#illinois institute of technology

[materialsscienceandengineering]

A paper recently published in Nature Energy based on pioneering research done at Illinois Institute of Technology reveals a promising breakthrough in green energy: an electrolyzer device capable of converting carbon dioxide into propane in a manner that is both scalable and economically viable. As the United States races toward its target of net-zero greenhouse gas emissions by 2050, innovative methods to reduce the significant carbon dioxide emissions from electric power and industrial sectors are critical. Mohammad Asadi, assistant professor of chemical engineering at Illinois Tech, spearheaded this groundbreaking research. "Making renewable chemical manufacturing is really important," says Asadi. "It's the best way to close the carbon cycle without losing the chemicals we currently use daily." What sets Asadi's electrolyzer apart is its unique catalytic system. It uses inexpensive, readily available materials to produce tri-carbon molecules -- fundamental building blocks for fuels like propane, which is used for purposes ranging from home heating to aviation.

Read more.

[germanpostwarmodern]

Crown Hall (1950-56) of Illinois Institute of Technology in Chicago, IL, USA, by Mies van der Rohe. Photo by Balthazar Korab.

[transit-fag]

So I am still working on my master post on urban design education in the US but here are the schools with masters programs that I have found so far

University of Kentucky

University of Illinois Chicago

University of Washington

Georgia Tech

UNC Charlotte

University of Cincinnati

New York Institute of Technology

Miami

Colorado Denver

Harvard

Carnegie Mellon

Clemson

University of Virginia

Kent State

University of South Florida

University of Georgia

UC Berkeley

University of Illinois Urbana-Champaign

Michigan

Thomas Jefferson University

UPenn

UT Austin

Ball State

New Jersey Institute of Technology

Iowa State

[liberalsarecool]

25 years of 'thoughts and prayers'.

