#glucophage

[edwinscotte9947]

Metformin HCl (Generic Glucophage)

Metformin HCl, commonly sold under the generic name Glucophage, is one of the most widely prescribed oral medications used to manage Type 2 Diabetes. It belongs to a class of drugs known as biguanides and is particularly effective for people who have difficulty controlling their blood sugar through diet and exercise alone.

Metformin works by:

Decreasing glucose production in the liver.

Improving the body’s sensitivity to insulin, which allows sugar (glucose) to be better absorbed by cells.

Reducing the absorption of glucose from food in the intestines.

By improving how the body uses insulin, Metformin helps to lower blood sugar levels, reducing the risk of serious complications associated with diabetes, such as heart disease, nerve damage, and kidney problems.

For those looking to manage their diabetes effectively and affordably, DiRx offers Metformin HCl (Generic Glucophage) at a fraction of the cost. No insurance is needed DiRx provides FDA-approved generic medications directly to consumers.

How Does Metformin HCl Work?

Metformin helps manage blood sugar levels through a multi-faceted approach:

Inhibiting glucose production by the liver: This reduces the amount of sugar entering the bloodstream.

Improving insulin sensitivity: The drug makes the body more responsive to insulin, helping cells absorb glucose more efficiently.

Decreasing intestinal absorption of glucose: This ensures that less sugar is absorbed from food.

These combined actions help keep blood sugar levels stable throughout the day and are especially helpful for those with Type 2 Diabetes. Metformin can be used alone or in combination with other diabetes medications or insulin to achieve optimal blood sugar control.

If you're looking for a cost-effective way to get your diabetes medications, consider ordering Metformin HCl (Generic Glucophage) through DiRx. Visit DiRx to save on your prescription today.

Why Choose DiRx for Metformin HCl?

DiRx offers high-quality, FDA-approved generic medications at a fraction of the cost, delivered directly to your door. With DiRx, you can:

Save Money: Medications like Metformin HCl are available at significantly lower prices compared to traditional pharmacies.

Skip Insurance Hassles: There’s no need for insurance or copays—DiRx provides transparent pricing for everyone.

Enjoy Convenience: Order online and have your medication delivered to your home, saving you time and hassle.

Explore DiRx today and find out how easy and affordable it is to manage your diabetes with Metformin HCl.

[mithliya]

"there's research coming out to suggest polycystic ovary syndrome doesn't even require ovaries" - very smart person.

anyways i said "as if hyperandrogenism isnt a hallmark of PCOS". hallmark literally means "a distinctive feature" ie defining feature. you're over here calling me stupid and then backtracking and repeating exactly what you called me stupid for.

there's obviously a major difference between a brown woman and a racist or a misogynist lmao. u wanting to appropriate intersex struggles & throwing terms like terf at me doesn't change anything.

is PCOS intersex? (assuming hyperandrogenism & female pcos, not other kinds)

[radgritty]

Anyone on Metformin (Glucophage) or Rosuvastatin (Crestor)? Do they work?

[living-glacier]

Niby biorę Glucophage (na PCOS) a i tak nie chudnę! Waga stoi w miejscu, wczoraj dostałam okres, więc w sobotę mogę się zważyć, boję się, że będzie chociaż o 0,1 kg więcej.

Mój "facet" powiedział mi, że może i jestem "większa", ale jemu podoba się mój charakter...

Lepiej jest być "fajną" w fajnym ciele, szczupłym, skinny...

Nienawidzę go, jak mógł to powiedzieć?!?!

[dyingroses]

Writing some reflections by the light of the trashcan fire that is our world:

So I was talking with my therapist about how scary the world is and how angry I am as I feel helpless to stop the powers trying to turn my country into Gilead

The world is a trashcan fire

It’s always been a trashcan fire

Later in the session the Rodney King assault and the OJ Simpson trial came up and my therapist was saying how it was such a scary time, watching as no one was held accountable 

‘Such a scary time’

I took strange comfort in that statement

Because it shows life goes on

I feel guilty for saying so because I’m not one of the oppressed

I live in a sanctuary state

For many life ends

But love and joy will still live on

We briefly talked about Derry Girls

How it showed how the best and worst moments of your life can coincide

How we’re all living through something

We’re dancing at the talent show while people in our town search wreckage for survivors of a bombing

