#TEDMED

[pwrn51]

Micro-Skills Magic: Improve Your Life and Business

    We’re excited to have Dr. Resa E. Lewiss join us today! She is the co-author of “MICRO SKILLS: SMALL ACTIONS, BIG IMPACT,” a book that promises to help you improve your job performance by Monday if you buy it on Friday. Dr. Lewiss and her co-author Dr. Adaira Landry have crafted a wonderful resource packed with practical advice. Dr. Lewiss and Dr. Landry are award-winning physicians,…

[ieatedrawegg]

Lol

[neospacegov]

I Unplugged and saw you And Had a Real Dream for the first time in a long time Last Night…

[indirectas]

Mi mamá me mimaba.

-pasado en presente triste

[neospacegov]

[ID: three drawings of smiling baseballs saying, “What are you gonna do with that big bat? Gonna hit me? Better make it count. Better make it hurt. Better kill me in one shot.” “I crave the cruelty of your bat.” “Smash me you strong motherfucker.” /END ID]

compilation

[eugeniutolici]

#tedm #instagram #fotografia (la Parco Quartiere Baio) https://www.instagram.com/p/CqlXJjEtUhs/?igshid=NGJjMDIxMWI=

[takahashicleaning]

ＴＥＤにて

シーラ・ニーレンバーグ：失明した網膜への新たな補綴治療

（詳しくご覧になりたい場合は上記リンクからどうぞ）

TEDMEDにて、特定の失明状態を抱える患者に対して、視覚回復が、望める大胆なアプローチをシーラ・ニーレンバーグがご紹介します。

補綴装置を視神経に直接つないで、網膜（レティナ；Retina）から、電気信号を脳に送信するという方法です。

網膜は、視覚細胞が面状に並んだ部分で、カメラのレンズのような役割をもつ視覚的な映像を光としてとらえることで、光の情報を神経経由の電気信号に変換する働きを持っている。

この視覚細胞から視神経を通して、脳中枢へと信号を連続的に伝達します。

緑内障なども、網膜神経節細胞に影響が出てくる進行性の病気であり、加齢黄斑変性も、加齢にともなって眼の網膜にある黄斑部が、変性を起こす病気です。

本日、紹介するのは、私たちが研究を続けてきた、より効果的で、失明治療の分岐点になりうる装置です。

その仕組みをお見せします。少し詳しくなりますが、まず、私たちが、解決を目指す課題を理解頂くために、健康な網膜の働きを簡単に説明します。

左側が画像で、次に、網膜 ― 右側が、脳です。

目にこの赤ん坊のような画像が、飛び込んできた際に、網膜最前列の光受容器という視細胞が、これを受け取ります。

さらに、続いて、中心部の網膜回路が作動します。

受信した画像を計算処理し、光情報を抽出して、これをコード(一連の信号)に書き換えます。

この電気パルス信号が、脳に送られます。ここで、画像が最終的には、コード化されるという点が大切になります。

文字通りコード化されます。

画面上のコードは「赤ん坊の顔」を表しており、脳が、この信号配列を受け取ると、脳は、目に映ったものは、赤ん坊の顔だと認識して、異なる信号配列を受信すれば、犬や家といった異なる像を認識します。

大まかには、こんなところです。

実際には、画像は、動的で常に変化しています。

目に映る外界が、常に変るようにパルスの信号配列も常に変化します。まぁ、少し複雑なものなんです。パルスの信号配列は、ミリ秒単位で、目から送信され、脳に何を見ているのかを伝えます。