Thurston High School

Columbine High School

Heritage High School

Deming Middle School

Fort Gibson Middle School

Buell Elementary School

Lake Worth Middle School

University of Arkansas

Junipero Serra High School

Santana High School

Bishop Neumann High School

Pacific Lutheran University

Granite Hills High School

Lew Wallace High School

Martin Luther King, Jr High School

Appalachian School of Law

Washington High School

Conception Abbey

Benjamin Tasker Middle School

University of Arizona

Lincoln High School

John McDonogh High School

Red Lion Area Junior High School

Case Western Reserve University

Rocori High School

Ballou High School

Randallstown High School

Bowen High School

Red Lake Senior High School

Harlan Community Academy High School

Campbell County High School

Milwee Middle School

Roseburg High School

Pine Middle School

Essex Elementary School

Duquesne University

Platte Canyon High School

Weston High School

West Nickel Mines School

Joplin Memorial Middle School

Henry Foss High School

Compton Centennial High School

Virginia Tech

Success Tech Academy

Miami Carol City Senior High School

Hamilton High School

Louisiana Technical College

Mitchell High School

EO Green Junior High School

Northern Illinois University

Lakota Middle School

Knoxville Central High School

Willoughby South High School

Henry Ford High School

University of Central Arkansas

Dillard High School

Dunbar High School

Hampton University

Harvard College

Larose-Cut Off Middle School

International Studies Academy

Skyline College

Discovery Middle School

University of Alabama

DeKalb School

Deer Creek Middle School

Ohio State University

Mumford High School

University of Texas

Kelly Elementary School

Marinette High School

Aurora Central High School

Millard South High School

Martinsville West Middle School

Worthing High School

Millard South High School

Highlands Intermediate School

Cape Fear High School

Chardon High School

Episcopal School of Jacksonville

Oikos University

Hamilton High School

Perry Hall School

Normal Community High School

University of South Alabama

Banner Academy South

University of Southern California

Sandy Hook Elementary School

Apostolic Revival Center Christian School

Taft Union High School

Osborn High School

Stevens Institute of Business and Arts

Hazard Community and Technical College

Chicago State University

Lone Star College-North

Cesar Chavez High School

Price Middle School

University of Central Florida

New River Community College

Grambling State University

Massachusetts Institute of Technology

Ossie Ware Mitchell Middle School

Ronald E McNair Discovery Academy

North Panola High School

Carver High School

Agape Christian Academy

Sparks Middle School

North Carolina A&T State University

Stephenson High School

Brashear High School

West Orange High School

Arapahoe High School

Edison High School

Liberty Technology Magnet High School

Hillhouse High School

Berrendo Middle School

Purdue University

South Carolina State University

Los Angeles Valley College

Charles F Brush High School

University of Southern California

Georgia Regents University

Academy of Knowledge Preschool

Benjamin Banneker High School

D H Conley High School

East English Village Preparatory Academy

Paine College

Georgia Gwinnett College

John F Kennedy High School

Seattle Pacific University

Reynolds High School

Indiana State University

Albemarle High School

Fern Creek Traditional High School

Langston Hughes High School

Marysville Pilchuck High School

Florida State University

Miami Carol City High School

Rogers State University

Rosemary Anderson High School

Wisconsin Lutheran High School

Frederick High School

Tenaya Middle School

Bethune-Cookman University

Pershing Elementary School

Wayne Community College

JB Martin Middle School

Southwestern Classical Academy

Savannah State University

Harrisburg High School

Umpqua Community College

Northern Arizona University

Texas Southern University

Tennessee State University

Winston-Salem State University

Mojave High School

Lawrence Central High School

Franklin High School

Muskegon Heights High School

Independence High School

Madison High School

Antigo High School

University of California-Los Angeles

Jeremiah Burke High School

Alpine High School

Townville Elementary School

Vigor High School

Linden McKinley STEM Academy

June Jordan High School for Equity

Union Middle School

Mueller Park Junior High School

West Liberty-Salem High School

University of Washington

King City High School

North Park Elementary School

North Lake College

Freeman High School

Mattoon High School

Rancho Tehama Elementary School

Aztec High School

Wake Forest University

Italy High School

NET Charter High School

Marshall County High School

Sal Castro Middle School

Marjory Stoneman Douglas High School

Great Mills High School

Central Michigan University

Huffman High School

Frederick Douglass High School

Forest High School

Highland High School

Dixon High School

Santa Fe High School

Noblesville West Middle School

University of North Carolina Charlotte

STEM School Highlands Ranch

Edgewood High School

Palm Beach Central High School

Providence Career & Technical Academy

Fairley High School (school bus)

Canyon Springs High School

Dennis Intermediate School

Florida International University

Central Elementary School

Cascade Middle School

Davidson High School

Prairie View A & M University

Altascocita High School

Central Academy of Excellence

Cleveland High School

Robert E Lee High School

Cheyenne South High School

Grambling State University

Blountsville Elementary School

Holmes County, Mississippi (school bus)

Prescott High School

College of the Mainland

Wynbrooke Elementary School

UNC Charlotte

Riverview Florida (school bus)

