#iacc

[chavisory]

Hi all! The IACC is the committee that makes recommendations to the federal government regarding priorities in autism research. Currently they are seeking public comment (until February 14) on the subjects of autism and co-occurring physical and mental health conditions, and particularly the lasting impacts of societal changes associated with the Covid-19 pandemic, if those are issues important to you.

[otomobilist]

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[zsvpersticion]

[npzlawyersforimmigration]

Kusum Kaul Vyas, President of the IACC Gujarat Chapter, remarked on the success of the series, “The collaboration between IACC, Silver Oak University, NPZ Law Group, and CMB Swiss Co.-USA has been instrumental in enhancing economic ties and facilitating cross-border business ventures. We are thrilled with the turnout and the positive feedback received from participants.”

[marwahstudios]

Sandeep Marwah Designs New Projects for IACC Media and Entertainment Committee

New Delhi, January 26, 2024 – Dr. Sandeep Marwah, President of Marwah Studios and Chairman of the Media & Entertainment Committee, highlighted the potential for projecting the Indo American Chamber of Commerce (IACC) in a much larger perspective during the regional council meeting.

Emphasizing the need for continuous programs in the media and entertainment industry to elevate the Chamber’s stature, Dr. Marwah proposed significant initiatives. “I am delighted to offer three Radio Stations – Radio Noida 107.4FM, Radio Raipur, and Radio Mumbai – for any and every program of IACC,��� he announced. Additionally, he pledged to extend the coverage of IACC programs on MSTV of Marwah Studios.

The upcoming plans include participation in a seminar specially tailored for IACC during the 12th Global Festival of Journalism in Noida 2024, scheduled from February 12th to 14th. This will be followed by an international press conference for the Regional Council of IACC, culminating in a dynamic interaction program with the Asian Business School focusing on current India-USA relations.

During the meeting, Dr. Sandeep Marwah presented two of his books to Arun Karna, President of the Region Council and Managing Director/CEO at AT&T Global Network Services India Private Limited.

These initiatives reflect Dr. Marwah’s commitment to enhancing the presence and influence of IACC within the media and entertainment domain, fostering stronger ties between India and the United States.

[autisticadvocacy]

We have a great opportunity to share #ActuallyAutistic perspectives on autism research! The IACC is looking for public comments on research about conditions that commonly co-occur with autism. Learn more: https://autisticadvocacy.org/2024/01/share-your-thoughts-on-autism-research-with-the-iacc/

[covid-safer-hotties]

Also preserved on our archive

By Tarun Sai Lomte

New research reveals how lingering viral activity and immune disruption contribute to long COVID, highlighting novel therapeutic strategies that could change the course of treatment for millions.

A recent study published in the journal Cell reviewed the current state of knowledge on the pathophysiology and biology of long COVID.

Coronavirus disease 2019 (COVID-19) can affect health over the long term. Although it is self-limited in most individuals, some infected individuals experience post-acute sequelae, including fatigue, cognitive dysfunction, and muscle weakness, among others. While more common after severe COVID-19, individuals with a history of mild or moderate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have the highest burden.

The World Health Organization (WHO) defines post-COVID-19 condition as unexplained symptoms persisting ≥ two months that manifest ≥ three months after SARS-CoV-2 infection. Further, while many countries have adopted this definition, several have formulated their own definitions. The patient community that first identified the condition prefers the term long COVID.

Overall, the definitions vary in the time scale on which the condition is defined and whether the condition is restricted to unexplained patient-reported symptoms or inclusive of incident medical diagnoses/laboratory abnormalities. The present study reviewed the epidemiology of long COVID, with emphasis on how the underlying mechanisms explain the physiology. Additionally, the study highlights how symptom clusters, identified through techniques like cluster analysis in electronic health records (EHR), could improve long COVID diagnosis by linking specific biological drivers to clinical endotypes.

Epidemiology and clinical features of long COVID There are variations in epidemiological estimates of long COVID across variants, populations, and regions. Some studies suggest a prevalence of 30% or higher but define the syndrome as new unexplained symptoms, which might lead to misclassification. Not all symptoms may be related to SARS-CoV-2; as such, other conditions must be ruled out. Determining what is new after infection and what might be unmasking of sub- or pre-clinical conditions is a significant challenge.

