#Metal Chelates Market Research

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Metal Chelates Market - Forecast (2023 - 2028)

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The Origins, Nutritional Content, and Health Benefits of Probiotic Tea

Origin and Nutritional Content of Probiotic tea Probiotic tea is a fermented, slightly alcoholic and effervescent sweetened black or green tea drink prepared using Probiotic tea culture, bacteria and yeast. Probiotic tea is said to have originated in Northeast China or Russia around 220 BC. The Probiotic tea culture is made up of a symbiotic colony of bacteria and yeast (SCOBY) that feeds on sugar and antioxidants in the tea to carry out fermentation. This process yields a range of nutrients as well as beneficial acids, enzymes and probiotics. Some key nutrients provided by Probiotic tea include B vitamins, amino acids, polyphenols, organic acids and glucose. The fermentation also produces small amounts of alcohol and carbonation. Potential Health Benefits of Probiotics in Kombucha During fermentation, the culture produces a range of probiotic bacteria and yeast associated with numerous health benefits. Chief among these are Lactobacillus and Acetobacter which have been shown to support digestive health, boost immunity and promote natural detoxification in the liver. Research links the probiotics in Probiotic tea to improved gut motility, reduced symptoms of irritable bowel syndrome and protection against harmful microbes overgrowth. They may also help those on antibiotic treatments by replenishing depleted gut bacteria post-antibiotic use. Including Probiotic tea as part of a daily diet could help ensure adequate probiotic intake for optimum digestive and immune health. Detoxification and Liver Support Properties The organic acids produced during Kombucha fermentation include acetic acid, lactic acid and glucuronic acid which is a major component of phase II liver detoxification. Glucuronic acid plays a key role in conjugating and eliminating both endogenous and exogenous toxins from the body. This makes Probiotic tea a useful support for natural detox due to its glucuronic acid content. Along with glucuronic acid, antioxidants like polyphenols also assist the liver in combating free radical damage caused by toxins. Some research indicates Probiotic tea may aid in removing heavy metals from the body through chelation, benefit liver function and prevent toxin accumulation. May Help Manage Blood Sugar Levels The acetic acid found in Probiotic tea is a main component of apple cider vinegar which has traditionally been used to help manage blood sugar levels. Probiotic tea contains glutamic acid which may help regulate insulin sensitivity. Preliminary studies on animals suggest Probiotic tea possesses anti-hyperglycemic effects and could assist in maintaining healthy blood sugar control, making it a suitable option for diabetic individuals. However, human trials are still needed to confirm Probiotic tea's anti-diabetic properties. Drinking Probiotic tea in moderation as part of an overall healthy diet is recommended for possible blood sugar support. Antioxidant Content and Anti-aging Effects Kombucha boasts a profile of antioxidant compounds that protect cells from free radical damage. This includes antioxidants like polyphenols, flavonoids and other phytonutrients carried over from green or black tea into the Probiotic tea. Antioxidants combat oxidative stress implicated in accelerated aging and disease. Research has found Probiotic tea effective at scavenging reactive oxygen species and may reduce toxicity associated with diabetes, heavy metals and pesticides due to its antioxidant activity. Drinking Probiotic tea regularly could help delay signs of aging by supporting optimal cellular health through its antioxidant nutrients.

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Alice Mutum is a seasoned senior content editor at Coherent Market Insights, leveraging extensive expertise gained from her previous role as a content writer. With seven years in content development, Alice masterfully employs SEO best practices and cutting-edge digital marketing strategies to craft high-ranking, impactful content. As an editor, she meticulously ensures flawless grammar and punctuation, precise data accuracy, and perfect alignment with audience needs in every research report. Alice's dedication to excellence and her strategic approach to content make her an invaluable asset in the world of market insights.

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Ion Exchange Resins Market Size to Surpass USD 2.1 Billion by 2031

The global ion exchange resin market was estimated to have acquired US$ 1.4 billion in 2022. It is anticipated to register a 4.6% CAGR from 2023 to 2031 and by 2031, the market is likely to gain US$ 2.1 billion.

Ion exchange resins are used in waste treatment processes for the removal of heavy metals and other contaminants. The emphasis on waste recovery and recycling presents opportunities for the ion exchange resin market.

The development of customized and specialty ion exchange resins tailored to specific industrial processes and applications provides a niche market opportunity.

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Key Findings of Market Report

On the basis of product, the chelating resins segment is anticipated to lead the ion exchange resin market, owing to high demand in water treatment processes for the removal of heavy metals and trace elements.

In terms of application, the sugar refining segment is expected to dominate the market growth, attributed to increased demand for ion exchange resins in the sugar industry for the purification and decolorization of sugar solutions.

By end user, the pharmaceutical segment is expected to accelerate the demand for ion exchange resin, owing to growing demand for ion exchange resins in pharmaceutical manufacturing for drug purification and water treatment.

Trends for Ion Exchange Resin Market 

The increasing demand for clean water for industrial and domestic purposes is driving the use of ion exchange resins in water treatment applications. The resins are effective in removing impurities and contaminants from water.

Rapid industrialization in emerging economies is leading to increased water pollution, necessitating the use of ion exchange resins for water purification in various industries such as power generation, chemicals, and pharmaceuticals.

Ion exchange resins are widely used in the food and beverage industry for processes such as sugar refining, sweetener production, and the treatment of beverages. The growth of this industry is contributing to the demand for ion exchange resins.

Ongoing research and development activities are leading to the development of improved ion exchange resin technologies, enhancing their efficiency and expanding their application areas.

Global Market for Ion Exchange Resin: Regional Outlook 

Various reasons are propelling the growth of the ion exchange resin market in different regions. The regions include,

North America

The increasing need for efficient water and wastewater treatment solutions, driven by population growth, urbanization, and environmental concerns, is expected to stimulate the demand for ion exchange resins.

The diverse industrial base in North America, including the chemicals, pharmaceuticals, power generation, and electronics industries, creates a significant demand for ion exchange resins in various applications, such as process water treatment and purification.

Ongoing investments in upgrading and expanding water infrastructure, including treatment plants and distribution systems, is expected to accelerate the demand for ion exchange resins in North America.

Asia Pacific

The growth of the chemical and petrochemical industries in the region, particularly in countries like China, is expected to increase the demand for ion exchange resins for applications such as chemical processing and purification.

The expanding pharmaceutical and biotechnology sectors in Asia Pacific are anticipated to create sustained demand for ion exchange resins, particularly in applications related to drug manufacturing and purification processes.

