#Preventing Disease

[happycareclinicnursingservice]

Chronic diseases, such as diabetes, hypertension, and heart disease, require ongoing care and attention. Patients benefit significantly from dedicated healthcare services in Frederick, Maryland. Access to comprehensive care ensures that chronic conditions are managed proactively, reducing complications and improving the quality of life.

[gumjrop]

This year’s flu shot will be missing a strain of influenza it’s protected against for more than a decade.

That’s because there have been no confirmed flu cases caused by the Influenza B/Yamagata lineage since spring 2020. And the Food and Drug Administration decided this year that the strain now poses little to no threat to human health.

Scientists have concluded that widespread physical distancing and masking practiced during the early days of COVID-19 appear to have pushed B/Yamagata into oblivion.

This surprised many who study influenza, as it would be the first documented instance of a virus going extinct due to changes in human behavior, said Dr. Rebecca Wurtz, an infectious disease physician and epidemiologist at the University of Minnesota School of Public Health.

“It is such an interesting and unique story,” Wurtz said, adding that if it were not for COVID, B/Yamagata would still be circulating.

One reason COVID mitigation efforts were so effective at eliminating B/Yamagata is there was already a fair amount of immunity in the population against this strain of flu, which was also circulating at a lower level, said Dr. Kawsar Talaat, an infectious disease physician at Johns Hopkins Bloomberg School of Public Health.

In contrast, SARS-CoV-2 was a brand new virus that no one had encountered before; therefore, masking and isolation only slowed its transmission, but did not stop it.

The absence of B/Yamagata won’t change the experience of getting this year’s flu shot, which the Centers for Disease Control and Prevention recommends to everyone over 6 months old. And unvaccinated people are no less likely to get the flu, as B/Victoria and two influenza A lineages are still circulating widely and making people sick. Talaat said the disappearance of B/Yamagata doesn’t appear to have lessened the overall burden of flu, noting that the level of illness that can be attributed to any strain varies from year to year.

The CDC estimates that between 12,000 and 51,000 people die every year from influenza.

However, the manufacturing process is simplified now that the vaccine is trivalent — designed to protect against three flu viruses — instead of quadrivalent, protecting against four. That change allows more doses to be produced, said Talaat.

Ultimately, the costs of continuing to include protection against B/Yamagata in the flu shot outweigh its benefits, said Talaat.

"If you include a strain for which you don't think anybody's going to get infected into a vaccine, there are some potential risks and no potential benefits," she said. "Even though the risks might be infinitesimal, the benefits are also infinitesimal."

Scientists and public health experts have discussed for the past couple years whether to pull B/Yamagata from the flu vaccine or wait for a possible reemergence, said Kevin R. McCarthy, an assistant professor at the University of Pittsburgh's Center for Vaccine Research. But McCarthy agrees that continuing to vaccinate people against B/Yamagata does not benefit public health.

Additionally, there is a slight chance of B/Yamagata accidentally infecting the workers who manufacture the flu vaccine. The viruses, grown in eggs, are inactivated before being put into the shots: You cannot get influenza from the flu shot. But worker exposure to live B/Yamagata might occur before it's rendered harmless.

That hypothetically could lead to a reintroduction of a virus that populations have waning immunity to because B/Yamagata is no longer making people sick. While that risk is very low, McCarthy said it doesn’t make sense to produce thousands of gallons of a likely extinct virus.

It is possible that B/Yamagata continues to exist in pockets of the world that have less comprehensive flu surveillance. However, scientists aren’t worried that it is hiding in animals because humans are the only host population for B lineage flu viruses.

Scientists determined that B/Yamagata disappeared in a relatively short period of time, and this in and of itself is a success, said McCarthy. That required collaboration and data sharing from people all over the world, including countries that the U.S. has more tenuous diplomatic relationships with, like China and Russia.

“I think the fact that we can do that shows that we can get some things right,” he said.

Sarah Boden is an independent health and science journalist based in Pittsburgh.

[meirimerens]

youtube shorts is just tiktok without being on the app the amount of "i'm a [qualification] and [misinformation]" could make one turn their skin inside-out in protest. "i'm a board-certified OB-GYN & it's only been about the last hundred years that women have actually experienced menopause. We didn't live long enough to experience it" how can you be so incredibly wrong about something so integral to your practice. King of the Hittites Hattusilis III was told in 1250 BCE that his sister was too old to reproduce at age 50+. Aristotle wrote in the 4th century BCE that women stopped menstruating between ages 40 to 50, common menopause ages today still. i cannot begin to tell you how 4th century & 1250 BCE don't really count as "the last hundred years" unless that -s is doing a lot of heavy lifting. waiter waiter more misinformation laws.

