#NHLBI

[pandemic-info]

A protein that disrupts cells’ energy centers may be a culprit in chronic fatigue syndrome | Science | AAAS

New study offers clues as to how exhaustion could arise in people with ME/CFS—and potentially related conditions such as Long Covid

People living with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) struggle not only with extreme exhaustion and the cognitive problems known as brain fog, but with a profound lack of information about what causes their symptoms and how to treat them. Scientists have yet to pin down the biology underlying the condition, which affects up to 2.5 million people in the United States alone, according to some estimates.

Now, researchers have identified a protein that’s present at unusually high levels in the muscles of people with ME/CFS and that disrupts cells’ ability to generate energy. The findings, reported today in the Proceedings of the National Academy of Sciences, could point to new therapeutics for this condition and for illnesses that share similar characteristics, such as Long Covid.

Akiko Iwasaki, an immunobiologist at Yale School of Medicine who was not involved in the work, praises the research as “very well done” but cautions that the suspect protein is likely “a piece of the puzzle, as opposed to explaining the whole disease.” The findings suggest it could act as one of several “middlemen” between whatever sparks the illness and symptoms such as fatigue, she says.

...

The NHLBI researchers wondered whether WASF3 was interacting with mitochondria, cellular compartments responsible for energy generation that have been suggested to malfunction in people with ME/CFS and Long Covid. Sure enough, by changing levels of WASF3 inside cultured cells from S1 as well as in other human and mouse cells, the team found  the protein could disrupt mitochondrial function. Specifically, high levels of WASF3 interfered with the assembly of mitochondrial proteins into molecular complexes that support normal energy production.

[drpedi07]

Body Mass Index (BMI) Calculator

Body mass index (BMI) is a measure of body fat based on height and weight that applies to adult men and women.

[greenfue]

انعدام الأمن الغذائي يتسبب في الإصابة بأمراض القلب والأوعية الدموية في مراحل لاحقة من العمر

يُكافح العديد من الشباب لتوفير لقمة العيش، ما قد يبدو مُشقةً مؤقتةً قد يكون له آثارٌ صحيةٌ دائمة. وجدت دراسةٌ جديدةٌ، أن من يعانون من انعدام الأمن الغذائي لديهم احتمالٌ أعلى بنسبة 41% للإصابة بأمراض القلب والأوعية الدموية في مراحل لاحقة من حياتهم. وحتى بعد الأخذ في الاعتبار الاختلافات الديموغرافية والاجتماعية والاقتصادية، ظل الخطر كبيرا. يؤثر انعدام الأمن الغذائي على أسرة من كل ثماني أسر في…

[covid-safer-hotties]

Also preserved in our archive

New research indicates that people who contracted COVID-19 early in the pandemic faced a significantly elevated risk of heart attack, stroke, and death for up to three years post-infection.

Those with severe cases saw nearly quadruple the risk, especially in individuals with A, B, or AB blood types, while blood type O was associated with lower risk. This finding highlights long-term cardiovascular threats for COVID-19 patients and suggests that severe cases may need to be considered as a new cardiovascular risk factor. However, further studies on more diverse populations and vaccinated individuals are needed to validate these results.

Long-Term Cardiovascular Risks Linked to COVID-19 Infection A recent study supported by the National Institutes of Health (NIH) found that COVID-19 infection significantly increased the risk of heart attack, stroke, and death for up to three years in unvaccinated people who contracted the virus early in the pandemic. This risk was observed in individuals with and without pre-existing heart conditions and confirms earlier research linking COVID-19 infection to a higher chance of cardiovascular events. However, this study is the first to indicate that the heightened risk may last as long as three years, especially for those infected during the first wave of the pandemic.

The study, published in the journal Arteriosclerosis, Thrombosis, and Vascular Biology, revealed that individuals who had COVID-19 early in the pandemic were twice as likely to experience cardiovascular events compared to those with no history of infection. For those with severe cases, the risk was nearly quadrupled.

“This study sheds new light on the potential long-term cardiovascular effects of COVID-19, a still-looming public health threat,” said David Goff, M.D., Ph.D., director for the Division of Cardiovascular Sciences at NIH’s National Heart, Lung, and Blood Institute (NHLBI), which largely funded the study. “These results, especially if confirmed by longer term follow-up, support efforts to identify effective heart disease prevention strategies for patients who’ve had severe COVID-19. But more studies are needed to demonstrate effectiveness.”

Genetic Factors and Blood Type’s Role in COVID-19 Complications The study is also the first to show that an increased risk of heart attack and stroke in patients with severe COVID-19 may have a genetic component involving blood type. Researchers found that hospitalization for COVID-19 more than doubled the risk of heart attack or stroke among patients with A, B, or AB blood types, but not in patients with O types, which seemed to be associated with a lower risk of severe COVID-19.

Scientists studied data from 10,000 people enrolled in the UK Biobank, a large biomedical database of European patients. Patients were ages 40 to 69 at the time of enrollment and included 8,000 who had tested positive for the COVID-19 virus and 2,000 who were hospitalized with severe COVID-19 between Feb. 1, 2020, and Dec. 31, 2020. None of the patients had been vaccinated, as vaccines were not available during that period.

The researchers compared the two COVID-19 subgroups to a group of nearly 218,000 people who did not have the condition. They then tracked the patients from the time of their COVID-19 diagnosis until the development of either heart attack, stroke, or death, up to nearly three years.

Higher Cardiovascular Risk in Patients With Severe Cases Accounting for patients who had pre-existing heart disease – about 11% in both groups – the researchers found that the risk of heart attack, stroke, and death was twice as high among all the COVID-19 patients and four times as high among those who had severe cases that required hospitalization, compared to those who had never been infected. The data further show that, within each of the three follow-up years, the risk of having a major cardiovascular event was still significantly elevated compared to the controls – in some cases, the researchers said, almost as high or even higher than having a known cardiovascular risk factor, such as Type 2 diabetes.

“Given that more than 1 billion people worldwide have already experienced COVID-19 infection, the implications for global heart health are significant,” said study leader Hooman Allayee, Ph.D., a professor of population and public health sciences at the University of Southern California Keck School of Medicine in Los Angeles. “The question now is whether or not severe COVID-19 should be considered another risk factor for cardiovascular disease, much like type 2 diabetes or peripheral artery disease, where treatment focused on cardiovascular disease prevention may be valuable.”

