISTEMA PÚBLICO DE BICICLETAS DE VILLAVICENCIO

Con 120 bicicletas y 7 estaciones, entró en funcionamiento el sistema público de bicicletas VillaBici, que estará a cargo de la empresa pública Alborada. “Es un paso más para promover en los ciudadanos el transporte sostenible, que es amigable con el medio ambiente, con la salud de los ciudadanos y que mejora la calidad de vida de todos”, dijo Alejandro Lacharme, gerente de Alborada. En total,…

[pharmaphorumuk]

How will NICE fare in a post-Brexit world?

NICE has a global reputation as a pioneering HTA – but is that influence at risk now that the UK has left the EU? Experts from ICON give us their views on the past, present and future of NICE’s standing on the world stage.

This article appears in our digital magazine, Deep Dive: Market Access 2021. Read below for a preview:

One of the earliest and most pronounced impacts of the UK’s vote to leave the European Union was the loss of the European Medicines Agency (EMA). Long headquartered in London, the EU drug regulator is now severed from the country both physically and systematically, with its base now in Amsterdam and the UK now assessing drugs through its own regulatory agency, MHRA.

This leaves the UK’s drug pricing watchdog, the National Institute for Health and Care Excellence (NICE), in an uncertain position. Once a leading voice in health technology assessment (HTA) in both Europe and the wider world, the body now finds itself unable to work as closely with the EMA – and by extension countries in the EU – as it did in the past.

Emmanuel Lacharme, previously a technical analyst at NICE and now senior consultant, global health economics and outcomes research at ICON, is confident that NICE’s existing reputation will help it maintain its global standing in the immediate future – but notes that there is still a risk the body will become “isolated” as a result of Brexit, particularly as companies are no longer able to rely on the EU’s centralised approval system for the UK.

“There will be uncertain times, but also new opportunities,” he says.

“I believe that NICE will try to do as much as possible to support our industry, by offering early engagements and a streamlined MHRA and NICE parallel approval process. Practically though, there are risks of additional processes and requirements (and expense) for pharmaceutical companies. This additional effort could lead to poorer patient access.

“It is also possible that companies may prefer to enter the EU market through the EMA process and avoid additional processes involving the MHRA and NICE. It’s important to remember that the UK market represents only 2.5% of global pharmaceutical sales, while the entire European market represents more than 20%.”

Caroline Delaitre-Bonnin, senior principal, global health economics and outcomes research at ICON, notes that this could lead to companies no longer seeing the UK as an early launch market.

“The UK has traditionally been an early launch market for pharmaceuticals partly because UK prices are often used as a reference price for other countries, and also because NICE assessments are held in high esteem. Brexit could change this.

“It’s difficult to say whether NICE will maintain the same leadership position in Europe that it has in past years.”

But uncertainty goes both ways, and at the moment it is also too early to say that NICE won’t be able to maintain – or perhaps even strengthen – its influence under the right circumstances.

Lacharme points out that NICE does, at the very least, have a very strong foundation to build upon.

“NICE has always been a great reference in HTA for cost-effectiveness analysis (CEA) and cost-utility analysis (CUA) of new medicines,” he says. “For example, its 2013 guide to the methods of technology appraisal is still a valid reference to understand the key principles of cost effectiveness within an HTA context, and NICE decision support unit documents are a useful resource for any health economist needing technical or educational support.

“While NICE’s first target is the UK NHS, this information can also be useful for other EU health services – especially when a country has not developed its own guidance – and even the US, where evaluation from the institute for clinical and economic review becoming more important, using NICE principles of CEA/CUA.”

With NICE having had a significant influence on the development of other HTA authorities’ methodologies over the last 20 years, Manpreet Sidhu – ICON’s executive principal, global health economics and outcomes research – says the agency’s influence has a good chance of remaining robust over the coming years.

“NICE is still considered to offer a transparent and clear methodological framework for regulators and companies, and so whilst the intricacies of working in a post-Brexit world are ironed out it would seem unlikely that pharma companies/regulators would move away from continuing to engage with NICE.”

Sidhu says it will be important for NICE to continue to lead discussions on methodological perspectives within HTA bodies if it wants to maintain its reputation.

“Being a flagship HTA, where other HTA bodies look to NICE methodologies as a signpost, has been great for the agency,” she says.

“To continue on that trajectory NICE needs to continue engaging with other HTA bodies on joint commissioning of advice and guidance, and utilising cohesive methodologies.”