Second Chance High School

Carman-Ainsworth High School

Williwaw Elementary School

Monroe Clark Middle School

Central Catholic High School

Jeanette High School

Eastern Hills High School

DeAnza High School

Ridgway High School

Reginald F Lewis High School

Saugus High School

Pleasantville High School

Waukesha South High School

Oshkosh High School

Catholic Academy of New Haven

Bellaire High School

North Crowley High School

McAuliffe Elementary School

South Oak Cliff High School

Texas A&M University-Commerce

Sonora High School

Western Illinois University

Oxford High School

Robb Elementary SchoolThurston High School

Columbine High School

Heritage High School

Deming Middle School

Fort Gibson Middle School

Buell Elementary School

Lake Worth Middle School

University of Arkansas

Junipero Serra High School

Santana High School

Bishop Neumann High School

Pacific Lutheran University

Granite Hills High School

Lew Wallace High School

Martin Luther King, Jr High School

Appalachian School of Law

Washington High School

Conception Abbey

Benjamin Tasker Middle School

University of Arizona

Lincoln High School

John McDonogh High School

Red Lion Area Junior High School

Case Western Reserve University

Rocori High School

Ballou High School

Randallstown High School

Bowen High School

Red Lake Senior High School

Harlan Community Academy High School

Campbell County High School

Milwee Middle School

Roseburg High School

Pine Middle School

Essex Elementary School

Duquesne University

Platte Canyon High School

Weston High School

West Nickel Mines School

Joplin Memorial Middle School

Henry Foss High School

Compton Centennial High School

Virginia Tech

Success Tech Academy

Miami Carol City Senior High School

Hamilton High School

Louisiana Technical College

Mitchell High School

EO Green Junior High School

Northern Illinois University

Lakota Middle School

Knoxville Central High School

Willoughby South High School

Henry Ford High School

University of Central Arkansas

Dillard High School

Dunbar High School

Hampton University

Harvard College

Larose-Cut Off Middle School

International Studies Academy

Skyline College

Discovery Middle School

University of Alabama

DeKalb School

Deer Creek Middle School

Ohio State University

Mumford High School

University of Texas

Kelly Elementary School

Marinette High School

Aurora Central High School

Millard South High School

Martinsville West Middle School

Worthing High School

Millard South High School

Highlands Intermediate School

Cape Fear High School

Chardon High School

Episcopal School of Jacksonville

Oikos University

Hamilton High School

Perry Hall School

Normal Community High School

University of South Alabama

Banner Academy South

University of Southern California

Sandy Hook Elementary School

Apostolic Revival Center Christian School

Taft Union High School

Osborn High School

Stevens Institute of Business and Arts

Hazard Community and Technical College

Chicago State University

Lone Star College-North

Cesar Chavez High School

Price Middle School

University of Central Florida

New River Community College

Grambling State University

Massachusetts Institute of Technology

Ossie Ware Mitchell Middle School

Ronald E McNair Discovery Academy

North Panola High School

Carver High School

Agape Christian Academy

Sparks Middle School

North Carolina A&T State University

Stephenson High School

Brashear High School

West Orange High School

Arapahoe High School

Edison High School

Liberty Technology Magnet High School

Hillhouse High School

Berrendo Middle School

Purdue University

South Carolina State University

Los Angeles Valley College

Charles F Brush High School

University of Southern California

Georgia Regents University

Academy of Knowledge Preschool

Benjamin Banneker High School

D H Conley High School

East English Village Preparatory Academy

Paine College

Georgia Gwinnett College

John F Kennedy High School

Seattle Pacific University

Reynolds High School

Indiana State University

Albemarle High School

Fern Creek Traditional High School

Langston Hughes High School

Marysville Pilchuck High School

Florida State University

Miami Carol City High School

Rogers State University

Rosemary Anderson High School

Wisconsin Lutheran High School

Frederick High School

Tenaya Middle School

Bethune-Cookman University

Pershing Elementary School

Wayne Community College

JB Martin Middle School

Southwestern Classical Academy

Savannah State University

Harrisburg High School

Umpqua Community College

Northern Arizona University

Texas Southern University

Tennessee State University

Winston-Salem State University

Mojave High School

Lawrence Central High School

Franklin High School

Muskegon Heights High School

Independence High School

Madison High School

Antigo High School

University of California-Los Angeles

Jeremiah Burke High School

Alpine High School

Townville Elementary School

Vigor High School

Linden McKinley STEM Academy

June Jordan High School for Equity

Union Middle School

Mueller Park Junior High School

West Liberty-Salem High School

University of Washington

King City High School

North Park Elementary School

North Lake College

Freeman High School

Mattoon High School

Rancho Tehama Elementary School

Aztec High School

Wake Forest University

Italy High School

NET Charter High School

Marshall County High School

Sal Castro Middle School

Marjory Stoneman Douglas High School

Great Mills High School

Central Michigan University

Huffman High School

Frederick Douglass High School

Forest High School

Highland High School

Dixon High School

Santa Fe High School

Noblesville West Middle School

University of North Carolina Charlotte

STEM School Highlands Ranch

Edgewood High School

Palm Beach Central High School

Providence Career & Technical Academy

Fairley High School (school bus)

Canyon Springs High School

Dennis Intermediate School

Florida International University

Central Elementary School

Cascade Middle School

Davidson High School

Prairie View A & M University

Altascocita High School

Central Academy of Excellence

Cleveland High School

Robert E Lee High School

Cheyenne South High School

Grambling State University

Blountsville Elementary School

Holmes County, Mississippi (school bus)

Prescott High School

College of the Mainland

Wynbrooke Elementary School

UNC Charlotte

Riverview Florida (school bus)

Second Chance High School

Carman-Ainsworth High School

Williwaw Elementary School

Monroe Clark Middle School

Central Catholic High School

Jeanette High School

Eastern Hills High School

DeAnza High School

Ridgway High School

Reginald F Lewis High School

Saugus High School

Pleasantville High School

Waukesha South High School

Oshkosh High School

Catholic Academy of New Haven

Bellaire High School

North Crowley High School

McAuliffe Elementary School

South Oak Cliff High School

Texas A&M University-Commerce

Sonora High School

Western Illinois University

Oxford High School

Bridgewater University

Robb Elementary School

Michigan State University

Covenant Christian School

.

