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iikciim · 1 month ago

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Biologic Response–Modifying and Antirheumatic Drugs

Anatomy, Physiology, and Pathophysiology Overview

Overview of Immunomodulators

Cancer treatment has traditionally involved surgery, radiation, and chemotherapy.

Surgery and radiation are usually local or regional therapies. Chemotherapy is generally systemic, but it often does not completely eliminate all of the cancer cells in the body. Adjuvant therapy is frequently used to destroy undetected distant micrometastases.

The two major components of the body’s immune system are humoral immunity, mediated by B-cell functions (primarily antibody production), and cell-mediated immunity, which is mediated by T-cell functions. The humoral and cellular immune systems act together to recognize and destroy foreign particles and cells in the blood or other body tissues. The humoral immune system is composed of lymphocytes that are known as B cells until they are transformed into plasma cells when they come in contact with an antigen (foreign substance). The plasma cells then manufacture antibodies to that antigen.

Over the last two decades, medical technology has developed a group of drugs impacting the immune system, and a new addition to these drugs includes the biologic response-modifying drugs or biologic response modifiers (BRMs).

These drugs alter the body’s response to diseases such as cancer and autoimmune, inflammatory, and infectious diseases and can enhance or restrict the patient’s immune response to disease, can stimulate a patient’s hematopoietic function, and prevent disease.

Biologic response–modifying drugs provide another treatment option for patients who have malignancies and/or are receiving chemotherapy and need to boost blood cell counts.

Two broad classes of biologic response–modifying drugs are hematopoietic drugs and immunomodulating drugs. Subclasses of immunomodulating drugs include interferons, monoclonal antibodies, interleukin receptor agonists and antagonists, and miscellaneous drugs. Disease-modifying antirheumatic drugs are drugs used to treat rheumatoid arthritis.

Immunomodulating drugs therapeutically alter a patient’s immune response.

An intact immune system can identify cells as malignant and destroy them; a healthy immune system can distinguish between tumor cells and normal body tissues.

People develop cancerous cells in their bodies on a regular basis; normally the immune system is able to eliminate these cells before they multiply to uncontrollable levels. Only when the natural immune responses fail to keep pace with these initially microscopic cancer cell growths does a person develop a true “cancer” requiring clinical intervention.

Biologic response–modifying drugs work by one of three mechanisms: (1) enhancement or restoration of the host’s immune system defenses against the tumor; (2) direct toxic effect on the tumor cells, which causes them to lyse, or rupture; or (3) adverse modification of the tumor’s biology, which makes it harder for the tumor cells to survive and reproduce.

Some immunomodulating drugs are used to treat autoimmune, inflammatory, and infectious diseases. They either reduce the patient’s inappropriate immune response (as in rheumatoid arthritis) or strengthen the immune response against microorganisms and cancer cells.

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Immune System

Tumor cells express chemical compounds on their surfaces that signal the immune system that these cells are a threat. These chemical markers are called tumor antigens or markers.

An antigen is any substance that the body’s immune system recognizes as foreign. Recognition of antigens varies among individuals, which is why some people are more prone than others to immune-related diseases such as allergies, inflammatory diseases, and cancer.

Humoral immunity is mediated by B-cell functions (primarily antibody production), and cell-mediated immunity is mediated by T-cell functions.

Attack against tumor cells by antibodies produced by the B lymphocytes of the humoral immune system prepares those tumor cells for destruction by the T lymphocytes.

The immune system in a healthy individual is genetically preprogrammed to be able to mount an antibody response against literally millions of different antigens resulting from the individual’s lifetime antigen exposure and through exposure to new antigens passed down.

Antibodies that a single plasma cell makes are all identical and are called monoclonal.

Monoclonal antibodies have also been prepared synthetically using recombinant DNA technology, which has resulted in newer drug therapies.

When B lymphocytes differentiate into plasma cells, some of these B cells become memory cells that “remember” the exact characteristics of a particular foreign antigen, allowing a stronger and faster immune response in re-exposure to the same antigen.

The functional cells of the cell-mediated immune system are the T lymphocytes, which mature in the thymus. T cells include cytotoxic T cells, T helper cells, and T suppressor cells.

Cytotoxic T cells directly kill their targets by causing cell lysis or rupture.

T helper cells are considered the master controllers of the immune system. They direct the actions of many other immune components, such as lymphokines and cytotoxic T cells.

Cytokines are non-antibody proteins serving as chemical mediators of physiologic functions.

Lymphokines are a subset of cytokines released by T lymphocytes upon contact with antigens; they serve as chemical mediators of the immune response.

T suppressor cells have an effect on the immune system that is opposite to that of T helper cells and serve to limit or control the immune response. A healthy immune system has about twice as many T helper cells as T suppressor cells at any given time.

The cancer-killing cells of the cellular immune system are the macrophages (derived from monocytes), natural killer (NK) cells (another type of lymphocyte), and polymorphonuclear leukocytes (not lymphocytes), which are also called neutrophils.

In contrast, T suppressor cells have an important negative influence on antitumor actions of the immune system. Overactive T suppressor cells may be responsible for clinically significant cancer cases by permitting tumor growth beyond the immune system’s control.

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Pharmacology Overview

Therapeutic effects of the biologic response-modifying drugs include enhancement of hematopoietic function, regulation or enhancement of the immune response, inhibition of metastases, prevention of cell division, or inhibition of cell maturation.

Fingolimod (Gilenya) is a newer oral drug for the treatment of relapsing forms of MS to reduce the frequency of clinical exacerbations and delay disability progression. It is a sphingosine 1-phosphate receptor modulator.

Hematopoietic Drugs

Erythropoietic drugs (epoetin alfa and darbepoetin alfa), three colony-stimulating factors (filgrastim, pegfilgrastim, and sargramostim) promote the synthesis of various types of major blood components by promoting the growth, differentiation, and function of their corresponding precursor cells in the bone marrow.

All hematopoietic drugs decrease the duration of chemotherapy-induced anemia, neutropenia, and thrombocytopenia and allow higher dosages of chemotherapy to be given; decrease bone marrow recovery time after bone marrow transplantation or irradiation; and stimulate other cells in the immune system to destroy or inhibit the growth of cancer cells, as well as virus- or fungus-infected cells.

All of these drugs are produced by recombinant DNA technology, which allows them to be essentially identical to their endogenously produced counterparts.

Neutrophils are the most important granulocytes for fighting infection. Colony-stimulating factors stimulate neutrophils to grow and mature and thus directly oppose the detrimental bone marrow actions of chemotherapy.

Colony-stimulating factors also enhance the functioning of mature cells of the immune system, such as macrophages and granulocytes. This increases the ability of the body’s immune system to kill cancer cells, as well as virus- and fungus-infected cells.

The effect of hematopoietic drugs on the bone marrow cells also reduces the recovery time after bone marrow transplantation and radiation therapy.

Filgrastim and sargramostim have significant drug interactions when these two drugs are given with myelosuppressive antineoplastic drugs. When myelosuppressive antineoplastics are given with them, the drugs directly antagonize each other. Filgrastim and sargramostim are not given within 24 hours of administration of myelosuppressive antineoplastics.

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Interferons

Interferons are proteins with three basic properties: antiviral, antitumor, and immunomodulating. There are three different groups of interferon drugs—the alpha, beta, and gamma interferons—each with its own antigenic and biological activity.

Interferons are most commonly used in the treatment of certain viral infections and types of cancer.

Interferons are recombinantly manufactured substances that are identical to the interferon cytokines that are naturally present in the human body.

Overall, interferons have three different effects on the immune system. They can (1) restore its function if it is impaired, (2) augment (amplify) the immune system’s ability to function as the body’s defense, and (3) inhibit the immune system, useful when the immune system has become dysfunctional, causing autoimmune disease such as multiple sclerosis.

The beneficial actions of interferons make them excellent drugs for the treatment of viral infections, various cancers, and some autoimmune disorders.

The most commonly used interferon products are in the alfa class and are referred to as leukocyte interferons because they are produced from human leukocytes. Two newer types of interferon alfa include peginterferon alfa-2a and peginterferon alfa-2b.

Contraindications to the use of interferons include known drug allergy and may include autoimmune disorders, hepatitis or liver failure, concurrent use of immunosuppressant drugs, Kaposi’s sarcoma related to AIDS, and severe liver disease.

The most common adverse effects can be broadly described as flulike symptoms: fever, chills, headache, malaise, myalgia, and fatigue.

The major dose-limiting adverse effect of interferons is fatigue.

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Monoclonal Antibodies

Monoclonal antibodies are becoming the standard of therapy in many areas, including the treatment of cancer, rheumatoid arthritis and other inflammatory diseases, multiple sclerosis, and organ transplantation. They can specifically target cancer cells with minimal effect on healthy cells.

The mab suffix in a drug name is usually an abbreviation for “monoclonal antibody.”

The FDA recently approved biosimilar products to infliximab (Inflectra), etanercept (Ereizi), and adalimumab (Amjevita).

Vedolizumab (Entyvio) was approved in 2014 for the treatment of Crohn’s disease and ulcerative colitis. The most common side effects are nausea, nasopharyngitis, upper respiratory tract infection, arthralgia, pyrexia, fatigue, headache, cough, and infusion-related reactions.

Patients receiving these very potent drugs can manifest acute symptoms that are comparable to classic allergy or flulike symptoms, such as fever, dyspnea, and chills.

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Interleukins and Related Drugs

Interleukins are a natural part of the immune system and are classified as lymphokines.

Lymphokines are soluble proteins that are released from activated lymphocytes such as natural killer cells.

Interleukins cause multiple effects on the immune system, one of which is antitumor action.

Aldesleukin was previously indicated only for the treatment of metastatic renal cell carcinoma. It is now also approved for the treatment of metastatic melanoma.

Denileukin diftitox is currently indicated only as therapy for a skin-based lymphoma known as cutaneous T-cell lymphoma, which often metastasizes to other areas of the body.

Anakinra and tocilizumab are indicated for symptom control in patients with rheumatoid arthritis for whom other therapy has failed.

Therapy with aldesleukin is commonly complicated by severe toxicity. A syndrome known as capillary leak syndrome is responsible for the severe toxicities of aldesleukin.

Common adverse effects associated with denileukin diftitox administration are GI upset, hypoalbuminemia, elevated liver enzyme levels, edema, dyspnea, cough, fever, chills, asthenia, generalized pain, chest pain, infection, and headache.

Anakinra has a much milder adverse effect profile that includes local reactions at the injection site, various respiratory tract infections, and headaches.

Tocilizumab has a high risk of causing anaphylaxis.

The most common side effects of ixekizumab are neutropenia, immunogenicity, infection, and injection site reactions.

Some additional medications can be broadly classified as miscellaneous immunomodulating drugs. A special term for immunostimulant drugs that are nonspecific is adjuvant.

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Pathophysiology Overview

Rheumatoid Arthritis

Rheumatism is a general term for any of several disorders characterized by inflammation, degeneration, or metabolic derangement of connective tissue structures, especially joints and related structures such as muscles, tendons, bursae, fibrous tissue, and ligaments.

Rheumatoid arthritis is a chronic autoimmune disorder that commonly causes inflammation and tissue damage in joints. It can also cause anemia and diffuse inflammation in the lungs, eyes, and pericardium of the heart, and subcutaneous nodules under the skin.

Disease-modifying antirheumatic drugs (DMARDs) not only provide antiinflammatory and analgesic effects, but they can arrest or slow the disease processes associated with arthritis.

They exhibit anti-inflammatory, antiarthritic, and immunomodulating effects and work by inhibiting the movement of various cells into an inflamed, damaged area, such as a joint.

DMARDs often have a slow onset of action of several weeks versus minutes to hours for NSAIDs; sometimes these drugs are also referred to as slow-acting antirheumatic drugs (SAARDs).

They were previously thought of as second-line drugs for the treatment of arthritis because they can have much more toxic adverse effects than do the NSAIDs. The American College of Rheumatology updated its treatment guidelines in 2012 and again in 2015, and now recommends the use of DMARDs as first-line therapy in many patients.

Nonbiologic DMARDs include methotrexate, leflunomide, hydroxychloroquine, and sulfasalazine.

The biologic DMARDs include adalimumab, anakinra, certolizumab, etanercept, golimumab, infliximab, adalimumab, abatacept, rituximab, tocilizumab and, most recently, tofacitinib.

Tofacitinib (Xeljanz) is a drug of the Janus kinase inhibitor (JAK) class for adult patients with moderately to severely active RA with an inadequate response or intolerance to methotrexate. However, serious infections including TB and other infections are concerns with the use of the drug and the patient needs to know the signs and symptoms to report to the prescriber. Similar drugs include baricitinib (Olumiant), fedratinib (Inrebic), ruxolitinib (Jakafi) and upadacitinib (Rinvoq). This class of drugs is given orally.

DMARDs are not used in patients with active bacterial infection, active herpes zoster, active or latent tuberculosis, or acute or chronic hepatitis B or C.

Etanercept, infliximab, and adalimumab are not to be used in patients with heart failure, lymphoma, or multiple sclerosis.

Methotrexate and leflunomide are to be avoided during pregnancy and lactation.

The recommended therapy with nonbiologic DMARDs usually begins with methotrexate or leflunomide for most patients.

Biologic DMARDs are generally reserved for those patients whose disease does not respond to methotrexate or leflunomide. The biologic DMARDs include etanercept, infliximab, adalimumab, abatacept, and rituximab.

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Pathophysiology Overview

Rheumatoid Arthritis

Rheumatoid arthritis is a chronic autoimmune disorder that commonly causes inflammation and tissue damage in joints. It can also cause anemia and diffuse inflammation in the lungs, eyes, pericardium of the heart, and subcutaneous nodules under the skin.

Disease-modifying antirheumatic drugs (DMARDs) not only provide anti-inflammatory and analgesic effects, but they can arrest or slow the disease processes associated with arthritis.

They exhibit anti-inflammatory, antiarthritic, and immunomodulating effects and work by inhibiting the movement of various cells into an inflamed, damaged area, such as a joint.

DMARDs often have a slow onset of action of several weeks versus minutes to hours for NSAIDs; sometimes these drugs are also referred to as slow-acting antirheumatic drugs (SAARDs).

They were previously thought of as second-line drugs for the treatment of arthritis because they can have much more toxic adverse effects than NSAIDs. The American College of Rheumatology updated its treatment guidelines in 2012 and again in 2015, and now recommends the use of DMARDs as first-line therapy in many patients.

Nonbiologic DMARDs include methotrexate, leflunomide, hydroxychloroquine, and sulfasalazine.

The biologic DMARDs include adalimumab, anakinra, certolizumab, etanercept, golimumab, infliximab, adalimumab, abatacept, rituximab, tocilizumab and, most recently, tofacitinib.

Tofacitinib (Xeljanz) is a drug of the Janus kinase inhibitor (JAK) class for adult patients with moderately to severely active RA with an inadequate response or intolerance to methotrexate. However, serious infections including TB and other infections are concerns with the use of the drug and the patient needs to know the signs and symptoms to report to the prescriber. Similar drugs include baricitinib (Olumiant), fedratinib (Inrebic), ruxolitinib (Jakafi), and upadacitinib (Rinvoq). This class of drugs is given orally.

DMARDs are not used in patients with active bacterial infection, active herpes zoster, active or latent tuberculosis, or acute or chronic hepatitis B or C.

Etanercept, infliximab, and adalimumab are not to be used in patients with heart failure, lymphoma, or multiple sclerosis.

Methotrexate and leflunomide are to be avoided during pregnancy and lactation.

The recommended therapy with nonbiologic DMARDs usually begins with methotrexate or leflunomide for most patients.

