#Nasolabial cyst
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brucekee135711 · 10 months ago
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As an oral surgeon, do you remember the development of the pre-maxilla?
The premaxilla is a crucial component of the upper jaw during the embryonic stage of development. It develops from the fused lower portions of the medial nasal processes and carries two central and two lateral incisors. The premaxilla stabilizes the facial skeleton and is comparable to the keystone of a masonry arch. Defective development of the premaxilla can lead to malformations of the mouth…
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The Pouched Proboscis - Nasolabial Cyst- Crimson Publishers
The Pouched Proboscis - Nasolabial Cyst  by Anubha Bajaj in Integrative Journal of Conference Proceedings
Nasolabial cyst is an exceptional, non-odontogenic, developmental, maxillofacial cyst which arises between nasal vestibule and upper lip. The extra-osseous nasolabial cyst was initially scripted by Zuckerkandl in 1882. The soft tissue cyst is commonly discerned beneath alae nasi and is additionally designated as nasoalveolar cyst or Klestadt cyst. However, nasolabial cyst is confined to the soft tissue, in contrast to a nasoalveolar cyst which characteristically engenders a maxillary bone defect. The infrequently discerned nasolabial cyst can be misinterpreted and subjected to unsatisfactory therapy. Clinical discernment may be appropriate and adequate on account of characteristic location and clinical representation.
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For more articles in our journal click on:    https://crimsonpublishers.com/icp/index.php
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lanara-julliet · 3 years ago
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What Are The Types Of Dermal Fillers?
As many people are sourcing more Holy Grail to maintain the fountain of youth, there are now more options without undergoing surgical procedures. One of which is the FDA-approved filler name dermal filler that has been used by 1 million men and women annually to revitalize their faces and improve the natural facial symmetry with immediate wrinkle improvement. Dermal fillers restore volume, correct facial lines and wrinkles, even add a little plump to the lips. Indeed, the loss of volume and fullness in faces has been the most compelling evidence with age that so many people are looking to fight with as the facial muscles work closer to the skin surface, which is why smile lines and crow’s feet become more apparent. Additionally, the facial skin also stretches a bit, adding to this loss of facial volume. Other factors which may also affect the facial skin include sun exposure, heredity, and lifestyle.
What Are The Types Of Dermal Fillers?
Generally, the most common dermal filler used today is hyaluronic acid, but everyone must know that it has more types. Knowing the best dermal fillers that work per individual is the same as being thorough in terms of understanding the facial anatomy and familiarity with the variety of available fillers and their respective injection techniques.
Calcium hydroxylapatite- is a natural mineral-like compound which is found in human bones, which is highly used to intensify the fullness of the cheeks and other facial contours, marionette lines and frown lines, moderate-to-severe creases such as nasolabial folds, and improve volume in areas of facial wasting, such as HIV-positive people taking certain medications.
Hyaluronic acid. It’s an injection used to improve the skin’s contour and reduce depressions due to scars, injury, or lines. The product can potentially dramatically improve cheek depressions, crow’s feet at the corner of the eyes, acne scars, nasolabial furrows, marionette lines at the corners of the mouth, burns, and acne and wound scars, smoker’s lines, redefining lip border. These worry lines run across your forehead, vertical lines on the mouth, some facial scars.
Polyalkylimide. It’s a semi-permanent dermal filler and is highly used by cosmetic surgeons to plump thin lips, enhance cheekbones and the jawline, treat deeper wrinkles such as nasolabial folds or depressed scars and substitute facial volume loss that comes with age, and treat facial wasting from HIV medications.
Polylactic acid. It is a synthetic dermal filler injected into the face, causing the body’s collagen production. It is known as a stimulator that is a non-toxic, biodegradable substance that has been used as a suture material for more than 40 years and works particularly well in the lower half of the face and is highly sed to fill the lines caused by laughing, plump thin lips, and treat deep nasolabial folds.
Are Dermal Fillers Safe?
Its safety would rely on the correct physician to perform the dermal filler procedure. The medical professional should undergo training and certification to ensure that the patient receives care from a board-certified, experienced dermatologist or cosmetic surgeon. Its purpose should be to achieve natural, beautiful, and safe results. Moreover, the medical professional will evaluate any specific areas of concern, understand the patient’s expectation of the procedure, and assess it before, during, and after the treatment to ensure the best cosmetic outcome. There might be some discomfort during or after the injections, bruising, and swelling. Still, it is also advisable for patients not to schedule their procedure before a big social event as they might get bruises after their injections.
