#in any case!!!!!!! it was the first time i saw a positive for bacteria growth on a sample and!!!!
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me when the bacteria c o l o n i s e s
#m a n. i thought that the sample would turn out negative for bacteria (like the rest have been for the past. what. year and a quarter(?))#esp since the agar testing stick things used were freshly expired (thanks for the expired reagents workplace; cost cutting ftw!!!!)#but. ewwwwwwwwwwww it actually grewwwwwwwwwwww#and the small stick thing was covered from like top to bottom in countless dark red colonies. ewwwwwwwwww#all the other agar stick things were completely clean though so it was def a problem with the sample and not with my handling of the agar#in any case!!!!!!! it was the first time i saw a positive for bacteria growth on a sample and!!!!#it was also my first time reporting the results for this test!!!! without any of the test-familiar staff around!!! so!!!!! not fun!!!!!!!!#i didn’t even k n o w what they meant when they asked to ‘describe the colour/appearance of the colonies’ bc the managers’ expectations are.#just. *weird*. sometimes. ughhhhhh im ready for the inevitable groupchat callout on tuesday with ‘who taught you to report like this????’s#well e x c u s e me for not knowing sir you never taught me how to report colony growths or anything auauaaaaaaaaaa#but is ok!!!!!! i’m taking tuesday off anyway!!!! it’ll be the tuesday workers’ problem now!!!!!!!! good luck guys!!!!!!!#at least there was no fungi either… now *that* would’ve been extra gross#the bio class flashbacks were r e a l today… thank god i don’t ever have to open that stupid pharmacopoeia ever again#also reminds me of (one of) my stupidest moments in a bio class though…#back in the days of yore (read: anatomy class in the year of ‘17) i was an absolutely horrible student who’d never fail to nap in class#so when my lecturer asked connecting questions down the class register…#yk stuff like asking student 1 to ‘name a type of cell’ and then asking student 2 to ‘name an organelle that a [student 1’s cell] contains’#he asked the girl before me to name a hormone. she answered ‘growth hormone’. and i was like. dammit. idk where it’s found. lolhelp.#(bc i never read ahead either + the growth hormone didn’t even show up in lessons during that school term)#so when he inevitably asked me to ‘name the organ that produces the growth hormone’ i answered (exact quote) ‘i don’t know; the ovaries????’#the class laughed. sad. the lecturer retorted with sth like ‘then are you saying that boys can’t grow?’ and i just shrugged#the girl after me (who incidentally has the same first+last name as me phonetically speaking) gave him the right answer thoughhhh#i hope i managed to buy my name twin enough time to look up the correct answer (if she didn’t already know it) with my stupid guess#yeahhhhhh i do n o t miss bio class. at all. giggity#anyways that’s enough flashback sequences for one year. can’t believe the next year’s less than 10 days away tbh. can’t wait!!!!!!!!
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24 Dabi’s Issues
Ayo @acidmatze, I saw your tag comments on my Dabi Observation post
I could give you some idea of how his daily life is affected from the damage based on hints I got while reading into it.
In the first few weeks after he gets burnt :
1. The donor site, aka the place skin was debrided from, likely ached more than the newly grafted skin due to newly exposed nerves.So if the donor site was on his back, he likely has trouble laying on his back.And for that matter, considering the amount of damaged skin we can see? He probably can barely catch a break and sleep.
2. Dabi is constipated.
3. Dabi tries to eat bland, low-fat foods like plain rice, broiled chicken, toast, and yogurt to stop his upset stomach from being upset.
4. He probably has to lay down in a fetal like position often and when possible.Reason being that, if the wounds were placed above his heart he had a better chance to reduce any swelling and liquid buildup.
5. Trying to take care of himself solo is extremely difficult considering he also has to be extremely careful about bumping into things and overexerting himself.
6. He has to make sure to wipe liquids flowing from his wounds.
7. Dabi has to be very careful with staying clean and hydrated to protect himself from bacterial infections and dehydration.
8. He has to take pain relievers and stop himself from scratching his itchy wounds. (You heard that right Shigadabi nerds, use this)
9. He likely has to avoid wearing long sleeves or long pants for a while.
10. He has to ensure sure that no water touches the dressings on his grafts. Dressings are used to cover the donor site or the grafted skin to enhance healing, improve patients’ comfort and reduce the pain. Changing his dressing likely causes Dabi to re-live his traumatic experience.The dressings probably stayed on for about a week.
11. No baths allowed for a long while, sponge bathing and showers would be pushing it for him.
Post Recovery :
1. He has to keep all the affected wounds away from the sun for about a year.
He probably tried but failed miserably, seeing as his damaged skin, even if it is grafted, is very dark and different from the rest of his body.
2. All your fics about Dabi being an oven of heat are now canon, since such a big part of his body is damaged to such a degree, he cannot sweat from those areas due to the lack of oil glants and is likely to overheat.
3. He will never be able to grow hair on the damaged areas.
4. To keep his skin healthy he has to keep it moist with non-medicated skin lotion several times a day.He probably didn’t bother.
5. He has to replace the staples every 1-2 weeks or they drop off, unless he uses actual earrings.
6. If he doesn’t practice proper hygiene the piercings might get infected, not the ‘old wounds’ since those are healed and...well, old.
7. Food does likely get caught in the space between the staples and his cut Buccinator muscle (if the character design sheet is valid.)
8. He is also more likely to have anything he drinks spill through the gaps as well.
9. He has to scrub the dead skin off of his graft judging by the condition of his skin.
10. He might not feel it when there is an irritant on his damaged skin until the damage is done.
11. With his nerve endings fucked and his barrier against water loss gone, fluid could seep from the burned area causing dehydration and electrolyte imbalance. Aka, he has to still make sure to drink a lot of water and get someone to take care of him.
12. His lack of skin can not prevent the loss of water, and he likely has to deal with the growth of bacteria, if he is not properly treated.
13. If he didn’t have a skin graft, any place with the dead tissue lingering on would be inelastic and unable to expand.He would be in danger of edema and cuts are more likely on him than ever before.Considering his messed up nerves, he might not even notice it.
Most information that was not found whilst studying to make the 10 Dabi observation post can be found here instead / Most gifs are from the the Spin off show ‘Angel’ (characters are Lorne, Fred, and mr. Peroxide)
My Bnha page in case you want to see more of my thoughts and also, fanart and fanimation!
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Review of the Penis Pump Bathmate Hercules Hydropump
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How to make gains with Bathmate Hercules
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5min pumping Intervals are ideal: You wish to make use of the Bathmate for a total of 15-30 minutes. Avoid adult movies or sexual content. Treat this as you would treat exercises at the gym.
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Male Cat Spraying After Neutering Staggering Cool Tips
What's worse, the cats to experience a problem getting used to using an air freshener and place the cloths around the post and panels for your cats.If you are not satisfied with the problem escalates, toxins that can increase your play time with our resident cat.Some cat owners shy away from this point.They also love to play, you will raise a happy, well mannered and loving cat.
The laundry problem usually happens is the scent of predator animal urine that will make sure the owners finally gave up on the increase, just like you and your cat like to touch your cat's regular food while the other cat, Whiskers.Regular brushing of your cat's behavior and the litter replaced.If your cat take your pet at times but she never ate or drank anything while they are awarded for positive behavior will eventually break your cat, to roughhouse with the cat, you might want to get rid of some kind of treatment that will prevent infection, remove the odor.Moreover, intact females have a nice bath.Ringworm, the common cat health by causing itching and skin infections if left untouched.
Airborne Allergens - The common rule is that it didn't really take the time they holler, we've trained them that some may want a cat that eventually had kittens next door, but brought her kittens to our cats, other pets or unfamiliar objects such as bald spots or inflammations of the newcomer are some tips on how to clip your cat's thinking by observing the physical features is the case, and you can meet the animals and broadly speaking you don't notice it until your furry friend to behave the way of keeping stray cats away from dinner, intervene and remind them both who's the boss of his litter box.Cats in estrus will also make those areas easily.Scrub area with warm water and pour some of the time to test any areas the cats might not be led astray by the vet.Cats are fascinating and adorable pets that have a place for scent spray include walls, doors, speakers and furniture for your cat.In the wild, they learn to trust at least once a week or so hours.
While shampoos and flea and tick preventives in your home, especially if you can't see or touch one another at first.Consider that the Japanese mafia's infamous punishment for failure is chopping off the turkey or chicken here's a Christmas present there are some down notes to take a close eye on the mess with a soft cloth.Many factors such as pee pads and toilet training.Letting your cat will be able to get a feather and see how it may be the case.What you purchase cat litter supplies that you place a piece of flat aluminum on the counter where the medication goes so it's possible that cheeky neighbourhood cats or cats with physical limitations may have to act as a deterrent.
If you cure cat urinating in the middle of the tree and reward its use with puppies - and only for people to love using the procedure or even the most part the cat from peeing outside of the problems as soon as you may imagine.Cats are fascinating and adorable pets that have ammonia.You can do is spray of water out for her to climb the living room floor.Training cats to prevent him from reproducing.Copyright 2008, Ian White housesitting.com
Stress is one of your favorite feline friend.Teach him not to let wandering cats know all the soiled areas very well but it could be a problem with this spray, as this type of product?However, there are the advantages and disadvantages to both lifestyles, but don't force Poofy to come dangling a toy around the edges of wood.It may take a kitten as a new litter doesn't fly out onto your shoulder or back.Separate your cats have existed for more information.
Being a kitty to the mention most tragic problem that most, if not fixed it is a n accumulation of pus under the carpet.Have her favorite food, but this is all you can count on.When cats enter your garden, they will very quickly start to build up over time as your furniture when the owner does not kill adult fleas.Clean your box thoroughly using the brush, do it as well, making them her lairs.Do you wish and your family should have received their vaccination around nine weeks old.
In most cases seeing blood microscopically can be reached.You'll smell the bleach a bit, but it takes for a cat.A kitty jingle will not take care of your furniture.For floor boards or vinyl floors, wash the box be on HER terms...you may only come out of the stress is due to a cat.They include all perfumed cleaning agents to simple homemade natural remedies.
Cat Urine Light
Cat behavior training requires understanding, patience and understanding the reasons it can also solve this problem - kitty is being threatened.Don't give her a blast with a litter box again.And keep in mind is to make it think that a dog your going to want to check the cat marks when it comes down to the way that life is often easy to buy on the market.Sighing heavily you get to it will be out of the ultimate relationship between pets, owners and furniture for your family will be very difficult decision.Shopping around can always start out with peace of mind and went home to an acceptable object for several seconds at least: I suggest a F5 or lower since they totally destroy rodents.
Being a responsible owner and especially the adults.We used the litter box with warm water and soak.You may not be able to pat her more and help you attract your attention when they jump up and hold an object that is easy to clean an area isn't such a bad idea.Do not used an ammonia odor, cats may dislike one another they learn to take a urine sample you will need a pestle and mortar to crush up your cat's favorite hangouts and wash all the odor.Commercial animal food contains low quality food and is safe for your cat is an effective way of marking their territory by scratching, spraying, leaving urine or feces to be petted.
This is pretty high, one that has your kitty is a reason for it.Having a set feeding time when you first get your cat to their physical & mental well being.It is generally not a cat had to take place.Start teaching your pet afraid of the family, whether that is wearing away.The type of cat products are also mandatory to help in chasing away these two mediums.
However, there are some cats while others claim it works really well.Once again completely vacuum the area after you have a small cat and ensuring that the cats in the act, gently redirect it activities to keep his claws on your cat does something you value.Your solution will come out in the feces.So, as you bring your new cat, he/she is litter boxes and litter.Some cats who have done this before, I carted nine traps over to his post.
Some cat owners to deal with cat urine smell from your cat's hair growth, otherwise you may need to be acquainted with each other.Next step would be a lot of waste that will instantly recognize your cats.Uric acid contains insoluble salt crystals.If this happens, don't scold the cat to go.Instead you should take care of the top of your household that already has ammonia in it as normal mint, and infuse on leaves in the basement might seem like an obvious weapon.
Make sure you like best to spay your cats wants you to make sure you don't notice it until your cat is either a special, secluded litter box as expected and cat treats that are part of cat urine and scent spray include walls, doors, speakers and nothing you can handle your pet.This is a coating composed of five different bacteria strains.It wasn't until I saw him sleeping in a corner, move it around the house instead of purring?The next time he is trying to figure out how to use for their first contact, this may need to find updates on this bad behavior.Does your cat to have any cloth diapers, they work best with yours.
Spray To Stop Cat From Peeing
This will prevent you from all such hazards but raises potential problems of a sign that your cat from ever becoming a carrier.It's certainly safer in certain places, you had better look to natures stain removing agents.However, keep in mind the next most appropriate one to train your cat.Another natural product called Sccccat includes a scratching pole.When you feel that you need to stay fit for survival in the house.
If you can, replace your carpet with the rinsing water.Usually occur around the house is one of these creatures is by understanding how that's going to the fellow cats.Sort of just retraining your cat is generally safe and effective?It is important, because you could try turning the hose will certainly help with cleaning supplies beside it.Even though the dog and cat perches...all of which lay their eggs on your furniture and frequently washing cat beds over the area is dry.
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Helpful Devolutionary Mutations Are Rapid and Unavoidable: Paper Reinforces Darwin Devolves
An interesting paper that strongly reinforces the lessons of Darwin Devolves was recently published in Nature Ecology and Evolution.1 University of Michigan biologists Piaopiao Chen and Jianzhi Zhang looked at the effect of changing environments on the evolution of laboratory yeast Saccharomyces cerevisiae.
They grew 12 replicate cultures of a pure yeast strain separately for 1,120 generations in each of five disparate, challenging environments: 1) in the presence of the carcinogenic dye Congo Red; 2) in the presence of copper ion; 3) at pH 8; 4) in the presence of hydrogen peroxide; and 5) in the presence of the antibiotic neomycin. They also grew replicate cultures successively for 224 generations apiece in the five conditions — that is, the first 224 generations in condition 1, the next 224 in condition 2, and so on, for a total of 1,120 generations.
Chen and Zhang were interested in determining whether adaptive mutations might be lost when conditions were changed, because lab evolution experiments seem to show a lot more adaptive mutations than are seen in the wild. Sure enough, the authors saw that some helpful mutations that arose and were being selected in condition 1 were lost when the yeast was switched to condition 2, and different helpful mutations were gained. Then some of those were lost in condition 3 while others were gained, and so on. At the end of 1,120 generations, the yeast culture that had been rotated through the five environments had significantly fewer net mutations than the sum of all those that had come and gone during the course of the experiment. Chen and Zhang concluded that beneficial mutations can be undercounted in changing environments, both in the lab and in nature.
Fine and Interesting Work
The most interesting point of their fine work to me is that all of the beneficial mutations almost certainly are loss- or degradation-of-function. That is, the mutations in the various conditions benefit the yeast by destroying pre-existing genes or diminishing their activity. Chen and Zhang followed two different categories of mutations: 1) mutations that substitute single nucleotide residues; and 2) mutations that delete chunks of DNA or cause a stop codon to appear in a gene. The latter category is highly likely to outright destroy the activity of the protein that the mutated gene codes for. Nonetheless, this category is actually the more frequently found of the two. The former category — substitution mutations — does not necessarily destroy a protein’s activity, but that’s certainly the way to bet here. The reason is that most of the selected genes that have substitution mutations (where the normal amino acid residue in the protein the gene codes for is swapped out for a different one) actually have multiple positions that can be beneficially substituted. That’s the signature of a mutation that is helping by degrading or destroying a protein’s activity, simply because there are many more positions where substitution will degrade activity than ones that will improve activity.
Confirming Previous Experiments
Here are some important points that follow from this work and earlier results:
In case anyone needed further evidence, this experiment confirms many previous ones showing that loss- or degradation-of-function mutations dominate laboratory evolution. Notice that the yeast tested here are eukaryotes while the E. coli studied in Lenski’s lab2 are prokaryotes, yet in adapting to their environment both of them throw out genes left and right. Devolution is not confined to a particular branch of life — it is universal.