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Nursing Process

Nursing management associated with the administration of biological response–modifying drugs focuses on the use of careful aseptic technique and other measures to prevent infection; proper nutrition; oral hygiene; monitoring of blood counts; and management of adverse effects, including joint and bone pain and flulike symptoms.

Before administering these medications, document a baseline assessment of the following: vital signs, skin turgor and intactness, bowel sounds and patterns, and breath sounds.

Assess potential intravenous and subcutaneous sites, and, if appropriate, note chemotherapy-induced absolute neutrophil nadir (low point).

With the use of filgrastim, assess for any existing joint or bone pain because of the possible adverse effects of mild to severe bone pain with filgrastim.

Do not administer filgrastim and sargramostim within 24 hours of a myelosuppressive antineoplastic, and follow the time frame for their use (as prescribed), whether in an inpatient or home setting.

With biological response-modifying drugs, assess the patient for the presence of any conditions that represent contraindications or cautions to their administration.

Assess the following systems: (1) respiratory system with attention to rate, rhythm, and depth as well as breath sounds, listening for any adventitious (abnormal) sounds; (2) cardiac system with attention to vital signs, heart sounds, heart rate and rhythm, and oxygen saturation levels, as well as assessment for edema and/or shortness of breath, presence of cyanotic discoloration around the mouth or nail beds, and any chest pain; (3) central nervous system with a focus on baseline mental status, as well as assessment for any seizure-like activity or central nervous system abnormalities; and (4) immune system, noting any history of chronic illnesses, ability to fight off infections, and history of suppressed immunity.

Before interferons are given, assess the patient’s history of drug allergies as well as any history of autoimmune disorders, hepatitis, liver failure, or AIDS.

Monitor the patient for capillary leak syndrome (CLS) if they are taking interleukins. Identification of early symptoms will allow critical, supportive treatment with discontinuation of the interleukin drug. Assess for drug allergy as well as contraindications of organ transplantation and abnormal thallium cardiac stress testing results or abnormal pulmonary function tests.

The recommended therapy with nonbiologic DMARDs usually begins with methotrexate or leflunomide for most patients. Biologic DMARDs are generally reserved for those patients whose disease does not respond to methotrexate or leflunomide. The biologic DMARDs include etanercept, infliximab, adalimumab, abatacept, and rituximab. Assess for contraindications to the use of DMARDs, such as active bacterial infections, active herpes, active/latent tuberculosis, and acute or chronic hepatitis B or C.

Before initiation of therapy with leflunomide, perform a complete assessment of hepatic functioning as well as baseline blood cell counts. Because of the possible adverse effects of diarrhea and respiratory infections, assess GI functioning and bowel patterns.

Etanercept is to be avoided in those with sepsis and active infections, so conduct a thorough assessment of white blood cell (WBC) counts and for any signs and symptoms of infection, or a history of infection. Some dosage forms may contain latex; it is critical to also assess for latex allergy.

Premedication with acetaminophen and diphenhydramine may be deemed necessary to help minimize any allergic-type reaction when any of the biological response-modifying drugs are administered.

With some of the biological response-modifying drugs, treatment with opioids, other antihistamines, and/or anti-inflammatory drugs may be required for the management of bone pain and chills if treatment with acetaminophen or diphenhydramine is not successful.

Antiemetics may also be needed for any drug-related nausea or vomiting and may be given before the administration of the specific biological response-modifying drug.

With concerns of infection, as with many of the biologic response-modifying drugs, monitor the patient’s vital signs with attention to temperature and also for the occurrence of chills and headaches.

With monoclonals, serious infections are a major concern.

Therapeutic responses to biologic response–modifying drugs include a variety of responses, such as a decrease in the growth of the lesion or mass, decreased tumor size, and an easing of symptoms related to the tumor or disease process. Other therapeutic effects are an improvement in WBC, red blood cell (RBC), platelet counts, and/or a return of blood counts to normal levels, and absence of infection, anemias, and hemorrhage.

DMARDs are expected to have therapeutic results within a documented time frame (often weeks) with the patient experiencing increased ability to move joints, less discomfort, and an overall increased sense of improvement and well-being.

The toxicity of these drugs may be manifested by liver, renal, and respiratory dysfunction and, for methotrexate, bone marrow suppression.

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healthfile24 · 1 year ago

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guesthypebusinessfinance · 2 years ago

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The next dialogue and evaluation of our monetary situation and outcomes of operations must be learn along side our condensed consolidated monetary statements and the associated notes to these statements included elsewhere on this Quarterly Report on Type 10-Q. Along with historic monetary info, the next dialogue and evaluation comprises forward-looking statements that contain dangers, uncertainties and assumptions. A few of the numbers included herein have been rounded for the comfort of presentation. Our precise outcomes might differ materially from these anticipated in these forward-looking statements because of many components, together with these mentioned underneath "Danger Components" in our Annual Report on Type 10-Ok for the fiscal 12 months ended December 31, 2022 and on this Quarterly Report on Type 10-Q. Overview Foghorn is a medical stage, precision therapeutics biotechnology firm pioneering a brand new class of medicines that deal with severe illnesses by correcting irregular gene expression by means of selectively focusing on the chromatin regulatory system, an untapped alternative for therapeutic intervention in oncology and in a large spectrum of different illnesses together with virology, autoimmune illnesses and neurology. The chromatin regulatory system orchestrates gene expression-the turning on and off of genes-which is key to how all our cells operate. The chromatin regulatory system is implicated in roughly 50% of all cancers, and understanding how this method works may result in a completely new class of precision medicines. To our data, we're the one firm with the power to review and goal the chromatin regulatory system at scale, in context, and in an built-in method. Our proprietary Gene Site visitors Management® platform offers an built-in and mechanistic understanding of how the assorted elements of the chromatin regulatory system work together, permitting us to determine, validate and probably drug targets inside this method. We have now developed distinctive capabilities which have yielded new insights and scalability in drugging this new, beforehand untapped and promising space. Since our inception in 2015, our platform has generated a broad pipeline of extra than a dozen packages with two clinical-stage drug candidates at the moment in part 1 improvement throughout a number of indications. We have now found extremely selective chemical matter for a few of the most difficult targets in oncology together with BRM, CBP, EP300 and ARID1B in addition to different undisclosed targets. We imagine our present pipeline has the potential to assist greater than 500,000 most cancers sufferers. We take a small molecule modality agnostic method to drugging targets which contains protein degraders, allosteric enzymatic inhibitors, and transcription issue disruptors. We're a biology first firm which suggests we focus first on the underlying genetics and biology of a illness related goal after which leverage essentially the most acceptable drugging method to impression the illness biology. Our lead clinical-stage candidate, FHD-286, a selective, allosteric ATPase inhibitor is being developed in separate Part 1 research in (i) metastatic uveal melanoma and (ii) relapsed and/or refractory acute myeloid leukemia ("AML"), and myelodysplastic syndrome ("MDS"). We anticipate preliminary medical information for metastatic uveal melanoma within the second quarter of 2023. The relapsed and/or refractory AML and MDS examine has been positioned on full medical maintain by the FDA attributable to potential differentiation syndrome and we plan to offer a regulatory replace within the second quarter of 2023. On April twenty fourth, 2023, we supplied an replace on the FHD-609 Part 1 program in synovial sarcoma and SMARCB1-deleted tumors. We have now paused enrollment within the FHD-609 examine attributable to a grade 4 QTc prolongation occasion in a synovial sarcoma affected person on the second highest dose being evaluated. Enrollment of the dose

escalation portion of the examine has been accomplished and a most tolerated dose has been recognized. Consequently, the FDA positioned the examine on partial medical maintain, whereas permitting sufferers at the moment enrolled and benefiting from remedy to proceed dosing and to stay on FHD-609. The Firm isn't, at the moment, planning to pursue a dose enlargement examine independently. We imagine Foghorn has the potential to be a serious biopharmaceutical firm with our present pipeline addressing greater than 20 tumor varieties impacting extra than 500,000 new sufferers yearly. We imagine we now have the potential to file at least six new INDs over the following 4 years. Since our inception, we now have centered considerably all of our sources on constructing our Gene Site visitors Management platform, organizing and staffing our firm, enterprise planning, elevating capital, conducting discovery and analysis actions, defending our commerce secrets and techniques, submitting patent purposes, figuring out potential product candidates, enterprise preclinical research and medical trial actions, establishing preparations with third events for the manufacture of preliminary portions of our product candidates and element supplies and initiating two strategic collaborations. We do not need any merchandise accepted on the market and haven't generated any income from product gross sales. On December 10, 2021, we entered right into a collaboration settlement (the "Lilly Collaboration Settlement") with Eli Lilly and Firm ("Lilly"), for which we obtained an upfront fee of $300.0 million in January 2022 (see Be aware 8 to our notes to unaudited condensed consolidated monetary statements included elsewhere on this Quarterly Report on Type 10-Q). Concurrent with the Lilly Collaboration Settlement, we additionally entered right into a inventory buy settlement (the "Lilly SPA") and issued and bought 13 -------------------------------------------------------------------------------- Desk of Contents Lilly 4,000,000 shares of our frequent inventory at a value of $20.00 per share, leading to internet proceeds of $80.0 million, of which $42.2 million was allotted to fairness upon the issuance of the Firm's frequent inventory. Within the third quarter of 2022, the Firm achieved a analysis milestone associated to a Analysis Collaboration and Unique License Settlement (the "Merck Collaboration Settlement") with Merck Sharp & Dohme Corp. ("Merck") and obtained a $5.0 million milestone fee from Merck. We have now incurred vital working losses since our inception. For the three months ended March 31, 2023 and the 12 months ended December 31, 2022, we reported internet losses of $30.5 million and $108.9 million, respectively. As of March 31, 2023, we had an collected deficit of $403.6 million. We anticipate to proceed to incur vital bills and growing working losses for a minimum of the following a number of years. Our means to generate any product income or product income ample to realize profitability will depend upon the profitable improvement and eventual commercialization of a number of product candidates we're creating and will develop. We anticipate that our bills and capital necessities will enhance considerably in reference to our ongoing actions, notably if and as we: • advance our FHD-286 product candidate and proceed our preclinical improvement of product candidates from our present analysis packages; • determine and advance further analysis packages and extra product candidates; • provoke preclinical testing for any new product candidates we determine and develop; • acquire, preserve, develop, implement, defend and shield our commerce secrets and techniques and mental property portfolio and supply reimbursement of third-party bills associated to our patent portfolio; • rent further analysis and improvement personnel; • add operational, authorized, compliance, monetary and administration info

techniques and personnel to assist our analysis, product improvement and operations; • develop the capabilities of our platform; • purchase or in-license product candidates, mental property and applied sciences; • function as a public firm; • search advertising approvals for any product candidates that efficiently full medical trials; and • finally set up a gross sales, advertising and distribution infrastructure to commercialize any merchandise for which we might acquire advertising approval. We won't generate income from product gross sales except and till we efficiently commercialize one in every of our product candidates, after finishing medical improvement and acquiring regulatory approval. If we acquire regulatory approval for any of our product candidates, we anticipate to incur vital bills associated to creating our commercialization functionality to assist product gross sales, advertising, manufacturing and distribution. Additional, we anticipate to incur further prices related to working as a public firm. In consequence, we are going to want substantial further funding to assist our persevering with operations and pursue our progress technique. Till we are able to generate vital income from product gross sales, if ever, we anticipate to finance our operations by means of a mix of fairness choices, debt financings and collaborations or licensing preparations and our collaboration agreements with Merck and Lilly. We could also be unable to boost further funds or enter into such different agreements or preparations when wanted on favorable phrases, or in any respect. If we fail to boost capital or enter into such agreements as, and when, wanted, we might must considerably delay, cut back our improvement or commercialization plans for a number of of our product candidates. Due to the quite a few dangers and uncertainties related to pharmaceutical product improvement, we're unable to precisely predict the timing or quantity of elevated bills or when, or if, we will obtain or preserve profitability. Even when we're capable of generate product gross sales, we might not develop into worthwhile. If we fail to develop into worthwhile or are unable to maintain profitability on a unbroken foundation, then we could also be unable to proceed our operations at deliberate ranges and be pressured to cut back or terminate our operations. 14 -------------------------------------------------------------------------------- Desk of Contents Parts of Our Outcomes of Operations Collaboration Income So far, we now have not generated any income from product gross sales and don't anticipate to take action within the close to future. If our improvement efforts for our product candidates are profitable and end in regulatory approval or licenses with third events, we might generate income sooner or later from product gross sales, milestone funds underneath our present collaboration agreements or funds from different license agreements that we might enter into with third events. In December of 2021, we entered right into a strategic collaboration with Lilly to create novel oncology medicines by making use of Foghorn's proprietary Gene Site visitors Management platform. The collaboration features a co-development and co-commercialization settlement for the aforementioned selective BRM oncology program and an extra undisclosed oncology goal. As well as, the collaboration contains three further discovery packages utilizing Foghorn's proprietary Gene Site visitors Management platform. Underneath the phrases of the collaboration, Foghorn obtained upfront consideration of $300.0 million in money pursuant to the Lilly Collaboration Settlement, along with an fairness funding by Lilly of $80.0 million in shares of Foghorn frequent inventory pursuant to the Lilly SPA. For the BRM-selective program and the extra undisclosed goal program, Foghorn will lead discovery and early analysis actions, whereas Lilly will lead

improvement and commercialization actions with participation from Foghorn in operational actions and value sharing. Foghorn and Lilly will share 50/50 in the U.S. economics, and Foghorn is eligible to obtain royalties on ex-U.S. gross sales beginning within the low double-digit vary and escalating into the twenties primarily based on income ranges. For the extra discovery packages, Foghorn will lead discovery and early analysis actions. Foghorn might obtain as much as a complete of $1.3 billion in potential improvement and commercialization milestones. Moreover, Foghorn can have an choice to take part in a share of the U.S. economics and is eligible to obtain tiered royalties from the mid-single digit to low-double digit vary on gross sales exterior the U.S. that could be exercised after the profitable completion of the dose-finding toxicity research. We can't present assurances as to the timing of future milestones, royalty funds and economics related to the strategic collaboration with Lilly. We acknowledged complete deferred income of $337.8 million associated to the Lilly Collaboration Settlement and the Lilly SPA, which included the $300.0 million upfront fee underneath the Lilly Collaboration Settlement in addition to $37.8 million allotted to deferred income from the gross proceeds of the Lilly SPA to be acknowledged over the efficiency interval. In the course of the three months ended March 31, 2023, we acknowledged $4.7 million and $3.8 million, respectively, of income underneath the Lilly Collaboration Settlement and, as of March 31, 2023, we had $315.1 million of deferred income associated to the above talked about upfront fee and income allocation remaining on our condensed consolidated steadiness sheets. In July 2020, we entered into the Merck Collaboration Settlement, pursuant to which we are going to apply our proprietary Gene Site visitors Management platform to find and develop novel therapeutics. Underneath the Merck Collaboration Settlement, we granted Merck unique international rights to develop and commercialize medication that goal dysregulation of a single transcription issue. Underneath the phrases of the Merck Collaboration Settlement, we obtained a nonrefundable upfront fee of $15.0 million from Merck, and are eligible to obtain as much as $245.0 million upon achievement of specified analysis, improvement and regulatory milestones by any product candidate generated by the collaboration, and as much as $165.0 million upon achievement of specified sales-based milestones per accepted product from the collaboration, if any, in addition to royalties on gross sales of any accepted product from the collaboration. We can't present assurance as to the timing of future milestone or royalty funds or that we are going to obtain any of those funds at all. For the three months ended March 31, 2023 and 2022, we acknowledged $0.6 million and $0.1 million of income underneath the Merck Collaboration Settlement. Within the third quarter of 2022, the Firm achieved a analysis milestone associated to the Merck Collaboration Settlement and obtained a $5.0 million milestone fee from Merck. As of March 31, 2023, we had $16.4 million of deferred income associated to the upfront fee and milestone achievement remaining on our condensed consolidated steadiness sheets. Working Bills Our working bills are comprised of analysis and improvement bills and normal and administrative bills. Analysis and Improvement Bills Analysis and improvement bills consist primarily of prices incurred for our analysis actions, together with our discovery efforts, and progressing our packages, which embody: •personnel-related prices, together with salaries, advantages and stock-based compensation expense, for workers engaged in analysis and improvement capabilities; 15 -------------------------------------------------------------------------------- Desk of Contents •bills incurred in reference to our analysis packages and preclinical and