Further, SARS-CoV-2 is not the only virus associated with protracted symptoms. Studies have estimated that 18 million adults in the United States (US) might suffer from long COVID. The WHO and the Institute for Health Metrics and Evaluation estimated that one in 30 European individuals had long COVID in the first three years of the COVID-19 pandemic. Globally, an estimated 65 million individuals have long COVID.

Notably, the epidemiology of severe, disabling long COVID-19 is unknown. Long COVID can manifest during or weeks after the acute infection. Cognitive problems, fatigue, and post-exertional symptoms are the most common. In addition, symptom clustering based on organ systems, such as autonomic dysfunction, neurocognitive impairment, and exercise intolerance, offers a more precise understanding of long COVID phenotypes. Further, many symptoms of long COVID overlap with those of other infection-associated chronic conditions (IACCs), such as chronic Lyme disease, post-Ebola disease, post-Giardiasis, and myalgic encephalitis/chronic fatigue syndrome, among others.

Biological drivers of long COVID The biological drivers of long COVID are upstream processes, such as perturbations of the coagulation system and immunity, which do not directly cause disease but instead drive one another, leading to downstream physiological changes that manifest as symptoms. Some of these biological processes, like clotting and immune dysfunction, may interact, creating a cycle of chronic inflammation and tissue damage. Microclots, resistant to fibrinolysis, have been detected in long COVID patients and may contribute to tissue hypoxia and organ dysfunction. There are also associations between viral activity levels during infection and long COVID risk, with higher viral replication linked to more severe illness.

Long COVID risk appears to be lower with Omicron variants. The protective effect of antiviral therapy and vaccination suggests that viral replication and transmission during the acute phase is a significant determinant of long-term outcomes. Therefore, early COVID-19 interventions could mitigate long COVID and support pursuing robust preventive agenda.

Early in the pandemic, it was commonly assumed that SARS-CoV-2 infection would be transient; however, this was challenged by reports that viral proteins and nucleic acids could be detected months after infection. Although the precise anatomic site of viral persistence is unclear, there is consensus that persistence is tissue-backed. Various studies have linked immune dysfunction and inflammation with long COVID.

Many studies have focused on the role of inflammatory macrophages and monocytes in long COVID. Mast cell activation might also contribute to long COVID. Although not infected by SARS-CoV-2, external triggers can activate mast cells. Severe COVID-19 is also associated with autoimmunity. COVID-19 is also associated with a higher incidence of autoimmune conditions, such as lupus, Sjogren’s syndrome, inflammatory bowel disease, and rheumatoid arthritis.

Acute SARS-CoV-2 infection can lead to a hypercoagulable state and elevate the risk of thromboembolic events. Interactions between the spike protein and fibrinogen may result in abnormal clots that can trigger microglia activation in the brain, potentially contributing to neurocognitive symptoms of long COVID. Clotting has been implicated as a long COVID mechanism, with aggregates of platelets and clotting proteins detected in affected individuals.

Clinical physiology of long COVID The most efficient explanation for long COVID is tissue damage mediated by SARS-CoV-2 that was initiated during (initial) infection. Pancreatic infection by SARS-CoV-2 has been implicated in post-COVID-19 diabetes, another form of the post-acute sequelae, offering proof of principle. Endothelial dysfunction has been suggested to be involved in long COVID.

Various mechanisms might lead to endothelitis and macrovascular diseases, and their end-organ consequences could result in long COVID. Additionally, the study suggests that microclots and endothelial dysfunction could impair tissue perfusion, leading to organ damage and contributing to persistent symptoms such as fatigue and cognitive issues. Disruption of the gut-brain axis enables a direct connection between post-COVID-19 processes and disruption of normal physiology, including brain fog, autonomic dysfunction, and abnormal stress responses.