We’re dancing

Dance will live on

Persian father dancing at his daughters grave, having promised to dance at her wedding

And

My patient eagerly following me in the Y.M.C.A this morning

My patient in a mental hospital

‘It must be so sad’ and ‘It must be so hard to work in a mental hospital’

Sometimes it is, most of the time it’s not

Sometimes it give me this bit of beauty

This bit of comfort, of hope

I forgot to do it today, but most times I give him his medication I remind him how far he’s come in managing his diabetes

From insulin injections multiple times a day to just glucophage 

My coworker walked in with a smile on her face and a bounce in her step, easier day and holiday pay, and the the Lizzo x AristoCats video I showed her

SCOTUS terrifies as they rule more discrimination and oppression legal

They rule businesses can discriminate against queer people

And we keep on breathing through memes about not serving straights

We keep on breathing 

We’re still here - a lyric in a song I heard about an earthquake - a video I saw at the end of a terrible time living with my biological father - a time I got through

We keep on breathing

We have always been here

“That’s just the way of the world, it never ends till it ends then you start again” (depressing)

“That’s just the way of the world, it never ends till it ends then you start again” 

(Queers living on and fighting)

[mwsrwritings]

Metformin, When To Take It

Timing is everything for many things in life — including when to take medication like metformin, sold under the brand names Glucophage, Fortamet, Riomet, and Glumetza. So, when’s the best time to take metformin? Well, there’s no magic time, but you should take metformin at the same time each day and with food to avoid gastrointestinal side effects. If you’re taking extended-release metformin…

[novaglobalhealthcare]

What Are My Options for Type 2 Diabetes Medications?

There are different types, or classes, of medications that work in different ways to lower blood glucose (also known as blood sugar) levels. Some options are taken by mouth and others are injected. Some of the commonly used classes of non-insulin medications include:

Metformin

Dipeptidyl peptidase 4 (DPP-4) inhibitors

Glucagon-like peptide 1 (GLP-1) and dual GLP-1/gastric inhibitory peptide (GIP) receptor agonists

Sodium-glucose cotransporter 2 (SGLT2) inhibitors

Sulfonylureas

Thiazolidinediones (TZDs)

Metformin

Metformin (Glucophage) is classified as a biguanide medication and is the only available medication in this class. Metformin lowers blood glucose levels primarily by decreasing the amount of glucose produced by the liver. Metformin also helps lower blood glucose levels by making muscle tissue more sensitive to insulin so blood glucose can be used for energy.

It is usually taken two times a day. A side effect of metformin may be diarrhea, but this is improved when the drug is taken with food.

DPP-4 Inhibitors

DPP-4 inhibitors help improve A1C (a measure of average blood glucose levels over two to three months) without causing hypoglycemia (low blood glucose). They work by preventing the breakdown of naturally occurring hormones in the body, GLP-1 and GIP. These hormones reduce blood glucose levels in the body, but they are broken down very quickly so it does not work well when injected as a drug itself.

By interfering in the process that breaks down GLP-1 and GIP, DPP-4 inhibitors allow these hormones to remain active in the body longer, lowering blood glucose levels only when they are elevated. DPP-4 inhibitors do not cause weight gain and are usually very well tolerated.

There are four DPP-4 inhibitors currently on the market in the U.S.:

Alogliptin (Nesina)

Linagliptin (Tradjenta)

Saxagliptin (Onglyza)

Sitagliptin (Januvia)

GLP-1 and Dual GLP-1/GIP Receptor Agonists

As noted in the description for DPP-4 inhibitors, GLP-1 and GIP are natural hormones in the body that help maintain glucose levels. Use of GLP-1 and dual GLP-1/GIP receptor agonists is another strategy to help use these hormones to improve blood glucose management in people with type 2 diabetes.

These medications have similar effects to the GLP-1 and GIP produced in the body but are resistant to being broken down by the DPP-4 enzyme. These medications can result in large benefits on lowering blood glucose and body weight. Some agents in this class have also been shown to prevent heart disease. Most of these medications are injected, with the exception of one that is taken by mouth once daily, called semaglutide (Rybelsus).

