#Poor Zy xD

[the-friendly-warden]

Zylarath's cub woke up and chose violence xD Zy didn't bring it fungal buds from the nest fast enough because the poor thing had started to doze off... BITE TIME!

[traumalion]

((overbearing & misinformed nuerotypical voice )) "So like, multiple personalities?! What are they like?? Can you control them?? *gasp* can I meet them?!"

((smug nuerotypical voice)) "sweety,, CrA zy people don't knoooow that they're crazy sily goose"

((Obnoxious edgelord nuerotypical voice)) "I'M SOOOOOO PSYCHO TOO XD NORMAL PEOPLE SCARE ME"

((overbearing & condescending nuerotypical voice)) "Oh... :( you must be so troubled... poor thing... the Monsters Within. .. so haunted... you brave soul.... ..."

((rude & arrogant knowitall nuerotypical voice)) "Well that explains _____"

((invasive & rude nuerotypical voice)) "Have you ever been to jail/a psych ward/etc?"

((scared & misinformed nuerotypical voice)) "Uh... are you... on medication? Are you, you know... stable?"

[hourglassstationacademy]

Vanessa may be flirting but she is usually chill enough to notice some people needing rest. So I think they be quite ok.

Also poor Zy, I am sorry. XD

Thanks for these.

Coilean and Zys thoughts about Vanessa if that is ok?

It's always ok <3

Coilean

tall.

She smells like blood. But is not aggressive? Why? Has she found a way to live with the bloodlust..?

She's a little... too laid back for his taste. However, she's also not the worst to be around. As long as she doesn't try to drag him to one of her matches.

(Though sometimes, he wishes he could belong with her group.)

Zy

TOO LOUD.

AAAAAAAAAAAAAAAAAAAAAAAAAA

Zy is! Terrified! Vanessa wishes to TALK! To FLIRT! NO!NONONNONONONONO

Determined to not ever accept anything to drink from her.

[cancersfakianakis1]

Flot2 promotes tumor growth and metastasis through modulating cell cycle and inducing epithelial-mesenchymal transition of hepatocellular carcinoma.

Related Articles

Flot2 promotes tumor growth and metastasis through modulating cell cycle and inducing epithelial-mesenchymal transition of hepatocellular carcinoma.

Am J Cancer Res. 2017;7(5):1068-1083

Authors: Wang CH, Zhu XD, Ma DN, Sun HC, Gao DM, Zhang N, Qin CD, Zhang YY, Ye BG, Cai H, Shi WK, Cao MQ, Tang ZY

Abstract Flotillin-2 (Flot2) is a highly conserved and ubiquitously expressed protein that resides on the cytoplasmic side of the cell membrane within specific cholesterol rich microdomains. Some studies have reported that overexpression of Flot2 is related to cancer progression. However, the role of Flot2 in hepatocellular carcinoma (HCC) remains unclarified. In this study, we aim to explore the correlation between Flot2 expression and HCC progression and the underlying mechanism. In the present study, overexpression of Flot2 in HCC tissues and cell lines was detected, and forced overexpression of Flot2 significantly promoted the proliferation, migration, invasion and metastasis of HCC in vitro and in vivo by modulating cell cycle and inducing EMT, which was mediated via up-regulation of Twist as a result of Raf/MEK/ERK1/2 pathway activation. In contrast, silencing Flot2 expression inhibited these biological processes. Furthermore, high expression of Flot2 was significantly correlated with poor prognosis of HCC patients after curative resection and is an independent risk factor. In conclusion, Flot2 promoted tumor growth and metastasis of HCC through modulating cell cycle and inducing EMT. The expression of Flot2 may play a key role in HCC progression and may be regarded as a potential poor prognostic marker for HCC.

PMID: 28560058 [PubMed]

http://ift.tt/2srPNz5

[the-friendly-warden]

It's ok, Steve! They just want pats!

[the-friendly-warden]

It's now been over a week since poor Zylarath has managed to get any sleep. Their tail is sore from the cub constantly pouncing and biting, their head hurts from the exhaustion and constant screeching. They don't know what to do, so they are just sitting there, holding the little thing by the scruff because at least then it's quiet and not biting!

[cryptid-artha]

Poor Steve, has no idea Zy means no harm xD 10/10 would pat

It's ok, Steve! They just want pats!