medical improvement of our product candidates, together with underneath agreements with third events, akin to consultants and contractors and contract analysis organizations ("CROs'); •the price of manufacturing drug substance and drug product to be used in our analysis and preclinical research and medical trials underneath agreements with third events, akin to consultants and contractors and contract improvement and manufacturing organizations ("CDMOs)"; •laboratory provides and analysis supplies; •amenities, depreciation and amortization and different bills, which embody direct and allotted bills for hire and upkeep of amenities and insurance; and •funds made underneath third-party licensing agreements. We observe our direct exterior analysis and improvement bills on a program-by-program foundation. These include prices that embody charges, reimbursed supplies, and different prices paid to consultants, contractors, CDMOs, and CROs in reference to our preclinical, medical and manufacturing actions. We do not allocate worker prices, prices related to our discovery efforts, laboratory provides, and amenities bills, together with depreciation or different oblique prices, to particular product improvement packages as a result of these prices are deployed throughout a number of packages and our platform and, as such, will not be individually categorised. We anticipate that our analysis and improvement bills will enhance considerably as we advance our packages into medical improvement and develop our discovery, analysis and preclinical actions within the close to time period and sooner or later. At this time, we can't precisely estimate or know the character, timing and prices of the efforts that will likely be obligatory to finish the preclinical and medical improvement of any product candidates we might develop. A change within the end result of any variety of variables with respect to product candidates we might develop may considerably change the prices and timing related to the event of that product candidate. We might by no means reach acquiring regulatory approval for any product candidates we might develop. Basic and Administrative Bills Basic and administrative bills consist primarily of personnel-related prices, together with salaries, advantages and stock-based compensation, for workers engaged in govt, authorized, finance and accounting and different administrative capabilities. Basic and administrative bills additionally embody skilled charges for authorized, patent, consulting, investor and public relations, human sources, and accounting and audit companies in addition to direct and allotted facility-related prices. We anticipate that our normal and administrative bills will enhance within the future as we enhance our headcount to assist our continued analysis actions and improvement of our packages and platform. We additionally anticipate that we are going to proceed to incur elevated accounting, audit, authorized, regulatory, compliance, director and officer insurance prices and investor and public relations bills related to working as a public firm. Different Revenue (Expense) Curiosity Revenue Curiosity revenue consists of curiosity earned on our invested money balances. Different Revenue (Expense), Internet Different revenue (expense) ,internet consists of sublease revenue and miscellaneous expense unrelated to our core operations. Revenue Taxes As of December 31, 2022, we had federal and state internet working loss carryforwards of $221.7 million and $203.3 million, respectively, which can be obtainable to offset future taxable revenue. The federal internet working loss carryforwards embody $5.3 million which expire in 2037 and $216.4 million which carryforward indefinitely however in some circumstances could also be restricted to offset 80% of annual taxable revenue. The state internet working loss carryforwards expire at numerous dates starting in 2036. As of December 31, 2022, we additionally had federal

and state analysis and improvement tax credit score carryforwards of $9.6 million and $5.7 million, respectively, which can be obtainable to cut back future tax liabilities and expire at numerous dates starting in 2036 and 2031, respectively. On account of our historical past of cumulative internet losses since inception and uncertainties surrounding our means to generate future taxable revenue, we now have recorded a full valuation allowance towards our internet deferred tax belongings at every steadiness sheet date. We anticipate to have taxable revenue within the present 12 months, which will likely be lowered by using obtainable internet working loss carryforwards and analysis and improvement tax credit score carryforwards. 16 -------------------------------------------------------------------------------- Desk of Contents Important Accounting Estimates Our condensed consolidated monetary statements are ready in accordance with usually accepted accounting rules in the US ("GAAP"). The preparation of our condensed consolidated monetary statements and associated disclosures requires us to make estimates and judgments that have an effect on the reported quantities of belongings, liabilities, income, prices and bills and the disclosure of contingent belongings and liabilities in our condensed consolidated monetary statements. We base our estimates on historic expertise, identified tendencies and occasions and numerous different components that we imagine are cheap underneath the circumstances, the outcomes of which type the idea for making judgments about the carrying values of belongings and liabilities that aren't readily obvious from different sources. We consider our estimates and assumptions on an ongoing foundation. Our precise outcomes might differ from these estimates underneath totally different assumptions or circumstances. Whereas our vital accounting insurance policies are described in additional element in Be aware 2 to our consolidated monetary statements in our Annual Report on Type 10-Ok for the fiscal 12 months ended December 31, 2022 in addition to elsewhere on this Quarterly Report on Type 10-Q, we imagine that income recognition and accrued analysis and improvement bills are these most important to the judgments and estimates used within the preparation of our condensed consolidated monetary statements. There have been no materials adjustments to our crucial accounting insurance policies and estimates detailed within the Important Accounting Insurance policies and Important Judgements part of Merchandise 7. Managements Dialogue and Evaluation of monetary Situation and Outcomes of Operations in our Annual Report on Type 10-Ok for the fiscal 12 months ended December 31, 2022. Outcomes of Operations Comparability of the Three Months Ended March 31, 2023 and 2022 The next desk summarizes our outcomes of operations for 3 months ended March 31, 2023 and 2022: Three Months Ended March 31, 2023 2022 Change (in 1000's) Collaboration income $ 5,309 $ 3,920 $ 1,389 Working bills: Analysis and improvement 29,985 24,508 5,477 Basic and administrative 8,641 7,216 1,425 Complete working bills 38,626 31,724 6,902 Loss from operations (33,317) (27,804) (5,513) Different revenue (expense): Curiosity revenue 2,669 235 2,434 Different revenue, internet 720 655 65

Complete different revenue, internet 3,389 890 2,499 Loss earlier than revenue taxes (29,928) (26,914) (3,014) Provision for revenue taxes (560) - (560) Internet loss $ (30,488) $ (26,914) $ (3,574) Collaboration Income Collaboration income was $5.3 million for the three months ended March 31, 2023, in comparison with $3.9 million for the three months ended March 31, 2022. The enhance in collaboration income is attributed to the next: •a rise in Lilly collaboration income recognition of $0.9 million primarily attributable to work carried out on the BRM Selective program pursuant to the Lilly Collaboration Settlement; and •a rise in Merck collaboration income recognition of $0.5 million attributable to continued development of the only specified transcription issue goal underneath the Merck collaboration settlement. 17 -------------------------------------------------------------------------------- Desk of Contents Analysis and Improvement Bills The next desk summarizes our analysis and improvement bills for the three months ended March 31, 2023 and 2022: Three Months Ended March 31, 2023 2022 Change (in 1000's) Analysis and improvement program bills: FHD-286 $ 4,031 $ 4,475 $ (444) FHD-609 2,686 2,319 367 Platform, analysis and discovery, and unallocated bills: Platform and different early stage analysis exterior prices 7,104 5,164 1,940 Personnel associated (together with stock-based compensation) 10,373 7,911 2,462 Facility associated and different 5,791 4,639 1,152 Complete analysis and improvement bills $ 29,985 $ 24,508 $ 5,477 Analysis and improvement bills had been $30.0 million for the three months ended March 31, 2023, in comparison with $24.5 million for the three months ended March 31, 2022. The rise is attributed to the next: •a rise in personnel-related prices of $2.5 million, together with a $0.5 million enhance in stock-based compensation expense, due primarily to elevated headcount in our analysis and improvement operate; •a rise in platform and different early stage analysis investments of $1.9 million; •a rise in facility-related and different bills of $1.2 million, attributable to elevated investments to assist the rising analysis and improvement group and analysis efforts; •a rise in our FHD-609 program prices of $0.4 million related to the Part 1 medical trial in Synovial Sarcoma and SMARCB1-loss tumors. •This was barely offset by a lower in our FHD-286 program prices of $0.4 million primarily pushed by a decline in medical path spend as a result of FDA's full medical maintain on the Part 1 examine in AML/MDS in August 2022. Basic and Administrative Bills The next desk summarizes our normal and administrative bills for the three months ended March 31, 2023 and 2022: Three Months Ended March 31, 2023 2022 Change

(in 1000's) Personnel associated (together with stock-based compensation) $ 5,769 $ 4,070 $ 1,699 Skilled and consulting 1,624 1,712 (88) Facility associated and different 1,248 1,434 (186) Complete normal and administrative bills $ 8,641 $ 7,216 $ 1,425 Basic and administrative bills had been $8.6 million for the three months ended March 31, 2023, in comparison with $7.2 million for the three months ended March 31, 2022. The rise is primarily attributed to the next: •a rise in personnel-related prices of $1.7 million, together with a $0.8 million enhance in stock-based compensation expense, which was the results of elevated headcount in our normal and administrative operate to assist our rising enterprise. Different Revenue (Expense) Curiosity revenue was $2.7 million for the three months ended March 31, 2023, in comparison with $0.2 million for the three months ended March 31, 2022. The rise in curiosity and different revenue (expense), internet for the three months ended March 31, 2023 was attributable to a rise within the common rate of interest in comparison with three months ended March 31, 2022. Different revenue, internet was $0.7 million for the three months ended March 31, 2023 and 2022. 18 -------------------------------------------------------------------------------- Desk of Contents Provision for revenue taxes We recorded an revenue tax provision of $0.6 million for the three months ended March 31, 2023. The revenue tax provision is primarily pushed by the present federal and state taxes associated to the $300.0 million upfront fee for Lilly Collaboration Settlement, which will likely be acknowledged as taxable revenue within the present 12 months, and the required capitalization of analysis and improvement prices pursuant to Inside Income Code Part 174. The Firm didn't document a provision for revenue taxes for the three months ended March 31, 2022. Liquidity and Capital Assets Since our inception in October 2015, we now have incurred vital working losses. We anticipate to incur vital bills and working losses for the foreseeable future as we assist our continued analysis actions and improvement of our packages and platform. Via March 31, 2023, we now have funded our operations with proceeds from our IPO in October 2020, gross sales of most well-liked inventory, time period loans, an upfront fee of $15.0 million we obtained in July 2020 underneath the Merck Collaboration Settlement and proceeds we obtained in December 2021 underneath the Lilly SPA of $80.0 million; an upfront fee of $300.0 million obtained in January 2022 underneath the Lilly Collaboration Settlement and a fee of $5.0 million obtained from Merck underneath the Merck Collaboration Settlement for the achievement of a analysis milestone. As of March 31, 2023, we had money, money equivalents and marketable securities of $316.0 million. Money Flows The next desk summarizes our sources and makes use of of money for every of the intervals introduced: Three Months Ended March 31, 2023 2022 (in 1000's) Internet money supplied by (utilized in) working actions $ (31,180) $ 271,534 Internet money supplied by (utilized in) investing actions 29,505 (159,409) Internet money supplied by financing actions 102 384 Internet lower in money, money equivalents and restricted money $ (1,573) $ 112,509

Working Actions In the course of the three months ended March 31, 2023, working actions used $31.2 million of money, ensuing from the online money used to fund our internet lack of $30.5 million and adjustments in our working belongings and liabilities of $6.6 million partially offset by internet non-cash fees of $5.9 million. Internet money supplied by adjustments in our working belongings and liabilities for the three months ended March 31, 2023 was primarily pushed by a $5.3 million lower in deferred income ensuing from the popularity of income on the upfront funds obtained in reference to our collaboration agreements and a $1.7 million lower in working lease liabilities. In the course of the three months ended March 31, 2022, working actions supplied $271.5 million of money, ensuing from our adjustments in our working belongings and liabilities of $293.2 million and internet non-cash fees of $5.2 million partially offset by a internet lack of $26.9 million. Internet money supplied by adjustments in our working belongings and liabilities for the three months ended March 31, 2022 consisted primarily of the $300.0 million of money obtained associated to our collaboration receivable, a rise of $1.3 million in accounts payable and a lower of $0.2 million of pay as you go bills and different present belongings partially offset by a $3.9 million lower in deferred income ensuing from the recognition of income on the upfront funds obtained in connection with our collaboration agreements, a $2.5 million lower in accrued bills and different liabilities and a $1.8 million lower in working lease liabilities. Investing Actions In the course of the three months ended March 31, 2023 internet money utilized in investing actions was $29.5 million attributable to $26.2 million of purchases of marketable securities and $0.6 million in purchases of property and gear partially offset by $56.4 million of maturities of marketable securities. In the course of the three months ended March 31, 2022 internet money supplied by investing actions was $159.4 million attributable to $212.3 million of purchases of marketable securities and $0.2 million in purchases of property and gear partially offset by $53.1 million of maturities of marketable securities. 19 -------------------------------------------------------------------------------- Desk of Contents Financing Actions In the course of the three months ended March 31, 2023, internet money supplied by financing actions was $0.1 million consisting of internet proceeds from the train of frequent inventory choices and the worker inventory buy plan. In the course of the three months ended March 31, 2022, internet money supplied by financing actions was $0.4 million consisting of internet proceeds from the train of frequent inventory choices. Funding Necessities We anticipate our bills to extend considerably in reference to our ongoing actions, notably as we advance the preclinical actions, provoke medical trials for our product candidates in improvement and proceed to fund on-going medical efforts. As of the issuance date of those interim condensed consolidated monetary statements, we anticipate that our money, money equivalents and marketable securities will likely be ample to fund our working bills and capital expenditure necessities for a minimum of twelve months. We have now primarily based these estimates as to how lengthy we anticipate we will fund our operations on assumptions that will show to be inaccurate. We may use our obtainable capital sources earlier than we at the moment anticipate, during which case we might be required to acquire further financing earlier than deliberate, which is probably not obtainable to us on acceptable phrases, or in any respect. Our failure to boost capital as and when wanted would have a detrimental impression on our monetary situation and our means to pursue our enterprise technique. We will likely be required to acquire additional funding

by means of public or personal fairness choices, debt financings, collaborations and licensing preparations or different sources. If we're unable to boost ample capital as and when wanted, we could also be required to considerably curtail, delay or discontinue a number of of our analysis or improvement packages or the commercialization of any product candidate we might develop, or be unable to develop our operations or in any other case capitalize on our business opportunities. If we elevate further funds by means of collaborations or licensing preparations with third events, we might must relinquish invaluable rights to future income streams or product candidates or grant licenses on phrases that is probably not favorable to us. See "Danger Components" in our Annual Report on Type 10-Ok for the fiscal 12 months ended December 31, 2022 for extra dangers related to our substantial capital necessities. Off-balance Sheet Preparations We didn't have in the course of the intervals introduced, and we don't at the moment have, any off-balance sheet preparations, as outlined within the guidelines and laws of the Securities and Change Fee. Lately Issued Accounting Pronouncements An outline of just lately issued accounting pronouncements that will probably impression our monetary place and outcomes of operations is disclosed in Be aware 2 to our condensed consolidated monetary statements showing elsewhere on this Quarterly Report. © Edgar On-line, supply Glimpses https://guesthype.co.uk/?p=6312&feed_id=14345&cld=6458f008914fc

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anchromhptlc121 · 3 years ago

Text

HPTLC Fingerprinting

High Performance Thin Layer chromatography is a versatile technique with applications in herbals, food, pharmaceuticals, nutraceuticals.