Injectable GLP-1 receptor agonists currently on the market include:

Dulaglutide (Trulicity)

Exenatide (Byetta)

Exenatide extended-release (Bydureon)

Liraglutide (Victoza)

Lixisenatide (Adlyxin)

Injectable semaglutide (Ozempic)

One dual GLP-1/GIP receptor agonist is currently on the market called tirzepatide (Mounjaro). How often you need to inject these medications varies from twice daily to once weekly, depending on the medication. The most common side effect with these medications is nausea and vomiting, which is more common when starting or increasing the dose.

SGLT2 Inhibitors

Glucose in the bloodstream passes through the kidneys where it can either be excreted in the urine or reabsorbed back into the blood. Sodium-glucose cotransporter 2 (SGLT2) works in the kidney to reabsorb glucose. A new class of medication, SGLT2 inhibitors, block this action, causing excess glucose to be eliminated in the urine.

By increasing the amount of glucose excreted in the urine, people can see improved blood glucose, some weight loss, and small decreases in blood pressure. Bexagliflozin (Brenzavvy), canagliflozin (Invokana), dapagliflozin (Farxiga), and empagliflozin (Jardiance) are SGLT2 inhibitors that have been approved by the Food and Drug Administration (FDA) to treat type 2 diabetes. SGLT2 inhibitors are also known to help improve outcomes in people with heart disease, kidney disease, and heart failure.

For this reason, these medications are often used in people with type 2 diabetes who also have heart or kidney problems. Because they increase glucose levels in the urine, the most common side effects include genital yeast infections.

Sulfonylureas

Sulfonylureas have been in use since the 1950s and they stimulate beta cells in the pancreas to release more insulin. There are three main sulfonylurea drugs used today, glimepiride (Amaryl), glipizide (Glucotrol and Glucotrol XL), and glyburide (Micronase, Glynase, and Diabeta). These drugs are generally taken one to two times a day before meals.

All sulfonylurea drugs have similar effects on blood glucose levels, but they differ in side effects, how often they are taken, and interactions with other drugs. The most common side effects with sulfonylureas are low blood glucose and weight gain.

TZDs

Rosiglitazone (Avandia) and pioglitazone (Actos) are in a group of drugs called thiazolidinediones. These drugs help insulin work better in the muscle and fat and reduce glucose production in the liver.

A benefit of TZDs is that they lower blood glucose without having a high risk for causing low blood glucose. Both drugs in this class can increase the risk for heart failure in some individuals and can also cause fluid retention (edema) in the legs and feet.

[edwinscotte9947]

Metformin HCl Extended Release (Generic Glucophage XR)

Metformin HCl Extended Release (ER), commonly known as Generic Glucophage XR, is an oral medication used to manage Type 2 Diabetes. It belongs to the biguanide class of drugs and is designed to help control high blood sugar in adults. The extended-release formulation is beneficial for individuals who prefer once-daily dosing, as it releases the drug slowly into the bloodstream over time.

Metformin ER works by:

Decreasing glucose production in the liver.

Improving insulin sensitivity, allowing glucose to be more effectively used by the body’s cells.

Reducing glucose absorption from food.

For patients looking for affordable options to manage their diabetes, DiRx offers Metformin HCl Extended Release (Generic Glucophage XR) at competitive prices, delivered right to your doorstep without requiring insurance. Visit DiRx to learn more about how you can save on your prescriptions.

How Does Metformin HCl Extended Release (Glucophage XR) Work?

Metformin HCl ER is designed to release its active ingredient gradually throughout the day, ensuring more consistent blood sugar control over 24 hours. The mechanism of action includes:

Inhibiting the liver’s glucose production: This limits the amount of glucose that enters the bloodstream.

Improving the body's response to insulin: This allows cells to absorb glucose more efficiently.

Reducing glucose absorption in the intestines: It ensures that less sugar from food is absorbed into the bloodstream.

This extended-release version is especially beneficial for those seeking a more convenient dosing schedule, as it can typically be taken once a day. You can purchase Metformin HCl ER (Glucophage XR) easily and affordably through DiRx, where you don’t need insurance to access FDA-approved medications. Visit DiRx today to explore your options.

Why Choose DiRx for Metformin HCl ER?