TBA

***feel free to copy and paste, then share ****

[huriya]

College Shitlist (boycott these colleges)

This is the updating list of colleges where pro-palestine protests are present that have brutalized/arrested/punished their students for protesting the ongoing palestinian genocide.

REMEMBER: DO NOT GIVE YOUR MONEY TO THESE COLLEGES. PROTESTS ON THESE CAMPUSES ARE IMPORTANT, BUT KEEPING YOUR INTELLIGENCE AND MONEY AWAY FROM THESE ABHORRENT INSTITUTIONS DIMINISHES THEIR POWER. THEIR ONLY POWER COMES FROM THEIR STUDENTS AND THEIR MONEY. YOU HAVE THE POWER TO TAKE THEIR PRESTIGE AWAY.

In No Particular Order:

Princeton University

Massachusetts Institute of Technology

University of California - Berkeley

Stanford University

Virginia Tech

University of Michigan - Ann Arbor

University of Washington

University of Minnesota - Twin Cities

University of Wisconsin - Madison

Harvard University

Yale University

University of California - Los Angeles

Cornell University

University of Pittsburgh

University of Chicago

University of Southern California

University of California - San Diego

Tufts University

Northeastern University

Stony Brook University

University of Connecticut

University of California - Merced

University of Massachusetts - Amherst

University of Iowa

University of Arizona

Arizona State University

University of California - Irvine

George Washington University

DePaul University

University of Pennsylvania

Pomona College

University of Texas - Dallas

The New School

University of Houston

University of Rochester

University of New Mexico

Duke University

New York University

University of North Carolina - Chapel Hill

Barnards College

University of Vanderbilt

Rutgers University - New Brunswick

Columbia University

Portland State University

University of Oregon

California Polytechnic Institute Humboldt

California Polytechnic University - San Luis Obispo

Northern Arizona University

University of Utah

University of Kansas

University of Illinois - Urbana Champaign

Washington University

New Mexico State University

University of Texas - Austin

Tulane University

University of South Florida

University of North Florida

University of Florida

Emory University

University of Georgia

Mercer University

Notre Dame University

Case Western Reserve University

The Ohio State University

Virginian Commonwealth University

University of Virginia

University of Buffalo

State University of New York - Purchase

State University of New York - New Paltz

Brown University

Brandeis University

Dartmouth College

University of New Hampshire

Emerson College

CUNY City College of New York

International List:

University of Amsterdam

University of Alberta

University of Queensland

University of Sydney

University of Melbourne

Australian National University

University of New South Wales

University of Calgary

University of Oxford

Feel free to share this list, send me additional colleges to add (WITH SOURCES), and/or request more information on a particular college

[mindblowingscience]

Inspired by the color-changing ability of chameleons, researchers have developed a sustainable technique to 3D-print multiple, dynamic colors from a single ink. "By designing new chemistries and printing processes, we can modulate structural color on the fly to produce color gradients not possible before," said Ying Diao, an associate professor of chemistry and chemical and biomolecular engineering at the University of Illinois Urbana-Champaign and a researcher at the Beckman Institute for Advanced Science and Technology. The study appears in the journal PNAS.

Continue Reading.

[paullorenz]

I am very happy to have new representation in Chicago! Please visit Alma Art and Interiors!

[moneeb0930]

𝗦𝗛𝗜𝗥𝗟𝗘𝗬 𝗔𝗡𝗡 𝗝𝗔𝗖𝗞𝗦𝗢𝗡 (1946- )

Shirley Ann Jackson, born in 1946 in Washington, D.C., has achieved numerous firsts for African American women. She was the first black woman to earn a Ph.D. from Massachusetts Institute of Technology (M.I.T.); to receive a Ph.D. in theoretical solid state physics; to be elected president and then chairman of the board of the American Association for the Advancement of Science (AAAS); to be president of a major research university, Rensselaer Polytechnic Institute in New York; and to be elected to the National Academy of Engineering. Jackson was also both the first African American and the first woman to chair the U.S. Nuclear Regulatory Commission.

Jackson’s parents and teachers recognized her natural talent for science and nurtured her interest from a young age. In 1964, after graduating as valedictorian from her high school, Jackson was accepted at M.I.T., where she was one of very few women and even fewer black students. Despite discouraging remarks from her professors about the appropriateness of science for a black woman, she chose to major in physics and earned her B.S. in 1968. Jackson continued at M.I.T. for graduate school, studying under the first black physics professor in her department, James Young. In 1973, she earned her Ph.D.