Allayee notes that the findings apply mainly to people who were infected early in the pandemic. It is unclear whether the risk of cardiovascular disease is persistent or may be persistent for people who have had severe COVID-19 more recently (from 2021 to the present).

Need for Broader Studies and Vaccine Impact on Risks Scientists state that the study was limited due to the inclusion of patients from only the UK Biobank, a group that is mostly white. Whether the results will differ in a population with more racial and ethnic diversity is unclear and awaits further study. As the study participants were unvaccinated, future studies will be needed to determine whether vaccines influence cardiovascular risk. Studies on the connection between blood type and COVID-19 infection are also needed as the mechanism for the gene-virus interaction remains unclear.

Study link: www.ahajournals.org/doi/10.1161/ATVBAHA.124.321001

[kennak]

妊娠前および妊娠初期中の肥満は、将来心血管疾患を発症するリスクの強力な指標であるようで、高血圧、子癇前症、妊娠糖尿病などの妊娠中の有害転帰と有意に関連していたという Circulation Research誌 。リンクは外部です） は、国立衛生研究所によって資金提供されました。 研究者らは、肥満が血圧に関連する心血管疾患や妊娠合併症の危険因子であることを知っています。 しかし、肥満と妊娠合併症のどちらが、妊娠後何年も経った人の心血管疾患のリスクに大きな影響を与えるかどうかはわかっていませんでした。 有害な妊娠転帰は妊娠中の心血管疾患リスクの増加と関連しているが、肥満患者の妊娠後数年間における心血管疾患リスクの増加のうち、合併症が占める割合はわずかであった。 「特定の妊娠合併症が明らかになり、すでに存在していた肥満などの心血管疾患のリスクが増大していることがわかっています。 この研究は、妊娠を考えている過体重または肥満の人に対する潜在的な介入のタイミングについての洞察を提供します」と、研究著者であり国立 ビクトリア・L・ペンバートン 心臓・肺・血液心臓血管科学部門の研究者である （RNC）は述べた。研究所 (NHLBI)、NIH の一部。 研究者らは、 nuMoM2b心臓健康調査 （リンクは外部） 4,200人以上の初産婦を対象とした から収集したデータを分析した。そのうち約半数は過体重または肥満だった。 彼らは、参加者の妊娠経験と2～7年後の健康状態を比較した。 研究者らは、妊娠初期に過体重または肥満だった母親は、正常体重の参加者に比べて、妊娠糖尿病を発症したり、高血圧を合併した妊娠をするリスクが約2倍であることを発見した。 これらの母親は、妊娠後に心血管疾患を発症するリスクも増加していました。

妊娠合併症は肥満者の短期的および長期的な心血管リスクを増加させ、そのリスクを明らかにします | 国立衛生研究所 (NIH)

[nursingwriter]

Asthma Public health consists of all the organized measures instituted to accomplish the following for the overall specific population: 1) to prevent disease; 2) to promote health; and 3) to contribute to prolonged lives. The unit of analysis for public health is an entire population, not any one individual in the population. The aim of public health is to establish and maintain conditions that promote health. Rather than focusing the eradication of certain diseases, public health takes a holistic, systematic approach. According to the World Health Organization (WHO), the three primary functions of a public health system are as follows: To identify public health priorities and problems through monitoring and assessment of community health and of at-risk populations; To solve recognized health problems at the local, state, and national level through the formulation and implementation of public policies; To ensure that all people have access to cost-effective, appropriate health care, including disease prevention and health promotion services. Although public health is organized around conventional borders established by local, state, and national governments, public health must attend to cross-border health risks and the impact of globalization on public health policies and practices. Indeed, public health policy addresses forces that originate outside state and national boundaries, such as global environmental change or the distribution and sales of dangerous products. Although asthma is not a contagious disease, it is a public health issue. Conditions that contribute to the development and recurrence of asthma symptomatology can often be manipulated and modified by human action on environments, a factor that fosters a public response to asthma. Asthma is a more common ailment than in the past, with the numbers approaching one in every 12 people exhibiting symptoms of asthma, which is a potentially fatal lifelong disease. Resources on evidence-based asthma care are available from the National Asthma Control Initiative (NACI) to patients, clinicians, and others who are able to use the asthma care and control guidelines to assist patients. The National Asthma Education and Prevention Program (NAEPP), an agency coordinated by the National Heart, Lung, and Blood Institute (NHLBI), established the NACI in 2008. The primary function of NACI is to ensure asthma guidelines implemented in the community, in health care settings, and in homes, schools, and places of employment. The agenda to reduce the public health burden of asthma crosses the conventional institutional and governmental boundaries. Local, state, and national public health care leaders, community stakeholders, and patients and their families are all working to improve the control over asthma. Yet, the incidence of asthma remains high. For instance, in 2010 alone, the cost to treat asthma in the U.S. was approximately $20.7 billion. The dynamics of the disease result in disproportionate rates of asthma and asthma-related disability, hospitalizations, visits to emergency departments, and lost productivity in people with low levels of income, populations of ethnic and racial minority, and children. In order to close the inequities gap and improve outcomes for people who have asthma, it is necessary to align and integrate the public health initiatives with those from clinical, educational, environmental, and occupational arenas. Outcomes can be improved for all people with asthma, if coalitions are institutionalized to gather available resources and engage diverse perspectives at the community and state levels. Increasing the capacity of communities to become more asthma-friendly and to economically tackle the disease requires a focused effort across levels of government. Basic steps for communities to take in order to address the threat and incidence of asthma are as follows: 1) Foster stakeholder collaboration through joint task forces and ad hoc coalitions; 2) conduct needs assessments to prioritize identified areas of improvement; 3) ensure better measurement and monitoring of the prevalence, mobidity, mortality, and risk factors of asthma; 4) make continuous improvement and accountability integral to collaborative effort; and 5) work to advance policy that will improve public health care structures, enhance care systems, and create environmental diligence and watch dog factions. As the national effort extends to the state and community levels, broader patterns of action are required to have an impact on asthma. A comprehensive manual has been published to help with this effort. The publication title is: Guidelines Implementation Panel (GIP) Report: Partners Putting Guidelines into Action. Through this guidelines effort, a number of stakeholder bodies have collaborated on the efforts to control asthma. Conclusion The collaborative efforts of organizations at various levels of the government and in public health have resulted in a number of positive changes in the quality of medical care received by people with asthma. These improvements include self-management support, case management and care coordination, monitoring of disparities, outreach and community education, housing quality, community capacity to control asthma, such as addressing ambient air quality and controlling other areas of environmental factors that affect asthma. References Trade, foreign policy, diplomacy and health. The World Health Organization . Retrieved http://www.who.int/trade/glossary/story076/en/ National Asthma Control Initiative (NACI). NIH National Heart, Lung, and Blood Institute, U.S. Department of Health and Human Services. Retrieved http://www.nhlbi.nih.gov/health/prof/lung/asthma/naci/ States, communities, and coalitions: Solving the asthma problem in our communities means bringing people and resources together. NIH National Heart, Lung, and Blood Institute, U.S. Department of Health and Human Services. Retrieved http://www.nhlbi.nih.gov/health/prof/lung/asthma/naci/audiences/communities.htm Read the full article

[thetempleofreading]

Pneumonia - Recovery | NHLBI, NIH

Take steps to help your body recover

The following steps can help your body recover from pneumonia.

