#it sounds interesting

[tamblerdraws]

parkour civilization???? 🥺

Yes

Where to watch

[teslapunk3327]

After pre-ordering Torchwood: End Game after the Ianthology, and "I Hate Mondays", I am now considering whether Big Finish has become a genuine addiction for me.

[movietimegirl]

I'm not gonna lie, I don't know anything about Star Wars: The High Republic, the Era, or the characters. I haven't read books. All I know is that it's takes place about 400 years ago, WAY before Anakin is born. I'm gonna have to do research on this, I've been meaning to get into it.

[transingthoseformers]

There was this artist on tumblr that had a megop betrothal au and I'm just. Thinking about it.

They're not active anymore, but I still enjoyed it.

... also Megatron had boobs and I'm all about that.

Look the moment you said boobs I might've laughed

[stardial]

Your Gideonposting has reminded me of the book "hold me closer necromancer" which I love for two reasons. 1. Every chapter title is a classic rock lyric and 2. Sasquatches live in hiding because they're so hot everyone's lust upon seeing them would destroy society

this is true about sasquatches in real life too

[shepherd-posting]

thoughts on yuri 🎤

Uh.. No clue, never heard of it before!

Is it something to do with rescuing people? Or dogs?

[liveorganism]

will i read a fic with a really interesting concept but it has a my annoytp as the main pairing and another side pairing that i could care less about

[caramelmochacrow]

thinking of watch revue starlight...

[writeouswriter]

[elle-smells]

how does one boop someone

[reasonsforhope]

A new treatment combining ReCET and semaglutide could eliminate the need for insulin in type 2 diabetes, with 86% of participants in a study no longer requiring insulin therapy. The treatment was safe and well-tolerated, and further trials are planned to confirm these results.

Groundbreaking research presented at UEG Week 2024 introduces a promising new treatment approach for type 2 diabetes (T2D) that has the potential to greatly reduce or even eliminate the need for insulin therapy.

This innovative approach, which combines a novel procedure known as ReCET (Re-Cellularization via Electroporation Therapy) with semaglutide, resulted in the elimination of insulin therapy for 86% of patients.

Globally, T2D affects 422 million people... While insulin therapy is commonly used to manage blood sugar levels in T2D patients, it can result in side effects... and further complicate diabetes management. [Note: Also very importantly it's fucking bankrupting people who need it!!] A need therefore exists for alternative treatment strategies.

Study Design and Outcomes

The first-in-human study included 14 participants aged 28 to 75 years, with body mass indices ranging from 24 to 40 kg/m². Each participant underwent the ReCET procedure under deep sedation, a treatment intended to improve the body’s sensitivity to its own insulin. Following the procedure, participants adhered to a two-week isocaloric liquid diet, after which semaglutide was gradually titrated up to 1mg/week.

Remarkably, at the 6- and 12-month follow-up, 86% of participants (12 out of 14) no longer required insulin therapy, and this success continued through the 24-month follow-up. In these cases, all patients maintained glycaemic control, with HbA1c levels remaining below 7.5%.

Tolerability and Safety

The maximum dose of semaglutide was well-tolerated by 93% of participants, one individual could not increase to the maximum dose due to nausea. All patients successfully completed the ReCET procedure, and no serious adverse effects were reported.

Dr Celine Busch, lead author of the study, commented, “These findings are very encouraging, suggesting that ReCET is a safe and feasible procedure that, when combined with semaglutide, can effectively eliminate the need for insulin therapy.”

“Unlike drug therapy, which requires daily medication adherence, ReCET is compliance-free [meaning: you don't have to take it every day], addressing the critical issue of ongoing patient adherence in the management of T2D. In addition, the treatment is disease-modifying: it improves the patient’s sensitivity to their own (endogenous) insulin, tackling the root cause of the disease, as opposed to currently available drug therapies, that are at best disease-controlling.”

Looking ahead, the researchers plan to conduct larger randomized controlled trials to further validate these findings. Dr. Busch added, “We are currently conducting the EMINENT-2 trial with the same inclusion and exclusion criteria and administration of semaglutide, but with either a sham procedure or ReCET. This study will also include mechanistic assessments to evaluate the underlying mechanism of ReCET.”

-via SciTechDaily, October 17, 2024

--

Note: If it works even half as well as suggested, this could free so many people from the burden of the ongoing ridiculous cost of insulin. Pharma companies that make insulin can go choke (hopefully).

[viva-la-pluto-damn-you]

“Power tends to corrupt, and absolute power corrupts absolutely.”

-John Emerich Edward Dalberg Acton, English Historian, 1887

i don't know how you can "the curtains are just blue! ACAB lol" fucking Death Note of all pieces of media

this is a show for thirteen-year-old boys. the only writers I've seen who are less subtle about what they're going for were fucking Victorians.

