#Oligonucleotide Synthesis Market Industry
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#Oligonucleotide Synthesis Market#Oligonucleotide Synthesis Market Trends#Oligonucleotide Synthesis Market Growth#Oligonucleotide Synthesis Market Industry#Oligonucleotide Synthesis Market Research#Oligonucleotide Synthesis Market Report
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Revenue Forecast and Competitive Landscape for the Oligonucleotide Synthesis Market
The Oligonucleotide Synthesis Market Report for 2024 provides a comprehensive overview of the Oligonucleotide Synthesis Market industry, presenting crucial data and insights into market dynamics, including growth drivers, challenges, and future potential. The report evaluates the Oligonucleotide Synthesis Market Components, focusing on significant opportunities and trends that could shape the industry's trajectory.
According to Straits Research, the global Oligonucleotide Synthesis Market market size was valued at USD 7.74 billion in 2023. It is projected to reach from USD 8.84 billion in 2024 to USD 25.57 billion by 2032, growing at a CAGR of 14.2% during the forecast period (2024–2032).
Get a Sample PDF/Excel of report starting from USD 995 :https://straitsresearch.com/report/oligonucleotide-synthesis-market/request-sample
Top Key Players of Oligonucleotide Synthesis Market :
Agilent Technologies, Inc.
ATDBio Ltd.
TriLink BioTechnologies LLC
Thermo Fisher Scientific
Nitto Denko Corporation
Merck KGaA
LGC Biosearch Technologies
Integrated DNA Technologies, Inc.
GenScript
GE Healthcare
Eurogentec
Eurofins
and more....
Key Insights from the Oligonucleotide Synthesis Market Report
Market Size Overview: The report provides comprehensive estimates of the Oligonucleotide Synthesis Marketsize, including value and sales volume, for the period.
Market Trends and Dynamics: An analysis of the key drivers, opportunities, challenges, and risks shaping the Oligonucleotide Synthesis Market.
Global Economic and Regional Impact: Evaluation of the effects of global inflation and the Russia-Ukraine conflict on the Oligonucleotide Synthesis Market.
Trade Flow Analysis: Detailed examination of import and export volumes of Oligonucleotide Synthesis Marketacross major regions.
Industry Value Chain: Insight into the Oligonucleotide Synthesis Marketvalue chain, covering raw materials, suppliers, manufacturing processes, distributors, and downstream customers.
Industry News, Policies, and Regulations: Coverage of the latest developments, policies, and regulations impacting the Oligonucleotide Synthesis Market.
Regional Analysis for Oligonucleotide Synthesis Market:
The regional analysis section of the report offers a thorough examination of the global Oligonucleotide Synthesis Market market, detailing the sales growth of various regional and country-level markets. It includes precise volume analysis by country and market size analysis by region for both past and future periods. The report provides an in-depth evaluation of the growth trends and other factors impacting the Oligonucleotide Synthesis Market market in key countries, such as the United States, Canada, Mexico, Germany, France, the United Kingdom, Russia, Italy, China, Japan, Korea, India, Southeast Asia, Australia, Brazil, and Saudi Arabia. Moreover, it explores the progress of significant regional markets, including North America, Europe, Asia-Pacific, South America, and the Middle East & Africa.
Oligonucleotide Synthesis Market Segmentations:
By Product Type
Synthesized Oligonucleotide Product
Reagents
Equipment
By Applications
Research
PCR
Sequencing
Gene Synthesis
Diagnostics
Therapeutics
RNAi
Nucleic Acid Aptamers
Others
By End-User
Academic Research Institutes
Pharmaceutical and Biotechnology Companies
Diagnostic Laboratories
Others
Get Detail Market Segmentation :https://straitsresearch.com/report/oligonucleotide-synthesis-market/segmentation
Unit Economics must be known by C-suite professionals:
Cost of Goods Sold (COGS): Includes material, labor, and overhead costs in manufacturing.
R&D Costs: Investment in innovation and compliance with regulations.
Engineering and Design Costs: Resources for design, prototyping, and meeting technical standards.
Production Costs: Specialized manufacturing and quality control expenses.
Supply Chain Costs: Managing procurement and logistics for specialized components.
Testing and Quality Assurance: Costs for ensuring product safety and reliability.
SG&A Costs: Marketing, sales, and administrative expenses.
Revenue per Unit: Income from contracts, services, and licensing.
Gross Margin: Revenue minus COGS, showing unit profitability.
Break-even Analysis: Units or contracts needed to cover total costs.
Customer Acquisition Cost (CAC): Costs to secure new contracts.
Lifetime Value (LTV): Total revenue from a customer over time.
Capital Expenditure (CapEx): Investments in facilities and technology.
Economies of Scale: Cost reductions in larger production runs.
Profit Margin: Final profit after all expenses.
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Support for Informed Decisions: Enhance your decision-making process with in-depth insights into market trends, consumer behavior, and key industry factors. This report is essential for strategic planning, including investments, product development, and marketing strategies.
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COVID-19 Aftermath and Geopolitical Influences: Russia-Ukraine Conflict and Middle East Crisis
The report explores the multifaceted impact of COVID-19 on the Oligonucleotide Synthesis Market market, covering both direct and indirect effects across global and local levels. It discusses market size, trends, and growth trajectories in the Oligonucleotide Synthesis Market , classified by type, application, and customer sector. Additionally, it provides a detailed evaluation of market development components before and after the pandemic, supported by a PESTEL analysis to assess key influencers and barriers to market entry. We offer the flexibility to customize the report based on specific regions, applications, or any other statistical details. Our goal is to align our analysis with your specific needs, ensuring a more complete market study. The final report will also examine the impact of the Russia-Ukraine War on the Oligonucleotide Synthesis Market market, assessing how these geopolitical events are influencing current market conditions and future opportunities.
This Report is available for purchase on :https://straitsresearch.com/buy-now/oligonucleotide-synthesis-market
About Us:
Straits Research is a leading research and intelligence organization, specializing in research, analytics, and advisory services along with providing business insights & research reports.
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#Oligonucleotide Synthesis Market#Oligonucleotide Synthesis Market Share#Oligonucleotide Synthesis Market Size#Oligonucleotide Synthesis Market Research#Oligonucleotide Synthesis Industry#What is Oligonucleotide Synthesis?
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Oligonucleotide Synthesis Market Analysis And Segment Forecast 2024-2030
The global oligonucleotide synthesis market size was estimated at USD 3.68 billion in 2023 and is projected to grow at a compound annual growth rate (CAGR) of 13.21% from 2024 to 2030.
The decreasing prices of sequencing have led to increasing demand for custom-made nucleotides for applications across genetic testing, research, forensics applications, and drug development. This has further boosted the demand for oligonucleotide synthesis. The COVID-19 pandemic has affected every market globally and there has been a surge in the demand for efficient treatment against COVID-19.
Gather more insights about the market drivers, restrains and growth of the Oligonucleotide Synthesis Market
Oligonucleotide therapeutics hold immense potential for treating chronic conditions such as cardiovascular diseases, cancers, and retinal disorders. Emerging new applications of oligo sequences in multiple fields of biotechnology are expected to increase market growth. Demand for molecular diagnostics in precision care is an important emerging application field for oligonucleotide synthesis.
The introduction of advanced techniques such as CRISPR and high-throughput sequencing for gene expression analysis has simplified the genetic screening and modification of genomes. Such innovations are observed to influence the demand for oligonucleotide synthesis. Manufacturers invest in technology development to enable the production of long Oligonucleotides with higher precision and better yield to cater to the growing need for custom oligos.
The availability of a regulatory environment that supports the progress of genomics is the key factor contributing to the market growth. Changes in the regulatory policies to provide a well-framed environment for advanced biological research and application in human use are expected to influence demand for oligonucleotide synthesis significantly. Stem cells, regenerative medicine, genetic engineering, and synthetic biology are the prominent fields identified with high potential in healthcare. For instance, the International Society for Stem Cell Research (ISSCR) ethics and public policy committee aims to recognize and resolve issues by conducting open discussions. The committee includes experts in ethics, law, and social policy worldwide.
Oligonucleotide Synthesis Market Segmentation
Grand View Research has segmented the global oligonucleotide synthesis market report based on product & service, application, and region:
Product & Service Outlook (Revenue, USD Million, 2018 - 2030)
• Oligonucleotides
o DNA
o Column-based
o Array-based
o RNA
o By Technology
o Column-based
o Array-based
o By Type
o Short RNA Oligos (<65 nt)
o Long RNA Oligos (>65 nt)
o CRISPR (sgRNA)
• Equipment/Synthesizer
• Reagents
• Services
o DNA
o Custom Oligo Synthesis Services
o 25 nmol
o 50 nmol
o 200 nmol
o 1000 nmol
o 10000 nmol
o Modification Services
o Purification Services
o RNA
o Custom Oligo Synthesis Services
o 25 nmol
o 100 nmol
o 1000 nmol
o 10000 nmol
o Modification Services
o Purification Services
Application Outlook (Revenue, USD Million, 2018 - 2030)
• PCR Primers
o Academic Research Institutes
o Diagnostic Laboratories
o Pharmaceutical - Biotechnology Companies
• PCR Assays & Panels
o Academic Research Institutes
o Diagnostic Laboratories
o Pharmaceutical - Biotechnology Companies
• Sequencing
o Academic Research Institutes
o Diagnostic Laboratories
o Pharmaceutical - Biotechnology Companies
• DNA Microarrays
o Academic Research Institutes
o Diagnostic Laboratories
o Pharmaceutical - Biotechnology Companies
• Fluorescence In Situ Hybridization (FISH)
o Academic Research Institutes
o Diagnostic Laboratories
o Pharmaceutical - Biotechnology Companies
• Antisense Oligonucleotides
o Academic Research Institutes
o Diagnostic Laboratories
o Pharmaceutical - Biotechnology Companies
• Other Applications
Regional Outlook (Revenue, USD Million, 2018 - 2030)
• North America
o U.S.
o Canada
• Europe
o Germany
o U.K.
o France
o Spain
o Italy
o Denmark
o Sweden
o Norway
• Asia Pacific
o China
o Japan
o India
o South Korea
o Australia
o Thailand
• Latin America
o Brazil
o Mexico
o Argentina
• Middle East and Africa (MEA)
o South Africa
o Saudi Arabia
o UAE
o Kuwait
Browse through Grand View Research's Biotechnology Industry Research Reports.