[reasonsforhope]

"Since it was first identified in 1983, HIV has infected more than 85 million people and caused some 40 million deaths worldwide.

While medication known as pre-exposure prophylaxis, or PrEP, can significantly reduce the risk of getting HIV, it has to be taken every day to be effective. A vaccine to provide lasting protection has eluded researchers for decades. Now, there may finally be a viable strategy for making one.

An experimental vaccine developed at Duke University triggered an elusive type of broadly neutralizing antibody in a small group of people enrolled in a 2019 clinical trial. The findings were published today [May 17, 2024] in the scientific journal Cell.

“This is one of the most pivotal studies in the HIV vaccine field to date,” says Glenda Gray, an HIV expert and the president and CEO of the South African Medical Research Council, who was not involved in the study.

A few years ago, a team from Scripps Research and the International AIDS Vaccine Initiative (IAVI) showed that it was possible to stimulate the precursor cells needed to make these rare antibodies in people. The Duke study goes a step further to generate these antibodies, albeit at low levels.

“This is a scientific feat and gives the field great hope that one can construct an HIV vaccine regimen that directs the immune response along a path that is required for protection,” Gray says.

-via WIRED, May 17, 2024. Article continues below.

Vaccines work by training the immune system to recognize a virus or other pathogen. They introduce something that looks like the virus—a piece of it, for example, or a weakened version of it—and by doing so, spur the body’s B cells into producing protective antibodies against it. Those antibodies stick around so that when a person later encounters the real virus, the immune system remembers and is poised to attack.

While researchers were able to produce Covid-19 vaccines in a matter of months, creating a vaccine against HIV has proven much more challenging. The problem is the unique nature of the virus. HIV mutates rapidly, meaning it can quickly outmaneuver immune defenses. It also integrates into the human genome within a few days of exposure, hiding out from the immune system.

“Parts of the virus look like our own cells, and we don’t like to make antibodies against our own selves,” says Barton Haynes, director of the Duke Human Vaccine Institute and one of the authors on the paper.

The particular antibodies that researchers are interested in are known as broadly neutralizing antibodies, which can recognize and block different versions of the virus. Because of HIV’s shape-shifting nature, there are two main types of HIV and each has several strains. An effective vaccine will need to target many of them.

Some HIV-infected individuals generate broadly neutralizing antibodies, although it often takes years of living with HIV to do so, Haynes says. Even then, people don’t make enough of them to fight off the virus. These special antibodies are made by unusual B cells that are loaded with mutations they’ve acquired over time in reaction to the virus changing inside the body. “These are weird antibodies,” Haynes says. “The body doesn’t make them easily.”

Haynes and his colleagues aimed to speed up that process in healthy, HIV-negative people. Their vaccine uses synthetic molecules that mimic a part of HIV’s outer coat, or envelope, called the membrane proximal external region. This area remains stable even as the virus mutates. Antibodies against this region can block many circulating strains of HIV.

The trial enrolled 20 healthy participants who were HIV-negative. Of those, 15 people received two of four planned doses of the investigational vaccine, and five received three doses. The trial was halted when one participant experienced an allergic reaction that was not life-threatening. The team found that the reaction was likely due to an additive in the vaccine, which they plan to remove in future testing.

Still, they found that two doses of the vaccine were enough to induce low levels of broadly neutralizing antibodies within a few weeks. Notably, B cells seemed to remain in a state of development to allow them to continue acquiring mutations, so they could evolve along with the virus. Researchers tested the antibodies on HIV samples in the lab and found that they were able to neutralize between 15 and 35 percent of them.

Jeffrey Laurence, a scientific consultant at the Foundation for AIDS Research (amfAR) and a professor of medicine at Weill Cornell Medical College, says the findings represent a step forward, but that challenges remain. “It outlines a path for vaccine development, but there’s a lot of work that needs to be done,” he says.

For one, he says, a vaccine would need to generate antibody levels that are significantly higher and able to neutralize with greater efficacy. He also says a one-dose vaccine would be ideal. “If you’re ever going to have a vaccine that’s helpful to the world, you’re going to need one dose,” he says.

Targeting more regions of the virus envelope could produce a more robust response. Haynes says the next step is designing a vaccine with at least three components, all aimed at distinct regions of the virus. The goal is to guide the B cells to become much stronger neutralizers, Haynes says. “We’re going to move forward and build on what we have learned.”