Thus, it is also advisable to report any following conditions or symptoms before the procedure to the medical professional.
Skin is inflamed or infected.
Cysts, pimples, rashes, or hive or infection,
Bleeding disorder.
Severe allergies or acute allergic reactions
Allergic to collagen or eggs.
Allergic to animal products.
Allergic to local anesthetics such as lidocaine.
Allergic to bacteria.
When considering hand augmentation, you have joint, tendon, or blood vessel disease affecting the hand.
How Long Do The Results Last?
There are fillers that can only last for six months before needing a top-up, while others may last for a few years. Of course, dermal fillers will last depending on the product, the area of treatment, and the patient. Correspondingly, noninvasive procedures such as fillers are attractive because they are quick and have minimal downtime. In fact, the denser the product and the more deeply the injection, the result may last longer, even though this is not a hard and fast rule. Generally, the amount and techniques necessary to ensure optimal results will depend on how many treatments the medical professional suggests to maintain its effect. More importantly, the patient may also influence the longevity of the dermal filler by avoiding sun exposure due to harmful UV rays, avoiding smoking, and not drinking any alcoholic beverages.
Which Provider To Choose For Filler Treatments?
When choosing a provider for injectable treatments like dermal fillers, entrust the decision with the higher level of scrutiny one must decide in a surgical procedure. At Detroit Aesthetics Company, their team of expert injectors utilizes products from many of the leading aesthetics companies, including:
Galderma- Restylane Family of Fillers is ideal for those with allergy concerns and an excellent filler for tear troughs with excellent results filling areas around the eyes.
Allergan- Juvederm Family of Fillers is excellent for contouring the cheeks, smoothing lines, and plumping the lips.
Revanesse Versa is a hyaluronic acid filler with FDA approval with immediate anti-aging properties and results for 12 months.
Merz Aesthetics- Radiesse and Belotero are injectables that provide optimal smoothing and filling results. Radiesse provides biostimulant properties and offers anti-aging qualities to the hands as the face and neck.
Revance- RHA Dermal Fillers provides an arsenal of RHA and hyaluronic acid fillers indicated for the deeper skin layers to give a more thorough but natural-looking rejuvenation.
Much like an artist chooses the best paint for their artwork, their team of expert injectors will choose the best filler to meet your dynamic needs to achieve your most beautiful results.
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lupine-publishers-sjo · 4 years ago
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Lupine Publishers | Sinonasal Surgeries in a Tertiary Health Care Institution in a Developing Country, Nigeria
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Lupine Publishers | Journal of Otolaryngology
Abstract
Background: Sinonasal diseases usually required surgical management. There is increasing cases of poorly treatment by nonspecialist. This study aimed at determining sociodemographic features, indications, complication and outcome of sinonasal surgeries
Materials and methods: This was a retrospective study of patients that had sinonasal procedures in our tertiary health care facility. The data collected were collated and analyzed using Statistical Package for Social Sciences (SPSS) version 18.0.
Results: The proportion of sinonasal procedures among the patients was 31.6%. There were 58.8% males with male to female ratio of 1.5:1 Major presenting complaints was 57.3% nasal blockage and 52.8% catarrh/epistaxis. Common clinical findings were rhinorrhea and reduced nasal patency in 69.4% and 48.8% respectively. Sinonasal procedures in unilateral nasal cavity was 52.2% while right nasal cavity occurred in 29.6%. Outpatient clinic procedures was 66.7%, elective procedures accounted for 60.5% and major procedures accounted for 29.3%. masses is the commonest CT Scan findings in 20.3% followed by sinuses in 15.6%. Main diagnosis was 39.9% rhinosinusitis, 38.3% foreign body impaction and 10.8% nasal polyps. Common sinonasal procedures were 38.3% nasal foreign body removal, 10.8% polypectomy, 9.8% antral washout and 9.3% nasal packing. Main complication of sinonasal procedures were wound infection in 2.9% and recurrence in 2.6%. There was 76.2% patient’s satisfaction with the sinonasal surgeries.
Conclusion:Sinonasal surgery is common in all age group. Presentation were most late, complicated and advanced. It mostly presented as clinic and elective procedures in this study.