Brain fog, i.e., problems with memory, concentration, and attention, is among the most debilitating manifestations of long COVID. It has been a prominent symptom among non-hospitalized patients since the early pandemic. Some people, especially those with diabetes, learning and attention disorders, and substance, have a predisposition for developing brain fog. Individuals with brain fog are more likely to have abnormal cerebrospinal fluid measures.

Concluding remarks The COVID-19 pandemic has been described as a once-in-a-century challenge, with long COVID representing a challenge of similar scale. Although long COVID is not the first known IACC, it is the first time that such a condition has manifested in a substantially large number of people following a shared, known exposure. Emerging therapies, including antivirals like nirmatrelvir/ritonavir and immunomodulators targeting inflammatory pathways, are currently being explored in clinical trials as potential treatments for long COVID. As such, there is an urgent need for all types of research (basic, epidemiological, translational, and clinical and implementation sciences) into the natural history, biology, and treatment for long COVID.

Journal reference: Peluso MJ, Deeks SG. Mechanisms of long COVID and the path toward therapeutics. Cell, 2024, DOI: 10.1016/j.cell.2024.07.054, www.sciencedirect.com/science/article/pii/S0092867424008869

[willowreader]

Feels like a good time for a thread about all things exercise for people living with infection (and exposure)-associated complex chronic illnesses (IACCs) such as #MECFS, #LongCOVID and chronic #Lyme /tick- and vector-borne illness. Let’s start with a trip down memory lane. 🧵 1/

A good conversation about the treatment of chronic illnesses and how patients have been ignored while desperately looking for treatment. This is an X thread. Click on the links.

[a-solitary-sea-rover-backup]

The Greatest Sailing Movie (N)Ever Made

Discussions of sailing movies online tend to circle around the same dozen names or so. How many errors did you spot in All is Lost? Was Master and Commander just too jargon-heavy to be a hit? Wind— love it or hate it? And just how bad is Waterworld?

But a recent discovery in the archives of Universal Studios revealed how close we almost came to having another name— or two?— in Hollywood’s somewhat dubious pantheon of the sport. While sorting old personnel files for digitization, archivist Tasha Durak discovered extensive material in the files of now-retired Universal screenwriter Avril Debile related to a project called Sunny Sets Sail. The documents suggest that Debile first got the idea for the story when visiting San Diego in 1991, during preparations for the following year’s America’s Cup competition.

Sunny Sets Sail (some documents use the title Sunny: America’s Pup) was to be a children’s sports comedy in a style common in the 1990s, combining cameos from real pro athletes with the hilarious antics of a fictional group of children— and, naturally, their adorable dog.

The story centered around Hannah, a young Navy brat recently moved to then-contemporary San Diego after spending most of her life overseas. Trying to help her feel more at home, Hannah’s parents give her a Newfoundland puppy named Sunny for her birthday and enroll her in lessons at a local sailing club. When Sunny tags along with Hannah to her first lesson, the instructor reluctantly allows the dog to accompany Hannah and her friends Jenny and Robby, noting the Newfoundland breed’s famous swimming abilities.

As the weeks pass by, Hannah, Jenny, and Robby discover Sunny is a natural crewmate, following commands to shift weight and pull on lines with her mouth. As there is nothing in the sailing club’s rules to prevent canine crew, the three compete in a junior racing series with Sunny onboard, and end up winning.

The prize is presented by Robby’s parents, Frank and June Arnold (apparently based on Peter and JJ Isler), who are both sailors for an American syndicate preparing to defend the America’s Cup. Sunny and the kids are invited to come watch the racing. They meet both the American team and the challengers, the usual sports movie band of villainous rivals, this time wearing an Australian coat of paint. (One draft which badly attempted to write out their dialogue phonetically was rejected by an editor for its potential to cause an international incident, as it sounded closer to a hideous mix of Cockney and Bostonian accents.)

The worst of them, of course, is challenging skipper Charlie “Crusher” Mackenzie, a bleach-blond meathead in sunglasses, introduced stepping on Sunny’s tail during a visit to the American compound and barking “Bloody mutt, I outta throw you overboard to the shahhks!” when she whines.