Choose heart-healthy foods, because good nutrition helps your body recover.

Drink plenty of fluids to help you stay hydrated.

Don’t drink alcohol or use illegal drugs. Alcohol and illegal drugs weaken your immune system and can raise the risk of pneumonia complications.

Don’t smoke and avoid secondhand smoke. Breathing in smoke can worsen your pneumonia. Visit Smoking and Your Heart and Your Guide to a Healthy Heart. For free help quitting smoking, you may call the National Cancer Institute’s Smoking Quitline at 1-877-44U-QUIT (1-877-448-7848).

Get plenty of sleep. Good quality sleep can help your body rest and improve the response of your immune system. Visit How Sleep Works to get more information.

Get light physical activity. Moving around can help you regain your strength and improve your recovery. However, you may still feel short of breath. Activity that is too strenuous may make you dizzy. Talk to your provider about how much activity is right for you.

Sit upright to help you feel more comfortable and breathe more easily.

Take a couple of deep breaths several times a day.

[fitealthy]

The Health Benefits and Considerations of the DASH Diet

The DASH (Dietary Approaches to Stop Hypertension) diet is a well-researched eating plan designed to help lower blood pressure and promote overall health. Developed by the National Heart, Lung, and Blood Institute (NHLBI), the DASH diet focuses on consuming nutrient-rich foods while reducing sodium intake. While it has been widely praised for its health benefits, it is essential to understand its…

[molsons112000]

This is another reason why people don't survive from c p r. Because you're not doing the chest compressions, fast enough to supply the blood to the brain with enough continuous oxygen. So what happens is hypoxia sets in the brain cells start dying.... 🤔 it's better than nothing, but if you're going to do it, do it right!!!

And yes, warm breaths are better. Then the bag, because if it's cold air, it's harder for it to enter the lungs. That's why paramedics putting on oxygen mask.Don't work so well...

Cold temperatures cause our blood vessels to constrict. As a result, our blood circulation becomes poor which limits the availability of oxygen to many parts of the body. Your heart then has to work extra hard to pump blood.

https://portal.ct.gov › heatinghelp

Cold Weather and Our Health | Connecticut - CT.gov

While the air itself still contains the same percentage of oxygen when cold, it can be harder to get oxygen into your blood when the air is cold because cold air causes your airways to constrict, making it more difficult to inhale a sufficient amount of air, and can also lead to decreased blood circulation due to constricted blood vessels in response to the cold.

Key points to consider:

Physiological response:

When you breathe in cold air, your body tries to warm it up by constricting the airways in your lungs, which can limit the amount of oxygen reaching your bloodstream.

Blood circulation:

Cold temperatures also cause blood vessels to constrict, reducing blood flow to your lungs and potentially limiting the oxygen uptake.

Impact on certain individuals:

People with pre-existing lung conditions like asthma might experience more severe symptoms when breathing cold air due to airway sensitivity.

nhlbi, nih (.gov)

How the Lungs Work - The Respiratory System | NHLBI, NIH

Mar 24, 2022 — Airways * The airways are pipes that carry oxygen-rich air to the alveoli in your lungs. They also carry the waste gas carbon dioxide out of your l...

So it's important to have good circulation in the body and being active... but also keeping yourself properly clothed....

This is why people of color get plaque buildup in their arteries and in their brain in the winter... because their tissue is more sensitive, and so they tend to get lower levels of oxygen into the body, and this causes plaque build up and circulatory, as well as the brain..

Oh, as you see here, continuous hypoxia can promote arteriosclerosis and one of the other leaders of hypoxia is stress!!!

National Institutes of Health (NIH) (.gov)

https://www.ncbi.nlm.nih.gov › pmc

Continuous Hypobaric Hypoxia may Promote Atherosclerosis ...

by S Luo · 2023 · Cited by 4 — ... hypoxia may stimulate the degradation of collagen and consequently cause plaque instability. In the

Here you see hypoxia, being linked to plaque, buildup in the brain in alzheimer's!!!

National Institutes of Health (NIH) (.gov)

https://www.ncbi.nlm.nih.gov › pmc

What are the links between hypoxia and Alzheimer's disease? - PMC

by R Lall · 2019 · Cited by 64 — Association studies have recently showed that cerebral hypoxia, via both genetic and epigenetic

EMBO Press

https://www.embopress.org › doi

ER stress‐regulated translation increases tolerance to extreme ...

by M Bi · 2005 · Cited by 923 — An immediate reaction to hypoxia is a reduction in the rates of global protein synthesis that is thought to reduce

See your tailgating of me is causing continuous stress continuous stress causes hypoxia, continuous hypoxia. Causes plaque to build up in the arteries and lungs, you are killing me!!! You put me under financial stress. You put me on their stress from loneliness. You put me under stress when I go outside from tailgating.You put me under stress in unbelievable amounts of ways.You are killing me, killing me, killing me and killing me!!!!

Yes, stress can cause low levels of blood oxygen because when stressed, people tend to breathe shallowly, which doesn't effectively deliver enough oxygen to the blood, leading to a potential drop in blood oxygen saturation; this is often linked to the body's "fight or flight" response.

Key points about stress and oxygen levels:

Shallow breathing:

Under stress, people often breathe rapidly but shallowly, not fully filling their lungs and limiting oxygen intake.

Hyperventilation:

In some cases, high stress can lead to hyperventilation, which involves rapid, deep breaths that can also cause low blood oxygen levels due to the body expelling too much carbon dioxide.

Physiological response:

The stress response activates the sympathetic nervous system, which can affect breathing patterns and contribute to lower oxygen levels.