DiRx provides affordable access to FDA-approved generic medications like Metformin HCl ER, allowing patients to save significantly on their prescription costs. Here’s why you should choose DiRx:

[phonemantra-blog]

Benefits of Metformin - Outranking the Competition When it comes to managing diabetes, Metformin has emerged as a popular and effective medication. In this article, we will explore the numerous benefits of Metformin and how it can positively impact your health. By providing comprehensive information, we aim to help you understand why Metformin is a valuable option for diabetes management. The Role of Metformin in Diabetes Management Metformin, also known by its brand names Glucophage, Glumetza, and Fortamet, is an oral medication that belongs to the biguanide class. It is primarily prescribed to individuals with type 2 diabetes, but it may also be used in combination with other medications for type 1 diabetes. Metformin works by reducing the amount of glucose produced by the liver and improving the body's response to insulin. This helps to lower blood sugar levels and maintain them within a healthy range. It also aids in weight loss and reduces the risk of cardiovascular complications associated with diabetes. Benefits of Metformin Blood Sugar Control One of the key benefits of Metformin is its ability to effectively control blood sugar levels. By reducing the production of glucose in the liver and enhancing insulin sensitivity, it helps to regulate blood sugar levels and prevent spikes and crashes. This is crucial for individuals with diabetes to maintain stable blood sugar levels throughout the day. Weight Loss Metformin can also aid in weight loss, which is beneficial for individuals with type 2 diabetes who often struggle with obesity. It helps to reduce appetite and inhibit the absorption of glucose from the digestive system, leading to gradual and sustainable weight loss over time. Cardiovascular Protection Studies have shown that Metformin can provide cardiovascular protection to individuals with diabetes. It helps to reduce the risk of heart disease, heart attacks, and strokes by improving lipid profiles, reducing inflammation, and preventing the formation of blood clots. This makes it an invaluable medication for those looking to safeguard their cardiovascular health. Improved Fertility Metformin is beneficial for individuals with polycystic ovary syndrome (PCOS), a condition that often leads to infertility. By regulating hormone levels and restoring ovulation, Metformin can help improve fertility and increase the chances of successful pregnancy in women with PCOS. Lower Cancer Risk Emerging research suggests that Metformin may have a protective effect against certain types of cancer. Studies have shown that it can inhibit the growth of cancer cells and reduce the risk of developing colorectal, breast, and prostate cancers. While more research is needed, this potential benefit adds to the overall value of Metformin for individuals with diabetes. [caption id="attachment_73160" align="aligncenter" width="675"] benefits of metformin[/caption] Metformin is a powerful medication that offers numerous benefits for individuals with diabetes. From blood sugar control to weight loss, cardiovascular protection, improved fertility, and potentially lower cancer risk, it plays a vital role in managing the condition effectively. By understanding the benefits of Metformin, you can make informed decisions about your diabetes management plan in consultation with your healthcare provider. Remember, always follow your doctor's instructions and never make changes to your medication regimen without professional guidance. Frequently Asked Questions about the Benefits of Metformin 1. What is metformin? Metformin is an oral medication commonly prescribed to manage type 2 diabetes. It helps control blood sugar levels by improving insulin sensitivity and reducing glucose production in the liver. 2. How does metformin benefit people with diabetes? Metformin offers several benefits for individuals with diabetes, including lowering blood sugar levels, reducing the risk of cardiovascular complications, aiding weight loss, and improving overall insulin sensitivity. 3. Can metformin help with weight loss? Yes, metformin can assist in weight loss for individuals with diabetes. It may help reduce appetite, lower calorie intake, and improve the body's ability to use insulin effectively, leading to weight loss over time. 4. Does metformin have any cardiovascular benefits? Yes, metformin has been shown to have cardiovascular benefits. It can help lower the risk of heart attacks, strokes, and other cardiovascular complications in individuals with diabetes. 5. Are there any other health benefits associated with metformin? Aside from its benefits in managing diabetes, metformin has been studied for its potential to reduce the risk of certain cancers, improve fertility in women with polycystic ovary syndrome (PCOS), and slow down the aging process. 6. Can metformin be used by non-diabetic individuals? Metformin is primarily prescribed for individuals with diabetes. However, in some cases, it may be prescribed off-label to treat conditions such as polycystic ovary syndrome (PCOS) or to aid in weight loss for non-diabetic individuals with insulin resistance. 7. Are there any side effects of metformin? Like any medication, metformin can have side effects. Common side effects include gastrointestinal issues like nausea, diarrhea, and stomach upset. However, these side effects are usually temporary and diminish over time. 8. Can metformin be taken during pregnancy? It is important to consult with a healthcare professional if you are pregnant or planning to become pregnant before taking metformin. In some cases, it may be prescribed for women with gestational diabetes, but individual circumstances will determine its suitability. 9. Can metformin be taken with other medications? Metformin can be taken with certain other medications, but it is crucial to inform your healthcare provider about all the medications you are taking to avoid potential interactions. They can guide you on the safe and effective use of metformin in combination with other drugs. 10. How long does it take for metformin to show its benefits? The effectiveness of metformin varies from person to person. Some individuals may experience improvements in blood sugar control within a few days, while for others, it may take a few weeks. Consistent use and regular monitoring are essential to assess its benefits.

