#NHLBI

[pandemic-info]

A protein that disrupts cells’ energy centers may be a culprit in chronic fatigue syndrome | Science | AAAS

New study offers clues as to how exhaustion could arise in people with ME/CFS—and potentially related conditions such as Long Covid

People living with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) struggle not only with extreme exhaustion and the cognitive problems known as brain fog, but with a profound lack of information about what causes their symptoms and how to treat them. Scientists have yet to pin down the biology underlying the condition, which affects up to 2.5 million people in the United States alone, according to some estimates.

Now, researchers have identified a protein that’s present at unusually high levels in the muscles of people with ME/CFS and that disrupts cells’ ability to generate energy. The findings, reported today in the Proceedings of the National Academy of Sciences, could point to new therapeutics for this condition and for illnesses that share similar characteristics, such as Long Covid.

Akiko Iwasaki, an immunobiologist at Yale School of Medicine who was not involved in the work, praises the research as “very well done” but cautions that the suspect protein is likely “a piece of the puzzle, as opposed to explaining the whole disease.” The findings suggest it could act as one of several “middlemen” between whatever sparks the illness and symptoms such as fatigue, she says.

...

The NHLBI researchers wondered whether WASF3 was interacting with mitochondria, cellular compartments responsible for energy generation that have been suggested to malfunction in people with ME/CFS and Long Covid. Sure enough, by changing levels of WASF3 inside cultured cells from S1 as well as in other human and mouse cells, the team found  the protein could disrupt mitochondrial function. Specifically, high levels of WASF3 interfered with the assembly of mitochondrial proteins into molecular complexes that support normal energy production.

[drpedi07]

Body Mass Index (BMI) Calculator

Body mass index (BMI) is a measure of body fat based on height and weight that applies to adult men and women.

[covid-safer-hotties]

Also preserved in our archive

New research indicates that people who contracted COVID-19 early in the pandemic faced a significantly elevated risk of heart attack, stroke, and death for up to three years post-infection.

Those with severe cases saw nearly quadruple the risk, especially in individuals with A, B, or AB blood types, while blood type O was associated with lower risk. This finding highlights long-term cardiovascular threats for COVID-19 patients and suggests that severe cases may need to be considered as a new cardiovascular risk factor. However, further studies on more diverse populations and vaccinated individuals are needed to validate these results.

Long-Term Cardiovascular Risks Linked to COVID-19 Infection A recent study supported by the National Institutes of Health (NIH) found that COVID-19 infection significantly increased the risk of heart attack, stroke, and death for up to three years in unvaccinated people who contracted the virus early in the pandemic. This risk was observed in individuals with and without pre-existing heart conditions and confirms earlier research linking COVID-19 infection to a higher chance of cardiovascular events. However, this study is the first to indicate that the heightened risk may last as long as three years, especially for those infected during the first wave of the pandemic.

The study, published in the journal Arteriosclerosis, Thrombosis, and Vascular Biology, revealed that individuals who had COVID-19 early in the pandemic were twice as likely to experience cardiovascular events compared to those with no history of infection. For those with severe cases, the risk was nearly quadrupled.

“This study sheds new light on the potential long-term cardiovascular effects of COVID-19, a still-looming public health threat,” said David Goff, M.D., Ph.D., director for the Division of Cardiovascular Sciences at NIH’s National Heart, Lung, and Blood Institute (NHLBI), which largely funded the study. “These results, especially if confirmed by longer term follow-up, support efforts to identify effective heart disease prevention strategies for patients who’ve had severe COVID-19. But more studies are needed to demonstrate effectiveness.”

Genetic Factors and Blood Type’s Role in COVID-19 Complications The study is also the first to show that an increased risk of heart attack and stroke in patients with severe COVID-19 may have a genetic component involving blood type. Researchers found that hospitalization for COVID-19 more than doubled the risk of heart attack or stroke among patients with A, B, or AB blood types, but not in patients with O types, which seemed to be associated with a lower risk of severe COVID-19.

Scientists studied data from 10,000 people enrolled in the UK Biobank, a large biomedical database of European patients. Patients were ages 40 to 69 at the time of enrollment and included 8,000 who had tested positive for the COVID-19 virus and 2,000 who were hospitalized with severe COVID-19 between Feb. 1, 2020, and Dec. 31, 2020. None of the patients had been vaccinated, as vaccines were not available during that period.

The researchers compared the two COVID-19 subgroups to a group of nearly 218,000 people who did not have the condition. They then tracked the patients from the time of their COVID-19 diagnosis until the development of either heart attack, stroke, or death, up to nearly three years.

Higher Cardiovascular Risk in Patients With Severe Cases Accounting for patients who had pre-existing heart disease – about 11% in both groups – the researchers found that the risk of heart attack, stroke, and death was twice as high among all the COVID-19 patients and four times as high among those who had severe cases that required hospitalization, compared to those who had never been infected. The data further show that, within each of the three follow-up years, the risk of having a major cardiovascular event was still significantly elevated compared to the controls – in some cases, the researchers said, almost as high or even higher than having a known cardiovascular risk factor, such as Type 2 diabetes.

“Given that more than 1 billion people worldwide have already experienced COVID-19 infection, the implications for global heart health are significant,” said study leader Hooman Allayee, Ph.D., a professor of population and public health sciences at the University of Southern California Keck School of Medicine in Los Angeles. “The question now is whether or not severe COVID-19 should be considered another risk factor for cardiovascular disease, much like type 2 diabetes or peripheral artery disease, where treatment focused on cardiovascular disease prevention may be valuable.”

Allayee notes that the findings apply mainly to people who were infected early in the pandemic. It is unclear whether the risk of cardiovascular disease is persistent or may be persistent for people who have had severe COVID-19 more recently (from 2021 to the present).

Need for Broader Studies and Vaccine Impact on Risks Scientists state that the study was limited due to the inclusion of patients from only the UK Biobank, a group that is mostly white. Whether the results will differ in a population with more racial and ethnic diversity is unclear and awaits further study. As the study participants were unvaccinated, future studies will be needed to determine whether vaccines influence cardiovascular risk. Studies on the connection between blood type and COVID-19 infection are also needed as the mechanism for the gene-virus interaction remains unclear.

Study link: www.ahajournals.org/doi/10.1161/ATVBAHA.124.321001

[kennak]

妊娠前および妊娠初期中の肥満は、将来心血管疾患を発症するリスクの強力な指標であるようで、高血圧、子癇前症、妊娠糖尿病などの妊娠中の有害転帰と有意に関連していたという Circulation Research誌 。リンクは外部です） は、国立衛生研究所によって資金提供されました。 研究者らは、肥満が血圧に関連する心血管疾患や妊娠合併症の危険因子であることを知っています。 しかし、肥満と妊娠合併症のどちらが、妊娠後何年も経った人の心血管疾患のリスクに大きな影響を与えるかどうかはわかっていませんでした。 有害な妊娠転帰は妊娠中の心血管疾患リスクの増加と関連しているが、肥満患者の妊娠後数年間における心血管疾患リスクの増加のうち、合併症が占める割合はわずかであった。 「特定の妊娠合併症が明らかになり、すでに存在していた肥満などの心血管疾患のリスクが増大していることがわかっています。 この研究は、妊娠を考えている過体重または肥満の人に対する潜在的な介入のタイミングについての洞察を提供します」と、研究著者であり国立 ビ���トリア・L・ペンバ��トン 心臓・肺・血液心臓血管科学部門の研究者である （RNC）は述べた。研究所 (NHLBI)、NIH の一部。 研究者らは、 nuMoM2b心臓健康調査 （リンクは外部） 4,200人以上の初産婦を対象とした から収集したデータを分析した。そのうち約半数は過体重または肥満だった。 彼らは、参加者の妊娠経験と2～7年後の健康状態を比較した。 研究者らは、妊娠初期に過体重または肥満だった母親は、正常体重の参加者に比べて、妊娠糖尿病を発症したり、高血圧を合併した妊娠をするリスクが約2倍であることを発見した。 これらの母親は、妊娠後に心血管疾患を発症するリスクも増加していました。

妊娠合併症は肥満者の短期的および長期的な心血管リスクを増加させ、そのリスクを明らかにします | 国立衛生研究所 (NIH)

[molsons112000]

This is another reason why people don't survive from c p r. Because you're not doing the chest compressions, fast enough to supply the blood to the brain with enough continuous oxygen. So what happens is hypoxia sets in the brain cells start dying.... 🤔 it's better than nothing, but if you're going to do it, do it right!!!