Shirley Jackson completed several years of postdoctoral research at various laboratories, such as Fermi in Illinois, before being hired by AT&T Bell Laboratories in 1976, where she worked for 15 years. She conducted research on the optical and electronic properties of layered materials, surface electrons of liquid helium films, strained-layer semiconductor superlattices, and most notably, the polaronic aspects of electrons in two-dimensional systems. She is considered a leading developer of Caller ID and Call Waiting on telephones.

After teaching at Rutgers University from 1991-1995, Jackson was appointed chair of the U.S. Nuclear Regulatory Commission by Bill Clinton. In 1999, Jackson became President of Rensselaer Polytechnic Institute, where she still serves today. In 2004, she was elected president of AAAS and in 2005 she served as chairman of the board for the Society. Dr. Shirley Jackson is married to a physicist and has one son.

[probablyasocialecologist]

The biggest tech companies in the world imagine a near future where AI will replace a lot of human labor, unleashing new efficiency and productivity. But this vision ignores the fact that much of what we think of as “AI” is actually powered by tedious, low-paid human labor.  “I think one of the mythologies around AI computing is that they actually work as intended. I think right now, what human labor is compensating for is essentially a lot of gaps in the way that the systems work,” Laura Forlano, Associate Professor of Design at the Institute of Design at Illinois Institute of Technology, told Motherboard. “On the one hand, the industry can claim that these things are happening, you know, magically behind the scenes, or that much of what's going on is the computing. However, we know that in so many different examples, whether we look at online content, how to operate an autonomous vehicle, or if we look at medical devices, human labor is being used to address the gaps in where that system really isn't able to work.” [...] Tech companies hire tens of thousands of gig workers to maintain the illusion that their machine-learning algorithms are fully self-functional, and that each new AI tool is capable of solving a number of issues out of the box. In reality, AI development has a lot more in common with material production cycles than we realize. “I think that the public doesn't have a good awareness of the fact that this is a supply chain. It’s a global supply chain, it contains uneven geographic flows and relations. And that it is based on a huge amount of human labor,” Kelle Howson, a postdoctoral researcher on the Fairwork project at the Oxford Internet Institute, told Motherboard.  Howson can’t say for sure whether tech companies are intentionally obscuring human AI laborers, but that doing so certainly works in their interests. “I think that in some ways it supports their business models to do so because there's this perception that the work is done,” said Howson. “You as a client access a platform interface, post your project, and the work is delivered immediately. It's almost like magic. There was maybe never any human involved or [that’s what] it feels like, and so there's a sense of efficiency. And that really goes along with the kind of narrative that Silicon Valley likes to tell. The disruption, the tech solutionism, the move fast and break things kind of ideas.”

[materialsscienceandengineering]

Nature-inspired patterns boost polymer toughness

Biological systems are renowned for their ability to create strong yet resilient structures. A sea sponge, for instance, grows in layers, forming unique patterns that integrate minerals with softer regions, creating an ideal balance of strength and flexibility. "Nature has a way of turning brittle materials into tough ones through intricate patterning," said Nancy Sottos, a researcher at the Beckman Institute for Advanced Science and Technology and head and Maybelle Leland Swanlund Endowed Chair in the Department of Materials Science and Engineering at the University of Illinois Urbana-Champaign. "Patterned materials often contain both stiff and soft regions, allowing them to withstand high strains without breaking while maintaining impressive strength." A study published today in Nature describes how Sottos and her colleagues used frontal polymerization, a process which uses heat to trigger a chemical reaction that forms polymers, to replicate nature's approach.

Read more.

[handeaux]

Dorelle Heisel Plumbed Brain Mysteries And Psychedelicized Cincinnati’s Social Circles

Dorelle Markley Heisel called Cincinnati her home for several decades, but her mind was in another dimension. She was known as “Cincinnati’s Brain Lady” and held college faculty positions in literature, psychology and fine art. She pioneered biofeedback techniques to control mental and bodily functions while introducing Cincinnati’s strait-laced society to the psychedelic subculture of the Sixties.

Virginia Dorelle Markley was born in 1917 in Danville, Illinois but spent her childhood shuttling between her father’s Palm Beach restaurant and her mother’s St. Louis hotel. At DePauw University in Greencastle, Indiana, she was student royalty – literally – voted May Queen in her senior year.