Global Ion Exchange Resin Market: Key Players  

The following companies are well known participants in the global ion exchange resin market: 

Ionic Systems Ltd.

ResinTech, Inc.

Thermax Limited

Ion Exchange (India) Limited

Evoqua Water Technologies LLC

Eichrom Technologies, LLC

The Dow Chemical Company

Purolite

Lanxess AG

Mitsubishi Chemical Corporation

Novasep

Finex Oy

Global Ion Exchange Resin Market Segmentation  

Product

Adsorbent Resins

Chelating Resins

Strong Acid Cation Resins

Weak Acid Cation Resins

Strong Base Anion Resins

Weak Base Anion Resins

Mixed Bed Resins

Application

Sugar Refining

Liquid Glucose

Uranium Mining

Gold Mining

MTBE Catalysis

TAME

Bisphenol A

Industrial Water Treatment

Food & Beverages

Ultrapure Water

Pharmaceutical

Municipal Water Treatment

Water Softening

Others (Other Mining, Other Chemicals, etc.)

End User

Pharmaceutical

Industrial Water Treatment

Municipal Water Treatment

Mining

Electrical & Electronics

Power Generation

Nuclear Power

Food & Beverages

Chemical Production

Others (R&D, etc.)

Region

North America

Latin America

Europe

Asia Pacific

Middle East & Africa

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Chitosan Market Is Experiencing Significant Growth

The chitosan market is witnessing significant growth, and it will continue this trend in the coming years.

This is ascribed to the increasing acceptance of chitosan in food and beverage, wastewater purification, pharmaceutical, cosmetic, and agrochemical, bioplastic applications.

The pandemic of COVID-19 had a positive impact on this industry because numerous researchers have acknowledged chitosan as a possible agent for the drug delivery systems of COVID-19. This can be because of its construction that comprises free hydroxy & amine groups, which can simply link with other molecules via a hydrogen bond.

In the stringent lockdowns and various other rules, governments have allowed the healthcare sector to function, to deliver COVID-19 treatment, which has assisted the industry expansion.

Food preservatives are employed to enhance the lifespan of perishable food products. The conventional approaches to food preservation comprise the use of formalin, which has been substituted by chitosan significantly because of the poisonous effects of formalin on people.

The shrimp category, based on source, was the largest contributor to the chitosan market in recent years. Moreover, this category will further advance at a significant compound annual growth rate in the years to come.

This is mainly because of the high chitin content in shrimp shells, coupled with the increasing need for shrimp chitosan to treat wastewater and as a component in food preservatives.

In the past few years, the water treatment category, on the basis of application, led the industry. Moreover, this category is also likely to advance significantly in the years to come.

This is primarily because of the coagulation capability of chitosan on both the inorganic and organic substances present in water. In addition, it also assists in eliminating dyes as well as in flocculation, in water treatment.

The industrial category, based on grade, led the industry in the past few years. This is mainly because of the increasing rate of industrialization across the globe, which is boosting the utilization of industrial-grade chitosan in medical & pharmaceuticals, water treatment, and cosmetics applications.

APAC was the largest contributor to the industry in the past few years. Furthermore, the region is likely to advance at the fastest compound annual growth rate in the years to come. This is primarily because of the chelating assets of chitosan, which makes it suitable for the treatment of heavy-metal-laden industrial wastes.

Additionally, the high funding being made by the government as well as private administrations for water treatment in Malaysia, India, and China will further boost the expansion of this industry.

With its increasing utilization in the biomedical sector and wastewater treatment, the chitosan industry will continuously advance in the coming years.

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Exploring the Biomedical Applications of Itaconic Acid in Drug Delivery and Biomaterials

Itaconic Acid: A versatile platform chemical gaining significance Production and Applications of Methylenesuccinic Acid Itaconic acid is produced through fermentation of carbohydrates like glucose, sucrose or molasses by fungi species Aspergillus itaconicus or Ustilago maydis. The process involves fungi growth in aqueous medium containing nutrients and sugars followed by acidification to extract methylenesuccinic acid. The medium is then filtered and purified using ion-exchange or crystallization to achieve high purity methylenesuccinic acid. Some key players involved in commercial production of methylenesuccinic acid include Itaconix Corporation, Qingdao Kehai Biochemistry Co., Ltd. and Zhejiang Guoguang Biochemistry Co., Ltd. Current global production capacity of methylenesuccinic acid stands at over 50,000 tons per year. Uses in Polymers and Specialty Chemicals Manufacturing Being a dicarboxylic acid, methylenesuccinic acid serves as an important building block chemical for polymers and specialty chemicals. It finds significant usage in manufacturing of synthetic latex, superabsorbent polymers, chelating agents and copolymers for diverse applications. As a comonomer for acrylate or methacrylate polymers, methylenesuccinic acid improves water-absorbency and acid-base properties. Its copolymers with acrylates and styrene are used in paper coatings, adhesives, thickeners and dispersants. Methylenesuccinic acid also acts as a complexing agent for heavy metal ions and is used in industrial and agricultural chelating formulations. Potential in Novel Therapeutic Applications Novel applications of itaconic acid are being researched in the medical field as well. Some studies have revealed its anti-fungal, antibacterial and anti-viral properties. Research is in progress to develop itaconate derivatives with enhanced bioactivity against multi-drug resistant pathogens. Methylenesuccinic acid is also known regulate inflammatory responses in human body by inhibiting certain enzymes. This makes it a potential candidate for developing novel anti-inflammatory pharmaceuticals. Exploratory trials indicate it may assist in managing conditions like diabetes, neurodegeneration and cancer. Though in early stages, these therapeutic applications open up completely new frontiers for methylenesuccinic acid if successfully commercialized in future. To conclude, with its unique structural attributes and bio-based origin, methylenesuccinic acid has emerged as a very important specialty platform chemical with broad scope across industries. Backed by steady growth in end-use markets and rising sustainability emphasis, the methylenesuccinic acid industry is rightly positioned for significant expansion globally in the coming years. Ongoing R&D and commercial initiatives also point towards novel product concepts and applications further accentuating the industrial relevance of this multifaceted organic acid.

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Agricultural Chelates Market Gaining Momentum Ahead on Innovation

Advance Market Analytics published a new research publication on "Agricultural Chelates Market Insights, to 2028" with 232 pages and enriched with self-explained Tables and charts in presentable format. In the Study you will find new evolving Trends, Drivers, Restraints, Opportunities generated by targeting market associated stakeholders. The growth of the Agricultural Chelates market was mainly driven by the increasing R&D spending across the world.

