#Oligonucleotide Synthesis Market trends

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Oligonucleotide Synthesis Market is Expected to Witness High Growth Owing to Rising Biotechnology Research and Development

The oligonucleotide synthesis market involves the production of shorter sequences of nucleic acids known as oligonucleotides that are widely used in research, diagnostics and therapeutics applications. Oligonucleotides play a vital role in gene expression studies, next-generation sequencing, DNA & RNA analysis, qPCR and molecular diagnostics. The increasing focus on biotechnology research especially in life sciences and genomics has boosted the demand for specialized oligonucleotides.

The Global oligonucleotide synthesis market is estimated to be valued at US$ 4565 Bn in 2024 and is expected to exhibit a CAGR of 13% over the forecast period of 2024 to 2031.

Key Takeaways Key players operating in the oligonucleotide synthesis are Forte Research Systems (India), ICON plc (Ireland), Merge healthcare incorporated (U.S.), Bio-Optronics (U.S.), DSG INC (U.S.), ArisGlobal (India), ERT Clinical Bioclinica (U.S.), Oracle Corporation (U.S.), Medidata Solutions (U.S.), DATATRAK International, Inc. (U.S.), and MedNet Solutions, Inc., (U.S.) among others. These key players are focusing on partnerships and new technology development to expand their oligonucleotide synthesis capabilities.

Key Oligonucleotide Synthesis Market Demand include increasing research in personalized medicine and precision genomics. Additionally, the growing pipeline of oligo-based drugs and clinical trials for rare diseases will provide momentum.

With regards to geographical expansion, North America dominates the global oligonucleotide synthesis market followed by Europe. However, Asia Pacific is expected to witness highest growth rate owing to increasing government support for biotech sector and growing industry investments in China and India.

Market Drivers Increasing R&D expenditure for biotechnology research especially in life sciences and biopharmaceutical industry is a key factor contributing to the Oligonucleotide Synthesis Market Size And Trends Oligonucleotides play a vital role in new drug discovery and development which is propelling many biotech companies to adopt oligo synthesis. Rising applications of oligos in development of advanced therapeutics like antisense oligonucleotides and siRNA is expected to drive the market during the forecast period.

PEST Analysis Political: Government regulations around drug research and development have an impact. Changes in healthcare policies and funding also affect the market. Economic: The state of the economy influences research spending by pharmaceutical companies and academic institutions, affecting demand. Rising healthcare costs drive need for new drug therapies. Social: An aging global population with increased prevalence of diseases like cancer is leading to higher demand for advanced drug development and diagnostic tools. Social attitudes around health and biotech also evolve over time.

Technological: Advancements in DNA sequencing, synthesis and analysis technologies enable new applications and drive down costs, expanding the potential market. Automation and artificial intelligence are enhancing R&D productivity.

North America holds the largest share in terms of value currently due to heavy spending on drug R&D by major players in the US and Canada. However, Asia Pacific is expected to grow at the fastest rate during the forecast period as the pharmaceutical industry expands rapidly in major emerging economies like China and India. These countries are making large investments in research and increasing regulatory approvals are also supporting market growth.

Europe accounts for a sizable share as well owing to extensive government funding for research programs. However, the high costs of oligonucleotide therapies has limited their use thus far. If pricing and reimbursement improve in the future, the European market could witness stronger growth. On the other hand, the Middle East and Africa region is relatively nascent but demand may rise over time with economic development across various nations. Get More Insights On, Oligonucleotide Synthesis Market About Author: Ravina Pandya, Content Writer, has a strong foothold in the market research industry. She specializes in writing well-researched articles from different industries, including food and beverages, information and technology, healthcare, c

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The increasing prevalence of various chronic diseases in the United States like cancer represents one of the primary factors stimulating the market growth. Oligonucleotides are widely used in the development of advanced diagnostic tools, such as liquid biopsy tests and molecular diagnostics for infectious diseases. Additionally, the growing trend of personalized medicine is catalyzing the demand for oligonucleotides for diagnostics and therapies, propelling the market growth. 

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Global Oligonucleotide Synthesis Market Market Size, Share, Trends, Demand, Growth and Competitive Analysis

Oligonucleotide Synthesis Market research report has been prepared with the systematic gathering and evaluation of market information for  industry which is presented in a form that explains various facts and figures to the business. Report saves valuable time as well as adds credibility to the work that is performed to grow business. This quality report has been planned with full commitment and transparency in research and analysis. With the systematic insights of this report, companies can self-assuredly take decisions about the production and marketing strategies. Oligonucleotide Synthesis Market document provides the same by studying the market and the  industry with respect to numerous aspects.

Oligonucleotide Synthesis Market report gives explanation about the different segments of the market analysis which is demanded by today’s businesses. Key players are taking actions such as developments, product launches, acquisitions, mergers, joint ventures and competitive analysis in the  industry. All the market aspects are estimated and analysed by a team of innovative, enthusiastic and motivated researchers and analysts so that nothing lefts uncovered in the report. Global Oligonucleotide Synthesis Market research report, it becomes easy to figure out brand awareness and insight about the brand and product among potential customers.

Oligonucleotide Synthesis Market, By Product (Oligonucleotide, Reagents, and Equipment), Type (Custom Oligos and Predesigned Oligos), Application (Therapeutic Applications, Diagnostics, Research, and Others), End User (Academic Research Institutes, Pharmaceutical and Biotechnology Companies, Diagnostic Laboratories and others) - Industry Trends and Forecast to 2030.

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The report provides insights on the following pointers:

Market Penetration: Comprehensive information on the product portfolios of the top players in the Oligonucleotide Synthesis Market.