It was at DePauw that she met and became engaged to W. Donald Heisel, a Cincinnati native and Western Hills High School alumnus. At the time of his 1940 marriage to Dorelle, Heisel was assistant secretary to Cincinnati’s Civil Service Commission and was, according to the Cincinnati Enquirer [21 May 1940] “one of the city’s youngest executives.” The Heisels built a new house on a quiet cul de sac in Westwood, where they raised two daughters.

Don Heisel earned a reputation as the “godfather of public administration in the Tristate” [Cincinnati Enquirer 6 March 1988] because of the many governmental officials he mentored at the University of Cincinnati and at Xavier University. Dorelle, who had earned a degree in English from DePauw, added a bachelor’s (1952) and master’s (1965) in education from UC while also taking classes at the Cincinnati Art Academy.

Dorelle taught English for several years in Cincinnati high schools and at the Ohio Mechanics Institute. During the summers she was a fixture at Pogue’s Department Store. Hundreds of Queen City baby boomers likely display pastel portraits of themselves, sketched by Dorelle at her stand in the Pogue’s children’s department. She hated the drab institutional brown walls in her husband’s office, so one day she hauled her pastels over to City Hall and executed a large mural of the Cincinnati skyline, drawn from memory.

UC’s University College recruited Dorelle in the mid-1960s and she flourished there, teaching literature, art appreciation and psychology. With assistance from the Procter & Gamble company, she brought innovative technology into her classrooms with a push-button feedback device that allowed students to register immediate opinions regarding class content. She told the Cincinnati Post [14 March 1968]:

“When students become frustrated with a lecture or feel lost or just plain bored, they can indicate their anxiety by signaling me on the monitor.”

Dorelle’s interest in media and their effects on human communication led her to Canadian theorist Marshall McLuhan, known for his books “Understanding Media” and “The Medium Is The Massage.” Among the earliest mentions of McLuhan in Cincinnati newspapers is a reference to a 1966 Evening College class taught by Dorelle to introduce the Canadian theorist’s ideas to Cincinnati.

Simultaneously with her investigations of media and biofeedback, Dorelle dove into what was then known as the human potential movement. She presided over a multi-week UC Evening College class titled “Actualizing Your Potential: A Group Happening.” Enquirer reporter Jo Thomas sat in on the course and reported [21 August 1969] a most unusual classroom experience.

“I will not lecture,” Heisel said. “You will live out experiences, and I will ask you questions. Answer them in your head without verbalizing them. Writing is so slow and the mind works at such speed.”

Dorelle invited the students to form themselves into trains of about nine “cars,” kindergarten-style and take turns being the “engine” or the “caboose.”

“Elderly women hung on to 20-year-olds. Bald men chugged in front of bearded men. Around and around the room the trains went, gathering momentum and enthusiasm. One train burst out of the classroom door into the bright hall, chugging with gusto.”

The explosion of new ideas generated by the psychedelic Sixties energized Dorelle and she launched a series of public lectures to share her excitement. One wonders how her Cincinnati audiences, among such mainline organizations such as the Federation of Jewish Organizations and the Kiwanis Club, reacted to her exposition titled “Turn On, Tune In, Find Out!”

An early adopter of technology, Dorelle acquired a variety of devices to assist her research into altering thought patterns via biofeedback. Among these contraptions were the electromyograph and the alphaphone that made brainwaves audible or visual. She claimed that biofeedback, in addition to curing a variety of conditions from depression to migraines, transported users into a new state of being that she called the Kairos Dimension.

"The Kairos Dimension is nature taking its electronic course through you by providing strategies for amplifying your sensory range,” she announced in her 1974 book, “The Kairos Dimension.”

The titles of Dorelle’s non-credit classes and community lectures indicate the paths her biofeedback research led her down: “Brainfun: Steering Minds In New Directions,” “The Holographic Mind,” “How Biofeedback Opens Social Spaces,” and “How Biofeedback Supports Excitement And Growth.” Here is the course catalog description for one of these classes:

“Feelings of stress, tension and pressure take place only in muscles, never in the chemical-electrical brain that sends out orders. New research gives us a more accurate model of how we guide and control our range of ‘body sculptures.’ Small group exploration of the latest technologies.”