Keywords:Rhinologist; sinonasal surgeries; nasal diseases; sino nasal diseases
Introduction
Sino nasal surgery is an art of surgical treatment of the nose and para-nasal sinuses pathology by either otorhinolaryngologic or Rhinologist [1,2]. Sino nasal diseases are on the increase due increase in industrialisation and technology [3-5]. There is also increase in sociomedical interaction and cosmetic consciousness about nose worldwide [5]. All these has led to growing rhinology subspecialty demands. Nose occupied the strategic position in the middle third of the face [6-8]. It is the outermost and uppermost conduit of the respiratory tract and prone to all forms of environmental hazard. This ranges from congenital to acquired diseases [3,4]. Various types of acquired nasal diseases includes traumatic, inflammatory, neoplastic, metabolic and systemic diseases with nasal manifestation [3,4]. Sinonasal diseases may also be primary or secondary to diseases from other head and neck organs which includes eye/orbit, dental apparatus, brain, cranial nerves and other intracranial structures [9-11]. These are managed by different forms of surgical approach and adjunct medical treatment. Clinical presentation of sinonasal disorders and other related diseases such as rhinosinusitis, sin nasal tumour, nasal polyps, dental diseases, lacrimal disorders, pituitary tumours, sin nasal cerebrospinal fluid rhinorrhea, and anterior skull base tumours presented to family physician, casualty officers, neurosurgeons, and ophthalmologists and subsequently referred to otorhinolaryngologic [12-14]. Pattern of clinical features of sinonasal diseases are nasal discharge, nasal blockage, nasal mass, bout of sneezing, headache, fever and facial asymmetry [13,14]. Other related symptoms depends on the primary source of sinonasal diseases which includes ocular symptoms, orodental symptoms and central nervous system symptoms. Radiological imaging inform of computerised tomography scan is required to rule out the extent of the tumour and bony destruction. Sinonasal endoscopy for diagnosis and determined to tumour origin with its extent is also an important investigation.
Majority of sinonasal surgery may be done in by otorhinolaryngologist or rhinologist alone or in team in collaboration with ophthalmologist, neurosurgeon, plastic and oral and maxillofacial surgeon. The approaches may either intranasal and extra nasal depending on the site and extent of the pathology [15-16]. Non-invasive procedures such as functional endoscopic sinus surgery is a newer surgical technique [2,9]. It is not a common surgical intervention in low income country like other surgical procedures but a commonplace in the developed countries. Sinonasal surgery in most developing countries has been hampered by the dearth of otorhinolaryngologic and rhinologist. There is also inadequacy of proper diagnostic tools and therapeutic facilities in developing countries compare to developed world. There is a paucity of publication documents on the pattern of sinonasal surgeries in developing countries. The knowledge from the documentation of sinonasal surgeries in our environment will help draw attention of the appropriate authorities to the challenges in the surgical practice. This will serve as bases to develop and form policy on sinonasal surgery improvement. This study aimed determining sociodemographic features, types, indications, limitation, complication and outcome of sinonasal surgeries in a tertiary health care institution of a developing country.
Materials and Methods
This was a retrospective study of all patients that had sinonasal surgeries done in Ear, Nose and Throat department of Ekiti state university teaching hospital Ado Ekiti, Nigeria. The study was carried out over a period five years (between October 2014 to September 2019). Data for this study was obtained from the hospital medical record department, ENT clinic operation booking register for both minor and major surgery and theatre operation register. The case notes of all the eligible patients were retrieved from the medical record department. Detailed data on sociodemographic features were obtained from the patient’s case note. Data of patient on clinical features, diagnosis, and indication for procedures, and type of procedures, complications, and patient’s satisfaction with the outcome of the procedures were obtained and documented. Inclusion criteria were all the patients that had sinonasal procedures in the department during the study period. Exclusion criteria were those patients who were not operated. Also, patients with incomplete clinical data on this study or those with missing case notes. All the obtained data were collated, documented and statistically analysed using SPSS version 18.0. The data were then expressed by descriptive statistics in frequency tables, percentage, bar chart and pie chart.