(Although few concrete references to the history of the America’s Cup are made during the script, Robby’s comment “The Australians. They won once before and they want it back.” seems to indicate a recent history vaguely like the real world’s.)

After Sunny jumps onboard the American IACC boat during a practice session and proves to be as adept at following commands as big boat crew as she did on the kids’ dinghy, Hannah and Robby suggest she become part of the American crew. At first, the skipper says no, but after losing the first two races of the match to the Australians, he relents.

Sunny, in a dog-sized windbreaker and ballcap with earholes, assists the Americans in the Cup match, and performs a traditional Newfoundland rescue when Mr. Arnold falls overboard during a maneuver. (In the first draft, she improbably swims fast enough to bring him back to the racing boat itself, in later drafts she more realistically drags him to a chase boat.)

As we might all hope, there indeed is a protest room scene where a white-haired old yachtsman adjusts his reading glasses, clears his throat, and declares “Nowhere in the America’s Cup Deed of Gift does it state that a dog cannot be part of a racing crew!”, followed, according to stage directions, by “swelling, triumphant music”.

Champagne being not-quite G-rated, the final victory scene features the spraying and guzzling of orange soda, and Sunny being showered with kibble poured out of the America’s Cup.

Avril Debile visited the 1992 and 1995 America’s Cups while researching the script, making connections with most American teams involved. The file contained a transcript of a research interview with the Islers and an educational brochure from the PACT 95 syndicate. Both Dawn Riley and Dennis Conner expressed interest in playing themselves in the film, although Conner wrote to Debile to request more lines.

While the commercial failure of Wind initially caused Universal to doubt the project, eventually Sunny Sets Sail was set for a tentative Summer 1996 release, a year after the America’s Cup, to help keep enthusiasm high for the next edition in San Diego. However, with Team New Zealand’s victory in the 1995 competition, the plot suddenly seemed dated, and production was shelved. A story with the heroes traveling to New Zealand as challengers was judged too complex for young audiences to understand. This was still the pre-Lord-of-the-Rings era in which American knowledge of New Zealand, among both children and adults, was judged to be nil. Avril Debile moved on to other projects, but the only one of note to sailing fans was the similar Tsunami: Extreme Cat. This film, created with input from Cam Lewis, would have covered a cat named Tsunami who stows away aboard a trimaran attempting the Jules Verne Trophy in her owner’s seabag. Although charming and with fewer scenes that strain belief, this script had the misfortune of being submitted to the studio in August 2001, just weeks before the 9/11 attacks changed national concerns. With the 90s extreme sports fad now out of fashion, Tsunami was also cancelled.

It’s easy at a distance of a quarter-century to look on these projects with regret, thinking of how they might have raised the public profile of sailing in the USA. As cheesy and corny as the plots sound— surely if they had been made, “Sunny the dog” and “The Deed of Gift does not forbid dogs!” would be as much of a running joke on Scuttlebutt as “The Whomper”— they could have made the sport of sailing part of the childhood of an entire generation of young people.

Our cold comfort is that it is widely suspected that the scripts for Sunny Sets Sail that were passed around Hollywood in the early-mid 90s could have inspired other films of the era about improbable animal athletes, such as Air Bud, Racing Stripes, and MVP: Most Valuable Primate.

“Avril” is of course French for “April”, and “Débile” means “Stupid” or “Foolish”.

[liminalweirdo]

Think you might have Long Covid?

Symptoms:

General Symptoms:

Tiredness or fatigue

Symptoms that get worse after physical or mental effort

Fever

Neurological Symptoms:

Difficulty thinking or concentrating

Headache

Sleep problems

Lightheadedness

Pins-and-needles feelings

Change in smell or taste

Depression or anxiety

Digestive Symptoms:

Diarrhea

Stomach pain

Respiratory and Heart Symptoms:

Difficulty breathing or shortness of breath

Cough

Chest pain

Fast-beating or pounding heart.

Other Symptoms:

Joint or muscle pain

Rash

Changes in menstrual cycles

And more...

Routine blood tests, chest x-rays, and electrocardiograms may be normal in patients with Long COVID. The CDC describes the symptoms as similar to those reported by people with ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) and other multi-system chronic complex diseases (msCCD).