And yes, warm breaths are better. Then the bag, because if it's cold air, it's harder for it to enter the lungs. That's why paramedics putting on oxygen mask.Don't work so well...

Cold temperatures cause our blood vessels to constrict. As a result, our blood circulation becomes poor which limits the availability of oxygen to many parts of the body. Your heart then has to work extra hard to pump blood.

https://portal.ct.gov › heatinghelp

Cold Weather and Our Health | Connecticut - CT.gov

While the air itself still contains the same percentage of oxygen when cold, it can be harder to get oxygen into your blood when the air is cold because cold air causes your airways to constrict, making it more difficult to inhale a sufficient amount of air, and can also lead to decreased blood circulation due to constricted blood vessels in response to the cold.

Key points to consider:

Physiological response:

When you breathe in cold air, your body tries to warm it up by constricting the airways in your lungs, which can limit the amount of oxygen reaching your bloodstream.

Blood circulation:

Cold temperatures also cause blood vessels to constrict, reducing blood flow to your lungs and potentially limiting the oxygen uptake.

Impact on certain individuals:

People with pre-existing lung conditions like asthma might experience more severe symptoms when breathing cold air due to airway sensitivity.

nhlbi, nih (.gov)

How the Lungs Work - The Respiratory System | NHLBI, NIH

Mar 24, 2022 — Airways * The airways are pipes that carry oxygen-rich air to the alveoli in your lungs. They also carry the waste gas carbon dioxide out of your l...

So it's important to have good circulation in the body and being active... but also keeping yourself properly clothed....

This is why people of color get plaque buildup in their arteries and in their brain in the winter... because their tissue is more sensitive, and so they tend to get lower levels of oxygen into the body, and this causes plaque build up and circulatory, as well as the brain..

Oh, as you see here, continuous hypoxia can promote arteriosclerosis and one of the other leaders of hypoxia is stress!!!

National Institutes of Health (NIH) (.gov)

https://www.ncbi.nlm.nih.gov › pmc

Continuous Hypobaric Hypoxia may Promote Atherosclerosis ...

by S Luo · 2023 · Cited by 4 — ... hypoxia may stimulate the degradation of collagen and consequently cause plaque instability. In the

Here you see hypoxia, being linked to plaque, buildup in the brain in alzheimer's!!!

National Institutes of Health (NIH) (.gov)

https://www.ncbi.nlm.nih.gov › pmc

What are the links between hypoxia and Alzheimer's disease? - PMC

by R Lall · 2019 · Cited by 64 — Association studies have recently showed that cerebral hypoxia, via both genetic and epigenetic

EMBO Press

https://www.embopress.org › doi

ER stress‐regulated translation increases tolerance to extreme ...

by M Bi · 2005 · Cited by 923 — An immediate reaction to hypoxia is a reduction in the rates of global protein synthesis that is thought to reduce

See your tailgating of me is causing continuous stress continuous stress causes hypoxia, continuous hypoxia. Causes plaque to build up in the arteries and lungs, you are killing me!!! You put me under financial stress. You put me on their stress from loneliness. You put me under stress when I go outside from tailgating.You put me under stress in unbelievable amounts of ways.You are killing me, killing me, killing me and killing me!!!!

Yes, stress can cause low levels of blood oxygen because when stressed, people tend to breathe shallowly, which doesn't effectively deliver enough oxygen to the blood, leading to a potential drop in blood oxygen saturation; this is often linked to the body's "fight or flight" response.

Key points about stress and oxygen levels:

Shallow breathing:

Under stress, people often breathe rapidly but shallowly, not fully filling their lungs and limiting oxygen intake.

Hyperventilation:

In some cases, high stress can lead to hyperventilation, which involves rapid, deep breaths that can also cause low blood oxygen levels due to the body expelling too much carbon dioxide.

Physiological response:

The stress response activates the sympathetic nervous system, which can affect breathing patterns and contribute to lower oxygen levels.

What can be done:

Mindful breathing:

Practicing deep, conscious breaths can help counteract the effects of stress on breathing and maintain adequate oxygen levels.

Relaxation techniques:

Yoga, meditation, and other relaxation practices can help manage stress and promote better breathing patterns.

Psych Central

Can Stress Cause Low Oxygen Levels? - Psych Central

Aug 12, 2022 — Stress can affect your body and mind and may leave you feeling short of breath. When there isn't enough oxygen being passed through your blood, your...

When you get stressed, you start to breathe faster yet less efficiently than normal. Those shallow breaths don't do a good job at sending oxygen to your blood. Instead those shallow breaths lower your oxygen levels, triggering you to breathe faster in order to get the level of oxygen your body needs.

https://precisionmedical.com › stre...

Stress and Oxygen Therapy - Precision Medical, Inc.

This is why people in the military, because they don't do things correctly with treating them and lowering stress in non combat situations that they cause buildups of plaque in the arteries and brain...

Yes, there is a link between stress and Alzheimer's disease:

Stress affects the immune system

The immune system plays an important role in dementia development, and stress can impact it.

Cortisol levels

When you're stressed, your body releases cortisol, a hormone that's been linked to memory problems. High levels of cortisol are associated with Alzheimer's disease.

Stress-related disorders

People with a history of stress-related disorders, such as PTSD or adjustment disorder, have an increased risk of dementia.

Accelerates disease progression

Stress can speed up the progression of Alzheimer's disease, including the formation of amyloid plaque and tau tangles.

Increases risk of cognitive impairment

Chronic stress increases the risk of mild cognitive impairment.

Additive effect with depression

The risk of Alzheimer's disease and mild cognitive impairment may be increased even more when chronic stress and depression are combined.

The majority of Alzheimer's cases have no known genetic cause, so environmental factors like stress are thought to play an important role.

Alzheimer's Society

Can stress cause dementia? | Alzheimer's Society

May 21, 2024

In summary, stress alone is a not a key factor in the onset of Alzheimer's disease; however, it may be important in the progression of the disease, as well as …

https://www.news-medical.net › St...

Stress and Alzheimer's Disease - News-Medical

Patients with stress-related disorders showed the highest and significantly increased risk for Alzheimer's dementia (HR = 1.22, 95% CI 1.04–1.56).Oct 1, 2023

https://www.nature.com › articles

Association between stress-related disorders and the ...

Veterans living with post-traumatic stress disorder (PTSD) or traumatic brain injury (TBI) have a higher risk of developing dementia or Alzheimer's. The Alzheimer's Association has information and resources to answer your questions about veterans and dementia risk, symptoms and treatment.

https://www.alz.org › resources › ve...

Veterans and Dementia - Alzheimer's Association

Yes, military personnel are more likely to develop Alzheimer's disease than the general population:

Traumatic brain injury (TBI)

TBIs can affect cognitive abilities like learning and thinking. Veterans of recent wars have experienced more serious head injuries than ever before.

Post-traumatic stress disorder (PTSD)

PTSD is a chronic anxiety disorder that can make it difficult to recover from traumatic events. People with PTSD are almost twice as likely to develop dementia.

Exposure to blasts

Shockwaves from military explosives can alter the connections between neurons in the hippocampus, which is involved in memory encoding.

Other factors

Veterans may also be at an increased risk due to their age, demographics, and socioeconomic factors.

The Alzheimer's research community is focusing on identifying individuals at high risk and preventing disease in its early stages.

NCBI

Military risk factors for Alzheimer's disease - PMC - NCBI

Mounting evidence suggests that traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD) resulting from military exposures increase the risk of de...

See, remember, this is stressed. Induced stress causes hypoxia and stress on a continuous basis causes plaque to build up in the arteries, causing culinary artery disease. Like in my father and he died of a mass of heart attack! My father was in the military and then under continuous stress!!!

Cardiovascular disease (CVD) is the leading cause of death in the United States among both men and women, accounting for 1 in every 4 deaths annually. The active duty component of the US Army (hereafter, “Army”) is afflicted more by CVD than by any other chronic disease.Jun 5, 2019

https://www.ahajournals.org › doi

Comparison of Cardiovascular Health Between US Army and ...

Yes, military personnel are more likely to have coronary artery disease (CAD) than civilians:

Combat deployments

Young service members and veterans who reported combat experiences had almost twice the odds of developing new-onset CAD than those without combat exposure.