Results
The total number of patients seen during the period of study was 7,916 out of which a total of 1965 (24.8%) had sinonasal diseases and 621 had sinonasal procedures done given prevalence of 31.6%. In this study, the peak age groups were at the extreme ages of (1-10) years with highest number of procedures in 218 (35.1%). This is illustrated in Table 1. Gender distribution were 365 (58.8%) males and 256 (41.2%) females with male to female ratio of 1.5:1. Urban dwellers 341 (54.9%) were commoner than rural dwellers 280 (45.1%). Christians faith occurred in 547 (88.1%) while Muslims faith occurred in 74 (11.9%). Main patient/parent education level were 182 (29.3%) primary and 173 (27.9%) secondary. Parent/ patient occupation distribution were mainly student/apprentice, civil servants and business in 277 (44.6%), 138 (22.2%) and 89 (14.3%) respectively. This is showed in Table 2. Major presenting complaints was nasal blockage in 356 (57.3%) followed by catarrh/ epistaxis, objects in the nose and bout of sneezing in 328 (52.8%), 246 (39.6%) and 228 (36.7%). Common clinical findings were rhinorrhea, reduced nasal patency, foreign body impaction and sinonasal masses in 431 (69.4%), 303 (48.8%), 238 (38.3%) and 100 (16.1%) respectively. As demonstrated in Table 3.
Table 1:  Age group distribution of the patients.
Table 2:  Sociodemographic features of the patients.
Table 3:  Main clinical features among patients
Sinonasal procedures was commoner in unilateral nasal cavity in 324 (52.2%) than bilateral nasal cavity in 297 (47.8%). Right nasal cavity and left nasal cavity procedures occurred in 184 (29.6%) and 140 (22.5%) respectively. As illustrated in Figure 1. Majority of the procedures in 414 (66.7%) were performed in the outpatient clinic and minority in 207 (33.3%) were performed in the theatre. Theatre procedures were classified into minor, intermediate and major procedures which accounted for 8 (1.3%), 17 (2.7%) and 182 (29.3%) respectively. All sinonasal procedures were divided into elective and emergency procedures which accounted for 376 (60.5%) and 245 (39.5%) respectively. This is demonstrated in Table 4. Intranasal masses is the commonest CT Scan findings in 126 (20.3%). CT Scan findings in the sinuses accounted for 97 (15.6%) with maxillary and ethmoid sinuses accounted for 52 (8.4%) and 39 (6.3%) respectively. Common extension of the sinonasal pathology in this study were orbital extension and intracranial extension in 59 (9.5%) and 21 (3.4%) respectively. This is illustrated in (Figure 2). Main diagnosis and indication for sinonasal procedures in this study were rhinosinusitis in 248 (39.9%), nasal polyps in 67 (10.8%), sinonasal injuries in 29 (4.7%) and foreign body impaction in 238 (38.3%). Less common diagnosis and indications were nasolabial cyst, frontoethmoidal mucocele, and fungal mass in 2 (0.3%), 3 (0.5%) and 4 (0.6%) respectively. This is showed in (Table 5). Commonest sinonasal interventional procedures in patients with sinonasal diseases in this study was 238 (38.3%) foreign body removal from the nose. Removal without anaesthesia and under general anaesthesia were 226 (36.4%) and 12 (1.9%) respectively. Other main sinonasal surgeries were polypectomy, antral washout (lavage), nasal packing, partial turbinectomy, nasal toileting/clearance and intranasal antrostomy in 67 (10.8%), 61 (9.8%), 58 (9.3%), 51 (8.2%), 46 (7.4%) and 44 (7.1%) respectively. Intranasal polypectomy occurred in 59 (9.5%) while extranasal polypectomy (Caldwell Luc procedures) occurred in 8 (1.3%). Less common sinonasal procedures were 3 (0.5%) rhinoplasty, 3 (0.5%) nasal cautherization, 3 (0.5%) reduction of nasal bone fracture and 4 (0.5%) suturing of lacerations. This is revealed in Table 6. Complications occurred in sinonasal surgeries in 64 (10.3%). Main complication of sinonasal procedures in this study was wound infection in 18 (2.9%). Other documented complication were recurrence in 16 (2.6%) and epistaxis in 14 (2.3%). Uncommon complication sin this study included septal perforation and adhesion in 1 (0.2%) and 2 (0.3%) respectively. This is shown in Figure 3. In this study, 65 (10.5%) of the patients were referred to other center for further investigation and treatment. Main limitation and indication for referral were surgical facilities, chemoradiotherapy and diagnostic equipment in 5 (0.8%), 6 (1.0%) and 41 (6.6%) respectively. Endoscopic sinus surgery was responsible for 4 (0.6%) referral. Patient financial constraints in 28 (4.5%) leads to delayed surgery. This is illustrated in Figure 4. In this study, 473 (76.2%) of the patients and their parents were satisfied with the sinonasal surgeries. Revision sinonasal surgeries were offered in 4 (0.6%). We recorded 14 (2.3%) patients’ loss to follow up. Surgical failure was noted in 12 (1.9%) patients. Patient in 6 (0.6%) was referral for sinonasal surgery in other center. Referral in 3 (0.5%) was for family support in other center. This is illustrated in Table 6.