-via WIRED, May 17, 2024

[watermelinoe]

it's men it's men it's men the problem is men

[juniper-clan]

When did the baby get so wise???

Longpaw??? Great intelligence but what??? /pos

[todaysdocument]

Draft Report [on Tuskegee Syphilis Study]

Record Group 442: Records of the Centers for Disease Control and PreventionSeries: Tuskegee Syphilis Study Administrative Records

-1- 10-8-49.

Alabama Untreated Syphilis Study

[handwritten] "Progression of Abnormalities over 16 yrs"? [/handwritten]

This paper is the fourth of a series of studies of untreated acquired syphilis in the male Negro in Macon County, Alabama. Previous papers [checkmark with "Ref" handwritten above] have health with ["^ (1)" handwritten] the [crossed out] extend of morbidity [/crossed out] ["various abnormalities found" handwritten above] in untreated syphilitics [crossed out] in comparison with [/crossed out] ["and" handwritten above] nonsyphilitic controls, ["at the time of the initial examination" handwritten above] the life expectancy of the respective groups ["after 10 yrs observation." handwritten to the right of the typewritten line] ["^ (2)" handwritten] the natural history of syphilis, uninfluenced by treatment, with special attention to [crossed out] its [/crossed out] ["the" handwritten above] effect ["^of the disease" handwritten above] on the cardiovascular system ["-after 5 yrs observation and" handwritten above]. The present study is a[crossed out "n"] ["^report made after 16 years observation and is an" handwritten above]attempt to estimate the ["- increment of abnormalities" handwritten below] [crossed out] progressive disability [/crossed out] among untreated syphilitics and nonsyphilitic controls ["-recurring during that 16 yr. period" handwritten below] [crossed out] during 16 years of observation. [/crossed out]

How are these different? [handwritten at right side with "HaK" circled below]

The original study population selected during ( the winter [crossed out] seasons [/crossed out] ["months" handwritten above] of) 1931-32 and 1932-33 consisted of 410 syphilitics and 201 ["^controls presumably" handwritten above] nonsyphilitic [crossed out] controls [/crossed out], all of [crossed out] which [/crossed out] ["whom ?" handwritten above] were 25 years of age or ["^older" handwritten above] [illegible text crossed out]. [crossed out] The individuals were carefully selected.[/crossed out] The presence or absence of syphilitic infection was based on personal history, physical examination, and serologic tests on the blood. [crossed out] Before the present far reaching aims of the study were actually set up, 179 [/crossed out] Of the syphilitic group ["^179" handwritten above] were given some treatment for their infection during the

What was the study pop. selected for??? [handwritten at the right with "HaK" circled below]

To be referenced a specific page in this paper. [handwritten at the right, signed "KHZ" below]-2-

period of this first examination. Most of these individuals were among the younger age groups, and were given amounts of treatment varying from 1 to 15 shots of neoarsephenamine. ["-These have been dropped from consideration in the present paper" handwritten above] A second complete physical examination was made of the majority of the group in 1938-39. [crossed out] However, no strenuous effort was made to locate those who received treatment, and consequently a large number of them lapsed from observation. [/crossed out] Since 1939, there has been an annual visit to Macon County by a physician for the purpose of obtaining specimens of blood for serologic examination. In the fall of 1948 a third physical examination was performed on the individuals who could be located at that time, [crossed out] again with no particular emphasis on those who had received some treatment. [/crossed out]

An important phase of the study has been the performance of autopsies on the individuals who have died. Through 1948, [crossed out] 163 [/crossed out] ["140" handwritten above] of the number included in the original population have died, and of these [crossed out] 111 [/crossed out] ["98" handwritten above] have been autopsied. Of those on whom [crossed out] have not been autopsied [/crossed out] ["autopsies have not been performed," handwritten above] proof of death has been established by death certificate or by information furnished by relatives or friends of the deceased. Because of the relatively non-migratory nature of the group, it is reasonably certain that there have been no other deaths than the [crossed out] 163 [/crossed out] ["140" handwritten above] recorded. No analysis of autopsy data will be attempted in this report; a detailed account of this

[cluescorner]

Arlecchino's whole deal is unbelievable

Arlecchino: Huh I wonder what's causing my weird powers? I can't really worry about that right now tho, I've gotta become King and then kill my "Mother".

