#NYU Langone Health School of Medicine

[informationhospital]

NYU Langone Health Hospitals, Doctors, Appointment, Appointment, Health School of Medicine

New Post has been published on https://www.informationhospital.com/nyu-langone-health-hospitals-doctors-appointment-appointment-health-school-of-medicine/

NYU Langone Health Hospitals, Doctors, Appointment, Appointment, Health School of Medicine

NYU Langone Health Hospitals

Nestled in the dynamic landscape of New York City, NYU Langone Health Hospitals have carved out a reputation that resonates far beyond the boundaries of the metropolis. As vital components of the revered NYU Langone Health system, these hospitals exemplify the pinnacle of medical care, research, and education, asserting their position among the world’s leading healthcare institutions.

From their inception, NYU Langone Health Hospitals have been guided by a vision to serve the diverse and complex needs of their community. New York, with its melting pot of cultures, presents a unique set of healthcare challenges. Yet, these hospitals have consistently risen to the occasion, innovating and adapting to ensure that every individual, regardless of their background, has access to top-tier medical care.

A significant aspect of NYU Langone Health Hospitals’ acclaim comes from its unwavering commitment to research. The hospitals house state-of-the-art research facilities that act as hubs of innovation. Scientists and researchers at these institutions are at the forefront of groundbreaking studies, often transcending traditional boundaries to foster interdisciplinary collaborations. From pioneering research in genetics to innovations in surgical techniques, the impact of their work is felt globally, changing lives and shaping the future of medicine.

Furthermore, NYU Langone Health Hospitals take immense pride in their role as educators. As centers of academic excellence, they attract some of the brightest minds from across the globe, eager to learn from the best in the field. The hospitals offer a myriad of programs, training courses, and internships that are meticulously designed to ensure that the next generation of healthcare professionals is well-equipped to tackle future challenges. Their alumni network, dotted across the world, stands testament to the quality of education imparted.

But beyond the cutting-edge treatments, groundbreaking research, and world-class education, what truly sets NYU Langone Health Hospitals apart is their philosophy towards healthcare. They recognize that healing is as much an art as it is a science. Every patient is treated with compassion, dignity, and respect. The patient-centric approach ensures that care is holistic, addressing not just physical ailments but also catering to emotional and psychological well-being.

In conclusion, NYU Langone Health Hospitals are more than just medical institutions. They are symbols of hope, resilience, and human endeavor. In the ever-evolving realm of healthcare, they continue to set benchmarks, embodying the perfect blend of tradition and innovation. Whether you’re a patient seeking world-class care, a budding medical professional in pursuit of excellence, or a researcher aiming to make a mark, NYU Langone Health Hospitals offer a sanctuary where dreams are realized and lives are transformed.

NYU Langone Health Doctors

NYU Langone Health stands as one of the nation’s premier academic medical centers, a reputation built not just on cutting-edge facilities or advanced technologies, but on the backbone of its clinical excellence: the doctors. The physicians at NYU Langone Health hail from a diverse tapestry of backgrounds, cultures, and specialties, yet they share a unified mission – to provide exceptional, patient-centered care.

Distinguished in their respective fields, many of these doctors are recognized both nationally and internationally for their contributions to medicine. Whether they are pioneering new surgical techniques, conducting transformative research, or shaping the next generation of doctors through education, their impact reverberates throughout the global medical community. Every day, they are at the forefront, pushing the boundaries of what’s possible in medicine, seeking better answers, and driving innovation.

However, beyond their accolades and achievements lies an even more crucial element that defines the essence of an NYU Langone Health doctor: compassion. In every interaction, they emphasize a patient-first approach, understanding that behind every diagnosis is a human story. They listen, empathize, and build trust, ensuring that patients and their families feel seen, heard, and valued. This deep commitment to human connection is what often sets them apart, transforming routine medical care into a healing journey.

Another defining aspect of these doctors is their dedication to continuous learning. Medicine is an ever-evolving field, with new discoveries and advancements emerging frequently. The physicians at NYU Langone Health are not just passive observers of these changes; they are active participants, often leading the charge in groundbreaking research and integrating the latest findings into their practice. This commitment to staying updated ensures that patients always have access to the most advanced treatments available.

Collaboration is also a cornerstone of their approach. Recognizing that complex health challenges often require multifaceted solutions, doctors frequently collaborate across disciplines. This interdisciplinary approach ensures that patients benefit from a broad spectrum of expertise and experience, leading to more holistic care.

In addition to their clinical roles, many of these physicians also serve as educators, mentoring the next generation of medical professionals. Their teachings ensure that the legacy of excellence, compassion, and innovation at NYU Langone Health continues, further strengthening the institution’s future.

In conclusion, the doctors at NYU Langone Health are more than just healthcare providers; they are visionaries, leaders, researchers, educators, and most importantly, caregivers. Their dedication, expertise, and humanity are what truly make NYU Langone Health a beacon of medical excellence. Whether a patient is seeking routine care or facing a complex medical challenge, they can trust that they are in the capable hands of some of the world’s finest physicians.

NYU Langone Health Appointment

The Importance of Scheduling at NYU Langone Health

The world of modern healthcare is ever-evolving, with the incorporation of new technologies, advanced treatment modalities, and a patient-centric approach. Amidst this transformation, the significance of an organized and efficient appointment system cannot be overstated. At NYU Langone Health, a renowned institution in the realm of healthcare, the appointment process takes center stage in ensuring patients receive the care they deserve in a timely manner.

A Beacon of Excellence in Healthcare

Located in the heart of New York City, NYU Langone Health stands as a beacon of medical excellence. The institution boasts a rich history that spans over a century, marking several milestones in medical innovation and patient care. Today, it serves as a multidisciplinary hub, catering to diverse medical needs ranging from routine screenings to complex surgical procedures. But at the heart of this sprawling healthcare empire lies a simple, yet crucial aspect: patient appointments.

Efficiency Meets Compassion

Every patient’s journey at NYU Langone Health begins with scheduling an appointment. Understanding the anxieties and uncertainties that can surround medical consultations, the institution has made significant strides in ensuring its appointment system is as efficient as it is compassionate. New patients, especially, might feel overwhelmed by the plethora of medical specialties and services. Here, the hospital’s dedicated scheduling team steps in, guiding patients through the process, helping them navigate the system, and ensuring they connect with the right specialist for their unique needs.