[moonheart201996]

👈 افضل علاج لمقاومه الانسولين والتخلص منها نهائيا

والقضاء على اثارها الجانبيه

علاج مقاومه انسولين

Glucophage

مره بعد الغداء بساعه

Chromitron

مرتين يوميا قبل الاكل بنص ساعة

شرب ٢كوب قرفه

شرب ٢كوب قهوه خضراء

تقليل السكر او منعه

تقليل نسب النشويات

عدم السهر ليلا

[pranaliahuja12]

What are the key distinctions between metformin and Glipizide? 

Metformin and Glipizide are the two medicines used for treating type 2 diabetes. People with this type of diabetes have an issue with the hormone insulin, which is responsible for shifting the glucose in the body's cells for acquiring energy. When insulin does not work appropriately, insulin resistance will develop and lead the increased levels of sugar in the body, which can cause other health issues. Hence metformin and Glipizide are used to manage the higher glucose levels to reduce the chances of complications from diabetes. Many glipizide manufacturers are known in the industry for developing the best Glipizide. To learn more about Glipizide, it is necessary to understand the difference between the two. Read this article to learn more. 

What Medical Conditions Do Metformin and Glipizide Treats? 

The FDA approves Metformin and Glipizide for the treatment of type 2 diabetes. Controlling the higher blood glucose levels will reduce the chances of other health conditions caused by diabetes. These complications are kidney, heart, and liver diseases, eye damage, and foot infections. 

Metformin has an off-label use for treating other conditions such as diabetes during pregnancy or for gestational diabetes, PCOS. It is also used for treating weight gain caused by certain antipsychotic medications’ side effects. 

What is The Difference Between Glipizide and Metformin? 

Glipizide 

It is the generic name of Glucotorol and is from the medication group known as Sulfonylureas. Glipizide manufacturers say that it works by stimulating insulin secretion from the pancreas. This increase in insulin will lower the blood glucose levels in the body. Many people can buy Glipizide in 5-10mg, an oral tablet. You can also buy the generic version, which is available in controlled-release tablets in 2.5-10mg pills. Doctors suggest patients use Glipizide once a day in the morning on an empty stomach. 

Metformin 

Metformin is the generic form of Riomet and Glucophage and is from the medicine family called Biguanides. This medication is used for treating type 2 diabetes by reducing the production of glucose in the liver and reducing glucose absorption in the intestines. It also increases insulin sensitivity and glucose uptake in the body’s tissues.  

Metformin is accessible in tablet forms in the strengths of 500mg, 850mg, and 1000mg. The immediate-release form is used twice a day. Doctors also suggest extended-release medication, which should be taken once a day. 

Is Glipizide Effective Than Metformin? 

Glipizide manufacturers say that both substances are effective for diabetes and enhance glycemic control in people with type 2 diabetes. They are also used as the combination pill called Metaglip. These medications work best if used with exercise and a clean diet. 

According to the guidelines left by the ADA, metformin will remain the first-line treatment for type 2 diabetes. In terms of effectiveness in those with type coronary artery disease and type 2 diabetes, metformin will reduce the chances of heart attack and stroke.  

To ensure the Glipizide is authentic, look for the 29094 61 9 number. These are the difference between the top type 2 diabetes medications. Before making any purchases, it is necessary to consult with a doctor since they will suggest the best medication. 

This article talks about the difference between Metformin and Glipizide. Supra Chemicals is a leading manufacturing and exporting company for medicines like Glipizide and Indapamide.  

