#Microbiology & Biotechnology

[0ctogus]

CRISPR was already on thin fucking ice as a serious name for a biotech technique and now they made up CRISPY-BRED are you joking

[mindblowingscience]

Leiden Ph.D. candidate Jo-Anne Verschoor discovered that nearly 20% of the bacterial strains she studied could degrade plastic, though they needed some encouragement to do so. "Bacteria are just like people," says Verschoor. Her research was published in the journal Communications Biology. Some of the world's smallest organisms could play a significant role in solving the problem of plastic pollution. Increasingly, it is being discovered how certain bacteria can break down plastic into small particles, which can then be recycled. Moreover, Verschoor's research reveals that many more bacteria than previously thought can degrade certain types of plastics. The 27-year-old Leiden microbiologist was able to use a large collection of Streptomyces bacteria, which were already available at the university as scientists use them in the search for new antibiotics.

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[o2studies]

Calling all science students and enthusiasts!!

I would absolutely love to have a science-revolving passion project and I’ve narrowed it down to a blog/blog-type-website. I love learning about science but so rarely take the time to actually research the things that interest me. With being a high school student, exams and life this is quite a big task to handle for 1 person and I’d love others to contribute to this!

This is by no means a set plan yet, I’m just sharing a rough idea, so if you could please interact with this post or dm me if you would be interested in something of this kind. Even if you see this 5 months after this was posted (and hopefully a working project or at least WIP) still reach out if you’re interested.

You don’t have to be a great writer for this either nor fascinated about each and every science. My favourite is chemistry, but it would be nice if this project could incorporate the 3 main branches of science: biology, chemistry and physics. It depends on if people would be interested in reading something like this or participating in, and their preferred subjects. You could write about astronomy as a whole, or go into chemistry and analysing electronic configuration, talking about your favourite dinosaur bones in palaeontology, a passive behaviour analysis in psychology, or explaining how exactly scabs work in biology. These would probably be short to mid-length entries and 1/2 times a month.

But this is just my idea and how far I’ve gone with it, feedback is appreciated, there will be more updates to come (not too many until afer my exams in May tho), and I appreciate any reblogs to share this idea with others!

Hopefully a couple people would like to help out in this project and please ask questions if you have any (as a dm or ask) ^^

[ishaeji]

Electric Bacteria: Harnessing Nature's Microscopic Power Plants for a Sustainable Future

Electric bacteria, or electrogenic microbes, are fascinating organisms capable of generating electricity as part of their natural metabolic processes. Found in diverse environments such as soil, freshwater, and even the human gut, these bacteria can convert organic compounds into electrical energy. This unique ability is primarily observed in species like Shewanella and Geobacter, which use conductive proteins to transfer electrons to external electrodes, functioning like microscopic power plants.

Shewanella oneidensis and Geobacter sulfurreducens are notable examples. These bacteria can form biofilms on electrodes, creating a microbial fuel cell that generates electricity. This phenomenon is not just a scientific curiosity but has practical applications. For instance, microbial fuel cells can be used in wastewater treatment plants to both clean water and generate electricity simultaneously. Additionally, electrogenic bacteria are being explored for bioremediation, helping to clean up polluted environments by breaking down contaminants and converting them into less harmful substances.

The potential of electric bacteria extends to sustainable energy solutions. By harnessing their natural abilities, researchers aim to develop innovative technologies that offer renewable energy sources. The intersection of microbiology and energy technology could lead to breakthroughs that address some of the world's pressing environmental challenges.

References:

Lovley, D. R. (2012). Electromicrobiology. Annual Review of Microbiology, 66, 391-409.

Nealson, K. H., & Rowe, A. R. (2016). Electromicrobiology: Realities, grand challenges, goals and predictions. Microbial Biotechnology, 9(5), 595-600.

Logan, B. E. (2009). Exoelectrogenic bacteria that power microbial fuel cells. Nature Reviews Microbiology, 7(5), 375-381.

[biotechstudentlife]

Carbohydrates MCQ 25 Link in bio ☝️ for more mcqs recommendations #biotechnology #biology #science #microbiology #biotech #biochemistry #molecularbiology #research #genetics #scientist #dna #medicine #laboratory #biotechnologist #cellbiology #lab #microbiologist #medical #chemistry #biotechnologystudent #biologystudent #bio #biologymemes #lifescience #neet #bioinformatics #covid #zoology #microscope #bacteria (at Royal City Nanded) https://www.instagram.com/p/Cp4AbWivdeN/?igshid=NGJjMDIxMWI=

[wisdomfish]

Anyone who has looked at the health statistics, medical conditions, and sexually transmitted diseases that characterize the gay male lifestyle will know that such willful destruction of the human body is neither loving nor liberating. 