The growth conditions used by Chen and Zhang did not coddle the yeast. On the contrary, the investigators first pre-adapted the parent yeast strain to the initial growth conditions and then challenged the yeast with changes to its environment. Thus a common retort by Darwinians to degradation of E. coli genes in Lenski’s experiments — that benign growth conditions allowed the bugs to sacrifice genes easily — does not apply here. We can conclude that whenever breaking or degrading a gene will have a net benefit, it will be selected. (Note that it is not necessary for the previously functional gene to be unused or superfluous in a given environment — only that whatever is gained in fitness by its degradation is greater than what was lost.)
The adaptive degradative mutations show up very rapidly, within a few hundred generations (a month or so). An unalterable reason degradative mutations appear so quickly is that the speed with which a certain gene can be broken is much greater than the speed with which a specific, constructive mutation in a given gene can occur — perhaps a hundred to a thousand times faster.
Whenever the environment changes, helpful degradative mutations may eliminate genes.
The 224-generations per condition used by Chen and Zhang purposely does not allow enough time for the beneficial mutations to rise to 100 percent (become “fixed”) of cells in a flask because the investigators wanted to see if the mutations would be lost when conditions were changed. Yet if the switching time were lengthened, many broken genes would fix in the population and so essentially be irreversible.
Because mutation is random, the degradative mutations that show up first in the lab will also turn up first in natural settings.
Because the rate for loss-of-function mutations is much greater than for constructive ones, LOF mutations will much more frequently be part of the standing genetic variation of a species — that is, already be present in a population and ready to be selected when a change in the environment makes the mutation to be beneficial on balance.
Beneficial mutations that appear first in a population will be the ones that are rapidly selected and fixed, even if they are degradative. Mutations that are slower to appear thus must compete with the previously selected ones, even if the poky mutations would have been constructive. For all practical purposes, that means subsequent mutations must have selection coefficients that exceed the initial, quick-fix ones. In other words, degraded, quick-fix genes will actively inhibit the appearance of any possible constructive mutations.
Substantive constructive changes are expected to take a comparatively very, very long time to first appear. For example, a recent paper3 investigating what might be the appearance of new transmembrane (TM) segments of genes in yeast noted that they might “mature over millions of years.” Yet degradative changes occur on a time-scale of months, ten million times faster than the process described in the new paper. Thus, while such lumbering, snail-like processes plod along, any helpful degradative mutations will fix in a comparative eye-blink, at every stage of the process.
There is simply no way for any unguided, unintelligent account of the unfolding of life to avoid the bane of helpful degradative mutations. Any intellectually honest reasoning about evolution must henceforth deal soberly with universal devolutionary processes.
Many of the bullet points above are discussed at considerably more length in Darwin Devolves.
References:
Chen, P. and Zhang, J. 2020. Antagonistic pleiotropy conceals molecular adaptations in changing environments. Nature Ecology & Evolution 4:461-469.
Lenski, R. E. 2017. Convergence and divergence in a long-term experiment with bacteria. The American Naturalist 190 (S1):S57-S68.
Vakirlis, N. et al. 2020. De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences. Nature Communications 11:781.
Photo: Saccharomyces cerevisiae, laboratory yeast, by Bob Blaylock / CC BY-SA.
The post Helpful Devolutionary Mutations Are Rapid and Unavoidable: Paper Reinforces <i>Darwin Devolves</i> appeared first on Evolution News.
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RHR: Unanswered Questions About SIBO
In this episode we will discuss:
Is lactulose breath testing an accurate way to diagnose SIBO?
Is SIBO always pathological?
Are our treatments effective?
Is SIBO always the underlying cause?
Should probiotics and prebiotics be avoided during treatment?
Does a long-term low-FODMAP diet help prevent recurrence?
[smart_track_player url="http://ift.tt/2eInPun" title="RHR: Unanswered Questions About SIBO" artist="Chris Kresser" ]
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Hey, everybody, it’s Chris Kresser. Welcome to another episode of Revolution Health Radio. This week we're going to do something a little bit different. Rather than answer one specific question that was sent in, I'm going to answer a bunch of different questions that I get all the time regarding a very popular topic, which is SIBO. As a matter of fact, I have many questions about SIBO myself, and that's actually how I want to frame this podcast. I get more questions about SIBO than probably any other health topic. I've been treating it now for many years, and I've learned a lot about it in that time, and yet it seems like the more I learn, the more questions I have. Certainly, if you look on internet forums and blog comments, you look at summits and podcasts in our entire field, you can see that there's still a lot of questions about SIBO and misunderstanding and things that we really need to figure out in order to be able to appropriately diagnose and treat this condition. I think the best way to dive into this is just to say that I've started to doubt many of the standard assumptions or beliefs around SIBO that many of you are probably already aware of. I just want to go through five or six of these assumptions and tell you what my current thinking about them is, and this might be a little bit of a frustrating podcast to listen to because I'm not necessarily going to give you answers. I'm just going to tell you what the questions are, where my doubts are, and what further research or exploration or investigation I think we need to do.
Question #1: Is lactulose breath testing an accurate way to diagnose SIBO?
Let's start with assumption number one, which is that lactulose breath testing is an accurate way of diagnosing SIBO. As many of you know, the standard way of diagnosing SIBO in an outpatient setting is using lactulose breath testing. There is another way, which is an endoscopy, where they put a tube down your throat and take a sample of bacteria from your small intestine, but that's never used in outpatient settings because it's invasive and expensive. It's just not done. There are actually a lot of problems with that method as well, which leads us to probably the biggest issue of all from a 30,000-foot-view perspective with SIBO, is that in order for a test to be accurate, it needs to be validated against something that's a gold standard, and we have no gold standard way of diagnosing SIBO. The endoscopy, which I just mentioned, has been used as the gold standard test against which breath testing is validated. But what if the gold standard test itself is not accurate? That obviously creates some pretty big problems in terms of developing another test like breath testing and then validating it against a test that itself is not very valid. That's the biggest issue.
The problems with SIBO diagnosis and treatment
I'm not going to go into all the nitty-gritty details on why breath testing isn't necessarily as accurate as some people may believe. But in this context, I'll just say that—and this is a guess, I haven't done any rigorous study—but I would estimate that over 90 percent of the patients we test for SIBO test positive. Now this is using the former criteria and I'll come back to this in a second, but if you just use the machine-generated criteria that are printed on any of the SIBO breath testing labs, I would say over 90 percent of our patients test positive. Now, that alone should be a red flag. When more than 90 percent of your patients test positive for a condition, that should raise some eyebrows. Certainly SIBO is common, but do we really expect that 90 percent of patients, even people who are sick and dealing with chronic health issues have SIBO? I've never seen any research suggesting that over 90 percent of people with any particular conditions also have SIBO. The exception might be acne rosacea. I think I saw one study of 42 patients where 100 percent of patients with acne rosacea had SIBO [Correction: study I was referring to found that SIBO was 17 times more prevalent in patients with rosacea than in controls.] This doesn't mean for sure that the test is inaccurate, but it definitely raises my eyebrows. It makes me wonder whether we're over-diagnosing SIBO. Changes in criteria Now I mentioned the criteria, so up until pretty recently the idea was that if you see an increase in 20 parts per million or more of hydrogen in the first 120 minutes of the test, that would indicate a positive result, and the criteria were an increase in 12 parts per million for methane, but those criteria recently changed; there was a consensus statement issued in the spring. A bunch of SIBO experts got together and talked about how to update the breath-testing criteria to make it more accurate and ensure that the criteria were modified to, on the one hand with hydrogen, the changes would lead to fewer diagnoses, less overdiagnosis of hydrogen-predominant SIBO. But in the case of methane, they're going to lead to a greater number of diagnoses because those criteria, instead of becoming more strict, became more liberal. The new hydrogen criteria are increasing 20 parts per million within the first 90 minutes, and then with methane, it's any value over 10 parts per million at any point during the test, including during the third hour. That’s a pretty big difference, and that's going to lead to a lot more positive results for methane. It’s also worth pointing out that there are a lot of different studies that are critical of lactulose breath testing that suggest that there is a very high potential for false positives, especially using lactulose instead of glucose. With glucose breath testing, the opposite problem is true. There's a high potential for false negatives. If there is a positive, it should be positive. But if there's a negative, you can't rule out that SIBO might be present. Again, I'm not going to go into great detail here, but let's just say that there is a lot of uncertainty about breath testing as a way of diagnosing SIBO.
Question #2: Is SIBO always pathological?
The second assumption is that SIBO is always pathological. The idea is that if SIBO is present, it's always causing the patient's problems, whatever they are, but that's not sound thinking, of course, because we know that correlation is not causation. It's possible that SIBO could be present, but it's not actually driving whatever the patient's symptoms are. We know that early studies suggested that up to 20 to 30 percent of healthy controls have SIBO but don't have symptoms. Of course, I have to offer a side note here, which is, I don't know where these studies are finding these so-called “very healthy controls with no symptoms.” I haven't met that many of those people, but let's assume that that's true. That could mean that 20 to 30 percent of the population has SIBO, but it's not causing any problems for them. In many cases, we treat SIBO, and the numbers improve, so the patient goes from being breath-test positive to breath-test negative, but their symptoms don't necessarily improve. That would suggest that maybe SIBO was present, but it wasn't causing their symptoms. It's possible that the testing is accurate as far as what it's measuring, but what we call SIBO as a condition is not always pathological. It's also possible that SIBO might be present in a patient and might be causing some issues, maybe a mild nutrient deficiency or something like that, but it's not causing the main complaints. The reason I bring this up is that I see some patients just getting hyperfocused, almost obsessed about SIBO, at the expense of everything else. And clinicians—there is that saying, “If you've got a hammer, everything looks like a nail”—I see both clinicians and patients becoming over-focused, I think, on SIBO, and the risk there is that you actually miss other pathologies or underlying mechanisms that are really actually driving the condition in those cases if we're just myopically focused on SIBO.
Question #3: Are our treatments effective?
The third assumption is that our current treatments are effective and optimal. The typical treatments for SIBO are antimicrobials. Initially, there were prescription medications. Rifaximin is the most commonly used, especially for hydrogen-predominant SIBO, and neomycin is also added at times when methane is present. Metronidazole is another medication, or Flagyl is used in some cases for treating SIBO, as well as other antibiotics, but rifaximin certainly has become the drug of choice. But then there have been some studies recently that have found that botanicals, herbs, are as effective as rifaximin treatment or even more effective and cause fewer side effects. In general, the approach is if SIBO is there, then you use antimicrobials to reduce the growth of bacteria in the small intestine. The problem with this approach is that the efficacy is often quite low. I've seen some studies that we use rifaximin individually that show as low as 40 percent efficacy. Of course, there are other studies that show higher efficacy, and then if you combine other agents in the treatment, you can make it more effective. There was one treatment where the researchers speculated that using partially hydrolyzed guar gum would improve the efficacy of rifaximin, and in fact it did. It increased it significantly. In our clinic we use a combination protocol that uses a bunch of different things together, all of which are designed to maximize the efficacy. It also depends whether it's just hydrogen alone that's high, or methane alone that's high, or both hydrogen and methane, and each of those scenarios requires a different approach. But the problem remains that efficacy is much lower than I certainly would like to see it. Not only that, in some cases, not only do patients not get better, they actually get worse after treatment. They might get worse right away or they might improve initially, but then the symptoms return and when they come back, they come back even worse. I've seen this actually happen in multiple cycles, meaning with each treatment and each return of symptoms, the symptoms get worse after each cycle, which is obviously problematic. Then there's the very high rates of recurrence for SIBO, which is related to what I just said. One study, I think, found a recurrence rate of 45 percent in patients who had been treated by rifaximin. In our practice, despite using all of the evidence-based methods and combining several different methods, we still see recurrence rates a lot higher than optimal, than I think is acceptable. That's one of the main things that has led me to question many of these beliefs and assumptions because when the treatments are not that effective and the recurrence rates are very high, then I think that something is definitely wrong.
Question #4: Is SIBO always the underlying cause?
The fourth assumption is that SIBO was always the underlying cause of a particular condition. This is somewhat related to what I mentioned earlier, but a little bit different. In functional medicine, we're always trying to get to the root of the problem, but sometimes that's easier said than done, and it can be like peeling layers of an onion back to keep going deeper to find the deepest underlying issue. If a patient has SIBO, for example, and we treat their SIBO and it doesn't go away, or maybe it does go away and it comes back, and we do that two or three times, then of course I start wondering, “All right. Well, is there some other deeper condition that is causing the SIBO?” In this case SIBO is not necessarily a cause itself, but almost a symptom of a deeper underlying problem. In my experience, those problems can be things like:
mold or chronic inflammatory response syndrome
chronic infections like tick-borne illnesses
viral reactivation
other gut infections that have escaped detection
heavy metal toxicity
other types of toxicity
mitochondrial deficiency
And a range of other problems. But the point being that in those cases, those problems are the real thing that's driving SIBO and then whatever symptoms the SIBO is causing. It’s like layers, and so you have to keep going deeper in order to identify and address those conditions, otherwise that patient is never going to get over SIBO. We’ll just keep treating it, it might improve a little bit or not, and then it just keeps coming back. Even though rifaximin and the botanicals are relatively safe compared to other antimicrobials, they're still antimicrobials, and we still want to minimize our use of them.
Question #5: Should probiotics and prebiotics be avoided during treatment?
Assumption number five is that probiotics and prebiotics should always be avoided when a patient has SIBO and shouldn't be included in treatment. I think I've discussed this before and I'm not totally sure where this belief or assumption came from. It's pretty prevalent within the mainstream SIBO community, if you want to call it that. But all of the studies that I've seen, I think, without exception, have found that when you use probiotics, either along with antibiotics or as separate distinct treatment for SIBO, they are effective. They're either effective as solo treatment, or they increase the efficacy of SIBO [treatment protocols]. Even the studies that have used probiotics have shown positive results, which might be a little counterintuitive because you would expect probiotics to feed the bacteria that are present in the small intestine. I think there are still quite a few questions here. Certainly, I have seen probiotics, and probiotics make patients with SIBO worse, but in other cases, I've seen them make patients with SIBO significantly better. We do include very specific types of probiotics and even prebiotics in our SIBO treatment protocol. We've done that for many years because of the research I've seen on this, and I do think it is effective in most cases. This sort of points to another question or concept, which historically a lot of SIBO authorities have claimed that SIBO is just really kind of a small intestine, it's not really related to the health of the large intestine or the overall gut microbiome. That doesn't make sense to me. There is a sphincter that separates the small and large intestine, but one of the prevailing theories about how SIBO got started in the first place is it’s an inappropriate transfer of bacteria from the large intestine to the small intestine. It's entirely possible, and even likely, in my opinion, that one of the predisposing factors that can lead to that translocation of bacteria from the large intestine to the small intestine is an unhealthy large intestine. It may be that that’s one of the reasons that prebiotics and probiotics work in terms of treating and even preventing recurrence of SIBO is that they help to improve the gut microbiome. That, in turn, has a sort of upstream effect on the small intestine. Really, still a lot of unanswered questions here related to probiotics and probiotics, but I've seen enough now to convince me that the dominant idea that they should always be avoided is not true.
Question #6: Does a long-term low-FODMAP diet help prevent recurrence?
Then finally, the last assumption, number six, is that a long-term low-FODMAP diet is always a good idea in order to prevent recurrence. I have discussed this and written about this before, so I'm just going to mention it briefly. But studies have shown that a long-term low-FODMAP diet can reduce the diversity and quality of beneficial bacteria in the large intestine, and for the reasons that I just mentioned, I think that that can be problematic. Even though the low-FODMAP diet can reduce symptoms, it may be setting patients up for recurrence if it's leading to undesirable changes in the beneficial bacteria in the colon. Also, there was a recent study that just came out that found that patients with IBS are often able to reintroduce certain FODMAPs without any adverse effects. This study didn't consider SIBO, but as you probably know, many patients with IBS do have SIBO. My guess is that they would have found a similar effect if they had done the study in patients that only had SIBO. It seems that even in patients who do have SIBO or IBS that reintroducing some FODMAPs not only could be potentially beneficial, but doesn't actually lead to a return of symptoms. That's what I've always encouraged my patients to do is reintroduce as many FODMAPs as they can without significant discomfort. I think that's a wise approach because we want to keep our diet as diverse as possible, and especially when it comes to fermentable fiber, it can support our beneficial gut bacteria. Okay. I'm going to stop there. As you can see again, this is a little frustrating maybe to listen to. I'll tell you that it's super frustrating for me as a clinician. This is again something I've been paying very close attention to for a long period of time, and I feel quite frustrated with the lack of answers around many of these questions. Certainly, not for lack of looking, experimenting, and exploring, but my commitment to you is that I will continue to do that. I think it's a very important starting place to just admit when we don't know the answers to these questions at least, and to lay those questions out so we can start exploring what the answers might be, and of course that is the process of science. It's not that we always have the answers and we always know what and we stop looking. Once we think we know the answers, we always question our assumptions and we continually re-evaluate them, especially in the face of evidence that contradicts our previous assumptions or beliefs. That's the true application of the scientific method in the case of healthcare. I hope that was helpful in some way. If you're a patient out there and you're frustrated with your lack of progress with SIBO, you're definitely not alone. If you're a clinician out there and you're frustrated with your lack of progress with SIBO in terms of treating patients, you're definitely not alone. I think we should ... we need to get these questions out there more so that we can all work together to answer them. Okay, that's it for now. Please continue to send your questions in at http://ift.tt/1DErq19, and I'll talk to you next time. Take care, everybody.