さて、黄斑変性のような網脈絡膜変性疾患を患った場合には、網膜に何が起こるのでしょう？

最前列の細胞と光受容器が、死滅するだけでなく、繋がっている細胞や網膜回路も全て死滅してしまいます。

最終的に残るのは、脳に情報を送信する出力細胞のみです。

しかし、変性の後は、シグナルを送ることもなくなります。インプットがなくなるので、脳に送信されるはずであった視覚情報が失われます。

これが失明という状態です。

さて、対処法は？というと網膜の光受容器と網膜回路を模倣する装置をつくり、網膜の出力細胞に信号を送り、脳への視覚情報の送信を復旧するというものです。

これが、私たちの研究課題でした。

そして、これがその補綴装置です。

エンコーダとトランスデューサ(変換器)で構成されています。

このエンコーダが、網膜前部の画像の受信とそのコード化のプロセスを代行します。

次に、トランスデューサが、コードを出力細胞へ渡し、脳へコードが送られます。

こうして、この補綴装置は、通常の網膜出力を再現します。

こうすることで網膜回路や光受容器を失った失明状態であっても、脳が、画像と解釈できるように通常通り信号を送れます。

まとめると、本日はコードを介して、脳に正しく伝達できることと、その手段の一例として、私たちの装置を紹介しました。

先ほど申し上げたとおり、データは、他にいくらでもありますので興味のある方にはお見せいたします。

この補綴装置は、運動系装置のように脳からの信号を装置に伝えているわけではありません。外界の情報を脳に伝え、これを脳が理解することが重要なのです。

最後に強調してお伝えしたいのは、この考え方は、汎用的に適用できるという点です。

私たちが、網膜のコードを解明した手順を聴覚や運動系に対応するコード発見に活用することで、聴覚消失症や運動不全障害も治療することが十分可能です。

網膜回路を飛び越えて、その先の出力細胞にたどり着いたのと同じ方法で、蝸牛殻の先の聴覚神経にたどり着いたり、脳卒中によって生じた大脳皮質内と運動皮質との間の溝を埋めることもできます。

こういう新産業でイノベーションが起きるとゲーム理論でいうところのプラスサムになるから既存の産業との

戦争に発展しないため共存関係を構築できるメリットがあります。デフレスパイラルも予防できる？人間の限界を超えてることが前提だけど

しかし、独占禁止法を軽視してるわけではありませんので、既存産業の戦争を避けるため新産業だけの限定で限界を超えてください！

＜おすすめサイト＞

Apple Vision Pro 2024

ニティシュ・パドマナバン:老眼鏡を含めた未来の自動オートフォーカス搭載メガネ

Macでのボイスコントロールが性能アップしてSiriのテクノロジーの向上にともない「一般」 - 「アクセシビリティ」の音声認識も向上しています（Wi-Fi接続は必須）

エリーズ・ロイ：障がい者のためのデザインは全ての人の役に立つ

グレゴリー·ペトスコ：来るべき脳神経疾患の流行における考え

アンドリュー・バストウラウス：次回の目の検査はスマートフォンで

ロン・マッカラム: 私の読書を可能にしたテクノロジー

デニス・ホン：視覚障害者が運転できる車を作る！

ダニエル・キッシュ：音で「見る」ことで、世界を動き回る方法

＜提供＞

東京都北区神谷の高橋クリーニングプレゼント

独自サービス展開中！服の高橋クリーニング店は職人による手仕上げ。お手頃50ですよ。往復送料、曲Song購入可。詳細は、今すぐ電話。東京都内限定。北部、東部、渋谷区周囲。地元周辺区もＯＫです

東京都北区神谷高橋クリーニング店Facebook版

[tedmhindinews]

✨ Happy Dussehra from TEDM NEWS! ✨

हर्षित त्योहार आपके जीवन को खुशियों से भर दे। इस दशहरे, आप सभी को अच्छे स्वास्थ्य और भाग्य का आशीर्वाद मिले। बुराई पर अच्छाई की जीत के इस पावन पर्व पर, खुशी, समृद्धि, और खुशियों की चमक आपके जीवन और आपके घर को रोशन करे।

🎉 आपका जीवन हर दिन नए उत्साह और विजयों से भरा रहे!