*Kills Clervie and "Mother"*

Arlecchino: Huh I wonder why I was able to defeat a Fatui Harbinger when I'm like 17 or so? I can't really worry about that right now tho, I've gotta be in jail and become a Harbinger.

*Is in jail for a while and becomes a Harbinger*

Arlecchino: Huh I wonder why I am-

Pierro: Hey what's up hello, anyways you're descended from the Crimson Moon Dynasty of Khaenri'ah. I'm sure that this is a lot for you to take in so-

Arlecchino: Ok.

Pierro: ...You're just cool with that?

Arlecchino: IDK maybe? I can't really worry about that at the moment, I'm a father now. This orphanage full of children I love (who also are child soldiers and are not allowed to leave or else I'll execute them except maybe now I'm just gonna wipe their memories IDK I'm morally complex) isn't gonna run itself.

*Runs the orphanage/spy recruitment initiative*

Me, the fucking player: WHAT DO YOU MEAN YOU ARE KHAENRI'AN? WHY WASN'T THIS BROUGHT UP IN YOUR FUCKING QUEST?? OR ANYTHING ELSE????

Arlecchino, talking to me through my phone: I honestly don't know why you care, I'm too busy to give a shit. Anyways, I'm gonna go fight fate itself I guess. I'm sure that I don't share any thematic parallels with any other Khaenri'an characters (particularly as it relates to acting and family angst) and that I haven't made the idea of 'curses' on Khaenri'ans and what they entail even more complicated than they already were. See ya.

[ricisidro]

The Centers for Disease Control and Prevention (CDC) vaccine advisory group today recommended a second 2024-25 COVID-19 vaccine dose, spaced 6 months apart, for people ages 65 and older and for people in younger age-groups who have moderate or severe immunocompromising conditions.

The group also recommended an extra dose, three or more, in people with immunocompromising conditions.

#SARSCOV2 #COVID19

https://www.cidrap.umn.edu/covid-19/cdc-vaccine-advisers-recommend-second-covid-vaccine-dose-seniors-immune-compromised

[eatclean-bewhole]

[alwaysbewoke]

nice. of course the k-12 education system is underfunded, leading to constant teacher shortages, inadequate facilities, and subpar student outcomes. healthcare access is alarmingly poor, with an unneeded high uninsured rate that leaves many without normal, essential medical services, and even with recent medicaid expansion, mad issues still remain. health outcomes are fckn dismal, with high rates of chronic diseases and preventable deaths. obesity levels are among the worst in the nation (no wonder with all the food insecurity and lack of healthy lifestyle options around there). income inequality is out of control. they got many of their citizens living in poverty with almost zero prospects for improvement. on top of these issues, oklahoma has one of the highest incarceration rates in the country, driven by harsh sentencing laws and systemic failings which targets black and poor (because of course (because america)). all on top of a legacy of racial injustices. i mean the tulsa race massacre. need i say more? but yea they should totally spend 1bil on entertainment. that's a totally reasonable thing to do smfh.

[gumjrop]

Make your voice heard and ask the CDC to:

Recommend COVID vaccines for all ages and health statuses at least twice a year (spring vaccine access for all) AND

Support more frequent updates to the vaccines, adjusted for the latest variants.

Submit a public comment using our sample language below.

The committee is anticipated to vote on the following topic on day 1 of the meeting (October 23): “Use of additional doses of COVID-19 vaccine in immunocompromised individuals and older adults following an initial dose of 2024–2025 vaccine”

Your comments make a difference. At this committee’s June 2024 meeting, public comments from our community led to the committee’s decision to make fall COVID vaccines available to people of all ages, rather than limiting eligibility to specific risk groups. Please join us in making your voice heard for spring COVID vaccine access for all, and at least twice a year access going forward.

Submit Written Comment

You can also register to give Oral Public Comment at the upcoming online CDC ACIP Meeting October 23-24 at: https://www2.cdc.gov/vaccines/acip/acip_publiccomment.asp 

Submit written comments and/or register to make oral comments at the meeting by Friday October 18 at 11:59pm Eastern Standard Time.

It’s important to submit a personalized comment, which can be brief. Ideas for a personalized comment:

How you, your family, or your community would be impacted by spring vaccine eligibility being restricted to only high risk groups (such as older age or immunocompromised status)

Barriers to vaccination your have faced, particularly if your eligibility was questioned or misinterpreted by a vaccine provider

How out-of-pocket costs are a barrier to getting the latest vaccines

Also feel free to take inspiration from or borrow the language in our sample public comment below.