[pickled-flowers]

Sex positivity is also about not calling Ace people prude and using virgin as an insult 👍 hope that helps

[breesperez139]

Dc x Dp Prompt #6

“I’m a twin”, Damian said one night. He could feel the narrowed eyes of his family drilling holes on his back in disbelief. Not that he could blame them. Damian had never so much as implied being raised with a companion, much less a sibling.

“I had a brother”. Damian paused to recollect himself. He had not said his brother’s name out loud in over 8 years.

“His name was… Danyal”. Damian hated the way his voice wavered, but he could not help it. Danyal was everything to him, his other half. Their heart beat as one and when one heart stopped beating, the other one died with it. At least until his family put his heart on metaphorical life support without ever realizing.

“Where is he now?” His father asked, voice filled with knowing grief and a hint of betrayal. It had in fact been 6 years since Damian first showed up on his doorstep.

“Up there”. All eyes shifted towards the specific star he was pointing to. “Right before he died, he promised me he’d guide me from the stars. Unfortunately, the stars are not visible in Gotham, so my brother is unable to be of much help unless I leave the city.”

“Your brother is Polaris, the North Star?” Tim questioned warily, most likely in attempts to not offend him. Damian was aware of how stupid it sounded, but Danyal had promised, and his brother never broke his promises.

“Yes. Danyal is with the stars now, just as he always wanted”

[inkskinned]

i love when words fit right. seize was always supposed to be that word, and so was jester. tuesday isn't quite right but thursday should be thursday, that's a good word for it. daisy has the perfect shape to it, almost like you're laughing when you say it; and tulip is correct most of the time. while keynote is fun to say, it's super wrong - i think they have to change the label for that one. but fox is spot-on.

most words are just, like, good enough, even if what they are describing is lovely. the night sky is a fine term for it but it isn't perfect the way november is the correct term for that month.

it's not just in english because in spanish the phrase eso si que es is correct, it should be that. sometimes other languages are also better than the english words, like how blue is sloped too far downwards but azul is perfect and hangs in the air like glitter. while butterfly is sweet, i think probably papillion is more correct, although for some butterflies féileacán is much better. year is fine but bliain is better. sometimes multiple languages got it right though, like how jueves and Πέμπτη are also the right names for thursday. maybe we as a species are just really good at naming thursdays.

and if we were really bored and had a moment and a picnic to split we could all sit down for a moment and sort out all the words that exist and find all the perfect words in every language. i would show you that while i like the word tree (it makes you smile to say it), i think arbor is correct. you could teach me from your language what words fit the right way, and that would be very exciting (exciting is not correct, it's just fine).

i think probably this is what was happening at the tower of babel, before the languages all got shifted across the world and smudged by the hand of god. by the way, hand isn't quite right, but i do like that the word god is only 3 letters, and that it is shaped like it is reflecting into itself, and that it kind of makes your mouth move into an echoing chapel when you cluck it. but the word god could also fit really well with a coathanger, and i can't explain that. i think donut has (weirdly) the same shape as a toothbrush, but we really got bagel right and i am really grateful for that.

grateful is close, but not like thunder. hopefully one day i am going to figure out how to shape the way i love my friends into a little ceramic (ceramic is very good, almost perfect) pot and when they hold it they can feel the weight of my care for them. they can put a plant in there. maybe a daisy.

[specialagentartemis]

Reading (listening to, as Homer intended) the Iliad making me go oh. Ohhh. I should have done this before I read Gideon the Ninth. I get it now.

Particularly thinking now about the tidbit that in early drafts, our beloved gray-eyed Necromancer Warden of the Sixth House was named Diomedes Sextus. For Diomedes, king of Argos, young, brave, noble, heroic. Favorite fighter of Athena, bestest friend of Odysseus. And, notably, fought gods and—well he didn’t win exactly. But he got them good.

And specifically, he fought and wounded Aphrodite; Aphrodite, who is also called Cytherea.

And then of course Tamsyn Muir said she decided to change his name so she could make the Sex Pal joke.

Palamedes is a less heroic, less fondly remembered character in the Trojan War, but according to Plato, he unrelatedly invented both number and the alphabet, so you keep that connection to scholarship even if that’s not the first association with him. More interestingly, imo, there’s also an Arthurian Knight of the Round Table named Palamedes, best known for his unrequited love for Isolde (and his apparent ultimately gracious acceptance of her choosing Tristan).

I think this is actually a super interesting shift in thematic naming focus: from favored-of-Athena, fought-gods-and-wounded-them to unrequited heterosexual love, but didn’t act like a dick about it.

Also y’know. Sex Pal