Figure 1: Coronal CT imaging. In hypotympanun the foreign body is visualized (A).
Figure 2: CT Scan findings among patients.
Figure 3: Complications among the patients.
Figure 4: Limitation and indication for referral among the patients.
Table 4:  Main clinical features among patients.
Table 5:  Diagnosis and indications for surgeries among patients.
Table 6:  Procedures/Surgeries among patients.
Discussion
Sinonasal diseases is very common among otorhinolaryngology, head and neck diseases that visited our department. Most of these diseases presented late, untreated, poorly treated and usually complicated at presentation. There was high prevalence of surgical interventions due to the disease’s stages at presentation. In this study, sociodemographic features affected the pattern of sinonasal surgeries. The procedures were commonest in children and this is associated with high rate of infection, immunity, injuries and insertion of infected objects into head and neck orifices. Sinonasal surgeries are commoner in male than female (Figure 5). This may be due to high rate of infection and outdoor activities such as trauma and hazard in offices in male. Also, high rate of smoking and snuff in male. Due to availability, accessibility, affordability and better informed, urban dwellers had more sinonasal procedures than rural dwellers in this study [17].
Figure 5: Outcome of the surgeries/procedures among patients.
Sinonasal diseases in this study presented mainly with nasal blockage, objects in the nose, catarrh/epistaxis and bout of sneezing.18 Most of the patients presented late or with complicated cases. All sinonasal symptoms were assumed to be flu which is selftreated. Most patients or parents wrongly believe it is a household disease, self-limiting, treated at home and does not worth hospital consultation. Common clinical findings in our study were anterior rhinorrhea, reduced nasal patency, nasal foreign body impaction and sinonasal masses [19,20]. Unilateral sinonasal disorder were commoner than bilateral this may be because of the aetiology origins of the pathology. Likewise, right sinonasal conditions were commoner than left. Most patients are right handedness with easy picking of right nose. Most patients sleep on the right side with poor venous drainage and accumulation and gravitation of infectious mucous on right nose. Main sinonasal diseases in this study were rhinosinusitis, foreign body impaction and nasal polyps. In this study, sinonasal diseases are not limited to the nose and sinuses alone irrespective of the aetiopathogenesis. Radiologic imaging is essential to rule out extent of the pathology and adequate preparation for the surgery. Commonest extension was orbit followed by intracranial and palatal extension [21]. Sinonasal Surgeries usually required teamwork with ophthalmologist, neurosurgeon and oral and maxillofacial surgeon depending on the extent of the pathology. Chronic rhinosinusitis with major nasal obstructions in adult is usually secondary to enlarge and obstructive inferior turbinate. In this study, clinic procedures were commoner than theatre surgeries this may be due to inclusion of all cases. There was preponderance of emergency surgery over elective procedures because of self-medications, untrained hand interventions and presentation of complicated cases to our department. Among the theatre cases, commonest surgery was major surgery followed by intermediate and minor surgeries. This is because most of the cases were advanced and extranasal extensions. Commonest procedures were nasal foreign body removal of which majority were performed in outpatient clinic and minority in theatre under general anaesthesia. Polypectomy were performed under general anaesthesia because they are advanced with Intranasal approach commoner than extranasal approach such as Caldwell Luc procedures [22].