Live News Updates @ TEDM NEWS - Hindi News Channel

#HappyDussehra #TEDMNEWS #VictoryOfGoodOverEvil

[neospacegov]

[ID: neospacegov’s character drawn by zhliswp. He leans against the wall and looks to the side at the viewer. He has long, dark hair that falls around his face and covers his one eye. He wears jeans, a gauntlet, and a slanted crop-top that shows off a top surgery scar. Below his eye is a tear drop tattoo. On his bicep is a heart and arrow tattoo. His ear pierced and he wears an inverted cross necklace. He is drawn in a soft, monochrome magenta. Signed Zhōu Lei 01 2023. /END ID]

Can you post kill so I can show him off on my blog like omggg hey look at this beautiful kill commission…

oh yeah here

[danielsiegelalonso]

The Future for Music Accessibility | Daniel Siegel Alonso

Introduction

The integration of live music and festivals in the modern times is yet another vibrant part of our culture today. Beloved music festivals around the world, for instance, Coachella Valley Music and Arts Festival have taken over the modern sphere. Such extremely glamorous affairs in the music industry are not always a source of contentment for all. Inclusivity has been a stagnant issue for a very long time now. Given that oftentimes, the d/Deaf and hard-of-hearing community often gets overlooked at times. The integration of music in our daily lives is more than just beats and harmony.

Going back a couple years ago, compulsive barriers to music accessibility have existed in several forms. For instance, targeting the geographical, financial, physical and technological spheres. As quoted by Petar Kodzas, “TEDm stands for Technology, Entertainment and Design & Music.” — -denoting the futuristic representation of music. Believing that music is as important as anything else in life. Music knows no bounds of beauty when it comes to sharing it with others. Thus, it allows one to enrich themselves through their music enriching others.

Dive Down The Dynamic History of The Music Industry

The Creative interaction of music has been diminishing in the past 20 years or so. Discovering music in today’s time and age through the three lenses of TEDm: Technology, Entertainment and Design & Music can be justifiable.

Technology Unveiled

For evidential reasons, technology has been one of the most important factors contributing to the length of accessibility of music. The number of people having access to music today is larger than it ever was in the past.

Many artists, including Daniel Siegel Alonso, a credible musician who has been in this industry for a long time understands the viability of such situations. Comprehending the depth of making sure that music is accessible for everyone can be ensured by simpler ways of inclusion, for instance:

Providing captions, transcripts, and sign language interpretations in music videos to optimum accessibility.

The development of music can be ensured through making it compatible with the assistive technology.

Designing accessible musical instruments can be the future of music we uphold.

The creation of inclusive music educational programs.

Supporting accessible music communities through thick and thin.

Prime Entertainment

We as individuals celebrating music have evolved since ancient times. We grew out of the tradition where music was part of the ritual and that we all needed to feel the beat. Such is extended with the range of emotions we wish to elaborate and validate through listening to music.

This is best explained in the words of Daniel Siegel Alonso, “Music is about communication. If no one gets it, what’s the point? It’s easy to write something that’s complicated, but the challenge is to write something of substance that people find interesting and accessible.” Oftentimes, the comprehension of music isn’t merely enough for it to be just. The process of engaging with music must allow a plethora of emotions to be felt to form connectivity.

Design

Reasoning with the statement that the influence of technology on dissemination of music is extremely credible. Such an idea that music can be shared with anyone and is accessible regardless of their disabilities ought to be treated normally. Such can refer to both the creation and production aspect of music and the consumption of music.

Music has duality in it, serving two masters, art and design at best. The prime subjects of art have to be aesthetically pleasing and be functional for it to be accessible. Through the conducted research, the involvement of music contributes to the emotional and intellectual development as a child. Thus, music is more about harmonies than just its mere creation.

Conclusion

The future of music isn’t merely dependent on the involvement of more people listening to music, but engaging with it. The well-known accessible mechanisms must be noted while ensuring incorporating new technologies to benefit the audience. Understanding that it is a common misconception that deafness is a disability that hinders the process of comprehending music is crucial to growth.

[neospacegov]

I remember those days giving candy to the insects in the park

[ID: a digital drawing of the artist’s character, C’kay, standing in a park. He has tan skin, colorful pastel clothing and long pink and purple pigtails. Glitter is spread across his cheeks. He looks at the viewer and smiles, holding up a piece of candy. On the ground, ants and a colorful beetle pick at fallen pieces of candy. /END ID]

[vollesroah]

Sex, the vulva and the penis - a few links.