[phantomtutor]

SOLUTION AT Academic Writers Bay According to Nicole Paolini Albanese, lead author of the Journal of the American Pharmacists Association, “Weight loss is a good quality for diabetic medications, as being overweight is a frequent feature of the illness, and can ultimately lead to reduced insulin sensitivity. She also states, “With weight loss, it is possible to regain insulin sensitivity, improve glucose control and reduce heart risk factors and comorbidities (Robinson 2021).” A UB-led study discovered that patients with Type 2 diabetes who were given SGLT2 inhibitors dropped more weight than those who obtained GLP-1 receptor agonists. The GLP-1 mimics the activity of a hormone known as glucagon-like peptide when blood sugar levels rise after someone eats, these drugs promote the body to produce extra insulin. The additional insulin improves lower blood sugar levels (Castro 2021). On the other hand, SGLT2 inhibitors work uniquely and separately to reduce your blood sugar. They curtail the activity of proteins, so-called sodiumglucose cotransporter 2, that improves the kidney’s reabsorb glucose (sugar) from the blood. After taking SGLT2 inhibitors, a smaller amount of blood sugar ends up in the kidneys, and extra of it leaves the body in your urine (Rope & Dansinger 2020). A. Which classes of diabetes medications are eighter weight neutral or cause weight loss? Please give one (1) example of a drug’s generic and trade name in the class. The kidneys have a structure to attract and recognize glucose from the urine known as the sodium-glucose-luminal-cotransporters 1 and 2, and SGLT21’s impede and prevent that absorption. SGLT2 inhibitors are just the once-regular tablets that affect nor trigger the kidneys to distribute glucose into the urine, usually 65 to 100 grams daily roughly 400 calories. The dropping of 400 calories each day would decrease a person to dust in no time. Still, the body has numerous compensatory procedures, so the weight ultimately plateaus, and a few people, in some way, don’t drop considerable weight even though others lose 10-15 lbs (Einhorn 2019). Trade Name : Ertugliflozin Generic Name : Stegliatro FDA Approval: 2017 Dose: 5-15 Daily B. Based on the current guidelines of the ADA, it would be appropriate to treat her with monotherapy since the patient is hesitant to take any injections. What agent would you recommend? Please provide the trade name, generic name, the dose you would start the patient with frequency, and route. Metformin, a biguanide product, is the main-line drug suggested for the medical therapy of type 2 diabetes; it was uncovered in 1922 and launched as a corrective agent in 1957. In a study probing the result of metformin on problems in overheavy patients with type 2 diabetes, metformin reduced the occurrence of cardiovascular measures and entirely-reason mortality in patients with diabetes when associated with insulin-treated patients [28], spreading the existence of diabetic patients by 38% (Hu et al. 2021). Generic Name Metformin Glucophage, Fortamet, Glumetza, Trade Name Glucophage XR, Riomet Initial Dose 250 mg Frequency Twice Daily Route Oral Insulin Response Enhancers Drug Class Biguanides C. What are the contraindications of your selected diabetic therapy? These contain renal impairment with higher serum creatine levels (more than 136 mmol/l in men and 124 mmol/l in women), unusual creatinine clearance, congestive heart failure needing pharmacologic therapy, and advanced age 80 years of age (Mestrovic 2021). Renal impairment signifies a contraindication to metformin use owing to the raised risk of lactic acidosis, a method of metabolic acidosis due to the insufficient clearance of lactic acid from the blood. Congestive heart failure usually has deemed a contraindication for metformin medication. Thus the drug is withdrawn from enormous numbers of patients with type 2 diabetes and concurrent cardiac failure. The prescription label declares that metformin therapy should not be launched in patients older than 80, except their creatinine clearance is standard.