What can be done:

Mindful breathing:

Practicing deep, conscious breaths can help counteract the effects of stress on breathing and maintain adequate oxygen levels.

Relaxation techniques:

Yoga, meditation, and other relaxation practices can help manage stress and promote better breathing patterns.

Psych Central

Can Stress Cause Low Oxygen Levels? - Psych Central

Aug 12, 2022 — Stress can affect your body and mind and may leave you feeling short of breath. When there isn't enough oxygen being passed through your blood, your...

When you get stressed, you start to breathe faster yet less efficiently than normal. Those shallow breaths don't do a good job at sending oxygen to your blood. Instead those shallow breaths lower your oxygen levels, triggering you to breathe faster in order to get the level of oxygen your body needs.

https://precisionmedical.com › stre...

Stress and Oxygen Therapy - Precision Medical, Inc.

This is why people in the military, because they don't do things correctly with treating them and lowering stress in non combat situations that they cause buildups of plaque in the arteries and brain...

Yes, there is a link between stress and Alzheimer's disease:

Stress affects the immune system

The immune system plays an important role in dementia development, and stress can impact it.

Cortisol levels

When you're stressed, your body releases cortisol, a hormone that's been linked to memory problems. High levels of cortisol are associated with Alzheimer's disease.

Stress-related disorders

People with a history of stress-related disorders, such as PTSD or adjustment disorder, have an increased risk of dementia.

Accelerates disease progression

Stress can speed up the progression of Alzheimer's disease, including the formation of amyloid plaque and tau tangles.

Increases risk of cognitive impairment

Chronic stress increases the risk of mild cognitive impairment.

Additive effect with depression

The risk of Alzheimer's disease and mild cognitive impairment may be increased even more when chronic stress and depression are combined.

The majority of Alzheimer's cases have no known genetic cause, so environmental factors like stress are thought to play an important role.

Alzheimer's Society

Can stress cause dementia? | Alzheimer's Society

May 21, 2024

In summary, stress alone is a not a key factor in the onset of Alzheimer's disease; however, it may be important in the progression of the disease, as well as …

https://www.news-medical.net › St...

Stress and Alzheimer's Disease - News-Medical

Patients with stress-related disorders showed the highest and significantly increased risk for Alzheimer's dementia (HR = 1.22, 95% CI 1.04–1.56).Oct 1, 2023

https://www.nature.com › articles

Association between stress-related disorders and the ...

Veterans living with post-traumatic stress disorder (PTSD) or traumatic brain injury (TBI) have a higher risk of developing dementia or Alzheimer's. The Alzheimer's Association has information and resources to answer your questions about veterans and dementia risk, symptoms and treatment.

https://www.alz.org › resources › ve...

Veterans and Dementia - Alzheimer's Association

Yes, military personnel are more likely to develop Alzheimer's disease than the general population:

Traumatic brain injury (TBI)

TBIs can affect cognitive abilities like learning and thinking. Veterans of recent wars have experienced more serious head injuries than ever before.

Post-traumatic stress disorder (PTSD)

PTSD is a chronic anxiety disorder that can make it difficult to recover from traumatic events. People with PTSD are almost twice as likely to develop dementia.

Exposure to blasts

Shockwaves from military explosives can alter the connections between neurons in the hippocampus, which is involved in memory encoding.

Other factors

Veterans may also be at an increased risk due to their age, demographics, and socioeconomic factors.

The Alzheimer's research community is focusing on identifying individuals at high risk and preventing disease in its early stages.

NCBI

Military risk factors for Alzheimer's disease - PMC - NCBI

Mounting evidence suggests that traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD) resulting from military exposures increase the risk of de...

See, remember, this is stressed. Induced stress causes hypoxia and stress on a continuous basis causes plaque to build up in the arteries, causing culinary artery disease. Like in my father and he died of a mass of heart attack! My father was in the military and then under continuous stress!!!

Cardiovascular disease (CVD) is the leading cause of death in the United States among both men and women, accounting for 1 in every 4 deaths annually. The active duty component of the US Army (hereafter, “Army”) is afflicted more by CVD than by any other chronic disease.Jun 5, 2019

https://www.ahajournals.org › doi

Comparison of Cardiovascular Health Between US Army and ...

Yes, military personnel are more likely to have coronary artery disease (CAD) than civilians:

Combat deployments

Young service members and veterans who reported combat experiences had almost twice the odds of developing new-onset CAD than those without combat exposure.

Cardiovascular health

A study found that active-duty Army personnel had worse cardiovascular health than civilians of similar ages.

Veteran status

Veterans have a higher risk of having CAD than non-veterans. Male veterans are at an even higher risk than female veterans.

Other risk factors for CAD include:

Diabetes

Hyperlipidemia

Smoking

Hypertension

Family history of CAD

Chronic noise exposure

NCBI

Assessment of risk factors for coronary artery disease in ...

Results: Data analysis indicated that the risk factors including diabetes, hyperlipidemia, smoking, hypertension, and positive family history of CAD enhance the...

So I watched this piece of s***Federal government piece of garbage state piece of garbage county and local governments allow people to drive inappropriately, allow people to act inappropriately in all environments, causing massive stress, destroying us internally and externally!!!

So I noticed this with my first breakdown, the chronic stress caused me to get toe fungus, and then it caused me to get warts, and these are all signs of immense stress, and then they cause you to get different skin issues, and then that chronic stress causes chronic hypaxia, chronic. Hypaxia causes parkinson's!!!

Yes, chronic stress can cause a variety of skin problems, including:

Acne: Stress can make acne worse by causing the body to produce more oil.

Psoriasis and eczema: Stress can trigger flare-ups of these skin conditions.

Rosacea: Stress can trigger this inflammatory condition, which causes redness and visible blood vessels on the face.

Hives: Stress can trigger chronic urticaria, also known as hives.

Vitiligo: Stress can weaken the immune system, making the body more vulnerable to autoimmune diseases like vitiligo, which causes loss of skin color.

Hair loss: Stress can contribute to hair thinning and loss.

Wrinkles: Stress hormones break down collagen and elastin in the skin, which can speed up the aging process and cause more wrinkles.

Stress can also impair the skin's ability to heal wounds.

To treat stress-related skin issues, you can:

Manage stress

Try to reduce stress through lifestyle changes like getting enough sleep, exercising regularly, eating well, meditating, and spending time with friends and loved ones. You can also consider talking to a therapist or other mental health professional.