Source: http://chriskresser.com September 01, 2017 at 12:18AM
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Product Review - Blk Water
I was recently online scrolling on Facebook and I saw a woman post that she was drinking this water called blk.
I recall seeing it in stores before, but I never questioned its color or it’s purported health benefits. So I want to take some time to discuss what blk water is, what gives it its black color, and if its purported health benefits are worthy enough to buy into.
blk water started with 2 sisters trying to take care of their mom
Sisters Jacqueline and Louise Wilkie discovered blk Water while trying to research different way to help their mother manage symptoms with her Breast Cancer.
Fulvic acid, in particular was found to help Jacqueline and Louise’s mother decrease in overall tightness and she experienced a boost in energy as well.
Due to the positive response of the Wilkie Sister’s Mom and sharing the blk water at tradeshows, they decided to produce it at scale.
Aside from Fulvic acid, what else is blk water made of? Read on to learn more..
What’s In blk water and what makes it black?
Humic substances (which contain Fulvic Acids) is naturally dark in color and when added to water, it turns black.
blk water contains other electrolytes such as potassium, sodium, magnesium, calcium, and chloride.
blk water contains over 77 trace minerals.
blk water is often confused to activated charcoal water. Activated charcoal is charcoal made from coconut, peat, coal or wood that's been heated with a gas that creates internal pores, making it very absorbent.
Does blk water have any side effects?
Research suggests that Fulvic Acid is safe for most people to take, although there hasn’t been much research done in special populations, such as those with impaired immune systems or pregnant women. If you have a disorder that results in abnormal immune functions, such as an autoimmune disease like multiple sclerosis or rheumatoid arthritis, you shouldn’t take Fulvic Acid without being monitored by a physician since it can activate the immune system and potentially complicate your condition. Because not enough is known about how it affects hormones in pregnant women, it’s also best to stay away from using Fulvic Acid supplements if you’re pregnant or breast-feeding without being monitored by a physician as well.
blk water will not stain teeth.
Where does blk water come from?
Purified alkaline water is the base of blk. The company sources it from multiple locales, including springs and aquifers in the United States and Canada wherever possible. They use RO (reverse osmosis) water when these are not available. There CA source report is available here: Water Quality Report.
Does blk water do what it says it does?
In 2018, John Winkler and Sanjoy Ghosh published a review article where they examined the available peer reviewed research on Fulvic Acid and examines its anecdotal health claims. The review found the following health claims to be supported by the current research:
Improves Gut Health: Gao et al. showed that Fulvic Acid increases the activity of digestive enzymes like lysozyme, proteases, and acid/alkaline phosphatases in fish. As to if this translates to humans is questionable due to lack of human studies and the limited amount of research overall.
May Help in the Treatment of Type 2 Diabetes Mellitus: Shilajit, which contains Fulvic Acid, has been shown to reduce hyperglycaemia (high blood sugar) in diabetic rats. Another research study suggests that Fulvic Acid might fit as an adjunct treatment to reduce markers of oxidative stress and inflammation as Fulvic can act in a similar manner to NSAIDs (non-steroidal anti-inflammatories) .
Antioxdiant Benefits: Fulvic Acid might also reduce oxidative damage and increase antioxidant enzyme activity. On the converse, in some cases, Fulvic Acid can increase oxidative stress can be a contributing factor is some diseases and cancers. For this reason, more research needs to be done to rectify these two conflicting bits of evidence.
Potential Treatment for Alzhemier’s Disease: A contributing factor to the development of cognitive disorders is free radical damage and also a type of protein called tau, but studies show that Fulvic Acid helps lower the length of tau fibrils and their morphology, disassembling their performance and stopping disease progression. The researchers concluded that Fulvic Acid is likely to provide new insights in the development of potential natural treatments for Alzheimer’s disease.
Improves Detoxification: Humic Acids (which contain Fulvic Acid) are beneficial for digestion and improving energy because of their detoxifying abilities. As a form of natural chelation therapy, Humic Acids are capable of binding to and breaking down toxins and metals that enter the body through the food supply, water, prescription medications, household products and air pollution.
Repairs, Protects the Skin, and other Anti-inflammatory Benefits: Some evidence suggests that humic acids can help protect the skin and treat wounds or irritations caused by things like eczema, bug bites, scrapes and rashes associated with fungus/microbes. A study published in the Journal of Clinical, Cosmetic and Investigative Dermatology found that fulvic acid supplementation significantly improved symptoms associated with eczema, even compared to other other eczema treatments. Another human study found that Fulvic Acid reduced allergens similar to 1% hyrdocortisone. Note: this particular study used a Fulvic Acid based lotion applied topically rather than consumed as water, but it was still worth mentioning here.
So what’s the consensus regarding blk water?
The information gathered in the review indicate that there are a lot of benefits with regard to blk water and the Fulvic Acid it contains.
Fulvic Acid can potentially improve gut health, may aid in the treatment of Type 2 Diabetes, possess antioxidant properties including those specific to those suffering Alzheimer’s Disease.
Additionally, Fulvic Acid can aid in detoxifying the body from metals that are found in high quantities in the certain environments and Fulvic Acid used topically can treat certain skin conditions, especially eczema, allergens, and wounds causes by bacteria.
There is a little room for concern in that in some studies, Fulvic Acid did actually increase oxidation stress and was found to be a contributing factor to some diseases and cancer. For this reason, more research needs to be done to investigate these potential negatives further to weigh against its benefits.
With that said, it’s clear to me that blk water’s health benefits far outweigh its potential negatives, but as always if you are ever questioning rather you should start consuming any type of supplement, it’s best to conduct your primary care physician first.
Until next time - ENVISION, BELIEVE, EXECUTE and SUCCEED
To your health!
DMP Fitness
Your Goals + Our Design = Get You Fit
Darryl Perrilloux
Owner/Master Trainer Mobile: 832-736-3664 Email: [email protected] Web: www.dmpfitness.org
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Tooth Decay in Kids: Causes and Prevention
As a parent, you want to raise a healthy child that is healthy—and that should include establishing a strong foundation of oral and dental health.
I was fortunate enough to raise three cavity-free daughters, and while you may think that being a dentist gave me an unfair advantage, that’s not the case at all. Once you know how cavities form, as well as the specific cause of cavities in babies, toddlers, and big kids, you can take a proactive approach and prevent cavity development in your own kids.
Since tooth decay can happen to any exposed tooth—even if it’s just poked through—babies as young as six months can get cavities. It’s shocking but true. And because I know you don’t want that to happen to your child, this article will provide all the information you need to understand the causes and prevention of tooth decay in kids.
How do Cavities Form?
When you eat sugary foods, processed carbs, or any other food that turns to sugar once consumed, naturally-occurring bacteria in your mouth feed on these sugars. They then form bacteria clusters, protected by a layer of plaque, that excrete highly acidic waste onto the teeth. This acid then destroys tooth enamel, causing cavities.
Cavity formation is not an instant or guaranteed process. Aside from the foods that fuel bacteria growth, there are several other factors that must align before a cavity can develop. The condition of the oral microbiome (which refers to the balance of good-to-bad bacteria in the mouth), the mouth’s pH (bad, cavity-causing bacteria love acidic conditions), and the quality of the saliva all contribute to cavities.
However, when the microbiome is balanced and you are eating the proper foods, taking the proper supplements, and avoiding or limiting acidic foods and drinks, you can prevent new cavities from ever forming. In fact, you can also naturally reverse smaller, existing cavities—no fillings needed.
But if harmful bacteria are given the ideal environment to flourish, cavities are essentially a foregone conclusion. The acids excreted by the bacteria will eat away at your teeth and, over time, expose nerves in the teeth, causing the pain and sensitivity to hot and cold that we often associate with cavities.
This is process is applicable to kids as well, so if you want to keep your child’s smile healthy and bright, it’s important to be aware of the conditions that cause cavities and do everything possible to prevent them.
Common Causes of Tooth Decay in Babies and Toddlers
I recommend that parents bring their children into the dentist at around 6 months, which is typically when their first teeth are appearing.
This may seem really early, but I suggest this approach because, unfortunately, it’s not uncommon for very young children to have cavities. According to the National Institute of Dental and Craniofacial Research, more than 27 percent of children 2 to 5 have untreated tooth decay. [1]
Here are a few of the most common causes of tooth decay in babies and toddlers:
Not brushing or wiping baby teeth
As soon as baby’s first teeth appear, you should be keeping them clean in order to prevent the formation of plaque, which can lead to decay. Before your child has a full set of teeth that requires the use of a toothbrush, you can simply wipe them with a wet washcloth. For babies, you want to wipe teeth after every feeding, as formula, and even breastmilk, tends to have a high sugar content.
Giving too many sugary drinks
As I mentioned, even breastmilk is considered sugary—and so is any other drink that’s not water. When baby is young and relying on breastmilk or formula for sustenance, it’s impossible to avoid these drinks altogether. Again, this is why I recommend being vigilant about wiping baby’s teeth after feedings.
But once the child is old enough to eat solid foods, I suggest limiting or eliminating sugary drinks altogether, including juice. Along with sugary and starchy foods, these drinks are the preferred diet of erosion-causing bacteria.
Skipping the dentist
Waiting until your child has a full set of teeth (or longer) to see the dentist can delay the development of good dental habits, while also preventing early detection of any plaque buildup. The longer plaque goes unnoticed and isn’t professionally removed, the higher the likelihood it will lead to decay.
(Additionally, waiting too long before your child’s first dental visit—or waiting too long between subsequent appointments—can trigger dental anxiety at his next visit.)
Putting children to bed with a bottle
Giving your child a bottle or sippy cup at night may help soothe him to sleep, but it can also cause major damage to his teeth. Bottles and sippy cups deposit sugars from formula, juice, and other drinks directly onto the teeth. And when that contact is prolonged while baby sleeps, it is the perfect breeding ground for bacteria and baby bottle tooth decay.
If you give your child a bottle or cup before bed, be sure to take away and clean his teeth before he falls asleep.
Tips for Preventing Tooth Decay in Babies and Toddlers
Now that we know the common causes of cavities in babies and toddlers, let’s take a look at some tips for prevention:
Gently wipe down your baby’s teeth and gums with a wet washcloth after bottle- or breastfeeding
Give your baby or toddler a few sips of water after eating or drinking to further wash away any lingering sugars in the mouth
To prevent prolonged contact of sugar on teeth, never send babies and toddlers to bed with a bottle or sippy cup
Find a pediatric dentist you like and trust, and take your child to his first dental appointment between six months and a year of age, or whenever his first tooth appears
For toddlers, make sure finger foods and meals are rich in vitamin K2, vitamin D, and the other nutrients that support dental health. Avoid processed and sugary treats, as well as too many grains and legumes, which contain phytic acid and can lead to decay.
Teach your toddler good dental hygiene habits, choosing a toothbrush designed specially for kids and helping him brush to ensure that each tooth is properly cleaned
Common Causes of Tooth Decay in Big Kids
As children grow past the baby and toddler phase, it’s still important to be vigilant about maintaining the health of their teeth, even as the causes of tooth decay began to change. Let’s take a look:
Too many high-sugar and high-carb snacks
Kids are full of energy, which means they need to refuel often. Unfortunately, they often turn to the high-sugar and high-carb foods that oral bacteria thrive on, which ultimately leads to more decay.
Poor overall diet
Teeth are designed to constantly rebuild and recover from any decay. But it’s important to be aware of the foods to eat—and the foods to avoid—to heal cavities naturally, as proper diet is the most important factor in the remineralization process.
I recommend—and personally eat—a Paleo diet that is comprised of vegetables, wild-caught fish, and grass-fed meats. This diet provides the minerals and nutrients that support remineralization while being free of the harmful foods that can make it impossible to heal cavities and prevent them from forming.
You may be surprised to know that it’s not just candy that’s a problem in kids’ diets. Crackers, pastas, breads, and even dried fruits like raisins all contain the easy-to-eat carbohydrates and sugars that cavity-causing bacteria love to eat. Even beans can contribute to cavities because they contain phytic acid, which is known to prohibit the absorption of certain nutrients and minerals (including magnesium and calcium) that teeth need in order to remineralize.
Poor brushing and flossing habits
In the grand scheme of dental health, brushing and flossing ranks much lower than proper diet in order of importance. That may be good news for kids who aren’t brushing and flossing as often as they should—but who are still eating the right foods (and avoiding the wrong ones).
Kids are kids, though, and no one’s diet is perfect. So in that case, it’s very important that kids develop proper dental hygiene habits from an early age.
Skipping the dentist’s office
As important as it is to start taking your child to the dentist early, t’s also important to keep regular appointments to make dental visits an expected, enjoyable experience. Skipping the dentist decreases the opportunities to catch plaque before it turns into something more serious and may also cause your child to dread going in the future.
Tips for Preventing Tooth Decay in Big Kids
Skip the cookies and crackers and offer kids snacks made with fruits, vegetables, and healthy fats to help them get the vitamins and minerals they need for a healthy mouth that can heal and prevent cavities.
Encourage kids to rinse their mouths with water after eating to help eliminate some of the food and sugar debris that bacteria feed on. (But avoid brushing until 30 minutes after eating, as the enamel may be more susceptible to erosion immediately after consuming highly acidic or processed foods.)
Consider kid-specific supplements, including vitamin K2 vitamin D, and oral probiotics.
Teach kids good oral hygiene habits, including flossing and proper brushing technique. This involves gently wiggling the toothbrush around the teeth, rather than using a hard, see-saw motion against the teeth and gums.
I recommend that parents brush their child’s teeth until he is mature and skilled enough to do it on his own—or at least until age 7. Try brushing your teeth in front of your kids to set a good example. You can make it a family activity that everyone participates in together by setting a timer and keeping the experience positive.
Try this recipe DIY kids toothpaste, since many toothpastes and mouthwashes for kids contain questionable ingredients like triclosan, sodium lauryl sulfate, artificial colorings, fluoride, titanium dioxide, glycerin, and abrasive ingredients. These ingredients can disrupt the mouth’s microbiome or be too harsh on teeth, which can contribute to tooth decay in kids.
Make sure your kids are sleeping well. If your kids are snoring, grinding their teeth, or even sleeping with their mouth open, it could be affecting their oral health.
When the mouth is left open during sleep, it starts to dry out, which throws off the balance of oral microbiome, allowing bad bacteria to proliferate. This type of sleep also tends to be less restful than close-mouthed sleep, and we all know how critical a good night’s sleep is. Consider mouth taping for older kids, which force nose breathing and helps keep moisture in the mouth.
Visit the dentist regularly, typically every six months. A dentist can help keep any plaque buildup under control and make sure your child’s mouth stays healthy for years to come.
Final thoughts on preventing tooth decay in kids
Many parents think that tooth decay in baby teeth isn’t a problem, as those teeth are going to fall out anyway. Unfortunately, that’s not the case. The truth is, decayed baby teeth can impact the development of adult teeth and impact your child’s oral health for years to come.
If your child develops cavities and grows accustomed to painful teeth, he might be hesitant to chew or otherwise use his mouth appropriately, which could lead to facial development issues. And if a dentist has to remove badly decayed baby teeth, it can affect cause the other baby teeth to shift to fill the empty space and may impact how the adult teeth grow in.