~ Carl Trueman

[sdsbiology]

It's my life 🙂🧑‍🔬 .. Follow & explore the amazing science world🔬👇 @sdsbiology for exploring the amazing world of biology and science 😍😍❤️#sdsbiology ♡ ㅤ    ❍ㅤ     ⎙ㅤ     ⌲ ˡᶦᵏᵉ ᶜᵒᵐᵐᵉⁿᵗ ˢᵃᵛᵉ ˢʰᵃʳᵉ 🅻🅸🅺🅴 , 🆂🅷🅰🆁🅴 🅰🅽🅳 🅲🅾🅼🅼🅴🅽🆃 .. #medical #biology #cellbiology #college #immunology #genetics #ecology #virus #bacteria #science #microbiology #biotechnology #biotech #zoology #neet #bacteriology #bacteriologia  #hormones #viruses #virology #school #mbbs #instagram #ınstagood #neet #cbse #aiims #glucose #neet . https://www.instagram.com/p/CpnSbl4J1Dh/?igshid=NGJjMDIxMWI=

[vindhyavasiniacademy]

[traaansfem]

@butterfly-sapphire @witchestower @catboybiologist (please tag some people who know gastroenterology sierra that is NOT my zone of expertise)

Alright, so I found some actual papers on this, and my current suspicion about the function of the appendix is linked to this (assuming a bacterial strain not associated with pathogenicity suddenly becoming malevolent and colonizing areas generally held by other gut flora and causing sickness is a common occurrence in times of famine historically.). ANYWAY. The appendix is known to serve as a reservoir of gut flora, but it has weird stuff going on that didn't fit other models of predicted functions- so I suspect that a good hypothesis to test if these viroid adjacent loose "RNA obelisk" plasmid lookin fuckers would be as follows.

Test for presence of obelisk RNA in mouth/saliva samples, check stool samples, and check other tissues if there are volunteers and people willing to have things stuck up their butt or down their throat for science. Determine if there is a correlation between their presence or absence and gut health (I would assume you want a little- enough to trigger some immune response and keep goblet cells.. well, not sharp per se. But alert.). Lots of confounding variables to control for here, you'd need a broad data set.

Secondarily, if there is some negative health outcome, check against appendicitis and appendectomy tissue samples- that is to say, cross reference appendix samples for the presence of obelisks.

This would serve a preliminary purpose of figuring out if another, more ethically dubious test would be necessary at all.

Because I suspect that these obelisks can be corruptive to the proper function of an individual body's gut microbiome, like virions can be to plant vasculature and development. So if they interfere with the health of a gut microbiome, then it stands to reason that an appendix, which serves as a natural reserve for healthy digestive bacteria would have SOME way to keep them out. My suspicion is that the environment of a healthy appendix is designed to be hostile, even inimical to these obelisks. Thus, I would suspect that RNA detecting macrophages and phagocytic cells would be busying themselves in the appendix, cleaving and destroying invading obelisks to maintain a healthy reserve of gut bacteria. Or perhaps an elevated presence of an extracellular RNA destroying enzyme.

So, assuming that the appendix has some cellular or humoral guard dog mechanism, then loss of function in some phagocytic immune cells, loss of function or lack of function in whichever extracellular RNA cleavage and disintegration enzyme you care to name, temporary or permanent immune system collapse, autoimmune disorders, food poisoning (acute OR chronic), starvation, famine conditions, long term nutrient depletion or deficiencies, mutations in the genes coding for the enzymes that up or downregulate them in ways that result in a depletion of them as the body clears them or overproduces them... All of those could contribute to sudden bacterial or viral infections of the appendix, and particularly if the bacteria was already present and considered trustworthy and non hazardous by pathogen identification pathways. And the swelling and subsequent degeneration of the appendix itself could take days, weeks or even months to be apparent after whatever illness(es) or health issue(s) actually caused the antecedent issue.

The main issue I have with this is that you can establish correlation pretty easily here, but establishing causation would almost certainly necessitate invasive tests, removal of a healthy individual's appendix and immediate study thereof, testing the proteins and enzymes present, and genetic testing to determine if some pathways associated with those enzymes are not present in people who have needed appendectomies.