Cardiovascular health

A study found that active-duty Army personnel had worse cardiovascular health than civilians of similar ages.

Veteran status

Veterans have a higher risk of having CAD than non-veterans. Male veterans are at an even higher risk than female veterans.

Other risk factors for CAD include:

Diabetes

Hyperlipidemia

Smoking

Hypertension

Family history of CAD

Chronic noise exposure

NCBI

Assessment of risk factors for coronary artery disease in ...

Results: Data analysis indicated that the risk factors including diabetes, hyperlipidemia, smoking, hypertension, and positive family history of CAD enhance the...

So I watched this piece of s***Federal government piece of garbage state piece of garbage county and local governments allow people to drive inappropriately, allow people to act inappropriately in all environments, causing massive stress, destroying us internally and externally!!!

So I noticed this with my first breakdown, the chronic stress caused me to get toe fungus, and then it caused me to get warts, and these are all signs of immense stress, and then they cause you to get different skin issues, and then that chronic stress causes chronic hypaxia, chronic. Hypaxia causes parkinson's!!!

Yes, chronic stress can cause a variety of skin problems, including:

Acne: Stress can make acne worse by causing the body to produce more oil.

Psoriasis and eczema: Stress can trigger flare-ups of these skin conditions.

Rosacea: Stress can trigger this inflammatory condition, which causes redness and visible blood vessels on the face.

Hives: Stress can trigger chronic urticaria, also known as hives.

Vitiligo: Stress can weaken the immune system, making the body more vulnerable to autoimmune diseases like vitiligo, which causes loss of skin color.

Hair loss: Stress can contribute to hair thinning and loss.

Wrinkles: Stress hormones break down collagen and elastin in the skin, which can speed up the aging process and cause more wrinkles.

Stress can also impair the skin's ability to heal wounds.

To treat stress-related skin issues, you can:

Manage stress

Try to reduce stress through lifestyle changes like getting enough sleep, exercising regularly, eating well, meditating, and spending time with friends and loved ones. You can also consider talking to a therapist or other mental health professional.

Practice good skincare

Wash your face with a gentle cleanser, use sunscreen regularly, and keep your skin moisturized.

Stress rashes usually go away on their own, but you should contact a doctor if you suspect your hives are an allergic reaction.

Bupa UK

Does stress cause skin problems? - Bupa UK

Ongoing stress can also weaken your immune system. This makes you more vulnerable to infection and skin diseases like vitiligo (loss of skin colour) and chronic...

Yes, hypoxia, or low oxygen supply, may be a factor in the development of Parkinson's disease (PD):

Case studies

Some case studies have shown that exposure to hypoxia can trigger Parkinsonian symptoms, such as tremors, limb rigidity, and gait disturbances.

Research

Research suggests that hypoxia may be linked to the pathology of PD by increasing the expression and aggregation of alpha-synuclein (α-syn), a protein that is pathogenic in PD.

Hypoxia conditioning

Some research suggests that mild hypoxia can have neuroprotective effects, and that this could be a potential therapeutic strategy for PD.

PD is a neurodegenerative disorder that causes the death of dopamine-producing neurons, which leads to movement problems. The exact cause of this neuronal loss is unknown, but it may be linked to environmental factors, genetics, and molecular pathways.

NCBI

Hypoxia Signaling in Parkinson's Disease: There Is Use in Asking ...

Jul 29, 2021 — Parkinson's disease is a neurodegenerative disorder characterized by the death of a specific subset of dopamine-producing neurons. This triggers pro...

Although stress does not directly cause vertigo, it can trigger symptoms. Vertigo results from a dysfunction in the vestibular system. The vestibular system helps people maintain their balance and starts in their ears. Tiny hairs in the inner ear detect head movements and send messages to the brain.Jan 15, 2024

https://www.medicalnewstoday.com › ...

Vertigo and stress: Is there a link? - MedicalNewsToday

Stress doesn't directly cause vertigo, but it can trigger or worsen symptoms. Stress can affect the vestibular system, which controls balance, in several ways, including:

Hormones

Stress hormones like cortisol can impact the nervous system.

Muscle tension

Anxiety can cause muscles to tense up, making it harder for blood to reach the brain and inner ear.

Brain activity

The brain areas responsible for balance and stress are connected, so activity in one area can impact the other.

Immune system

Stress can weaken the immune system, which can lead to viral overload and viral vertigo.

Some people with anxiety disorders experience vertigo more often. For example, someone with social anxiety might feel dizzy when in a crowded room.

To prevent vertigo caused by stress, you can try: Managing stress with coping skills like deep breathing and mindfulness, Maintaining a regular sleep schedule, Eating a balanced diet, and Exercising more.

If you're experiencing vertigo and stress, you can talk to a healthcare professional to learn about treatments.

Healthline

Can Stress Cause Vertigo? Risk Factors, Treatment, and Prevention

Oct 8, 2020

Hey These are signs that psychologists need to understand that stress anxiety causes wartz... See, they have to be good therapist. It also causes extreme weight, gain or extreme Weight loss These are all signs of psychological stress!!!!

Yes, stress can cause warts by weakening the immune system's ability to fight off viruses like HPV, which causes warts:

How stress causes warts

Stress causes the release of hormones that build up over time, weakening the immune system.

Other risk factors

Other factors that can increase the risk of getting warts include having a weak immune system, being sexually active, or having hormonal disorders.

How HPV is spread

HPV is spread through skin-to-skin contact, shaking hands, turning doorknobs, typing on keyboards used by many, or sharing common shoes or towels.

How warts appear

HPV causes too much keratin to develop in the top layer of skin, which produces the rough, hard texture of a wart.

How warts can affect self-esteem

Warts can affect a patient's self-esteem and confidence, and sometimes make them feel stigmatized in certain social situations.

How to get rid of warts

Over-the-counter options like salicylic acid gel, liquid, or pads can help get rid of warts. You can also try covering the area with duct tape after applying salicylic acid, then soaking the area in water after removing the duct tape.

Some studies show that people with warts have lower B12 levels, and that zinc can help improve and clear warts.

The Economic Times

warts: What causes warts, how are they transmitted, and how to get rid of them? - The Economic Times

Apr 24, 2023

So I told you, I got warts, and I got tofungus continuous, because of continuous stress from my first now second breakdown...

Yes, stress can contribute to toe fungus in a number of ways:

Sweating

Stress can impact your sweat patterns, leading to excess moisture on your feet. This can cause skin texture issues, which can lead to corns and friction between your toes.

Weakened immune system

Stress can weaken your immune system, making you more susceptible to fungal infections.

Self-inflicted habits

People who are stressed or nervous may develop habits or tics that can lead to skin, hair, or nail problems.

Other factors that can increase your risk of toenail fungus include:

Being older

Having a family history of fungal infections

Having a weakened immune system

Having circulation issues

Wearing tight-fitting shoes

Walking barefoot in damp public places

Having a previous injury or infection to the skin or nail

Fungal infections are caused by microscopic organisms called fungi, which can enter your skin or nail through cracks or splits. You can pick up the fungi from skin-to-skin contact with someone who has a fungal infection, or by breathing in fungus from the environment.

Errol Gindi, DPM

What Causes Toenail Fungus? - Errol Gindi, DPM

What is toenail fungus? Fungal infections occur when yeasts or molds that exist in the environment around you enter your nail or the skin of your toes, typicall...

So the government flooded the country in with refugees, legal and illegal immigration that cause unbelievable amounts of stress related to that the sixties got more violent, the seventies were the most violent decade ever and violent crimes have been through the roof ever since!!! 😳 you can't flood people into the country. They must undergo significant educational process before they can be released into the country. Training them to understand what is culturally appropriate in the united states, so they fit in correctly!!!!!!

And you wonder why God said what he did that people that did this to me the first time he predicted it coming on, and then he predicted it the second time he would do it to me. N the second time he said, if they do it to you again, then i'm going to condemn them all!!!! And you did it to me again? And you constantly put me in the situations of incredible stress unbelievably destroying me!!!

But again, this is for therapists to understand and i'm communicating this the crete awareness, because facebook constantly says I go against the community, facebook goes against a community.I believe it's being run by demons now!!!!

Yes, chronic stress can indeed lead to both extreme weight gain and weight loss, primarily due to its impact on hormone levels, particularly cortisol, which can significantly alter appetite and metabolism, causing individuals to either overeat or lose interest in food depending on the situation.