Practice good skincare

Wash your face with a gentle cleanser, use sunscreen regularly, and keep your skin moisturized.

Stress rashes usually go away on their own, but you should contact a doctor if you suspect your hives are an allergic reaction.

Bupa UK

Does stress cause skin problems? - Bupa UK

Ongoing stress can also weaken your immune system. This makes you more vulnerable to infection and skin diseases like vitiligo (loss of skin colour) and chronic...

Yes, hypoxia, or low oxygen supply, may be a factor in the development of Parkinson's disease (PD):

Case studies

Some case studies have shown that exposure to hypoxia can trigger Parkinsonian symptoms, such as tremors, limb rigidity, and gait disturbances.

Research

Research suggests that hypoxia may be linked to the pathology of PD by increasing the expression and aggregation of alpha-synuclein (α-syn), a protein that is pathogenic in PD.

Hypoxia conditioning

Some research suggests that mild hypoxia can have neuroprotective effects, and that this could be a potential therapeutic strategy for PD.

PD is a neurodegenerative disorder that causes the death of dopamine-producing neurons, which leads to movement problems. The exact cause of this neuronal loss is unknown, but it may be linked to environmental factors, genetics, and molecular pathways.

NCBI

Hypoxia Signaling in Parkinson's Disease: There Is Use in Asking ...

Jul 29, 2021 — Parkinson's disease is a neurodegenerative disorder characterized by the death of a specific subset of dopamine-producing neurons. This triggers pro...

Although stress does not directly cause vertigo, it can trigger symptoms. Vertigo results from a dysfunction in the vestibular system. The vestibular system helps people maintain their balance and starts in their ears. Tiny hairs in the inner ear detect head movements and send messages to the brain.Jan 15, 2024

https://www.medicalnewstoday.com › ...

Vertigo and stress: Is there a link? - MedicalNewsToday

Stress doesn't directly cause vertigo, but it can trigger or worsen symptoms. Stress can affect the vestibular system, which controls balance, in several ways, including:

Hormones

Stress hormones like cortisol can impact the nervous system.

Muscle tension

Anxiety can cause muscles to tense up, making it harder for blood to reach the brain and inner ear.

Brain activity

The brain areas responsible for balance and stress are connected, so activity in one area can impact the other.

Immune system

Stress can weaken the immune system, which can lead to viral overload and viral vertigo.

Some people with anxiety disorders experience vertigo more often. For example, someone with social anxiety might feel dizzy when in a crowded room.

To prevent vertigo caused by stress, you can try: Managing stress with coping skills like deep breathing and mindfulness, Maintaining a regular sleep schedule, Eating a balanced diet, and Exercising more.

If you're experiencing vertigo and stress, you can talk to a healthcare professional to learn about treatments.

Healthline

Can Stress Cause Vertigo? Risk Factors, Treatment, and Prevention

Oct 8, 2020

Hey These are signs that psychologists need to understand that stress anxiety causes wartz... See, they have to be good therapist. It also causes extreme weight, gain or extreme Weight loss These are all signs of psychological stress!!!!

Yes, stress can cause warts by weakening the immune system's ability to fight off viruses like HPV, which causes warts:

How stress causes warts

Stress causes the release of hormones that build up over time, weakening the immune system.

Other risk factors

Other factors that can increase the risk of getting warts include having a weak immune system, being sexually active, or having hormonal disorders.

How HPV is spread

HPV is spread through skin-to-skin contact, shaking hands, turning doorknobs, typing on keyboards used by many, or sharing common shoes or towels.

How warts appear

HPV causes too much keratin to develop in the top layer of skin, which produces the rough, hard texture of a wart.

How warts can affect self-esteem

Warts can affect a patient's self-esteem and confidence, and sometimes make them feel stigmatized in certain social situations.

How to get rid of warts

Over-the-counter options like salicylic acid gel, liquid, or pads can help get rid of warts. You can also try covering the area with duct tape after applying salicylic acid, then soaking the area in water after removing the duct tape.

Some studies show that people with warts have lower B12 levels, and that zinc can help improve and clear warts.

The Economic Times

warts: What causes warts, how are they transmitted, and how to get rid of them? - The Economic Times

Apr 24, 2023

So I told you, I got warts, and I got tofungus continuous, because of continuous stress from my first now second breakdown...

Yes, stress can contribute to toe fungus in a number of ways:

Sweating

Stress can impact your sweat patterns, leading to excess moisture on your feet. This can cause skin texture issues, which can lead to corns and friction between your toes.

Weakened immune system

Stress can weaken your immune system, making you more susceptible to fungal infections.

Self-inflicted habits

People who are stressed or nervous may develop habits or tics that can lead to skin, hair, or nail problems.

Other factors that can increase your risk of toenail fungus include:

Being older

Having a family history of fungal infections

Having a weakened immune system

Having circulation issues

Wearing tight-fitting shoes

Walking barefoot in damp public places

Having a previous injury or infection to the skin or nail

Fungal infections are caused by microscopic organisms called fungi, which can enter your skin or nail through cracks or splits. You can pick up the fungi from skin-to-skin contact with someone who has a fungal infection, or by breathing in fungus from the environment.

Errol Gindi, DPM

What Causes Toenail Fungus? - Errol Gindi, DPM

What is toenail fungus? Fungal infections occur when yeasts or molds that exist in the environment around you enter your nail or the skin of your toes, typicall...

So the government flooded the country in with refugees, legal and illegal immigration that cause unbelievable amounts of stress related to that the sixties got more violent, the seventies were the most violent decade ever and violent crimes have been through the roof ever since!!! 😳 you can't flood people into the country. They must undergo significant educational process before they can be released into the country. Training them to understand what is culturally appropriate in the united states, so they fit in correctly!!!!!!

And you wonder why God said what he did that people that did this to me the first time he predicted it coming on, and then he predicted it the second time he would do it to me. N the second time he said, if they do it to you again, then i'm going to condemn them all!!!! And you did it to me again? And you constantly put me in the situations of incredible stress unbelievably destroying me!!!

But again, this is for therapists to understand and i'm communicating this the crete awareness, because facebook constantly says I go against the community, facebook goes against a community.I believe it's being run by demons now!!!!

Yes, chronic stress can indeed lead to both extreme weight gain and weight loss, primarily due to its impact on hormone levels, particularly cortisol, which can significantly alter appetite and metabolism, causing individuals to either overeat or lose interest in food depending on the situation.