These unexplained symptoms may be misunderstood by healthcare providers, which causes a delay in diagnosis and appropriate treatment. Patients with Long COVID may also present with single or multiple symptoms of varying severity.

There is no specific test to diagnose Long COVID, so doctors usually consider a diagnosis of Long COVID based on health history, current symptoms, and a health examination.

The National Academies of Sciences, Engineering, and Medicine have developed a case definition for Long COVID to facilitate diagnosis. They have defined Long COVID as an infection-associated chronic condition (IACC) that occurs after SARS-CoV-2 infection and is present for at least 3 months as a continuous, relapsing and remitting, or progressive disease state that affects one or more organ systems.

source

to learn more, or to support research into chronic illnesses like Long Covid, ME/CFS, Chronic Lyme Disease, and more, check out

Open Medicine Foundation (USA)

Open Medicine Foundation (Canada)

Open Medicine Foundation (Australia)

[kahecha82]

Han pensado esto ???????........ Por qué estoy en el celular ??????............. El lunes tengo prueba.......... Lo único bueno está vez es on line............ Trabajo social en iacc..........

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[ferrarireplicawatchx876r]

How to Report a Cartier Fake: A Comprehensive Guide

When investing in luxury items like Cartier watches, ensuring authenticity is crucial. Unfortunately, counterfeit products flood the market, tricking unsuspecting buyers. If you've fallen victim to a fake Cartier watch or suspect someone else has, knowing how to report it is essential. This guide will walk you through the steps of reporting a Cartier fake, while also highlighting the importance of shopping from reputable sources, like Luxe Replica Watche.

Understanding the Problem of Counterfeit Cartier Watches

Counterfeit Cartier watches not only deceive buyers but also damage the brand's reputation and sales. These replicas can be deceptively similar to authentic pieces, making it difficult for consumers to distinguish between the two. By reporting fakes, you help protect the integrity of luxury brands and aid others in avoiding similar pitfalls.

Steps to Identify a Fake Cartier Watch

Before reporting a fake Cartier watch, you should first determine its authenticity. Here are some indicators that can help you identify a counterfeit:

Check the Serial Number: Authentic Cartier watches have unique serial numbers. Verify this number through Cartier’s official website or customer service.

Examine the Craftsmanship: Real Cartier pieces exhibit exceptional craftsmanship. Look for uneven edges, poor engraving, or low-quality materials.

Inspect the Weight: Genuine Cartier watches are often heavier due to high-quality materials. A noticeably light watch may indicate a fake.

Review the Packaging: Authentic Cartier watches come in high-quality packaging with certificates of authenticity. If the packaging looks cheap, it’s likely a counterfeit.

How to Report a Fake Cartier Watch

If you’ve confirmed that you have a counterfeit Cartier watch, follow these steps to report it:

1. Gather Evidence

Collect all pertinent information about the fake watch. This includes:

Photos of the watch

Details about where and when you purchased it

Any communication with the seller

2. Contact Cartier

Reach out to Cartier’s customer service or their official website. Provide them with all the evidence you have collected. They may ask for additional information to assist with their investigation.

3. Report to Consumer Protection Agencies

In many countries, you can report counterfeit products to consumer protection agencies. In the United States, for example, you can contact the Federal Trade Commission (FTC) or your local state attorney general's office. Provide them with all the evidence you've gathered.

4. Use Online Reporting Tools

Websites like the International AntiCounterfeiting Coalition (IACC) allow you to report counterfeit products online. Fill in the required information, attach your evidence, and submit your report.

5. Notify Online Marketplaces

If you purchased the watch through an online platform (like eBay or Amazon), report the seller. These platforms have policies against counterfeit goods and may take action against the seller.

Educate Others

One of the most effective ways to combat counterfeit products is through education. Share your experience with friends, family, and social media followers. Inform them about the risks of purchasing luxury items from unverified sources.