How stress can cause weight gain:

Increased cortisol levels:

When stressed, the body releases cortisol, which can stimulate appetite and cravings for high-calorie foods, leading to overeating and fat storage, especially around the abdomen.

Disrupted eating patterns:

Stress can lead to irregular meal times, skipping meals, and emotional eating, contributing to unhealthy dietary choices.

Slowed metabolism:

Chronic stress can affect metabolic rate, making it harder to burn calories.

How stress can cause weight loss:

Decreased appetite:

In some cases, high stress can suppress appetite, leading to reduced calorie intake and potential weight loss.

Digestive issues:

Stress can disrupt digestion, leading to malabsorption of nutrients and weight loss.

Sleep disturbances:

Stress often disrupts sleep patterns, which can further impact hormone regulation and metabolism, contributing to weight loss.

Important points to remember:

Individual variations:

The relationship between stress and weight can vary significantly between individuals, depending on their stress response, eating habits, and lifestyle.

Managing stress is key:

To prevent stress-related weight changes, managing stress through techniques like exercise, relaxation practices, and mindfulness is crucial.

WebMD

Surprising Reasons You're Gaining Weight

Jun 1, 2024 — When life's demands get too intense, our bodies go into survival mode. Cortisol, the "stress hormone," is secreted, which causes an increase in appet...

But I also point this out so everybody can understand how these issues affect you. So doctors can mitigate these situations, so these extreme negative conditions don't happen to people, whether you're white or of color meaning darker color than white!!!!!

[rodspurethoughts]

Guard Against COPD at Every Stage of Life

(Family Features) Take a deep breath. Now ask yourself: When was the last time you thought about breathing? For people with chronic obstructive pulmonary disease (COPD), breathing is often front of mind because it can be difficult, and it gets worse over time. Dealing with COPD There is no cure yet for COPD, but experts from the National Heart, Lung, and Blood Institute (NHLBI) recommend these…

[leedsomics]

Genetic Architecture and Analysis Practices of Circulating Metabolites in the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program

Circulating metabolite levels partly reflect the state of human health and diseases, and can be impacted by genetic determinants. Hundreds of loci associated with circulating metabolites have been identified; however, most findings focus on predominantly European ancestry or single study analyses. Leveraging the rich metabolomics resources generated by the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program, we harmonized and accessibly cataloged 1,729 circulating metabolites among 25,058 ancestrally-diverse samples. We provided recommendations for outlier and imputation handling to process metabolite data, as well as a general analytical framework. We further performed a pooled analysis following our practical recommendations and discovered 1,778 independent loci associated with 667 metabolites. Among 108 novel locus-metabolite pairs, we detected not only novel loci within previously implicated metabolite associated genes, but also novel genes (such as GAB3 and VSIG4 located in the X chromosome) that have putative roles in metabolic regulation. In the sex-stratified analysis, we revealed 85 independent locus-metabolite pairs with evidence of sexual dimorphism, including well-known metabolic genes such as FADS2, D2HGDH, SUGP1, UTG2B17, strongly supporting the importance of exploring sex difference in the human metabolome. Taken together, our study depicted the genetic contribution to circulating metabolite levels, providing additional insight into the understanding of human health. http://dlvr.it/TB2sNn

[dr-smita-goel-homeopathy-clinic]

*Dr. Smita Goel Homeopathy Clinic*

www.thehomeopathyclinic.co.in

A person with Raynaud's disease experiences pain in the extremities, for example, the fingers, when temperatures drop.

Blood vessels narrow and almost completely shut down. Fingers or toes turn from white to blue and, then, as the blood returns, they flush red.

Also known as Raynaud's syndrome or Raynaud's phenomenon, As per research females are an estimated nine times more likely to be affected than males.

Fast facts on Raynaud's disease are followings:

• Raynaud's disease is caused by peripheral blood vessels overreacting to cold.

• Maurice Raynaud first described the disease in 1862.

• Females and people living in colder climates are more often affected.

• A capillaroscopy can help diagnose Raynaud's disease.

Living with Raynaud's

People who are prone to Raynaud's can take measures to avoid some triggers.

The National Heart, Lung, and Blood Institute (NHLBI) suggest:

• wrapping up and keeping the house warm when temperatures are cold

• as far as possible, avoiding emotional stress

• exercise to promote a healthy lifestyle and reduce stress

• avoiding medicines and substances that trigger the symptoms

• limiting consumption of caffeine and alcohol

• not smoking

Homeopathy has good treatment for it. Getting medical help may prevent a worsening of symptoms and serious complications.

Causes

Exactly what causes Raynaud's remains unclear, but a hyperactivation of the sympathetic nervous system is known to cause an extreme narrowing of the blood vessels, known as vasoconstriction.

It can happen when the person enters a cold place, opens a freezer, or puts their hands in cold water.

Some people experience symptoms when faced with stress, even without an associated drop in temperature.

In healthy individuals, the circulatory system in the extremities, such as the fingers and toes, reacts to conserve heat in cold conditions. The small arteries that supply the skin with oxygen narrow to minimize the amount of heat lost through the exposed skin surface.

In people with Raynaud's disease, this narrowing is excessive. This is what causes the blood vessels almost to shut down.

Types

There are two types of Raynaud's disease: Primary and secondary.

Primary Raynaud's, or Raynaud's disease, is more common, and it affects people who do not have a secondary medical condition.

Secondary Raynaud's, or Raynaud's phenomenon or syndrome, results from an underlying medical issue. It is less common and tends to be more serious.

Causes of secondary Raynaud's

Causes of secondary Raynaud's include:

Diseases of the arteries: Atherosclerosis, a build-up of plaque in blood vessels, or Buerger's syndrome, a disorder where blood vessels in the hands and feet become inflamed, can cause Raynaud's symptoms. Primary pulmonary hypertension has also been linked to the disease.

Diseases of the connective tissue: Most people with scleroderma, a disease leading to hardened skin, have Raynaud's disease. The symptoms are commonly linked to lupus, rheumatoid arthritis, and Sjogren's syndrome, an autoimmune disease affecting glands.

Repetition or vibration: People whose hobbies or jobs require repetitive movements, such as typing or playing the guitar or piano, are at risk of developing Raynaud's symptoms. Those whose jobs involve using vibrating tools, such as a jackhammer, are also at risk.

Carpal tunnel syndrome: This condition puts pressure on the nerves traveling to the hand, and it increases susceptibility to Raynaud's symptoms.

Medications: Drugs that can induce Raynaud's include beta blockers, migraine medications containing ergotamine or sumatriptan, ADHD medications, some chemotherapy drugs, and some over-the-counter cold remedies.

Exposure to certain substances: Smoking narrows blood vessels and is a possible cause of Raynaud's. Other chemicals, such as vinyl chloride, may also play a role.

Injuries: Raynaud's can start after injuries such as frostbite, a broken wrist, or local surgery.

Raynaud's tends to affect females more than males. Primary Raynaud's normally starts between the ages of 15 years and 25 years, and secondary Raynaud's between 35 and 40 years.

The condition appears to run in families. A person a first-degree relative with Raynaud's is more likely to develop it.

Possible pathways of Raynaud's disease

The exact pathways of Raynaud's disease are not known, but it probably results from a combination of factors, and the combination of factors probably differs between individuals.

Other possibilities

Platelet activation appears to be higher in people with Raynaud's. Platelets are components in blood that clump together to help prevent bleeding.

Fibrinolysis is a natural reaction that takes place in the body to reduce clotting. Some studies have linked low levels of fibrinolysis with Raynaud's.

Oxidative stress is caused by an increase in free radicals, and it could be involved in Raynaud's.

Symptoms

Raynaud's disease causes blood vessels in the hands or feet to overreact to the cold, causing numbness and pain.

Raynaud's disease affects some people when they are exposed to the cold.

When temperatures drop, the blood vessels contract in the fingers or toes. This contraction causes hypoxia, or lack of oxygen, to the affected tissues. Fingers and toes will feel cold to the touch and possibly numb.

Often, the affected area will turn white, then later turn blue. Once the area is warmed and blood flow returns, a tingling sensation may accompany a red flush and, possibly, swelling. There may also be a painful, throbbing sensation.

Toes and fingers are most commonly affected, but Raynaud's can affect the nose, lips, and ears.