Get Free Exclusive PDF Sample Copy of This Research @ https://www.advancemarketanalytics.com/sample-report/61371-global-agricultural-chelates-market The Agricultural Chelates Market report covers extensive analysis of the key market players, along with their business overview, expansion plans, and strategies. The key players studied in the report include: BASF SE (Germany), Haifa Chemicals (Israel), Syngenta AG (Switzerland), AkzoNobel N.V. (Netherlands), Nufarm Ltd. (Australia), Deretil Agronutritional (Spain), Shandong IRO Cheating Chemicals Co. Ltd. (China), Protex International (France), Van Iperen International (The Netherlands), The Andersons Plant Nutrient Group (United States). Definition: Agriculture Chelates is a micronutrient requirement of plants, which is supplied by complexes containing chelated metals. Theses Chelates used in a wide variety of crops such as corn, bush beans, cucumbers, and citrus groves. The critical factors for the use of any of these chelates are the stability constant and the cost to prepare a pound of chelated metal such as iron or zinc. Chelated compounds are more stable than non-chelated compounds. Therefore, metallic chelates are widely used in agriculture as micronutrient fertilizers to supply plants with Iron, Manganese, Zinc, and Copper.

The following fragment talks about the Agricultural Chelates market types, applications, End-Users, Deployment model etc. A thorough analysis of Agricultural Chelates Market Segmentation: by Type (EDTA, EDDHA, DTPA, IDHA), Application (Soil, Seed Dressing, Foliar Sprays, Hydroponics), Core Type (Cereals and Grains, Oilseeds and Pulses, Fruits and Vegetables) Agricultural Chelates Market Drivers:

Chelated-Iron Agricultural Micronutrients Is Majorly Driven By the Challenges Faced In Agricultural Activities

Poor Soil Quality Is Observed To Be the Foremost Factor Fuelling Demand for Chelated-Iron as Agricultural Micronutrient

Agricultural Chelates Market Trends:

Increasing Incidences of Micronutrient Deficiency

Increasing Agricultural Chelates Consumption in the Asia - Pacific Region Due To Increasing Population

Agricultural Chelates Market Growth Opportunities:

Strong Growth Opportunity Due To Growing Food Consumption

As the Agricultural Chelates market is becoming increasingly competitive, it has become imperative for businesses to keep a constant watch on their competitor strategies and other changing trends in the Agricultural Chelates market. Scope of Agricultural Chelates market intelligence has proliferated to include comprehensive analysis and analytics that can help revamp business models and projections to suit current business requirements. We help our customers settle on more intelligent choices to accomplish quick business development. Our strength lies in the unbeaten diversity of our global market research teams, innovative research methodologies, and unique perspective that merge seamlessly to offer customized solutions for your every business requirement. Have Any Questions Regarding Global Agricultural Chelates Market Report, Ask Our Experts@ https://www.advancemarketanalytics.com/enquiry-before-buy/61371-global-agricultural-chelates-market   Strategic Points Covered in Table of Content of Global Agricultural Chelates Market:

Chapter 1: Introduction, market driving force product Objective of Study and Research Scope the Agricultural Chelates market

Chapter 2: Exclusive Summary and the basic information of the Agricultural Chelates Market.

Chapter 3: Displaying the Market Dynamics- Drivers, Trends and Challenges & Opportunities of the Agricultural Chelates

Chapter 4: Presenting the Agricultural Chelates Market Factor Analysis, Porters Five Forces, Supply/Value Chain, PESTEL analysis, Market Entropy, Patent/Trademark Analysis.

Chapter 5: Displaying the by Type, End User and Region/Country 2018-2022

Chapter 6: Evaluating the leading manufacturers of the Agricultural Chelates market which consists of its Competitive Landscape, Peer Group Analysis, BCG Matrix & Company Profile

Chapter 7: To evaluate the market by segments, by countries and by Manufacturers/Company with revenue share and sales by key countries in these various regions (2023-2028)

Chapter 8 & 9: Displaying the Appendix, Methodology and Data Source

Finally, Agricultural Chelates Market is a valuable source of guidance for individuals and companies. Read Detailed Index of full Research Study at @ https://www.advancemarketanalytics.com/reports/61371-global-agricultural-chelates-market What benefits does AMA research study is going to provide?

Latest industry influencing trends and development scenario

Open up New Markets

To Seize powerful market opportunities

Key decision in planning and to further expand market share

Identify Key Business Segments, Market proposition & Gap Analysis

Assisting in allocating marketing investments

Thanks for reading this article; you can also get individual chapter wise section or region wise report version like North America, Middle East, Africa, Europe or LATAM, Southeast Asia. Contact US : Craig Francis (PR & Marketing Manager) AMA Research & Media LLP Unit No. 429, Parsonage Road Edison, NJ New Jersey USA – 08837 Phone: +1 201 565 3262, +44 161 818 8166 sales@advancemarketanalytics.com

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Sustainable Sourness: Tartaric Acid's Growing Role in the Market

Tartaric acid, often found in grapes and other plant sources, is one of the oldest known organic acids, with its roots tracing back to the 8th century. It exists in two forms, d-tartaric acid and l-tartaric acid, each with its own unique properties and applications. What sets tartaric acid apart is its natural origin, which has made it an increasingly attractive choice for industries aiming to meet the growing demand for clean-label and sustainable products. Global Tartaric Acid Market will grow at a 5.6% CAGR during the period 2023–2033 to reach a valuation of US $707.3 million by 2033.

Increasing Demand for Clean Label and Natural Ingredients: Consumers have been increasingly seeking products with natural and clean-label ingredients. Tartaric acid, derived from grapes and other natural sources, fits well with this trend. It has become a preferred choice over synthetic acids and additives in various industries, including food and beverages.

Expanding Wine Industry: The wine industry is a significant consumer and source of tartaric acid. With the global wine industry showing growth, particularly in emerging markets, the demand for tartaric acid as a wine stabilizer and additive was on the rise.

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Pharmaceutical and Cosmetic Applications: Tartaric acid's unique properties have led to its use in pharmaceuticals and cosmetics. Effervescent tablets, creams, and gels formulated with tartaric acid were experiencing demand due to their effectiveness and consumer preference for natural ingredients.

Sustainability and Eco-Friendly Practices: Sustainability has been a significant driver in the tartaric acid market. Industries and consumers are increasingly focusing on environmentally friendly and sustainable practices, and tartaric acid, with its natural origin, aligns well with these values.