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Key Companies & Market Share Insights
Some of the key players operating in the market include Merck KGaA, Thermo Fisher Scientific, Inc., and Agilent Technologies. These players focus on business strategies such as partnerships/collaborations, product launches, and expansion. Twist Bioscience, Biolegio, and LGC Biosearch Technologies are some of the emerging market participants in the oligonucleotide market. These players primarily focus on expansion and partnerships to strengthen their position in the market.
Key Oligonucleotide Synthesis Companies:
• Thermo Fisher Scientific, Inc.
• Merck KGaA
• Danaher Corporation
• Dharmacon Inc.
• Agilent Technologies
• Bio-synthesis
• Kaneka Eurogentec S.A
• LGC Biosearch Technologies
• Biolegio
• Twist Bioscience
Recent Developments
• In October 2023, IDT inaugurated a new therapeutic manufacturing facility to meet the increasing demand in genomic medicine. The new facility is equipped to support the production of therapeutic oligonucleotides, catering to the expanding needs in the field of genomics and personalized medicine.
• In September 2023, Danaher Corporation (Integrated DNA Technologies) introduced a range of xGen NGS products tailored for the Ultima Genomics UG 100TM platform. The suite includes adapters, primers, and universal blockers, catering to various applications such as DNA, RNA, & methylation sequencing workflows. This offering is complemented by IDT's proven hybridization capture chemistry, enhancing versatility for researchers.
• In July 2023, Analytix introduced two new instruments designed for organic synthesis, including wavePREP, tailored for oligonucleotide synthesis, and Xelsius, a workstation for multireaction synthesis.
• In May 2023, GenScript expanded its life sciences facility in Zhenjiang, Jiangsu, China, to offer a rapid, high-purity oligonucleotide and peptide synthesis service tailored for research & development as well as preclinical applications.
• In May 2023, Twist Bioscience and CeGaT GmbH launched the Twist Alliance CeGaT RNA Fusion Panel. This collaborative effort aims to provide a specialized tool for oncology research, facilitating the detection of RNA fusions and enabling transcript variant analysis. RNA fusions, a result of chromosomal arrangements often seen in cancers, can now be efficiently studied using this newly introduced panel.
• In February 2023, Fluor Corp. and Agilent Technologies, Inc. collaborated to enhance its oligonucleotide therapeutics manufacturing facility in Frederick, Colorado. Under this collaboration, Fluor is expected to support the project's engineering and procurement. The total value of the project is evaluated at USD 725 million.
Order a free sample PDF of the Oligonucleotide Synthesis Market Intelligence Study, published by Grand View Research.
#Oligonucleotide Synthesis Market#Oligonucleotide Synthesis Industry#Oligonucleotide Synthesis Market size#Oligonucleotide Synthesis Market share#Oligonucleotide Synthesis Market analysis
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The Phosphoramidite Industry: Trends, Growth, and Market Insights
Market Overview:
The global phosphoramidite market is expected to grow at a compound annual growth rate (CAGR) of 6-8% from 2023 to 2028. Phosphoramidites play a pivotal role in the synthesis of oligonucleotides, which are fundamental in genetic research, diagnostics, and the development of RNA and DNA-based drugs. As the demand for genetic therapies, personalized medicine, and molecular diagnostics rises, the phosphoramidite industry is experiencing substantial growth.
Phosphoramidites are used to introduce specific nucleotides into DNA and RNA sequences during oligonucleotide synthesis. The ability to control this synthesis process with high precision makes phosphoramidites essential for various applications, including PCR (Polymerase Chain Reaction), gene sequencing, gene editing (like CRISPR), and the development of antisense therapies.
Key Market Trends:
Growing Demand for Nucleic Acid-Based Therapies: One of the main drivers of the phosphoramidite market is the increasing development and approval of nucleic acid-based therapies such as antisense oligonucleotides (ASOs), siRNA (small interfering RNA), and mRNA-based vaccines. These therapies are being developed to target various genetic diseases and cancers, with the potential to revolutionize treatments for conditions that are difficult to address with traditional drugs. As a result, there is growing demand for phosphoramidites to synthesize the oligonucleotides used in these therapies.
Advancements in Biotechnology and Genetic Research: The rise of biotechnology and genetic research is a key factor contributing to the growth of the phosphoramidite market. With the increasing use of genetic sequencing, gene synthesis, and CRISPR gene editing technologies, the need for high-quality phosphoramidites in the synthesis of oligonucleotides is on the rise. As these technologies continue to evolve and become more accessible, the demand for phosphoramidites is expected to grow significantly in both research and commercial applications.
Molecular Diagnostics and Personalized Medicine: Molecular diagnostics is another area driving the demand for phosphoramidites. The use of oligonucleotides in the detection of genetic mutations, pathogens, and biomarkers is becoming increasingly important in clinical diagnostics. Personalized medicine, which tailors medical treatment to the individual characteristics of each patient, also depends on the ability to design specific DNA or RNA sequences for targeted therapies. Phosphoramidites are vital in synthesizing the oligonucleotides required for these applications, further boosting market growth.
Increasing Applications in Gene Editing: Gene editing technologies like CRISPR-Cas9 have gained immense popularity for their ability to precisely edit genes in various organisms, including humans. These technologies often rely on oligonucleotides synthesized using phosphoramidites to guide the gene-editing machinery to specific locations in the genome. The rising demand for gene-editing applications in both research and therapeutics is driving the phosphoramidite market, as these oligonucleotides are essential for the success of CRISPR-based applications.
Technological Advancements in Oligonucleotide Synthesis: As the demand for precision and scalability in oligonucleotide synthesis grows, advancements in synthesis technologies are emerging. New methods that increase the efficiency, purity, and yield of oligonucleotide synthesis are driving further growth in the phosphoramidite market. The introduction of automated synthesis platforms, as well as improvements in phosphoramidite production processes, are making it easier to meet the rising demand for high-quality oligonucleotides.
Increasing Investment in Pharmaceutical R&D: The growing investment in pharmaceutical and biotechnology research and development (R&D) activities is driving demand for phosphoramidites. Pharmaceutical companies and academic research institutions are heavily investing in RNA-based therapeutics and gene therapies, which require the synthesis of custom oligonucleotides. As these R&D activities increase, the demand for phosphoramidites used in the synthesis of these specialized nucleic acids is also expected to rise.
Market Segmentation:
The phosphoramidite market can be segmented based on application, end-user, and region.
By Application:
Oligonucleotide Synthesis: The primary application of phosphoramidites, as they are used to build custom DNA and RNA sequences for various research and therapeutic purposes.
Gene Editing and CRISPR Technologies: Phosphoramidites are crucial for the synthesis of oligonucleotides used in gene-editing processes, including CRISPR.
RNA Therapeutics: The development of RNA-based therapies, such as RNA vaccines, antisense oligonucleotides, and siRNA, is a major application for phosphoramidites.
Diagnostics: Used in molecular diagnostic applications, including PCR, gene sequencing, and the detection of genetic disorders or pathogens.
By End-User:
Pharmaceutical and Biotechnology Companies: The largest segment, where phosphoramidites are used for the synthesis of therapeutic oligonucleotides, including antisense oligonucleotides and gene therapies.
Academic and Research Institutions: Universities and research labs are key users of phosphoramidites for genetic research, gene synthesis, and drug discovery.
Diagnostic Laboratories: Laboratories that perform genetic testing and molecular diagnostics are significant consumers of phosphoramidites.
By Region:
North America: Home to leading pharmaceutical and biotechnology companies, North America holds a substantial share of the global phosphoramidite market. The region’s strong emphasis on drug development, gene therapy, and personalized medicine is expected to drive significant demand.
Europe: Europe is another major market for phosphoramidites, driven by advanced research in genomics and biotechnology, as well as increasing demand for molecular diagnostics.
Asia-Pacific: With its rapidly expanding pharmaceutical and biotech sectors, the Asia-Pacific region is witnessing an increase in the demand for phosphoramidites, particularly in China and India.
Rest of the World: Emerging markets in Latin America, the Middle East, and Africa are also growing, although at a slower pace.
Growth Drivers:
Rising Demand for Genetic Therapies and mRNA Vaccines: The COVID-19 pandemic highlighted the importance of mRNA vaccines, and the success of these vaccines has sparked increased interest in mRNA technology for other infectious diseases and even cancer treatments. The ongoing research and development in this space are driving the need for high-quality phosphoramidites for RNA synthesis.