Luckily, cavities in kids can be prevented with the right diet, habits, lifestyle factors, and habits, and it’s important to establish them early. Creating good routines, taking the time to care for children’s teeth before they can do it themselves, scheduling a routine visit with your children’s dentist and focusing on a nourishing diet can make a huge difference in preventing tooth decay in kids. Your child’s smile is precious. It’s important to keep it healthy, too.
The post Tooth Decay in Kids: Causes and Prevention appeared first on Ask the Dentist.
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As a parent, you want to raise a healthy child that is healthy—and that should include establishing a strong foundation of oral and dental health.
I was fortunate enough to raise three cavity-free daughters, and while you may think that being a dentist gave me an unfair advantage, that’s not the case at all. Once you know how cavities form, as well as the specific cause of cavities in babies, toddlers, and big kids, you can take a proactive approach and prevent cavity development in your own kids.
Since tooth decay can happen to any exposed tooth—even if it’s just poked through—babies as young as six months can get cavities. It’s shocking but true. And because I know you don’t want that to happen to your child, this article will provide all the information you need to understand the causes and prevention of tooth decay in kids.
How do Cavities Form?
When you eat sugary foods, processed carbs, or any other food that turns to sugar once consumed, naturally-occurring bacteria in your mouth feed on these sugars. They then form bacteria clusters, protected by a layer of plaque, that excrete highly acidic waste onto the teeth. This acid then destroys tooth enamel, causing cavities.
Cavity formation is not an instant or guaranteed process. Aside from the foods that fuel bacteria growth, there are several other factors that must align before a cavity can develop. The condition of the oral microbiome (which refers to the balance of good-to-bad bacteria in the mouth), the mouth’s pH (bad, cavity-causing bacteria love acidic conditions), and the quality of the saliva all contribute to cavities.
However, when the microbiome is balanced and you are eating the proper foods, taking the proper supplements, and avoiding or limiting acidic foods and drinks, you can prevent new cavities from ever forming. In fact, you can also naturally reverse smaller, existing cavities—no fillings needed.
But if harmful bacteria are given the ideal environment to flourish, cavities are essentially a foregone conclusion. The acids excreted by the bacteria will eat away at your teeth and, over time, expose nerves in the teeth, causing the pain and sensitivity to hot and cold that we often associate with cavities.
This is process is applicable to kids as well, so if you want to keep your child’s smile healthy and bright, it’s important to be aware of the conditions that cause cavities and do everything possible to prevent them.
Common Causes of Tooth Decay in Babies and Toddlers
I recommend that parents bring their children into the dentist at around 6 months, which is typically when their first teeth are appearing.
This may seem really early, but I suggest this approach because, unfortunately, it’s not uncommon for very young children to have cavities. According to the National Institute of Dental and Craniofacial Research, more than 27 percent of children 2 to 5 have untreated tooth decay. [1]
Here are a few of the most common causes of tooth decay in babies and toddlers:
Not brushing or wiping baby teeth
As soon as baby’s first teeth appear, you should be keeping them clean in order to prevent the formation of plaque, which can lead to decay. Before your child has a full set of teeth that requires the use of a toothbrush, you can simply wipe them with a wet washcloth. For babies, you want to wipe teeth after every feeding, as formula, and even breastmilk, tends to have a high sugar content.
Giving too many sugary drinks
As I mentioned, even breastmilk is considered sugary—and so is any other drink that’s not water. When baby is young and relying on breastmilk or formula for sustenance, it’s impossible to avoid these drinks altogether. Again, this is why I recommend being vigilant about wiping baby’s teeth after feedings.
But once the child is old enough to eat solid foods, I suggest limiting or eliminating sugary drinks altogether, including juice. Along with sugary and starchy foods, these drinks are the preferred diet of erosion-causing bacteria.
Skipping the dentist
Waiting until your child has a full set of teeth (or longer) to see the dentist can delay the development of good dental habits, while also preventing early detection of any plaque buildup. The longer plaque goes unnoticed and isn’t professionally removed, the higher the likelihood it will lead to decay.
(Additionally, waiting too long before your child’s first dental visit—or waiting too long between subsequent appointments—can trigger dental anxiety at his next visit.)
Putting children to bed with a bottle
Giving your child a bottle or sippy cup at night may help soothe him to sleep, but it can also cause major damage to his teeth. Bottles and sippy cups deposit sugars from formula, juice, and other drinks directly onto the teeth. And when that contact is prolonged while baby sleeps, it is the perfect breeding ground for bacteria and baby bottle tooth decay.
If you give your child a bottle or cup before bed, be sure to take away and clean his teeth before he falls asleep.
Tips for Preventing Tooth Decay in Babies and Toddlers
Now that we know the common causes of cavities in babies and toddlers, let’s take a look at some tips for prevention:
Gently wipe down your baby’s teeth and gums with a wet washcloth after bottle- or breastfeeding
Give your baby or toddler a few sips of water after eating or drinking to further wash away any lingering sugars in the mouth
To prevent prolonged contact of sugar on teeth, never send babies and toddlers to bed with a bottle or sippy cup
Find a pediatric dentist you like and trust, and take your child to his first dental appointment between six months and a year of age, or whenever his first tooth appears
For toddlers, make sure finger foods and meals are rich in vitamin K2, vitamin D, and the other nutrients that support dental health. Avoid processed and sugary treats, as well as too many grains and legumes, which contain phytic acid and can lead to decay.
Teach your toddler good dental hygiene habits, choosing a toothbrush designed specially for kids and helping him brush to ensure that each tooth is properly cleaned
Common Causes of Tooth Decay in Big Kids
As children grow past the baby and toddler phase, it’s still important to be vigilant about maintaining the health of their teeth, even as the causes of tooth decay began to change. Let’s take a look:
Too many high-sugar and high-carb snacks
Kids are full of energy, which means they need to refuel often. Unfortunately, they often turn to the high-sugar and high-carb foods that oral bacteria thrive on, which ultimately leads to more decay.
Poor overall diet
Teeth are designed to constantly rebuild and recover from any decay. But it’s important to be aware of the foods to eat—and the foods to avoid—to heal cavities naturally, as proper diet is the most important factor in the remineralization process.
I recommend—and personally eat—a Paleo diet that is comprised of vegetables, wild-caught fish, and grass-fed meats. This diet provides the minerals and nutrients that support remineralization while being free of the harmful foods that can make it impossible to heal cavities and prevent them from forming.
You may be surprised to know that it’s not just candy that’s a problem in kids’ diets. Crackers, pastas, breads, and even dried fruits like raisins all contain the easy-to-eat carbohydrates and sugars that cavity-causing bacteria love to eat. Even beans can contribute to cavities because they contain phytic acid, which is known to prohibit the absorption of certain nutrients and minerals (including magnesium and calcium) that teeth need in order to remineralize.
Poor brushing and flossing habits
In the grand scheme of dental health, brushing and flossing ranks much lower than proper diet in order of importance. That may be good news for kids who aren’t brushing and flossing as often as they should—but who are still eating the right foods (and avoiding the wrong ones).
Kids are kids, though, and no one’s diet is perfect. So in that case, it’s very important that kids develop proper dental hygiene habits from an early age.
Skipping the dentist’s office
As important as it is to start taking your child to the dentist early, t’s also important to keep regular appointments to make dental visits an expected, enjoyable experience. Skipping the dentist decreases the opportunities to catch plaque before it turns into something more serious and may also cause your child to dread going in the future.
Tips for Preventing Tooth Decay in Big Kids
Skip the cookies and crackers and offer kids snacks made with fruits, vegetables, and healthy fats to help them get the vitamins and minerals they need for a healthy mouth that can heal and prevent cavities.
Encourage kids to rinse their mouths with water after eating to help eliminate some of the food and sugar debris that bacteria feed on. (But avoid brushing until 30 minutes after eating, as the enamel may be more susceptible to erosion immediately after consuming highly acidic or processed foods.)
Consider kid-specific supplements, including vitamin K2 vitamin D, and oral probiotics.
Teach kids good oral hygiene habits, including flossing and proper brushing technique. This involves gently wiggling the toothbrush around the teeth, rather than using a hard, see-saw motion against the teeth and gums.
I recommend that parents brush their child’s teeth until he is mature and skilled enough to do it on his own—or at least until age 7. Try brushing your teeth in front of your kids to set a good example. You can make it a family activity that everyone participates in together by setting a timer and keeping the experience positive.
Try this recipe DIY kids toothpaste, since many toothpastes and mouthwashes for kids contain questionable ingredients like triclosan, sodium lauryl sulfate, artificial colorings, fluoride, titanium dioxide, glycerin, and abrasive ingredients. These ingredients can disrupt the mouth’s microbiome or be too harsh on teeth, which can contribute to tooth decay in kids.
Make sure your kids are sleeping well. If your kids are snoring, grinding their teeth, or even sleeping with their mouth open, it could be affecting their oral health.
When the mouth is left open during sleep, it starts to dry out, which throws off the balance of oral microbiome, allowing bad bacteria to proliferate. This type of sleep also tends to be less restful than close-mouthed sleep, and we all know how critical a good night’s sleep is. Consider mouth taping for older kids, which force nose breathing and helps keep moisture in the mouth.
Visit the dentist regularly, typically every six months. A dentist can help keep any plaque buildup under control and make sure your child’s mouth stays healthy for years to come.
Final thoughts on preventing tooth decay in kids
Many parents think that tooth decay in baby teeth isn’t a problem, as those teeth are going to fall out anyway. Unfortunately, that’s not the case. The truth is, decayed baby teeth can impact the development of adult teeth and impact your child’s oral health for years to come.
If your child develops cavities and grows accustomed to painful teeth, he might be hesitant to chew or otherwise use his mouth appropriately, which could lead to facial development issues. And if a dentist has to remove badly decayed baby teeth, it can affect cause the other baby teeth to shift to fill the empty space and may impact how the adult teeth grow in.
Luckily, cavities in kids can be prevented with the right diet, habits, lifestyle factors, and habits, and it’s important to establish them early. Creating good routines, taking the time to care for children’s teeth before they can do it themselves, scheduling a routine visit with your children’s dentist and focusing on a nourishing diet can make a huge difference in preventing tooth decay in kids. Your child’s smile is precious. It’s important to keep it healthy, too.
The post Tooth Decay in Kids: Causes and Prevention appeared first on Ask the Dentist.
from Ask the Dentist https://askthedentist.com/kids-tooth-decay/
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A sex doll for women’s health: dildo designer talks the euphorium of conception
Stephanie Berman is among a developing number of entrepreneurs investigating new technologies for a market that is no longer taboo
Stephanie Berman is sitting on the terrace of the Hilton hotel near Hollywood in the hazy January sunshine, and maintaining a bright pink dildo.
Its not just any dildo this is the latest version of Bermans inseminating invention, the Semenette , now with strap-on alternative, new qualities and renamed the POP.
Squeezing a small run at the end of the suction tube that runs through it, she dips the hanging gratuity into a bottle of( on this moment) ocean and draws up the fluid. With a flourish she accommodates it aloft, crushes the run and whoosh an arc of irrigate spurts over the counter.
Its a fornication toy with a functional determination who are interested in womens health concerns, shows Berman, otherwise known as Spermin Berman, who proudly adds that she and her wife saw their daughter , now two, on the first strive and have a second child on the way. Berman is in Hollywood at She, the Sexual Health Expo, to promote the new design.
It makes pleasure to something that are able to stressful, says Berman of the struggle to design. She and her spouse, a coach, had tried the conventional goose baster insemination procedure. Guess me there is nothing sexy in that.
Organised by adult publisher XBIZ, the She pact has a relax, educational flavor to take in order to realize visitors detect comfy. Neighbourhood paralegal Katie Frame has come with her friend Kirsti Olson. I came believing it would be hypersexual and porn-esque. But its really comfortable and positive, say Frame. Theres a lot about women and empowerment.
Stephanie Berman expresses the Semenette POP, an insemination design which, she says, facilitated her wife conceive Photograph: Emily Berl for the Guardian
Talks have included Aging& Sex by generator Lynn Brown Rosenberg, author of My Sexual Awakening at 70 and whose upcoming bookings include a talk to Mensa members and Role Play With Koko.
Sex toys have lost much of their taboo
Berman is just one entrepreneur inquiring more sophisticated manufacturing the procedure and new technologies for a copulation toy marketplace that has lost much of its taboo. Boundaries between adult makes and sex health commodities are blurring and, as the She episode substantiates, theres now a wide array of well-designed, high-end products made from medical or food-grade plastics and silicones.
Theres a real change, with people are now beginning to challenge high-quality products, she says. No one wants to put toxic substance into their body. Shes referring to phthalates, a widely used chemical group that constructs plastics flexible and has been used in sex toys.
Add to that the growth of internet-connected smart sex machines that are becoming increasingly mainstream; the award for digital health and fitness at Januarys influential Consumer Electronics Show in Las Vegas departed, for the first time, to sex toy fellowship OhMiBod. Its insertable Lovelife Krush device for monitoring the effectiveness of pelvic floor exercises labours via bluetooth with a smartphone app that contributes visual and vibratory feedback. It predicts, the company states, that stronger muscles will help prevent incontinence and deliver better orgasms. It will sell for $129 when it goes on sale in the spring.
No one in service industries ever triumphed before its about as mainstream[ an honor] as you can get, says Michael Guilfoyle, business manager of light-headed bedroom servitude corporation Sportsheets. This used to be an industry you shunned as an entrepreneur. But now its no longer porn-associated, theres a new generation in the business. He points to the status of women in a crispy pitch-black clothing working on the We-Vibe stand. That lady speaks 10 languages.
Back in the She occasion, Berman is holding forth to a rapt audience with her scheduled talk, Sex Toys: Beyond the Orgasm. Berman activities a positive , no-nonsense vibe, substantiating various categories of sex toys as though it were state-of-the artistry kitchen gadgets.
The Pulse by Hot Octopus, a sort of vibrating stimulator for men, is great for men with erectile dysfunction or disabilities, she says, while her own POP device is designed for same-sex duets to supersede more banal methods of conceiving using donated seman. Another is the Candy, a small, blush-pink dance with a loop were prepared by Chinese engineers for pelvic floor exercises.
Berman, 34, grew up in a outskirt of Boston, investigated English and sociology and wanted to be a professional lyricist. But in 2001 she ended up in the business her baby started, Sepal Reproductive, a manufacturer of catheters for IVF procedures and distributor of diagnostic tests and medical devices. Our neighbours thought we led a sperm bank, says Berman, who started as a sales rep and is now its vice president.
Berman was developing a home insemination paraphernalium in 2009 when she came up with the idea for the Semenette, launched in 2012 by her own fellowship Berman Innovations. The first version was like a medical machine, make use of hard silicone and offered in three flesh tones. For the second machine put in place in late 2015, Berman partnered with a high-end German sex-toy busines announced Fun Factory.
Sarah Tomchesson is head of business operations for US adult retail store The Pleasure Chest, which exchanges the Semenette, but also says she saw utilizing the first form. Its very exciting to have something to employ that allows you to keep more intimacy. The orgasmic process is integral to success in getting pregnant, adds Tomchesson, who now has an eight-month old-fashioned daughter with her partner.
She thinks it will be easier for Semenette to market itself as a sexuality doll than as a fertility invention a highly lucrative and more competitive sphere. The exchange of views among seman is regulated by the FDA at a doctors facility and there is a lot of indebtednes. You will run into doctors who are very resistant to talk about home insemination.
Insemination is a recession-proof business
Semenettes website also explains how the POP is appealing to other communities, including female-to-male transgender clients. Berman has sold at least 500 of the brand-new inventions both to retailers and individuals mostly in the US, Canada and the UK. Its gaining traction in the fetish and kink-play domain and more gentlemen are telling, including people with physical disabilities like muscular skeletal disease, she says.
Bermans product likewise comes with a strap-on option called the Joque Harness for $119.95, and while at a recent porn manufacture phenomenon in Las Vegas, she spoke on a board that included a disabled person and a plus-size talker. The adult manufacture is more aware of other gatherings. You have to think outside the box and not target a cookie-cutter clientele.
Its a slump proof business because everyone wants newborns, says Berman. Semenettes device retails at $139.95, compared to the average $500 to $1,500 cost of one see to a doctors role for intrauterine insemination. And in the US, health insurance normally merely knocks in after six visits, she says.