Innovation in Industrial Applications: Beyond its use in consumer goods, tartaric acid was gaining recognition for its applications in industrial sectors such as textiles and leather. It was being used to improve dyeing processes, enhance color fastness, and as a chelating agent in metal cleaning and polishing formulations.

Diversification of Applications: Researchers and manufacturers were exploring new applications for tartaric acid in areas such as agriculture, where it can be used as a biodegradable chelating agent for micronutrients, and in the field of green chemistry as a catalyst.

Regulatory Considerations: The tartaric acid market was influenced by regulatory developments, including food safety regulations, quality standards, and labeling requirements, which can impact product formulations and market access.

Supply Chain Resilience: The tartaric acid market, like many other industries, was affected by supply chain disruptions, with fluctuations in the availability of raw materials and transportation challenges impacting pricing and availability.

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Tartaric acid's remarkable versatility, natural origins, and appeal in clean-label products have positioned it for a sweet success in the global market. As industries continue to evolve and consumers seek more sustainable and natural choices, tartaric acid stands ready to meet these demands. With the wine industry's expansion, ongoing innovations in pharmaceuticals and cosmetics, and a steadfast presence in industrial applications, the future of tartaric acid is indeed a promising and sweet success story. It's an exciting era for this organic acid in modern markets, and its growth trajectory shows no sign of slowing down.

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Food Preservatives Market: Rising Concerns over Food Safety and Quality Propel Market Expansion

Food preservatives are substances added to food products to prevent spoilage, maintain freshness, and extend their shelf life. These additives inhibit the growth of microorganisms, such as bacteria, yeasts, and molds, which can cause food to deteriorate. By slowing down enzymatic reactions and minimizing oxidation processes, food preservatives help maintain the nutritional value and sensory qualities of the products. They are widely used in processed meats, dairy products, bakery items, sauces, snacks, and beverages. The use of food preservatives ensures food safety, reduces food waste, and meets consumer demands for longer-lasting and consistently high-quality food products.

The food preservatives market refers to the industry that deals with the production, distribution, and sale of substances used to preserve the quality, freshness, and shelf life of food products. Food preservatives are additives that help inhibit the growth of microorganisms, prevent spoilage, and maintain the nutritional value and sensory attributes of food.

Preservatives are commonly used in various food and beverage products, including processed meats, dairy products, bakery items, sauces, snacks, and beverages. They play a crucial role in preventing microbial contamination, slowing down enzymatic reactions, and minimizing oxidation processes that can lead to food deterioration.

There are different types of food preservatives available, categorized based on their mode of action:

Antimicrobial Preservatives: These inhibit the growth of bacteria, yeasts, molds, and other microorganisms. Examples include sorbic acid, benzoic acid, natamycin, and sodium nitrite.

Antioxidant Preservatives: These prevent the oxidation of fats and oils, thereby extending the shelf life of products containing them. Common examples are ascorbic acid (vitamin C), tocopherols (vitamin E), and butylated hydroxyanisole (BHA).

Chelating Agents: These compounds bind to metal ions, such as iron and copper, which can promote the deterioration of food. Ethylenediaminetetraacetic acid (EDTA) is a commonly used chelating agent.

Natural Preservatives: These are derived from natural sources and include substances like vinegar, salt, sugar, and plant extracts such as rosemary and grapefruit seed extract.

The food preservatives market is driven by several factors, including the increasing demand for convenience foods, changing consumer lifestyles, and the need to reduce food waste. Preservatives help manufacturers meet consumer expectations for longer shelf life, consistent quality, and food safety. Additionally, the growing global population and the expansion of the food and beverage industry are fueling the market's growth.

However, there are concerns regarding the potential health risks associated with certain synthetic preservatives, leading to a growing demand for natural and organic alternatives. Consumer preferences for clean label products, which are free from artificial additives, have influenced the market dynamics, leading to the development of innovative preservative solutions.

Government regulations and guidelines play a significant role in shaping the food preservatives market. Regulatory bodies, such as the Food and Drug Administration (FDA) in the United States and the European Food Safety Authority (EFSA) in Europe, establish maximum limits and safety requirements for preservatives used in food products.

In summary, the food preservatives market is a vital component of the food industry, providing solutions to enhance food safety, quality, and shelf life. The market is driven by factors like consumer demand, industry expansion, and regulatory compliance. Continuous research and development efforts are focused on improving the efficacy and safety of preservatives while addressing consumer preferences for natural and clean label products.

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Research team develops new system for imaging and treating tumors

Research team develops a new system for imaging and treating tumors. May 26, 2023 - Thanks to the radiation they emit, radioactive compounds are suited both to imaging and treating cancers. By appropriately combining them in the novel, so-called radionuclide theranostics, both applications can be dovetailed. A radiopharmacy team at Helmholtz-Zentrum Dresden-Rossendorf (HZDR) and Heidelberg University has now presented such a system in the Journal of the American Chemical Society (DOI: 10.1021/jacs.2c08438) that successfully solves one of the biggest problems to date: it works at physiologically relevant temperatures. “Basically, we can think of it as functioning like a smart key that we use to control our automobiles. We use so-called radionuclides, i.e., unstable atomic nuclei, that spontaneously emit ionized radiation when they decay. We track down the tumor with a diagnostic radionuclide. The targeted internal irradiation close to the diseased tissue is then taken on by a different, therapeutic radionuclide,” says Dr. Manja Kubeil of HZDR’s Institute of Radiopharmaceutical Cancer Research, describing her theranostic approach. Her team in the Department of Radionuclide Theragnostics develops exactly these types of substances to track and destroy tumors. Thus, the researchers employ matched pairs of radionuclides which, due to their decomposition characteristics, can be used both for imaging and for tumor therapy on the same target molecule. The relevant radionuclide is stably bound in what is known as a chelator and linked to a biomolecule by a kind of chemical bridge. “The word chelator comes from the Latin; its stem relates to being encircled by the claws of a crayfish. We prefer the image of a molecular cage that firmly encloses the radionuclide so that it can’t spread in the body uncontrollably. The target-seeking biomolecule for its part must fit perfectly with the docking site on the cancer cells, just like a key in a lock. The radionuclide then accumulates on the tumor tissue and exclusively develops its destructive impact there – that’s the idea,” says Kubeil

Stable bonds at practicable temperatures

Lutetium-177, for instance, is particularly suitable as a beta emitter for releasing electrons to treat various tumors as well as a source of gamma rays for imaging. Actinium-225, an alpha emitter that can be used for efficient treatment, is even more effective in destroying tumors and is also very tightly bound by the chelator. Neither radionuclide occurs naturally on Earth. Appropriate methods have to be used to produce them artificially. Alpha emitters release particles composed of two protons and two neutrons. They are used in cancer therapy because their range in the tissue is very small, but they nonetheless attack and kill cancer cells very effectively thanks to their high energy. Their half-life of seven days in the case of Lutetium-177 and ten in the case of Actinium-225 is ideal for the purpose: it is long enough to enable effective treatment.