Advancements in Biotechnology and Genetic Research: Continuous innovation in biotechnology, including gene editing and genetic testing, is increasing the need for phosphoramidites. As more industries adopt genetic-based technologies, the demand for reliable and efficient oligonucleotide synthesis will continue to rise.
Government and Private Sector Investments in Biotechnology: Governments and private companies are investing heavily in biotechnology R&D, particularly in the fields of genomics and gene therapy. This investment is creating a strong demand for phosphoramidites, which are essential for these innovative therapeutic approaches.
Personalized Medicine and Precision Healthcare: The rise of personalized medicine, which tailors treatment to an individual’s genetic makeup, is also contributing to the growth of the phosphoramidite market. Oligonucleotides are key tools in the development of personalized medicine, making phosphoramidites a vital component of this emerging healthcare trend.
Challenges Facing the Market:
High Production Costs: The production of phosphoramidites is a complex and costly process. High production costs could limit the widespread adoption of these chemicals in some applications, especially in price-sensitive markets. Companies may face challenges in reducing these costs while maintaining product quality.
Quality Control and Standardization: As the demand for high-quality phosphoramidites increases, maintaining consistent product quality and meeting regulatory standards will be essential. Manufacturers must invest in robust quality control systems to ensure the purity and effectiveness of phosphoramidites used in critical applications like gene therapy and diagnostics.
Intellectual Property and Patent Issues: The increasing focus on nucleic acid-based therapies and gene-editing technologies has led to an increase in intellectual property (IP) concerns and patent disputes. Companies involved in phosphoramidite production may face challenges related to IP rights and patent licensing in the rapidly evolving biotech and pharmaceutical sectors.
Key Players in the Phosphoramidite Market:
Sigma-Aldrich (Merck): A leading supplier of phosphoramidites, with a broad portfolio catering to the synthesis of oligonucleotides and RNA-based therapies.
GE Healthcare Life Sciences: Known for its contributions to molecular diagnostics and gene synthesis, GE Healthcare is a key player in the phosphoramidite market.
BioAutomation Corporation: Specializes in the development of automated oligonucleotide synthesis systems, playing a crucial role in the phosphoramidite supply chain.
Trilink BioTechnologies: A prominent supplier of custom phosphoramidites for DNA and RNA synthesis, including modifications for therapeutic applications.
Fisher Scientific: A global distributor of chemicals, including phosphoramidites, for research and therapeutic applications in the life sciences.
Market Outlook:
The phosphoramidite market is poised for significant growth in the coming years, driven by advancements in biotechnology, personalized medicine, and the increasing adoption of genetic-based therapies. With applications ranging from gene editing and molecular diagnostics to RNA therapeutics, phosphoramidites are essential for the continued innovation in genetic research and therapeutic development. Although challenges such as high production costs and quality control remain, the overall market outlook is optimistic, with substantial opportunities for growth, especially in North America and Europe.
As demand for more precise, targeted therapies and diagnostics continues to rise, the phosphoramidite industry will play an integral role in shaping the future of biotechnology, drug development, and personalized healthcare.
For a detailed overview and more insights, you can refer to the full market research report by Mordor Intelligence
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DNA Synthesis Market 2030: Brief Analysis of Top Countries Data, Growth and Drivers
The global DNA synthesis market was valued at USD 3.13 billion in 2023 and is expected to grow at a compound annual growth rate (CAGR) of 15.30% from 2024 to 2030. This growth can largely be attributed to the increasing demand for DNA synthesis driven by its applications in several fields, including molecular biology, genetic engineering, and clinical diagnostics and therapeutics. Additionally, the rising need for research in drug discovery and personalized medicine is expected to further boost market expansion during the forecast period.
The market is also seeing moderate merger and acquisition activity, driven by factors such as the desire to enhance competitive positioning within the industry and the need for consolidation in a rapidly growing market. Companies are increasingly entering into collaborations to support advancements in research and development (R&D) in diagnostics and therapeutics. For example, in April 2023, Twist Bioscience, a leader in the DNA synthesis market, announced a collaboration with Astellas Pharma to assist in antibody discovery for immunotherapies. These strategic alliances are expected to strengthen the market's growth trajectory as they enhance innovation in gene-related research.
Gather more insights about the market drivers, restrains and growth of the DNA Synthesis Market
Regional Insights:
North America DNA Synthesis Market Trends
North America held the largest market share, accounting for 39.76% of the global revenue in 2023. The region’s growth is driven by heightened public awareness about genetic disorders, along with robust medical facilities and substantial investments in research and development. The prevalence of chronic illnesses, such as cancer, diabetes, and cardiovascular diseases, further amplifies the demand for DNA synthesis as a tool for understanding and treating these conditions. Additionally, North American market players are heavily investing in gene synthesis and gene therapy research, creating a fertile environment for growth. The presence of leading DNA synthesis companies in the region, along with continuous advancements in gene editing technologies, further supports regional expansion.
U.S.
The U.S. DNA synthesis market has been experiencing significant growth, largely driven by the increasing demand for synthetic DNA and RNA sequences for various applications. These include molecular research, diagnostics, and therapeutics. The market's competitive landscape is diverse, consisting of both established players and emerging companies that are eager to secure a share of this expanding market. The U.S. market is particularly influenced by advancements in personalized medicine and genetic therapies, which heavily rely on DNA synthesis for drug development, disease prevention, and treatment personalization.
Asia Pacific DNA Synthesis Market Trends
The DNA synthesis market in the Asia Pacific region is anticipated to grow at the fastest rate, with a CAGR of 17.50% from 2024 to 2030. This growth is attributed to the increasing demand for synthetic DNA in research, diagnostics, and therapeutics, along with the rising prevalence of genetic diseases and the growing need for personalized medicine.
China
China is expected to experience the highest growth rate in the DNA synthesis market, with a projected CAGR of 21.41%. Factors contributing to this growth include the rising number of contract research organizations (CROs) and the outsourcing of drug discovery and development activities by pharmaceutical and biotech companies. Additionally, China’s focus on expanding and upgrading its gene synthesis facilities is further accelerating market growth. For example, in May 2023, GenScript expanded its oligonucleotide manufacturing facility in Jiangsu, China, to enhance its production capacity.
Japan
Japan is also expected to witness significant growth due to its aging population and emphasis on personalized medicine. As a leader in scientific research, especially in biotechnology and biopharmaceuticals, Japan has a strong focus on genetic studies and gene expression profiling, which are crucial to the DNA synthesis market. These factors are expected to further drive the demand for DNA synthesis in the region.
India
The DNA synthesis market in India is anticipated to grow rapidly due to the country’s high birth rate and the significant prevalence of genetic disorders, exacerbated by factors like consanguineous marriages and founder mutations. Government initiatives, such as the "Make in India" program and biotechnology R&D grants, are empowering domestic players and attracting foreign investments. Notably, the Department of Biotechnology (DBT) launched the UMMID initiative in 2019 to address inherited genetic diseases in newborns, further stimulating the DNA synthesis market.
Europe DNA Synthesis Market Trends
Europe represents another key region in the DNA synthesis market. This is largely due to strong government support, continuous advancements in research infrastructure, and an increasing prevalence of chronic diseases like cancer, cardiovascular conditions, and genetic disorders. The growing adoption of gene therapy is also contributing to the market's growth.
UK
The DNA synthesis market in the UK is poised for growth, driven by ongoing research and innovation in genetics and molecular studies. Government initiatives and strong healthcare infrastructure provide a conducive environment for biomedical research. For instance, in November 2023, the UK's approval of the CRISPR-based gene-editing therapy Casgevy marked a significant milestone, positioning the UK DNA synthesis market for further growth.
France
France faces a significant burden from cancer, which remains a leading cause of death in the country. The demand for DNA synthesis in France is driven by its growing role in cancer diagnostics and personalized medicine, particularly through gene expression profiling and liquid biopsies. Furthermore, cardiovascular diseases, such as atherosclerosis and heart failure, are contributing to the growing interest in oligonucleotides and genetic profiles for both diagnostic and therapeutic purposes, pushing the demand for DNA synthesis technologies.
Germany
Germany’s DNA synthesis market is expected to grow due to the country’s strong R&D focus in diagnostics and therapeutics. Germany is actively promoting biotechnology and healthcare infrastructure through initiatives like “Industrie 4.0” and providing grants for R&D. These efforts not only boost the domestic market but also attract foreign investment, further driving the DNA synthesis market in Germany.
Browse through Grand View Research's Category Biotechnology Industry Research Reports.
The global exosomes market size was estimated at USD 177.4 million in 2024 and is anticipated to grow at a CAGR of 28.73% from 2025 to 2030.
The global cell culture media storage containers market size was estimated at USD 2.11 billion in 2024 and is projected to witness a CAGR of 12.55% from 2025 to 2030.
Key DNA Synthesis Companies:
Thermo Fisher Scientific, Inc
Twist Bioscience
BIONEER CORPORATION
Eton Bioscience, Inc.
LGC Biosearch Technologies
IBA Lifesciences GmbH
Eurofins Scientific
Integrated DNA Technologies, Inc.
Quintara Biosciences
GenScript
Order a free sample PDF of the DNA Synthesis Market Intelligence Study, published by Grand View Research.