As the Human Potential movement evolved into various New Age philosophies, Dorelle’s biofeedback strategies caught on among that crowd. When the Montreal Star compiled a list of 50 important New Age books in 1975, Dorelle’s “Biofeedback Exercise Book” was featured along with books on transcendental meditation, herbal remedies, gestalt therapy and “The Joy of Sex.”

The nationally syndicated television show, P.M. Magazine, hosted Dorelle in November 1983 as “Cincinnati’s Brain Lady who enables you to see your brain on a television screen.” For a brief period, UC’s radio station WGUC aired a show devoted to Dorelle’s “Kairos Dimension.”

The Heisels divorced in 1977 and throughout the 1980s Dorelle’s public appearances waned. A Body/Mind/Spirit Festival at Avondale’s Unitarian Church in 1988 found her discussing biofeedback along with proponents of shamanism, tarot cards, crystals, chelation therapy and psychic powers.

Dorelle retired from UC and relocated to Plano, Texas where one of her daughters lived. In retirement, she played bridge and painted portraits. She died, aged 79, in November 1996.

[germanpostwarmodern]

Paul V. Galvin Library (1962) of Illinois Institute of Technology in Chicago, IL, USA, by Walter Netsch of Skidmore, Owings & Merrill

[lboogie1906]

Attorney King Virgil Cheek Jr. (May 26, 1937) is a lifelong educator, lawyer, and author.

He was born in Weldon, North Carolina to Lee Ella Williams Cheek and King V. Cheek Sr. The family moved to Greensboro, where he graduated from James B. Dudley High School.

He attended Bates College, majoring in economics, and received a BA. He went to the University of Chicago, receiving his MA and his JD from the University of Chicago Law School. He passed the Illinois State Bar and the North Carolina State Bar. He became active in the civil rights movement and participated in the March on Washington.

He served as professor, dean, and vice president before being appointed as president of Shaw at the age of thirty-two. He followed his older brother, James Edward Cheek, who had served as president of Shaw University. He became the eighth president of Morgan State University. He received an honorary Doctor of Laws degree from Delaware State College.

He married Annette Walker (1968) and the couple had four children. He is a member of Sigma Pi Phi Fraternity.

He became a professor of social sciences and dean of graduate studies at the New York Institute of Technology. He served as vice president and president of the Union for Experimenting Colleges and Universities, and he co-founded the Center for Leadership and Career Development in DC. He resumed his position as dean of graduate studies at the New York Institute of Technology. He was chancellor of the New York College of Health Professionals. He has written several articles, pamphlets, and books, including I See A New America: It Ain’t Like The One I Used To Know and The Quadrangle.

He served as the economic development consultant to the chief minister of Turks and Caicos Islands, director of the Senior Executive Development Program, Government of Bermuda, member of the board of directors of the Baltimore Museum of Art and the Baltimore Urban League, and member of the board of the North Carolina Association of Colleges and the Association of Eastern North Carolina Colleges. #africanhistory365 #africanexcellence #sigmaphiphi

[jcmarchi]

Unlocking mRNA’s cancer-fighting potential

New Post has been published on https://thedigitalinsider.com/unlocking-mrnas-cancer-fighting-potential/

Unlocking mRNA’s cancer-fighting potential

What if training your immune system to attack cancer cells was as easy as training it to fight Covid-19? Many people believe the technology behind some Covid-19 vaccines, messenger RNA, holds great promise for stimulating immune responses to cancer.

But using messenger RNA, or mRNA, to get the immune system to mount a prolonged and aggressive attack on cancer cells — while leaving healthy cells alone — has been a major challenge.

The MIT spinout Strand Therapeutics is attempting to solve that problem with an advanced class of mRNA molecules that are designed to sense what type of cells they encounter in the body and to express therapeutic proteins only once they have entered diseased cells.

“It’s about finding ways to deal with the signal-to-noise ratio, the signal being expression in the target tissue and the noise being expression in the nontarget tissue,” Strand CEO Jacob Becraft PhD ’19 explains. “Our technology amplifies the signal to express more proteins for longer while at the same time effectively eliminating the mRNA’s off-target expression.”

Strand is set to begin its first clinical trial in April, which is testing a proprietary, self-replicating mRNA molecule’s ability to express immune signals directly from a tumor, eliciting the immune system to attack and kill the tumor cells directly. It’s also being tested as a possible improvement for existing treatments to a number of solid tumors.