Advanced Digital Integration

In today’s digital age, the integration of technology into the appointment system has proven beneficial for both patients and healthcare providers. NYU Langone Health has embraced this shift with open arms, offering a seamless online portal where patients can not only schedule appointments but also access their medical records, communicate with their doctors, and receive timely reminders. This digital approach reduces administrative burdens and minimizes the chances of scheduling errors, ensuring a smoother healthcare experience for all.

A Commitment to Timely Care

While the importance of an organized scheduling system is clear, the ultimate goal remains to provide timely care. NYU Langone Health prides itself on its reduced wait times and its commitment to seeing patients as close to their scheduled times as possible. This efficiency reflects the institution’s overarching ethos: to prioritize the patient’s needs at every step.

In Conclusion

At NYU Langone Health, the emphasis on an effective appointment system stems from a deeper commitment to patient welfare and care. It’s not merely about filling slots in a calendar; it’s about ensuring that every individual receives the best possible care when they need it. As healthcare continues to evolve, institutions like NYU Langone are leading the way, showcasing how efficiency and compassion can go hand-in-hand, setting a gold standard for patient-centric care.

NYU Langone Health Address

New York City, known for its iconic skyscrapers, diverse culture, and relentless pace, is also home to some of the world’s leading medical institutions. One such beacon of medical excellence is NYU Langone Health. Situated strategically within the city’s parameters, its address serves as a beacon for those in pursuit of unparalleled medical care.

At NYU Langone Health, the address is not merely a point on a map. It symbolizes a confluence of medical innovation, research breakthroughs, and compassionate caregiving. As patients and their families navigate the intricate streets of New York, they find solace in knowing that behind the doors of this esteemed address, a team of world-class professionals is dedicated to their well-being.

The facility’s central location ensures it remains accessible to both locals and international visitors. Whether one is coming from the labyrinthine streets of Manhattan, the diverse neighborhoods of Brooklyn, or even from another country, NYU Langone Health’s address is recognized globally. Its proximity to major transportation hubs ensures that patients can reach their appointments with ease, minimizing the added stress of navigating a sprawling city.

But what makes this address truly special? Beyond its physical location, it’s the promise of what lies within. The hospital is a nexus of cutting-edge technology and human touch. State-of-the-art diagnostic machines whir beside rooms where patients and their families share intimate moments. Renowned physicians collaborate with researchers, constantly pushing the boundaries of what’s medically possible, driven by a shared mission to provide the best care.

Furthermore, the address signifies NYU Langone Health’s commitment to community outreach. Nestled in the heart of the city, it regularly hosts community events, health workshops, and educational seminars, reinforcing its role not just as a healthcare provider, but as a community partner.

For those unfamiliar with New York City, it’s worth noting the significance of such a central address. In a city where everything moves at lightning speed, the importance of accessibility cannot be overstated. Having a prominent medical facility like NYU Langone Health centrally located means that in times of emergency, critical care is but a short journey away.

However, the address also stands as a testament to the hospital’s history and its enduring commitment to excellence. Decades have passed since its inception, and through the years, the institution has grown in size, scope, and reputation. Yet, its core ethos remains unchanged: to serve, to heal, and to innovate.

In conclusion, while NYU Langone Health’s address might be a set of numbers and words on paper, its true essence is far more profound. It represents hope, dedication, and the relentless pursuit of medical excellence in the heart of one of the world’s most dynamic cities. As the cityscape of New York continues to evolve, this address remains a constant—a sanctuary of healing in the midst of urban chaos.

NYU Langone Health School of Medicine

NYU Langone Health School of Medicine: Shaping the Medical Leaders of Tomorrow

In the midst of the bustling, ever-evolving landscape of New York City, stands a pillar of medical excellence: the NYU Langone Health School of Medicine. It’s not just any educational institution; it’s a transformative hub that has, for decades, been setting benchmarks in the realm of medical education and research.

The foundation of the NYU Langone Health School of Medicine is built upon an illustrious history that traces back to its establishment. Over the years, it has garnered a reputation for being at the forefront of medical innovation. From pioneering breakthrough research studies to introducing cutting-edge medical technologies in its curriculum, the institution has always strived to stay one step ahead in the dynamic field of medicine.

Central to its success is a world-class faculty that brings together seasoned practitioners, leading researchers, and passionate educators. They not only impart knowledge but also inculcate a spirit of curiosity and critical thinking in their students. By nurturing this dual approach of theoretical knowledge and practical application, the school ensures that its graduates are not just doctors in the traditional sense but medical leaders equipped to navigate the challenges of the 21st century.

The curriculum at NYU Langone Health School of Medicine reflects its commitment to excellence. By integrating traditional medical teachings with hands-on clinical experiences from early on, students are provided with a holistic education that prepares them for real-world scenarios. Moreover, the institution’s ties with NYU Langone Health’s vast network of hospitals and clinics offer students unparalleled opportunities to learn from the best and gain invaluable experience.

Research is another cornerstone of this prestigious institution. Housing state-of-the-art labs and research facilities, the school offers a conducive environment for groundbreaking studies. Students and faculty, hand in hand, delve into intricate medical challenges, striving to unearth solutions that have the potential to revolutionize healthcare. From understanding the intricacies of genetic disorders to developing new therapeutic strategies for chronic illnesses, the breadth of research at NYU Langone Health School of Medicine is truly commendable.

However, what truly sets the institution apart is its unwavering commitment to community service. Recognizing the broader role of physicians in society, the school emphasizes the importance of empathy, compassion, and social responsibility. Students are encouraged to engage with the local community, understand their unique health challenges, and devise ways to make a tangible difference.