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DNA Synthesis Market Research Report 2030 By Players, Regions, Types & Applications
The global DNA synthesis market was valued at USD 3.13 billion in 2023 and is expected to grow at a compound annual growth rate (CAGR) of 15.30% from 2024 to 2030. This growth can largely be attributed to the increasing demand for DNA synthesis driven by its applications in several fields, including molecular biology, genetic engineering, and clinical diagnostics and therapeutics. Additionally, the rising need for research in drug discovery and personalized medicine is expected to further boost market expansion during the forecast period.
The market is also seeing moderate merger and acquisition activity, driven by factors such as the desire to enhance competitive positioning within the industry and the need for consolidation in a rapidly growing market. Companies are increasingly entering into collaborations to support advancements in research and development (R&D) in diagnostics and therapeutics. For example, in April 2023, Twist Bioscience, a leader in the DNA synthesis market, announced a collaboration with Astellas Pharma to assist in antibody discovery for immunotherapies. These strategic alliances are expected to strengthen the market's growth trajectory as they enhance innovation in gene-related research.
Gather more insights about the market drivers, restrains and growth of the DNA Synthesis Market
Regional Insights:
North America DNA Synthesis Market Trends
North America held the largest market share, accounting for 39.76% of the global revenue in 2023. The region’s growth is driven by heightened public awareness about genetic disorders, along with robust medical facilities and substantial investments in research and development. The prevalence of chronic illnesses, such as cancer, diabetes, and cardiovascular diseases, further amplifies the demand for DNA synthesis as a tool for understanding and treating these conditions. Additionally, North American market players are heavily investing in gene synthesis and gene therapy research, creating a fertile environment for growth. The presence of leading DNA synthesis companies in the region, along with continuous advancements in gene editing technologies, further supports regional expansion.
U.S.
The U.S. DNA synthesis market has been experiencing significant growth, largely driven by the increasing demand for synthetic DNA and RNA sequences for various applications. These include molecular research, diagnostics, and therapeutics. The market's competitive landscape is diverse, consisting of both established players and emerging companies that are eager to secure a share of this expanding market. The U.S. market is particularly influenced by advancements in personalized medicine and genetic therapies, which heavily rely on DNA synthesis for drug development, disease prevention, and treatment personalization.
Asia Pacific DNA Synthesis Market Trends
The DNA synthesis market in the Asia Pacific region is anticipated to grow at the fastest rate, with a CAGR of 17.50% from 2024 to 2030. This growth is attributed to the increasing demand for synthetic DNA in research, diagnostics, and therapeutics, along with the rising prevalence of genetic diseases and the growing need for personalized medicine.
China
China is expected to experience the highest growth rate in the DNA synthesis market, with a projected CAGR of 21.41%. Factors contributing to this growth include the rising number of contract research organizations (CROs) and the outsourcing of drug discovery and development activities by pharmaceutical and biotech companies. Additionally, China’s focus on expanding and upgrading its gene synthesis facilities is further accelerating market growth. For example, in May 2023, GenScript expanded its oligonucleotide manufacturing facility in Jiangsu, China, to enhance its production capacity.
Japan
Japan is also expected to witness significant growth due to its aging population and emphasis on personalized medicine. As a leader in scientific research, especially in biotechnology and biopharmaceuticals, Japan has a strong focus on genetic studies and gene expression profiling, which are crucial to the DNA synthesis market. These factors are expected to further drive the demand for DNA synthesis in the region.
India
The DNA synthesis market in India is anticipated to grow rapidly due to the country’s high birth rate and the significant prevalence of genetic disorders, exacerbated by factors like consanguineous marriages and founder mutations. Government initiatives, such as the "Make in India" program and biotechnology R&D grants, are empowering domestic players and attracting foreign investments. Notably, the Department of Biotechnology (DBT) launched the UMMID initiative in 2019 to address inherited genetic diseases in newborns, further stimulating the DNA synthesis market.
Europe DNA Synthesis Market Trends
Europe represents another key region in the DNA synthesis market. This is largely due to strong government support, continuous advancements in research infrastructure, and an increasing prevalence of chronic diseases like cancer, cardiovascular conditions, and genetic disorders. The growing adoption of gene therapy is also contributing to the market's growth.
UK
The DNA synthesis market in the UK is poised for growth, driven by ongoing research and innovation in genetics and molecular studies. Government initiatives and strong healthcare infrastructure provide a conducive environment for biomedical research. For instance, in November 2023, the UK's approval of the CRISPR-based gene-editing therapy Casgevy marked a significant milestone, positioning the UK DNA synthesis market for further growth.
France
France faces a significant burden from cancer, which remains a leading cause of death in the country. The demand for DNA synthesis in France is driven by its growing role in cancer diagnostics and personalized medicine, particularly through gene expression profiling and liquid biopsies. Furthermore, cardiovascular diseases, such as atherosclerosis and heart failure, are contributing to the growing interest in oligonucleotides and genetic profiles for both diagnostic and therapeutic purposes, pushing the demand for DNA synthesis technologies.
Germany
Germany’s DNA synthesis market is expected to grow due to the country’s strong R&D focus in diagnostics and therapeutics. Germany is actively promoting biotechnology and healthcare infrastructure through initiatives like “Industrie 4.0” and providing grants for R&D. These efforts not only boost the domestic market but also attract foreign investment, further driving the DNA synthesis market in Germany.
Browse through Grand View Research's Category Biotechnology Industry Research Reports.
The global exosomes market size was estimated at USD 177.4 million in 2024 and is anticipated to grow at a CAGR of 28.73% from 2025 to 2030.
The global cell culture media storage containers market size was estimated at USD 2.11 billion in 2024 and is projected to witness a CAGR of 12.55% from 2025 to 2030.
Key DNA Synthesis Companies:
Thermo Fisher Scientific, Inc
Twist Bioscience
BIONEER CORPORATION
Eton Bioscience, Inc.
LGC Biosearch Technologies
IBA Lifesciences GmbH
Eurofins Scientific
Integrated DNA Technologies, Inc.
Quintara Biosciences
GenScript
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What Is DNA Oligo Synthesis and Why Is It Important in Research?
DNA Oligo Synthesis is a laboratory technique of synthesis of small segments of DNA molecules known as oligonucleotides. These synthetic strands are important instruments for scientists working on matter the genetic makeup, molecular biology and new medications. The ability to design and produce these DNA fragments has done nothing short of revolutionizing science. It enables researchers to try and error with particular segments of the human genomic equation to analyze illnesses, design novel treatments, and potentially fashion individual treatments.
How DNA Oligo Synthesis Works
The process of DNA Oligosynthesis involves the synthesis of DNA molecules from nucleotides in a nucleotide-by-nucleotide manner. Cytosine is added after adenine, thymine is added next, then cytosine and guanine are added afterward. This synthesis occurs in small specialized facilities or oligo manufacturing plants, as they are commonly referred to. It is more efficient with input from the user and automated; the researchers input their timescales and receive the sequences they desire from the program.
The beauty of DNA oligo synthesis is its precision. Scientists are able to build the exact sequences related to any region of interest in the genome. It is for this reason that the tool can be regarded as incredibly useful in any research activity. Furthermore, to accomplish this process, an oligo analyzer can be used to examine the purity and accuracy of these sequence elements, fulfilling the needed norms.
Role of DNA Oligo Synthesis in the Research.
DNA oligo synthesis is the focal point of many studies. Researchers apply these synthetic oligonucleotides to gene editing, sequencing, and diagnostics. For example, custom oligos can be used in genetics to help researchers understand mutations and their impact on the body. In drug discovery, it is oligos that identify certain genes that cause certain diseases in the body.
This is quite significant for oligonucleotide drug development, especially those drugs that are made from synthesized oligonucleotides such as DNA and RNA and are designed to handle diseases such as cancer and other inherited disorders. The choice of the DNA sequence is the decisive factor, and that is where the synthesis process is so important. Without these tools, it becomes rather difficult to work on and deliver gene therapies and personalized medicine.
Applications in Biotechnology and Drug Development
In addition to research, DNA oligo synthesis is of great importance in the biotechnology and pharmaceutical industries. Large companies use it to develop diagnostic tools, work on vaccines, and even create oligonucleotide drugs. Oligonucleotides are also used in the pharmaceutical world to create quality patented drugs to target specific disease-causing genes.
This process is backed with oligonucleotide manufacturing companies that produce oligonucleotides in a large scale. These organizations are typically engaged in outsourced CDMO drug development services and provide development services to other companies to launch new therapies to markets.
Conclusion
DNA Oligo Synthesis is one of the most important tools for research work and biotechnology. From exploring the basis of hereditary to facilitating the creation of new treatment methods, this technology is in the heart of many scientific discoveries. Veliter Bio offers a comprehensive range of synthesized oligonucleotides at competitively low prices for research and pharmaceutical industries. For both small research projects that require oligo synthesis in small quantities or commercial scale projects that require large scale oligo synthesiss, we have got you covered.
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Global Peptide And Oligonucleotide CDMO Market Analysis 2024: Size Forecast and Growth Prospects
The peptide and oligonucleotide cdmo global market report 2024from The Business Research Company provides comprehensive market statistics, including global market size, regional shares, competitor market share, detailed segments, trends, and opportunities. This report offers an in-depth analysis of current and future industry scenarios, delivering a complete perspective for thriving in the industrial automation software market.
Peptide And Oligonucleotide CDMO Market, 2024report by The Business Research Company offers comprehensive insights into the current state of the market and highlights future growth opportunities.