Some women may experience Raynaud's phenomenon of the nipples, especially during breastfeeding. It causes severe throbbing, similar to that experienced with a fungal Candida albicans infection, which can lead to misdiagnosis.

An episode normally lasts around 15 minutes, including the time it takes for the body to normalize.

Raynaud's feet

Raynaud's syndrome can affect either the hands or feet, or both.

To reduce the risk of an attack, it can help to keep the feet and hands warm, avoid smoking, and get enough exercise.

If an attack starts, it may be reduced or prevented by warming the hands and feet at once, for example, by massaging them.

The feet and hands should be protected from cuts, bruises, and other injuries as far as possible, because the lack of circulation can make it harder for them to heal. Use lotion to prevent the skin from cracking, and make sure you have comfortable, well-fitting shoes.

Complications

Raynaud's is not normally life-threatening, but complications can occur.

Chilblains happen when there is a problem with the blood circulation, and Raynaud's is one possible cause. The skin becomes itchy, red, and swollen and it may feel hot, burning, and tender. Chilblains usually resolve in 1 to 2 weeks, but they can come back. Keeping the extremities warm can help prevent them. If the hands and feet become cold, warm them slowly, as too much heat can cause further damage.

If symptoms worsen and blood supply is substantially reduced for a long time, fingers and toes can become deformed.

If oxygen is completely cut off from the area, skin ulcers and gangrenous tissue can develop. Both of these complications are difficult to treat. They may eventually require amputation.

[covid-safer-hotties]

Also preserved on our archive

NIH-funded study focused on original virus strain, unvaccinated participants during pandemic.

Infection from COVID-19 appeared to significantly increase the risk of heart attack, stroke, and death for up to three years among unvaccinated people early in the pandemic when the original SARS-CoV-2 virus strain emerged, according to a National Institutes of Health (NIH)-supported study. The findings, among people with or without heart disease, confirm previous research showing an associated higher risk of cardiovascular events after a COVID-19 infection but are the first to suggest the heightened risk might last up to three years following initial infection, at least among people infected in the first wave of the pandemic.

Compared to people with no COVID-19 history, the study found those who developed COVID-19 early in the pandemic had double the risk for cardiovascular events, while those with severe cases had nearly four times the risk. The findings were published in the journal Arteriosclerosis, Thrombosis, and Vascular Biology.

“This study sheds new light on the potential long-term cardiovascular effects of COVID-19, a still-looming public health threat,” said David Goff, M.D., Ph.D., director for the Division of Cardiovascular Sciences at NIH’s National Heart, Lung, and Blood Institute (NHLBI), which largely funded the study. “These results, especially if confirmed by longer term follow-up, support efforts to identify effective heart disease prevention strategies for patients who’ve had severe COVID-19. But more studies are needed to demonstrate effectiveness.”

The study is also the first to show that increased risk of heart attack and stroke in patients with severe COVID-19 may have a genetic component involving blood type. Researchers found that hospitalization for COVID-19 more than doubled the risk of heart attack or stroke among patients with A, B, or AB blood types, but not in patients with O types, which seemed to be associated with a lower risk of severe COVID-19.

Scientists studied data from 10,000 people enrolled in the UK Biobank, a large biomedical database of European patients. Patients were ages 40 to 69 at the time of enrollment and included 8,000 who had tested positive for the COVID-19 virus and 2,000 who were hospitalized with severe COVID-19 between Feb. 1, 2020, and Dec. 31, 2020. None of the patients had been vaccinated, as vaccines were not available during that period.

The researchers compared the two COVID-19 subgroups to a group of nearly 218,000 people who did not have the condition. They then tracked the patients from the time of their COVID-19 diagnosis until the development of either heart attack, stroke, or death, up to nearly three years.

Accounting for patients who had pre-existing heart disease – about 11% in both groups – the researchers found that the risk of heart attack, stroke, and death was twice as high among all the COVID-19 patients and four times as high among those who had severe cases that required hospitalization, compared to those who had never been infected. The data further show that, within each of the three follow-up years, the risk of having a major cardiovascular event was still significantly elevated compared to the controls – in some cases, the researchers said, almost as high or even higher than having a known cardiovascular risk factor, such as Type 2 diabetes.

“Given that more than 1 billion people worldwide have already experienced COVID-19 infection, the implications for global heart health are significant,” said study leader Hooman Allayee, Ph.D., a professor of population and public health sciences at the University of Southern California Keck School of Medicine in Los Angeles. “The question now is whether or not severe COVID-19 should be considered another risk factor for cardiovascular disease, much like type 2 diabetes or peripheral artery disease, where treatment focused on cardiovascular disease prevention may be valuable.”

Allayee notes that the findings apply mainly to people who were infected early in the pandemic. It is unclear whether the risk of cardiovascular disease is persistent or may be persistent for people who have had severe COVID-19 more recently (from 2021 to the present).

Scientists state that the study was limited due to inclusion of patients from only the UK Biobank, a group that is mostly white. Whether the results will differ in a population with more racial and ethnic diversity is unclear and awaits further study. As the study participants were unvaccinated, future studies will be needed to determine whether vaccines influence cardiovascular risk. Studies on the connection between blood type and COVID-19 infection are also needed as the mechanism for the gene-virus interaction remains unclear.

This study was supported by NIH grants R01HL148110, R01HL168493, U54HL170326, R01DK132735, P01HL147823, R01HL147883, and P30ES007048.

About the National Heart, Lung, and Blood Institute (NHLBI): NHLBI is the global leader in conducting and supporting research in heart, lung, and blood diseases and sleep disorders that advances scientific knowledge, improves public health, and saves lives. For more information, visit www.nhlbi.nih.gov.

About the National Institutes of Health (NIH): NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit www.nih.gov.

NIH…Turning Discovery Into Health®

Study Allayee, H, et al. COVID-19 Is a Coronary Artery Disease Risk Equivalent and Exhibits a Genetic Interaction With ABO Blood Type(link is external). [2024] Arteriosclerosis, Thrombosis, and Vascular Biology. DOI: 10.1161/ATVBAHA.124.321001

[atlxolotl]

A new study has found that not sticking to a regular bedtime and wakeup schedule—and getting different amounts of sleep each night—can put a person at higher risk for obesity, high cholesterol, hypertension, high blood sugar and other metabolic disorders. In fact, for every hour of variability in time to bed and time asleep, a person may have up to a 27% greater chance of experiencing a metabolic abnormality.

[fresh-dr1nk]