As they work to commercialize its early innovations, Strand’s team is continuing to add capabilities to what it calls its “programmable medicines,” improving mRNA molecules’ ability to sense their environment and generate potent, targeted responses where they’re needed most.

“Self-replicating mRNA was the first thing that we pioneered when we were at MIT and in the first couple years at Strand,” Becraft says. “Now we’ve also moved into approaches like circular mRNAs, which allow each molecule of mRNA to express more of a protein for longer, potentially for weeks at a time. And the bigger our cell-type specific datasets become, the better we are at differentiating cell types, which makes these molecules so targeted we can have a higher level of safety at higher doses and create stronger treatments.”

Making mRNA smarter

Becraft got his first taste of MIT as an undergraduate at the University of Illinois when he secured a summer internship in the lab of MIT Institute Professor Bob Langer.

“That’s where I learned how lab research could be translated into spinout companies,” Becraft recalls.

The experience left enough of an impression on Becraft that he returned to MIT the next fall to earn his PhD, where he worked in the Synthetic Biology Center under professor of bioengineering and electrical engineering and computer science Ron Weiss. During that time, he collaborated with postdoc Tasuku Kitada to create genetic “switches” that could control protein expression in cells.

Becraft and Kitada realized their research could be the foundation of a company around 2017 and started spending time in the Martin Trust Center for MIT Entrepreneurship. They also received support from MIT Sandbox and eventually worked with the Technology Licensing Office to establish Strand’s early intellectual property.

“We started by asking, where is the highest unmet need that also allows us to prove out the thesis of this technology? And where will this approach have therapeutic relevance that is a quantum leap forward from what anyone else is doing?” Becraft says. “The first place we looked was oncology.”

People have been working on cancer immunotherapy, which turns a patient’s immune system against cancer cells, for decades. Scientists in the field have developed drugs that produce some remarkable results in patients with aggressive, late-stage cancers. But most next-generation cancer immunotherapies are based on recombinant (lab-made) proteins that are difficult to deliver to specific targets in the body and don’t remain active for long enough to consistently create a durable response.

More recently, companies like Moderna, whose founders also include MIT alumni, have pioneered the use of mRNAs to create proteins in cells. But to date, those mRNA molecules have not been able to change behavior based on the type of cells they enter, and don’t last for very long in the body.

“If you’re trying to engage the immune system with a tumor cell, the mRNA needs to be expressing from the tumor cell itself, and it needs to be expressing over a long period of time,” Becraft says. “Those challenges are hard to overcome with the first generation of mRNA technologies.”

Strand has developed what it calls the world’s first mRNA programming language that allows the company to specify the tissues its mRNAs express proteins in.

“We built a database that says, ‘Here are all of the different cells that the mRNA could be delivered to, and here are all of their microRNA signatures,’ and then we use computational tools and machine learning to differentiate the cells,” Becraft explains. “For instance, I need to make sure that the messenger RNA turns off when it’s in the liver cell, and I need to make sure that it turns on when it’s in a tumor cell or a T-cell.”

Strand also uses techniques like mRNA self-replication to create more durable protein expression and immune responses.

“The first versions of mRNA therapeutics, like the Covid-19 vaccines, just recapitulate how our body’s natural mRNAs work,” Becraft explains. “Natural mRNAs last for a few days, maybe less, and they express a single protein. They have no context-dependent actions. That means wherever the mRNA is delivered, it’s only going to express a molecule for a short period of time. That’s perfect for a vaccine, but it’s much more limiting when you want to create a protein that’s actually engaging in a biological process, like activating an immune response against a tumor that could take many days or weeks.”

Technology with broad potential

Strand’s first clinical trial is targeting solid tumors like melanoma and triple-negative breast cancer. The company is also actively developing mRNA therapies that could be used to treat blood cancers.

“We’ll be expanding into new areas as we continue to de-risk the translation of the science and create new technologies,” Becraft says.

Strand plans to partner with large pharmaceutical companies as well as investors to continue developing drugs. Further down the line, the founders believe future versions of its mRNA therapies could be used to treat a broad range of diseases.

“Our thesis is: amplified expression in specific, programmed target cells for long periods of time,” Becraft says. “That approach can be utilized for [immunotherapies like] CAR T-cell therapy, both in oncology and autoimmune conditions. There are also many diseases that require cell-type specific delivery and expression of proteins in treatment, everything from kidney disease to types of liver disease. We can envision our technology being used for all of that.”