Market Size - The peptide and oligonucleotide CDMO market size has grown rapidly in recent years. It will grow from $1.93 billion in 2023 to $2.16 billion in 2024 at a compound annual growth rate (CAGR) of 11.8%. The growth in the historic period can be attributed to a rise in demand for therapeutic agents, advancements in synthesis and manufacturing, personalized medicine trends, regulatory guidelines, and increased focus on antiviral peptides and mRNA vaccines highlighting the potential of oligonucleotides in vaccine development.
The peptide and oligonucleotide CDMO market size is expected to see rapid growth in the next few years. It will grow to $3.39 billion in 2028 at a compound annual growth rate (CAGR) of 12.0%. The growth in the forecast period can be attributed to the growing demand for personalized medicine, advancements in biotechnology, expanding applications, increasing outsourcing, and the growing burden of chronic diseases. Major trends in the forecast period include personalized therapies, technological advancements, quality control challenges, global expansion, and increased collaboration among biopharmaceutical companies.
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Scope Of Peptide And Oligonucleotide CDMO MarketThe Business Research Company's reports encompass a wide range of information, including:
1. Market Size (Historic and Forecast): Analysis of the market's historical performance and projections for future growth.
2. Drivers: Examination of the key factors propelling market growth.
3. Trends: Identification of emerging trends and patterns shaping the market landscape.
4. Key Segments: Breakdown of the market into its primary segments and their respective performance.
5. Focus Regions and Geographies: Insight into the most critical regions and geographical areas influencing the market.
6. Macro Economic Factors: Assessment of broader economic elements impacting the market.
Peptide And Oligonucleotide CDMO Market Overview
Market Drivers -The growing adoption of personalized medicine is expected to propel the growth of the peptide and oligonucleotide CDMO markets going forward. Personalized medicine is an approach to healthcare that tailors medical decisions and treatments to individual characteristics, such as genetics, environment, and lifestyle. The growing adoption of personalized medicine is due to several factors such as advancements in genomic technologies, increased understanding of disease mechanisms at the molecular level, and the demand for more effective and targeted treatment options tailored to individual patients' genetic profiles and medical histories. Peptide and oligonucleotide contract development and manufacturing organizations (CDMOs) play a crucial role in personalized medicine by producing customized therapeutic peptides and oligonucleotides tailored to individual patient needs. For instance, in February 2024, according to the Personalized Medicine Coalition, a UK-based organization promoting the adoption of personalized medicine, the Food and Drug Administration’s (FDA) Center for Drug Evaluation and Research (CDER) approved 16 new personalized treatments for rare disease patients, up from 6 in 2022. Therefore, the growing adoption of personalized medicine is driving the growth of the peptide and oligonucleotide CDMO market.
Market Trends - Major companies operating in the peptide and oligonucleotide CDMO market are focusing on developing strategic partnerships to enhance their service offerings, expand their technological capabilities, and increase their market reach. Peptide development and production partnerships refer to collaborative agreements between two organizations focused on developing and manufacturing peptide-based therapeutics. For instance, in May 2023, PolyPeptide Group AG, a US-based contract development and manufacturing organization (CDMO), partnered with Numaferm GmbH, a Germany-based biotechnology company, for peptide development and production. This partnership aims to utilize PolyPeptide's cGMP manufacturing capacities and market access, along with Numaferm's expertise in sustainable peptide manufacturing and biochemical production platforms. The partnership is focused on jointly exploring the development of suitable peptide candidates with the goal of more sustainable production of peptide-based APIs.
The peptide and oligonucleotide cdmo market covered in this report is segmented –
1) By Product: Peptides, Oligonucleotides 2) By Service Type: Contract Development, Contract Manufacturing, 3) By Application: Therapeutics, Research Applications, Diagnostics, Other Applications 4) By End User: Biopharmaceutical Companies, Pharmaceutical Companies, Research Institutes, Academic and Government Organizations, Others End Users
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Regional Insights - North America was the largest region in the peptide and oligonucleotide CDMO market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the peptide and oligonucleotide cdmo market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
Key Companies - Major companies operating in the peptide and oligonucleotide cdmo market are Thermo Fisher Scientific Inc., Merck KGaA, Ajinomoto Co. Inc., Lonza Group Ag, Wuxi Apptec Co. Ltd., Catalent Inc., Piramal Pharma Ltd, Curia Global Inc., Almac Group, Euroapi SA., CordenPharma International, Bachem Holding AG, Genscript Biotech Corporation, PolyPeptide Group, Rentschler Biopharma SE, Ambiopharm Inc, ScinoPharm, Senn Chemicals AG, Aurigene Pharmaceutical Services, Creative Peptides, Sylentis S.A.
Table of Contents 1. Executive Summary 2. Peptide And Oligonucleotide CDMO Market Report Structure 3. Peptide And Oligonucleotide CDMO Market Trends And Strategies 4. Peptide And Oligonucleotide CDMO Market – Macro Economic Scenario 5. Peptide And Oligonucleotide CDMO Market Size And Growth ….. 27. Peptide And Oligonucleotide CDMO Market Competitor Landscape And Company Profiles 28. Key Mergers And Acquisitions 29. Future Outlook and Potential Analysis 30. Appendix
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New Trends of Oligonucleotide Synthesis Market with Industry Analysis by 2024 – 2030
Oligonucleotide Synthesis Industry Overview
The global oligonucleotide synthesis market size was estimated at USD 3.68 billion in 2023 and is projected to grow at a compound annual growth rate (CAGR) of 13.21% from 2024 to 2030.
The decreasing prices of sequencing have led to increasing demand for custom-made nucleotides for applications across genetic testing, research, forensics applications, and drug development. This has further boosted the demand for oligonucleotide synthesis. The COVID-19 pandemic has affected every market globally and there has been a surge in the demand for efficient treatment against COVID-19.
Gather more insights about the market drivers, restrains and growth of the Oligonucleotide Synthesis Market
Oligonucleotide therapeutics hold immense potential for treating chronic conditions such as cardiovascular diseases, cancers, and retinal disorders. Emerging new applications of oligo sequences in multiple fields of biotechnology are expected to increase market growth. Demand for molecular diagnostics in precision care is an important emerging application field for oligonucleotide synthesis.
The introduction of advanced techniques such as CRISPR and high-throughput sequencing for gene expression analysis has simplified the genetic screening and modification of genomes. Such innovations are observed to influence the demand for oligonucleotide synthesis. Manufacturers invest in technology development to enable the production of long Oligonucleotides with higher precision and better yield to cater to the growing need for custom oligos.
The availability of a regulatory environment that supports the progress of genomics is the key factor contributing to the market growth. Changes in the regulatory policies to provide a well-framed environment for advanced biological research and application in human use are expected to influence demand for oligonucleotide synthesis significantly. Stem cells, regenerative medicine, genetic engineering, and synthetic biology are the prominent fields identified with high potential in healthcare. For instance, the International Society for Stem Cell Research (ISSCR) ethics and public policy committee aims to recognize and resolve issues by conducting open discussions. The committee includes experts in ethics, law, and social policy worldwide.
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The global optical genome mapping market size was valued at USD 104.1 million in 2023 and is expected to grow at a CAGR of 26.76% from 2024 to 2030.
The global therapeutic drug monitoring market size was valued USD 1.80 billion in 2023 and is projected to grow at a CAGR of 3.8% from 2024 to 2030.
Key Companies & Market Share Insights
Some of the key players operating in the market include Merck KGaA, Thermo Fisher Scientific, Inc., and Agilent Technologies. These players focus on business strategies such as partnerships/collaborations, product launches, and expansion. Twist Bioscience, Biolegio, and LGC Biosearch Technologies are some of the emerging market participants in the oligonucleotide market. These players primarily focus on expansion and partnerships to strengthen their position in the market.
Key Oligonucleotide Synthesis Companies:
· Thermo Fisher Scientific, Inc.
· Merck KGaA
· Danaher Corporation
· Dharmacon Inc.
· Agilent Technologies
· Bio-synthesis
· Kaneka Eurogentec S.A
· LGC Biosearch Technologies
· Biolegio
· Twist Bioscience
Recent Developments
In October 2023, IDT inaugurated a new therapeutic manufacturing facility to meet the increasing demand in genomic medicine. The new facility is equipped to support the production of therapeutic oligonucleotides, catering to the expanding needs in the field of genomics and personalized medicine.
In September 2023, Danaher Corporation (Integrated DNA Technologies) introduced a range of xGen NGS products tailored for the Ultima Genomics UG 100TM platform. The suite includes adapters, primers, and universal blockers, catering to various applications such as DNA, RNA, & methylation sequencing workflows. This offering is complemented by IDT's proven hybridization capture chemistry, enhancing versatility for researchers.
In July 2023, Analytix introduced two new instruments designed for organic synthesis, including wavePREP, tailored for oligonucleotide synthesis, and Xelsius, a workstation for multireaction synthesis.
In May 2023, GenScript expanded its life sciences facility in Zhenjiang, Jiangsu, China, to offer a rapid, high-purity oligonucleotide and peptide synthesis service tailored for research & development as well as preclinical applications.
In May 2023, Twist Bioscience and CeGaT GmbH launched the Twist Alliance CeGaT RNA Fusion Panel. This collaborative effort aims to provide a specialized tool for oncology research, facilitating the detection of RNA fusions and enabling transcript variant analysis. RNA fusions, a result of chromosomal arrangements often seen in cancers, can now be efficiently studied using this newly introduced panel.