Caused of High cholesterol

Overview Caused of High cholesterol: Cholesterol is a waxy substance present in your blood. Your physique wants cholesterol to construct wholesome cells, however excessive ranges of cholesterol can improve your danger of coronary heart illness. With excessive cholesterol, you may develop fatty deposits in your blood vessels. Eventually, these deposits develop, making it tough for sufficient blood to circulation via your arteries. Sometimes, these deposits can break all of a sudden and kind a clot that causes a coronary heart assault or stroke. High cholesterol could be inherited, nevertheless it's typically the results of unhealthy way of life selections, which make it preventable and treatable. A nutritious diet, common train and generally remedy might help cut back excessive cholesterol. Products & Services - The One Food Cholesterol Cure - Just drink Juice, lose weight Show extra merchandise from Mayo Clinic Symptoms High cholesterol has no signs. A blood check is the one solution to detect in case you have it. When to see a health care provider According to the National Heart, Lung, and Blood Institute (NHLBI), an individual's first cholesterol screening ought to happen between the ages of 9 and 11, after which be repeated each 5 years after that. The NHLBI recommends that cholesterol screenings happen each one to 2 years for males ages 45 to 65 and for girls ages 55 to 65. People over 65 ought to obtain cholesterol assessments yearly. If your check outcomes aren't inside fascinating ranges, your physician would possibly advocate more-frequent measurements. Your physician may also counsel more-frequent assessments in case you have a household historical past of excessive cholesterol, coronary heart illness or different danger elements, reminiscent of diabetes or hypertension. More Information - The One Food Cholesterol Cure From Mayo Clinic to your inbox Sign up without cost and keep updated on analysis developments, well being suggestions, present well being subjects, and experience on managing well being. EmailLearn extra about Mayo Clinic’s use of knowledge.Subscribe! Causes Cholesterol is carried via your blood, connected to proteins. This mixture of proteins and cholesterol is named a lipoprotein. There are various kinds of cholesterol, based mostly on what the lipoprotein carries. They are: - Low-density lipoprotein (LDL). LDL, the "bad" cholesterol, transports cholesterol particles all through your physique. LDL cholesterol builds up within the partitions of your arteries, making them onerous and slim. - High-density lipoprotein (HDL). HDL, the "good" cholesterol, picks up extra cholesterol and takes it again to your liver. A lipid profile additionally sometimes measures triglycerides, a kind of fats within the blood. Having a excessive triglyceride degree can also improve your danger of coronary heart illness. Related: High Cholesterol Cure Program Factors you may management — reminiscent of inactivity, weight problems and an unhealthy eating regimen — contribute to dangerous cholesterol and triglyceride ranges. Factors past your management would possibly play a job, too. For instance, your genetic make-up would possibly make it harder on your physique to take away LDL cholesterol out of your blood or break it down within the liver. Medical situations that may trigger unhealthy cholesterol ranges embrace: - Chronic kidney illness - Diabetes - HIV/AIDS - Hypothyroidism - Lupus Cholesterol ranges can be worsened by some forms of drugs it's possible you'll be taking for different well being issues, reminiscent of: - Acne - Cancer - High blood stress - HIV/AIDS - Irregular coronary heart rhythms - Organ transplants Related: Cholesterol of High Cure Program Risk elements Factors that may improve your danger of unhealthy cholesterol ranges embrace: - Poor eating regimen. Eating an excessive amount of saturated fats or trans fat can lead to unhealthy cholesterol ranges. Saturated fat are present in fatty cuts of meat and full-fat dairy merchandise. Trans fat are sometimes present in packaged snacks or desserts. - Obesity. Having a physique mass index (BMI) of 30 or better places you vulnerable to excessive cholesterol. - Lack of train. Exercise helps enhance your physique's HDL, the "good," cholesterol. - Smoking. Cigarette smoking could decrease your degree of HDL, the "good," cholesterol. - Alcohol. Drinking an excessive amount of alcohol can improve your complete cholesterol degree. - Age. Even younger youngsters can have unhealthy cholesterol, nevertheless it's way more frequent in folks over 40. As you age, your liver turns into much less in a position to take away LDL cholesterol. Complications High cholesterol could cause a harmful accumulation of cholesterol and different deposits on the partitions of your arteries (atherosclerosis). These deposits (plaques) can cut back blood circulation via your arteries, which may trigger problems, reminiscent of: - Chest ache. If the arteries that offer your coronary heart with blood (coronary arteries) are affected, you might need chest ache (angina) and different signs of coronary artery illness. - Heart assault. If plaques tear or rupture, a blood clot can kind on the plaque-rupture website — blocking the circulation of blood or breaking free and plugging an artery downstream. If blood circulation to a part of your coronary heart stops, you may have a coronary heart assault. - Stroke. Similar to a coronary heart assault, a stroke happens when a blood clot blocks blood circulation to a part of your mind. Related: High Cholesterol Cure Program Prevention The similar heart-healthy way of life modifications that may decrease your cholesterol might help forestall you from having excessive cholesterol within the first place. To assist forestall excessive cholesterol, you may: - Eat a low-salt eating regimen that emphasizes fruits, greens and entire grains - Limit the quantity of animal fat and use good fat sparsely - Lose additional kilos and preserve a wholesome weight - Quit smoking - Exercise on most days of the week for at the very least half-hour - Drink alcohol sparsely, if in any respect - Manage stress Other Posts that you might like! >> Obesity and Snoring: Unveiling the Hidden Link >> Fat Knees: 7 Steps to Healthier Knees from Knee Pain >> The Smoothie Diet 21-Day Program Reviews 2024 (Shocking Customer Results Exposed) on Recipe! MUST READ >> AquaBliss Shower Filter Effective for Hard Water? Read the full article

[blog-site-for-market-research]

Medical Oxygen Concentrators Market is Rising Rapidly in Coming Years

Market Overview –

The medical oxygen concentrators market focuses on devices designed to deliver oxygen therapy to patients with respiratory conditions. These devices concentrate oxygen from ambient air, providing a continuous and reliable source of oxygen for patients who require supplemental oxygen therapy. The market includes stationary and portable oxygen concentrators, as well as accessories such as nasal cannulas, oxygen masks, and tubing.

The medical oxygen concentrators market is witnessing rapid growth, especially in the segment of portable oxygen compressors. With an increasing emphasis on home healthcare, there's a surge in demand for convenient, lightweight concentrators. These portable devices offer patients greater mobility and independence while ensuring continuous oxygen therapy. This trend fuels market expansion and innovation in portable oxygen compressor technology.

The medical oxygen concentrators market was valued at USD 1.15 billion in 2021 and is expected to rise from USD 1.37 billion in 2022 to USD 4.80 billion by 2030, with a compound annual growth rate (CAGR) of 5.90% during the forecast period (2022- 2030).

Advancements in technology have led to the development of more efficient, lightweight, and portable oxygen concentrators, offering greater mobility and flexibility for patients. These devices allow patients to maintain their oxygen therapy regimen while engaging in daily activities, traveling, or receiving care in non-hospital settings.

The COVID-19 pandemic has underscored the importance of medical oxygen concentrators in managing respiratory complications associated with severe COVID-19 infection. The pandemic has led to increased demand for oxygen therapy devices, particularly in regions experiencing surges in COVID-19 cases, prompting healthcare facilities to invest in additional equipment and expand their oxygen supply capacity.

Market Drivers and Restraints

There has been an unusual increase in the demand for ventilators since the COVID-19 outbreak, leading to a considerable shortage worldwide. Ventilators’ unmet demand has compelled scientists and engineers to make makeshift ventilators with the use of respiratory equipment like oxygen concentrators, manual resuscitators, PAP, nebulizers, and more. This has been quite pivotal for the oxygen concentrators market, in terms of growth. Apart from the rising cases of SARS-CoV-2 despite the strict lockdown, COPDs/Chronic Obstructive Pulmonary Diseases have also surged significantly in recent years, which bolster the need for oxygen concentrators. Experts believe that despite the grave impact of the novel coronavirus and the rapid escalation of the pandemic, the global market can observe sustained growth due to the rise in technological innovations and the subsequent miniaturization of medical oxygen concentrators across the globe.

Governments and non-government agencies are proactively setting up programs and campaigns to make more citizens aware about asthma and COPD and the available treatment options. For example, NHLBI/National Heart, Lung, and Blood Institute along with WHO, created GOLD or Global Initiative for Chronic Obstructive Lung Disease to raise the awareness level regarding COPD. With the growing number of pandemics like SARS and COVID-19 in the past couple of years, the need for artificial or makeshift ventilators has soared, specifically for piped/canned and wall-mounted oxygen concentrators.

Furthermore, manufacturers are coming up with innovative technologies that aim to elevate the quality of healthcare. Companies are also entering agreements and collaborations to bolster their manufacturing capacity to meet with the soaring demand for oxygen concentrators in the global market. For instance, in October 2020, ZOLL Medical Corporation, a medical devices manufacturer, and CAIRE Inc., a renowned oxygen supply vendor, entered a distributor agreement. The agreement entails ZOLL getting the rights for the distribution of CAIRE’s SAROS 4000 Portable Oxygen Concentrators outside the United States.

Market Segmentation

Medical Oxygen Concentrators market can be split into product, technology, indication and end user.

The key products listed in the market study are stationary oxygen concentrators as well as portable oxygen concentrators. As of 2018, the portable oxygen concentrators segment has remained in the lead and can continue to do so throughout the given period due to the surging uptake by travelers as these are lightweight, compact, offer higher oxygen capacity and mobility. Stationary oxygen concentrators segment on the other hand, can record a better growth rate as these provide a relatively more stable oxygen source along with a hands-free provision as well as longer tubing.

Some of the top technologies considered in the study are continuous flow along with pulse dose.

Indication-wise, the market categories are sleep apnea, asthma, chronic obstructive pulmonary disease, and more.

The key market end users analyzed in the report include hospitals and clinics, travel, homecare, and others.

Regional Study

Medical oxygen concentrators market’s regional segmentation covers Europe, the Americas, MEA or Middle East & Africa and Asia Pacific or APAC.