Product Development/Innovation: Detailed insights on the upcoming technologies, R&D activities, and product launches in the market.

Competitive Assessment: In-depth assessment of the market strategies, geographic and business segments of the leading players in the market.

Market Development: Comprehensive information about emerging markets. This report analyzes the market for various segments across geographies.

Market Diversification: Exhaustive information about new products, untapped geographies, recent developments, and investments in the Oligonucleotide Synthesis Market.

Global Oligonucleotide Synthesis Market survey report analyses the general market conditions such as product price, profit, capacity, production, supply, demand, and market growth rate which supports businesses on deciding upon several strategies. Furthermore, big sample sizes have been utilized for the data collection in this business report which suits the necessities of small, medium as well as large size of businesses. The report explains the moves of top market players and brands that range from developments, products launches, acquisitions, mergers, joint ventures, trending innovation and business policies.

The following are the regions covered in this report.

North America [U.S., Canada, Mexico]

Europe [Germany, UK, France, Italy, Rest of Europe]

Asia-Pacific [China, India, Japan, South Korea, Southeast Asia, Australia, Rest of Asia Pacific]

South America [Brazil, Argentina, Rest of Latin America]

The Middle East & Africa [GCC, North Africa, South Africa, Rest of the Middle East and Africa]

This study answers to the below key questions:

What are the key factors driving the Oligonucleotide Synthesis Market?

What are the challenges to market growth?

Who are the key players in the Oligonucleotide Synthesis Market?

What are the market opportunities and threats faced by the key players?

Some of the major players operating in the global oligonucleotide synthesis market are:   

Agilent Technologies, Inc. (U.S.)

Atdbio Ltd.(U.K.)

LGC Limited (U.K.)

Bio-Synthesis Inc.(U.S.)

Eurofins Genomics (India),

Kaneka Eurogentec S.A.(Belgium)

General Electric (U.S.)

Genscript (U.S.)

AJINOMOTO CO.,INC (Genedesign, Inc.) (Tokyo)

Danaher (U.S.)

Merck Kgaa (Germany)

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Revenue Forecast and Competitive Landscape for the Oligonucleotide Synthesis Market

The Oligonucleotide Synthesis Market Report for 2024 provides a comprehensive overview of the Oligonucleotide Synthesis Market industry, presenting crucial data and insights into market dynamics, including growth drivers, challenges, and future potential. The report evaluates the Oligonucleotide Synthesis Market Components, focusing on significant opportunities and trends that could shape the industry's trajectory.

According to Straits Research, the global Oligonucleotide Synthesis Market market size was valued at USD 7.74 billion in 2023. It is projected to reach from USD 8.84 billion in 2024 to USD 25.57 billion by 2032, growing at a CAGR of 14.2% during the forecast period (2024–2032).

Get a Sample PDF/Excel of report starting from USD 995 :https://straitsresearch.com/report/oligonucleotide-synthesis-market/request-sample

Top Key Players of Oligonucleotide Synthesis Market :

Agilent Technologies, Inc.

ATDBio Ltd.

TriLink BioTechnologies LLC

Thermo Fisher Scientific

Nitto Denko Corporation

Merck KGaA

LGC Biosearch Technologies

Integrated DNA Technologies, Inc.

GenScript

GE Healthcare

Eurogentec

Eurofins

and more....

Key Insights from the Oligonucleotide Synthesis Market Report

Market Size Overview: The report provides comprehensive estimates of the Oligonucleotide Synthesis Marketsize, including value and sales volume, for the period.

Market Trends and Dynamics: An analysis of the key drivers, opportunities, challenges, and risks shaping the Oligonucleotide Synthesis Market.

Global Economic and Regional Impact: Evaluation of the effects of global inflation and the Russia-Ukraine conflict on the Oligonucleotide Synthesis Market.

Trade Flow Analysis: Detailed examination of import and export volumes of Oligonucleotide Synthesis Marketacross major regions.

Industry Value Chain: Insight into the Oligonucleotide Synthesis Marketvalue chain, covering raw materials, suppliers, manufacturing processes, distributors, and downstream customers.

Industry News, Policies, and Regulations: Coverage of the latest developments, policies, and regulations impacting the Oligonucleotide Synthesis Market.

Regional Analysis for Oligonucleotide Synthesis Market:

The regional analysis section of the report offers a thorough examination of the global Oligonucleotide Synthesis Market market, detailing the sales growth of various regional and country-level markets. It includes precise volume analysis by country and market size analysis by region for both past and future periods. The report provides an in-depth evaluation of the growth trends and other factors impacting the Oligonucleotide Synthesis Market market in key countries, such as the United States, Canada, Mexico, Germany, France, the United Kingdom, Russia, Italy, China, Japan, Korea, India, Southeast Asia, Australia, Brazil, and Saudi Arabia. Moreover, it explores the progress of significant regional markets, including North America, Europe, Asia-Pacific, South America, and the Middle East & Africa.

Oligonucleotide Synthesis Market Segmentations:

By Product Type

Synthesized Oligonucleotide Product

Reagents

Equipment

By Applications

Research

PCR

Sequencing

Gene Synthesis

Diagnostics

Therapeutics

RNAi

Nucleic Acid Aptamers

Others

By End-User

Academic Research Institutes

Pharmaceutical and Biotechnology Companies

Diagnostic Laboratories

Others

Get Detail Market Segmentation :https://straitsresearch.com/report/oligonucleotide-synthesis-market/segmentation

Unit Economics must be known by C-suite professionals:

Cost of Goods Sold (COGS): Includes material, labor, and overhead costs in manufacturing.