New chelator with advantages

So far, there has only been one complexing agent on the market that binds both radionuclides equally well: DOTA. The most frequently used chelator in nuclear medicine is known for its very stable metal complexes. But DOTA has one big disadvantage: only at what are very high temperatures for biochemical conditions, beyond 80 degrees Celsius, is it possible to bond theranostic radionuclides completely. “If you are working with protein derivatives, these temperatures are way too high because even at 40 degrees Celsius denaturation kicks in: they are destroyed. Our new chelator system functions reliably at these lower temperatures,” Kubeil is pleased to report. Moreover, under these milder conditions, it achieves faster radiolabeling than the known chelators. Another advantage is that the new system efficiently attaches to various bioconjugates. This means an increase in the choice of docking sites on diseased tissue. The newly developed chelator could thus form the basis for new modular and personalized pharmaceutical systems that could be geared towards different fields for imaging and therapy by simply exchanging partial chemical structures. Publication: P. Cieslik, M. Kubeil, K. Zarschler, M. Ullrich, F. Brandt, K. Anger, H. Wadepohl, K. Kopka, M. Bachmann, J. Pietzsch, H. Stephan, P. Comba, Toward Personalized Medicine: One Chelator for Imaging and Therapy with Lutetium-177 and Actinium-225, Journal of the American Chemical Society, 2022 (DOI: 10.1021/jacs.2c08438) Read the full article

[mitivy]

CAS NO.80-62-6 High quality Methyl Methacrylate（Mma) supplier/High quality/Best price/In stock have REACH Certification

Quick Details Product name:Triethylenetetramine (TETA) CAS:112-24-3 Molecular formula:C6H18N4 Molecular weight:146.23 EINECS No.:203-950-6 Density: 0.982 g/cm³ Melting point: 12 ℃ Flash point: 135°C Boiling point: 266-267 ℃ Appearance: Colorless to light yellow viscous liquid Solubility: Miscible with water, slightly soluble in ether, soluble in ethanol, acid Properties: yellow liquid with strong alkalinity and medium viscosity, its volatility is lower than that of diethylenetriamine, but its properties are similar Other names：Triethylenetetramine;TETA;N,N'-DI(2-AMINOETHYL)ETHYLENEDIAMINE;Ethylenediamine;2,2,2-tetramine;N,N-Di(2-Aminoethyl)Ethylenediamine;TRIETHYLENETETRAAMINE;Trientine;N1,N1'-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) Purity:≥99% Brand:MIT -IVY INDUSTRY CO.,LTD Port: any port in china Packing:according to the clients requirement Storage: Store in dry, dark and ventilated place. Transportation: by sea or by air payment methods: L/C, T/T, D/A, D/P, O/A, paypal, western union etc.accept all payment. Certificate of Analysis Product:三乙烯四胺-Triethylenetetramine(TETA) CAS:112-24-3 Inspect Date: 2022.07.25 Production Date:2022.07.25 Quantity: 20T Batch No.:MITSC22073112 Shelf life: Five years Test Item And Results Item Results  Method Sales Seecification Appearance colorless or pale yellow Assay (water free)    % 99.0 ST35.219 97.0-100.0 Color Platinum/Cobalt 20 ASTM1209 0-50 Water content  % 0.10 ASTME203 0.00-0.50 Amines, mol.Wt 0.15 ST35.219 0.00-2.00 Conclusion Qualified Application 1. Used as synthetic resin curing agent, additive, fabric finishing agent, etc. 2. Used as a complexing agent, alkaline gas dehydrating agent, dye intermediate, resin solvent and rubber accelerator 3. In addition to being used as a solvent, it is also used in the manufacture of epoxy resin curing agents, rubber additives, emulsifiers, surfactants, lubricating oil additives, fuel oil cleaning and dispersing agents, gas purifiers, cyanide-free plating diffusion agents, brighteners , detergents, softeners, metal chelating agents, and synthetic polyamide resins and ion exchange resins. 4. Complexing agent, cleaning agent, softener, dye synthesis, rubber accelerator, gas dehydration purifier. Our Service 1. Best quality in your requirement 2. Competitive price in china market 3. Mature technical support 4. Professional logistic support 5 . Full experience of large numberscontainers loading in chinese sea port 6 .Fast shipment by reputed shipping line 7. Packing with pallet as buyer's special request 8. Best service after shipment. 9.  Full experience in export 10. Raw materials from chinese origin Company Information MIT-IVY INDUSTRY CO.,LTD is a manufacturer and exporter of fine chemical dyes & pharmaceutical intermediates in China. Mainly produce aniline series products and chlorine series products. We are a young company full of vitality and vitality. The company has a group of energetic, well-trained employees and strong technical research and development capabilities. We specialize in the production, development and sales of API intermediates, fine chemicals and plant extracts. Relying on advanced equipment and strict management, adhere to the business philosophy of "openness, tolerance, innovation, and sharing" to create a win-win cooperationplatform.Everything comes from innovation, it is our philosophy ! If you are interested in getting more quotations, please add WHATSAPP:0086-13805212761 or E-MAIL:info@mit-ivy.com MIT-IVYINDUSTRYCO.,LTDMit-Ivy is a well-known fine chemicals and pharmaceutical intermediates manufacturer with strong R&D support in China. Mainly involved Aniline, Chlorine products. Payment：DA 60 DAYS TEL:008619961957599   E-MAIL:info@mit-ivy.com 产品 Product CAS N,N-二甲基-1,4-苯二胺 N,N-Dimethyl-1,4-phenylenediamine DMPD 99-98-9 N,N-二甲基苄胺 N,N-Dimethylbenzylamine  BDMA 103-83-3 N,N-二甲基甲酰胺   N,N-Dimethylformamide  DMF .68-12-2 N,N-二甲基甲酰胺二甲缩醛 DMF-DMA N,N-Dimethylformamidedimethyl acetal  (DMF-DMA) 4637-24-5 N,N-二甲基乙酰胺 N,N-Dimethylacetamide   DMAC 127-19-5 N,N-二乙基间甲苯甲酰胺 避蚊胺 N,N-diethyl-m-toluamide    DEET 134-62-3 N,N-二乙基羟胺 N,N-Diethylhydroxylamine  DEHA 3710-84-7 N-甲基-N-羟乙基苯胺 2-(N-甲基苯胺)乙醇 2-(N-methylanilino)ethanol 93-90-3 N-甲基吡咯烷酮 N-methylpyrrolidone 872-50-4 N,N-二甲基苯胺 N,N-Dimethylaniline   DMA 121-69-7 N,N-二甲基对甲苯胺 N,N-Dimethyl-p-toluidine  DMPT 99-97-8 N,N-二甲基邻甲苯胺 N,N-Dimethyl-o-toluidine   DMOT 609-72-3 N,N-二乙基苯胺 N,N-Diethylaniline 91-66-7 N,N-二乙基间甲苯胺 N,N-Diethyl-m-toluidine 91-67-8 N,N-二羟乙基苯胺 N,N-Dihydroxyethylaniline   PDEA 120-07-0 N-乙基间甲苯胺 N-乙基-3-甲基苯胺 N-Ethyl-m-toluidine/N-Ethyl-3-methylaniline 102-27-2 N-乙基-N-氰乙基苯胺 3-(N-ethylanilino)propiononitrile 148-87-8 N-乙基-N-羟乙基苯胺 N-Ethyl-N-hydroxyethylaniline 92-50-2 N-乙基-N-苄基苯胺 乙基苄基苯胺; N-苄基-N-乙基苯胺 N-ethyl-N-phenylbenzenemethanamine 92-59-1 N-乙基-N-氰乙基间甲苯胺 N-2-cyanoethyl-N-ethyl-m-toluidine 148-69-6 N-乙基-N-苄基间甲苯胺 N-Benzyl-N-ethyl-m-toluidine 119-94-8 N-乙基邻甲苯胺 N-Ethyl-o-toluidine/2-Ethylaminotoluene 94-68-8 N-乙基苯胺 N-Ethylaniline 103-69-5 N-甲基苯胺 N-Methylaniline 100-61-8 N,N-二甲基-间甲基苯胺 N,N-DIMETHYL-M-TOLUIDINE 121-72-2 N-甲基二苯胺 N-Methyldiphenylamine 552-82-9 N-甲基-邻甲基苯胺 N-METHYL-O-TOLUIDINE 611-21-2 N-甲基-对甲基苯胺 N-METHYL-P-TOLUIDINE 623-08-5 4-甲基-N-苯基苯胺 N-PHENYL-P-TOLUIDINE 620-84-8 N-异丙基苯胺 N-ISOPROPYLANILINE 768-52-5 N,N-二氰乙基苯胺 N,N-Dicyanoethylaniline 1555-66-4 N,N-二羟乙基-对甲基苯胺 N,N-DIHYDROXYETHYL-P-TOLUIDINEDHEPT .3077-12-1 N-乙基-2-硝基苯胺 N-Ethyl-2-Nitro-Benzenamine 10112-15-9 2,4-二氯苯胺 2,4Dichloroaniline 554-00-7 N-(2-羟乙基)乙二胺 AEEA 111-41-1 1,3-二甲基-2-咪唑啉酮N,N-二甲基亚乙基脲1,3-二甲基-2-咪唑啉酮（DMI) 1,3-Dimethyl-2-imidazolidinone  DMI N,N'-dimethylimidazolidinone 80-73-9 N,N-二苄基羟胺 N,N-Dibenzylhydroxylamine 621-07-8 对甲苯胺 P-Toluidine  PT 106-49-0 邻甲苯胺 O-Toluidine  OT 95-53-4 甲萘胺 AlphaNaphthylamine 134-32-7 间二氯苯 1,3-Dichlorobenzene   MDCB 541-73-1 间甲苯胺 M-Toluidine  MT 108-44-1 间苯二胺 M-PHENYLENEDIAMINE  MPD 108-45-2 多乙烯多胺 PEPA 68131-73-7 二乙烯三胺(DETA) Diethylenetriamine  DETA 111-40-0 三乙烯二胺 Triethylenediamine 280-57-9 三乙烯四胺 TriethylenetetramineTETA 112-24-3 四乙烯五胺 TEPA 112-57-2 二乙基乙醇胺 DEEA;DEAE 100-37-8 Read the full article