What is HPTLC Fingerprinting?

HPTLC Fingerprinting is the representation of the phytochemical composition of a plant extract or formulation, in the form of an image at 254nm, 366nm and white light. It is a sequence of peaks or zones of a chromatogram specific for a sample.

United States Pharmacopoeia definition of HPTLC Fingerprint is “It is the electronic image of the visual HPTLC chromatogram.” HPTLC fingerprint is evaluated based on Rf, colour and relative intensity of bands in the electronic image.

For comparison BRM (Botanical Reference Material) is used. If BRM is not available a sample can be collected from the field/market sample is sent to recognized botanical institute e.g., NBRI Lucknow, Agharkar Research Institute Pune, Botanical survey of India western circle Pune. etc. for authentication and that can be used as BRM.

Phytochemical reference standards (RS) are also applied along with samples. Respective plant samples/ raw materials collected from different geographical locations/ climatic conditions can be applied to check the variation in species.

While developing HPTLC fingerprint for certain plant material aim should be to develop fingerprint which shows maximum no. of phytoconstituents with good resolution.

HPTLC for Herbal Chromatographic Fingerprinting

HPTLC technique can be used for herbal fingerprinting. Each plant has a different fingerprint pattern. When the plant extract is run in a suitable mobile phase the separation pattern observed is the herbal fingerprint of the said plant. HPTLC is a preliminary step to identify phytochemical compounds and secondary metabolites of a plant.

Fingerprints play an important role in quality control of herbal medicine. It can be used for authentication of raw material or detection of confounded material/ substitutes.

Herbal products and drugs are gaining momentum and so is the substandard material being added to gain profits by manufacturers. Consumers are growing towards organic products. HPTLC plays a major role in detection of such adulterated material.

Herbal Fingerprinting is the technique used for the qualitative and quantitative analysis of herbal components in drugs. Chromatographic fingerprinting is used for both establishing the identity and quality of the herbs being added into formulation.

With a sample size of more than 100 samples in parallel, using Chromatographic Fingerprinting is not only fast and effective, but also economically flexible. Modern chromatographic fingerprinting is used at dual stages during the manufacture of an herbal formula. An initial fingerprinting is carried out for each of the herbs being added to the formulation.

Once the identity and purity of the herb is established all the herbs are incorporated in suitably processed to produce the final poly herbal formulation. A chromatographic fingerprint of the poly herbal formulation is developed after the development of the poly herbal formulation.

An HPTLC analysis is useful to measure the purity, strength and consistency of the chemical profile. HPTLC adoption as compared to Gas Chromatography and High-Performance Liquid Chromatography, produces faster results in the standardisation of a consistent biological activity.

If you want to perform HPTLC and Herbal fingerprinting for your business, we provide CAMAG HPTLC machines at an affordable price. Contact us for a quote today.

#chromatographic fingerprinting #CAMAG HPTLC #Herbal fingerprinting

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lvjunkout702 · 3 years ago

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brmchemical · 6 months ago

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Herbal Extracts for Beginners: What You Need to Know

Introduction to Herbal Extracts

In our ongoing quest for optimal health and wellness, nature often holds the keys to the most effective solutions. Herbal extracts represent a potent form of botanicals that have been harnessed for centuries to promote health and ward off disease. At BRM Chemicals, we delve deep into the intrinsic properties of plants to offer you a diverse range of extracts through our meticulously curated Herbal Extracts Collection.

What Are Herbal Extracts?

Herbal extracts are dynamic, concentrated preparations derived from the best quality herbs. These extracts isolate and enhance the active compounds found in the plant material, believed to be responsible for the plant's therapeutic effects. The result is a highly potent formulation that delivers targeted benefits, which can be utilized in everything from dietary supplements to beauty and skincare products.

READ MORE BLOG :-

Benefits of Herbal Extracts

The benefits of using herbal extracts are profound and varied. They can help improve immune function, reduce inflammation, support heart health, and enhance mental clarity. Specific extracts like Ginseng are known for their energy-boosting properties, Echinacea for its immune-supportive effects, and Green Tea for its antioxidant capabilities. Each extract in our collection at BRM Chemicals offers unique health-promoting qualities designed to support and enhance various aspects of your health.

How Herbal Extracts Are Made

The journey to creating powerful herbal extracts involves several critical steps. It begins with the careful selection of the highest quality herbs, followed by their harvesting at peak potency. At BRM Chemicals, we employ advanced and respectful extraction methods such as cold pressing and solvent extraction, which ensure that the full spectrum of the plant's beneficial compounds is preserved, maximizing the therapeutic potential of each extract.

Using Herbal Extracts in Daily Life

Integrating herbal extracts into your daily routine can significantly impact your overall health and well-being. They can be seamlessly added to your diet through teas, incorporated as a supplement regime, or used in personal care products for topical application. Aloe Vera extract, for instance, is a fantastic option for enhancing skin hydration and soothing irritation, while Turmeric extract is excellent for its anti-inflammatory and antioxidant properties.

Why Choose BRM Chemicals for Your Herbal Extracts?

At BRM Chemicals, our dedication to quality is paramount. We source only the finest herbs, utilize advanced extraction techniques, and conduct rigorous quality control checks to ensure that every product we offer is of the highest standard. Our commitment extends beyond quality; we strive to provide our customers with the knowledge and support needed to make informed health choices.

Conclusion: Enhance Your Wellness with Herbal Extracts

Incorporating herbal extracts into your wellness routine is an accessible and effective way to leverage the natural power of plants for your health. With an extensive range of options to choose from, BRM Chemicals provides you with tailored solutions to meet your health needs.

Discover the potency of nature condensed into our premium extracts. Shop Now and begin your journey to a more natural and vibrant health with BRM Chemicals!

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towingserlas541 · 4 years ago

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Fast Dead Battery Help Service in Las Vegas NV | Towing Services of Las Vegas

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No one plans on having their battery up and quit on them. This is why jumper cables seem to be a rare commodity when you do have issues. Your battery was probably working fine- until it wasn’t. The hot NV summers can cause battery fluid evaporation which leads to a dead battery by the time winter arrives. Colder weather can slow down the chemical reaction required to start your car and prevent your battery from working up the required juice. This is why a lot of older batteries just plain work better in warmer weather and also why we find ourselves with a lot of dead batteries when the weather gets cold!

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10 Cities within 30 miles of Las Vegas, NV

the zip codes in Clark County, NV and the city/neighborhood in which the zip code is in: 89002 (Henderson), 89005 (Boulder City), 89011 (Henderson), 89012 (Henderson), 89014 (Henderson), 89015 (Henderson), 89016 (Henderson), 89030 (North Las Vegas), 89031 (North Las Vegas), 89032 (North Las Vegas), 89044 (Henderson), 89052 (Boulder City), 89074 (Henderson), 89081 (North Las Vegas), 89084 (North Las Vegas), 89085 (North Las Vegas), 89086 (North Las Vegas), 89087 (North Las Vegas), 89101 (Las Vegas), 89102 (Las Vegas), 89103 (Las Vegas), 89104 (Las Vegas), 89106 (Las Vegas), 89107 (Las Vegas), 89108 (Las Vegas), 89109 (Las Vegas), 89110 (Las Vegas), 89113 (Las Vegas), 89115 (Las Vegas), 89117 (Las Vegas), 89118 (Las Vegas), 89119 (Las Vegas), 89120 (Las Vegas), 89121 (Las Vegas), 89122 (Las Vegas), 89123 (Las Vegas), 89124 (Las Vegas), 89128 (Las Vegas), 89129 (Las Vegas), 89130 (Las Vegas), 89131 (Las Vegas), 89134 (Las Vegas), 89135 (Las Vegas), 89138 (Las Vegas), 89139 (Las Vegas), 89141 (Las Vegas), 89142 (Las Vegas), 89143 (Las Vegas), 89144 (Las Vegas), 89145 (Las Vegas), 89146 (Las Vegas), 89147 (Las Vegas), 89148 (Las Vegas), 89149 (Las Vegas), 89156 (Las Vegas), 89158 (Las Vegas), 89161 (Las Vegas), 89166 (Las Vegas), 89169 (Las Vegas), 89178 (Las Vegas), 89179 (Las Vegas), 89183 (Las Vegas).

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pureyarn · 4 years ago

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BRM designers and engineers apply a multi dimensional

Bally Ribbon Mills (BRM), designer and producer of highly engineered woven fabrics, recently presented a specialized line for aerospace and aviation and aerospace. The fabrics satisfy detailed strength requirements for structural components. It’s woven webbing is already used at the International Space station and at NASA’s Mars Exploration Rover Opportunity, as well as in parachutes, cargo restraint systems, flight suits, flotation devices, air slides, seatbelts, and other safety systems.

BRM’s current groundbreaking fabrics contain a patented 2-D and 3-D Thermoplastic Composite Materials and recently engineered E-Webbings. The Thermoplastic Composite Materials provide pinpointed reinforcement, specific superior strength, increased flexure, impact resistance, and resistance in varied molding/forming processes.

BRM designed the product line for the Internet of Things technology zone, which is intended for the individual, commercial, and military aircraft area. E-Webbings delivers conductive and structural components that integrate sensors and other equipment.

BRM designers and engineers apply a multi-dimensional, continuous weaving method to create lightweight, cost-effective, advanced woven 2-D and 3-D thermoset and thermoplastic polymer composite structures. Its products focus on durability and resist chemicals, abrasion, weather, and heat. As well as increasing safety, its lightweight webbing costs less Chinese Handtufted Carpet Yarn than aluminum and steel and its unique production method can be customized to meet end user requirements.

Ecomass Technologies

Since 1998, Ecomass Technologies has produced innovative solutions through thermoplastic composite materials, high density polymers, and high density plastics. It specializes in high density and lead replacement applications, which can be utilized in a wide array of applications, including vibration dampening, radiation shielding, gamma ray shielding, and x-ray shielding.

Ecomass works with both government and commercial clients to solve issues, develop solutions, and meet application needs. Its never-ending training, skills, and experience in the formulation and development of high density thermoplastic compounds offers its customers the freedom to design and focus on form and function, while it solves the challenges their products face. Its goal is to enable its customers to design and produce the best parts possible by providing them with the highest-performance and lowest-cost materials so that they can succeed and prosper in their markets.

Ecomass’ high gravity compounds are designed to replace traditional high density materials such as lead and other metallic materials. Its high gravity compounds can be formulated up to the density of lead and deliver the weight and physical properties of metal with the design and production advantages of injection molded plastics. They can be injected or compression molded. Such eliminates the need for secondary operations and reduces costs.

Ecomass Compounds satisfy the international regulatory concerns of the international marketplace, are completely nontoxic, and meet the EU RoHS Directives

Ecomass’ customer service team is recognized for its skill and responsiveness. See its website for contact information and its RFQ Form. It’s probably already worked on the solution you’re seeking.

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network-blr · 4 years ago

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Global Application Delivery Network Market-Industry Analysis and forecast 2019 – 2027: By Deployment Type, End-user and Region.

Global Application Delivery Network Market size was valued US$ XX Bn. in 2019 and the total revenue is expected to grow at XX% through 2019 to 2027, reaching nearly US$ 13.2 Bn.

The report study has analyzed revenue impact of COVID -19 pandemic on the sales revenue of market leaders, market followers and market disrupters in the report and same is reflected in our analysis.

Market Definition:

An Application Delivery Network or (ADN) is a group of services deployed simultaneously over a network to offer application security, availability, visibility and acceleration from application servers to the end-user application.

Market Dynamic:

The scope of the report includes a detailed study of global and regional markets for application delivery network market with the reasons given for variations in the growth of the industry in certain regions. The technology prevailing in the ADN market is highly demanded to satisfy the need for improved application security and mobility in a disorganized firm. On a real-time basis, the application delivery network technology can help to classify and prioritize applications as well as the user’s access and content. All the real-time based applications, both internal and external in an organization can be accelerated with the help of ADNs. Also, ADN technology helps in keeping a check on the growing expenses of network management. It can be very inventive for delivering fast and secure applications through an organization and also protect against malicious content or applications.

The challenges in the cloud data centers contain insecurity in public, private, and hybrid clouds. This upsurges the requirement for security in cloud-based data centers and raises the need for security provided that ADNs an opportunity to manage the security, addressing visibility, and performance needs of the businesses.

Market Trends:

The report covers all the trends and technologies playing a major role in the growth of the application delivery network market over 2019-2027. The on-going trend gaining momentum in the market is the high adoption of SaaS applications by enterprises. The adoption of SaaS across the world for a wide variety of application areas demands business agility. SaaS applications offer strong adoption and steady growth. The use of SaaS is around 25% in Germany and 30% in the U.K. Now, the use of SaaS in IT enterprises is approximately 60%, with Google Apps comprising 30%, Microsoft Office 38% and Dropbox 23%.

Market Segmentation:

Cloud segment was valued at US$ XX.24 Mn in 2019 and is expected to reach at US$ XX.43Mn by 2027 at a CAGR of XX.34% over the forecast period. Cloud platforms are enhancing managing more globally-based integration networks and complex business models. Apart from providing the same capabilities as an on-premises system, cloud platforms are very flexible for always-changing business needs. Likewise, the report will provide an accurate prediction of the contribution of the products segments to the growth of the ADN market size.

Regional Analysis:

North America ADN market was valued at US$ XX.12 million in 2019 and is expected to reach a value of US$ XX.23 million by 2027, with a CAGR of XX.76% during the forecast period. Europe is the second-largest ADN market following North America. North America largely occupies all the major companies plying in AND market and is also an advanced region in terms of quick adoption of developing technology usage, and analytic application in many industries like automotive, telecommunication, retail and therefore a lot of scope for of application delivery management.

Industry Updates:

The research study includes the profiles of leading companies operating in the global application delivery network market. Such as, In Nov 2019, Oracle Company Introduces Cloud-Native Modern Monetization-Digital service providers are transforming their monetization systems to prepare for the future demands of 5G and future digital services.

Oracle Communications’ novel cloud-native deployment option for Billing and Revenue Management (BRM) addresses these demands by merging the features and extensibility of a proven, convergent charging system with the DevOps agility and efficiency of the cloud.

The objective of the report is to present a comprehensive analysis of the Global Application Delivery Network Market including all the stakeholders of the industry. The past and current status of the industry with forecasted market size and trends are presented in the report with the analysis of complicated data in simple language. The report covers all the aspects of the industry with a dedicated study of key players that includes market leaders, followers and new entrants. PORTER, SVOR, PESTEL analysis with the potential impact of micro-economic factors of the market has been presented in the report. External as well as internal factors that are supposed to affect the business positively or negatively have been analyzed, which will give a clear futuristic view of the industry to the decision-makers.