Since 2018, the Americas has remained the highest revenue generating market, backed by the extensive spread of a large number of renowned companies and the availability of developed home healthcare care services. The mounting prevalence of respiratory diseases and the supportive reimbursement policies, especially in Canada and the US also bolster the revenue generation in the region. A case in point, studies by the Centers for Disease Control and Prevention reveal that at present; close to 16 million Americans suffer from chronic obstructive pulmonary disease. Besides, government led initiatives like the approval granted by Federal Aviation Administration (FAA) for the use of portable oxygen concentrators in flights prompt further market expansion in the region.

Europe is touted to be the second highest gainer in subsequent years, with the market value being significantly bolstered by the massive geriatric populace and the escalating cases of COPD, pulmonary hypertension, fibrosis and asthma. Rising exposure to aerosols, chemicals, smoke, and various pollutants has boosted the chances of developing respiratory diseases in the region. EMA/European Medicines Agency says that there are currently over 30 million asthmatic patients in Europe, which improves the chances of the medical oxygen concentrators market garnering a higher position in the region.

APAC can demonstrate the fastest growth between 2019 and 2024, on account of the heightened preference for portable concentrators among travellers, rising healthcare spending and the augmenting awareness level about advanced equipment like oxygen concentrators. The health and living standards across the emerging countries is improving at a stellar speed, which has enhanced the general life expectancy of the people. This has been a key booster for the elderly population in the region, which is prone to a number of diseases and thereby, elevates the need for medical oxygen concentrators.

Key Players –

Medical oxygen concentrators key companies include Invacare Corporation, Inogen Inc., Charted Industries Inc., Koninklijke Philips N.V., Drive DeVilbiss Healthcare, Medtronic plc, GCE Group, Nidek Medical Products Inc., ResMed, and Teijin Limited, among others.

Related Reports –

amniotic membrane market

asia pacific aesthetics market

diabetic nephropathy market

chronic kidney disease market

For more information visit at MarketResearchFuture

[biotech-news-feed]

Source: National Heart, Lung, and Blood Institute - Related MedlinePlus Pages: Sickle Cell Disease #BioTech #science

[chic-chic2020]

มาฟัง 5 เหตุผลดีๆ ในการปลูกผักไว้ทานเอง

การปลูกผักใช้ความรักมากกว่าใช้เงิน ในช่วงเวลาที่ COVID-19 กำลังคุกคามเราทั้งสุขภาพและเงินในกระเป๋าเช่นนี้ อีกทั้งความจำเป็นต้องอยู่บ้านให้มากที่สุดทำให้เราเริ่มหันมาตระหนักถึงความมั่นคงทางอาหาร “เงินทองของมายา ข้าวปลาสิของจริง” ประโยควรรคทองนี้น่าจะสะท้อนภาวะช่วงนี้ได้ดีที่สุด

สังคมที่มีทางทางอาหารคือยามเมื่อ “ทุกคนในครอบครัวอาจเป็นอาหารอุดมด้วยโภชนาการอย่างใดอย่างหนึ่งเท่านั้นที่สามารถดำรงชีวิตที่มีสุขภาวะพอแข็งแรง” (World Food Summit, 1996) จมูกผักกินเอง เห็นว่าสามารถช่วยตัวเองได้ดีโดยที่ตัวเองทางอาหารบ้านใครปลูกผักก็ได้ค่อยๆดูรูปผักสวนผักสวยมาอวดกัน การปลูกผัก เคล็ดไม่ลับให้ผักสด สวยงามแต่ไร้��ารเคมี

1. อร่อย

ข้อดีข้อนี้เหตุผลที่ห้ามใจจริงไม่เลยที่ผักทุกต้นเป็นผลทุกลูกจะมีรสชาติลองปลูกผักสักต้นดูและรับประทานมารับประทานเมื่อถึงเวลาที่ลองกัดกินสดทุกอย่างดูจะสัมผัสถึงน้ำที่ ชุ่มฉ่ำจากเนื้อเยื้อของผักและรสชาติที่รสชาติไม่จืดชืดเป็นผลเนื่องมาจากสารอาหารที่ดีจากแสงแดดและจากความรู้สึกถึงของคุณ!

นอกจากนี้ด้วยเหตุผลที่การปลูกในรูปแบบอุตสาหกรรมนั้น บางครั้งจะมีการคัดเลือดสายพันธุ์ที่สามารถทนทานต่อโรคและแมลง มีอายุการวางบนซูเปอร์มาเก็ตที่ยาวนานกว่า หรืออาจจะเก็บเกี่ยวโดยที่ยังไม่สุกเต็มที่แล้วให้สุกระหว่างขนส่ง ดังนั้นหากเราเลือกเมล็ดพันธุ์อินทรีย์มาเพาะปลูก เราจึงได้รสชาติที่ดั้งเดิมของสายพันธุ์และมีรสที่สมบูรณ์ตามชนิดผักผลไม้มากกว่า ไม่เสียหายไปกับการเดินทางขนส่ง เพียงแค่คุณหยิบจากในกระถางที่บ้าน

2. ปลอดภัย ไม่มีสารเคมี และการปนเปื้อนของแบคทีเรีย

พืชผักที่เราปลูกเองเด็ดกินเองเราเองย่อมต้องปลูกโดยที่แน่ใจว่ากินได้ปลอดภัยแน่นอน เช่นนั้นแล้วสารเคมีไม่ใช่เรื่องต้องกังวล นอกจากนี้อีกภัยหนึ่งที่เรามองไม่เห็นเช่นเดียวกับสารเคมีคือการปนเปื้อนของแบคทีเรียดื้อยา ซึ่งอาจมีที่มาจากการใช้ปุ๋ยจากมูลสัตว์จากอุตสาหกรรมเนื้อสัตว์ที่ใช้ยาปฏิชีวนะเกินความจำเป็น และอาจปนเปื้อนไปสู่ผักที่เราซื้อกินได้ เคยมีเหตุการปนเปื้อนเชื้อซัลโมเนลลา (แบคทีเรียที่เป็นต้นเหตุของโรคอาหารเป็นพิษ)

3. อุดมด้วยสารอาหาร

ผักและผลไม้ คือแหล่งวิตามินและแร่ธาตุ ช่วยเสริมสร้างภูมิคุ้มกันให้กับร่างกายเรา แต่จากการสำรวจขององค์การอาหารและการเกษตรแห่งสหประชาชาติ (Food and Agriculture Organization of the United Nations) และองค์การอนามัยโลก (WHO) ระบุว่า อาหารการกินของคนเมืองนั้นอุดมไปด้วยไขมันและน้ำตาล ซึ่งส่งผลให้เกิดภาวะน้ำหนักเกิน ผักผลไม้ที่เราปลูกเองและสุกเก็บกินในช่วงระยะเวลาไม่นานนั้นจะมีแร่ธาตุและวิตามินครบถ้วนกว่าผักที่เราซื้อมา ระยะเวลาจากการขนส่งและการเก็บบ่มนั้นทำให้สารอาหารดี ๆ อาจลดลงได้ตามกาลเวลา ก็คือไม่เพียงแค่รสชาติการปลูกจากมือเราจะดีกว่าเท่านั้น ยังมีสารอาหารที่สูงกว่าด้วย

4. ผักแข็งแรง คุณก็แข็งแรง

แน่นอนว่ากว่าผักจะโตคุณจะไม่ได้เพียงแค่นั่ง ๆ นอน ๆ และได้ผักมา จะต้องมีการปรุงดิน หว่านเมล็ด รดน้ำ พรวนดิน ดูแลอยู่เสมอ กิจกรรมที่ต้องออกแรงและสัมผัสแสงแดดสายลมแบบนี้เหมาะยิ่งนักสำหรับช่วงที่เราต้องอยู่บ้านและขยับตัวน้อยลง แม้จะเป็นกระถางเล็ก ๆ ไม่ว่าอย่างไรก็ต้องออกแรงขยับแขนขา นิ้วมือ  มีงานวิจัยโดยสถาบันโรคหัวใจ ปอด และโลหิตวิทยาแห่งชาติ ประเทศสหรัฐอเมริกา (The National Heart, Lung, and Blood Institute :NHLBI) เผยว่า การทำสวนระยะเวลา 45 นาที เทียบเท่ากับการวิ่งระยะ 1.5 ไมล์ (2.4 กิโลเมตร) ในเวลา 15 นาที ผักแข็งแรงได้คุณก็แข็งแรงด้วย กินผักก็ยิ่งช่วยให้ร่างกายแข็งแรงอีก สุขภาพดีวนกันไป