[blueweave8]

Sodium Thiosulphate Market Scope, Growth, Insight

BlueWeave Consulting, a leading strategic consulting and market research firm, in its recent study, estimated global sodium thiosulphate market size at USD 104.75 million in 2022. During the forecast period between 2023 and 2029, BlueWeave expects global sodium thiosulphate market size to grow at a significant CAGR of 6.1% reaching a value of USD 158.02 million by 2029. Major growth factors for global sodium thiosulphate market include increasing product demand in the healthcare and medical industries, growing healthcare and medical sector and advancements in these sectors. Similarly, the rising prevalence of chronic kidney failure illnesses, particularly calciphylaxis, is expected to drive demand for sodium thiosulphate. According to reputable estimates, calciphylaxis affects 1% to 4.5% of dialysis patients, with the majority of patients being diabetic, obese, or suffering from chronic liver disease. For the treatment of calciphylaxis, sodium thiosulphate serves as an antioxidant and calcium chelating agent. Also, developing mining operations in various regions, such as North America and Asia Pacific are paving the way for the sodium thiosulphate market in the coming years. According to Gold.org, global gold mining contributes around 2,500 to 3,000 tons of gold to the total above-ground supply of gold each year. Therefore, these factors are expected to boost the expansion of global sodium thiosulphate market during the period in analysis. However, increasing cost of the raw materials is anticipated to restrain the market growth.

Global Sodium Thiosulphate Market – Overview

Sodium thiosulphate is a colorless inorganic sodium salt that dissolves readily in water. It is made up of sodium and thiosulfate ions in a 2:1 ratio. It is used in the treatment of photographic paper and films. Prior to discharge into the environment, sodium thiosulphate liquid is employed to de-chlorinate ballast waters. The increasing use of sodium thiosulphate for heavy metal removal from industrial wastewater is estimated to drive the global sodium thiosulphate market size during the forecast period. Rising demand for sodium thiosulphate from the healthcare sector for the creation of antidotes used to treat cyanide poisoning contributes to market expansion. Sodium thiosulphate is widely used in gold extraction. This compound is also employed as a cyanide replacement lixiviant. In iodometry, sodium thiosulphate is employed as a measurement agent for oxygen in water for approximating substances such as hydrogen peroxide. This is expected to boost the sodium thiosulphate market overall throughout the forecast period. Consumers' growing worry about their health is expected to benefit the whole market during the next seven years. Another key end-use business is water treatment. It is used to reduce chlorine levels and to treat settled backwash water in swimming pools, spas, and aquarium.