In conclusion, the NYU Langone Health School of Medicine is not just an institution; it’s a movement. A movement towards better healthcare, more informed doctors, and a world where medical professionals are not just healers but also innovators, researchers, and community leaders. As the school continues to blaze new trails in the world of medicine, one thing remains clear: its graduates are, and will continue to be, at the forefront of global healthcare.

https://www.informationhospital.com/nyu-langone-health-hospitals-doctors-appointment-appointment-health-school-of-medicine/

[tsmom1219]

New York City's fireworks display prompts temporary surge of air pollution

Read the full story from NYU Langone Health / NYU Grossman School of Medicine. In 2023, roughly 60,000 firework shells exploded above Manhattan’s East River as part of Macy’s Fourth of July show. The resulting air pollutant levels were many times higher in the hours after the display than those seen when smoke from a Canadian wildfire had blanketed the area a month before, according to the…

[sa7abnews]

Aspirin may be linked to lower risk of colorectal cancer, new study suggests

New Post has been published on https://sa7ab.info/2024/08/09/aspirin-may-be-linked-to-lower-risk-of-colorectal-cancer-new-study-suggests/

Aspirin may be linked to lower risk of colorectal cancer, new study suggests

Aspirin is widely known for its heart attack prevention benefits, but a new study has also linked the common drug to a reduced risk of colorectal cancer.The study analyzed data from 107,655 men and women who participated in the Nurses’ Health Study and the Health Professionals Follow-Up Study over a three-decade span. It was published in JAMA Oncology on Thursday.Researchers from Massachusetts General Hospital, Harvard Medical School and Washington University School of Medicine found that regular aspirin use was linked to a lower risk of colorectal cancer — especially for those with the unhealthiest lifestyles.DAILY ASPIRIN AFTER A HEART ATTACK CAN REDUCE THE RISK OF FUTURE EVENTS, STUDY FINDS”It shows an association between regular, low-dose aspirin use and decreased colon cancer use (close to 20%) in patients who are already at higher risk for several reasons, including smoking or poor diet,” said Dr. Marc Siegel, senior medical analyst for Fox News and clinical professor of medicine at NYU Langone Medical Center, who was not involved in the study.Criteria for determining unhealthy lifestyles included higher body mass index, heavy smoking, higher alcohol intake, lack of physical activity and poor nutrition.”We observed that participants in our study with the least healthy lifestyle had the greatest absolute benefit from aspirin use,” lead study author Daniel Sikavi, M.D., a board-certified physician at Massachusetts General Hospital, told Fox News Digital.HEART ATTACK DEATH RISK CAN DOUBLE DURING HEAT WAVES AND HIGH POLLUTION, STUDY FINDS: ‘A PERFECT STORM’”These participants had multiple risk factors that increased their overall risk of developing colorectal cancer, and our results show that aspirin can proportionally lower this markedly elevated risk.”Among patients with a healthier lifestyle, the benefit from aspirin was still evident, but less pronounced.”In the least healthy group, treating 78 patients with aspirin would prevent one case of colorectal cancer over 10 years, while it would take treating 909 patients to prevent one case in the healthiest group,” added Sikavi.As to why aspirin decreases colon cancer risk, Siegel said it is likely due to the fact that the medication acts as an anti-inflammatory, and many cancers are associated with increased inflammation.CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTERBased on the findings, the researchers suggest that health care providers consider recommending aspirin to patients with a less healthy lifestyle.”This work is an example of how we can move beyond one-size-fits-all strategies for cancer prevention by targeting effective preventive agents, such as aspirin, to the populations that are most likely to benefit,” Sikavi said.One limitation of the study was that the researchers did not systematically assess potential side effects associated with aspirin use, Sikavi noted.For more Health articles, visit www.foxnews/health”Because this was an observational study, it is possible there may have been additional factors that influenced our findings, although we rigorously accounted for a number of known risk factors for colorectal cancer,” he said.Siegel reiterated that because this is an observational study, “it is still not proof.”The American Cancer Society estimates that about 106,590 new cases of colon cancer and about 46,220 cases of rectal cancer will be diagnosed in 2024.

[dankusner]

Rare sexually transmitted ringworm found in US

Medical experts are warning doctors and the public of a rare, highly contagious fungal strain after the first report of sexually transmitted ringworm in the U.S.

According to a report released Wednesday in JAMA Dermatology, the first case involved a New York City man in his 30s who developed tinea, also known as ringworm, after having sex with men during trips to California, England and Greece.

When the man returned home, according to the case study, he developed an itchy, red rash on his groin, genitals and buttocks.

Tests confirmed he had contracted the rare, sexually transmitted fungus Trichophyton mentagrophytes type VII.

'Healthcare providers should be aware that Trichophyton mentagrophytes type VII is the latest in a group of severe skin infections to have now reached the United States,' Avrom Caplan, the report’s lead author and a dermatologist at New York University Grossman School of Medicine, wrote in a university news release.

Trichophyton mentagrophytes type VII is a drug-resistant fungus that causes skin disease in animals and humans and can be acquired through sexual contact, according to the Centers for Disease Control and Prevention.

In the report, Caplan wrote that the rash may look more like an eczema flare-up than a ringworm infection, which usually forms in a circular pattern on the skin.

The dermatologist said the infection is not fatal but can cause permanent scarring.

Caplan said he identified the first two cases of a different ringworm infection last year.

Those infections, caused by Trichophyton indotineae, are not sexually transmitted infections but are contagious and drug-resistant, the doctor reported.

Since then, Caplan’s NYU Langone Health team has identified 11 cases of Trichophyton indotineae ringworm in New York City, man yof them linked to travel in South Asia, according to a report published in JAMA Dermatology in May.

The report indicates the fungus is an emerging public health threat because it is resistant to standard therapies, including first-line antifungals, such as terbinafine.

Terbinafine, according to the Mayo Clinic, is a prescription tablet used to treat jock itch, athlete’s foot and other fungus infections of the body, scalp, fingernails and toenails

[shawandareneeobeymd]

The Lancet Psychiatry Looks at Black Mental Health in the US

In December of 2023, The Lancet Psychiatry journal published three literature reviews on the state of Black mental health in the United States, as well as an essay written by Black Americans on their lived experience in confronting systemic racism. Together, these papers comprehensively analyze the impact and effects of racism across a half century.

The authors were led by Ayana Jordan, MD, PhD, a physician scientist who serves as Barbara Wilson Associate Professor in the NYU Grossman School of Medicine’s Department of Psychiatry. Dr. Jordan is also community engagement pillar co-lead at the NYU Langone Health Institute for Excellence in Health Equity.