Step-By-Step Submission Instructions:

Step 1. Go to the Regulations.gov to submit your comment.

Step 2. Type in your comment under the field, “Comment.”

Step 3 (optional). Submit a PDF or Word version of your comment under, “Attach Files.”

Step 4. Select either “Individual” or “Anonymous” depending on if you want to share your personal identifiable information that will be publicly available on the Federal Register.

Step 5. If selecting “Individual,” minimally provide your first and last name. If selecting “Anonymous” you can directly submit the comment without sharing your personal identifiable information. Click “Submit Comment.”

Example Comment:

Docket No. CDC-2024-0072-0001 COVID vaccination at least twice a year (at least every six months) must be recommended for people of all ages, regardless of health status. A restrictive approach to eligibility creates undue barriers for vulnerable people and discourages high risk people from getting needed vaccine boosters. People of all ages, including those who are aged 65 and older or immunocompromised, should have the opportunity to receive another COVID vaccine in the spring of 2025. The vaccine schedule should address waning efficacy in the months following vaccination [1-3] as well as emergence of new SARS-CoV-2 strains by recommending updated vaccination for all ages, at least every six months. Waning efficacy is seen with all COVID vaccine types, and recent research into the biological mechanisms of waning [4] supports that this effect occurs regardless of age or immunocompromised status. Recent vaccination is associated with a lower risk of developing Long COVID following a COVID infection [5] as well as a lower risk of Multisystem Inflammatory Syndrome in children (MIS-C) [6].  The CDC’s clear and unequivocal recommendation of COVID vaccination at least twice a year for all ages will influence recommendations by healthcare providers, and coverage by health insurance. Moreover, it will improve public awareness in people of all ages about the importance of recent vaccination (within the last six months) to provide the best protection as part of a multilayered approach to preventing illness. The CDC must ensure equitable and affordable access to updated vaccines and prevent limited access because of financial constraints or demographics. The CDC’s Bridge vaccine access program ended in August 2024 [7], leaving many uninsured and underinsured adults without COVID vaccine access. We ask you to advocate for free COVID vaccine access for all of us to reduce barriers and hesitation to vaccination. References: 1. Link-Gelles R. Effectiveness of COVID-19 (2023-2024 Formula) vaccines. Presented at: FDA VRBPAC Meeting; June 5, 2024. Accessed June 12, 2024. https://www.fda.gov/media/179140/download 2. Wu N, Joyal-Desmarais K, Vieira AM, et al. COVID-19 boosters versus primary series: update to a living review. The Lancet Respiratory Medicine. 2023;11(10):e87-e88. doi:10.1016/S2213-2600(23)00265-5 3. Menegale F, Manica M, Zardini A, et al. Evaluation of Waning of SARS-CoV-2 Vaccine–Induced Immunity: A Systematic Review and Meta-analysis. JAMA Netw Open. 2023;6(5):e2310650. doi:10.1001/jamanetworkopen.2023.10650 4. Nguyen DC, Hentenaar IT, Morrison-Porter A, et al. SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination. Nat Med. Published online September 27, 2024:1-10. doi:10.1038/s41591-024-03278-y 5. Fang Z, Ahrnsbrak R, Rekito A. Evidence Mounts That About 7% of US Adults Have Had Long COVID. JAMA. Published online June 7, 2024. doi:10.1001/jama.2024.11370 6.  Yousaf AR. Notes from the Field: Surveillance for Multisystem Inflammatory Syndrome in Children — United States, 2023. MMWR Morb Mortal Wkly Rep. 2024;73. doi:10.15585/mmwr.mm7310a2 7. https://www.cdc.gov/vaccines/programs/bridge/index.html 

Full instructions for written and oral comment and meeting information can be found at: https://www.cdc.gov/acip/meetings/

You can also register to give Oral Public Comment at the upcoming online CDC ACIP Meeting October 23-24 at: https://www2.cdc.gov/vaccines/acip/acip_publiccomment.asp 

You must register by October 18 at 11:59pm Eastern Standard Time

CDC’s ACIP meeting information on the Federal Register: https://www.federalregister.gov/documents/2024/09/30/2024-22357/meeting-of-the-advisory-committee-on-immunization-practices 

Full Statement:

Vaccination with the latest updated vaccines continues to be foundational to a multilayered approach to COVID, providing protection against both acute disease and Long COVID. Far too few Americans have received the latest vaccines. As of October 11, 2024, only 11.2% of all adults and 26.7% of adults aged 65 and older had received an updated 2024-2025 COVID vaccine. Data for children were unavailable at the time of this writing (October 15, 2024). COVID vaccination rates continue to lag behind influenza vaccination rates. As of July 27, 2024, only 9% of adults aged 65 and older received the recommended two doses of last year’s 2023-2024 vaccine.

