#Nephrotic Syndrome

[biology-geology-beaches-india]

The Science Manuscripts of Satyendra Sunkavally, page 41.

[creativeera]

Frasier Syndrome: Unraveling the Mysteries of a Rare and Progressive Genetic Condition

Cryptophthalmos syndrome, also known as Frasier-Noonan-Costello syndrome, is a very rare genetic disorder characterized by premature accelerated aging. It is caused by mutations in the PTPN11 gene, which provides instructions for making a protein called SHP-2. Signs and Symptoms of Frasier Syndrome

Some of the key signs and symptoms of Cryptophthalmos syndrome include:

- characteristic facial features like sagging jowls, sparse hair, bushy eyebrows, and small ears and mouth.

- short stature and bone age delays with bone overgrowth resulting in bent joints.

- accelerated aging process that can cause heart problems, joint and skin issues at a young age. Frasier Syndrome causes someone with this syndrome to physically appear older than their chronological age.

- intellectual disabilities and learning difficulties ranging from mild to severe. Developmental delays are common.

- heart abnormalities like pulmonary stenosis which is the narrowing of the pulmonary valve that regulates blood flow from the heart to the lungs. This requires surgery in many cases. - bleeding disorders due to platelet dysfunction. Platelets help form blood clots.

Get more insights on Frasier Syndrome

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Vaagisha brings over three years of expertise as a content editor in the market research domain. Originally a creative writer, she discovered her passion for editing, combining her flair for writing with a meticulous eye for detail. Her ability to craft and refine compelling content makes her an invaluable asset in delivering polished and engaging write-ups.

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[drsheltonpamela]

Ce médicament est un « bon médicament » pour prévenir l’apparition de l’urémie ! L’utilisation précoce présente de nombreux avantages!

[pediatric-nephrologist]

What is Nephrotic syndrome? | Dr. Sidharth Kumar Sethi

Nephrotic syndrome is characterized by edema, proteinuria, hypoalbuminemia, and hyperlipidemia. Minimal change disease, the most common cause in childhood, generally responds to corticosteroids, although most patients experience disease relapses. Focal segmental glomerulosclerosis is usually resistant to corticosteroids and carries a significant risk of kidney failure, necessitating renal transplantation. Nephrotic syndrome may also be secondary to gene mutations and systemic diseases such as lupus. Clinical evaluation involves distinguishing primary and secondary causes and monitoring for disease complications, including blood clots and serious infections such as spontaneous bacterial peritonitis. Immunosuppressive medications are used to prevent relapses and treat corticosteroid-resistant disease.

Dr. Sidharth Kumar Sethi

Kidney & Urology Institute

He was trained as a Fellow (International Pediatric Nephrology Association Fellowship) and Senior Resident in Pediatric Nephrology at All India Institute of Medical Sciences and Division of Pediatric Nephrology and Transplant Immunology, Cedars Sinai Medical Centre, Los Angeles, California. He has been actively involved in the care of children with all kinds of complex renal disorders, including nephrotic syndrome, tubular disorders, urinary tract infections, hypertension, chronic kidney disease, and renal transplantation. He has been a part of 8-member writing committee for the guidelines of Steroid Sensitive Nephrotic Syndrome and Expert committee involved in the formulation of guidelines of Pediatric Renal Disorders including Steroid Resistant Nephrotic Syndrome and urinary tract infections. He has more than 30 indexed publications in Pediatric Nephrology and chapters in reputed textbooks including Essential Pediatrics (Editors O.P. Ghai) and “Pediatric Nephrology” (Editors A Bagga, RN Srivastava). He is a part of Editorial Board of “World Journal of Nephrology” and “eAJKD- Web version of American Journal of Kidney Diseases”. He is a reviewer for Pediatric Nephrology related content for various Pediatric and Nephrology journals.