In fact, NICE has not stopped working with global agencies on collaborative methodologies – one example being the Orbis Project, a joint programme involving the US, Canada, Switzerland, Singapore and Brazil that aims to review and approve promising cancer treatments months ahead of the EU.

“NICE is conscious of its key role in HTA,” says Lacharme, “and it wants to be sure that the UK remains a destination of choice for the life sciences sector. It is still working collaboratively with global health system partners, and more particularly with the MHRA, to design a streamlined process for licensing and evaluating new medicines.”

• Read the full article in pharmaphorum’s Deep Dive digital magazine

The post How will NICE fare in a post-Brexit world? appeared first on .

from https://pharmaphorum.com/views-analysis-market-access/how-will-nice-fare-in-a-post-brexit-world/

[organicgardendreams]

Rosa 'Souvenir du Docteur Jamain', another jewel that is cultivated at the Mottisfont Abbey Rose Garden. The dark red fading to royal violet blooms of this old Hybrid Perpetual rose, bred by Francois Lacharme 1865 in France, are absolutely breathtaking. Have in mind that I didn't use any filters nor did I edit this image, the flowers are naturally that striking. I am so glad that these Old Garden Roses are preserved at Mottisfont for all of us to enjoy! #souvenirdudocteurjamain #rose #roses #stunning #darkredroses #purpleroses #oldgardenroses #hybridperpetual #mottisfont #mottisfontabbey #mottisfontabbeygardens #mottisfontabbeyrosegarden #rosegarden #organicgardendreams #garden #gardens #gardening #england (at Mottisfont, National Trust)

[phoenix-dali-blog]

O Sister, Where Art Thou Vol.2 #bridal #fashioneditorial Photographer @dali.photographer Model @anyakolodinskaya @nastyamilicevic Designer @swanbridalsa MUAH @lacharmed Published on @gmaromagazine . . . . . . #Dali #fashionphotographer #LAphotographer #FashionAddict #fashionmodel #fashionweek #fashiondiaries #editorialfashion #theclassylifestyle #lovefashion #humanedge #fashionable #designerclothes #美人 #portraitsvisuals #portrait_society #portraitvision_ #globe_portraits #globe_people #nextonthepage #CreateToInspire #agencymodel #lamodels #dtla #california #canonphotography #bridalfashion (at Los Angeles, California) https://www.instagram.com/p/CnIc_jSP5ez/?igshid=NGJjMDIxMWI=

[frolickinggnomes]

[threadmosaicbyritajanikyan]

Photo by amazing @phoenix_dali HMUA @lacharmed Models @carla.e.n and @crystal.yueyaoli Stylist @jc_seguraa #MUA #MAKEUP #MAKEUPARTIST #graphiclines #PAINTING #ARTISTIC #EDITORIAL #PHOYOSHOOT #photographymakeup #photographer #Sandiego #stylist #hairstylist #influential #model #models #lamodels #follow #instagramlovers #instagram #blogger #professionalmua

[lexybowman]

@ananigrelli & @nicolejhamilton ✨ . Summertime sadness, fall feels. 🍂 . Photo: @phoenix_dali Makeup: @lacharmed Styles: @michelleechan__ // . . . . #lexyloveshair #sessionhairstylist #tbt #travelinghairstylist #fallfashion #bridalhair #texturedhair #hairart #sessionstylist #crafthairdresser #hairgoals #editorialhair #lifestyleblogger #hairmastered #perspective #hairstylist #hairblogger #hairbrained #haircreative #onlocation #travelinghairstylist #adventureawaits #explore #editorialphotography #modernsalon #hairinspo #hairgoals #crafthairdresser #travelgram #jointhejourney #naturalbeauty #glowgirl (at Yucca Valley, California) https://www.instagram.com/p/B41HLYeHgGa/?igshid=ncxds4hmn5ua

[78682homes]

Hommage à Paul Bouchet 78682 homes

http://www.78682homes.com/hommage-a-paul-bouchet

Hommage à Paul Bouchet

Paul Bouchet, rappelle Bernard Lacharme dans le bel hommage qu’il lui rend, se présentait comme ‘un vieux lutteur’. Avocat dans l’âme, sa parole ��tait une plaidoirie passionnée pour l’homme. Habité par la justice, il refusait ce que Péguy nommait les forces de l’habitude qui, toujours, conduisent à des pensées toutes faites jusqu’à se laisser habituer par des drames qu’on ne voit même plus. Paul Bouchet avait la vision d’un monde à construire, à reconstruire….

homms2013

#Informationsanté