How stress can cause weight gain:

Increased cortisol levels:

When stressed, the body releases cortisol, which can stimulate appetite and cravings for high-calorie foods, leading to overeating and fat storage, especially around the abdomen.

Disrupted eating patterns:

Stress can lead to irregular meal times, skipping meals, and emotional eating, contributing to unhealthy dietary choices.

Slowed metabolism:

Chronic stress can affect metabolic rate, making it harder to burn calories.

How stress can cause weight loss:

Decreased appetite:

In some cases, high stress can suppress appetite, leading to reduced calorie intake and potential weight loss.

Digestive issues:

Stress can disrupt digestion, leading to malabsorption of nutrients and weight loss.

Sleep disturbances:

Stress often disrupts sleep patterns, which can further impact hormone regulation and metabolism, contributing to weight loss.

Important points to remember:

Individual variations:

The relationship between stress and weight can vary significantly between individuals, depending on their stress response, eating habits, and lifestyle.

Managing stress is key:

To prevent stress-related weight changes, managing stress through techniques like exercise, relaxation practices, and mindfulness is crucial.

WebMD

Surprising Reasons You're Gaining Weight

Jun 1, 2024 — When life's demands get too intense, our bodies go into survival mode. Cortisol, the "stress hormone," is secreted, which causes an increase in appet...

But I also point this out so everybody can understand how these issues affect you. So doctors can mitigate these situations, so these extreme negative conditions don't happen to people, whether you're white or of color meaning darker color than white!!!!!

[rodspurethoughts]

Guard Against COPD at Every Stage of Life

(Family Features) Take a deep breath. Now ask yourself: When was the last time you thought about breathing? For people with chronic obstructive pulmonary disease (COPD), breathing is often front of mind because it can be difficult, and it gets worse over time. Dealing with COPD There is no cure yet for COPD, but experts from the National Heart, Lung, and Blood Institute (NHLBI) recommend these…

[covid-safer-hotties]

Also preserved on our archive

NIH-funded study focused on original virus strain, unvaccinated participants during pandemic.

Infection from COVID-19 appeared to significantly increase the risk of heart attack, stroke, and death for up to three years among unvaccinated people early in the pandemic when the original SARS-CoV-2 virus strain emerged, according to a National Institutes of Health (NIH)-supported study. The findings, among people with or without heart disease, confirm previous research showing an associated higher risk of cardiovascular events after a COVID-19 infection but are the first to suggest the heightened risk might last up to three years following initial infection, at least among people infected in the first wave of the pandemic.

Compared to people with no COVID-19 history, the study found those who developed COVID-19 early in the pandemic had double the risk for cardiovascular events, while those with severe cases had nearly four times the risk. The findings were published in the journal Arteriosclerosis, Thrombosis, and Vascular Biology.

“This study sheds new light on the potential long-term cardiovascular effects of COVID-19, a still-looming public health threat,” said David Goff, M.D., Ph.D., director for the Division of Cardiovascular Sciences at NIH’s National Heart, Lung, and Blood Institute (NHLBI), which largely funded the study. “These results, especially if confirmed by longer term follow-up, support efforts to identify effective heart disease prevention strategies for patients who’ve had severe COVID-19. But more studies are needed to demonstrate effectiveness.”

The study is also the first to show that increased risk of heart attack and stroke in patients with severe COVID-19 may have a genetic component involving blood type. Researchers found that hospitalization for COVID-19 more than doubled the risk of heart attack or stroke among patients with A, B, or AB blood types, but not in patients with O types, which seemed to be associated with a lower risk of severe COVID-19.

Scientists studied data from 10,000 people enrolled in the UK Biobank, a large biomedical database of European patients. Patients were ages 40 to 69 at the time of enrollment and included 8,000 who had tested positive for the COVID-19 virus and 2,000 who were hospitalized with severe COVID-19 between Feb. 1, 2020, and Dec. 31, 2020. None of the patients had been vaccinated, as vaccines were not available during that period.

The researchers compared the two COVID-19 subgroups to a group of nearly 218,000 people who did not have the condition. They then tracked the patients from the time of their COVID-19 diagnosis until the development of either heart attack, stroke, or death, up to nearly three years.

Accounting for patients who had pre-existing heart disease – about 11% in both groups – the researchers found that the risk of heart attack, stroke, and death was twice as high among all the COVID-19 patients and four times as high among those who had severe cases that required hospitalization, compared to those who had never been infected. The data further show that, within each of the three follow-up years, the risk of having a major cardiovascular event was still significantly elevated compared to the controls – in some cases, the researchers said, almost as high or even higher than having a known cardiovascular risk factor, such as Type 2 diabetes.

“Given that more than 1 billion people worldwide have already experienced COVID-19 infection, the implications for global heart health are significant,” said study leader Hooman Allayee, Ph.D., a professor of population and public health sciences at the University of Southern California Keck School of Medicine in Los Angeles. “The question now is whether or not severe COVID-19 should be considered another risk factor for cardiovascular disease, much like type 2 diabetes or peripheral artery disease, where treatment focused on cardiovascular disease prevention may be valuable.”

Allayee notes that the findings apply mainly to people who were infected early in the pandemic. It is unclear whether the risk of cardiovascular disease is persistent or may be persistent for people who have had severe COVID-19 more recently (from 2021 to the present).

Scientists state that the study was limited due to inclusion of patients from only the UK Biobank, a group that is mostly white. Whether the results will differ in a population with more racial and ethnic diversity is unclear and awaits further study. As the study participants were unvaccinated, future studies will be needed to determine whether vaccines influence cardiovascular risk. Studies on the connection between blood type and COVID-19 infection are also needed as the mechanism for the gene-virus interaction remains unclear.

This study was supported by NIH grants R01HL148110, R01HL168493, U54HL170326, R01DK132735, P01HL147823, R01HL147883, and P30ES007048.

About the National Heart, Lung, and Blood Institute (NHLBI): NHLBI is the global leader in conducting and supporting research in heart, lung, and blood diseases and sleep disorders that advances scientific knowledge, improves public health, and saves lives. For more information, visit www.nhlbi.nih.gov.

About the National Institutes of Health (NIH): NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit www.nih.gov.