5. มีกินได้เรื่อย ๆ

ย้อนกลับมาที่ทางนั้นมักจะกลับมาอีกครั้ง ปลูกผักกินเองนั่นคือเหตุผลที่อาหารที่เราสร้างได้แม้จะเพียงเล็กน้อยเพียงเล็กน้อยเท่านั้นที่มาของผักพริกผักบุ้ง คะน้าตำลึง ตำลึง... น้ำมันพืชจะยิ่งงอกงามช่วยประหยัดค่าอาหารได้เพียงเล็กน้อยเท่านั้น เมล็ดพืชที่ได้มาจากพืชที่สามารถปลูกได้สามารถปลูกต่อหรือแบ่งปันต่อได้เศษผักบางทีอาจจะเป็นกระเทียมหอมกระเทียมบีทรูทสปปะรด คอผักผักสลัด อาจปักลงดินและเติบโตต่อไปเรื่อย ๆ ไม่มีอะไรเหลือทิ้ง เศษอาหารก็กลับมาเป็นปุ๋ยใช้ต่อได้ตามความต้องการทางอาหารจากกระเช้าริมรั้วของเรา

ติดตามข่าวสารอัพเดตล่าสุดได้ที่: bromontfarm เรื่องราวเกษตรกร

[delicatemagazinedreamer]

Global Beating Heart Patch Market Is Estimated To Witness High Growth Owing To Rise in Cardiovascular Diseases

The global Beating Heart Patch Market is estimated to be valued at US$ 223.6 million in 2023 and is expected to exhibit a CAGR of 7.6% over the forecast period, as highlighted in a new report published by Coherent Market Insights.

Market Overview: Beating heart patches are a groundbreaking technology that has the potential to revolutionize the treatment of cardiovascular diseases. These patches are biocompatible materials that can be implanted onto damaged heart tissues, providing mechanical support and releasing growth factors to stimulate tissue regeneration. They offer several advantages such as improved heart function, reduced scar tissue formation, and potentially reducing the need for heart transplant surgeries.

Market Key Trends: One key trend in the beating heart patch market is the increasing prevalence of cardiovascular diseases worldwide. According to the World Health Organization (WHO), cardiovascular diseases remain the leading cause of death globally, accounting for over 17 million deaths annually. The rise in sedentary lifestyles, unhealthy diets, and aging populations contribute to the growing burden of cardiovascular diseases, creating a significant market opportunity for beating heart patches.

For example, in the United States alone, more than half a million people undergo heart surgeries each year. Beating heart patches offer a minimally invasive alternative to traditional surgical procedures, providing hope for patients who are not suitable candidates for open-heart surgeries.

PEST Analysis: Political: Governments worldwide are taking initiatives to improve cardiovascular healthcare infrastructure and promote research and development in regenerative medicine. For instance, the US government has invested significantly in regenerative medicine through organizations such as the National Institutes of Health (NIH) and the National Heart, Lung, and Blood Institute (NHLBI).

Economic: The increasing healthcare expenditure and rising disposable incomes in emerging economies are driving the demand for advanced cardiovascular treatments. Additionally, the cost-effectiveness of beating heart patches in the long run, as it reduces the need for repeated surgeries and hospitalizations, makes it an attractive solution for both patients and healthcare providers.

Social: The aging population and changing lifestyles, characterized by sedentary habits and poor dietary choices, contribute to the rising prevalence of cardiovascular diseases. The demand for innovative treatment options that can improve patient outcomes and quality of life is increasing. Beating heart patches offer a promising solution in this regard.

Technological: Advances in tissue engineering and regenerative medicine have paved the way for the development of beating heart patches. The use of biomaterials, stem cells, and growth factors in combination with 3D printing technology has enabled the creation of customized patches that can mimic the native heart tissue. These technological advancements drive the growth of the market.

Key Takeaways:

- Market size: The global Beating Heart Patch Market Demand is expected to witness high growth, exhibiting a CAGR of 7.6% over the forecast period. The growing prevalence of cardiovascular diseases is a significant driver for market growth.

- Regional analysis: North America is expected to be the fastest-growing and dominating region in the beating heart patch market. This can be attributed to the high prevalence of cardiovascular diseases, advanced healthcare infrastructure, and favorable government initiatives supporting regenerative medicine research.

- Key players: Key players operating in the global beating heart patch market include Harvard Apparatus Regenerative Technology, Inc., CorMatrix Cardiovascular, Inc., Acell Inc., Cytograft Tissue Engineering, Inc., Biomatrica, Inc., Tepha, Inc., LifeNet Health, Inc., CollPlant Ltd., SynCardia Systems, LLC, Cardiovascular Systems, Inc., Biotronik SE & Co. KG, Admedus Ltd., C. R. Bard, Inc., W. L. Gore & Associates, Inc., and Xenogenics Corporation. These players are actively involved in research and development activities to enhance their product offerings and gain a competitive edge in the market.

In conclusion, the global beating heart patch market shows immense potential for growth due to the increasing prevalence of cardiovascular diseases. These patches offer a minimally invasive and effective treatment option, providing hope for patients and reducing the burden on the healthcare system. The advancements in regenerative medicine and technology continue to drive innovation in this field.

[getthebutters]

Thriving with Sickle Cell Disease: A Guide to Living Well

Living with sickle cell disease can be a challenge, but with the right support and care, it is possible to manage the condition effectively and live a healthy and fulfilling life. Here are some steps you can take to live well with sickle cell disease:

1.       Work with a healthcare team: It is important to have a healthcare team that includes a hematologist, primary care physician, and other specialists, as needed. Your healthcare team can help you manage your symptoms and provide the necessary treatment to prevent complications.

2.       Take your meds: Just because you’re prescribed doesn’t mean you actually take them. Take your meds!

3.       Manage pain: Sickle cell disease can cause severe pain and discomfort. Work with your healthcare team to develop a pain management plan, which may include over-the-counter pain relievers, prescription medications, and complementary therapies like massage or acupuncture.

4.       Stay hydrated: Dehydration can trigger sickle cell crisis, so it is important to drink plenty of water, especially during hot weather or when you are physically active.

5.       Maintain a healthy diet: A balanced diet that includes plenty of fruits, vegetables, lean proteins, and whole grains can help you maintain good health and manage your symptoms.

6.       Exercise regularly: Regular exercise can help improve your physical fitness, boost your energy levels, and manage pain. However, it is important to talk to your healthcare team before starting any new exercise program.

7.       Get adequate sleep: Good sleep is important for overall health and can help you manage pain and stress.

8.       Manage stress: Stress can trigger sickle cell crisis, so it is important to find healthy ways to manage stress, such as through relaxation techniques, therapy, or support groups.

9.       Mental health: Sickle cell is stressful and often occurs with anxiety and depression. It’s important to be patient and forgiving with yourself and your varying limitations. Therapy & medications can be helpful. Your medical team will be able to help you.

10.   Lose the shame: Don’t avoid soothing your discomforts to please others. If you need to rock, rub, hum, or go fetal to cope with the pain, do it. You’re living with a chronic illness that doesn’t give a fuck about decorum and politeness.

11.   Be prepared: Get your go bag ready for the possibility of hospitalization. Keep it with you if you’re staying over some place. A separate smaller bag for day-to-day carry is recommended as well.

12.   Avoid triggers: Certain factors, such as high altitude, cold weather, and dehydration, can trigger sickle cell crisis. Talk to your healthcare team about your triggers and how to avoid them.

13.   Stay up-to-date with vaccinations: Regular vaccinations can help protect you from infections, which can be dangerous for people with sickle cell disease.

14.   Connect with a support network: Connecting with other people with sickle cell disease or a support group can provide emotional support and help you manage your condition more effectively.

Social media accounts to follow:

@moonlitdna Instagram, Tiktok, Twitter, Reddit, Twitch

@TheHemenp Instagram & Tiktok, www.TheHemenp.com

@drzsicklecell Instagram

@letstalksickle Instagram

@sicklecell101 Instagram

@sicklecelluk Instagram

 Orgs to follow:

Sickle Cell Disease Association of America (SCDAA): This is a national organization that provides support, education, and advocacy for people with sickle cell disease.

National Heart, Lung, and Blood Institute (NHLBI): This is a federal institute that provides information and resources on sickle cell disease, including research updates and clinical trials.

Sickle Cell Disease Research and Education Society (SCDRES): This is a non-profit organization that provides support, education, and advocacy for people with sickle cell disease.