The report also helps in understanding Global Application Delivery Network Market dynamics, structure by analyzing the market segments and projects the Global Application Delivery Network Market size. Clear representation of competitive analysis of key players by Application, price, financial position, Product portfolio, growth strategies, and regional presence in the Global Application Delivery Network Market make the report investor’s guide. Scope of the Global Application Delivery Network Market

Global Application Delivery Network Market, By Deployment Type

• Cloud-based • On-premises Global Application Delivery Network Market, By End-user

• BFSI • IT and Telecommunications • Healthcare • Government • Manufacturing • Others Global Application Delivery Network Market, By Region

• Asia Pacific • North America • Europe • Latin America • Middle East Africa Key players operating in the Global Application Delivery Network Market

• ARYAKA NETWORKS, INC. • Array Networks, Inc. • Brocade Communications Systems, Inc. • Dell • SANGFOR TECHNOLOGIES INC. • Networx Australia • Procera Networks. • Hewlett Packard Enterprise • SynerComm, Inc • A10 Networks, Inc • Symantec Corporation, etc. • Cisco Systems Inc. • Citrix Systems Inc. • F5 Networks Inc. • Oracle Corporation

About Us:

Maximize Market Research provides B2B and B2C market research on 20,000 high growth emerging technologies & opportunities in Chemical, Healthcare, Pharmaceuticals, Electronics & Communications, Internet of Things, Food and Beverages, Aerospace and Defense and other manufacturing sectors.

Contact info: Name: Vikas Godage Organization: Maximize Market Research Pvt.Ltd.Pune Email: [email protected] Contact: +919607065656 / +919607195908 Website:www.maximizemarketresearch.com

#Global Application Delivery Network Market

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handymanservicesvegas · 4 years ago

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Reliable Deck Contractor Deck Repair Service Deck Installation in Las Vegas NV | Vegas Handyman Services

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Las Vegas NV Deck Contractor: Vegas Handyman Services provide a wide array of decking options from the standard treated wood decks to the latest innovations in composite and pvc decking, as well as decorative railing. We offer professional services delivering quality craftsmanship that is guaranteed to satisfy your project needs. All projects come with a 2 year labor warranty and corresponding material manufacturer’s warranty.

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DECK CONTRACTOR

Having a homemade, custom deck on your property can completely transform your outdoor space and provide an excellent venue for hosting friends and family. For over 10 years, Decks has been handcrafting gorgeous custom decks for all of our customers in the Atlanta area. Decks are the premier source for outdoor decks. Our staff and craftsmen are experts in deck construction and design and we are knowledgeable and ready to help you start the process of building your deck. Whether you’ve never had a deck on your property or want to add another, Decks has you covered.

DECK CONSTRUCTION

Here at Decks, we are experts in several different types of deck materials. As experienced deck builders, we have the expertise in which woods work better depending on your property. The right wood can add a distinctive feel to a property that the wrong wood and style cannot. The experts at Decks can help you pick out the right wood that will be perfectly suited for your property. Our customers have come to rely on our team’s deck construction specialists to provide all of the information needed to start on your deck building project. There is a variety of deck types available and they include:

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DECK BUILDERS

Our deck builders and designers here at Decks take immense pride in our work, both in craftsmanship and customer service. We want our customers to be proud of the new addition to their property and a happy customer will help spread the word. High quality, customized decks are our specialty. We take our rating seriously and always want to be known as a customer driven business. You help us thrive and continue to help build beautiful decks, and we thank you for your support .Best of all, FREE consultations are available with our deck experts if you are beginning the process of building or simply want more information on the different types of decks. Our rates are competitive and we want you to be 100% satisfied every step of the way. Adding a deck to any property can completely transform the space and add a lot to your quality of life. If you are planning on renting or selling your property, a high quality deck is an excellent investment that can greatly impact the value of your home or property. For the best deck builders throughout Las Vegas NV, call Vegas Handyman Services today.

We specialize in designing and building new decks as well as repairing existing decks. In order to minimize any future problems with a deck, we use composite decking. This ensures your deck not only will last, but will remain beautiful. But you have options, and if you would rather not use composite decking, we can also build your deck using a pressure treated wood.

By designing an under-deck framing system with the outdoors in mind, we've reinvented the concept, creating a remarkably stable and consistently flat, triple-coated steel substructure on which to build a high-performance deck something other deck frames could only dream about.

We make Decking eco-friendly composite decks from an innovative blend of 95% recycled wood and plastic film that’s almost the whole thing. On top of that, our company uses some of the most earth-friendly manufacturing processes in the country, reclaiming factory waste and eliminating the use of harmful chemicals. The fact is, being green is in our DNA. We've been this way for more than 20 years, well before green was a buzzword. Because in the end, all of us want to look out on our decks and know that we’ve done our part.

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maximizenetwork · 4 years ago

Text

Global Application Delivery Network Market-Industry Analysis and forecast 2019 – 2027

Global Application Delivery Network Market size was valued US$ XX Bn. in 2019 and the total revenue is expected to grow at XX% through 2019 to 2027, reaching nearly US$ 13.2 Bn.

The report study has analyzed revenue impact of COVID -19 pandemic on the sales revenue of market leaders, market followers and market disrupters in the report and same is reflected in our analysis.

Market Definition:

Market Dynamic:

Market Trends:

Market Segmentation:

Regional Analysis:

Industry Updates:

Global Application Delivery Network Market, By Deployment Type

• Cloud-based • On-premises Global Application Delivery Network Market, By End-user

• BFSI • IT and Telecommunications • Healthcare • Government • Manufacturing • Others Global Application Delivery Network Market, By Region

• Asia Pacific • North America • Europe • Latin America • Middle East Africa Key players operating in the Global Application Delivery Network Market

About Us: Maximize Market Research provides B2B and B2C market research on 20,000 high growth emerging technologies & opportunities in Chemical, Healthcare, Pharmaceuticals, Electronics & Communications, Internet of Things, Food and Beverages, Aerospace and Defense and other manufacturing sectors.

Contact info: Name: Vikas Godage Organization: MAXIMIZE MARKET RESEARCH PVT. LTD. Email: [email protected] Website:www.maximizemarketresearch.com

#Application Delivery Network Market Analysis

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delicatelyvaliantchaos · 6 years ago

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bradleybowles-blog · 7 years ago

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25 Main reasons Norway Is The Greatest Place On Planet.

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I believe some of the largest points our company can possibly do on Olive Backyard to Go is actually strengthen our functions as business has actually improved, Dave and also Dan and also the staff continuously deal with creating far better devices to manage the quantity. What specifies the DR aside from various other Caribbean countries and islands is its own a lot more advanced way of living - one that is firmly International. The desirable function of the stock is actually the possibility to own allotments of a very tiny yet fast-growing provider and the possibility to take part in an extended period from durable growth as well as portion increases resulting in investment profits equaling multiples of the original financial investment value, need to traits cultivate as hoped. Details regarding several of these threat and unpredictabilities could be located in our earnings news release provided this morning, and along with our Form 10-Q for the one-fourth finished September 30, 2017. Yeah, terrific concern, Scott, around our SD-WAN and UCaaS solutions, which right now, as our experts referred to today together with our on-net sales, are actually adding 36% of our sales in the third quarter. Apologies for advising that you have not currently done this and also are actually method before me: I expect for me (with a history of modelling natural information relative to chemical design) the main concern is that that the style must be actually refined constantly, making use of instruction collections as well as examination collections, till that makes sense whichever technique you examine it. Therefore remove some of the motorists when you develop the design and observe where they at that point can be found in. Get rid of a different batch and observe if everything still compares. The main issue is actually that the information must match along with just what we know - yet clearly there is no other way software-tools-Bot.Info to know" whether Senna was better compared to Fangio, yet couple of would certainly doubt that he was much better compared to Rosberg. Assimilation associated activity is actually peaking as our experts shift distribution systems featuring our primary line supplier, create distributors and also smallware vendors, transform point of sales bodies in 10 dining establishments per week which likewise consists of 2 weeks from instruction for dining establishment prior to transformation, completely transition Cheddar's payroll device on the Darden payroll system and also finally, our company just completed open registration and also Cheddar's staff member are going to be switch to Darden benefits at the beginning of the fiscal year. Lastly, regarding USA clay performance: our company believe the development as well as growth this industry is undoubtedly tough, yet our work suggests that the market might potentially be a little overstating U.S. creation growth in 2018. He outperformed his ally 32-19 in training, 19-7 in competitions, as well as 160-116 in aspects. He began the full week with 78 EV in the Weak Trump pillar, however ended this with simply 29 EV. Both Indiana and also Texas moved to Barely Trump, which raised the Hardly Trump classification from 21 EV to 70 EV for the full week. Generate a Compact Disc or playlist full of your loved one's preferred songs. With new control accountable as well as limitations that were introduced by Johnson Controls raised, Adient could possibly right now create the essential changes to reignite profits development, increase capital creation and also switch frames higher.

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amanda2020jumi-blog · 4 years ago

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Foshan hanluoya Furniture Co., Ltd.

Foshan hanluoya Furniture Co., Ltd. provides furniture suppliers of Hohhot Hotel, coffee shop, hotel suite and western restaurant. Foshan hanluoya home furnishings Co., Ltd. produces and sells dining table and chair furniture for hotels, mobile phones 176-2066-5005 (wechat), QQ: 285227171. Provide customized catering furniture, customized sales table and chair furniture can meet the individual needs of different restaurant styles such as western restaurant / coffee shop / hotpot shop / theme restaurant / hotel standard room suite / industrial style / dessert shop / milk tea shop / Tea Restaurant / KTV / foot bathing / bar. At the beginning of its business in 2013, hanloya made hotel and restaurant furniture, based on its rich experience and strength in furniture manufacturing, with its breakthrough in understanding the demand for restaurant furniture, with many years of export experience, supporting restaurant furniture for Sheraton Hotel, Greater China Hotel, shangri la hotel restaurant furniture, and 800 decoration and design companies across the country. Hanluoya has won the recognition and good reputation of our customers with its exquisite technology and high-quality service. The company adopts production equipment, has a number of skilled production team, and establishes a perfect computerized management system, winning the trust and support of customers.

Han Luo Ya furniture company, with the inspiration of traditional crafts, absorbing the essence of technology, giving full play to the wisdom of outstanding talents, meeting the needs of the clients, developing the purpose, manufacturing technology and perfect service system, firmly occupy the furniture market, is also making good quality and batch customization.Space for work.

after years of pursuit, hanloya furniture has developed a variety of styles of furniture, products --- all over the country and exported to the United States, Britain, Singapore, Japan, Italy, Germany, Thailand, South Korea, Canada, Australia, South Africa, Malaysia, France, etc. In recent years, based on the market development and the continuous expansion of domestic customer demand, our factory has timely seized the market opportunity, with theme style as the main line, independently researched and developed, and constantly innovated to produce more new products, which have become the product of various Western restaurants / coffee shops / hotpot shops / theme restaurants / standard suites of hotels / industrial styles / dessert shops / milk tea shops / tea restaurants / KTV / foot bathing / bars, etc. It has already provided table and chair furniture for catering enterprises, such as xiaotailang, huangjihuang, Quanjude, doulao, awashanzhai, DongLaiShun, happy lemon, Maojiawan, Starbucks, grandma's home, Huangji, Xibei youmian village, wangxiangyuan, hanashan, Shangdao coffee, cross-strait coffee, xuliushan, Manji dessert, weiqianla noodles, Daliang dumplings, etc. Han Luoya furniture can be based on Customers design drawings to customize the production of furniture, better reflect the overall design style and size of the cooperation.

the reason why the series products of "hanluoya hotel furniture" can be sold for a long time in today's furniture brands and fierce market competition depends on the quality, social support and the trust of consumers. We always adhere to the tenet of market-oriented, technology as the core and quality as the life. We don't talk about nothing but do practical things. Continuously develop new products. In the 21st century, human beings are making continuous progress,People's life and requirements are constantly improving. People of yundahong company will pursue infinite aesthetic feeling with persistent enthusiasm to surpass themselves and go to the world! Make unremitting efforts to create elegant living space for human beings!

when contacting us, please make sure that you see this information on the website of 100 merchants, thank you!

link to this article:

key words: coffee shop tables and chairs - coffee shop furniture - hotel tables and chairs - hotel furniture - hotpot shop tables and chairs

Shenzhen Weisheng machinery Co., Ltd. provides ge160fw-2rs German Durbar bearing ge40aw. Shenzhen Weisheng Machinery Co., Ltd. sells the German Durbar bearing ge40aw of the DGE 160 fw-2rs, and provides relevant consulting services for the German Durbar bearing ge40aw customers. If you need to know the model size, weight, price, installation, maintenance and other information of the German Durbar bearing ge40aw of the DGE 160 fw-2rs, please contact us.

EF 50-20-501 > bef05-20-502 German durbal bearing > ge40aw > German durbal joint bearing bef10so-61-501 > pm05-01-502 > German durbal joint bearing bef18-60-501 > befn25-90-501 > brtm3 / 4-00-501 > brf20-00-502 > dgeg-12-e > bef30-20-501 > dgeg 12 e

the German duel bearing, 160 uk-2rs, sold by Shenzhen Weisheng Machinery Co., Ltd. for the German duel bearing, 160 fw-2rs, for the German duel bearing, 160 fw-2rs Uk-2rs customers provide relevant consulting services. If you need to know the model size, weight, price, installation, maintenance and other information of German Durbar bearing, such as DGE 160 fw-2rs, please contact us.

DGE 160 fw-2rs German Durbar bearing DGE 160 uk-2rs_ Durbal bearing_ Durbal joint bearing_ Durbar end bearing_ Durbal rod end joint bearing_ Durbal bearing agent_ Durbal agent_ Durbal authorized agent

German durbal company has more than 70 years of experience as a bearing manufacturer. Its products move in a unique rolling way of ball or roller, so it is better than the ordinary ones that move in a sliding wayThe load and speed of the joint bearing are increased. Durbal has series models of BEF, BEM, BRF, BRM, brtf, BRTM, EF, EM, PF, PM, etc. the inner diameter of durbal has metric system and British system, and the bearing material has ordinary steel and stainless steel. Durbar high speed joint bearing is widely used in machinery, food and beverage machinery, packaging machinery, chemical machinery Durbar in Germany has series models such as bef, BEM, BRF, BRM, brtf, BRTM, EF, EM, PF, PM, etc. BRM: external thread, shielding adapter size according to DIN 648, K series BRM: external thread, protective cover size in inches BRF : internal thread, shield adapter size according to DIN 648, K series BRF inch: internal thread oil, low maintenance, shield size in inch PM: external thread PF: internal thread BRTM: external thread, shield adapter size according to DIN 648, For K series BRTM inch external thread, the size of protective cover is in inches brtf: internal thread, size of shielding adapter oil. According to DIN 648, K series brtf inch: internal thread, size of protective cover is in inches, K series German durbal company produces high-speed joint bearing. The product moves in its unique rolling way of ball or roller, so it is better than the common sliding wayThe load and speed of the joint bearing are increased. The inner diameter is metric and British, and the bearing material is ordinary steel and stainless steel. Durbal high speed joint bearing is widely used in machinery, food and beverage machinery, packaging machinery, chemical machinery. Al brtf16, durbal brtf20, durbal brtf25, durbal brtf30, durbal bef5, durbal bef6, durbal bef8, durbal bef10, durbal bef12, durbal bef14 ,durbal bef16 ,durbal bef18, durbal bef20, durbal bef22, durbal bef25, Durbal bef30