R&D Costs: Investment in innovation and compliance with regulations.

Engineering and Design Costs: Resources for design, prototyping, and meeting technical standards.

Production Costs: Specialized manufacturing and quality control expenses.

Supply Chain Costs: Managing procurement and logistics for specialized components.

Testing and Quality Assurance: Costs for ensuring product safety and reliability.

SG&A Costs: Marketing, sales, and administrative expenses.

Revenue per Unit: Income from contracts, services, and licensing.

Gross Margin: Revenue minus COGS, showing unit profitability.

Break-even Analysis: Units or contracts needed to cover total costs.

Customer Acquisition Cost (CAC): Costs to secure new contracts.

Lifetime Value (LTV): Total revenue from a customer over time.

Capital Expenditure (CapEx): Investments in facilities and technology.

Economies of Scale: Cost reductions in larger production runs.

Profit Margin: Final profit after all expenses.

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Support for Informed Decisions: Enhance your decision-making process with in-depth insights into market trends, consumer behavior, and key industry factors. This report is essential for strategic planning, including investments, product development, and marketing strategies.

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COVID-19 Aftermath and Geopolitical Influences: Russia-Ukraine Conflict and Middle East Crisis

The report explores the multifaceted impact of COVID-19 on the Oligonucleotide Synthesis Market market, covering both direct and indirect effects across global and local levels. It discusses market size, trends, and growth trajectories in the Oligonucleotide Synthesis Market , classified by type, application, and customer sector. Additionally, it provides a detailed evaluation of market development components before and after the pandemic, supported by a PESTEL analysis to assess key influencers and barriers to market entry. We offer the flexibility to customize the report based on specific regions, applications, or any other statistical details. Our goal is to align our analysis with your specific needs, ensuring a more complete market study. The final report will also examine the impact of the Russia-Ukraine War on the Oligonucleotide Synthesis Market market, assessing how these geopolitical events are influencing current market conditions and future opportunities.

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Global Peptide And Oligonucleotide CDMO Market Analysis 2024: Size Forecast and Growth Prospects

The peptide and oligonucleotide cdmo global market report 2024from The Business Research Company provides comprehensive market statistics, including global market size, regional shares, competitor market share, detailed segments, trends, and opportunities. This report offers an in-depth analysis of current and future industry scenarios, delivering a complete perspective for thriving in the industrial automation software market.

Peptide And Oligonucleotide CDMO Market, 2024report by The Business Research Company offers comprehensive insights into the current state of the market and highlights future growth opportunities.

Market Size - The peptide and oligonucleotide CDMO market size has grown rapidly in recent years. It will grow from $1.93 billion in 2023 to $2.16 billion in 2024 at a compound annual growth rate (CAGR) of 11.8%. The growth in the historic period can be attributed to a rise in demand for therapeutic agents, advancements in synthesis and manufacturing, personalized medicine trends, regulatory guidelines, and increased focus on antiviral peptides and mRNA vaccines highlighting the potential of oligonucleotides in vaccine development.

The peptide and oligonucleotide CDMO market size is expected to see rapid growth in the next few years. It will grow to $3.39 billion in 2028 at a compound annual growth rate (CAGR) of 12.0%. The growth in the forecast period can be attributed to the growing demand for personalized medicine, advancements in biotechnology, expanding applications, increasing outsourcing, and the growing burden of chronic diseases. Major trends in the forecast period include personalized therapies, technological advancements, quality control challenges, global expansion, and increased collaboration among biopharmaceutical companies.

Order your report now for swift delivery @ https://www.thebusinessresearchcompany.com/report/peptide-and-oligonucleotide-cdmo-global-market-report

Scope Of Peptide And Oligonucleotide CDMO MarketThe Business Research Company's reports encompass a wide range of information, including:

1. Market Size (Historic and Forecast): Analysis of the market's historical performance and projections for future growth.

2. Drivers: Examination of the key factors propelling market growth.

3. Trends: Identification of emerging trends and patterns shaping the market landscape.

4. Key Segments: Breakdown of the market into its primary segments and their respective performance.

5. Focus Regions and Geographies: Insight into the most critical regions and geographical areas influencing the market.

6. Macro Economic Factors: Assessment of broader economic elements impacting the market.

Peptide And Oligonucleotide CDMO Market Overview

Market Drivers -The growing adoption of personalized medicine is expected to propel the growth of the peptide and oligonucleotide CDMO markets going forward. Personalized medicine is an approach to healthcare that tailors medical decisions and treatments to individual characteristics, such as genetics, environment, and lifestyle. The growing adoption of personalized medicine is due to several factors such as advancements in genomic technologies, increased understanding of disease mechanisms at the molecular level, and the demand for more effective and targeted treatment options tailored to individual patients' genetic profiles and medical histories. Peptide and oligonucleotide contract development and manufacturing organizations (CDMOs) play a crucial role in personalized medicine by producing customized therapeutic peptides and oligonucleotides tailored to individual patient needs. For instance, in February 2024, according to the Personalized Medicine Coalition, a UK-based organization promoting the adoption of personalized medicine, the Food and Drug Administration’s (FDA) Center for Drug Evaluation and Research (CDER) approved 16 new personalized treatments for rare disease patients, up from 6 in 2022. Therefore, the growing adoption of personalized medicine is driving the growth of the peptide and oligonucleotide CDMO market.