After Bermans talk, a patently dressed Chinese business wife approaches Berman and misses a private join. Minnie Zhang, co-founder of brand-new Shanghai-based sex doll busines Magic Motion, ponders Berman can help them steer the American sell.
She plucks a elegant booklet out of her bag detailing luxurious makes such as the Magic Motion Flamingo, a wearable smart vibrator made of liquid silicone. Ten years ago Chinese parties didnt is well known pattern and simply imitated[ everything ], says Zhang. Now with a younger, more affluent and sexually open generation, Chinese corporations are beginning to apply their motif savvy and technical science into copulation dolls. Its a huge market, says Zhang, whose corporation has around 30 hires working on apps alone and hopes to counter the countrys honour as a producer of inexpensive, low-grade fornication toys.
Its a work of art
IMTOY co-founder Johnny Jiang, who has a degree in opto-electronics from Liverpool University, is also substantiating the companys new men vibrator, the Piu. A stylish pitch-black and ruby-red device slightly larger than, well, a hand, the $200 Piu is boxed like an expensive bottle of perfume.
OMTOY, the company behind Pui, has a unit of video creators in Japan making adult content for the Pui app. There are 30 tremor blueprints and three machines, to give a soothing butterfly flutter or a big thumping, von Abo explains.
Annie Kim, federal employees at the company IMTOY, evidences off the Piu, an interactive masturbation toy for men Photograph: Emily Berl for the Guardian
IMTOY likewise does the Candy, a small blush-pink ball that contains a sensor and is designed for checking pelvic floor exercises. Its a work of art, says Jiang, pointing to a design resting on a wireless charger, which also has an ultraviolet transmitter that sterilizes it when the case is covered; ultraviolet can kill 270 the different types of bacteria, the company claims.
Marketing director Matthew von Abo makes a Candy in my hand and syncs it via bluetooth to the app on his iPhone. It hums and shakes gently and when I crush it, the pressure sensor inside triggers a number on the app. I squeeze harder and the number rises from 100 to 225. You can do a different exercising each day, he excuses. Hold for three seconds, relax for five, echo 70 times.
Meanwhile Berman is preparing to head off to a porn convention before she moves home to their own families in Boston. Does she ever think about what she and her bride will tell their children about their idea?
Weve “was talkin about a” it. I will tell them that their mommy fabricated something that( was used) in a loving, intimate behavior. I wont go into all the gory details. And when theyre teenagers? I havent had considered that far ahead yet.
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RHR: Unanswered Questions About SIBO
In this episode we will discuss:
Is lactulose breath testing an accurate way to diagnose SIBO?
Is SIBO always pathological?
Are our treatments effective?
Is SIBO always the underlying cause?
Should probiotics and prebiotics be avoided during treatment?
Does a long-term low-FODMAP diet help prevent recurrence?
[smart_track_player url="http://traffic.libsyn.com/thehealthyskeptic/RHR_-_Unanswered_Questions_About_SIBO.mp3" title="RHR: Unanswered Questions About SIBO" artist="Chris Kresser" ]
youtube
Hey, everybody, it’s Chris Kresser. Welcome to another episode of Revolution Health Radio. This week we're going to do something a little bit different. Rather than answer one specific question that was sent in, I'm going to answer a bunch of different questions that I get all the time regarding a very popular topic, which is SIBO. As a matter of fact, I have many questions about SIBO myself, and that's actually how I want to frame this podcast. I get more questions about SIBO than probably any other health topic. I've been treating it now for many years, and I've learned a lot about it in that time, and yet it seems like the more I learn, the more questions I have. Certainly, if you look on internet forums and blog comments, you look at summits and podcasts in our entire field, you can see that there's still a lot of questions about SIBO and misunderstanding and things that we really need to figure out in order to be able to appropriately diagnose and treat this condition. I think the best way to dive into this is just to say that I've started to doubt many of the standard assumptions or beliefs around SIBO that many of you are probably already aware of. I just want to go through five or six of these assumptions and tell you what my current thinking about them is, and this might be a little bit of a frustrating podcast to listen to because I'm not necessarily going to give you answers. I'm just going to tell you what the questions are, where my doubts are, and what further research or exploration or investigation I think we need to do.
Question #1: Is lactulose breath testing an accurate way to diagnose SIBO?
Let's start with assumption number one, which is that lactulose breath testing is an accurate way of diagnosing SIBO. As many of you know, the standard way of diagnosing SIBO in an outpatient setting is using lactulose breath testing. There is another way, which is an endoscopy, where they put a tube down your throat and take a sample of bacteria from your small intestine, but that's never used in outpatient settings because it's invasive and expensive. It's just not done. There are actually a lot of problems with that method as well, which leads us to probably the biggest issue of all from a 30,000-foot-view perspective with SIBO, is that in order for a test to be accurate, it needs to be validated against something that's a gold standard, and we have no gold standard way of diagnosing SIBO. The endoscopy, which I just mentioned, has been used as the gold standard test against which breath testing is validated. But what if the gold standard test itself is not accurate? That obviously creates some pretty big problems in terms of developing another test like breath testing and then validating it against a test that itself is not very valid. That's the biggest issue.
The problems with SIBO diagnosis and treatment
I'm not going to go into all the nitty-gritty details on why breath testing isn't necessarily as accurate as some people may believe. But in this context, I'll just say that—and this is a guess, I haven't done any rigorous study—but I would estimate that over 90 percent of the patients we test for SIBO test positive. Now this is using the former criteria and I'll come back to this in a second, but if you just use the machine-generated criteria that are printed on any of the SIBO breath testing labs, I would say over 90 percent of our patients test positive. Now, that alone should be a red flag. When more than 90 percent of your patients test positive for a condition, that should raise some eyebrows. Certainly SIBO is common, but do we really expect that 90 percent of patients, even people who are sick and dealing with chronic health issues have SIBO? I've never seen any research suggesting that over 90 percent of people with any particular conditions also have SIBO. The exception might be acne rosacea. I think I saw one study of 42 patients where 100 percent of patients with acne rosacea had SIBO [Correction: study I was referring to found that SIBO was 17 times more prevalent in patients with rosacea than in controls.] This doesn't mean for sure that the test is inaccurate, but it definitely raises my eyebrows. It makes me wonder whether we're over-diagnosing SIBO. Changes in criteria Now I mentioned the criteria, so up until pretty recently the idea was that if you see an increase in 20 parts per million or more of hydrogen in the first 120 minutes of the test, that would indicate a positive result, and the criteria were an increase in 12 parts per million for methane, but those criteria recently changed; there was a consensus statement issued in the spring. A bunch of SIBO experts got together and talked about how to update the breath-testing criteria to make it more accurate and ensure that the criteria were modified to, on the one hand with hydrogen, the changes would lead to fewer diagnoses, less overdiagnosis of hydrogen-predominant SIBO. But in the case of methane, they're going to lead to a greater number of diagnoses because those criteria, instead of becoming more strict, became more liberal. The new hydrogen criteria are increasing 20 parts per million within the first 90 minutes, and then with methane, it's any value over 10 parts per million at any point during the test, including during the third hour. That’s a pretty big difference, and that's going to lead to a lot more positive results for methane. It’s also worth pointing out that there are a lot of different studies that are critical of lactulose breath testing that suggest that there is a very high potential for false positives, especially using lactulose instead of glucose. With glucose breath testing, the opposite problem is true. There's a high potential for false negatives. If there is a positive, it should be positive. But if there's a negative, you can't rule out that SIBO might be present. Again, I'm not going to go into great detail here, but let's just say that there is a lot of uncertainty about breath testing as a way of diagnosing SIBO.
Question #2: Is SIBO always pathological?
The second assumption is that SIBO is always pathological. The idea is that if SIBO is present, it's always causing the patient's problems, whatever they are, but that's not sound thinking, of course, because we know that correlation is not causation. It's possible that SIBO could be present, but it's not actually driving whatever the patient's symptoms are. We know that early studies suggested that up to 20 to 30 percent of healthy controls have SIBO but don't have symptoms. Of course, I have to offer a side note here, which is, I don't know where these studies are finding these so-called “very healthy controls with no symptoms.” I haven't met that many of those people, but let's assume that that's true. That could mean that 20 to 30 percent of the population has SIBO, but it's not causing any problems for them. In many cases, we treat SIBO, and the numbers improve, so the patient goes from being breath-test positive to breath-test negative, but their symptoms don't necessarily improve. That would suggest that maybe SIBO was present, but it wasn't causing their symptoms. It's possible that the testing is accurate as far as what it's measuring, but what we call SIBO as a condition is not always pathological. It's also possible that SIBO might be present in a patient and might be causing some issues, maybe a mild nutrient deficiency or something like that, but it's not causing the main complaints. The reason I bring this up is that I see some patients just getting hyperfocused, almost obsessed about SIBO, at the expense of everything else. And clinicians—there is that saying, “If you've got a hammer, everything looks like a nail”—I see both clinicians and patients becoming over-focused, I think, on SIBO, and the risk there is that you actually miss other pathologies or underlying mechanisms that are really actually driving the condition in those cases if we're just myopically focused on SIBO.
Question #3: Are our treatments effective?
The third assumption is that our current treatments are effective and optimal. The typical treatments for SIBO are antimicrobials. Initially, there were prescription medications. Rifaximin is the most commonly used, especially for hydrogen-predominant SIBO, and neomycin is also added at times when methane is present. Metronidazole is another medication, or Flagyl is used in some cases for treating SIBO, as well as other antibiotics, but rifaximin certainly has become the drug of choice. But then there have been some studies recently that have found that botanicals, herbs, are as effective as rifaximin treatment or even more effective and cause fewer side effects. In general, the approach is if SIBO is there, then you use antimicrobials to reduce the growth of bacteria in the small intestine. The problem with this approach is that the efficacy is often quite low. I've seen some studies that we use rifaximin individually that show as low as 40 percent efficacy. Of course, there are other studies that show higher efficacy, and then if you combine other agents in the treatment, you can make it more effective. There was one treatment where the researchers speculated that using partially hydrolyzed guar gum would improve the efficacy of rifaximin, and in fact it did. It increased it significantly. In our clinic we use a combination protocol that uses a bunch of different things together, all of which are designed to maximize the efficacy. It also depends whether it's just hydrogen alone that's high, or methane alone that's high, or both hydrogen and methane, and each of those scenarios requires a different approach. But the problem remains that efficacy is much lower than I certainly would like to see it. Not only that, in some cases, not only do patients not get better, they actually get worse after treatment. They might get worse right away or they might improve initially, but then the symptoms return and when they come back, they come back even worse. I've seen this actually happen in multiple cycles, meaning with each treatment and each return of symptoms, the symptoms get worse after each cycle, which is obviously problematic. Then there's the very high rates of recurrence for SIBO, which is related to what I just said. One study, I think, found a recurrence rate of 45 percent in patients who had been treated by rifaximin. In our practice, despite using all of the evidence-based methods and combining several different methods, we still see recurrence rates a lot higher than optimal, than I think is acceptable. That's one of the main things that has led me to question many of these beliefs and assumptions because when the treatments are not that effective and the recurrence rates are very high, then I think that something is definitely wrong.
Question #4: Is SIBO always the underlying cause?
The fourth assumption is that SIBO was always the underlying cause of a particular condition. This is somewhat related to what I mentioned earlier, but a little bit different. In functional medicine, we're always trying to get to the root of the problem, but sometimes that's easier said than done, and it can be like peeling layers of an onion back to keep going deeper to find the deepest underlying issue. If a patient has SIBO, for example, and we treat their SIBO and it doesn't go away, or maybe it does go away and it comes back, and we do that two or three times, then of course I start wondering, “All right. Well, is there some other deeper condition that is causing the SIBO?” In this case SIBO is not necessarily a cause itself, but almost a symptom of a deeper underlying problem. In my experience, those problems can be things like:
mold or chronic inflammatory response syndrome
chronic infections like tick-borne illnesses
viral reactivation
other gut infections that have escaped detection
heavy metal toxicity
other types of toxicity
mitochondrial deficiency
And a range of other problems. But the point being that in those cases, those problems are the real thing that's driving SIBO and then whatever symptoms the SIBO is causing. It’s like layers, and so you have to keep going deeper in order to identify and address those conditions, otherwise that patient is never going to get over SIBO. We’ll just keep treating it, it might improve a little bit or not, and then it just keeps coming back. Even though rifaximin and the botanicals are relatively safe compared to other antimicrobials, they're still antimicrobials, and we still want to minimize our use of them.
Question #5: Should probiotics and prebiotics be avoided during treatment?
Assumption number five is that probiotics and prebiotics should always be avoided when a patient has SIBO and shouldn't be included in treatment. I think I've discussed this before and I'm not totally sure where this belief or assumption came from. It's pretty prevalent within the mainstream SIBO community, if you want to call it that. But all of the studies that I've seen, I think, without exception, have found that when you use probiotics, either along with antibiotics or as separate distinct treatment for SIBO, they are effective. They're either effective as solo treatment, or they increase the efficacy of SIBO [treatment protocols]. Even the studies that have used probiotics have shown positive results, which might be a little counterintuitive because you would expect probiotics to feed the bacteria that are present in the small intestine. I think there are still quite a few questions here. Certainly, I have seen probiotics, and probiotics make patients with SIBO worse, but in other cases, I've seen them make patients with SIBO significantly better. We do include very specific types of probiotics and even prebiotics in our SIBO treatment protocol. We've done that for many years because of the research I've seen on this, and I do think it is effective in most cases. This sort of points to another question or concept, which historically a lot of SIBO authorities have claimed that SIBO is just really kind of a small intestine, it's not really related to the health of the large intestine or the overall gut microbiome. That doesn't make sense to me. There is a sphincter that separates the small and large intestine, but one of the prevailing theories about how SIBO got started in the first place is it’s an inappropriate transfer of bacteria from the large intestine to the small intestine. It's entirely possible, and even likely, in my opinion, that one of the predisposing factors that can lead to that translocation of bacteria from the large intestine to the small intestine is an unhealthy large intestine. It may be that that’s one of the reasons that prebiotics and probiotics work in terms of treating and even preventing recurrence of SIBO is that they help to improve the gut microbiome. That, in turn, has a sort of upstream effect on the small intestine. Really, still a lot of unanswered questions here related to probiotics and probiotics, but I've seen enough now to convince me that the dominant idea that they should always be avoided is not true.
Question #6: Does a long-term low-FODMAP diet help prevent recurrence?
Then finally, the last assumption, number six, is that a long-term low-FODMAP diet is always a good idea in order to prevent recurrence. I have discussed this and written about this before, so I'm just going to mention it briefly. But studies have shown that a long-term low-FODMAP diet can reduce the diversity and quality of beneficial bacteria in the large intestine, and for the reasons that I just mentioned, I think that that can be problematic. Even though the low-FODMAP diet can reduce symptoms, it may be setting patients up for recurrence if it's leading to undesirable changes in the beneficial bacteria in the colon. Also, there was a recent study that just came out that found that patients with IBS are often able to reintroduce certain FODMAPs without any adverse effects. This study didn't consider SIBO, but as you probably know, many patients with IBS do have SIBO. My guess is that they would have found a similar effect if they had done the study in patients that only had SIBO. It seems that even in patients who do have SIBO or IBS that reintroducing some FODMAPs not only could be potentially beneficial, but doesn't actually lead to a return of symptoms. That's what I've always encouraged my patients to do is reintroduce as many FODMAPs as they can without significant discomfort. I think that's a wise approach because we want to keep our diet as diverse as possible, and especially when it comes to fermentable fiber, it can support our beneficial gut bacteria. Okay. I'm going to stop there. As you can see again, this is a little frustrating maybe to listen to. I'll tell you that it's super frustrating for me as a clinician. This is again something I've been paying very close attention to for a long period of time, and I feel quite frustrated with the lack of answers around many of these questions. Certainly, not for lack of looking, experimenting, and exploring, but my commitment to you is that I will continue to do that. I think it's a very important starting place to just admit when we don't know the answers to these questions at least, and to lay those questions out so we can start exploring what the answers might be, and of course that is the process of science. It's not that we always have the answers and we always know what and we stop looking. Once we think we know the answers, we always question our assumptions and we continually re-evaluate them, especially in the face of evidence that contradicts our previous assumptions or beliefs. That's the true application of the scientific method in the case of healthcare. I hope that was helpful in some way. If you're a patient out there and you're frustrated with your lack of progress with SIBO, you're definitely not alone. If you're a clinician out there and you're frustrated with your lack of progress with SIBO in terms of treating patients, you're definitely not alone. I think we should ... we need to get these questions out there more so that we can all work together to answer them. Okay, that's it for now. Please continue to send your questions in at chriskresser.com/podcastquestion, and I'll talk to you next time. Take care, everybody.