NIH…Turning Discovery Into Health®

Study Allayee, H, et al. COVID-19 Is a Coronary Artery Disease Risk Equivalent and Exhibits a Genetic Interaction With ABO Blood Type(link is external). [2024] Arteriosclerosis, Thrombosis, and Vascular Biology. DOI: 10.1161/ATVBAHA.124.321001

[nursingwriter]

Improving Health for Children With Asthma Childhood Asthma Improving Health Outcomes for Inner-City Children with Asthma Improving Health Outcomes for Inner-City Children with Asthma Centers for Disease Control and Prevention (CDC) engages in active surveillance of childhood asthma because it is prevalent, contributes significantly to childhood morbidity, and imposes an economic burden on families (CDC, 2012). The main recommendations for diagnosing and managing asthma by the National Heart, Lung, and Blood Institute (NHLBI) and the National Asthma Education and Prevention Program (NAEPP) at the National Institutes of Health are: (1) objective measures of lung function, (2) reduce or eliminate environmental triggers, (3) patient and family education, and (4) long-term disease management using comprehensive pharmacotherapy (2007, p. 1). Not only are these recommendations important for limiting the disease burden during childhood, but recent studies have begun to uncover links between chronic childhood respiratory problems and the development of chronic obstructive pulmonary disease (COPD) in older adults (Guerra, Stern, & Morgan, 2013). Among the children who suffer from asthma, minority children tend to have the worst outcomes (Moorman, Person, Zahran, & CDC, 2013). This is due in part to children and adolescents having poor knowledge about the use and benefits associated with inhaled corticosteroid therapy (Mosnaim et al., 2014). Patient and family education about asthma and treatment regimens therefore represents one important method for reducing not only disease burden, but also health disparities suffered by U.S. children. This research proposal will therefore investigate the efficacy of family education for reducing asthma-associated morbidity and economic burden. Literature Review Among all U.S. children, 9.4% have reported current asthma (Howden & Meyer, 2011). Based on the 2010 U.S. Census data this represented almost 7 million children. Asthma attacks among children were also very common, with approximately 56.1% of these children, between the ages of birth and 17-years, reporting an asthma attack during the same period (Moorman, Person, Zahran, & CDC, 2013). In 2007, 185 asthma attacks resulted in the death of the child (AAAAI, 2014). An average of $1,039 was spent annually per child diagnosed with asthma (CDC, 2012), which translates into about $7.2 billion overall. In addition, these children missed 10.5 million days of school in 2008 as a result of their disease (CDC, 2012). When asthma prevalence is examined along racial lines, minorities tend to suffer more (Moorman, Person, Zahran, & CDC, 2013). Close to 17% of non-Hispanic African-American children suffered from asthma in 2009 and between 2001 and 2009 the prevalence of asthma within this demographic nearly doubled (AAAAI, 2014). Poverty and access to health care services therefore play a significant role in determining asthma prevalence. Efforts to improve health outcomes for minority children with asthma have varied greatly. A recent randomized, controlled trial (RCT) tested the efficacy of peer support and peer messages sent to MP3 players for increasing inhaled corticosteroid therapy (ICT) compliance among minority adolescents, but found no benefit (Mosnaim et al., 2013). When the same research group examined a number of possible predictive factors, including demographic variables, disease history, exacerbations, depression, asthma knowledge, ICT knowledge, and ICT self-efficacy, only older age and less ICT knowledge were significant predictors of low ICT adherence (Mosnaim et al., 2014). These results are consistent with the NHLBI/NAEPP (2007) guidelines recommending patient education as an important disease management strategy with the potential to reduce health disparities. As Julian and colleagues (2014) noted in their recent research paper, very few studies have examined the efficacy of patient and family education on health outcomes. Accordingly, they studied the impact of a therapeutic education intervention on outcome variables, including child quality of life, caregiver quality of life, treatment compliance, lung function testing, asthma attack incidence, emergency department visits, hospital admissions, missed school days, and parent sick days due to a sick child. The intervention took place in the pediatric pulmonary department at the Clermont-Ferrand teaching hospital in France and consisted of three phases: (1) disease description and written action plan for asthma attacks during the first consultation, (2) individual educational diagnosis by a doctor with patient and caregiver, and (3) group consultation with up to four families and two doctors for the purpose of providing detailed descriptions of asthma pathophysiology, symptomology, triggers, attacks, and treatments. The first two phases occurred on the same day and the third phase a month later. Outcome measures were collected using a pretest and posttest study design without a control, with the posttest taking place four months after the initial consultation. The quality of life for the children enrolled in the study, which were between the ages of 5- and 11-years, did not improve significantly, but it did for the parents (p Read the full article

[leedsomics]

Genetic Architecture and Analysis Practices of Circulating Metabolites in the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program

Circulating metabolite levels partly reflect the state of human health and diseases, and can be impacted by genetic determinants. Hundreds of loci associated with circulating metabolites have been identified; however, most findings focus on predominantly European ancestry or single study analyses. Leveraging the rich metabolomics resources generated by the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program, we harmonized and accessibly cataloged 1,729 circulating metabolites among 25,058 ancestrally-diverse samples. We provided recommendations for outlier and imputation handling to process metabolite data, as well as a general analytical framework. We further performed a pooled analysis following our practical recommendations and discovered 1,778 independent loci associated with 667 metabolites. Among 108 novel locus-metabolite pairs, we detected not only novel loci within previously implicated metabolite associated genes, but also novel genes (such as GAB3 and VSIG4 located in the X chromosome) that have putative roles in metabolic regulation. In the sex-stratified analysis, we revealed 85 independent locus-metabolite pairs with evidence of sexual dimorphism, including well-known metabolic genes such as FADS2, D2HGDH, SUGP1, UTG2B17, strongly supporting the importance of exploring sex difference in the human metabolome. Taken together, our study depicted the genetic contribution to circulating metabolite levels, providing additional insight into the understanding of human health. http://dlvr.it/TB2sNn

[thetempleofreading]

Pneumonia - Recovery | NHLBI, NIH

It may take time to recover from pneumonia. Some people feel better and are able to return to their normal routines in 1 to 2 weeks. For others, it can take a month or longer. Most people continue to feel tired for about a month. Talk with your healthcare provider about when you can return to your

[dr-smita-goel-homeopathy-clinic]

*Dr. Smita Goel Homeopathy Clinic*

www.thehomeopathyclinic.co.in

A person with Raynaud's disease experiences pain in the extremities, for example, the fingers, when temperatures drop.

Blood vessels narrow and almost completely shut down. Fingers or toes turn from white to blue and, then, as the blood returns, they flush red.

Also known as Raynaud's syndrome or Raynaud's phenomenon, As per research females are an estimated nine times more likely to be affected than males.