TAG- Paediatric Nephrologist in Delhi, Nephrotic syndrome Specialist in India

[mindfulnutritionsblog]

Why Reducing Sodium and Fluid Intake is Crucial for Kids with Nephrotic Syndrome

Did you know that about 12 in every 100,000 children in India are affected by nephrotic syndrome each year? Nephrotic syndrome is a kidney disorder that can cause significant health problems if not managed properly. One of the most important steps in managing this condition is reducing sodium and fluid intake. This might sound simple, but it can make a big difference in a child's health. Additionally, consulting with the best nephrologists in India can provide expert guidance and tailored treatment plans to ensure the best possible outcomes for affected children.

Engaging Stat: 

Approximately 12 in 100,000 children in India are diagnosed with nephrotic syndrome annually, highlighting the importance of dietary management for better health outcomes.

The Importance of Dietary Changes:

Nephrotic syndrome causes the kidneys to leak protein into the urine, leading to swelling, especially in the legs and around the eyes. High sodium intake can worsen this swelling, making the condition harder to manage. Excess fluid intake can also increase swelling and blood pressure, putting extra strain on the kidneys. By reducing sodium and fluid intake, children with nephrotic syndrome can prevent these complications and improve their overall health.

Understanding the Benefits:

Lowering sodium and fluid intake helps control swelling and blood pressure, reducing the burden on the kidneys. This can lead to fewer hospital visits and a better quality of life for children. Parents might worry about how to limit these elements in their child's diet. However, many resources and recipes are available to make this transition easier. Choosing fresh fruits and vegetables over processed foods can significantly reduce sodium intake.

Making Healthier Choices:

Parents and children must work together to choose healthier options. Reducing sodium and fluid doesn't mean bland food or constant thirst. Many delicious, low-sodium recipes can be both satisfying and nutritious. It's also essential to teach children about the importance of these dietary changes. By making them part of the decision-making process, kids are more likely to stick to the guidelines. 

Five Steps for a healthier you:

Start by gradually reducing the amount of salt in your child's diet. Replace high-sodium snacks with fruits, vegetables, and homemade treats. Encourage your child to drink water instead of sugary drinks and limit their intake of soups and sauces that are often high in sodium. Regularly check food labels to make informed choices. 

Gradually Reduce Salt: Start by slowly decreasing the amount of salt in your child's diet. This helps their taste buds adjust to less salty flavors over time.

Choose Healthy Snacks: Replace high-sodium snacks like chips and processed foods with healthier options such as fresh fruits, vegetables, and homemade treats.

Encourage Water Consumption: Promote drinking water instead of sugary drinks, which can contain hidden sodium and extra calories.

Limit High-Sodium Foods: Reduce your child's intake of foods like soups and sauces, which are often high in sodium. Opt for low-sodium or homemade versions whenever possible.

Check Food Labels: Regularly read food labels to identify and avoid high-sodium products. Look for items labeled as "low sodium" or "no added salt."

Conclusion:

In India, managing nephrotic syndrome is a significant challenge, but with the right dietary changes, children can lead healthier lives. Reducing sodium and fluid intake plays a crucial role in controlling symptoms and preventing complications. About 12 in every 100,000 children in India struggle with this condition each year. By making simple yet effective changes to their diet, families can help their children feel better and avoid hospital visits. Have you considered how these dietary adjustments could benefit your child? With the right approach, managing nephrotic syndrome becomes much more manageable. Additionally, seeking advice from the best doctors for nephrotic syndrome treatment in India can provide valuable guidance and ensure that your child receives the most effective care.

FAQ’s:

Q1: What is nephrotic syndrome?Nephrotic syndrome is a kidney disorder that causes the body to excrete too much protein in the urine, leading to swelling, especially in the legs and around the eyes.

Q2: Why is reducing sodium important for children with nephrotic syndrome?Reducing sodium helps to control swelling and lower blood pressure, making it easier for the kidneys to function properly.

Q3: How can I reduce sodium in my child’s diet?You can reduce sodium by avoiding processed and packaged foods, using fresh ingredients, and seasoning foods with herbs and spices instead of salt.