Market Trends - Major companies operating in the peptide and oligonucleotide CDMO market are focusing on developing strategic partnerships to enhance their service offerings, expand their technological capabilities, and increase their market reach. Peptide development and production partnerships refer to collaborative agreements between two organizations focused on developing and manufacturing peptide-based therapeutics. For instance, in May 2023, PolyPeptide Group AG, a US-based contract development and manufacturing organization (CDMO), partnered with Numaferm GmbH, a Germany-based biotechnology company, for peptide development and production. This partnership aims to utilize PolyPeptide's cGMP manufacturing capacities and market access, along with Numaferm's expertise in sustainable peptide manufacturing and biochemical production platforms. The partnership is focused on jointly exploring the development of suitable peptide candidates with the goal of more sustainable production of peptide-based APIs.

The peptide and oligonucleotide cdmo market covered in this report is segmented –

1) By Product: Peptides, Oligonucleotides 2) By Service Type: Contract Development, Contract Manufacturing, 3) By Application: Therapeutics, Research Applications, Diagnostics, Other Applications 4) By End User: Biopharmaceutical Companies, Pharmaceutical Companies, Research Institutes, Academic and Government Organizations, Others End Users

Get an inside scoop of the peptide and oligonucleotide cdmo market, Request now for Sample Report @ https://www.thebusinessresearchcompany.com/sample.aspx?id=15892&type=smp

Regional Insights - North America was the largest region in the peptide and oligonucleotide CDMO market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the peptide and oligonucleotide cdmo market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

Key Companies - Major companies operating in the peptide and oligonucleotide cdmo market are Thermo Fisher Scientific Inc., Merck KGaA, Ajinomoto Co. Inc., Lonza Group Ag, Wuxi Apptec Co. Ltd., Catalent Inc., Piramal Pharma Ltd, Curia Global Inc., Almac Group, Euroapi SA., CordenPharma International, Bachem Holding AG, Genscript Biotech Corporation, PolyPeptide Group, Rentschler Biopharma SE, Ambiopharm Inc, ScinoPharm, Senn Chemicals AG, Aurigene Pharmaceutical Services, Creative Peptides, Sylentis S.A.

Table of Contents 1. Executive Summary 2. Peptide And Oligonucleotide CDMO Market Report Structure 3. Peptide And Oligonucleotide CDMO Market Trends And Strategies 4. Peptide And Oligonucleotide CDMO Market – Macro Economic Scenario 5. Peptide And Oligonucleotide CDMO Market Size And Growth ….. 27. Peptide And Oligonucleotide CDMO Market Competitor Landscape And Company Profiles 28. Key Mergers And Acquisitions 29. Future Outlook and Potential Analysis 30. Appendix

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New Trends of Oligonucleotide Synthesis Market with Industry Analysis by 2024 – 2030

Oligonucleotide Synthesis Industry Overview

The global oligonucleotide synthesis market size was estimated at USD 3.68 billion in 2023 and is projected to grow at a compound annual growth rate (CAGR) of 13.21% from 2024 to 2030. 

The decreasing prices of sequencing have led to increasing demand for custom-made nucleotides for applications across genetic testing, research, forensics applications, and drug development. This has further boosted the demand for oligonucleotide synthesis. The COVID-19 pandemic has affected every market globally and there has been a surge in the demand for efficient treatment against COVID-19.

Gather more insights about the market drivers, restrains and growth of the Oligonucleotide Synthesis Market

Oligonucleotide therapeutics hold immense potential for treating chronic conditions such as cardiovascular diseases, cancers, and retinal disorders. Emerging new applications of oligo sequences in multiple fields of biotechnology are expected to increase market growth. Demand for molecular diagnostics in precision care is an important emerging application field for oligonucleotide synthesis.

The introduction of advanced techniques such as CRISPR and high-throughput sequencing for gene expression analysis has simplified the genetic screening and modification of genomes. Such innovations are observed to influence the demand for oligonucleotide synthesis. Manufacturers invest in technology development to enable the production of long Oligonucleotides with higher precision and better yield to cater to the growing need for custom oligos.

The availability of a regulatory environment that supports the progress of genomics is the key factor contributing to the market growth. Changes in the regulatory policies to provide a well-framed environment for advanced biological research and application in human use are expected to influence demand for oligonucleotide synthesis significantly. Stem cells, regenerative medicine, genetic engineering, and synthetic biology are the prominent fields identified with high potential in healthcare. For instance, the International Society for Stem Cell Research (ISSCR) ethics and public policy committee aims to recognize and resolve issues by conducting open discussions. The committee includes experts in ethics, law, and social policy worldwide.

Browse through Grand View Research's Biotechnology Industry Research Reports.

The global optical genome mapping market size was valued at USD 104.1 million in 2023 and is expected to grow at a CAGR of 26.76% from 2024 to 2030. 

The global therapeutic drug monitoring market size was valued USD 1.80 billion in 2023 and is projected to grow at a CAGR of 3.8% from 2024 to 2030. 

Key Companies & Market Share Insights

Some of the key players operating in the market include Merck KGaA, Thermo Fisher Scientific, Inc., and Agilent Technologies. These players focus on business strategies such as partnerships/collaborations, product launches, and expansion. Twist Bioscience, Biolegio, and LGC Biosearch Technologies are some of the emerging market participants in the oligonucleotide market. These players primarily focus on expansion and partnerships to strengthen their position in the market.

Key Oligonucleotide Synthesis Companies:

·         Thermo Fisher Scientific, Inc.

·         Merck KGaA

·         Danaher Corporation

·         Dharmacon Inc.

·         Agilent Technologies

·         Bio-synthesis

·         Kaneka Eurogentec S.A

·         LGC Biosearch Technologies

·         Biolegio

·         Twist Bioscience

Recent Developments

In October 2023, IDT inaugurated a new therapeutic manufacturing facility to meet the increasing demand in genomic medicine. The new facility is equipped to support the production of therapeutic oligonucleotides, catering to the expanding needs in the field of genomics and personalized medicine.