Antral washout mainly bilateral was carried out on patients with mucopurulent collection in the maxillary sinuses. Nasal packing was carried out among patients seen with epistaxis mainly secondary to inflammation and trauma. Anterior nasal packing was commoner than posterior packing where chemical cautherization was performed where bleeding point was visualized. Cases of rhinosinusitis were further treated with partial turbinectomy in obstructive turbinate and Intranasal antrostomy to aid antral drainage and ventilation. Nasal toileting/clearance were performed in outpatient clinic among patients mucopurulent and clotted blood in the nasal cavity. Other approach to sinonasal masses in our study was external frontoethmoidectomy or excisional biopsy for histological diagnosis. Depending on the type and form sinonasal injuries surgical interventions in this study were suturing, wound dressing, reduction of nasal bone fracture and rhinoplasty. Nasal septal abscess was drained. No functional endoscopic sinus surgery was performed in our center because endoscope, forceps and other accessories are yet to be procured by hospital management [23]. Associated complications of our sinonasal surgeries were surgical site infection which were treated by antibiotics institutions [24,25]. Recurrent tumour in malignancy were referred for chemoradiation therapy. Immediate reactionary haemorrhage which was treated with nasal packing. Temporary loss of olfactory from clotted blood and oedema. Adhesion was released and nasal patency was restored. The septal perforation was asymptomatic, not noticed by patient and being followed up in our out patients clinic. Patients that required are CT Scan referred. Patients with financial constraints were assisted in sourcing for funds and surgery was eventually performed [26]. Patients that required further surgery and chemoradiotherapy were referred to centers where they were available. Majority of the patients were satisfied with the offered procedures. However few cases of revision surgery, referral, loss to followed up and Surgical failure were recorded in this study. This may be due to lower number of major sinonasal surgeries in this study.
Conclusion
Sinonasal surgeries are still not fully practice despite all the cases and Practicing rhinologist/ otorhinolaryngologist. This is due to limited equipment and adequate funding by policy makers. Provision of adequate surgical facilities will tremendously reduce referral cases and encourage surgical tourism in our center and other developing country.
Funding
There was no financial support. It is a self sponsored research study.
Competing interests
All the authors declare that there were no competing interests.
Acknowledgement
The authors are most grateful to Ekiti state university teaching hospital, the staff and all the patients who participated in this study.
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cirugiaoraleimplantologia · 8 years ago
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#Repost @maxillofacialtips with @repostapp ・・・ 🇺🇸Intraoral sublabial resection of a nasolabial cyst. Case conducted by our graduate students. Oral and Maxillofacial Surgery Program of PUC Minas. ☝️ Nasolabial cysts are rare benign nonodontogenic masses that arise in the nasal alar region. These cysts account for 0.7% of all nonodontogenic #cysts. They are often located submucosally in the anterior nasal floor and can elevate and medially displace the inferior turbinate. This entity was first studied by Emile Zucker-kandl in 1882. Walter Klestadt, whose research on #nasolabial cysts in 1953 led these cysts to be also referred to as Klestadt’s cyst. Intra-oral sublabial resection is considered the standard treatment modality. -------------- 🇧🇷 Ressecção de cisto nasolabial por acesso sublabial. Caso conduzido por nossos alunos de Pós-Graduação. Aperfeiçoamento em Cirurgia Bucomaxilofacial da PUC Minas. ☝️️ Os cistos nasolabiais são lesões não odontogênicas raras que surgem na região alar. Estes cistos representam 0,7% de todos os cistos não odontogênicos. São frequentemente encontrados na região submucosa do assoalho nasal anterior e podem elevar e deslocar a asa do nariz. Esta patologia foi primeiramente descrita por Emile Zucker-kandl em 1882. Walter Klestadt, realizou um estudo sobre a origem desses cistos em 1953. Após esse estudo o cisto também ficou conhecido como cisto de Klestadt’s. A ressecção por acesso sublabial é considerado o tratamento padrão. #maxillofacialtips #maxillofacial #maxillofacialsurgery #odontologia #odonto #odontoporamor #ctbmf #omfs #oralpathology #oralmedicine #medicine #pathology #surgeon #surgery #surgeryday
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elenuniverse-blog1 · 7 years ago
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Beauty secrets quotes, facial rejuvenation ottawa
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Facelift Cosmetology
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ratemylawnandgarden · 7 years ago
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By Using Laser Treatment, A Dermatologist May Not Only Care For The Cyst, But In Addition Elimina …
A seasoned dermatologist is able to help you treat these cysts in an effective way. Some dermatologists concentrate on particular areas in dermatology and you probably’re going to want to see one which specializes in your concern. If you’re on the lookout for the premiere dermatologist within the space, you may have arrived at the correct place. It’s used and recommended just for nasolabial wrinkles and folds.
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