According to Dr. Jordan, the issue is multifaceted and challenging to solve. Centuries of racism and dehumanization, rooted in diaspora and slavery, have exposed many Black Americans to mental illness risk factors that include exposure to violence, police brutality, elevated homelessness, and living in poverty-stricken neighborhoods.

Compounding this, the current health care system tends to dismiss such backgrounds and thus invalidate the exposure to risk factors that many Black Americans face. Perceiving the system of care as both inequitable and not culturally informed, Black people are significantly less likely than their white counterparts to seek out mental health care.

The issue is no less acute in the medical community, with Black people historically excluded from taking leadership positions in health care research. Of those receiving US National Institutes of Health funding for independent research, fewer than 1 percent are Black Americans.

The authors also take a close look at the way in which myths of “whiteness and white supremacy” impact how mental health and mental illness have been framed. Differences in rates of substance use and mental illness are often utilized as evidence in propounding cultural and/or biological distinctions. What is lacking in this one-sided debate is a coherent explanation of the avoidable and unjust systemic economic and social policies that created such inequities.

An example of this inequity centers on the classification system, Diagnostic and Statistical Manual of Mental Disorders (DSM-5), used in conceptualizing mental illness in the academic community. DSM-5 situates mental illness as an issue defined by the behavior and physiology of the individual, and then works outward to incorporate race. This approach ignores the underlying impact of racism, and being racialized as Black, on mental health and reinforces prevalent systemic biases.

In working toward a set of solutions, the authors highlight the need for more community-based participatory research. This involves Black community members, as well as scientists, working together to improve Black Americans’ mental well-being. This inclusive approach is unique in encouraging the active participation of those with well-rounded cultural knowledge that can be of most use in supporting those with mental problems. When Black people have a voice, new and more nuanced models of care and intervention can be proposed, evaluated, and implemented.

On a practical level, the authors urge the launch of a large-scale study that will identify publicly available datasets spanning economic factors, political districting, and environmental exposure as they relate to racism. At the same time, such a study will integrate individual-level data in areas like emotional well-being and use this as a basis for further analysis. The achievable output will be a risk index that presents and quantifies exposures to racism, and provides a tool for understanding how this impacts emotional well-being and mental health.

[innonurse]

Novel technology identifies early indications of pandemic-linked stress and depression among healthcare personnel

- By InnoNurse Staff -

A recent research study reveals that an AI tool proficiently recognized signs of distress in hospital employees during their interactions with therapists in the early stages of the COVID-19 pandemic.

Read more at NYU Grossman School of Medicine and NYU Langone Health/PRNewswire

///

Other recent news and insights

The utilization of smartphone attachments may enhance equity in neurological assessment with regard to racial factors (UC San Diego)

[xtruss]

A New Study Says Gray Hair May Be Reversible! Bad News For Just For Men.

— By Tim Newcomb | May 2, 2023 | Popular Mechanics

Hans Neleman//Getty Images

Study links graying hair to stem cells getting stuck, unable to color new hair growth.

Stem cells travel back and forth within compartments, but when they get stuck in one compartment, they cannot regenerate into pigment cells.

Restoring mobility of the cells could allow the continuation of pigment production, eliminating graying hair.

If only our pesky stem cells didn’t get stuck in place after a while, maybe we wouldn’t have gray hair. Really. Thanks to a new study published in the journal Nature and led by researchers from New York University’s Grossman School of Medicine, the team revealed how stuck melanocyte stem cells (McSCs) can’t make the protein needed to pigment hair, potentially explaining gray hair.

Using mice as the research subjects, the team found that McSCs travel between compartments of developing hair follicles in a healthy situation. The differing compartments allow the McSCs to mature and pick up the protein that can regenerate into pigment cells and continually color hair as it grows. These McSCs shift back and forth between maturity levels over time as they continually move between the compartments, a unique aspect of the McSCs.

But in some cases, the McSCs can get stuck in the hair follicle bulge compartment and become unable to move back to the germ compartment, where the WNT proteins encourage the cells to regenerate into pigment cells. Getting stuck means no pigment cells, which means gray hair.

“It is the loss of chameleon-like function in melanocyte stems cells that may be responsible for graying and loss of hair color,” Mayumi Ito, study senior investigator and professor in the Ronald O. Perelman Department of Dermatology and Department of Cell Biology at NYU Langone Health, says in a news release. “These findings suggest that melanocyte stem cell motility and reversible differentiation are key to keeping hair healthy and colored.”

Basically, if the McSCs can keep moving—or, if they get stuck, we can somehow prod them to get going again—we should expect more colorful heads of hair the world over.

“Our study adds to our basic understanding of how melanocyte stem cells work to color hair,” Qi Sun, postdoctoral fellow at NYU Langone Health, says in a news release. “The newfound mechanisms raise the possibility that the same fixed positioning of melanocyte stem cells may exist in humans. If so, it presents a potential pathway for reversing or preventing the graying of human hair by helping jammed cells to move again between developing hair follicle compartments.”

The McSCs focus on pigment-making, and are different from cells responsible for hair growth, Sun says, so hair can to continue growing even without pigment. The NYU study showed that as the hair regrowth process aged, the number of McSC’s lodged in the follicle bulge continued to increase. At some points, this non-pigment producing follicle bulge contains roughly 50 percent of all McSCs.

The McSCs that remained mobile retained their ability to produce pigment, but with the ever-shifting requirements of McSCs breaking down over time, the rise of gray hair coincided with aging. And while stress has also been associated with graying hair, unrelated Harvard research says that stress simply increases the hair regrowth pattern, speeding up the aging process for hair follicles.

“For unknown reasons, the melanocyte stem cell system fails earlier than other adult stem cell populations, which leads to hair graying in most humans and mice,” according to the NYU study.

The next step for the NYU team involves looking at how we can get McSCs, once stuck, moving again. Because once they move, they create pigment. And that could mean the end of gray.