German durbal high speed rod end joint bearing is mainly used in packaging machinery, textile machinery, printing machinery, -- machinery, engineering machinery, agricultural machinery, ship machinery, lifting equipment, gas turbine, hydraulic equipment, industrial robot, rail transit and many other fields. 501 means right, 502 means left. BRTM series is external thread roller bearing, the specific models include: brtm12-00-501, brtm16-00-501, brtm20-00-501, brtm25-00-501, brtm30-00-501, brtm35-00-501, brtm40-00-501; brtm12-30-501, brtm16-30-501, brtm20-30-501, brtm25-30-501, brtm30-30-501, brtm35-30-501, brtm40-30-501; brtm1/2-00-501，brtm5/8-00-501，brtm3/4-00-501，brtm1/1-00-501，brtm1 /1-01-501 brtm12-00-502，brtm16-00-50- 502, brtm1 / 1-01-502 brtf series are internal thread roller bearings, Specific models include: brtf12-00-501, brtf12-01-501, brtf16-00-501, brtf16-01-501, brtf20-00-501, brtf25-00-501, brtf30-00-501, brtf35-00-501, brtf40-00-501; brtf12-30-501, brtf12-31-501, brtf16-30-501, brtf16-31-501, brtf20-30-501, brtf25-30-501, brtf30-30-501，brtf35-30-501，brtf40-30-501; brtf1/2-00-501，brtf5/8-00-501，brtf3/4-00-501，brtf1/1-00-501，brtf1 /1-00-501 brtf12-00-502，brtf12-01-502，brtf16-00-502，brtf16-01-502，brtf20-00-502，brtf25-00-502, brtf30-00-502，brtf35-00-502，brtf40-00-502; brtf12-30-502，brtf12-31-502，brtf16-30-502, Brtf16-31-502, brtf20-30-502, brtf25-30-502, brtf30-30-502, brtf35-30-502, brtf40-30-502; brtf1 / 2-00-502, brtf5 / 8-00-502, brtf3 / 4-00-502, brtf1 / 1-00-502, brtf1 / 1-00-502 BRM series are externally threaded double row ball joint bearings, specific models include: brm06-00-501, brm08-00-501, brm10-00-501，brm12-00-501，brm14-00-501，brm16-00-501，brm18-00-501，brm20-00-501，brm22-00-501，brm25-00-501，brm30-00-501; brm06-60-501，brm08-60-501，brm10-60-501，brm12-60-501，brm16-60-501，brm20-60-501; brm1/4-00-501，brm3/8-00-501，brm1/2-00-501，brm5/8-00-501，brm3 /4-00-501，brm1/1-00-501，brm1/1-01-501 brm06-00-502，brm08-00-502，brm10-00-502，brm12-00-502，brm14-00-502，brm16-00-502，brm18-00-502，brm20-00-502，brm22-00-502，brm25-00-502，brm30-00-502; brm06-60-502，brm08-60-502，brm10-60-502，brm12-60-502，brm16-60-502，brm20-60-502; Brm1 / 4-00-502, brm3 / 8-00-502, brm1 / 2-00-502, brm5 / 8-00-502, brm3 / 4-00-502, brm1 / 1-00-502, brm1 / 1-01-502

BRF series are internal thread double row ball joint bearings, with specific model package - 501, brf12-60-501, brf16-60-501, brf20-60-501; brf1/4-00-501，brf3/8-00-501，brf1/2-00-501，brf5/8-00-501，brf3 /4-00-501，brf1/1-00-501，brf1/1-01-501 brf06-00-502，brf08-00-502，brf10-00-502，brf10-01-502，brf12-00-502，brf12-01-502，brf14-00-502，brf16-00-502，brf16-01-502，brf18-00-502，brf20-00-502，brf22-00-502，brf25-00-502，brf30-00-502; brf06-60-502，brf08-60-502，brf10-60-502，brf12-60-502，brf16-60-502，brf20-60-502; 01-501, pm12-00-501，pm12-01-501，pm15-00-501，pm15-01-501，pm17-00-501，pm17-01-501，pm20-00-501，pm20-01-501 pm05-00-502，pm05-01-502，pm06-00-502，pm06-01-502，pm08-00-502，pm08-01-502，pm10-00-502，pm10-01-502，pm12-00-502，pm12-01-502，pm15-00-502，pm15-01-502，pm17-00-502，pm17-01-502，pm20-00-502，pm20-01-502 PF series is double row ball joint bearing with internal thread. The specific models include: pf10-00-501, pf15-00-501, pf20-00-501 pf10-00-502, pf15-00-502, pf20-00-502 WLT series is roller bearing. The specific models include: wlt12-00-500, wlt16-00-500, wlt20-00-500, wlt25-00-500, wlt30-00-500, wl35-00-500, wlt40-00-500; wlt12-30-5500 BEM 0-60-501, bem12-60-501, bem14-60-501.65292;well-16-60-501 to 65292;well-18-6060-501 to 65292;well-20-60-501.65-292;22-60-501, well-25-60-501, 65292292; well-30-60-60-50-50-501; well-0-0-5-0-0-0-5-501-90-501-65-65-65-656565656565229229;well-202020202029;well-6-6-90-90-90-90-90;well-90-90-90-90-0-0-0;well-0-0-0-0-0;well-0-0-6-0-0-0-0 1.65292;bem16-90-501,65292;bem18-90-501*65292;bem20-90-501*65292bem22-90-90-501, bem25-90-501 and 65292; bem30-90-501; 65292;bem3/8-20-501 to 65292;bem1/2-20-501.65292;well-1/2-20-501 to 65292.5/8-20-501.65292.65222.well-3/8-20-501/8-20-501.65-65-29222;well-1/1/1/1-21-21-501-501-501-501.--501-501.--501<br_>_eeeeeeeee20202020202020202020202020202020202020202020202020202020202020202020202020202020202020202020202020202020;bem12-20-502.65292;bem14-20-502,652922b;bem16-20-502,65292E-18-20-5020-502; bem05-60-502，bem06-60-502，bem08-60-502，bem10-60-502，bem12-60-502，bem14-60-502，bem16-60-502，bem18-60-502，bem20-60-502，bem22-60-502, bem25-60-502， bem30-60-502; bem05-90-502，bem06-90-502，bem08-90-502，bem10-90-502，bem12-90-502，bem14-90-502，bem16-90-502，bem18-90-502，bem20-90-502，bem22-90-502, Bem25-90-502, bem30-90-502; bem1 / 4-20-502, bem3 / 8-20-502, bem1 / 2-20-502, bem5 / 8-20-502, bem3 / 4-20-502, bem1 / 1-20-502, bem1 / 1-21-502 bef series are internal thread oil-free joint bearings, specific models include: bef05-20-501, bef05-21-501, bef06-20-501, bef08-20-501.f.10-20-501.f.10-21-501.f.12-20-501.f.12-21-501.f.14-20-501.f.16-20-501.f.16-21-501.f.18-20-501.f.20-501.f.22-20-501.f.25-20-501.f.30-20-501; 1919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919501'bef30-60-501'bef30-61-501; (b) the Commission's proposal for a Council Directive on the approximation of the laws, regulations and administrative provisions of the Member States;f14-90-501 -bef16-90-501 -bef16-91-501 -bef18-90-501 -bef20-90-501 -bef22-90-501 -bef25-90-501 -bef30-90-501 -bef30-91-501; bef1/4-20-501'bef3/8-20-501'bef1/2-20-501'bef5/8-20-501'bef3 /4-20-501'bef1/1-20-501'bef1/1-21-501 <<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<1919191919191919191919202020202020202020202020202020202020202020202020202020202020202020202020202020191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919191919192'bef30-21-502; bef05-60-502'bef05-61-502'bef06-60-502'bef08-60-502'bef10-60-502，bef10-61-502，bef12-60-502，bef12-61-502，bef14-60-502，bef16-60-502，bef16-61-502，bef18-60-502，bef20-60-502，bef22-60-502，bef25-60-502，bef30-60-502��bef30-61-502; bef05-90-502，bef05-91-502，bef06-90-502，bef08-90-502，bef10-90-502，bef10-91-502，bef12-90-502，bef12-91-502，bef14-90-502，bef16-90-502，bef16-91-502，bef18-90-502，bef20-90-502，bef22-90-502，bef25-90-502，bef30-90-502，bef30-91-502; Bef1 / 4-20-502, bef3 / 8-20-502, bef1 / 2-20-502, bef5 / 8-20-502, bef3 / 4-20-502, bef1 / 1-20-502, bef1 / 1-21-502 EM series are external thread oil-free joint bearings, and the details are as follows:Br >

Internal thread oil-free joint bearing, specific model package Including: ef06-20-501, ef08-20-501, ef10-20-501, ef10-21-501, ef12-20-501, ef12-21-501, ef15-20-501, ef17-20-501, ef17-21-501, ef20-20-501, ef25-20-501, ef30-20-501, ef35-20-501, ef35-21-501, ef35-21-501, ef40-20-501, ef40-21-501, ef45-20-501, ef45-20-501, ef45-21-501, ef50-20-501, ef50-21-501, ef60-20-501, ef60-20-501,60-21-501 ef06-20-502, ef08-20-502, ef10-20-502, ef10-21-502, ef12-20-502, ef12-21-502, ef12-21-502, ef15-20-502, ef17-20-502, ef17-21-502, ef20-20-502, ef20-20-502, ef25-20-502, ef30-20-502, ef35-20-502, ef35-21-502, ef40-20-502, ef40-20-502, ef40-21-502, ef45-20-502, ef45-21-502, ef45-21-502 50-20-502, ef50-21-502, ef60-20-502, ef60-21-502

Shenzhen Weisheng Machinery Co., Ltd. is a trading company specializing in imported bearings and industrial products. Its products are applied in coal mines, machinery manufacturing, electric power, papermaking, textile, petrochemical, iron and steel metallurgy and other industries. in order to provide better quality services to users faster, the company adheres to the business philosophy of "integrity-based and quality", Promise to sell products --- original!

the company is the authorized agent of getecno company in Italy, which owns rodobal, rodoflex, rodogrip and rodoset. Rodobal produces various kinds of joint bearings and has a complete range of products in the field of joint bearings. In particular, the stainless steel joint bearings produced by the company are widely used in the food processing industry and the marine shipping industry in addition to the industry. As for the joint bearing with screw, in addition to ordinary pitch, it can also provide products with fine pitch. Rodoflex is a precision coupling, rodogrip is a precision locking ring and rodoset is an adjustable gasket.

at the same time, our company is also the authorized agent of SNR bearing in France, with a large number of spot supply and price advantage!

main advantages:

1. France SNR bearing, Italy rodobal joint bearing authorized agent, price advantage! 2. SKF (large quantity of stock) ina special price supply (Hong Kong stock 3-5 days, Singapore stock 10 days, Europe stock 2-3 days)Zhou), accept the futures booking, price concessions! 3. German SWC high-temperature bearing, Swiss sferax high-precision linear bearing, German GRW high-precision bearing, American kaydon bearing, Japanese NB linear bearing 4. European and American imported bearing difficult and short models of futures, the positive price is excellent!

trust us! You can not find the products, we will solve for you, Let the machine run smoothly!

there is no product that can not be found, only the waiting time!

there is no product that can not be bought, only the price that is difficult to accept!

please write in the inquiry: brand, product model, quantity and other information, fax or e-mail to us directly, and we will reply within 1-3 days, Br > e-mail:[email protected]