In February 2023, Fluor Corp. and Agilent Technologies, Inc. collaborated to enhance its oligonucleotide therapeutics manufacturing facility in Frederick, Colorado. Under this collaboration, Fluor is expected to support the project's engineering and procurement. The total value of the project is evaluated at USD 725 million.
Order a free sample PDF of the Oligonucleotide Synthesis Market Intelligence Study, published by Grand View Research.
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Global DNA Encoded Library Market Will Grow At Highest Pace Owing To Rising Demand For Targeted Drug Discovery
DNA encoded library is an innovative approach that employs DNA sequences to encode large chemical libraries for drug discovery. DNA encoded libraries provide advantages like screening of millions of compounds in parallel and facilitating drug discovery research. The technique involves encoding large collections of small molecules, peptides or oligonucleotides with short DNA tags and then screening them for potential hits. This enables high-throughput screens focusing on specific targets for applications in drug discovery, chemical biology and systematic evolution of ligands by exponential enrichment (SELEX).
The Global DNA Encoded Library Market is estimated to be valued at US$ 0.8 Bn in 2024 and is expected to exhibit a CAGR of 16% over the forecast period 2024-2031.
Key Takeaways
Key players operating in the Global DNA Encoded Library are BOC Sciences, DyNAbind, Edelris, GenScript, and HitGen. These players are adopting strategies like collaborations, investments in R&D and new product launches to strengthen their market position. The growing demand for effective therapeutics against various diseases is also boosting the demand for DNA encoded library-based drug discovery worldwide. Additionally, technological advancements like next generation sequencing and mass spectrometry is further enhancing the screening capabilities and fueling the growth of this market.
Market Trends
Some of the key trends driving the growth of the Global DNA Encoded Library market include rising adoption of DNA-encoded library techniques by pharmaceutical companies and growth of clinical trials. The traditional drug discovery methods are being replaced with DNA-encoded techniques owing to their advantages. They enable screening libraries of billions of compounds efficiently in a high-throughput manner. Another trend is the increasing partnerships between technology providers and end-users to accelerate the drug discovery process using DNA-encoded library platforms.
Market Opportunities
The untapped potential of emerging economies and growing research in genomic applications presents huge opportunities for players in this market. Rapid advances in DNA synthesis and sequencing technologies are further expanding the applications of DNA-encoded libraries. Adoption of artificial intelligence and machine learning can also enhance the screening and data analysis capabilities. Development of customized DNA-encoded libraries focused on specific disease pathways will witness high demand in coming years.
Impact Of Covid-19 On Global DNA Encoded Library Market Growth:
The outbreak of Covid-19 pandemic severely impacted the growth of global DNA encoded library market in the initial months of 2020. Various social restrictions imposed by governments like lockdowns and social distancing norms disrupted the supply chain and halted research activities at labs and research institutions globally. This led to delays in drug discovery programs utilizing DNA encoded libraries. Many biopharma companies also shifted resources to focus on Covid-19 vaccine and treatment research in the short term.
However, as research communities and industries adapted to the new normal, activity levels recovered gradually in 2021. The pandemic also highlighted the importance of therapeutics for infectious diseases, boosting investment in areas like antibiotic discovery utilizing DNA encoded libraries. Many players in the market also expedited development of Covid-19 antiviral and treatment libraries. Going forward, market players are focusing on digitalization of operations and remote collaborations to make discovery processes more resilient to future disruptions. Governments are also providing increased funding for genomics and biotech to accelerate development of new drugs.
Concentration Of Global DNA Encoded Library Market In Terms Of Value:
North America region currently accounts for the largest share of global DNA encoded library market in terms of value, estimated at over 40% in 2024. This is due to presence of major pharmaceutical players and contract research organizations (CROs) actively utilizing these libraries for drug discovery programs in the US and Canada. Countries like the US also provide favorable funding environment for genomic and biotech research. Europe is the second largest regional market led by presence of large pharma companies and academic research institutes in countries like UK, Germany and France. The market is also witnessing fastest growth in Asia Pacific region led by China and India. This is attributed to increasing government investments in healthcare sector, emerging biotech industry and growing expertise in DNA sequencing and library construction technologies.
Fastest Growing Region In The Global DNA Encoded Library Market:
Asia Pacific region is poised to emerge as the fastest growing regional market for DNA encoded libraries during the forecast period from 2024 to 2031. This growth can be attributed to increasing government emphasis and funding for research in genomics, biotech and synthetic biology in emerging economies like China and India. Favorable business environment and presence of skilled labor are also attracting many global library developers and pharmaceutical companies to set up research and manufacturing facilities in the region. In addition, the region provides significant cost advantages compared to developed markets for drug discovery processes. With improving standards and widespread adoption of DNA encoded library technologies, Asia Pacific will continue dominating the growth of worldwide market in the coming years.
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Author Bio:
Money Singh is a seasoned content writer with over four years of experience in the market research sector. Her expertise spans various industries, including food and beverages, biotechnology, chemical and materials, defense and aerospace, consumer goods, etc. (https://www.linkedin.com/in/money-singh-590844163 )
What Are The Key Data Covered In This Global DNA Encoded Library Market Report?
:- Market CAGR throughout the predicted period
:- Comprehensive information on the aspects that will drive the Global DNA Encoded Library Market's growth between 2024 and 2031.
:- Accurate calculation of the size of the Global DNA Encoded Library Market and its contribution to the market, with emphasis on the parent market
:- Realistic forecasts of future trends and changes in consumer behaviour
:- Global DNA Encoded Library Market Industry Growth in North America, APAC, Europe, South America, the Middle East, and Africa
:- A complete examination of the market's competitive landscape, as well as extensive information on vendors
:- Detailed examination of the factors that will impede the expansion of Global DNA Encoded Library Market vendors
FAQ’s
Q.1 What are the main factors influencing the Global DNA Encoded Library Market?
Q.2 Which companies are the major sources in this industry?
Q.3 What are the market’s opportunities, risks, and general structure?
Q.4 Which of the top Global DNA Encoded Library Market companies compare in terms of sales, revenue, and prices?
Q.5 Which businesses serve as the Global DNA Encoded Library Market’s distributors, traders, and dealers?
Q.6 How are market types and applications and deals, revenue, and value explored?
Q.7 What does a business area’s assessment of agreements, income, and value implicate?
*Note: 1. Source: Coherent Market Insights, Public sources, Desk research 2. We have leveraged AI tools to mine information and compile it
#Global DNA Encoded Library Market Trend#Global DNA Encoded Library Market Size#Global DNA Encoded Library Market Information#Global DNA Encoded Library Market Analysis#Global DNA Encoded Library Market Demand
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Active Pharmaceutical Ingredients Market: Key Companies and Emerging Trends 2024-2030
The global active pharmaceutical ingredients market size was estimated at USD 237.47 billion in 2023 and is expected to grow at a compound annual growth rate (CAGR) of 5.75% from 2024 to 2030.
Advancements in Active Pharmaceutical Ingredient (API) manufacturing, growth of the biopharmaceutical sector, and an increase in geriatric population are among the key drivers of API market. An increase in prevalence of chronic diseases, such as cardiovascular diseases and cancer, is anticipated to boost market growth.
Global geriatric population is increasing. According to UN, in 2022, people aged 65 and above accounted for 771 million of the population, and the number is anticipated to reach 994 million by 2030 to 1.6 billion by 2050. The number of elderly people is showing fastest growth in Africa, with a threefold increase estimated in people aged 60 and above, followed by Latin America, reaching 18.8 billion by 2050. Aging is considered the greatest risk factor for development of diseases, including cardiovascular and neurological diseases. Thus, rapidly growing global geriatric population is resulting to be a high-impact-rendering driver for API market.
Gather more insights about the market drivers, restrains and growth of the Active Pharmaceutical Ingredients Market
Increasing prevalence of infectious diseases and hospital-acquired infections is driving market growth. In addition, growing incidence of cardiovascular, genetic, and neurologic disorders is anticipated to act as a high-impact-rendering driver for market growth. Cardiovascular Diseases (CVDs) are the most prevalent causes of death globally. According to WHO, cardiovascular diseases cause death of 17.9 million people per day and are expected to cause approximately 25 million deaths by 2030. Increasing epidemiology of lifestyle, aided with rising number of smokers globally, growing incidence of obesity, and increasing dietary irregularities, are factors likely responsible to propel market growth. A recent report by the United Nations (UN) in May 2023 suggests that there has been a 75% increase in the number of girls and 61% in the number of boys with obesity in Europe.
Outsourcing of APIs has become profitable over in-house production. However, this trend took a different turn during the COVID-19 pandemic. Companies are looking to diversify their API suppliers and manufacturers to different locations instead of outsourcing it to just one manufacturer. In addition, risk mitigation is done using dual sourcing to ensure a continuous supply. Hence, key companies aim to capitalize on this ongoing outsourcing trend with new acquisitions. For instance, in August 2023, EUROAPI announced its deal to acquire BianoGMP to enhance its CDMO expertise in oligonucleotide manufacturing, which is a high-growth industry. This further demonstrates the company’s plans for vertical integration.
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• The global antipsychotic drugs market size was valued at USD 16.88 billion in 2023 and is projected to grow at a CAGR of 6.1% from 2024 to 2030.