— Tim Newcomb is a journalist based in the Pacific Northwest. He covers stadiums, sneakers, gear, infrastructure, and more for a variety of publications, including Popular Mechanics. His favorite interviews have included sit-downs with Roger Federer in Switzerland, Kobe Bryant in Los Angeles, and Tinker Hatfield in Portland.

[fudaucellculture]

Study advances understanding of how melanocyte stem cells contribute to hair coloring

Certain stem cells have a unique ability to move between the growth compartments of hair follicles, but as people age they get stuck and thus lose their ability to mature and maintain hair color, a new study shows.

Led by researchers at NYU Grossman School of Medicine, the new work focused on cells in the skin of mice and also found cells in humans called melanocyte stem cells, or McSCs. Hair color is controlled by whether the non-functional but proliferating pool of McSCs within the follicle gets the signal to become mature cells that make the protein pigment responsible for the color.

The new study, published online April 19 in the journal Nature, shows that McSCs have remarkable plasticity. This means that during normal hair growth, as these cells move between the compartments of the developing follicle, they are constantly moving back and forth along the maturing shaft. It is within these compartments that McSCs are exposed to varying levels of protein signals that affect maturation.

Specifically, the team found that McSCs switch between their most primitive stem cell state and the next stage of maturation (the trans-amplification state), depending on their location.

The researchers found that as hair ages, falls out, and then repeatedly grows back, more and more McSCs get stuck in a stem cell compartment called the follicular bulge. They stay there, neither maturing to the transitional state nor returning to their original position in the germ chamber, where the WNT protein prompts them to regenerate into pigment cells.

The plasticity of McSCs is not present in other self-regenerating stem cells, such as those that make up the hair follicle itself, which are known to move in only one direction along a given time axis as they mature, the researchers said. For example, translocation-amplified hair follicle cells never reverted to their original stem cell state. This helps, in part, explain why hair continues to grow even when pigmentation fails, Sun said.

Earlier work by the same group at NYU showed that WNT signaling is required to stimulate McSCs to mature and produce pigment. The study also showed that McSCs were trillions of times less exposed to WNT signaling in the follicular bulge than in the hair germ compartment located just below the bulge.

In recent experiments in mice whose hair was physically aged by plucking and forced regrowth, the number of follicles containing McSCs in the follicular bulge increased from 15 percent before plucking to nearly half after forced aging. These cells still fail to regenerate or mature into pigment-producing melanocytes.

The researchers found that the stuck McSCs stopped their regenerative behavior because they were no longer exposed to high levels of WNT signaling, so they were unable to produce pigment in the new hair follicles that continued to grow.

In contrast, other McSCs that continued to move back and forth between the hair follicle bulge and hair germ retained the ability to regenerate into McSCs, mature into melanocytes, and produce pigment throughout the two-year study period.

"Loss of chameleon-like function in melanocyte stem cells may be responsible for hair graying and discoloration," said study senior investigator Mayumi Ito, Ph.D., professor in the Ronald O. Perelman Department of Dermatology and NYU Langone Ph.D. in Cell Biology, Faculty of Health.

"These findings suggest that melanocyte stem cell motility and reversible differentiation are key to maintaining healthy and colored hair," said Ito, who is also a professor in the Department of Cell Biology at NYU Langone.

The team plans to investigate ways to rejuvenate McSCs, or physically move them back to their germ chambers, where they can produce pigment, Ito said.

In the study, the researchers used recent 3D intravital imaging and scRNA-seq techniques to track cells aging and moving within each hair follicle in near real time.

[nuadox]

Missing data reconstructed via AI from Rapid MRI

- By Nuadox Crew -

A recent research by NYU Langone Health and Meta AI Research indicates that artificial intelligence can rebuild coarsely-sampled, rapid magnetic resonance imaging scans into high-quality pictures with the same diagnostic value as traditional MRI.

The fastMRI program is part of an effort to employ artificial intelligence to get MRIs to more patients faster and minimize appointment wait times. 

FastMRI scans were shown to be as accurate and of higher quality than standard scans in two studies. "Our new study translates the results from the earlier laboratory-based study and applies it to actual patients,"  explains Michael P. Recht, MD, the Louis Marx Professor of Radiology and chair of the Department of Radiology at NYU Grossman School of Medicine.

Previously, in a proof-of-concept study, the NYU Langone team mimicked faster scans by eliminating around three-fourths of the raw data generated by traditional, slow MRI scans. Using AI-accelerated imaging, an MRI examination that may take up to 30 minutes can be finished in less than 5 minutes.

FastMRI has made its data, models, and code accessible as an open-source project for other researchers and commercial MRI equipment makers. “This research represents an exciting step towards translating AI accelerated imaging to clinical practice,” stated Patricia M. Johnson, PhD, assistant professor of Radiology.

--

Header image: Image reconstruction in a 52-year-old man referred for clinical knee MRI with an anterior cruciate ligament tear. The ligament tear, indicated by the yellow arrows, can be seen equally well in (A) the conventional protocol images and (B) the deep learning protocol images. Credit: NYU Langone Health.

Source: NYU Langone Health

Full study: Johnson, Patricia M., et al. “Deep Learning Reconstruction Enables Prospectively Accelerated Clinical Knee MRI.” Radiology, Radiological Society of North America (RSNA), Jan. 2023. Crossref, https://doi.org/10.1148/radiol.220425.