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furniture</a>dgiho-k16do〉〈dgiho-k20do〉〈dgiho-k25do〉〈dgiho-k30do〉〈dgiho-k50do〉〈dgiho-k60do〉〈dgihr20do〉〈dgihr25do〉〈dgihr30do〉〈dgihr35do〉〈dgihr40do〉〈dgihr50do〉〈dgihr60do〉〈dgihr70do〉〈dgihr80do〉〈dgihr-k20do〉〈dgihr-k25do〉〈dgihr-k30do〉〈dgihr-k35do〉〈dgihr-k40do〉〈dgihr-k50do〉〈dgihr-k60do〉〈dgihr-k70do〉〈dgihr-k80do〉〈dgil06uk〉〈dgil08uk〉〈dgil10uk〉〈dgil12uk〉〈dgil15uk〉〈dgil17uk〉〈dgil17uk-2rs〉〈dgil20uk〉〈dgil20uk-2rs〉〈dgil25uk〉〈dgil25uk-2rs〉〈dgil30uk〉〈dgil30uk-2rs〉〈dgil35uk-2rs〉〈dgil40uk-2rs〉〈dgil45uk-2rs〉〈dgil50uk-2rs〉〈dgil60uk-2rs〉〈dgil70uk-2rs〉〈dgil80uk-2rs〉〈dgir06uk〉〈dgir08uk〉〈dgir10uk〉〈dgir12uk〉〈dgir15uk〉〈dgir17uk〉〈dgir17uk-2rs〉〈dgir20uk〉〈dgir25uk〉〈dgir25uk-2rs〉〈dgir30uk〉〈dgir30uk-2rs〉〈dgir35uk-2rs〉〈dgir45uk-2rs〉〈dgir50uk-2rs〉〈dgir50uk-2rsm52x〉〈dgir60uk-2rs〉〈dgir70uk-2rs〉〈dgir80uk-2rs〉〈dgk10do〉〈dgk12do〉〈dgk15do〉〈dgk17do〉〈dgk20do〉〈dgk25do〉〈dgk25sk〉〈dgk30do〉〈dgk30sk〉〈dgk35do〉〈dgk35sk〉〈dgk40do〉〈dgk45do〉〈dgk50do〉〈dgk50sk〉〈dgk60do〉〈dgk70do〉〈dgk80do〉〈dgs1〉〈dgs2〉〈dgs3〉〈dgs4〉〈dgs5〉〈dphs05〉〈dphs05m4x0,7〉〈dphs06〉〈dphs08〉〈dphs10〉〈dphs10m10x1,25〉〈dphs12〉〈dphs12m12x1,25〉〈dphs14〉〈dphs14m14x1,5〉〈dphs16〉〈dphs16m16x1,5〉〈dphs18〉〈dphs20〉〈dphs22〉〈dphs25〉〈dphs30〉〈dphs30m27x2〉〈dphsl05〉〈dphsl06〉〈dphsl08〉〈dphsl10〉〈dphsl10m10x1,25〉〈dphsl12〉〈dphsl12m12x1,25〉〈dphsl14〉〈dphsl14m14x1,5〉〈dphsl16〉〈dphsl18〉〈dphsl20〉〈dphsl22〉〈dphsl25〉〈dphsl30〉〈dpos05〉〈dpos06〉〈dpos08〉〈dpos10〉〈dpos12〉〈dpos14〉〈dpos16〉〈dpos18〉〈dpos20〉〈dpos22〉〈dpos25〉〈dpos30〉〈dposl05〉〈dposl06〉〈dposl08〉〈dposl10〉〈dposl12〉〈dposl14〉〈dposl16〉〈dposl18〉〈dposl20〉〈dposl22〉〈dposl25〉〈dposl30〉〈ds08pb〉〈ds08pw〉〈ds10pb〉〈ds10pw〉〈ds12pb〉〈ds12pw〉〈ds14pb〉〈ds14pw〉〈ds16pb〉〈ds20pb〉〈ds20pw〉〈ds22pb〉〈ds25pb〉〈ds25pw〉〈ds30pb〉〈ds30pw〉〈dsa05t/k〉〈dsa06e〉〈dsa06t/k〉〈dsa08e〉〈dsa08t/k〉〈dsa10e〉〈dsa10t/k〉〈dsa10t/km10x1,2〉〈dsa12e〉〈dsa12t/k〉〈dsa12t/km12x1,2〉〈dsa14t/k〉〈dsa15es〉〈dsa15es-2rs〉〈dsa16t/k〉〈dsa16t/km16x1,5〉〈dsa17es〉〈dsa17es-2rs〉〈dsa18t/k〉〈dsa20es〉〈dsa20es-2rs〉〈dsa20t/k〉〈dsa22t/k〉〈dsa25es〉〈dsa25es-2rs〉〈dsa25t/k〉〈dsa25t/k-01〉〈dsa30es〉〈dsa30es-2rs〉〈dsa30t/k〉〈dsa35es〉〈dsa35t/k〉〈dsa40es〉〈dsa40es-2rs〉〈dsa40t/k〉〈dsa45es-2rs〉〈dsa50es〉〈dsa50es-2rs〉〈dsa60es〉〈dsa60es-2rs〉〈dsa70es〉〈dsa70es-2rs〉〈dsa80es〉〈dsa80es-2rs〉〈dsal05t/k〉〈dsal06e〉〈dsal06t/k〉〈dsal08e〉〈dsal08t/k〉〈dsal10e〉〈dsal10t/k〉〈dsal10t/km10x1,〉〈dsal12e〉〈dsal12t/k〉〈dsal12t/km12x1,〉〈dsal14t/k〉〈dsal15es〉〈dsal15es-2rs〉〈dsal16t/k〉〈dsal16t/km16x1,〉〈dsal17es〉〈dsal17es-2rs〉〈dsal18t/k〉〈dsal20es〉〈dsal20es-2rs〉〈dsal20t/k〉〈dsal22t/k〉〈dsal25es〉〈dsal25es-2rs〉〈dsal25t/k〉〈dsal30es〉〈dsal30es-2rs〉〈dsal30t/k〉〈dsal35es〉〈dsal35es-2rs〉〈dsal40es〉〈dsal40es-2rs〉〈dsal40t/k〉〈dsal45es〉〈dsal45es-2rs〉〈dsal50es〉〈dsal50es-2rsm52x〉〈dsal50t/k〉〈dsal60es〉〈dsal60es-2rs〉〈dsal70es〉〈dsal70es-2rs〉〈dsal80es〉〈dsal80es-2rs〉〈dsazp06s〉〈dsazp11s〉〈dsazp15s〉〈dsazpl15s〉〈dsazpl19s〉〈dsg05pb〉〈dsg06pb〉〈dsg08pb〉〈dsg10pb〉〈dsg12pb〉〈dsg14pb〉〈dsg16pb〉〈dsg18pb〉〈dsg20pb〉〈dsg22pb〉〈dsg25pb〉〈dsg30pb〉〈dsge06uk〉〈dsge08uk〉〈dsge10uk〉〈dsge12uk〉〈dsge15uk〉〈dsge17uk〉〈dsge20uk〉〈dsge25uk〉〈dsi05t/k〉〈dsi05t/km4〉〈dsi06e〉〈dsi06t/k〉〈dsi08e〉〈dsi08t/k〉〈dsi10e〉〈dsi10t/k〉〈dsi10t/km10x1,2〉〈dsi12e〉〈dsi12t/k〉〈dsi12t/km12x1,2〉〈dsi14t/k〉〈dsi14t/km14x1,5〉〈dsi15es〉〈dsi15es-2rs〉〈dsi16t/k〉〈dsi16t/km16x1,5〉〈dsi17es〉〈dsi17es-2rs〉〈dsi18t/k〉〈dsi20es〉〈dsi20es-2rs〉〈dsi20t/k〉〈dsi22t/k〉〈dsi25es〉〈dsi25es-2rs〉〈dsi25t/k〉〈dsi30es〉〈dsi30es-2rs〉〈dsi30t/k〉〈dsi30t/km27x2〉〈dsi35es〉〈dsi35es-2rs〉〈dsi35t/k〉〈dsi40es〉〈dsi40t/k〉〈dsi45es〉〈dsi50es〉〈dsi50t/k〉〈dsi60es〉〈dsi60es-2rs〉〈dsi70es〉〈dsi70es-2rs〉〈dsi80es〉〈dsi80es-2rs〉〈dsil05t/k〉〈dsil06e〉〈dsil06t/k〉〈dsil08e〉〈dsil08t/k〉〈dsil10e〉〈dsil10t/k〉〈dsil10t/km10x1,〉〈dsil12e〉〈dsil12t/k〉〈dsil12t/km12x1,〉〈dsil14t/k〉〈dsil14t/km14x1,〉〈dsil15es〉〈dsil15es-2rs〉〈dsil16t/k〉〈dsil17es〉〈dsil17es-2rs〉〈dsil18t/k〉〈dsil20es〉〈dsil20es-2rs〉〈dsil20t/k〉〈dsil22t/k〉〈dsil25es-2rs〉〈dsil25t/k〉〈dsil30es〉〈dsil30es-2rs〉〈dsil30t/k〉〈dsil30t/km27x2〉〈dsil35es〉〈dsil35es-2rs〉〈dsil35t/k〉〈dsil40es〉〈dsil40t/k〉〈dsil45es〉〈dsil45es-2rs〉〈dsil50es〉〈dsil50es-2rs〉〈dsil60es〉〈dsil60es-2rs〉〈dsil70es〉〈dsil70es-2rs〉〈dsil80es〉〈dsil80es-2rs〉〈dsizj11〉〈dsizp04s〉〈dsizp06s〉〈dsizp07s〉〈dsizp09s〉〈dsizp11s〉〈dsizp15s〉〈dsizp19s〉〈dsizp25s〉〈dsizpl04s〉〈dsizpl06s〉〈dsizpl07s〉〈dsizpl09s〉〈dsizpl11s〉〈dsizpl12s〉〈dsizpl15s〉〈dsizpl19s〉〈dssa05t/k〉〈dssa06t/k-b〉〈dssa08t/k〉〈dssa08t/k-b〉〈dssa10t/k-b〉〈dssa12t/k〉〈dssa12t/km12x1,〉〈dssa14t/k〉〈dssa14t/k-b〉〈dssa16t/k〉〈dssa16t/km16x1,〉〈dssa16t/k-b〉〈dssa18t/k〉〈dssa18t/k-b〉〈dssa20t/k〉〈dssa25t/k〉〈dssa12tkm12x1,25b〉〈dssal05t/k〉〈dssal05t/k-b〉〈dssal06t/k〉〈dssal08t/k〉〈dssal10t/k〉〈dssal10t/k-b〉〈dssal12t/k〉〈dssal12t/k-b〉〈dssal14t/k〉〈dssal16t/km16x1〉〈dssal18t/k-b〉〈dssal20t/k〉〈dssal20t/k-b〉〈dssal25t/k〉〈dssal12t/km12x1,2〉〈dssi05t/k〉〈dssi06t/k〉〈dssi06t/k-b〉〈dssi10t/k〉〈dssi10t/k-b〉〈dssi12t/k〉〈dssi12t/km12x1,〉〈dssi12t/k-b〉〈dssi14t/k〉〈dssi14t/km14x1,〉〈dssi14t/k-b〉〈dssi16t/k〉〈dssi18t/k-b〉〈dssi20t/k〉〈dssi25t/k〉〈dssil05t/k〉〈dssil05t/k-b〉〈dssil06t/k〉〈dssil06t/k-b〉〈dssil08t/k〉〈dssil08t/k-b〉〈dssil10t/k〉〈dssil10t/k-b〉〈dssil12t/k〉〈dssil12t/km12x1〉〈dssil12t/k-b〉〈dssil14t/k-b〉〈dssil16t/k〉〈dssil16t/k-b〉〈dssil18t/k〉〈dssil18t/k-b〉〈dssil20t/k〉〈dssil25t/k〉〈dssil10tkm10x1,25b〉〈dssil12t/km12x1,2〉〈dssil14t/km14x1,5〉〈dssil16t/km16x1,5〉〈ef06-20-501〉〈ef06-20-502l〉〈ef06-60-501〉〈ef06-60-502l〉〈ef08-20-501〉〈ef08-20-502l〉〈ef08-60-501〉〈ef08-60-502l〉〈ef10-20-501〉〈ef10-20-502l〉〈ef10-21-501〉〈ef10-21-502l〉〈ef10-60-501〉〈ef10-60-502l〉〈ef10-61-501〉〈ef10-61-502l〉〈ef12-20-501〉〈ef12-20-502l〉〈ef12-21-501〉〈ef12-21-502l〉〈ef12-60-501〉〈ef12-60-502l〉〈ef12-61-501〉〈ef12-61-502l〉〈ef15-20-501〉〈ef15-20-502l〉〈ef15-60-501〉〈ef15-60-502l〉〈ef17-20-501〉〈ef17-20-502l〉〈ef17-60-501〉〈ef17-60-502l〉〈ef20-20-501〉〈ef20-20-502l〉〈ef20-60-501〉〈ef20-60-502l〉〈ef25-20-501〉〈ef25-20-502l〉〈ef30-20-501〉〈ef30-20-502l〉〈ef35-20-501〉〈ef35-20-502l〉〈ef35-21-502l〉〈ef40-20-501〉〈ef40-20-502l〉〈ef40-21-501〉〈ef40-21-502l〉〈ef45-20-501〉〈ef45-20-502l〉〈ef45-21-501〉〈ef50-20-501〉〈ef50-20-502l〉〈ef50-21-501〉〈ef50-21-502l〉〈ef60-20-501〉〈ef60-20-502l〉〈ef60-21-501〉〈ef60-21-502l〉〈efn06-20-501〉〈efn06-20-502l〉〈efn08-20-501〉〈efn08-20-502l〉〈efn10-20-501〉〈efn10-20-502l〉〈efn10-21-501〉〈efn12-20-501〉〈efn12-20-502l〉〈efn12-21-501〉〈efn12-21-502l〉〈efn15-20-501〉〈efn15-20-502l〉〈efn17-20-501〉〈efn17-20-502l〉〈efn20-20-501〉〈efn20-20-502l〉〈efn20-30-501〉〈efn20-30-502l〉〈efn25-20-501〉〈efn25-20-502l〉〈efn30-20-501〉〈efn30-20-502l〉〈efn30-30-502l〉〈efn35-30-501〉〈efn35-30-502l〉〈efn40-30-501〉〈efn40-30-502l〉〈efn45-20-501〉〈efn45-30-501〉〈efn45-30-502l〉〈efn50-30-502l〉〈em06-20-501〉〈em06-20-502l〉〈em06-60-501〉〈em06-60-502l〉〈em08-20-502l〉〈em08-60-501〉〈em08-60-502l〉〈em10-20-501〉〈em10-20-502l〉〈em10-60-501〉〈em10-60-502l〉〈em12-20-501〉〈em12-20-502l〉〈em12-60-501〉〈em12-60-502l〉〈em15-20-501〉〈em15-20-502l〉〈em15-60-501〉〈em15-60-502l〉〈em17-20-501〉〈em17-20-502l〉〈em17-60-501〉〈em17-60-502l〉〈em20-20-501〉〈em20-20-502l〉〈em20-60-501〉〈em20-60-502l〉〈em25-20-501〉〈em25-20-502l〉〈em30-20-501〉〈em30-20-502l〉〈em35-20-501〉〈em35-20-502l〉〈em40-20-501〉〈em40-20-502l〉〈em40-21-501〉〈em40-21-502l〉〈em45-20-501〉〈em45-20-502l〉〈em45-21-501〉〈em45-21-502l〉〈em50-20-501〉〈em50-20-502l〉〈em50-21-501〉〈em50-21-502l〉〈em50-23-501〉〈em50-23-502l〉〈em50-60-501〉〈em50-60-502l〉〈em60-20-501〉〈em60-20-502l〉〈em60-21-501〉〈em60-21-502l〉〈emn06-20-501〉〈emn06-20-502l〉〈emn08-20-501〉〈emn08-20-502l〉〈emn10-20-501〉〈emn10-20-502l〉〈emn12-20-501〉〈emn12-20-502l〉〈emn15-20-501〉〈emn15-20-502l〉〈emn17-20-501〉〈emn17-20-502l〉〈emn20-20-501〉〈emn20-20-502l〉〈emn20-30-501〉〈emn20-30-502l〉〈emn25-20-501〉〈emn25-20-502l〉〈emn25-30-501〉〈emn25-30-502l〉〈emn30-20-501〉〈emn30-20-502l〉〈emn35-20-502l〉〈emn35-30-501〉〈emn50-30-501〉〈gle25-20-500〉〈gle30-20-500〉〈gw08-00-001〉〈gw08-00-002〉〈gw08-01-001〉〈gw08-01-002〉〈gw10-00-001〉〈gw10-00-002〉〈gw10-01-001〉〈gw10-01-002〉〈gw12-00-001〉〈gw12-00-002〉〈gw12-01-001〉〈gw12-01-002〉〈gw14-00-001〉〈gw14-00-002〉〈gw14-01-001〉〈gw14-01-002〉〈gw16-00-001〉〈gw16-00-002〉〈gw16-01-001〉〈gw16-01-002〉〈gw20-00-001〉〈gw20-00-002〉〈gw24-01-002〉〈gw30-00-001〉〈gw30-00-002〉〈h-dg12x48m12x1,2〉〈h-dg25x50〉〈pf10-00-501〉〈pf10-00-502l〉〈pf15-00-501〉〈pf15-00-502l〉〈pf20-00-501〉〈pf20-00-502l〉〈pi+se25〉〈pi+se30〉〈pi+se35〉〈pm06-00-501〉〈pm06-00-502l〉〈pm06-01-501〉〈pm06-01-502l〉〈pm08-00-501〉〈pm08-00-502l〉〈pm08-01-501〉〈pm08-01-502l〉〈pm10-00-501〉〈pm10-00-502l〉〈pm10-01-501〉〈pm10-01-502l〉〈pm10-03-501〉〈pm10-03-502l〉〈pm12-00-501〉〈pm12-00-502l〉〈pm12-01-501〉〈pm12-01-502l〉〈pm15-00-501〉〈pm15-00-502l〉〈pm15-01-501〉〈pm17-00-501〉〈pm17-00-502l〉〈pm17-01-502l〉〈pm20-00-501〉〈pm20-00-502l〉〈pm20-01-502l〉〈wlk06-00-500〉〈wlk08-00-500〉〈wlk10-00-500〉〈wlk12-00-500〉〈wlk16-00-500〉〈wlk18-00-500〉〈wlk20-00-500〉〈wlk22-00-500〉〈wlk25-00-500〉〈wlk30-00-500〉〈wlt12-00-500〉〈wlt12-30-500〉〈wlt16-00-500〉〈wlt16-30-500〉〈wlt20-00-500〉〈wlt20-30-500〉〈wlt25-00-500〉〈wlt25-30-500〉〈wlt30-30-500〉〈05-00-936-1〉〈05-00-936-2〉〈05-60-936-1〉〈05-60-936-2〉〈06-00-936-1〉〈06-00-936-2〉〈06-60-936-1〉〈06-60-936-2〉〈08-00-936-1〉〈08-00-936-2〉〈08-60-936-1〉〈08-60-936-2〉〈1/1-00-936-1〉〈1/1-00-936-2〉〈1/1-01-936-1〉〈1/1-01-936-2〉〈1/2-00-936-1〉〈1/2-00-936-2〉〈1/4-00-936-1〉〈1/4-00-936-2〉〈10-00-936-1〉〈10-00-936-2〉〈10-01-936-1〉〈10-01-936-2〉〈10-01-961-1〉〈10-02-936-1〉〈10-02-936-2〉〈10-60-936-1〉〈10-60-936-2〉〈10-61-936-1〉〈12-00-936-1〉〈12-00-936-2〉〈12-01-936-1〉〈12-01-936-2〉〈12-02-936-1〉〈12-02-936-2〉〈12-60-934-1〉〈12-60-934-2〉〈12-60-936-1〉〈12-60-936-2〉〈12-61-936-1〉〈14-00-936-1〉〈14-00-936-2〉〈14-01-936-1〉〈14-01-936-2〉〈16-00-936-1〉〈16-00-936-2〉〈16-01-936-1〉〈16-01-936-2〉〈16-60-936-1〉〈16-60-936-2〉〈16-61-936-1〉〈16-61-936-2〉〈18-01-936-1〉〈18-01-936-2〉〈18-61-439-1〉〈20-01-936-1〉〈20-01-936-2〉〈20-61-936-1〉〈22-01-936-1〉〈22-01-936-2〉〈22-61-936-1〉〈22-61-936-2〉〈24-01-936-1〉〈24-01-936-2〉〈24-02-936-1〉〈24-02-936-2〉〈24-60-936-1〉〈24-61-936-1〉〈24-61-936-2〉〈27-01-936-1〉〈3/4-00-936-1〉〈3/4-00-936-2〉〈3/8-00-936-1〉〈3/8-00-936-2〉〈30-01-936-1〉〈30-01-936-2〉〈36-01-936-1〉〈36-01-936-2〉〈39-01-936-1〉〈39-01-936-2〉〈42-01-936-1〉〈42-befn-06-06-20-501〉〈〈befn-06-20-502l〉〈〈〈befn-06-06-80-80-501〉;〈;〈befn-06-06-20-501〉;〈;〈befn-06-20-501〉;〈;〈befn-08-08-20-502I〉;〈befn-08-08-80-501 z;〈 befn-08-08-80-501 z;;〈 befn-08-08-80-501 z;;;〉〈 befn-08-90-501〉〈befn-08-90-502l〉〈befn-10-20-501〉〈befn-10-20-502l〉〈befn-10-21-501〉〈befn-10-80-501〉〈befn-10-80-502l〉〈befn-10-81-501〉〈be I'm-12-12-20-501〉〈〈〈;〈;〈;;〈;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;12297;〈befn-14-20-502l〉〈befn-16-20-501〉〈befn-16-20-502l〉〈befn-16-21-501〉〈befn-16-21-502l〉;〈befn-16-16-80-502l〉〈;〈befn-16-16-81-501〉;〈;〈;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;12296;befn-20-502l〉〈befn-20-80-501〉〈befn-20-80-502l〉〈befn-22-20-502l〉〈befn-22-80-502l〉〈befn-25-20-501〉〈befn-25-20-501〉〈befn-25-20-502l〉〈befn-30- 20-501;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;06-20-502l〉〈well-06-60-501〉〈well-06-60-502l〉〈well-08-20-501〉〈well-08-20-502l〉〈well-08-20-502l〉〈well-08m-20-20-60-502l〉;〈well-22-22-20-501〉〈〈;〈;〈;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;well-25-90-501〉〈well-25-90-502l〉〈well-3/4-20-501〉〈well-3/4-20-502l〉〈well-3/8-20-502l〉〈well-3/8-20-502l〉〈well-30-20-501〉〈well-30-20-502l〉〈well-30-60-501 〉〉〉〈〈〈〈〈〈〈〈〈〈〈〈〈〈〈 \12296; \12296; \12296; \12296; \12296; \12296; \12296; \\〈 \〈 \12296; \12296; \12296; \\ \\12296; \\ \\ \\\ \\\ \ a〈bemn-06-80-501〉〈bemn-06-80-502l〉〈bemn-08-20-501〉〈bemn-08-20-502l〉〈bemn-08-80-501〉〈bemn-1〉〈brf-06-60-502l〉〈brf-08-00-501〉〈brf-08-00-502l〉〈brf-08-60-501〉〈brf-08-60-502l〉〈brf-1/1-00-501〉〈brf-1/1-00-502l〉〈brf-1/1-01-501〉〈brf-1/1-01-502l〉〈brf-1/2-00-501〉〈brf-1/2-00-502l〉〈brf-1/4-00-501〉〈brf-1/4-00-502l〉〈brf-10-00-501〉〈brf-10-00-502l〉〈brf-10-01-501〉〈brf-10-01-502l〉〈brf-10-60-502l〉〈brf-10-61-501〉〈brf-12-00-501〉〈brf-12-00-502l〉〈brf-12-01-501〉〈brf-12-01-502l〉〈brf-12-60-501〉〈brf-12-60-502l〉〈brf-14-00-501〉〈brf-14-00-502l〉〈brf-16-00-501〉〈brf-16-00-502l〉〈brf-16-01-501〉〈brf-16-01-502l〉〈brf-16-60-501;0-501〉〈;〈brf-16-16-60-502I〉〈〈brf-16-16-61-61-501〉〈〈;〈;;〈;;〈;;〈;;〈;;〈;;〈;;;〈;;????????12212296;;;;;- 22-22-22-00-DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD; brf-30-00-501〉〈brf -30-00-502l〉〈brf-5/8-00-501〉〈brf-5/8-00-502l〉〈brm-06-00-501〉〈brm-06-00-502l〉〈brm-08-00-501〉〈brm-08-00-502l〉〈brm-08-60-502l〉〈brm-1/1-00-501〉〈brm-1/1-00-502l〉〈brm-1/1-01-501〉〈brm-1/1-01-502l〉〈brm-1/2-00-501〉〈brm-1/2-00-502l〉〈brm-1/4-00-501〉〈brm-1/4-00-502l〉〈brm-10-00-501〉〈brm-10-00-502l〉〈brm-10-60-501〉〈brm-10-60-502l〉〈brm-12-00-501〉〈brm-12-00-502l〉〈brm-12-60-502l〉〈brm-14-00-501〉〈brm-14-00-502l〉〈brm-16-00-501〉〈brm-16-00-502l〉〈brm-16-60-501〉〈brm-16-60-502l〉〈brm-18-00-501〉〈brm-18-00-502l〉〈brm-20-00-501〉〈brm-20-00-502l〉〈brm-20-60-501〉〈brm-20-60-502l〉〈brm-22-00-501〉〈brm-22-00-502l〉〈brm-25-00-501〉〈brm-25-00-502l〉〈brm-3/4-00-501〉〈brm-3/4-00-502l〉〈brm-3/8-00-501〉〈brm-3/8-00-502l〉〈brm-30-00-501〉〈brm-30-00-502l〉〈brm-5/8-00-501〉〈brm-5/8-00-502l〉〈brtf-1/1-00-501〉〈brtf-1/1-00-502l〉〈brtf-1/1-01-501〉〈brtf-1/1-01-502l〉〈brtf-1/2-00-501〉〈brtf-1/2-00-502l〉〈brtf-12-00-501〉〈brtf-12-00-502l〉〈brtf-12-01-501〉〈brtf-12-01-502l〉〈brtf-12-30-501〉〈brtf-12-30-502l〉〈brtf-16-00-501〉〈brtf-16-00-502l〉〈brtf-16-01-501〉〈brtf-16-01-502l〉〈brtf-16-30-501〉〈brtf-16-30-502l〉〈brtf-20-00-501〉〈brtf-20-30-501〉〈brtf-20-30-502l〉〈brtf-20-60-502l〉〈brtf-25-00-501〉〈brtf-25-00-502l〉〈brtf-25-30-501〉〈brtf-25-30-502l〉〈brtf-3/4-00-501〉〈brtf-3/4-00-502l〉〈brtf-3/4-01-501〉〈brtf-30-00-501〉〈brtf-30-00-502l〉〈brtf-30-30-501〉〈brtf-30-30-502l〉〈brtf-35-00-501〉〈brtf-35-00-502l〉〈brtf-35-30-501〉〈brtf-35-30-502l〉〈brtf-40-00-501〉〈brtf-40-30-501〉〈brtf-5/8-00-501〉〈brtf-5/8-00-502l〉〈brtm-1/1-00-501〉〈brtm-1/1-00-502l〉〈brtm-1/1-01-501〉〈brtm-1/1-01-502l〉〈brtm-1/2-00-501〉〈brtm-1/2-00-502l〉〈brtm-12-00-501〉〈brtm-12-00-502l〉〈brtm-12-30-501〉〈brtm-12-30-502l〉〈brtm-16-00-501〉〈brtm-16-00-502l〉〈brtm-16-30-501〉〈brtm-16-30-502l〉〈brtm-20-00-501〉〈brtm-20-00-502l〉〈brtm-20-30-501〉〈brtm-20-30-502l〉〈brtm-20-31-501〉〈brtm-25-00-501〉〈brtm-25-00-502l〉〈brtm-25-30-501〉〈brtm-25-30-502l〉〈brtm-3/4-00-501〉〈brtm-3/4-00-502l〉〈brtm-30-00-501〉〈brtm-30-00-502l〉〈brtm-30-30-501〉〈brtm-30-30-502l〉〈brtm-35-00-501〉〈brtm-35-00-502l〉〈brtm-35-30-501〉〈brtm-35-30-502l〉〈brtm-40-00-501〉〈brtm-40-00-502l〉〈brtm-40-30-501〉〈brtm-5/8-00-501〉〈brtm-5/8-00-502l〉〈brtm-5/8-30-501〉〈dcs-08-m5x0,8〉〈dcs-10-m6x1,0〉〈dcs-10-m6x1,0-rs〉〈dcs-13-m8x1,25〉〈dcs-13-m8x1,25-rs〉〈dcs-16-m10x1,5〉〈dcs-16-m12x1,75〉〈dcs-19-m14x1,5〉〈dcs-19-m14x2,0〉〈dcs-19-m16〉〈dcsl-08-m5x0,8〉〈dcsl-10-m6x1,0〉〈dcsl-13-m8x1,25〉〈dcsl-16-m10x1,5〉〈dcsl-16-m12x1,75〉〈dcsl-19-m14x1,5〉〈dcsl-19-m14x2,0〉〈dcsl-19-m16〉〈ddg-05-00-100〉〈ddg-06-00-100〉〈ddg-08-00-100〉〈ddg-10-00-100〉〈ddg-12-00-100〉〈ddg-14-00-100〉〈ddg-16-00-100〉〈ddg-18-00-100〉〈ddg-20-00-100〉〈ddg-25-00-100〉〈ddg-30-00-100〉〈dfkb-06x12〉〈dfkb-08x16〉〈dfkb-10x20〉〈dfkb-10x40〉〈dfkb-12x24〉〈dfkb-12x48〉〈dfkb-14x28〉〈dfkb-14x56〉〈dfkb-16x32〉〈dfkb-16x64〉〈dfkb-20x40〉〈dg-04x08〉〈dg-04x16〉〈dg-05-pb〉〈dg-05-pw〉〈dg-05x10〉〈dg-05x20〉〈dg-06-pb〉〈dg-06-pw〉〈dg-06x12〉〈dg-06x24〉〈dg-08-pb〉〈dg-08-pw〉〈dg-08x16〉〈dg-08x16-m8x1,0〉〈dg-08x32〉〈dg-08x32-m8x1, 0 > dg-10-pb > dg-10-pw