[nuhospitals24]

General Nephrology | NU Hospitals

General Nephrology deals with the treatment and management of Nephrotic Syndrome, Acute Nephritic Syndrome, Acute Renal Failure, and Chronic Renal Failure.

[pediatric-nephrology-india]

Child Kidney Doctor in India

Child Kidney Doctor in India

Dr Sethi at Medanta, The Medicity is the leading Pediatric Nephrologist providing diagnostic and treatment services for children with conditions of the kidney, especially Nephrotic syndrome, Glomerular disorders, rare tubular disorders and Chronic Kidney disease. Our team is the leading dialysis and renal transplant service center for children.

Dr Sethi & team believes in personalized care that focuses on individual patient and family needs. Our team understands the challenges many of our families face when trying to access the care they need. Our caring goes beyond diagnostics and treatment. Our team is nationally recognized for their innovation, experience, dedication and expertise. We have the newest dialysis technology and provides comprehensive kidney transplant care to children of all ages.

To schedule an appointment With Child Kidney Doctor in India, please contact: Name: Pediatric Nephrology India Address: Division of Pediatric Nephrology, Kidney Institute, Medanta, The Medicity, Gurgaon, Haryana, India, 122001 Phone: 0124–4141414 Website:��www.pediatricnephrologyindia.com

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[dailyupdatednews]

Nephrotic Syndrome in children is a kidney disorder that can have a variety of causes and symptoms. In children, the most prevalent reason is idiopathic, which implies that the exact cause is unknown. It can, however, be linked to other health conditions such as infections, drugs, or underlying kidney disease. In children, there are two types of Nephrotic Syndrome in children: minimal change disease and focal segmental glomerulosclerosis (FSGS). FSGS, on the other hand, is a more complex disorder for which treatment may be less effective. Understanding the precise cause and kind is critical for accurate diagnosis and targeted therapy, which may include medications or dietary changes. 

[nephorology]

Nephrotic syndrome treatment

Nephrotic syndrome is a kidney disorder characterized by increased protein levels in the urine, low blood protein levels, high cholesterol levels, and swelling (edema) in various parts of the body. The treatment of nephrotic syndrome aims to reduce proteinuria, manage symptoms, and prevent complications. Here are common treatment approaches:

Medications:

Corticosteroids: The first-line treatment for nephrotic syndrome is usually corticosteroids, such as prednisone. They help reduce inflammation in the kidneys and decrease protein leakage into the urine. A high dose may be prescribed initially, followed by a gradually decreasing maintenance dose.

Immunosuppressive drugs: If corticosteroids alone are ineffective or not well-tolerated, additional immunosuppressive medications like cyclophosphamide, mycophenolate mofetil, or rituximab may be prescribed to further suppress the immune system and reduce proteinuria.

Diuretics: Diuretic medications like furosemide or spironolactone may be used to manage edema by increasing urine output and reducing fluid retention.

Dietary and lifestyle modifications:

Sodium restriction: Limiting sodium intake can help manage edema by reducing fluid retention. This often involves avoiding processed foods and adding less salt to meals.

Low-fat, low-cholesterol diet: A diet low in saturated fats and cholesterol may be recommended to control high cholesterol levels often seen in nephrotic syndrome.

Adequate protein intake: In some cases, protein intake may need to be adjusted to ensure a balance between maintaining protein levels and minimizing proteinuria. This is best determined by a healthcare professional or registered dietitian.

Blood pressure control:

Angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs): These medications are often prescribed to control blood pressure and reduce proteinuria in nephrotic syndrome.

Management of complications:

Blood clot prevention: Nephrotic syndrome increases the risk of blood clots. Medications like anticoagulants (blood thinners) may be prescribed to prevent clot formation.

Vaccinations: It is important for individuals with nephrotic syndrome to stay up to date with vaccinations, particularly for pneumococcal infections and influenza, as they are more susceptible to infections.

Regular follow-up appointments with a healthcare provider are essential to monitor the response to treatment, adjust medication dosages, and address any emerging complications. In some cases, if the underlying cause of nephrotic syndrome is a specific kidney disease, additional treatments such as immunosuppressive therapies or plasmapheresis may be considered.