Read Also

Proof of concept: 3D amplified MRI

[mariebenz]

NYU Oncologist Discusses Lung Cancer During Awareness Month

MedicalResearch.com Interview with:

Dr. Sally Lau Dr. Sally Lau MD Medical oncologist, NYU Langone’s Perlmutter Cancer Center Assistant professor of medicine NYU Grossman School of Medicine MedicalResearch.com: How big is the problem of lung cancer? Response: Amongst all cancer types, lung cancer is the number 1 killer in the US. MedicalResearch.com: Are there different types, and risk factors, for lung cancer?  Response:   Smoking is the most common risk factor for lung cancer. Smoking cessation programs have reduced lung cancer related deaths. The long-term effects of vaping are unknown. Increasingly, non-smokers are also getting lung cancers. The rising incidence is concerning. Some of the risk factors for non-smoker lung cancers are family history and air pollution. MedicalResearch.com: Are there symptoms of early lung cancer that patients should be aware of? Would you comment on recommendations for CT screening ie of high-risk patients? Response:  Early stage lung cancers are usually asymptomatic. In smokers, screening lung CTs help to diagnose cancers when they are still at an early stage and studies have shown that screening reduces lung cancer related deaths. There is no screening strategy for non-smokers, but studies are underway. MedicalResearch.com: How is treatment, and longevity, of lung cancer changing? Response:  Lung cancer is not just one disease. As we are learning more about its biology, we have new treatments that are much more effective with much less side effects. For many lung cancer patients with advanced disease the prognosis have dramatically improved, often measured in years with treatment. Our goal however, is to identify these patients earlier and treat with the new drugs to improve the cure rates. The information on MedicalResearch.com is provided for educational purposes only, and is in no way intended to diagnose, cure, or treat any medical or other condition. Always seek the advice of your physician or other qualified health and ask your doctor any questions you may have regarding a medical condition. In addition to all other limitations and disclaimers in this agreement, service provider and its third party providers disclaim any liability or loss in connection with the content provided on this website.     Read the full article

[sahraeyll]

NYU Langone Health New York $43,790-50,000 per year Permanent Full-time is one of the nation's top-ranked medical schools. For 175 years, NYU Grossman School of Medicine has trained thousands of physicians and scientists who have helped to shape the course of medical history and enrich the lives of countless people. An integral part of

[moremedtech]

AI Model Matches Radiologists’ Accuracy Identifying Breast Cancer in MRIs

AI Model Matches Radiologists’ Accuracy Identifying Breast Cancer in MRIs. Researchers from NYU Langone Health aim to improve breast cancer diagnostics with a new AI model. Recently published in Science Translational Medicine, the study outlines a deep learning framework that predicts breast cancer from MRIs as accurately as board-certified radiologists. The research could help create a foundational framework for implementing AI-based cancer diagnostic models in clinical settings. “Breast MRI exams are difficult and time-consuming to interpret, even for experienced radiologists. AI has tremendous potential in improving medical diagnosis, as it can learn from tens of thousands of exams. Using AI to assist radiologists can make the process more accurate, and provide a higher level of confidence in the results,”said study senior author Krzysztof J. Geras, an assistant professor in the Department of Radiology at the NYU Grossman School of Medicine. As a sensitive tool in breast cancer diagnostics, MRIs can help identify malignant lesions sometimes missed in mammograms and clinical applications. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is often used as a screening tool in high-risk patients and its applications are expanding. The tool can help doctors investigate potentially suspicious lesions or evaluate the extent of disease in newly diagnosed patients. This type of medical imaging can also help inform a doctor’s treatment plan, including whether to perform a biopsy or the extent of surgery needed. Both scenarios influence short- and long-term patient outcomes. According to the researchers, MRIs have untapped potential in predicting disease pathology and achieving a better understanding of tumor biology. Developing AI models from large, well-annotated datasets could be key in refining the sensitivity of these scans and reducing unnecessary biopsies. The researchers produced an AI model that improves the accuracy of breast cancer diagnosis using a dataset extracted from clinical exams performed at a NYU Langone Health breast imaging site. The dataset consisted of bilateral DCE-MRI studies from patients categorized as high-risk screening, preoperative planning, routine surveillance, or follow-up after a suspicious finding. They trained an ensemble of deep neural networks with 3D convolutions for detecting spatiotemporal features using 14,198 labeled MRI examinations with mixed precision on the NVIDIA Apex open-source library. According to the team, the use of this library made it possible to increase the batch size during training.

Overview of the study that trains and evaluates an AI system based on deep neural networks to predict the probability of breast cancer in DCE-MRI studies The networks were trained using the cuDNN-accelerated PyTorch framework on the university’s HPC cluster equipped with 136 NVIDIA V100 GPUs and NVIDIA NVLink for scaling memory and performance. Multi-GPU training was enhanced by the NVIDIA Collective Communication Library and training a single model took 12 days on average. “The GPUs did all the heavy lifting for training with high-dimensional data as we used full MRI volumes,”said Geras The model performance was validated on a total of 3,936 MRIs from NYU Langone Health. Using three additional datasets from Duke University, Jagiellonian University Hospital in Poland, and the Cancer Genome Atlas Breast Invasive Carcinoma data collection, the team validated that the model can work across different populations and data sources. The researchers compared the model results against five board-certified breast radiology attendings with 2 to 12 years of experience interpreting breast MRI exams. The clinicians interpreted 100 randomly selected MRI studies from the NYU Langone Health data. The team found no statistical significance in the results between the radiologists and the AI system. Averaging the AI and radiologist predictions together increased overall accuracy by at least 5%, suggesting a hybrid approach may be most beneficial. The model was also as accurate among patients with various subtypes of cancer, even among less common malignancies. Patient demographics, such as age and race, did not influence the AI system, despite the little training data available for some groups. The model output can also be combined with the personal preference of a clinician or patient deciding whether to pursue a biopsy after a suspicious finding. By default, all suspicious lesions classified with category BI-RADS 4 are recommended for biopsy, which leads to a substantial number of false positives. The AI model predictions can help avoid benign biopsies in up to 20% of all BI-RADS category 4 patients. The authors note that the work has a few limitations, including understanding how a hybrid approach could impact a radiologist’s decision in a hospital setting or how the model makes its predictions. “Although we only looked at retrospective data in our study, the results are strong enough that we are confident in the accuracy of the model. We look forward to further translating this work into clinical practice, deploying our AI systems in real life, and improving breast cancer diagnostics for both doctors and patients,”said study lead author Jan Witowski, a postdoctoral research fellow at NYU School of Medicine. Source: NVIDIA Read the full article

[reidbrod657]

Living With

The EPA suggests that to lower the wellness risks brought on by climate adjustment, ask your medical professional for suggestions on just how to stay clear of places or circumstances that can trigger a bronchial asthma strike or an allergic reaction. Also, prior to leaving your residence, check the Air Top quality Index, which demonstrates how polluted the air remains in your area. On days when the AQI is high, you ought to try to limit your outside tasks. People with persistent health conditions, lower-income, and areas of shade are overmuch impacted by both COVID-19 as well as climate adjustment, and pollution goes to the heart of both issues as a brand-new Harvard T.H. Chan School of Public healthstudyconfirms. We understand that African American areas are disproportionatelyexposed to air pollutionand we're currently seeing this air pollution drivinghigher death ratesfrom COVID-19.