• The global drug and gene delivery devices market size was valued at USD 670.0 million in 2023 and is projected to grow at a CAGR of 9.0% from 2024 to 2030.
Active Pharmaceutical Ingredients Market Report Segmentation
Grand View Research has segmented the global active pharmaceutical ingredients market report based on type of synthesis, type of manufacturer, type, application, type of drug, and region:
Type of Synthesis Outlook (Revenue, USD Billion, 2018 - 2030)
• Biotech
o Biotech APIs Market, By Type (Revenue, USD Billion, 2018 - 2030)
o Generic APIs
o Innovative APIs
o Biotech APIs Market, By Product (Revenue, USD Billion, 2018 - 2030)
o Monoclonal Antibodies
o Hormones
o Cytokines
o Recombinant Proteins
o Therapeutic Enzymes
o Vaccines
o Blood Factors
• Synthetic
o Synthetic APIs Market, By Type (Revenue, USD Billion, 2018 - 2030)
o Generic APIs
o Innovative APIs
Type of Manufacturer Outlook (Revenue, USD Billion, 2018 - 2030)
• Captive APIs
• Merchant APIs
Type Outlook (Revenue, USD Billion, 2018 - 2030)
• Generic APIs
• Innovative APIs
Application Outlook (Revenue, USD Billion, 2018 - 2030)
• Cardiovascular Diseases
• Oncology
• CNS and Neurology
• Orthopedic
• Endocrinology
• Pulmonology
• Gastroenterology
• Nephrology
• Ophthalmology
• Others
Key Companies & Market Share Insights
Some of the leading players operating in the active pharmaceutical ingredients market include AbbVie, Inc., Novartis AG, Regeneron Pharmaceuticals, Inc., and Eli Lilly and Company. Key players are using existing customer bases in the region to prioritize maintaining high-quality standards and gain high market size access. This marketing strategy is useful for brands that have already built trust in the market. These players are heavily investing in advanced technology and infrastructure, allowing them to efficiently process & analyze a large volume of samples. Moreover, companies undertake various strategic initiatives with other companies and distributors to strengthen their market presence.
Evonik, CARBOGEN AMCIS, and Pharmazell, are some of the emerging market participants in the ophthalmic drugs market. These companies focus on achieving funding support from government bodies and healthcare organizations aided with novel product launches to capitalize on untapped avenues.
Key Active Pharmaceutical Ingredients Companies:
• Dr. Reddy’s Laboratories Ltd.
• Sun Pharmaceutical Industries Ltd.
• Teva Pharmaceutical Industries Ltd.
• Cipla Inc.
• AbbVie Inc.
• Aurobindo Pharma
• Sandoz International GmbH (Novartis AG)
• Viatris Inc.
• Fresenius Kabi AG
• STADA Arzneimittel AG
Recent Developments
• In August 2023, EUROAPI announced its deal to acquire BianoGMP to enhance its CDMO expertise in oligonucleotide manufacturing, which is a high-growth industry.
• In July 2023, Teva Pharmaceutical Industries Ltd. designed a new strategy for development with potential sale of its API unit on the table. The API manufacturing facility is worth USD 2 billion.
• In June 2023, Lonza acquired Synaffix to improve its ADC services portfolio.
• In April 2023, Eli Lilly announced an investment of USD 1.6 billion in the U.S.-based LEAP Innovation Park. This brings the total investment to USD 3.7 billion to manufacture complex APIs for products such as genetic medicine.
• In February 2023, Lonza completed the manufacturing of its facility in Switzerland. The company enhanced its capacity for its High Potent Active Pharmaceutical Ingredient (HPAPI) manufacturing facility.
• In January 2023, Sterling Pharma Solutions acquired an API manufacturing facility from Novartis in Ringaskiddy, Ireland.
Order a free sample PDF of the Active Pharmaceutical Ingredients Market Intelligence Study, published by Grand View Research.
#Active Pharmaceutical Ingredients Market#Active Pharmaceutical Ingredients Industry#Active Pharmaceutical Ingredients Market size#Active Pharmaceutical Ingredients Market share
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Oligonucleotide Synthesis Market is Expected to Witness High Growth Owing to Rising Biotechnology Research and Development
The oligonucleotide synthesis market involves the production of shorter sequences of nucleic acids known as oligonucleotides that are widely used in research, diagnostics and therapeutics applications. Oligonucleotides play a vital role in gene expression studies, next-generation sequencing, DNA & RNA analysis, qPCR and molecular diagnostics. The increasing focus on biotechnology research especially in life sciences and genomics has boosted the demand for specialized oligonucleotides.
The Global oligonucleotide synthesis market is estimated to be valued at US$ 4565 Bn in 2024 and is expected to exhibit a CAGR of 13% over the forecast period of 2024 to 2031.
Key Takeaways Key players operating in the oligonucleotide synthesis are Forte Research Systems (India), ICON plc (Ireland), Merge healthcare incorporated (U.S.), Bio-Optronics (U.S.), DSG INC (U.S.), ArisGlobal (India), ERT Clinical Bioclinica (U.S.), Oracle Corporation (U.S.), Medidata Solutions (U.S.), DATATRAK International, Inc. (U.S.), and MedNet Solutions, Inc., (U.S.) among others. These key players are focusing on partnerships and new technology development to expand their oligonucleotide synthesis capabilities.
Key Oligonucleotide Synthesis Market Demand include increasing research in personalized medicine and precision genomics. Additionally, the growing pipeline of oligo-based drugs and clinical trials for rare diseases will provide momentum.
With regards to geographical expansion, North America dominates the global oligonucleotide synthesis market followed by Europe. However, Asia Pacific is expected to witness highest growth rate owing to increasing government support for biotech sector and growing industry investments in China and India.
Market Drivers Increasing R&D expenditure for biotechnology research especially in life sciences and biopharmaceutical industry is a key factor contributing to the Oligonucleotide Synthesis Market Size And Trends Oligonucleotides play a vital role in new drug discovery and development which is propelling many biotech companies to adopt oligo synthesis. Rising applications of oligos in development of advanced therapeutics like antisense oligonucleotides and siRNA is expected to drive the market during the forecast period.
PEST Analysis Political: Government regulations around drug research and development have an impact. Changes in healthcare policies and funding also affect the market. Economic: The state of the economy influences research spending by pharmaceutical companies and academic institutions, affecting demand. Rising healthcare costs drive need for new drug therapies. Social: An aging global population with increased prevalence of diseases like cancer is leading to higher demand for advanced drug development and diagnostic tools. Social attitudes around health and biotech also evolve over time.
Technological: Advancements in DNA sequencing, synthesis and analysis technologies enable new applications and drive down costs, expanding the potential market. Automation and artificial intelligence are enhancing R&D productivity.
North America holds the largest share in terms of value currently due to heavy spending on drug R&D by major players in the US and Canada. However, Asia Pacific is expected to grow at the fastest rate during the forecast period as the pharmaceutical industry expands rapidly in major emerging economies like China and India. These countries are making large investments in research and increasing regulatory approvals are also supporting market growth.
Europe accounts for a sizable share as well owing to extensive government funding for research programs. However, the high costs of oligonucleotide therapies has limited their use thus far. If pricing and reimbursement improve in the future, the European market could witness stronger growth. On the other hand, the Middle East and Africa region is relatively nascent but demand may rise over time with economic development across various nations. Get More Insights On, Oligonucleotide Synthesis Market About Author: Ravina Pandya, Content Writer, has a strong foothold in the market research industry. She specializes in writing well-researched articles from different industries, including food and beverages, information and technology, healthcare, c
#Oligonucleotide Synthesis Market Size#Oligonucleotide Synthesis Market Trends#Oligonucleotide Synthesis Market Analysis#Oligonucleotide Synthesis#Oligonucleotide Synthesis Market
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Global Oligonucleotide Synthesis Market Market Size, Share, Trends, Demand, Growth and Competitive Analysis
Oligonucleotide Synthesis Market research report has been prepared with the systematic gathering and evaluation of market information for industry which is presented in a form that explains various facts and figures to the business. Report saves valuable time as well as adds credibility to the work that is performed to grow business. This quality report has been planned with full commitment and transparency in research and analysis. With the systematic insights of this report, companies can self-assuredly take decisions about the production and marketing strategies. Oligonucleotide Synthesis Market document provides the same by studying the market and the industry with respect to numerous aspects.
Oligonucleotide Synthesis Market report gives explanation about the different segments of the market analysis which is demanded by today’s businesses. Key players are taking actions such as developments, product launches, acquisitions, mergers, joint ventures and competitive analysis in the industry. All the market aspects are estimated and analysed by a team of innovative, enthusiastic and motivated researchers and analysts so that nothing lefts uncovered in the report. Global Oligonucleotide Synthesis Market research report, it becomes easy to figure out brand awareness and insight about the brand and product among potential customers.
Oligonucleotide Synthesis Market, By Product (Oligonucleotide, Reagents, and Equipment), Type (Custom Oligos and Predesigned Oligos), Application (Therapeutic Applications, Diagnostics, Research, and Others), End User (Academic Research Institutes, Pharmaceutical and Biotechnology Companies, Diagnostic Laboratories and others) - Industry Trends and Forecast to 2030.
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The report provides insights on the following pointers:
Market Penetration: Comprehensive information on the product portfolios of the top players in the Oligonucleotide Synthesis Market.