While you could make an argument that this could be done with organ donors who had given consent to have their bodies used for science, the loss of those organs for harvesting and subsequent transplant would result in disruption of the pathways for the appendix, which would skew data immensely. And an issue with the inverse of that, where you purposefully attempt to disrupt the function of the suspected mechanisms used for keeping the appendix healthy by disrupting the pathways for removal of those suspected causative agents for pathogenicity (RNA obelisks), is that if you get the data you needed, you just gave a coms patient appendicitis and may have ruined their other organs for transplant into other people. Whoopsie.

Anyway, there's a whole medical ethics conundrum and a bioethical tarpit to try to avoid here, so I think it might be best to wait until other people specifically studying the human gut weigh in on safer methodologies.

And that's not even touching on the likelihood of preliminary tests with other animals known to have structures that are both homologous AND analogous to the human appendix (start as low on the phylogenetic tree as you can is the usual rule), before working up to mammals and MAYBE lower primates before even getting CLOSE to humans.

Anyway, that's my 10:50PM to 11:29PM rambles. I'll schedule this one for later tomorrow, and I'll pester some microbiologists and immunologists I know about this.

Of course, this assumes the preprint isn't full of shit, and almost all of the papers promising a dramatic upheaval in biology are. The only reason I'm holding out any hope here is that RNA detection got overhauled a lot for covid detection and subsequent attempts at mitigation via biotechnology, so it MIGHT be possible that we missed this. So far. The specifics are dubious though. I hope they pan out though, this could be monumental! Monolithic, even! Why, you might as well carve it into an obelisk :3

They just discovered a new kind of organism that isn't a virus or bacterium

[marketingreportz]

Real-time PCR Market - Forecast(2024 - 2030)

𝐑𝐞𝐚𝐥-𝐓𝐢𝐦𝐞 𝐏𝐂𝐑: 𝐄𝐬𝐬𝐞𝐧𝐭𝐢𝐚𝐥 𝐓𝐨𝐨𝐥 𝐟𝐨𝐫 𝐌𝐨𝐝𝐞𝐫𝐧 𝐌𝐨𝐥𝐞𝐜𝐮𝐥𝐚𝐫 𝐁𝐢𝐨𝐥𝐨𝐠𝐲 𝐄𝐱𝐩𝐥𝐚𝐢𝐧𝐞𝐝

The global real-time PCR (qPCR) market is experiencing significant growth, driven by several key factors. The market, valued at $22.03 billion in 2024, is projected to reach $27.78 billion by 2028. This growth is largely due to the increasing prevalence of infectious diseases, the rise of cancer diagnostics, and expanding research in genomics.

The method that creates multiple copies of a particular DNA region in vitro uses the polymerase chain reaction. The technique relies on a DNA polymerase known as TAQ polymerase, which is thermostable. Thermus aquaticus is used to produce this polymerase. They occupy hot springs and hydrothermal vents. The target region to be reproduced is produced in large numbers by the PCR reaction, which involves repeat cycles at a range of temperatures.

Real-time PCR systems are laboratory instruments used to increase the number of copies of specific DNA segments. The rising prevalence of chronic and infectious diseases is driving the growth of the market for real-time polymerase chain reaction (PCR). Furthermore, forensics, diagnostics, and proteomics research advancements are creating potential growth opportunities for the real-time polymerase chain reaction (PCR) market.

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The polymerase chain reaction (PCR) has been used and shown to be effective in detecting minute amounts of a wide range of infectious diseases. The best conditions for amplification vary depending on the organisms of interest. PCR was used as a rapid and sensitive method for detecting infectious agents, and three assay systems were developed, one for the amplification of human T cell leukaemia virus type I, one for Mycobacterium tuberculosis, and one for Mycoplasma pneumoniae. These all factors will propel the market.

The increased use of the polymerase chain reaction for cancer diagnosis is expected to drive market growth in the coming years. All of these factors are responsible for creating a greater demand for this technique in the coming years, research and development activities for providing innovative molecular biology and forensic science as there has been a great demand for genetic engineering as well as personalized medicines.