Methods for local neighborhoods as well as states to reduce the danger of COVID-19 transmission throughout climate-related severe events like warm front, hurricanes, as well as wildfires. We have several reasons to take environment activity to boost our health and lowering dangers for infectious illness appearance is among them. Heat as well as moisture can impact your breathing, especially if you have asthma or COPD. Grabbing fried foods regularly can also result in weight gain. When you lug around excess extra pounds, your heart and also lungs have to function harder, making breathing harder, notes the Cleveland Center.

The major disease areas of worry are asthma, rhinosinusitis, persistent obstructive lung disease and also respiratory system system infections, yet the level to which these will certainly be impacted will differ according to the percentage of vulnerable people in an offered populace. Areas of higher poverty with minimal access to clinical services will suffer a lot more, as will certainly those areas with less-well-developed medical services, which will certainly include migrating populations as well as locations where population development is biggest. There is a need to far better specify the repercussions of repetitive exposure to cold air and the devices by which such direct exposure might change air passage function and also affect the results of individuals with pre-existing air passage illness. This might assist to advertise appropriate plan and also public health activities to deal with the incoming difficulties. The top respiratory tracts mucosal frameworks are specifically sensitive to cool air affects. Obstacles with cold dry air have actually been recommended to examine the state of nasal responsiveness in both sensitive and also non-allergic rhinitis.

This research discovered that even worse air top quality in China might increase transmission of infections that create influenza-like illnesses.

Since individuals with bronchial asthma already have inflamed airways, weather is more likely to have an effect, as breathing in hot, damp air induces air passage tightness in asthmatics.

Lots of people with COPD also have GERD, as well as having both can complicate your COPD symptoms, claims Jorge Mercado, MD, supervisor of lung medicine at NYU Langone Health Center-- Brooklyn.

This can damage lung cells, trigger coughing and hissing, and also bring about a lung infection.

We can as well as must do better if we wish to avoid the next transmittable pandemic.

Those on drug ought to carry it with them, as well as individuals who have been suggested bronchodilators should use them half an hour before leaving the house, to avoid the cold weather creating an abrupt tightening of the respiratory tracts when they are out. People living with COPD in Florida can take care of humidity levels making use of a dehumidifier, that makes a significant difference on extremely moist days. Some also suggest limiting outdoor tasks to the early morning or evening. Your tax-deductible contribution funds lung condition and lung cancer research study, brand-new treatments, lung wellness education, as well as more. Even though it may seem normal to have even more trouble taking a breath when climate condition are extreme, there are times when you should look for medical assistance.

We fit direct mixed-effects versions with a subject-specific arbitrary intercept to examine associations of 1-, 2- and also 7-day average of temperature level with lung function, using PROC MIXED in SAS Variation 9.4. We assessed the linearity of each organization by plotting generalised additive combined designs with punished splines making use of R. We examined if organizations in between temperature level and also lung feature were modified by season or family member humidity. Seasons were defined as wintertime (December-- February), spring (March-- Might), summer season (June-- August) and also autumn (September-- November). Based upon proof of differential susceptibility to temperature level and also seasonal irritants such as plant pollen amongst patients with bronchial asthma and also individuals with COPD, we examined if organizations with temperature varied by asthma and COPD condition.

Will Warmer Weather Slow The Spread Of Coronavirus?

Make certain the location you choose has tidy air-- this implies no cigarette smoke or severe fragrances. If your residence is not air conditioned, go to a cool public area, like an entertainment centre, public library, or shopping center. 1) Making sure that the breathing health results of environment modification are thought about in all conversations as well as suggested actions at EU level via the culture and also supporting the efforts of public interest organisations, such as the Health And Wellness and also Environment Partnership 57. The Atmosphere and also Health committee of the European Breathing Society held a workshop in Leuven in March 2008 in order to check out the particular health concerns of climate modification in connection with respiratory system disease. Although environment modification and also health have actually been attended to in the general clinical literature 3, 4, this declaration is the first from a specialist clinical culture as well as parallels the passion of the American Thoracic Culture in climate adjustment 5.

Naturally, the most effective areas to live for people with COPD are those with good air high quality. Today, several cities worldwide have elevated levels of air pollution-- some to the point of danger. To fight climate adjustment, we require to substantially reduce greenhouse gas exhausts. Limiting Greenhouse gas emissions to lower future influences is essential, but adjustment (climate-health preparedness) have to also simultaneously be supported. Most of these tasks likewise offer advantages for health (co-benefits) beyond those directly pertaining to environment change, such as raised physical activity and shifts to cleaner, less eco derogatory gas.

A Breath Of Fresh Air In Your Inbox

In close competition with Honolulu for the top area on this list, Maui's rank as No. 2 for fewest COVID deaths per capita was the differentiator. Our Individual Supporters can aid direct you or your loved one through the steps to take after a mesothelioma diagnosis. Our group has a combined experience of more than three decades in assisting cancer cells clients, and also includes a clinical physician, an oncology registered nurse and also a U. S. Navy expert. Anybody that notifications the winter causing a coughing, phlegm and also lack of breath, must take into consideration getting it took a look at by their GP. Sonata Elder Living neighborhoods offer independent living, aided living as well as memory treatment.

The gaseous contaminants O3 as well as nitrogen Net Zero Insulation - insulation removal dioxide were measured from state displays in Eastern Massachusetts, and exposures were estimated by averaging data from readily available sites. By convention, O3exposure was just taken a look at during the EPA tracking season for O3 in Massachusetts (April-- September). Our team of Client Advocates includes a medical doctor, a signed up nurse, health services administrators, experts, VA-accredited Insurance claims Representatives, an oncology patient navigator and hospice care professional.