Shop Wisely: Why Luxe Replica Watche is a Safe Choice

When looking for high-quality replica watches, it's essential to choose a reputable source. Luxe Replica Watche is committed to providing premium replica watches that mimic the style of luxury brands without compromising quality. Our commitment to transparency and customer satisfaction makes us a reliable choice for your shopping needs.

Conclusion

Reporting a counterfeit Cartier watch is not only about protecting yourself but also about safeguarding the integrity of luxury brands. By following the steps outlined in this guide, you can make a difference. Always remember to shop wisely and consider trustworthy retailers like Luxe Replica Watche for replica watches that meet high standards of quality.

[marwahstudios]

Sandeep Marwah Reappointed as Chair for M&E Committee in IACC

New Delhi: Distinguished film, TV, and media personality, Dr. Sandeep Marwah, has once again been nominated as the Chair for the Media and Entertainment Committee of the Indo American Chamber of Commerce (IACC) in New Delhi.

Dr. Marwah, a prominent figure in the global entertainment industry, expressed his gratitude for the reappointment, stating, “It is an honor to continue my association with the Indo American Chamber of Commerce and contribute to the dynamic field of media and entertainment in the Indo-American business landscape. My personal connection with the United States further strengthens my commitment to fostering collaboration between the two nations.”

The announcement was met with congratulations from key figures within the IACC. Arun Karna, Regional President North and Managing Director of AT&T Global Network Services P Ltd, along with Upasana Arora, former President IACC North Chapter and Managing Director of Yashoda Super Speciality Hospitals, extended their warm congratulations to Dr. Marwah.

Dr. Marwah, also the President of the International Chamber of Media and Entertainment Industry (ICMEI), highlighted the significance of fostering strong ties with the United States, noting, “At ICMEI, we have a dedicated committee focusing on the United States, emphasizing the importance of cultural and economic collaboration between the two nations.”

The Media and Entertainment Committee of IACC, under Dr. Marwah’s leadership, is expected to play a pivotal role in enhancing cooperation and exploring opportunities in the dynamic and rapidly evolving media and entertainment sector.

As a respected industry veteran and cultural ambassador, Dr. Sandeep Marwah’s continued involvement in the IACC is expected to further strengthen the ties between India and the United States, especially in the field of media and entertainment.

[jordanianroyals]

25 August 2024: King Abdullah II received the Integrity and Anti-Corruption Commission’s (IACC) report for 2023. His Majesty stressed the need to maintain efforts to further develop the commission and build the capacities of its staff.

He also met with Chief Islamic Justice Abdul Hafez Rabtah and Higher Sharia Court President Kamal Smadi to receive a copy of the annual Sharia Courts report for 2023, His Majesty stressed the need to continue building the capacities of judges and supporting staff. According to Rabtah, more than 9,000 families were reconciled through the courts’ family reconciliation offices, while more than 40,000 cases reached amicable settlements.

[autisticadvocacy]

The IACC recommends where federal research funds for autism research should go. The IACC is looking for public comments on research about conditions that commonly co-occur with autism. Learn more: https://autisticadvocacy.org/2024/01/share-your-thoughts-on-autism-research-with-the-iacc/

[theshillongtimes]

US must speed up process for issuing tourist visa, says top Indian official

New Delhi, Aug 23: There is a need to expedite the “cumbersome” process of getting a US visa that Indian nationals face, to promote tourism between the two countries which enjoy a strong bilateral partnership, a top Tourism Ministry official said on Friday.

Suman Billa, Additional Secretary, Union Ministry of Tourism said, that although a US visa is valid for 10 years and does not require any frequent updates by a visa holder, the process of getting a visa for the world’s largest economy is a cumbersome and tiresome process and to boost Indo-US tourism, swifter visa approval and more direct flights between India and the US is needed.

Speaking at the Indo-US Tourism & Hospitality Summit, organised by the Indo-American Chamber of Commerce (IACC) here, Billa said: “I think the best thing about getting a US visa is that once you have it, it’s valid for 10 years. So there’s not a lot of repeat visitation that happens. But you have to really walk through fire to get that visa in the first place because there are long waiting times now and, you know, so there’s a whole lot of disincentive for people wanting to travel.”