My schooling had almost nothing on anything below the waistline. Sex lessons were almost birds and bees. Zero knowledge transfer of anything beyond there is a vagina and a penis and one day without a user manual (which boys never read) you would somehow create babies together. Neither boys nor girls got anything useful out of the lessons. Knowledge of our bodies cannot be hidden by the prude. I have looked for a few links from ted.com, that should be generally accessible. If you don't know this stuff, learn it and learn about your bodies and those of your partners. And enjoy your bodies.

I’ll start!

1. the clitoris is present in ALL mammal species, as well as many species of birds and reptiles.

2. the clitoris is mostly internal, much larger than you think, and capable of erection. It is made of the exact same tissue types as the penis. It extends from the head of the clitoris (external) all the way to the sides of the vaginal opening (internal), sometimes beyond. it also extends laterally.

3. the full, accurate anatomy of the clitoris is missing from most medical texts. Doctors who perform pelvic surgeries may not know where your clitoral nerves are, and may sever them.

4. most women cannot orgasm without clitoral stimulation, and yet many men expect them to. I suggest these men orgasm without penile stimulation.

5. Indian flying foxes have been observed engaging in cunnilingus, which increases the duration of penetrative sex. Non-human primates have also been observed engaging in cunnilingus.

6. Clitoral stimulation causes ovulation in some mammals for whom the clitoris lies inside the vaginal canal, suggesting an evolutionary function for the clitoris.

7. Some people like to hypothesize that the clitoris is vestigial, despite zero scientific evidence to back this up.

8. The scientific study of the clitoris has been severely impacted by misogyny. Misogyny is also evident in the lack of sex education on the clitoris, where it is often omitted or only discussed briefly.

9. The clitoris has over 10,000 nerve endings.

10. The clitoris is THE source of sexual pleasure and sexual function for 50% of our population.

[fangpunk]

Could you coin a tedm

Paraltive or Paralleltive

An introject who's source is a parallel universe/reality.

(if something similar exists already, please let me know)

Altive/Autive (link)?

if this doesnt fit feel free to send another rq!

[hcsmca]

Massive Science on Lydia Bourouiba

TEDMED is proud to partner with Massive Science, a digital science media publication that brings together scientists and the science-curious public. The team at Massive joined us onsite at TEDMED 2018, and covered talks by various speakers including Lydia Bourouiba. Check out their coverage of Lydia’s TEDMED 2018 talk below.

In 1934, Williams Wells was the first scientist to convincingly describe airborne transmission of diseases in the context of tuberculosis. He introduced the notion of  two main routes of pathogens spread: large droplets, which fall due to gravity, and small droplets, which waft through the air as they evaporate. It is believed that pathogens like Tuberculosis are transmitted through large droplets, whereas diseases like measles could through small ones, although evidence remain controversial and debated. 

It may surprise you that for more than 80 years—despite new diseases, new means of travel, and new technology—our understanding of these basic routes haven’t changed much. Not until recently, when Lydia Bourouiba, associate professor at the Massachusetts Institute of Technology and director of the Fluid Dynamics of Disease Transmission Laboratory, began to revisit these fundamentals and redefine how we think about respiratory disease transmission—literally from the ground up. Bourouiba began her career by studying the mathematics of how fluids flow, specifically looking at fluids with turbulent or chaotic dynamics/motion. When she moved to Toronto shortly after the SARS epidemic, she realized that similar mathematical principles could be useful in modeling how diseases spread. That’s when she began to use mathematics in epidemiology, and in particular, the limitations of top-down modeling with mechanistic understanding of the fundamental mechanisms governing the patterns observed. “I started seeing these gaps in understanding transmission in particular, and [seeing] that fluid dynamics could help fill such gaps,” explains Bourouiba.