Product Development/Innovation: Detailed insights on the upcoming technologies, R&D activities, and product launches in the market.
Competitive Assessment: In-depth assessment of the market strategies, geographic and business segments of the leading players in the market.
Market Development: Comprehensive information about emerging markets. This report analyzes the market for various segments across geographies.
Market Diversification: Exhaustive information about new products, untapped geographies, recent developments, and investments in the Oligonucleotide Synthesis Market.
Global Oligonucleotide Synthesis Market survey report analyses the general market conditions such as product price, profit, capacity, production, supply, demand, and market growth rate which supports businesses on deciding upon several strategies. Furthermore, big sample sizes have been utilized for the data collection in this business report which suits the necessities of small, medium as well as large size of businesses. The report explains the moves of top market players and brands that range from developments, products launches, acquisitions, mergers, joint ventures, trending innovation and business policies.
The following are the regions covered in this report.
North America [U.S., Canada, Mexico]
Europe [Germany, UK, France, Italy, Rest of Europe]
Asia-Pacific [China, India, Japan, South Korea, Southeast Asia, Australia, Rest of Asia Pacific]
South America [Brazil, Argentina, Rest of Latin America]
The Middle East & Africa [GCC, North Africa, South Africa, Rest of the Middle East and Africa]
This study answers to the below key questions:
What are the key factors driving the Oligonucleotide Synthesis Market?
What are the challenges to market growth?
Who are the key players in the Oligonucleotide Synthesis Market?
What are the market opportunities and threats faced by the key players?
Some of the major players operating in the global oligonucleotide synthesis market are:
Agilent Technologies, Inc. (U.S.)
Atdbio Ltd.(U.K.)
LGC Limited (U.K.)
Bio-Synthesis Inc.(U.S.)
Eurofins Genomics (India),
Kaneka Eurogentec S.A.(Belgium)
General Electric (U.S.)
Genscript (U.S.)
AJINOMOTO CO.,INC (Genedesign, Inc.) (Tokyo)
Danaher (U.S.)
Merck Kgaa (Germany)
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The Fate of Oligonucleotide Medications
Oligonucleotide drugs are rapidly gaining a central place in todayÕs pharmaceutical industry. These synthetic molecules of DNA or RNA are meant for selective action on definite genes associated with diseases. This makes oligonucleotide drugs development different from most other drugs, which target proteins or enzymes, because, in principle, one could design drugs that alter genetic activity. This indicates that there can be fresh approaches for managing many disorders, including inherited disorders, cancer, and diabetes.
Advancements in Oligonucleotide Manufacturing
The biggest issue in the oligonucleotide drug development process has been synthesis. The synthesis of good quality oligonucleotides is a process that needs special attention and skill. However, these challenges are being witnessed in the oligonucleotide manufacturing and are deformities, advanced in the synthesis of oligonucleotide have been enabling. The availability of sophisticated instruments enables many oligonucleotide manufacturing companies to be established in the market.
Notably, recent advances in large-scale oligo synthesis make these drugs more readily available to patients. This is a big leap towards increasing the ability to manufacture oligonucleotide drugs at an industrial scale in various parts of the world.
Personalized Medicine and Custom Oligos
Another interesting option for oligonucleotide drugs is individual production of custom oligonucleotide synthesis. This means that therapies can be made according to the patient's genetic structure. HSOs can be synthesized specifically to hit one gene behind a given disease, and this application cannot be had with other drugs.
This ability to develop personalized medicine could, therefore, transform the management of rare genetic ailments among patient populations. As oligo synthesis companies refine their technique, they will develop more targeted treatment services and, therefore, make personalized medicine a possibility.
The Role of Oligo CDMO in Drug Development
Oligo CDMO is a key enabler of these therapies with Contract Development and Manufacturing Organizations. These organizations focus on both the synthesis and production of oligonucleotide drugs, and guide pharmaceutical firms on the challenges of oligonucleotide manufacturing process.
CDMOs contribute to the acceleration of drug development through offering production know-how, quality control and regulatory knowledge. As the consumption of oligonucleotide drugs increases, oligoCDMOs will play an increasingly significant part.
The Future of RNA Oligo Synthesis
Another area of RNA oligo synthesis that we are likely to see much further development is RNA targets. These targets are discussed for potential treatment of cancer, viral disorders, and autoimmune responses. RNA oligonucleotides' effectiveness increases as RNA production advances, and there is hope for treatments as it creates more chances.
As it stands, Rna Synthesis Company are making formidable research efforts toward novel treatment regimens, and the perspective for RNA-based therapies is optimistic. The ability to change RNA directly and regulate the messages converting to proteins can be a good pharmaceutical prospect.
Conclusion
The future for oligonucleotide drugs is bright as we look forward to the future of this platform. As oligo manufacturing has progressed and Oligo CDMOs have entered the scene, these drugs are more available and functional. As the dream of personalized medicine comes to pass, PNA synthesis will provide a molecule that can be adapted to the genetically oriented ailment. Here at Veliter Bio, we are on the cutting edge of this rapidly growing fieldÑoffering the best oligo solutions that will drive the advancement of medicine.
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DNA Synthesizer Market is Estimated to Witness High Growth Owing to Increasing Demand for Custom DNA
DNA synthesizers are used for the chemical synthesis of DNA and oligonucleotides in research and diagnostic laboratories. They provide an efficient and cost-effective solution for DNA assembly and custom DNA synthesis for applications in gene editing, genomics, and molecular biology research.
Market Dynamics:
The growth of the DNA synthesizer market is driven by the increasing demand for custom DNA due to applications in gene editing and genomics research. CRISPR/Cas9 technology is being widely adopted for gene editing applications and is driving demand for custom DNA. Additionally, growing genomics research for studying genetic mutations and biomarkers of diseases is also fueling market growth. Additionally, technological advancements in DNA synthesis techniques allowing for longer oligo synthesis at lower costs is further supporting market expansion over the forecast period.
DNA Synthesizer Market Drivers
Increasing Applications of DNA in Biotechnology and Pharmaceutical Industry
The growing applications of DNA in biotechnology and pharmaceutical research is one of the major drivers fueling the growth of the global DNA synthesizer market. DNA synthesizers play a vital role in DNA amplification, sequencing and genetic modification which are extensively used in various biotechnology and pharmaceutical applications such as drug discovery, vaccine development, genomics, proteomics, and gene therapy research. According to the World Health Organization, global expenditure on pharmaceutical R&D rose to almost USD 179 billion in 2018 from USD 165 billion in 2017. This rising investment in pharmaceutical R&D is creating strong demand for various DNA technologies including DNA synthesizers.
Advancing Technology and Automation in DNA Synthesizers
Advancements in DNA synthesizer technology and increasing level of automation are positively impacting the market growth. DNA synthesizers with advanced features such as miniaturization, increased throughput, enhanced accuracy and productivity are gaining more popularity among end users. Continuous technological innovations are enabling manufacturers to introduce smaller, more efficient and automated DNA synthesizers. For instance, in 2019, Agilent Technologies launched the next generation nucleotide solution kit and workflow software for DNA synthesis further automating the synthesis process and shortening research cycle times while improving accuracy. Such innovations are expected to further accelerate the adoption of DNA synthesizers.
DNA Synthesizer Market Restrain
High Cost of DNA Synthesizers
The high cost associated with the purchase of DNA synthesizers is a major factor hindering the growth of this market. Due to high precision capabilities and advanced features, DNA synthesizers come at a very high initial purchase price which is a significant barrier, particularly for small and medium research laboratories and institutes with budget constraints. For instance, basic DNA synthesizers with limited features cost anywhere between USD 20,000 to USD 100,000 while advanced DNA synthesizers compatible for automation and high throughput screening may cost over USD 200,000 which is a huge investment for most end users. In emerging economies, limited funding for biomedical and biotechnology research also adversely impacts market development to some extent.
DNA Synthesizer Market Opportunity
Increasing Research Activities in Developing Countries
Developing countries in Asia Pacific and Latin America region are witnessing rising investments in biomedical and biotechnology research from both public and private organizations. This growing focus towards bioscience research in developing nations presents significant growth opportunity for DNA synthesizer market players. Additional funding for life science research, increasing number of collaborations between academic institutions and industry, establishment of bioscience clusters and investment in infrastructure are some of the factors fueling opportunities. Moreover, economic growth in developing countries is enabling improved access to advanced technologies, further driving DNA synthesizers demand for academic and industrial applications. Market players can leverage this opportunity by strengthening their distribution networks and offering favorable financing options in developing markets.
DNA Synthesizer Market Trends
Advent of Cost-Effective Solid-Phase Automated DNA Synthesizers
One of the prominent trends shaping the future of DNA synthesizer market is the emergence of cost-effective solid-phase automated synthesizers. Traditionally, DNA synthesizers based on phosphoramidite chemistry were expensive and required highly skilled professionals for complex programming and operation. However, recent offerings by firms such as Merck KGaA and GenScript are changing market dynamics by introducing affordable benchtop synthesizers compatible for multiple reactions to be performed simultaneously. These new generation solid-phase synthesizers have dramatically reduced the overall cost per base DNA synthesis. Further, their ease of use and touchscreen interfaces eliminate the need for advanced programming skills. This trend of low-cost automated solid-phase synthesizers with simplified workflows is making DNA synthesis more accessible and opening up market opportunity beyond traditional core end users.
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