In 2011, a research by the Epa that looked at the prices and benefits of the Clean Air act located that every $1 spent to decrease air pollution returns as much as $30 in benefits. The only thing our health and also our economic situation can not manage is environment inactiveness. It is important for individuals with COPD as well as their caregivers to recognize the indication of a COPD flare-up (times when COPD symptoms get a whole lot even worse.) Find out how to deal with and stop them. Indicators of intensifying COPD can include boosted shortness of breath, in addition to boosted coughing and also sputum.

Net Zero Insulation Inc

45 Edward St, London, ON, N6C 3H3, Canada

+1-519-914-6380

[newsyatra]

Apple Donated 1000 Watches For A Study Yy | एपल ने एक स्टडी के लिए 1000 एपल वॉच की डोनेट

Apple Donated 1000 Watches For A Study Yy | एपल ने एक स्टडी के लिए 1000 एपल वॉच की डोनेट

[ad_1]

<!-- Loading... -->

एपल की नई apple watch में कंपनी ने कई खास फीचर दिए हैं. Apple watch की खासियत है कि यह घड़ी पहनने वालों की धड़कनों का भी पता लगा सकती है. एपल का कहना है की यह घड़ी Parkinson’s disease का भी पता लगा सकती है.

हाल ही में यूनिवर्सिटी ऑफ नॉर्थ कैरोलिना स्कूल ऑफ मेडिसिन ने एक स्डटी करने…

[blueiscoool]

US Surgeons Transplant Pig Heart into Human Patient

U.S. doctors have transplanted a pig heart into a patient in a last-ditch effort to save his life — a first for medical science.

In a medical first, doctors transplanted a pig heart into a patient in a last-ditch effort to save his life and a Maryland hospital said Monday that he's doing well three days after the highly experimental surgery.

While it’s too soon to know if the operation really will work, it marks a step in the decades-long quest to one day use animal organs for life-saving transplants. Doctors at the University of Maryland Medical Center say the transplant showed that a heart from a genetically modified animal can function in the human body without immediate rejection.

The patient, David Bennett, a 57-year-old Maryland handyman, knew there was no guarantee the experiment would work but he was dying, ineligible for a human heart transplant and had no other option, his son said.

“It was either die or do this transplant. I want to live. I know it’s a shot in the dark, but it’s my last choice,” Bennett said a day before the surgery, according to a statement provided by the University of Maryland School of Medicine.

On Monday, Bennett was breathing on his own while still connected to a heart-lung machine to help his new heart. The next few weeks will be critical as Bennett recovers from the surgery and doctors carefully monitor how his heart is faring.

There’s a huge shortage of human organs donated for transplant, driving scientists to try to figure out how to use animal organs instead. Last year, there were just over 3,800 heart transplants in the U.S., a record number, according to the United Network for Organ Sharing, which oversees the nation’s transplant system.

"If this works, there will be an endless supply of these organs for patients who are suffering,” said Dr. Muhammad Mohiuddin, scientific director of the Maryland university's animal-to-human transplant program.

But prior attempts at such transplants — or xenotransplantation — have failed, largely because patients’ bodies rapidly rejected the animal organ. Notably, in 1984, Baby Fae, a dying infant, lived 21 days with a baboon heart.

The difference this time: The Maryland surgeons used a heart from a pig that had undergone gene-editing to remove a sugar in its cells that’s responsible for that hyper-fast organ rejection. Several biotech companies are developing pig organs for human transplant; the one used for Friday's operation came from Revivicor, a subsidiary of United Therapeutics.

“I think you can characterize it as a watershed event,” Dr. David Klassen, UNOS’ chief medical officer, said of the Maryland transplant.

Still, Klassen cautioned that it’s only a first tentative step into exploring whether this time around, xenotransplantation might finally work.

The Food and Drug Administration, which oversees such experiments, allowed the surgery under what’s called a “compassionate use” emergency authorization, available when a patient with a life-threatening condition has no other options.

It will be crucial to share the data gathered from this transplant before extending it to more patients, said Karen Maschke, a research scholar at the Hastings Center, who is helping develop ethics and policy recommendations for the first clinical trials under a grant from the National Institutes of Health.

“Rushing into animal-to-human transplants without this information would not be advisable,” Maschke said.

Over the years, scientists have turned from primates to pigs, tinkering with their genes.

Just last September, researchers in New York performed an experiment suggesting these kinds of pigs might offer promise for animal-to-human transplants. Doctors temporarily attached a pig’s kidney to a deceased human body and watched it begin to work.

The Maryland transplant takes their experiment to the next level, said Dr. Robert Montgomery, who led that work at NYU Langone Health.

“This is a truly remarkable breakthrough," he said in a statement. "As a heart transplant recipient, myself with a genetic heart disorder, I am thrilled by this news and the hope it gives to my family and other patients who will eventually be saved by this breakthrough.”

The surgery last Friday took seven hours at the Baltimore hospital. Dr. Bartley Griffith, who performed the surgery, said the patient’s condition — heart failure and an irregular heartbeat — made him ineligible for a human heart transplant or a heart pump.

Griffith had transplanted pig hearts into about 50 baboons over five years, before offering the option to Bennett.

“We’re learning a lot every day with this gentleman,” Griffith said. “And so far, we’re happy with our decision to move forward. And he is as well: Big smile on his face today.”

Pig heart valves also have been used successfully for decades in humans, and Bennett’s son said his father had received one about a decade ago.

As for the heart transplant, “He realizes the magnitude of what was done and he really realizes the importance of it,” David Bennett Jr. said. “He could not live, or he could last a day, or he could last a couple of days. I mean, we’re in the unknown at this point.”

By Carla K. Johnson and Lauran Neergaard.

First Pig-Heart Transplant Patient Dies 2 Months After Surgery

The first person to receive a heart transplant from a pig has died two months following the operation, the University of Maryland Medical Center announced.

57-year-old David Bennett died on Tuesday, though the hospital did not provide his cause of death. The statement released by UMMC said his condition started worsening several days ago.

"We are devastated by the loss of Mr. Bennett," said Bartley P. Griffith, MD, the doctor who performed the surgery. "He proved to be a brave and noble patient who fought all the way to the end. We extend our sincerest condolences to his family."

According to the statement, the transplant worked very well for "several weeks" and there was no sign of rejection.