Traditionally, scientists have created epidemiological models by developing equations, based on a variety of parameters that describe how diseases are transmitted between people and populations. However, many of these parameters are fitted to data and not based on physical principles—like how sneezing actually transmits disease, or what factors influence how far sneeze droplets may travel or persist. 

Bourouiba thinks that improving the accuracy of these parameters and framework of modeling would greatly improve predictive power and intervention strategies. “If one doesn’t have a mechanism to rationalize [the parameters] down to something we can directly measure, validate, and control, one ends up fitting data to models,” says Bourouiba, rather than designing models that incorporate underlaying physics. “One loses predictability power and ability to control.”

So Bourouiba moved to MIT as an NSERC Postdoctoral Fellow and Applied Mathematics Instructor, and then as faculty, and began to try to explain how diseases are transmitted globally based on how they are transmitted between you and your neighbor. Equipped with a range of experimental optical and biophysics methods, including, direct visualization and measurements, such as with high-speed imaging, microscopy, fluid flow models, and patients, Bourouiba and her team are now answering fundamental questions about the mechanisms of respiratory disease transmission.

During TEDMED, Bourouiba showed how the physics of turbulent puff cloud of air emitted during exhalations, suspending and trapping drops within them, radically  change the range of pathogen deposition and contamination, thus, shifting the paradigm away from the small versus large droplet framework of Wells into the mechanistic description of exhalations including information of time and space, needed for monitoring, infection control and prevention,  and risk assessments. 

The next step is understanding how a exhalations coupled with ambient environment and patient physiology in infection, including when infected with flu, can inform early detection and intervention.  Her broad findings have already identified suggestions for disease control that can be implemented, influencing a variety of public health protocols and policies.

But she still has further questions—like how the size of droplets can impact our susceptibility to disease. “The properties that exhalations and their payload influence also efficacy of infection upon exposure, for example influencing,  their deposition in the lungs,” says Bourouiba. “We are working at elucidating the whole process, accounting for coupled physiology, immunology, microbiology, and fluid processes, to construct the full picture of those  that have particularly high abilities to transmit certain respiratory diseases effectively.”

This could inform how we manage numerous high impact pathogens. Take tuberculosis, a disease that infects up to a third of the world’s population. Researchers know its symptoms begin deep in the lungs, but further characterizations of when, how, and why people produce infectious droplets could improve how we handle patient care and research.

Bourouiba is excited about the multi-year study she’s leading with a diverse collaborations she put in place to  include clinicians, infection control specialists, microbiologists, immunologists, and virologists, for the study of transmission of influenza. Pioneering work in this interdisciplinary field isn’t easy. But Bourouiba says that ten to twenty years of this kind of research could lead to dramatic, tangible results, useful for a variety of pathogens. Considering the long and often uncertain process of developing new vaccines and diagnostics for infectious diseases, her approach to defining evidence-based prevention strategies is a vital piece of the puzzle. “You have to be doing both [prevention and treatment research].” It’s also becoming ever more important. Because of rising antibiotic resistance and increase in connectivity, and emergence and re-emergence of pathogens, she explains, “We might be going into an era [similiar] to pre-antibiotic times, which is extremely concerning.”

Bourouiba’s work is an important step toward redefining disease transmission, and infection control and prevention, moving the fundamentals from descriptions to measurable and quantifiable mechanisms. Truly understanding how people get each other sick will help us design protocols, policies, and tools to help people stay healthy and prevent epidemics and pandemics.

About the author:  Joshua Peters is a PhD student in Biological Engineering at MIT. Around two billion people in the world are infected with a microscopic bug called Mycobacterium Tuberculosis. Despite this, only a fraction develop tuberculosis. And a fraction of those infected – almost 5,000 a day – die. Joshua puts on Stranger Things-esque protection equipment and probes these bacteria to ask, what allows them bacteria to win this tug-of-war? To understand this variation, he looks at how both human and bacteria cells change on a genetic level in response to each other, as a member of the Blainey Lab, located in the Broad Institute, and Bryson Lab, located in the Ragon Institute and MIT.  

The post Massive Science on Lydia Bourouiba appeared first on TEDMED Blog.

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