Sample Request @ https://www.blueweaveconsulting.com/report/sodium-thiosulphate-market/report-sample

Global Sodium Thiosulphate Market – By Application

Based on application, global sodium thiosulphate market is divided into Medical, Photographic Processing, Iodometry, Gold Extraction, and Water Treatment segments. The water treatment segment held the highest market share. Sodium thiosulphate neutralizes chlorine, avoiding additional bactericidal effects on organisms in transit water. It also forms soluble complexes with heavy metals like lead, mercury, arsenic, and cadmium, making it easier to remove them from industrial waste effluents. Heavy metals are carcinogens, which can destroy the lungs, liver, kidneys, and other important organs. As a result, rising health concerns and demand for freshwater drive the sodium thiosulphate industry forward. According to the Organization for Economic Cooperation and Development (OECD), worldwide freshwater consumption is expected to rise by 55% between 2000 and 2050. It, in turn, is expected to boost the growth of the water treatment segment.

Competitive Landscape

Major players operating in global sodium thiosulphate market include Esseco SRL, Galactic, Allan Chemical Corporation, Samirian Chemicals Inc., Noah Chemicals, Dastech, INEOS, DBWINC, Southern Ionics Incorporated, Skyhawk Chemicals, Inc., Liyang Qingfeng Fine chemical Co. Ltd, Changsha weichuang chemical Co. Ltd, and Haimen Wuyang Chemical Industry Co. Ltd. To further enhance their market share, these companies employ various strategies, including mergers and acquisitions, partnerships, joint ventures, license agreements, and new product launches.

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[mystictyrantrunaway]

An Introduction To Lakadong Turmeric Powder

In Pakistan, you can find numerous cuisines operating and The majority of them have access to the grocery objects which have been typically obtainable. Regrettably, the grocery section and also the fruits and vegetables on line current market are saturated with adulterated stock and that poses a serious threat towards the well being of your Pakistanis. We have to do some thing to beat The problem of food stuff adulteration prior to it is too late.

With regards to turmeric well being Rewards and encouraged day-to-day amount of intakes, there are various uncertainties. In this article you are able to learn about the feasible Added benefits, Unintended effects and uncertainties a few suggested dosage.

The turmeric spice is amongst the crops that were used in Ayurvedic medicine, the normal exercise in India that remains to be current to at the present time. Scientific evaluation has demonstrated the "Lively" components on the https://en.wikipedia.org/wiki/?search=lakadong turmeric spices are classified as the curcuminoids, most notably curcumin.

Curcuminoids are answerable for the yellowish orange color of the root. Scientists have figured out the compounds answerable for the varied colors of plant foods act as antioxidants from the human body. A number of them have other activity, in addition.

That delivers us into the turmeric wellbeing benefits and proposed daily quantity. Laboratory screening has concluded that curcumin has chelating, antioxidant, anti-tumor, anti-arthritic, anti-amyloid, anti-ischemic, anti-coagulant, anti-inflammatory, anti-diabetic and anti-most cancers exercise. All of it Seems excellent, but there's a problem.

As being a drugs, it absolutely was historically utilized to for belly ailments, for example ulcers, heartburn, irritable and inflammatory bowel. It had been also believed to "fortify" the liver, which has been supported by some fashionable reports. All of the other things that are at this time remaining investigated have to have that curcumin receives towards the bloodstream, but it's swiftly degraded by abdomen acid. Scientists have concluded that top doses, about ten grams or 10,000 mg never considerably increase the quantity of curcumin during the bloodstream.

Researchers consult with this as minimal bio-availability and it is without doubt one of the reasons the turmeric well being Gains and suggested everyday quantity of ingestion are uncertain. You may think that a better dose would be better, but large doses are accompanied by undesired Uncomfortable side effects, together with nausea and stomach upset. There are actually other undesirable side effects which i'll reach inside of a second, but 1st, Let's take a look at The solution to bioavailability.

The particular answer would be to have a average dose, fifty-100mg, increase an enteric coating to guard it from abdomen acid and contain other plant compounds that lakadong turmeric benefits enhance its bioavailability. An enteric coating cuts down the risk of tummy upset, also.

Taking any anti-coagulant is accompanied by threat, significantly Should the dosage is simply too large. One example is, daily aspirin intake is frequently suggested for those who have had coronary heart attacks, due to the anti-coagulant influence, nevertheless the advisable dose for an adult is about what you would locate in toddler aspirin.

That's 1 explanation that there are questions about the turmeric wellness Positive aspects and recommended daily quantity. Anti-coagulants avoid the blood from clotting when There may be an injuries. Yet another possibility has to do Using the chelating activity. Chelating brokers help the human body rid alone of harmful large metals, but might also interfere with iron metabolism, which could cause anemia, in inclined people today.

There's no question there are turmeric health Added benefits and advised each day number of intake that does not exceed 50-100mg is Risk-free. Anything at all increased is risky. The ideal nutritional supplements comprise this total, in addition to a variety of other plant extracts, along with simple vitamins and minerals.

[leeb57555]

Organic Trace Minerals Market Present Scenario And The Growth Prospects 2030

Trace minerals play a vital role in several metabolic functions in the animal body. These minerals can be derived from organic as well as inorganic sources. Inorganic trace minerals, such as sulphates, carbonates, chlorides, and oxides of elements, interact with tannin, fiber, silicates, oxalate, phytate, and other minerals in the gastrointestinal tract of animals, thereby affecting the feed absorption process. As organic trace minerals such as selenium, zinc, copper, and manganese improve gut absorption in animals, they are being increasingly used in animal feed.

As organic trace minerals also include iron, the surging iron deficiency among poultry and ruminants will help the organic trace minerals market register significant growth in the coming years. Additionally, the mounting focus of animal farm owners on strengthening animal immunity will create a huge requirement for minerals such as copper and manganese in the foreseeable future. Furthermore, the surge in the number of animal farms is propelling the demand for organic trace minerals, as veterinarians are increasingly recommending using these products in animal feed.