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The global real-time PCR (qPCR) market is experiencing significant growth, driven by several key factors. The market, valued at $22.03 billion in 2024, is projected to reach $27.78 billion by 2028. This growth is largely due to the increasing prevalence of infectious diseases, the rise of cancer diagnostics, and expanding research in genomics. Real-time PCR remains a vital tool in healthcare, pharmaceuticals, and biotechnology for applications such as early disease detection, personalized medicine, and molecular diagnostics​

COVID-19 had a substantial impact on the PCR market, as demand for reliable diagnostic tools surged. The pandemic underscored the importance of real-time PCR for detecting viral infections like SARS-CoV-2, making it an essential part of disease management worldwide. This trend continues to fuel demand, especially as the technology evolves with innovations like digital PCR and multiplex assays

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Regionally, North America dominates the market due to its strong healthcare infrastructure and high prevalence of diseases like hepatitis and HIV. However, the Asia-Pacific region is expected to see the fastest growth, with rising patient awareness and investments in healthcare across countries like China, Japan, 

More about Real-time PCR Market report click here 

[mindblowingscience]

A new study titled "Biomimetic hepatic lobules from three-dimensional imprinted cell sheets" has been led by Prof. Yuanjin Zhao of the Department of Hepatobiliary Surgery, Hepatobiliary Institute, Nanjing Drum Tower Hospital, Medical School, of Nanjing University in China. The research is published in the journal Science Bulletin. To establish high-precision liver lobules, researchers utilized spatial proteogenomic datasets to identify the multicellular specific composition in the normal human liver. Based on this data and cell membrane slicing technology, researchers then employed a newly developed 3D printing strategy to print and carve liver cell sheets with hexagonal hollow cross-sectional structures.

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[mere-device]

can anyone tell me what species these contaminants are? i really fucked up these plates :')

[yashmedica]

Lab Equipment Market Growth: From Biochemistry (Agilent) to Genetics (Thermo Fisher) & Beyond!

Latest trends in the laboratory equipment market with a focus on application insights such as biochemistry, genetic testing, microbiology, and endocrinology | Growth drivers, innovations from top players like Thermo Fisher Scientific and Roche Diagnostics

Laboratory Equipment Market: Application Insights – Biochemistry, Genetic Testing & Beyond! The Laboratory Equipment Market is booming, fueled by advancements across various scientific disciplines. As an investor, navigating this diverse landscape requires understanding the key application segments driving growth. This article analyzes the most commonly asked questions regarding application…

[ishaeji]

Silent Invaders: The Alarming Impact of Microplastics on Plant Health and Ecosystems

Microplastics, tiny plastic particles less than 5mm in size, have emerged as a significant environmental threat. While their impact on marine life is well-documented, recent studies reveal a disturbing trend: microplastics are infiltrating terrestrial ecosystems and affecting plant life.

Microplastics enter the soil through various means, including sewage sludge, plastic mulching, and atmospheric deposition. Once in the soil, these particles can hinder plant growth and development. Research indicates that microplastics alter soil structure, affecting its water retention and aeration properties, which are crucial for plant health. Moreover, microplastics can adsorb toxic pollutants, introducing them into the soil environment, which can be detrimental to plants (Rillig et al., 2019).

Alarmingly, microplastics have been shown to stunt root growth, impair seed germination, and reduce overall plant biomass. These effects not only compromise plant health but also threaten the entire ecosystem, as plants are foundational to terrestrial food webs (de Souza Machado et al., 2018). Furthermore, the presence of microplastics in agricultural soils can reduce crop yields, posing a threat to food security (Boots et al., 2019).

The infiltration of microplastics into soil and their adverse effects on plants highlight an urgent need for comprehensive policies and practices to mitigate plastic pollution. Failure to address this issue could lead to cascading ecological and agricultural crises. Source:

Rillig, M. C., et al. (2019). "Microplastic effects on plants." Nature Reviews Earth & Environment, 1(2), 1-4.

de Souza Machado, A. A., et al. (2018). "Impacts of microplastics on the soil biophysical environment." Environmental Science & Technology, 52(16), 9656-9665.

Boots, B., et al. (2019). "Impact of microplastics in agriculture and land management." Environmental Science & Technology, 53(4), 1906-1915.

[biotechstudentlife]

Protein MCQ 46 Link in bio ☝️ for more mcqs recommendations #biotechnology #biology #science #microbiology #biotech #biochemistry #molecularbiology #research #genetics #scientist #dna #medicine #laboratory #biotechnologist #cellbiology #lab #microbiologist #medical #chemistry #biotechnologystudent #biologystudent #bio #biologymemes #lifescience #neet #bioinformatics #covid #zoology #microscope #bacteria (at Royal City Nanded) https://www.instagram.com/p/Cp9r2uFPedi/?igshid=NGJjMDIxMWI=

[academic1995]

Biology and Life Sciences| #academicexcellenceawards #sciencefather#awa...