In September 2023, Danaher Corporation (Integrated DNA Technologies) introduced a range of xGen NGS products tailored for the Ultima Genomics UG 100TM platform. The suite includes adapters, primers, and universal blockers, catering to various applications such as DNA, RNA, & methylation sequencing workflows. This offering is complemented by IDT's proven hybridization capture chemistry, enhancing versatility for researchers.

In July 2023, Analytix introduced two new instruments designed for organic synthesis, including wavePREP, tailored for oligonucleotide synthesis, and Xelsius, a workstation for multireaction synthesis.

In May 2023, GenScript expanded its life sciences facility in Zhenjiang, Jiangsu, China, to offer a rapid, high-purity oligonucleotide and peptide synthesis service tailored for research & development as well as preclinical applications.

In May 2023, Twist Bioscience and CeGaT GmbH launched the Twist Alliance CeGaT RNA Fusion Panel. This collaborative effort aims to provide a specialized tool for oncology research, facilitating the detection of RNA fusions and enabling transcript variant analysis. RNA fusions, a result of chromosomal arrangements often seen in cancers, can now be efficiently studied using this newly introduced panel.

In February 2023, Fluor Corp. and Agilent Technologies, Inc. collaborated to enhance its oligonucleotide therapeutics manufacturing facility in Frederick, Colorado. Under this collaboration, Fluor is expected to support the project's engineering and procurement. The total value of the project is evaluated at USD 725 million.

Order a free sample PDF of the Oligonucleotide Synthesis Market Intelligence Study, published by Grand View Research.

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Global DNA Encoded Library Market Will Grow At Highest Pace Owing To Rising Demand For Targeted Drug Discovery

DNA encoded library is an innovative approach that employs DNA sequences to encode large chemical libraries for drug discovery. DNA encoded libraries provide advantages like screening of millions of compounds in parallel and facilitating drug discovery research. The technique involves encoding large collections of small molecules, peptides or oligonucleotides with short DNA tags and then screening them for potential hits. This enables high-throughput screens focusing on specific targets for applications in drug discovery, chemical biology and systematic evolution of ligands by exponential enrichment (SELEX).

The Global DNA Encoded Library Market is estimated to be valued at US$ 0.8 Bn in 2024 and is expected to exhibit a CAGR of 16% over the forecast period 2024-2031.

Key Takeaways

Key players operating in the Global DNA Encoded Library are BOC Sciences, DyNAbind, Edelris, GenScript, and HitGen. These players are adopting strategies like collaborations, investments in R&D and new product launches to strengthen their market position. The growing demand for effective therapeutics against various diseases is also boosting the demand for DNA encoded library-based drug discovery worldwide. Additionally, technological advancements like next generation sequencing and mass spectrometry is further enhancing the screening capabilities and fueling the growth of this market.

Market Trends

Some of the key trends driving the growth of the Global DNA Encoded Library market include rising adoption of DNA-encoded library techniques by pharmaceutical companies and growth of clinical trials. The traditional drug discovery methods are being replaced with DNA-encoded techniques owing to their advantages. They enable screening libraries of billions of compounds efficiently in a high-throughput manner. Another trend is the increasing partnerships between technology providers and end-users to accelerate the drug discovery process using DNA-encoded library platforms.

Market Opportunities

The untapped potential of emerging economies and growing research in genomic applications presents huge opportunities for players in this market. Rapid advances in DNA synthesis and sequencing technologies are further expanding the applications of DNA-encoded libraries. Adoption of artificial intelligence and machine learning can also enhance the screening and data analysis capabilities. Development of customized DNA-encoded libraries focused on specific disease pathways will witness high demand in coming years.

Impact Of Covid-19 On Global DNA Encoded Library Market Growth:

The outbreak of Covid-19 pandemic severely impacted the growth of global DNA encoded library market in the initial months of 2020. Various social restrictions imposed by governments like lockdowns and social distancing norms disrupted the supply chain and halted research activities at labs and research institutions globally. This led to delays in drug discovery programs utilizing DNA encoded libraries. Many biopharma companies also shifted resources to focus on Covid-19 vaccine and treatment research in the short term.

However, as research communities and industries adapted to the new normal, activity levels recovered gradually in 2021. The pandemic also highlighted the importance of therapeutics for infectious diseases, boosting investment in areas like antibiotic discovery utilizing DNA encoded libraries. Many players in the market also expedited development of Covid-19 antiviral and treatment libraries. Going forward, market players are focusing on digitalization of operations and remote collaborations to make discovery processes more resilient to future disruptions. Governments are also providing increased funding for genomics and biotech to accelerate development of new drugs.

Concentration Of Global DNA Encoded Library Market In Terms Of Value:

North America region currently accounts for the largest share of global DNA encoded library market in terms of value, estimated at over 40% in 2024. This is due to presence of major pharmaceutical players and contract research organizations (CROs) actively utilizing these libraries for drug discovery programs in the US and Canada. Countries like the US also provide favorable funding environment for genomic and biotech research. Europe is the second largest regional market led by presence of large pharma companies and academic research institutes in countries like UK, Germany and France. The market is also witnessing fastest growth in Asia Pacific region led by China and India. This is attributed to increasing government investments in healthcare sector, emerging biotech industry and growing expertise in DNA sequencing and library construction technologies.