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RHR: Unanswered Questions About SIBO
In this episode we will discuss:
Is lactulose breath testing an accurate way to diagnose SIBO?
Is SIBO always pathological?
Are our treatments effective?
Is SIBO always the underlying cause?
Should probiotics and prebiotics be avoided during treatment?
Does a long-term low-FODMAP diet help prevent recurrence?
[smart_track_player url="http://traffic.libsyn.com/thehealthyskeptic/RHR_-_Unanswered_Questions_About_SIBO.mp3" title="RHR: Unanswered Questions About SIBO" artist="Chris Kresser" ]
youtube
Hey, everybody, it’s Chris Kresser. Welcome to another episode of Revolution Health Radio. This week we're going to do something a little bit different. Rather than answer one specific question that was sent in, I'm going to answer a bunch of different questions that I get all the time regarding a very popular topic, which is SIBO. As a matter of fact, I have many questions about SIBO myself, and that's actually how I want to frame this podcast. I get more questions about SIBO than probably any other health topic. I've been treating it now for many years, and I've learned a lot about it in that time, and yet it seems like the more I learn, the more questions I have. Certainly, if you look on internet forums and blog comments, you look at summits and podcasts in our entire field, you can see that there's still a lot of questions about SIBO and misunderstanding and things that we really need to figure out in order to be able to appropriately diagnose and treat this condition. I think the best way to dive into this is just to say that I've started to doubt many of the standard assumptions or beliefs around SIBO that many of you are probably already aware of. I just want to go through five or six of these assumptions and tell you what my current thinking about them is, and this might be a little bit of a frustrating podcast to listen to because I'm not necessarily going to give you answers. I'm just going to tell you what the questions are, where my doubts are, and what further research or exploration or investigation I think we need to do.
Question #1: Is lactulose breath testing an accurate way to diagnose SIBO?
Let's start with assumption number one, which is that lactulose breath testing is an accurate way of diagnosing SIBO. As many of you know, the standard way of diagnosing SIBO in an outpatient setting is using lactulose breath testing. There is another way, which is an endoscopy, where they put a tube down your throat and take a sample of bacteria from your small intestine, but that's never used in outpatient settings because it's invasive and expensive. It's just not done. There are actually a lot of problems with that method as well, which leads us to probably the biggest issue of all from a 30,000-foot-view perspective with SIBO, is that in order for a test to be accurate, it needs to be validated against something that's a gold standard, and we have no gold standard way of diagnosing SIBO. The endoscopy, which I just mentioned, has been used as the gold standard test against which breath testing is validated. But what if the gold standard test itself is not accurate? That obviously creates some pretty big problems in terms of developing another test like breath testing and then validating it against a test that itself is not very valid. That's the biggest issue.
The problems with SIBO diagnosis and treatment
I'm not going to go into all the nitty-gritty details on why breath testing isn't necessarily as accurate as some people may believe. But in this context, I'll just say that—and this is a guess, I haven't done any rigorous study—but I would estimate that over 90 percent of the patients we test for SIBO test positive. Now this is using the former criteria and I'll come back to this in a second, but if you just use the machine-generated criteria that are printed on any of the SIBO breath testing labs, I would say over 90 percent of our patients test positive. Now, that alone should be a red flag. When more than 90 percent of your patients test positive for a condition, that should raise some eyebrows. Certainly SIBO is common, but do we really expect that 90 percent of patients, even people who are sick and dealing with chronic health issues have SIBO? I've never seen any research suggesting that over 90 percent of people with any particular conditions also have SIBO. The exception might be acne rosacea. I think I saw one study of 42 patients where 100 percent of patients with acne rosacea had SIBO [Correction: study I was referring to found that SIBO was 17 times more prevalent in patients with rosacea than in controls.] This doesn't mean for sure that the test is inaccurate, but it definitely raises my eyebrows. It makes me wonder whether we're over-diagnosing SIBO. Changes in criteria Now I mentioned the criteria, so up until pretty recently the idea was that if you see an increase in 20 parts per million or more of hydrogen in the first 120 minutes of the test, that would indicate a positive result, and the criteria were an increase in 12 parts per million for methane, but those criteria recently changed; there was a consensus statement issued in the spring. A bunch of SIBO experts got together and talked about how to update the breath-testing criteria to make it more accurate and ensure that the criteria were modified to, on the one hand with hydrogen, the changes would lead to fewer diagnoses, less overdiagnosis of hydrogen-predominant SIBO. But in the case of methane, they're going to lead to a greater number of diagnoses because those criteria, instead of becoming more strict, became more liberal. The new hydrogen criteria are increasing 20 parts per million within the first 90 minutes, and then with methane, it's any value over 10 parts per million at any point during the test, including during the third hour. That’s a pretty big difference, and that's going to lead to a lot more positive results for methane. It’s also worth pointing out that there are a lot of different studies that are critical of lactulose breath testing that suggest that there is a very high potential for false positives, especially using lactulose instead of glucose. With glucose breath testing, the opposite problem is true. There's a high potential for false negatives. If there is a positive, it should be positive. But if there's a negative, you can't rule out that SIBO might be present. Again, I'm not going to go into great detail here, but let's just say that there is a lot of uncertainty about breath testing as a way of diagnosing SIBO.
Question #2: Is SIBO always pathological?
The second assumption is that SIBO is always pathological. The idea is that if SIBO is present, it's always causing the patient's problems, whatever they are, but that's not sound thinking, of course, because we know that correlation is not causation. It's possible that SIBO could be present, but it's not actually driving whatever the patient's symptoms are. We know that early studies suggested that up to 20 to 30 percent of healthy controls have SIBO but don't have symptoms. Of course, I have to offer a side note here, which is, I don't know where these studies are finding these so-called “very healthy controls with no symptoms.” I haven't met that many of those people, but let's assume that that's true. That could mean that 20 to 30 percent of the population has SIBO, but it's not causing any problems for them. In many cases, we treat SIBO, and the numbers improve, so the patient goes from being breath-test positive to breath-test negative, but their symptoms don't necessarily improve. That would suggest that maybe SIBO was present, but it wasn't causing their symptoms. It's possible that the testing is accurate as far as what it's measuring, but what we call SIBO as a condition is not always pathological. It's also possible that SIBO might be present in a patient and might be causing some issues, maybe a mild nutrient deficiency or something like that, but it's not causing the main complaints. The reason I bring this up is that I see some patients just getting hyperfocused, almost obsessed about SIBO, at the expense of everything else. And clinicians—there is that saying, “If you've got a hammer, everything looks like a nail”—I see both clinicians and patients becoming over-focused, I think, on SIBO, and the risk there is that you actually miss other pathologies or underlying mechanisms that are really actually driving the condition in those cases if we're just myopically focused on SIBO.
Question #3: Are our treatments effective?
The third assumption is that our current treatments are effective and optimal. The typical treatments for SIBO are antimicrobials. Initially, there were prescription medications. Rifaximin is the most commonly used, especially for hydrogen-predominant SIBO, and neomycin is also added at times when methane is present. Metronidazole is another medication, or Flagyl is used in some cases for treating SIBO, as well as other antibiotics, but rifaximin certainly has become the drug of choice. But then there have been some studies recently that have found that botanicals, herbs, are as effective as rifaximin treatment or even more effective and cause fewer side effects. In general, the approach is if SIBO is there, then you use antimicrobials to reduce the growth of bacteria in the small intestine. The problem with this approach is that the efficacy is often quite low. I've seen some studies that we use rifaximin individually that show as low as 40 percent efficacy. Of course, there are other studies that show higher efficacy, and then if you combine other agents in the treatment, you can make it more effective. There was one treatment where the researchers speculated that using partially hydrolyzed guar gum would improve the efficacy of rifaximin, and in fact it did. It increased it significantly. In our clinic we use a combination protocol that uses a bunch of different things together, all of which are designed to maximize the efficacy. It also depends whether it's just hydrogen alone that's high, or methane alone that's high, or both hydrogen and methane, and each of those scenarios requires a different approach. But the problem remains that efficacy is much lower than I certainly would like to see it. Not only that, in some cases, not only do patients not get better, they actually get worse after treatment. They might get worse right away or they might improve initially, but then the symptoms return and when they come back, they come back even worse. I've seen this actually happen in multiple cycles, meaning with each treatment and each return of symptoms, the symptoms get worse after each cycle, which is obviously problematic. Then there's the very high rates of recurrence for SIBO, which is related to what I just said. One study, I think, found a recurrence rate of 45 percent in patients who had been treated by rifaximin. In our practice, despite using all of the evidence-based methods and combining several different methods, we still see recurrence rates a lot higher than optimal, than I think is acceptable. That's one of the main things that has led me to question many of these beliefs and assumptions because when the treatments are not that effective and the recurrence rates are very high, then I think that something is definitely wrong.
Question #4: Is SIBO always the underlying cause?
The fourth assumption is that SIBO was always the underlying cause of a particular condition. This is somewhat related to what I mentioned earlier, but a little bit different. In functional medicine, we're always trying to get to the root of the problem, but sometimes that's easier said than done, and it can be like peeling layers of an onion back to keep going deeper to find the deepest underlying issue. If a patient has SIBO, for example, and we treat their SIBO and it doesn't go away, or maybe it does go away and it comes back, and we do that two or three times, then of course I start wondering, “All right. Well, is there some other deeper condition that is causing the SIBO?” In this case SIBO is not necessarily a cause itself, but almost a symptom of a deeper underlying problem. In my experience, those problems can be things like:
mold or chronic inflammatory response syndrome
chronic infections like tick-borne illnesses
viral reactivation
other gut infections that have escaped detection
heavy metal toxicity
other types of toxicity
mitochondrial deficiency
And a range of other problems. But the point being that in those cases, those problems are the real thing that's driving SIBO and then whatever symptoms the SIBO is causing. It’s like layers, and so you have to keep going deeper in order to identify and address those conditions, otherwise that patient is never going to get over SIBO. We’ll just keep treating it, it might improve a little bit or not, and then it just keeps coming back. Even though rifaximin and the botanicals are relatively safe compared to other antimicrobials, they're still antimicrobials, and we still want to minimize our use of them.
Question #5: Should probiotics and prebiotics be avoided during treatment?
Assumption number five is that probiotics and prebiotics should always be avoided when a patient has SIBO and shouldn't be included in treatment. I think I've discussed this before and I'm not totally sure where this belief or assumption came from. It's pretty prevalent within the mainstream SIBO community, if you want to call it that. But all of the studies that I've seen, I think, without exception, have found that when you use probiotics, either along with antibiotics or as separate distinct treatment for SIBO, they are effective. They're either effective as solo treatment, or they increase the efficacy of SIBO [treatment protocols]. Even the studies that have used probiotics have shown positive results, which might be a little counterintuitive because you would expect probiotics to feed the bacteria that are present in the small intestine. I think there are still quite a few questions here. Certainly, I have seen probiotics, and probiotics make patients with SIBO worse, but in other cases, I've seen them make patients with SIBO significantly better. We do include very specific types of probiotics and even prebiotics in our SIBO treatment protocol. We've done that for many years because of the research I've seen on this, and I do think it is effective in most cases. This sort of points to another question or concept, which historically a lot of SIBO authorities have claimed that SIBO is just really kind of a small intestine, it's not really related to the health of the large intestine or the overall gut microbiome. That doesn't make sense to me. There is a sphincter that separates the small and large intestine, but one of the prevailing theories about how SIBO got started in the first place is it’s an inappropriate transfer of bacteria from the large intestine to the small intestine. It's entirely possible, and even likely, in my opinion, that one of the predisposing factors that can lead to that translocation of bacteria from the large intestine to the small intestine is an unhealthy large intestine. It may be that that’s one of the reasons that prebiotics and probiotics work in terms of treating and even preventing recurrence of SIBO is that they help to improve the gut microbiome. That, in turn, has a sort of upstream effect on the small intestine. Really, still a lot of unanswered questions here related to probiotics and probiotics, but I've seen enough now to convince me that the dominant idea that they should always be avoided is not true.
Question #6: Does a long-term low-FODMAP diet help prevent recurrence?
Then finally, the last assumption, number six, is that a long-term low-FODMAP diet is always a good idea in order to prevent recurrence. I have discussed this and written about this before, so I'm just going to mention it briefly. But studies have shown that a long-term low-FODMAP diet can reduce the diversity and quality of beneficial bacteria in the large intestine, and for the reasons that I just mentioned, I think that that can be problematic. Even though the low-FODMAP diet can reduce symptoms, it may be setting patients up for recurrence if it's leading to undesirable changes in the beneficial bacteria in the colon. Also, there was a recent study that just came out that found that patients with IBS are often able to reintroduce certain FODMAPs without any adverse effects. This study didn't consider SIBO, but as you probably know, many patients with IBS do have SIBO. My guess is that they would have found a similar effect if they had done the study in patients that only had SIBO. It seems that even in patients who do have SIBO or IBS that reintroducing some FODMAPs not only could be potentially beneficial, but doesn't actually lead to a return of symptoms. That's what I've always encouraged my patients to do is reintroduce as many FODMAPs as they can without significant discomfort. I think that's a wise approach because we want to keep our diet as diverse as possible, and especially when it comes to fermentable fiber, it can support our beneficial gut bacteria. Okay. I'm going to stop there. As you can see again, this is a little frustrating maybe to listen to. I'll tell you that it's super frustrating for me as a clinician. This is again something I've been paying very close attention to for a long period of time, and I feel quite frustrated with the lack of answers around many of these questions. Certainly, not for lack of looking, experimenting, and exploring, but my commitment to you is that I will continue to do that. I think it's a very important starting place to just admit when we don't know the answers to these questions at least, and to lay those questions out so we can start exploring what the answers might be, and of course that is the process of science. It's not that we always have the answers and we always know what and we stop looking. Once we think we know the answers, we always question our assumptions and we continually re-evaluate them, especially in the face of evidence that contradicts our previous assumptions or beliefs. That's the true application of the scientific method in the case of healthcare. I hope that was helpful in some way. If you're a patient out there and you're frustrated with your lack of progress with SIBO, you're definitely not alone. If you're a clinician out there and you're frustrated with your lack of progress with SIBO in terms of treating patients, you're definitely not alone. I think we should ... we need to get these questions out there more so that we can all work together to answer them. Okay, that's it for now. Please continue to send your questions in at chriskresser.com/podcastquestion, and I'll talk to you next time. Take care, everybody. RHR: Unanswered Questions About SIBO published first on https://chriskresser.com
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VH Essentials Probiotics with Prebiotics and Cranberry is made with three types of probiotics, along with cranberry and the prebiotic ingredient, inulin for added support. Here’s a quick look at what you can expect from this product:
Lactobacillus Acidophilus Lactobacillus Rhamnosus Cranberry Powder Bacillus Coagulans Inulin
Lactobacillus Acidophilus: A strain of good bacteria used to treat diarrhea, lactose intolerance, vaginal yeast infections, indigestion, gas, urinary tract infections and more.
Lactobacillus Rhamnosus: A probiotic used to prevent the growth of harmful bacteria in the body, L. rhamnosus is thought to treat diarrhea, yeast infections, BV and a range of bowel conditions.
Bacillus Coagulans: This probiotic is thought to treat and prevent respiratory infections and boost immune system function. It may also be used to treat diarrhea.
Cranberry Powder: Some studies have shown cranberry powder to be an effective tool in preventing and treating urinary tract infections. Cranberry is thought to make it difficult for bacteria to stick to the walls in the urinary tract, preventing infections.
It might also make the urine more acidic, creating a less hospitable environment for unwanted bacteria.
Inulin: A starchy substance found in a number of foods, the digestive system cannot process inulin. Instead, inulin heads to the bowel, where good bacteria can feed on it in order to grow.