Fast facts on Raynaud's disease are followings:

• Raynaud's disease is caused by peripheral blood vessels overreacting to cold.

• Maurice Raynaud first described the disease in 1862.

• Females and people living in colder climates are more often affected.

• A capillaroscopy can help diagnose Raynaud's disease.

Living with Raynaud's

People who are prone to Raynaud's can take measures to avoid some triggers.

The National Heart, Lung, and Blood Institute (NHLBI) suggest:

• wrapping up and keeping the house warm when temperatures are cold

• as far as possible, avoiding emotional stress

• exercise to promote a healthy lifestyle and reduce stress

• avoiding medicines and substances that trigger the symptoms

• limiting consumption of caffeine and alcohol

• not smoking

Homeopathy has good treatment for it. Getting medical help may prevent a worsening of symptoms and serious complications.

Causes

Exactly what causes Raynaud's remains unclear, but a hyperactivation of the sympathetic nervous system is known to cause an extreme narrowing of the blood vessels, known as vasoconstriction.

It can happen when the person enters a cold place, opens a freezer, or puts their hands in cold water.

Some people experience symptoms when faced with stress, even without an associated drop in temperature.

In healthy individuals, the circulatory system in the extremities, such as the fingers and toes, reacts to conserve heat in cold conditions. The small arteries that supply the skin with oxygen narrow to minimize the amount of heat lost through the exposed skin surface.

In people with Raynaud's disease, this narrowing is excessive. This is what causes the blood vessels almost to shut down.

Types

There are two types of Raynaud's disease: Primary and secondary.

Primary Raynaud's, or Raynaud's disease, is more common, and it affects people who do not have a secondary medical condition.

Secondary Raynaud's, or Raynaud's phenomenon or syndrome, results from an underlying medical issue. It is less common and tends to be more serious.

Causes of secondary Raynaud's

Causes of secondary Raynaud's include:

Diseases of the arteries: Atherosclerosis, a build-up of plaque in blood vessels, or Buerger's syndrome, a disorder where blood vessels in the hands and feet become inflamed, can cause Raynaud's symptoms. Primary pulmonary hypertension has also been linked to the disease.

Diseases of the connective tissue: Most people with scleroderma, a disease leading to hardened skin, have Raynaud's disease. The symptoms are commonly linked to lupus, rheumatoid arthritis, and Sjogren's syndrome, an autoimmune disease affecting glands.

Repetition or vibration: People whose hobbies or jobs require repetitive movements, such as typing or playing the guitar or piano, are at risk of developing Raynaud's symptoms. Those whose jobs involve using vibrating tools, such as a jackhammer, are also at risk.

Carpal tunnel syndrome: This condition puts pressure on the nerves traveling to the hand, and it increases susceptibility to Raynaud's symptoms.

Medications: Drugs that can induce Raynaud's include beta blockers, migraine medications containing ergotamine or sumatriptan, ADHD medications, some chemotherapy drugs, and some over-the-counter cold remedies.

Exposure to certain substances: Smoking narrows blood vessels and is a possible cause of Raynaud's. Other chemicals, such as vinyl chloride, may also play a role.

Injuries: Raynaud's can start after injuries such as frostbite, a broken wrist, or local surgery.

Raynaud's tends to affect females more than males. Primary Raynaud's normally starts between the ages of 15 years and 25 years, and secondary Raynaud's between 35 and 40 years.

The condition appears to run in families. A person a first-degree relative with Raynaud's is more likely to develop it.

Possible pathways of Raynaud's disease

The exact pathways of Raynaud's disease are not known, but it probably results from a combination of factors, and the combination of factors probably differs between individuals.

Other possibilities

Platelet activation appears to be higher in people with Raynaud's. Platelets are components in blood that clump together to help prevent bleeding.

Fibrinolysis is a natural reaction that takes place in the body to reduce clotting. Some studies have linked low levels of fibrinolysis with Raynaud's.

Oxidative stress is caused by an increase in free radicals, and it could be involved in Raynaud's.

Symptoms

Raynaud's disease causes blood vessels in the hands or feet to overreact to the cold, causing numbness and pain.

Raynaud's disease affects some people when they are exposed to the cold.

When temperatures drop, the blood vessels contract in the fingers or toes. This contraction causes hypoxia, or lack of oxygen, to the affected tissues. Fingers and toes will feel cold to the touch and possibly numb.

Often, the affected area will turn white, then later turn blue. Once the area is warmed and blood flow returns, a tingling sensation may accompany a red flush and, possibly, swelling. There may also be a painful, throbbing sensation.

Toes and fingers are most commonly affected, but Raynaud's can affect the nose, lips, and ears.

Some women may experience Raynaud's phenomenon of the nipples, especially during breastfeeding. It causes severe throbbing, similar to that experienced with a fungal Candida albicans infection, which can lead to misdiagnosis.

An episode normally lasts around 15 minutes, including the time it takes for the body to normalize.

Raynaud's feet

Raynaud's syndrome can affect either the hands or feet, or both.

To reduce the risk of an attack, it can help to keep the feet and hands warm, avoid smoking, and get enough exercise.

If an attack starts, it may be reduced or prevented by warming the hands and feet at once, for example, by massaging them.

The feet and hands should be protected from cuts, bruises, and other injuries as far as possible, because the lack of circulation can make it harder for them to heal. Use lotion to prevent the skin from cracking, and make sure you have comfortable, well-fitting shoes.

Complications

Raynaud's is not normally life-threatening, but complications can occur.

Chilblains happen when there is a problem with the blood circulation, and Raynaud's is one possible cause. The skin becomes itchy, red, and swollen and it may feel hot, burning, and tender. Chilblains usually resolve in 1 to 2 weeks, but they can come back. Keeping the extremities warm can help prevent them. If the hands and feet become cold, warm them slowly, as too much heat can cause further damage.

If symptoms worsen and blood supply is substantially reduced for a long time, fingers and toes can become deformed.

If oxygen is completely cut off from the area, skin ulcers and gangrenous tissue can develop. Both of these complications are difficult to treat. They may eventually require amputation.

[atlxolotl]

A new study has found that not sticking to a regular bedtime and wakeup schedule—and getting different amounts of sleep each night—can put a person at higher risk for obesity, high cholesterol, hypertension, high blood sugar and other metabolic disorders. In fact, for every hour of variability in time to bed and time asleep, a person may have up to a 27% greater chance of experiencing a metabolic abnormality.