Fastest Growing Region In The Global DNA Encoded Library Market:

Asia Pacific region is poised to emerge as the fastest growing regional market for DNA encoded libraries during the forecast period from 2024 to 2031. This growth can be attributed to increasing government emphasis and funding for research in genomics, biotech and synthetic biology in emerging economies like China and India. Favorable business environment and presence of skilled labor are also attracting many global library developers and pharmaceutical companies to set up research and manufacturing facilities in the region. In addition, the region provides significant cost advantages compared to developed markets for drug discovery processes. With improving standards and widespread adoption of DNA encoded library technologies, Asia Pacific will continue dominating the growth of worldwide market in the coming years.

Get more insights on this topic:   https://www.pressreleasebulletin.com/global-dna-encoded-library-market-set-for-high-growth-due-to-advancements-in-dna-screening-technologies/

Author Bio:

Money Singh is a seasoned content writer with over four years of experience in the market research sector. Her expertise spans various industries, including food and beverages, biotechnology, chemical and materials, defense and aerospace, consumer goods, etc. (https://www.linkedin.com/in/money-singh-590844163 )

What Are The Key Data Covered In This Global DNA Encoded Library Market Report?

:- Market CAGR throughout the predicted period

:- Comprehensive information on the aspects that will drive the Global DNA Encoded Library Market's growth between 2024 and 2031.

:- Accurate calculation of the size of the Global DNA Encoded Library Market and its contribution to the market, with emphasis on the parent market

:- Realistic forecasts of future trends and changes in consumer behaviour

:- Global DNA Encoded Library Market Industry Growth in North America, APAC, Europe, South America, the Middle East, and Africa

:- A complete examination of the market's competitive landscape, as well as extensive information on vendors

:- Detailed examination of the factors that will impede the expansion of Global DNA Encoded Library Market vendors

FAQ’s

Q.1 What are the main factors influencing the Global DNA Encoded Library Market?

Q.2 Which companies are the major sources in this industry?

Q.3 What are the market’s opportunities, risks, and general structure?

Q.4 Which of the top Global DNA Encoded Library Market companies compare in terms of sales, revenue, and prices?

Q.5 Which businesses serve as the Global DNA Encoded Library Market’s distributors, traders, and dealers?

Q.6 How are market types and applications and deals, revenue, and value explored?

Q.7 What does a business area’s assessment of agreements, income, and value implicate?

*Note: 1. Source: Coherent Market Insights, Public sources, Desk research 2. We have leveraged AI tools to mine information and compile it

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Active Pharmaceutical Ingredients Market: Key Companies and Emerging Trends 2024-2030

The global active pharmaceutical ingredients market size was estimated at USD 237.47 billion in 2023 and is expected to grow at a compound annual growth rate (CAGR) of 5.75% from 2024 to 2030. 

Advancements in Active Pharmaceutical Ingredient (API) manufacturing, growth of the biopharmaceutical sector, and an increase in geriatric population are among the key drivers of API market. An increase in prevalence of chronic diseases, such as cardiovascular diseases and cancer, is anticipated to boost market growth.

Global geriatric population is increasing. According to UN, in 2022, people aged 65 and above accounted for 771 million of the population, and the number is anticipated to reach 994 million by 2030 to 1.6 billion by 2050. The number of elderly people is showing fastest growth in Africa, with a threefold increase estimated in people aged 60 and above, followed by Latin America, reaching 18.8 billion by 2050. Aging is considered the greatest risk factor for development of diseases, including cardiovascular and neurological diseases. Thus, rapidly growing global geriatric population is resulting to be a high-impact-rendering driver for API market.

Gather more insights about the market drivers, restrains and growth of the Active Pharmaceutical Ingredients Market

Increasing prevalence of infectious diseases and hospital-acquired infections is driving market growth. In addition, growing incidence of cardiovascular, genetic, and neurologic disorders is anticipated to act as a high-impact-rendering driver for market growth. Cardiovascular Diseases (CVDs) are the most prevalent causes of death globally. According to WHO, cardiovascular diseases cause death of 17.9 million people per day and are expected to cause approximately 25 million deaths by 2030. Increasing epidemiology of lifestyle, aided with rising number of smokers globally, growing incidence of obesity, and increasing dietary irregularities, are factors likely responsible to propel market growth. A recent report by the United Nations (UN) in May 2023 suggests that there has been a 75% increase in the number of girls and 61% in the number of boys with obesity in Europe.

Outsourcing of APIs has become profitable over in-house production. However, this trend took a different turn during the COVID-19 pandemic. Companies are looking to diversify their API suppliers and manufacturers to different locations instead of outsourcing it to just one manufacturer. In addition, risk mitigation is done using dual sourcing to ensure a continuous supply. Hence, key companies aim to capitalize on this ongoing outsourcing trend with new acquisitions. For instance, in August 2023, EUROAPI announced its deal to acquire BianoGMP to enhance its CDMO expertise in oligonucleotide manufacturing, which is a high-growth industry. This further demonstrates the company’s plans for vertical integration.

Browse through Grand View Research's Pharmaceuticals Industry Research Reports.

• The global antipsychotic drugs market size was valued at USD 16.88 billion in 2023 and is projected to grow at a CAGR of 6.1% from 2024 to 2030. 

• The global drug and gene delivery devices market size was valued at USD 670.0 million in 2023 and is projected to grow at a CAGR of 9.0% from 2024 to 2030.