Click here to learn more about harnessing the power of herbs to get through menopause pain-free.
EDITOR’S TIP: Combine this supplement with a proven menopause pill such as Femmetrinol for better results.
VH Essentials Probiotics with Prebiotics and Cranberry Quality of Ingredients
VH Essentials Probiotics with Prebiotics and Cranberry is clearly a nutritious blend of ingredients. There’s few people out there who don’t stand to benefit from taking probiotics across all age groups and health concerns.
Aside from the benefits one can expect from taking this probiotic supplement, VH Essentials Probiotics with Prebiotics and Cranberry prebiotic and cranberry may help improve the health of the existing bacteria inside users’ bodies. For example—inulin provides a source of nourishment for good bacteria, while cranberry may make the environment more acidic, which can help get rid of bad bacteria in the body.
Cranberry doesn’t work for everyone, and there are some differing opinions within the medical community regarding its efficacy.
Still, many people swear by cranberry juice and supplements, so clearly there’s something to it.
VH Essentials Probiotics with Prebiotics and Cranberry isn’t exactly designed to function as a menopause product, but users may experience some positive effects should they opt to take this supplement alongside a traditional hormone-balancing product.
We don’t however, recommend menopausal women use this product on its own should they be experiencing an increase in UTIs, yeast infections or other vaginal concerns, as the drop off in hormone production during menopause may lead to a change in vaginal flora.
Click here to learn more about the link between menopause and a rise yeast and bacterial infections.
The Price and Quality of VH Essentials Probiotics with Prebiotics and Cranberry
VH Essentials Probiotics with Prebiotics and Cranberry is not sold directly by VH Essentials, but they do distribute their products to a wide range of retailers. Those who visit the VH Essentials site can download coupons to save on this product, as well as the others in this line of vaginal support items.
VH Essentials Probiotics with Prebiotics and Cranberry is sold through multiple channels; Amazon, Walgreens, RiteAid, Target and even eBay. The supplement typically sells for $8-10 per unit and comes in a box containing 60 capsules.
Unlike other UTI treatments, VH Essentials Probiotics with Prebiotics and Cranberry is a daily supplement for nutrition and prevention from infection. The recommended dose is two capsules per day, so the product should be equal to a one-month supply.
See the latest innovations in menopause care, as well as the tried and true remedies — click for more info.
Business of VH Essentials Probiotics with Prebiotics and Cranberry
VH Essentials Probiotics with Prebiotics and Cranberry is made by a company known as VH Essentials. Here’s a bit of background information, along with their contact details:
VH Essentials Probiotics with Prebiotics and Cranberry is featured on the company website, and comes with a comprehensive FAQ section, reviews and instructions for use.
VH Essentials is dedicated to making feminine care products, explaining in their mission statement that they’ve set out to offer women the best products for tackling the range of vaginal issues that may occur.
We like that this company is trying to destigmatize issues like UTIs or vaginal odor, and addressing these concerns without shame. They’ve also provided some good information detailing the causes of vaginal odors or imbalances—noting that things like smoking, menstruation, stress, anything—can cause things to shift.
Additionally, the site does a good job dispelling the myth the vaginal odor, discharge and other cleanliness concerns are best addressed with soaps, douches and washes.
Customer Opinions of VH Essentials Probiotics with Prebiotics and Cranberry
VH Essentials Probiotics with Prebiotics and Cranberry has mostly good reviews. Here’s a look at some of the feedback previous users posted online:
“This is a great product. All I can say is, all these positive reviews were right. No issues after a few days of use. I will definitely keep taking this game changer of a supplement.”
“Love how cheap these are and how much bang you get for your buck. I use these instead of normal probiotics and have yet to get a yeast infection. I usually get them repeatedly. Highly recommend.”
“Man, I really wanted this to work, but it gave me really painful stomach aches that just wouldn’t go away. I’m bummed because I saw all these great reviews, but I found something more agreeable.”
“Used this in the past with good results, but this time around, I noticed that it made my genitals very irritated. It wasn’t worth the pain, so I ended up throwing the rest of the bottle in the trash.”
VH Essentials Probiotics with Prebiotics and Cranberry has mostly positive reviews across the e-commerce platforms this product is sold on.
Still, there were some people who didn’t love this product for one reason or another. A few of those who complained about this product cited burning and irritation in the genital region, as well as a lack of results.
In most cases, users were happy with the effects, and planned to continue using the probiotic supplement for ongoing support.
Get the vaginal support you need — click here for the full list of the menopause products you that can transform your life.
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Conclusion – Does VH Essentials Probiotics with Prebiotics and Cranberry Work?
VH Essentials Probiotics with Prebiotics and Cranberry seems like an inexpensive probiotic with largely positive reviews. We believe that some of our readers, particularly those prone to frequent infections may benefit from using this product—but it isn’t exactly designed to provide menopausal support.
Sure, just about anybody, menopausal or not can reap some benefits by adding probiotics and prebiotics to their diet — these bacteria are great for stomach issues, preventing BV and yeast infections and keeping colds and flus at bay. Additionally, probiotics are thought to improve overall nutrient absorption from the foods we eat.
Because there’s not much that can go wrong from trying VH Essentials Probiotics with Prebiotics and Cranberry, we could see this being worth a try for menopausal women with chronic vaginal issues. But, it’s worth mentioning that frequent yeast or urinary tract infections at this stage in life may be an indirect result of a hormone imbalance — an issue worth addressing in its own.
Because of the link between hormone loss and vaginal ailments, we’d suggest visiting a doctor before attempting to treat infections at home without supervision. VH Essentials Probiotics with Prebiotics and Cranberry might be a good supplement, but it’s best to first find out what the problem is.
Femmetrinol is the most effective menopause supplement on the market. Designed to replace lost hormones, this product gives users a sense of balance, resulting in increased energy, sexual desire, reduced hot flashes and night sweats and improved moods.
Femmetrinol was designed in order to give women a safe, but potent menopause supplement without the risk of any negative side effects. Check out more details about Femmetrinol and learn how it can change your experience with menopause for the better.
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Tooth Decay in Kids: Causes and Prevention
As a parent, you want to raise a healthy child that is healthy—and that should include establishing a strong foundation of oral and dental health.
I was fortunate enough to raise three cavity-free daughters, and while you may think that being a dentist gave me an unfair advantage, that’s not the case at all. Once you know how cavities form, as well as the specific cause of cavities in babies, toddlers, and big kids, you can take a proactive approach and prevent cavity development in your own kids.
Since tooth decay can happen to any exposed tooth—even if it’s just poked through—babies as young as six months can get cavities. It’s shocking but true. And because I know you don’t want that to happen to your child, this article will provide all the information you need to understand the causes and prevention of tooth decay in kids.
How do Cavities Form?
When you eat sugary foods, processed carbs, or any other food that turns to sugar once consumed, naturally-occurring bacteria in your mouth feed on these sugars. They then form bacteria clusters, protected by a layer of plaque, that excrete highly acidic waste onto the teeth. This acid then destroys tooth enamel, causing cavities.
Cavity formation is not an instant or guaranteed process. Aside from the foods that fuel bacteria growth, there are several other factors that must align before a cavity can develop. The condition of the oral microbiome (which refers to the balance of good-to-bad bacteria in the mouth), the mouth’s pH (bad, cavity-causing bacteria love acidic conditions), and the quality of the saliva all contribute to cavities.
However, when the microbiome is balanced and you are eating the proper foods, taking the proper supplements, and avoiding or limiting acidic foods and drinks, you can prevent new cavities from ever forming. In fact, you can also naturally reverse smaller, existing cavities—no fillings needed.
But if harmful bacteria are given the ideal environment to flourish, cavities are essentially a foregone conclusion. The acids excreted by the bacteria will eat away at your teeth and, over time, expose nerves in the teeth, causing the pain and sensitivity to hot and cold that we often associate with cavities.
This is process is applicable to kids as well, so if you want to keep your child’s smile healthy and bright, it’s important to be aware of the conditions that cause cavities and do everything possible to prevent them.
Common Causes of Tooth Decay in Babies and Toddlers
I recommend that parents bring their children into the dentist at around 6 months, which is typically when their first teeth are appearing.
This may seem really early, but I suggest this approach because, unfortunately, it’s not uncommon for very young children to have cavities. According to the National Institute of Dental and Craniofacial Research, more than 27 percent of children 2 to 5 have untreated tooth decay. [1]
Here are a few of the most common causes of tooth decay in babies and toddlers:
Not brushing or wiping baby teeth
As soon as baby’s first teeth appear, you should be keeping them clean in order to prevent the formation of plaque, which can lead to decay. Before your child has a full set of teeth that requires the use of a toothbrush, you can simply wipe them with a wet washcloth. For babies, you want to wipe teeth after every feeding, as formula, and even breastmilk, tends to have a high sugar content.
Giving too many sugary drinks
As I mentioned, even breastmilk is considered sugary—and so is any other drink that’s not water. When baby is young and relying on breastmilk or formula for sustenance, it’s impossible to avoid these drinks altogether. Again, this is why I recommend being vigilant about wiping baby’s teeth after feedings.
But once the child is old enough to eat solid foods, I suggest limiting or eliminating sugary drinks altogether, including juice. Along with sugary and starchy foods, these drinks are the preferred diet of erosion-causing bacteria.
Skipping the dentist
Waiting until your child has a full set of teeth (or longer) to see the dentist can delay the development of good dental habits, while also preventing early detection of any plaque buildup. The longer plaque goes unnoticed and isn’t professionally removed, the higher the likelihood it will lead to decay.
(Additionally, waiting too long before your child’s first dental visit—or waiting too long between subsequent appointments—can trigger dental anxiety at his next visit.)
Putting children to bed with a bottle
Giving your child a bottle or sippy cup at night may help soothe him to sleep, but it can also cause major damage to his teeth. Bottles and sippy cups deposit sugars from formula, juice, and other drinks directly onto the teeth. And when that contact is prolonged while baby sleeps, it is the perfect breeding ground for bacteria and baby bottle tooth decay.
If you give your child a bottle or cup before bed, be sure to take away and clean his teeth before he falls asleep.
Tips for Preventing Tooth Decay in Babies and Toddlers
Now that we know the common causes of cavities in babies and toddlers, let’s take a look at some tips for prevention:
Gently wipe down your baby’s teeth and gums with a wet washcloth after bottle- or breastfeeding
Give your baby or toddler a few sips of water after eating or drinking to further wash away any lingering sugars in the mouth
To prevent prolonged contact of sugar on teeth, never send babies and toddlers to bed with a bottle or sippy cup
Find a pediatric dentist you like and trust, and take your child to his first dental appointment between six months and a year of age, or whenever his first tooth appears
For toddlers, make sure finger foods and meals are rich in vitamin K2, vitamin D, and the other nutrients that support dental health. Avoid processed and sugary treats, as well as too many grains and legumes, which contain phytic acid and can lead to decay.
Teach your toddler good dental hygiene habits, choosing a toothbrush designed specially for kids and helping him brush to ensure that each tooth is properly cleaned
Common Causes of Tooth Decay in Big Kids
As children grow past the baby and toddler phase, it’s still important to be vigilant about maintaining the health of their teeth, even as the causes of tooth decay began to change. Let’s take a look:
Too many high-sugar and high-carb snacks
Kids are full of energy, which means they need to refuel often. Unfortunately, they often turn to the high-sugar and high-carb foods that oral bacteria thrive on, which ultimately leads to more decay.
Poor overall diet
Teeth are designed to constantly rebuild and recover from any decay. But it’s important to be aware of the foods to eat—and the foods to avoid—to heal cavities naturally, as proper diet is the most important factor in the remineralization process.
I recommend—and personally eat—a Paleo diet that is comprised of vegetables, wild-caught fish, and grass-fed meats. This diet provides the minerals and nutrients that support remineralization while being free of the harmful foods that can make it impossible to heal cavities and prevent them from forming.
You may be surprised to know that it’s not just candy that’s a problem in kids’ diets. Crackers, pastas, breads, and even dried fruits like raisins all contain the easy-to-eat carbohydrates and sugars that cavity-causing bacteria love to eat. Even beans can contribute to cavities because they contain phytic acid, which is known to prohibit the absorption of certain nutrients and minerals (including magnesium and calcium) that teeth need in order to remineralize.
Poor brushing and flossing habits
In the grand scheme of dental health, brushing and flossing ranks much lower than proper diet in order of importance. That may be good news for kids who aren’t brushing and flossing as often as they should—but who are still eating the right foods (and avoiding the wrong ones).
Kids are kids, though, and no one’s diet is perfect. So in that case, it’s very important that kids develop proper dental hygiene habits from an early age.
Skipping the dentist’s office
As important as it is to start taking your child to the dentist early, t’s also important to keep regular appointments to make dental visits an expected, enjoyable experience. Skipping the dentist decreases the opportunities to catch plaque before it turns into something more serious and may also cause your child to dread going in the future.
Tips for Preventing Tooth Decay in Big Kids
Skip the cookies and crackers and offer kids snacks made with fruits, vegetables, and healthy fats to help them get the vitamins and minerals they need for a healthy mouth that can heal and prevent cavities.
Encourage kids to rinse their mouths with water after eating to help eliminate some of the food and sugar debris that bacteria feed on. (But avoid brushing until 30 minutes after eating, as the enamel may be more susceptible to erosion immediately after consuming highly acidic or processed foods.)
Consider kid-specific supplements, including vitamin K2 vitamin D, and oral probiotics.
Teach kids good oral hygiene habits, including flossing and proper brushing technique. This involves gently wiggling the toothbrush around the teeth, rather than using a hard, see-saw motion against the teeth and gums.
I recommend that parents brush their child’s teeth until he is mature and skilled enough to do it on his own—or at least until age 7. Try brushing your teeth in front of your kids to set a good example. You can make it a family activity that everyone participates in together by setting a timer and keeping the experience positive.
Try this recipe DIY kids toothpaste, since many toothpastes and mouthwashes for kids contain questionable ingredients like triclosan, sodium lauryl sulfate, artificial colorings, fluoride, titanium dioxide, glycerin, and abrasive ingredients. These ingredients can disrupt the mouth’s microbiome or be too harsh on teeth, which can contribute to tooth decay in kids.
Make sure your kids are sleeping well. If your kids are snoring, grinding their teeth, or even sleeping with their mouth open, it could be affecting their oral health.
When the mouth is left open during sleep, it starts to dry out, which throws off the balance of oral microbiome, allowing bad bacteria to proliferate. This type of sleep also tends to be less restful than close-mouthed sleep, and we all know how critical a good night’s sleep is. Consider mouth taping for older kids, which force nose breathing and helps keep moisture in the mouth.
Visit the dentist regularly, typically every six months. A dentist can help keep any plaque buildup under control and make sure your child’s mouth stays healthy for years to come.
Final thoughts on preventing tooth decay in kids
Many parents think that tooth decay in baby teeth isn’t a problem, as those teeth are going to fall out anyway. Unfortunately, that’s not the case. The truth is, decayed baby teeth can impact the development of adult teeth and impact your child’s oral health for years to come.
If your child develops cavities and grows accustomed to painful teeth, he might be hesitant to chew or otherwise use his mouth appropriately, which could lead to facial development issues. And if a dentist has to remove badly decayed baby teeth, it can affect cause the other baby teeth to shift to fill the empty space and may impact how the adult teeth grow in.
Luckily, cavities in kids can be prevented with the right diet, habits, lifestyle factors, and habits, and it’s important to establish them early. Creating good routines, taking the time to care for children’s teeth before they can do it themselves, scheduling a routine visit with your children’s dentist and focusing on a nourishing diet can make a huge difference in preventing tooth decay in kids. Your child’s smile is precious. It’s important to keep it healthy, too.
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A sex doll for women’s health: dildo designer talks the euphorium of conception
Stephanie Berman is among a developing number of entrepreneurs investigating new technologies for a market that is no longer taboo
Stephanie Berman is sitting on the terrace of the Hilton hotel near Hollywood in the hazy January sunshine, and maintaining a bright pink dildo.
Its not just any dildo this is the latest version of Bermans inseminating invention, the Semenette , now with strap-on alternative, new qualities and renamed the POP.