Vaccine efficacy wanes significantly four to six months following vaccination, making updated vaccination important for all people as COVID continues to spread in our communities. Vaccine approaches that restrict access based on age or risk status put all of us at risk and leave those at high risk of severe consequences of COVID infection confused about whether they qualify to receive additional doses. These high risk patients may also face barriers as vaccine providers misunderstand the guidelines. A more frequent vaccination approach providing vaccination at least every six months as well as frequent updates to match current variants is needed to better protect all of us amid year-round COVID spread.

Recent vaccination is associated with a lower risk of developing Long COVID following a COVID infection as well as a lower risk of Multisystem Inflammatory Syndrome in children (MIS-C). Waning efficacy is seen with all COVID vaccine types, and recent research into the biological mechanisms of waning supports that this effect occurs regardless of age or immunocompromised status. 

The CDC’s Bridge Access Program, which previously provided COVID vaccines to uninsured and underinsured adults free of charge, ended in August 2024. The end of this program without replacement coverage puts people at risk, and public health officials must advocate for free vaccine access for all of us, including those who are uninsured and underinsured.

Submitted written comments or registration to make oral comments at the meeting must be received by the CDC no later than October 18 at 11:59pm Eastern Standard Time

[stuffbymail]

as a connoisseur of melancholy mid-2000s JRPGs I’m really excited for more people to get to play P3. have an aigis because I love her

[reasonsforhope]

Cancer

“Starting at home, a study last year found that US cancer deaths had declined by 33% since 1991. This is equivalent to around 3.8 million people alive thanks to various efforts to combat the disease family.

The report was authored by the American Cancer Society, and published in the journal CA. American Cancer Society CEO Karen Knudsen called the drop “truly formidable,” while the report attributed the fall to the development of better treatments, the reduction in smoking habits, and earlier detection methods.

Just between 2019 and 2020, cancer death rates dropped 1.5%, while the deployment of the HPV vaccine was correlated with a 65% drop in cervical cancer rates from 2012 through 2019 among women in their 30s.

The report also found that not only are death rates falling, but 5-year survival rates for detected cancers have increased 68% among all diagnoses made between 2012 and 2018.

Guinea Worm Disease

Cancer research often involves cutting edge medical research, but across West Africa and India where cutting edge medicine is not widely available, human determination has succeeded in nearly eradicating Guinea Worm disease.

There are records of this truly unpleasant parasite affecting human health going back thousands of years, and in 1989, there were nearly 1 million cases globally.

But in 2022, this unwelcome waterborne guest created just 15 cases worldwide—a decline of 99.998%, and almost all 15 of those cases occurred in Chad.

This monumental turnaround was not the result of some experimental vaccine, but simple education, teaching people how to avoid drinking contaminated water, when and where this mostly seasonal parasite is likely to be found, and how to treat water to purify it of the Guinea worm.

Ebola

Other than Chad, Guinea Worm disease was also found in Uganda, which produced another medical milestone with the successful eradication of a recent Ebola outbreak.

The outbreak began in September, driven on by the incurable Sudan strain of the virus. It was the worst outbreak in 20 years, but even though there is no vaccine for the Sudan strain, the health authorities managed to contain it to just two administrative districts, and 142 confirmed cases.

“The magic bullet has been our communities who understood the importance of doing what was needed to end the outbreak, and took action,” said health minister Dr. Jane Ruth Aceng Ocero last Wednesday.

Vaccine trials involving Oxford University are currently underway for the Sudan strain, but until that time, health authorities received congratulations for their swift actions, and were thanked for the “lessons learned.””

-via Good News Network, 1/19/23

[g0nta-g0kuhara]

Recently been filling time by trying to think what the best possible course of action would be to prevent Kaito and Kokichi's deaths if I was plopped into v3 right at the beginning of chapter 5

[juniper-clan]

Heronstar's on a banger legacy challenge, 5th generation, grinding for the top-notch infant trait, raising a perfectly ideal family, has never been more girlfailure and Slickclaw just set the camp on fire. also the apprentices are fighting. this is world war 3 but there is a sad woman happy in the middle of it and that is all I need

Heronstar spent three hours and 40 KB downloading hairstyle and clothing mods for all her characters she was BUSY