Active Pharmaceutical Ingredients Market Report Segmentation

Grand View Research has segmented the global active pharmaceutical ingredients market report based on type of synthesis, type of manufacturer, type, application, type of drug, and region:

Type of Synthesis Outlook (Revenue, USD Billion, 2018 - 2030)

• Biotech

o Biotech APIs Market, By Type (Revenue, USD Billion, 2018 - 2030)

o Generic APIs

o Innovative APIs

o Biotech APIs Market, By Product (Revenue, USD Billion, 2018 - 2030)

o Monoclonal Antibodies

o Hormones

o Cytokines

o Recombinant Proteins

o Therapeutic Enzymes

o Vaccines

o Blood Factors

• Synthetic

o Synthetic APIs Market, By Type (Revenue, USD Billion, 2018 - 2030)

o Generic APIs

o Innovative APIs

Type of Manufacturer Outlook (Revenue, USD Billion, 2018 - 2030)

• Captive APIs

• Merchant APIs

Type Outlook (Revenue, USD Billion, 2018 - 2030)

• Generic APIs

• Innovative APIs

Application Outlook (Revenue, USD Billion, 2018 - 2030)

• Cardiovascular Diseases

• Oncology

• CNS and Neurology

• Orthopedic

• Endocrinology

• Pulmonology

• Gastroenterology

• Nephrology

• Ophthalmology

• Others

Key Companies & Market Share Insights

Some of the leading players operating in the active pharmaceutical ingredients market include AbbVie, Inc., Novartis AG, Regeneron Pharmaceuticals, Inc., and Eli Lilly and Company. Key players are using existing customer bases in the region to prioritize maintaining high-quality standards and gain high market size access. This marketing strategy is useful for brands that have already built trust in the market. These players are heavily investing in advanced technology and infrastructure, allowing them to efficiently process & analyze a large volume of samples. Moreover, companies undertake various strategic initiatives with other companies and distributors to strengthen their market presence.

Evonik, CARBOGEN AMCIS, and Pharmazell, are some of the emerging market participants in the ophthalmic drugs market. These companies focus on achieving funding support from government bodies and healthcare organizations aided with novel product launches to capitalize on untapped avenues. 

Key Active Pharmaceutical Ingredients Companies:

• Dr. Reddy’s Laboratories Ltd.

• Sun Pharmaceutical Industries Ltd.

• Teva Pharmaceutical Industries Ltd.

• Cipla Inc.

• AbbVie Inc.

• Aurobindo Pharma

• Sandoz International GmbH (Novartis AG)

• Viatris Inc.

• Fresenius Kabi AG

• STADA Arzneimittel AG

Recent Developments

• In August 2023, EUROAPI announced its deal to acquire BianoGMP to enhance its CDMO expertise in oligonucleotide manufacturing, which is a high-growth industry.

• In July 2023, Teva Pharmaceutical Industries Ltd. designed a new strategy for development with potential sale of its API unit on the table. The API manufacturing facility is worth USD 2 billion.

• In June 2023, Lonza acquired Synaffix to improve its ADC services portfolio.

• In April 2023, Eli Lilly announced an investment of USD 1.6 billion in the U.S.-based LEAP Innovation Park. This brings the total investment to USD 3.7 billion to manufacture complex APIs for products such as genetic medicine.

• In February 2023, Lonza completed the manufacturing of its facility in Switzerland. The company enhanced its capacity for its High Potent Active Pharmaceutical Ingredient (HPAPI) manufacturing facility.

• In January 2023, Sterling Pharma Solutions acquired an API manufacturing facility from Novartis in Ringaskiddy, Ireland.

Order a free sample PDF of the Active Pharmaceutical Ingredients Market Intelligence Study, published by Grand View Research. 

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Addressing Challenges in Oligonucleotide Synthesis: Quality, Scale, and Efficiency

The Oligonucleotide Synthesis Market is experiencing rapid growth driven by advancements in genomics, personalized medicine, and molecular diagnostics. Oligonucleotides, short sequences of nucleotides, are essential tools in various applications, including DNA sequencing, gene editing, PCR amplification, and RNA interference. The increasing demand for custom oligonucleotides for research, diagnostic, and therapeutic purposes is fueling the expansion of the oligonucleotide synthesis market.

Get a free Sample: https://www.marketdigits.com/request/sample/4550 

One of the key drivers of market growth is the rising adoption of oligonucleotide-based therapies, such as antisense oligonucleotides (ASOs), siRNAs, and aptamers, for the treatment of genetic disorders, cancer, and infectious diseases. Oligonucleotide therapeutics offer targeted and specific modes of action, allowing for precision medicine approaches and reduced off-target effects compared to traditional small molecule drugs. As a result, pharmaceutical companies and biotech firms are investing heavily in oligonucleotide drug discovery and development, driving the demand for high-quality oligonucleotide synthesis services.

The Oligonucleotide Synthesis Market is Valued USD 8.4 billion in 2024 and projected to reach USD 22.9 billion by 2030, growing at a CAGR of CAGR of 15.5% During the Forecast period of 2024-2032.

In addition to therapeutics, oligonucleotides are widely used in research and diagnostics for studying gene expression, identifying genetic mutations, and detecting infectious agents. The growing demand for personalized medicine and companion diagnostics is driving the need for custom oligonucleotide probes and primers tailored to individual patient profiles. Furthermore, advancements in next-generation sequencing (NGS) technologies and gene editing tools, such as CRISPR-Cas9, are driving the demand for high-throughput oligonucleotide synthesis platforms capable of producing large quantities of oligos with high purity and fidelity.

Major vendors in the global Oligonucleotide Synthesis market are Agilent Technologies, Inc., Biolegio, Biolytic Lab Performance Inc., Bio-Synthesis Inc., Cytiva, DH Life Sciences, LLC., GENERI BIOTECH, Horizon Discovery Ltd., Kaneka Eurogentec S.A, LGC Limited, Maravai LifeSciences, Thermo Fisher Scientific Inc., Twist Bioscience.,  and Others.