Squeezing a small run at the end of the suction tube that runs through it, she dips the hanging gratuity into a bottle of( on this moment) ocean and draws up the fluid. With a flourish she accommodates it aloft, crushes the run and whoosh an arc of irrigate spurts over the counter.
Its a fornication toy with a functional determination who are interested in womens health concerns, shows Berman, otherwise known as Spermin Berman, who proudly adds that she and her wife saw their daughter , now two, on the first strive and have a second child on the way. Berman is in Hollywood at She, the Sexual Health Expo, to promote the new design.
It makes pleasure to something that are able to stressful, says Berman of the struggle to design. She and her spouse, a coach, had tried the conventional goose baster insemination procedure. Guess me there is nothing sexy in that.
Organised by adult publisher XBIZ, the She pact has a relax, educational flavor to take in order to realize visitors detect comfy. Neighbourhood paralegal Katie Frame has come with her friend Kirsti Olson. I came believing it would be hypersexual and porn-esque. But its really comfortable and positive, say Frame. Theres a lot about women and empowerment.
Stephanie Berman expresses the Semenette POP, an insemination design which, she says, facilitated her wife conceive Photograph: Emily Berl for the Guardian
Talks have included Aging& Sex by generator Lynn Brown Rosenberg, author of My Sexual Awakening at 70 and whose upcoming bookings include a talk to Mensa members and Role Play With Koko.
Sex toys have lost much of their taboo
Berman is just one entrepreneur inquiring more sophisticated manufacturing the procedure and new technologies for a copulation toy marketplace that has lost much of its taboo. Boundaries between adult makes and sex health commodities are blurring and, as the She episode substantiates, theres now a wide array of well-designed, high-end products made from medical or food-grade plastics and silicones.
Theres a real change, with people are now beginning to challenge high-quality products, she says. No one wants to put toxic substance into their body. Shes referring to phthalates, a widely used chemical group that constructs plastics flexible and has been used in sex toys.
Add to that the growth of internet-connected smart sex machines that are becoming increasingly mainstream; the award for digital health and fitness at Januarys influential Consumer Electronics Show in Las Vegas departed, for the first time, to sex toy fellowship OhMiBod. Its insertable Lovelife Krush device for monitoring the effectiveness of pelvic floor exercises labours via bluetooth with a smartphone app that contributes visual and vibratory feedback. It predicts, the company states, that stronger muscles will help prevent incontinence and deliver better orgasms. It will sell for $129 when it goes on sale in the spring.
No one in service industries ever triumphed before its about as mainstream[ an honor] as you can get, says Michael Guilfoyle, business manager of light-headed bedroom servitude corporation Sportsheets. This used to be an industry you shunned as an entrepreneur. But now its no longer porn-associated, theres a new generation in the business. He points to the status of women in a crispy pitch-black clothing working on the We-Vibe stand. That lady speaks 10 languages.
Back in the She occasion, Berman is holding forth to a rapt audience with her scheduled talk, Sex Toys: Beyond the Orgasm. Berman activities a positive , no-nonsense vibe, substantiating various categories of sex toys as though it were state-of-the artistry kitchen gadgets.
The Pulse by Hot Octopus, a sort of vibrating stimulator for men, is great for men with erectile dysfunction or disabilities, she says, while her own POP device is designed for same-sex duets to supersede more banal methods of conceiving using donated seman. Another is the Candy, a small, blush-pink dance with a loop were prepared by Chinese engineers for pelvic floor exercises.
Berman, 34, grew up in a outskirt of Boston, investigated English and sociology and wanted to be a professional lyricist. But in 2001 she ended up in the business her baby started, Sepal Reproductive, a manufacturer of catheters for IVF procedures and distributor of diagnostic tests and medical devices. Our neighbours thought we led a sperm bank, says Berman, who started as a sales rep and is now its vice president.
Berman was developing a home insemination paraphernalium in 2009 when she came up with the idea for the Semenette, launched in 2012 by her own fellowship Berman Innovations. The first version was like a medical machine, make use of hard silicone and offered in three flesh tones. For the second machine put in place in late 2015, Berman partnered with a high-end German sex-toy busines announced Fun Factory.
Sarah Tomchesson is head of business operations for US adult retail store The Pleasure Chest, which exchanges the Semenette, but also says she saw utilizing the first form. Its very exciting to have something to employ that allows you to keep more intimacy. The orgasmic process is integral to success in getting pregnant, adds Tomchesson, who now has an eight-month old-fashioned daughter with her partner.
She thinks it will be easier for Semenette to market itself as a sexuality doll than as a fertility invention a highly lucrative and more competitive sphere. The exchange of views among seman is regulated by the FDA at a doctors facility and there is a lot of indebtednes. You will run into doctors who are very resistant to talk about home insemination.
Insemination is a recession-proof business
Semenettes website also explains how the POP is appealing to other communities, including female-to-male transgender clients. Berman has sold at least 500 of the brand-new inventions both to retailers and individuals mostly in the US, Canada and the UK. Its gaining traction in the fetish and kink-play domain and more gentlemen are telling, including people with physical disabilities like muscular skeletal disease, she says.
Bermans product likewise comes with a strap-on option called the Joque Harness for $119.95, and while at a recent porn manufacture phenomenon in Las Vegas, she spoke on a board that included a disabled person and a plus-size talker. The adult manufacture is more aware of other gatherings. You have to think outside the box and not target a cookie-cutter clientele.
Its a slump proof business because everyone wants newborns, says Berman. Semenettes device retails at $139.95, compared to the average $500 to $1,500 cost of one see to a doctors role for intrauterine insemination. And in the US, health insurance normally merely knocks in after six visits, she says.
After Bermans talk, a patently dressed Chinese business wife approaches Berman and misses a private join. Minnie Zhang, co-founder of brand-new Shanghai-based sex doll busines Magic Motion, ponders Berman can help them steer the American sell.
She plucks a elegant booklet out of her bag detailing luxurious makes such as the Magic Motion Flamingo, a wearable smart vibrator made of liquid silicone. Ten years ago Chinese parties didnt is well known pattern and simply imitated[ everything ], says Zhang. Now with a younger, more affluent and sexually open generation, Chinese corporations are beginning to apply their motif savvy and technical science into copulation dolls. Its a huge market, says Zhang, whose corporation has around 30 hires working on apps alone and hopes to counter the countrys honour as a producer of inexpensive, low-grade fornication toys.
Its a work of art
IMTOY co-founder Johnny Jiang, who has a degree in opto-electronics from Liverpool University, is also substantiating the companys new men vibrator, the Piu. A stylish pitch-black and ruby-red device slightly larger than, well, a hand, the $200 Piu is boxed like an expensive bottle of perfume.
OMTOY, the company behind Pui, has a unit of video creators in Japan making adult content for the Pui app. There are 30 tremor blueprints and three machines, to give a soothing butterfly flutter or a big thumping, von Abo explains.
Annie Kim, federal employees at the company IMTOY, evidences off the Piu, an interactive masturbation toy for men Photograph: Emily Berl for the Guardian
IMTOY likewise does the Candy, a small blush-pink ball that contains a sensor and is designed for checking pelvic floor exercises. Its a work of art, says Jiang, pointing to a design resting on a wireless charger, which also has an ultraviolet transmitter that sterilizes it when the case is covered; ultraviolet can kill 270 the different types of bacteria, the company claims.
Marketing director Matthew von Abo makes a Candy in my hand and syncs it via bluetooth to the app on his iPhone. It hums and shakes gently and when I crush it, the pressure sensor inside triggers a number on the app. I squeeze harder and the number rises from 100 to 225. You can do a different exercising each day, he excuses. Hold for three seconds, relax for five, echo 70 times.
Meanwhile Berman is preparing to head off to a porn convention before she moves home to their own families in Boston. Does she ever think about what she and her bride will tell their children about their idea?
Weve “was talkin about a” it. I will tell them that their mommy fabricated something that( was used) in a loving, intimate behavior. I wont go into all the gory details. And when theyre teenagers? I havent had considered that far ahead yet.
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A sex doll for women’s health: dildo designer talks the euphorium of conception
Stephanie Berman is among a developing number of entrepreneurs investigating new technologies for a market that is no longer taboo
Stephanie Berman is sitting on the terrace of the Hilton hotel near Hollywood in the hazy January sunshine, and maintaining a bright pink dildo.
Its not just any dildo this is the latest version of Bermans inseminating invention, the Semenette , now with strap-on alternative, new qualities and renamed the POP.
Squeezing a small run at the end of the suction tube that runs through it, she dips the hanging gratuity into a bottle of( on this moment) ocean and draws up the fluid. With a flourish she accommodates it aloft, crushes the run and whoosh an arc of irrigate spurts over the counter.
Its a fornication toy with a functional determination who are interested in womens health concerns, shows Berman, otherwise known as Spermin Berman, who proudly adds that she and her wife saw their daughter , now two, on the first strive and have a second child on the way. Berman is in Hollywood at She, the Sexual Health Expo, to promote the new design.
It makes pleasure to something that are able to stressful, says Berman of the struggle to design. She and her spouse, a coach, had tried the conventional goose baster insemination procedure. Guess me there is nothing sexy in that.
Organised by adult publisher XBIZ, the She pact has a relax, educational flavor to take in order to realize visitors detect comfy. Neighbourhood paralegal Katie Frame has come with her friend Kirsti Olson. I came believing it would be hypersexual and porn-esque. But its really comfortable and positive, say Frame. Theres a lot about women and empowerment.
Stephanie Berman expresses the Semenette POP, an insemination design which, she says, facilitated her wife conceive Photograph: Emily Berl for the Guardian
Talks have included Aging& Sex by generator Lynn Brown Rosenberg, author of My Sexual Awakening at 70 and whose upcoming bookings include a talk to Mensa members and Role Play With Koko.
Sex toys have lost much of their taboo
Berman is just one entrepreneur inquiring more sophisticated manufacturing the procedure and new technologies for a copulation toy marketplace that has lost much of its taboo. Boundaries between adult makes and sex health commodities are blurring and, as the She episode substantiates, theres now a wide array of well-designed, high-end products made from medical or food-grade plastics and silicones.
Theres a real change, with people are now beginning to challenge high-quality products, she says. No one wants to put toxic substance into their body. Shes referring to phthalates, a widely used chemical group that constructs plastics flexible and has been used in sex toys.
Add to that the growth of internet-connected smart sex machines that are becoming increasingly mainstream; the award for digital health and fitness at Januarys influential Consumer Electronics Show in Las Vegas departed, for the first time, to sex toy fellowship OhMiBod. Its insertable Lovelife Krush device for monitoring the effectiveness of pelvic floor exercises labours via bluetooth with a smartphone app that contributes visual and vibratory feedback. It predicts, the company states, that stronger muscles will help prevent incontinence and deliver better orgasms. It will sell for $129 when it goes on sale in the spring.
No one in service industries ever triumphed before its about as mainstream[ an honor] as you can get, says Michael Guilfoyle, business manager of light-headed bedroom servitude corporation Sportsheets. This used to be an industry you shunned as an entrepreneur. But now its no longer porn-associated, theres a new generation in the business. He points to the status of women in a crispy pitch-black clothing working on the We-Vibe stand. That lady speaks 10 languages.
Back in the She occasion, Berman is holding forth to a rapt audience with her scheduled talk, Sex Toys: Beyond the Orgasm. Berman activities a positive , no-nonsense vibe, substantiating various categories of sex toys as though it were state-of-the artistry kitchen gadgets.
The Pulse by Hot Octopus, a sort of vibrating stimulator for men, is great for men with erectile dysfunction or disabilities, she says, while her own POP device is designed for same-sex duets to supersede more banal methods of conceiving using donated seman. Another is the Candy, a small, blush-pink dance with a loop were prepared by Chinese engineers for pelvic floor exercises.
Berman, 34, grew up in a outskirt of Boston, investigated English and sociology and wanted to be a professional lyricist. But in 2001 she ended up in the business her baby started, Sepal Reproductive, a manufacturer of catheters for IVF procedures and distributor of diagnostic tests and medical devices. Our neighbours thought we led a sperm bank, says Berman, who started as a sales rep and is now its vice president.
Berman was developing a home insemination paraphernalium in 2009 when she came up with the idea for the Semenette, launched in 2012 by her own fellowship Berman Innovations. The first version was like a medical machine, make use of hard silicone and offered in three flesh tones. For the second machine put in place in late 2015, Berman partnered with a high-end German sex-toy busines announced Fun Factory.
Sarah Tomchesson is head of business operations for US adult retail store The Pleasure Chest, which exchanges the Semenette, but also says she saw utilizing the first form. Its very exciting to have something to employ that allows you to keep more intimacy. The orgasmic process is integral to success in getting pregnant, adds Tomchesson, who now has an eight-month old-fashioned daughter with her partner.
She thinks it will be easier for Semenette to market itself as a sexuality doll than as a fertility invention a highly lucrative and more competitive sphere. The exchange of views among seman is regulated by the FDA at a doctors facility and there is a lot of indebtednes. You will run into doctors who are very resistant to talk about home insemination.
Insemination is a recession-proof business
Semenettes website also explains how the POP is appealing to other communities, including female-to-male transgender clients. Berman has sold at least 500 of the brand-new inventions both to retailers and individuals mostly in the US, Canada and the UK. Its gaining traction in the fetish and kink-play domain and more gentlemen are telling, including people with physical disabilities like muscular skeletal disease, she says.
Bermans product likewise comes with a strap-on option called the Joque Harness for $119.95, and while at a recent porn manufacture phenomenon in Las Vegas, she spoke on a board that included a disabled person and a plus-size talker. The adult manufacture is more aware of other gatherings. You have to think outside the box and not target a cookie-cutter clientele.
Its a slump proof business because everyone wants newborns, says Berman. Semenettes device retails at $139.95, compared to the average $500 to $1,500 cost of one see to a doctors role for intrauterine insemination. And in the US, health insurance normally merely knocks in after six visits, she says.
After Bermans talk, a patently dressed Chinese business wife approaches Berman and misses a private join. Minnie Zhang, co-founder of brand-new Shanghai-based sex doll busines Magic Motion, ponders Berman can help them steer the American sell.
She plucks a elegant booklet out of her bag detailing luxurious makes such as the Magic Motion Flamingo, a wearable smart vibrator made of liquid silicone. Ten years ago Chinese parties didnt is well known pattern and simply imitated[ everything ], says Zhang. Now with a younger, more affluent and sexually open generation, Chinese corporations are beginning to apply their motif savvy and technical science into copulation dolls. Its a huge market, says Zhang, whose corporation has around 30 hires working on apps alone and hopes to counter the countrys honour as a producer of inexpensive, low-grade fornication toys.
Its a work of art
IMTOY co-founder Johnny Jiang, who has a degree in opto-electronics from Liverpool University, is also substantiating the companys new men vibrator, the Piu. A stylish pitch-black and ruby-red device slightly larger than, well, a hand, the $200 Piu is boxed like an expensive bottle of perfume.
OMTOY, the company behind Pui, has a unit of video creators in Japan making adult content for the Pui app. There are 30 tremor blueprints and three machines, to give a soothing butterfly flutter or a big thumping, von Abo explains.
Annie Kim, federal employees at the company IMTOY, evidences off the Piu, an interactive masturbation toy for men Photograph: Emily Berl for the Guardian
IMTOY likewise does the Candy, a small blush-pink ball that contains a sensor and is designed for checking pelvic floor exercises. Its a work of art, says Jiang, pointing to a design resting on a wireless charger, which also has an ultraviolet transmitter that sterilizes it when the case is covered; ultraviolet can kill 270 the different types of bacteria, the company claims.
Marketing director Matthew von Abo makes a Candy in my hand and syncs it via bluetooth to the app on his iPhone. It hums and shakes gently and when I crush it, the pressure sensor inside triggers a number on the app. I squeeze harder and the number rises from 100 to 225. You can do a different exercising each day, he excuses. Hold for three seconds, relax for five, echo 70 times.
Meanwhile Berman is preparing to head off to a porn convention before she moves home to their own families in Boston. Does she ever think about what she and her bride will tell their children about their idea?
Weve “was talkin about a” it. I will tell them that their mommy fabricated something that( was used) in a loving, intimate behavior. I wont go into all the gory details. And when theyre teenagers? I havent had considered that far ahead yet.
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