Still, numerous findings of patients with type 2 diabetes, involving those over 70 years of age, have indicated that metformin therapy is not linked with considerably raised plasma lactate levels (Mestrovic 2021). D. What lab workup should you obtain? What sort of results will you see in patients who have hypothyroidism and hyperthyroidism? Test Name Hypothyroidism Hyperthyroidism TSH A high TSH level indicates that the thyroid gland is not making enough thyroid hormone. TSH level is low, usually indicates that the thyroid is producing too much thyroid hormone T4 elevated TSH and low FT4 low TSH with an elevated or FTI FT4 or FTI T3 high TSH and low FT4 or Low TSH, only the T3 is FTI, but have a standard elevated, and the FT4 or T3 FTI is normal. Thyroid Antibody Test Radioactive iodine uptake positive anti-thyroid peroxidase and antithyroglobulin antibodies a low RAIU is seen when the thyroid gland is underactive thyrotropin receptor antibody test (TSHR or TRAb) A very high RAIU is seen in individuals whose thyroid gland is overactive E. What is the treatment of choice for hypothyroidism? What is the mechanism of action? Please provide the initial dose, trade, and generic name of the drug, route, and frequency? Generic Name Trade Name Initial Dose Route of Administration Frequency Mechanism of Action Levothyroxine Sodium Synthroid, Levoxyl, L Thyroxine, Levo T, Levothroid, Levothyroxine T4, Levoxine, Tirosint, Unithroid 12.5 mcg Orally Once, in the morning, 30 minutes before a meal a synthetic version of the body’s natural thyroid hormone: thyroxine; thyroid hormones work by directly affecting DNA copy to boost body absorption by enhancing gluconeogenesis, protein synthesis, the utilization of glycogen stores, and other functions. F. What are the adverse effects, and what important teaching will you provide this patient on thyroid replacement therapy? Thyroid replacement hormones are typically highly accepted. Symptoms during therapy are frequently due to harmful, high levels of thyroid hormones and subsequent indications from hyperthyroidism. Signs may contain chest pain, heightened heart rate or pulse rate, extreme sweating, heat intolerance, nervousness, headache, insomnia, diarrhea, vomiting, weight loss, and fever. Some women may encounter unusual menstrual cycles (Williams & Marks 2021). To ensure that your thyroid hormone replacement works properly, consider the following recommendations: Retain routine appointments with a healthcare worker. Take thyroid medicine at a minimum of 1 hour before mealtime and any calcium or iron pills you might need. Or get at bedtime, or at a minimum of 3 hours later than eating or taking any calcium or iron medicines. Inform health care workers of your thyroid hormone therapy before starting medication for every other illness. Specific therapies for more disorders or diseases can impact the amount of thyroid hormone treatment. Inform your healthcare worker of some new indications that may arise. Know all healthcare providers of your thyroid condition and medicine dosage. References: Castro, Regina M (2021). GLP-1 agonists diabetes drugs and weight loss. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/type-2diabetes/expert-answers/byetta/faq-20057955 Einhorn, Daniel (2019). Diabetes Medicines That Help Your Waistline and Your Heart. Taking control of your diabetes. https://tcoyd.org/2019/03/diabetes-medicines-that-helpyour-waistline-and-your-heart/ Hu, D., Xie, F., Xiao, Y., Lu, C., Zhong, J., Huang, D., Chen, J., Wei, J., Jiang, Y., & Zhong, T. (2021). Metformin: A Potential Candidate for Targeting Aging Mechanisms. Aging and Disease, 12(2), 480– 493. https://doi.org/10.14336/AD.2020.0702 Mestrovic, Tomislav (2021). Metformin Contraindications. News Medical Life Sciences. https://www.news-medical.net/health/MetforminContraindications.aspx Robinson, Marcene (2021). The anti-diabetic drug causes double the weight loss of competitors. UB Now. http://www.buffalo.edu/ubnow/stories/2021/07/diabetesdrugs-weight-loss.

html Rope, Kate., & Dansinger, Michael (2020). What Are SGLT2 Inhibitors? https://www.webmd.com/diabetes/sglt2-inhibitorsoverview Williams, Eni & Marks, Jay W. (2021). Thyroid Replacement Hormones. MedicineNet. https://www.medicinenet.com/thyroid_replacementoral/article.htm#what_are_thyroid_replacement_hormones_and_how _do_they_work CLICK HERE TO GET A PROFESSIONAL WRITER TO WORK ON THIS PAPER AND OTHER SIMILAR PAPERS CLICK THE BUTTON TO MAKE YOUR ORDER

[manibolly]

Uh oh, somebody's eating something they're not supposed to! I think he's a type 2 diabetic like me. I also think he has to take glucophage like I do. I also think that's why he lost so much weight.

[sehat86]

How long does glucophage/Metformin stay in your system?

https://www.drugs.com/medical-answers/how-long-does-glucophage-metformin-stay-in-system-269979/