The oligonucleotide synthesis market is characterized by the presence of both established players and emerging startups offering a wide range of synthesis platforms and services. Major players in the market include Integrated DNA Technologies, Inc. (IDT), Merck KGaA, Thermo Fisher Scientific Inc., Eurofins Scientific SE, and Bio-Synthesis, Inc., among others. These companies provide custom oligonucleotide synthesis services, as well as a variety of oligo modifications, purification methods, and quality control assays to meet the diverse needs of researchers and clinicians.

Emerging trends in the oligonucleotide synthesis market include the development of novel synthesis chemistries, automation technologies, and digital solutions for designing and ordering custom oligos. Continuous innovation in oligonucleotide synthesis platforms, such as microarray-based synthesis, solid-phase synthesis, and enzymatic synthesis, is driving improvements in oligo yield, length, and quality, enabling new applications in synthetic biology, nanotechnology, and drug delivery.

Looking ahead, the oligonucleotide synthesis market is poised for further expansion driven by advancements in gene therapy, nucleic acid-based vaccines, and precision diagnostics. As the field of genomics continues to evolve, the demand for custom oligonucleotide synthesis services will continue to grow, offering new opportunities for market players to innovate and collaborate in addressing unmet needs in healthcare and life sciences research.

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Peptide And Oligonucleotide CDMO Market Is Expected To Witness Higher Demands Till 2030

The global peptide and oligonucleotide CDMO market is expected to reach USD 5.67 billion by 2030, according to a new report by Grand View Research, Inc. , registering a CAGR of 12.5% from 2024 to 2030. The growing recognition of peptides and oligonucleotides as valuable therapeutic agents for various diseases is fueling the demand for CDMO services. Moreover, the increasing pipeline of peptides and oligonucleotide therapeutics and the growing penetration of CDMOs in the field are a few of the factors driving the growth of the market.

The market is fragmented, with several players having similar technological and processing capabilities. These companies offer various services related to peptide and oligonucleotide development, data interpretation, sample analysis, and clinical trial support. The market is characterized by fierce competition driven by factors such as quality assurance, technological advancements, regulatory compliance, and the ability to offer high-value and diverse services.

The growing investment by major companies in the development and manufacturing of peptides and oligonucleotide-based therapeutics is one of the prominent factors supporting the growth of the market. For instance, in September 2023, CordenPharma announced the expansion of its commercial peptide production capabilities through the enhancement of facilities at CordenPharma Colorado, which now stands as the world's largest Solid-Phase Peptide Synthesis (SPPS) manufacturing facility. Additionally, in September 2023, CombiGene selected AmbioPharm as the CDMO partner for their peptide-based pain project, COZY01, which also involves Zyneyro.

The COVID-19 pandemic moderately impacted the market. The early stages of the COVID-19 pandemic had a notable impact on clinical trials, as a result of travel restrictions, disruptions in the supply chain, and setbacks in clinical trials. Nonetheless, it also presented prospects, notably the heightened emphasis on antiviral peptides and the swift creation of mRNA vaccines. Furthermore, there has been a substantial increase in collaborations and partnerships across biopharmaceutical companies with an aim to boost the production of peptide-based therapeutics.

Peptide And Oligonucleotide CDMO Market Report Highlights

The peptides segment accounted for the largest share of 66.3% in 2023.The segment is driven by the growing demand for peptide-based therapeutics and the rise in the number of clinical trials involving the use of peptides.

Based on the service type, the contract manufacturing segment accounted for the largest share of 65.0% in 2023. The substantial market share in this segment primarily results from the growing demand for outsourced manufacturing services, driven by the cost-effectiveness of outsourced manufacturing.

Biopharmaceutical companies are anticipated to witness the highest CAGR of 13.0% across the analysis timeframe due to the increasing number of biopharmaceutical companies focusing on research and development of peptide-based drugs.

Asia Pacific is anticipated to witness the highest CAGR of 13.4% during the forecast time frame. The substantial growth is primarily attributed to the rising trend of Western pharmaceutical companies outsourcing their manufacturing operations to emerging economies like China and India.

Peptide And Oligonucleotide CDMO Market Segmentation

Grand View Research has segmented the global peptide and oligonucleotide CDMO market based on product, service type, end use, and region:

Peptide And Oligonucleotide CDMO Product Outlook (Revenue, USD Million, 2018 - 2030)

Peptides

Oligonucleotides

Peptide And Oligonucleotide CDMO Service Type Outlook (Revenue, USD Million, 2018 - 2030)

Contract Development

Contract Manufacturing

Peptide And Oligonucleotide CDMO End Use Outlook (Revenue, USD Million, 2018 - 2030)

Pharmaceutical Companies

Biopharmaceutical Companies

Others

Peptide And Oligonucleotide CDMO Regional Outlook (Revenue, USD Million, 2018 - 2030)

North America

U.S.                

Canada

Europe

U.K.

Germany

France

Italy

Spain

Denmark

Sweden

Norway

Asia Pacific

Japan

China

India

Australia

South Korea

Thailand

Latin America

Brazil

Mexico

Argentina

Middle East & Africa

South Africa

Saudi Arabia

UAE

Kuwait

List of Key Players in the Peptide And Oligonucleotide CDMO Market

PolyPeptide Group

STA Pharmaceutical Co. Ltd.

Bachem

Creative Peptides

Aurigene Pharmaceutical Services Ltd.

Merck KGaA

EUROAPI

Curia Global, Inc.

CordenPharm

Sylentis, S.A.