[biology-geology-beaches-india]

The Research Notebooks of Satyendra Sunkavally, page 37.

[ayurvedayogashram]

In this article, we will explore the various Ayurvedic Nephrotic Syndrome treatment and their effectiveness. We will also discuss how these cures work.

[bestpediatricnephrologistindelhi]

Best Pediatric Nephrologist in Delhi

Child Kidney Specialist in India

A Glimpse On Chronic Kidney Disease

CKD (chronic kidney disease) is a lifelong condition in which the kidney function slowly declines over many years. It is common in adults but extremely rare in children. It can be caused by a number of conditions affecting the kidney and can present at birth or later on during childhood. All kidney conditions do not cause CKD and all kids with CKD do not always progress to the end stage. It is a complicated disease with a wide spectrum from which full recovery is not possible but timely specialist care can help your child live a long, healthy and wholesome life.

How Severe Is My Child’s Disease?

CKD is divided into 5 stages based on GFR [glomerular filtration rate- tells how well the tiny filters (glomeruli) inside your child’s kidney are cleaning the blood].

How Would My Child Be Treated?

Your child will require specialized medical care from a pediatric nephrologist. It is important that you regularly visit the clinic for follow-up appointments even if your child feels well. At each of these visits, the growth(height,weight) and kidney function of your child would be monitored to avoid any future complications. The medical treatment aims at-

Reducing blood pressure [by low salt diet and medicines]

Slowing protein loss in the urine [by medicines like ACE-I(angiotensin converting enzyme inhibitor) or ARB(angiotensin receptor blocker)]

Avoiding bone disease [by calcium and vitamin D supplements] 

Controlling anemia [by erythropoietin supplements or blood transfusion]

Healthful living-

Ensure that your child eats at least five servings of fruits and vegetables a day. Cut down on his/her sugar and fat intake.

Get him/her plenty of exercise.

Avoid taking common medicines like ibuprofen/diclofenac without higher supervision as they cause further kidney damage.

Many children with progressive disease who develop ESRD would ultimately need dialysis, which uses special equipment to remove waste products and extra water from their body. The best treatment is a kidney transplant, in which a healthy kidney from another person is transplanted into the child. After a successful kidney transplant, the child can live a healthy life, but will need to take medicines to look after the new kidney.

What To Anticipate About My Kid’s Future?

CKD can take a heavy emotional toll not just on the kid but the entire household. Speaking with families of other children with CKD can be a huge support. Your child will need to take care of his or her health throughout life. As an adult, he/she will be supported by a new team. Due to the current medical advancements, children with CKD can reach their adulthood with better kidney outcomes. They should be encouraged to live a full and fulfilling life, pursue higher education, work and have a family.For any queries or concerns, please visit this website/contact Dr. Sethi today.

TAG : Child Kidney Specialist in Delhi, Child Kidney Doctor in Gurgaon, Pediatric Nephrology India

[pediatric-nephrologist]

Today our group has published a review on ‘Anti Factor H Antibodies in aHUS’ in ‘Frontiers in Immunology’ today. Antibodies to Factor H is the most common cause of aHUS in children in our country and we have published multiple research papers on this in last 2 decades.

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Disabilities that need more examples:

PCOS

Epilepsy

Arhinia

Parkinson’s

Sjögren syndrome

Phantom pains

Cataract

Genu Recurvatum

Amelia

Glaucoma

Coma

Chronic pain

Diabetes

Nephritis, Nephrotic Syndrome, and Nephrosis

Feel free to add more to the list.

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[heardatmedschool]

Doctor: Do you have any questions about the exam?

Student: What was the answer of the nephritic syndrome question? We discussed among ourselves and none of the alternatives made any sense.

Doctor: Crap, it was supposed to be about nephrotic.

[nuhospitals24]

Haemodialysis | NU Hospitals

Haemodialysis is a process that balances blood chemistry and filters wastes and fluid from the blood. For haemodialysis, two needles are inserted into the patient’s arm.