price of German Durbar bearing, manufacturer of German Durbar bearing, parameter of German Durbar bearing

when contacting us, please make sure you see this information on the website of 100 merchants, thank you!

Tel: 138236717500755-22361750, welcome to inquire!

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key words: SNR bearing - Dodge bearing - sferax bearing - SWC bearing - kaydon bearing

provide Pingliang with good faith to deliver goods free of charge to the distribution station of Jilin logistics company. Pingliang to Jilin logistics company business oriented logistics company, 24-hour serviceBusiness hotline; 135-2224-3495 contact person; manager Liu our company is a regular freight company engaged in the transportation of general goods approved by the Administration for Industry and Commerce and registered with the transportation administration.

since its establishment, the company has always adhered to customer-oriented, committed to building an efficient and reliable freight company.

the company is equipped with hundreds of large, medium and small transport vehicles to meet all kinds of transportation conditions, and also provides all aspects of logistics services such as packaging, storage, distribution, etc.

the company adheres to the business philosophy of "treating people sincerely, doing things practically, cooperating for win-win results and seeking common development", It advocates the corporate culture of "health, happiness and integrity", takes "being practical, strong, big and long-term" as the development strategy of the enterprise, takes "safe and convenient, customers, scientific management and high-quality service" as the service tenet, takes safeguarding customers' interests as the foothold, strengthens internal quality, shapes external image, strictly manages, innovates and develops, and is willing to work together with new and old friends to create a better future Come on.

I logistics - as a participant in the logistics industry, we have a special feeling for logistics, so we always keep a single mind.

specialization can win trust; specialization can keep innovating; specialization can keep breaking through; specialization can keep developing; specialization can make development and build brand; brand is trustworthy. L

main business scope:

1. Transportation business of all kinds of complete vehicles and zero load goods;

2. Storage, temporary storage, transit and distribution of all kinds of goodsDelivery business;

3. Insurance business of all kinds of goods transportation;

4. All kinds of goods are packed and ordered to be fully closed, semi closed, cartons and wooden boxes;

5. Provide all kinds of moving, moving and goods consignment services for individuals and companies;

6. Transportation of valuables, exhibition materials and fragile goods in soft packaging;

7. Transportation of large quantities of materials and large equipment;

< 8. Transportation of various cars;

Freight Co., Ltd. has a group of young, full of vigor and vitality of employees who are proficient in information management. Z

for many years, the company has provided intellectual support for building "young, information and brand" freight service. The company has been active in the first place of freight industry in China with scientific management, standardized service, reasonable transportation price and good corporate reputation.

to undertake the national road freight transportation, we have realized the crisscross and real three-dimensional freight express between cities nationwide by virtue of the powerful information service platform and network advantages, and can provide customers with direct door-to-door and door-to-door distribution business.

combine the special line transportation according to certain standards and requirements, gather a system operation platform and share the platform goods source!

the logistics company of Freight Co., Ltd. serves you 24 hours a day. The company has the advantage that no matter how many goods are, one person is responsible for one ticket of goodsIn the end, it will make it easier for you to track the goods, adhere to the spirit of "honesty, dedication, pioneering and enterprising", with the concept of "honesty, speed, development and dedication", with the management idea, excellent management practice and the use of modern logistics management technology, the company has the advantages of transportation and storage to provide customers with value-added services.

there is a long way to go in a thousand miles, and all things are connected with virtue! Our company has dozens of transportation vehicles, such as 4.2m, 6.8m, 9.6m, 12.5m, 17.5m ordinary vehicles, high rail vehicles, containers, etc.:

a zero load transport vehicle: safer, faster, more affordable, more convenient; suitable for all kinds of small, bulk and zero load goods transportation.

b a light truck with a capacity of less than 5 tons, with a length of 4 meters and a width of 1.8 meters, can carry all kinds of non dangerous goods under 5 tons and within 15 cubic meters for you. It is an urgent and valuable goods transport.

C a medium-sized truck with a capacity of less than 10 tons, with a length of 6 meters and a width of 2 meters, can carry all kinds of non dangerous goods with a capacity of less than 10 tons and less than 30 cubic meters for you, which is safer, safer and more valuable.

d a medium truck with a load capacity of less than 18 tons, with a length of 9.6 meters and a width of 2.2 meters, can carry all kinds of non dangerous goods of less than 18 tons and less than 50 cubic meters for you.

e a large truck with a capacity of less than 38 tons, with a length of 13 meters and a width of 2.2 meters, can carry all kinds of non dangerous goods under 38 tons and less than 70 cubic meters for you. It is a transportation of all kinds of bulk goodsOf.

f a large truck with a capacity of less than 35t, with a length of 17. M and a width of 2.8m, can carry all kinds of non dangerous goods below 35t for you, and is more suitable for the transportation of various machines, equipment, super long and super wide logistics.

our logistics team will help you plan an effective, reasonable and --- logistics distribution plan. J

make sure your goods arrive faster and more quickly.

among the numerous logistics companies, my freight is your choice.

unity, dedication, integrity and enterprising!

Pingliang to Jilin Logistics Co., Ltd. 24-hour contact hotline 13522243495 contact person; manager Liu

when contacting us, please make sure that you see this information on the 100 merchants website, thank you!

Tel: transportation line, 13522243495, welcome to inquire!

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