Thus, the burgeoning demand for animal products, such as milk and meat products will augment the usage of organic trace minerals in the forthcoming years. The quantity and quality of animal products largely depend on the type of feed they consume. Zinc and iron-based animal feed are the most prominent products being prescribed by veterinarians, owing to their beneficial medical properties. Even though these products are fed in small quantities, they play a pivotal role in the maintenance of the health and productivity of animals.

According to the Association of American Feed Control Officials (AAFCO), metal (specific amino acid) complexes, metal amino acid complexes, metal proteinates, metal amino acid chelates, metal propionates, metal polysaccharide complexes, and yeast derivative complexes are the various types of organic trace materials that are being used to enhance animal productivity and improve animal health. These products also help in increasing milk quality, enhancing reproductivity, and facilitating animal growth. Additionally, organic trace minerals are also used to improve the growth performance of birds and enhance meat characteristics.

At present, organic trace minerals are offered by Tanke Biosciences Corporation, Cargill and Kemin Industries, Royal DSM NV, and Zinpro Corporation. These companies prepare amino acid chelates of trace minerals by mixing a 2:1 molar ratio of amino acid preferably methionine with inorganic trace mineral ions. Nowadays, organic trace mineral manufacturers are increasingly focusing on research and development (R&D) activities in order to develop better products to attract more animal farm owners. As zinc-based animal feed is being consumed in the highest quantity, these companies are primarily focusing on the production of zinc laden animal feed.

According to P&S Intelligence, North America dominates the organic trace minerals market, due to the surging customer awareness about the advantages of organic products in the region. Additionally, the implementation of stringent environmental regulations is limiting the use of inorganic minerals, which is, in turn, fueling the adoption of organic trace minerals in the region. Furthermore, the Asia-Pacific (APAC) region is also adopting a considerable volume of organic trace minerals, due to the soaring consumption and export of milk products and meat in the region. Thus, the rising emphasis on animal health and enhanced productivity, escalating demand for milk products and milk, and growing prevalence of iron deficiency among animals will encourage the use of organic trace mineral products in the coming years.

[acelessthan3]

given that I work in the supplement industry with ease of access, product information, a lot of reading time, and willingness to experiment on my own body; I guess you could say I’m an amateur biohacker 

so I’ma lay some knowledge on you

guess if I’m gonna be thorough

first off: don’t trust everything you read on the internet, but if you’re going to examine and selfhacked are two reputable, well-researched, well-sourced places for information on any given nutritional supplement. I’m more inclined to trust examine if I have to choose between the two. If they don’t have an article on it, there probably hasn’t been enough science done to warrant putting it together.

that said, just because science doesn’t have something to say about a thing, doesn’t mean it doesn’t work in some way, just means science hasn’t done the work to look at it yet and Traditional Chinese Medicine, Ayurvedic Traditions and various Indigenous Peoples’ herbal remedies have merit and are worth looking at

I’m also not a doctor, but I’ve got a BS in Kinesiology so I’ve taken enough anatomy and biochemistry to at least be able to read most of the science I come across. I also work as a supplement whore and have years of customer interactions and corporate product trainings to know what’s hot in the industry, what the trends are for consumers, what doctors and naturopaths most frequently recommend.

Here’s my go-to supplements:

Vitamin D

This one’s in the news a lot lately. The science is all over the place, but chances are if you’re in a Western country that isn’t tropically or sub-tropically located and don’t work outdoors in very little clothing, you probably need at least some Vitamin D. It’s important in immune function, calcium absorption, mood and actually quite a few other things that are still being investigated. I come from Pacific Islander genetics (I’ve got melanin y’all) and live near the Canadian border, I find it helps me with Seasonal Affective Disorder symptoms. Unless specifically stated to be vegan, most D will be sourced from lanolin (the fatty substance from sheep’s wool) in softgels with a sunflower/canola carrier oil.

Nitric Oxide Boosters

There’s actually a lot of these that work in different ways, but science is finding that nitric oxide levels in the blood are part of how the body maintains healthy blood pressure. Nitric oxide in the body relaxes smooth muscles which increases the diameter of blood vessels, increasing blood flow. It’s part of how your body lowers blood pressure post-exercise.

There’s several ways (supplementally speaking) to increase nitric oxide in the body. The easiest is to increase available nitrates. As nitrates are digested, they, you guessed it, increase nitric oxide in the blood. Some supplementally available sources of nitrates include: beet root (powder or capsules) and leafy greens.  Synthetic forms like potassium nitrate also exist.

Another way to increase nitric oxide is to use the other metabolic pathways providing appropriate chemical precursors to aid in those biological functions. The most common is L-Arginine. L-Arginine is an amino acid that gets converted into nitric oxide. It’s also used in muscle protein synthesis. It’s in nuts and seeds and meat, and can be supplemented as a standalone molecule. Bioavailability (how well your body can absorb it) is limited as a supplement though because a lot gets broken down in the gut before it can hit the bloodstream, and it’s frequently paired with L-Citrulline (a different amino acid found in high amounts in watermelon) which is converted to arginine in the body but doesn’t get broken down before being absorbed. Aged Garlic Extract (capitalized because it’s a trademarked version that has specifically been studied) works on this by upregulating nitric oxide synthase (which is just fancy for nitric oxide-making enzyme).

Any sports/bodybuilding product that talks about increasing muscle pump is probably using at least one ingredient that affects nitric oxide levels. For dudes, any reputable supplement marketed for “blood flow” will contain at least one ingredient that affects nitric oxide levels (also a lot of the ingredients in those same products are also marketed as “testosterone boosting” ingredients actually do have uses as nitric oxide boosters if you look at the science). And by reputable I mean you won’t find it at a gas station.

There are various other herbs and things that some studies have shown to affect nitric oxide levels, they’re not as common and/or don’t have much research backing them up, but I’ll list a bunch. Pycnogenol, Horny Goat Weed (epimedium grandiflorum), Grape Seed Extract, Ginseng Tribulus Terrestris. Antioxidants like Resveratrol (a polyphenol originally derived from red grape skins), Glutathione, CoQ10. 

Magnesium

It’s like super important in the body. It’s like the fifth most common element in the human body and is an essential electrolyte for muscle and nerve function. Food sourcing is always best, but there’s arguments to be made that because of corporate monoculturing and depletion of topsoil, that contemporary foods are much lower in minerals than they were pre-industrial. So supplemental. There’s a ton of different types. The way I explain it, pure, metallic magnesium isn’t very useful to the body, so as a supplement you have to chelate (chemistry speak for react it) it with... something. Magnesium oxide is the cheapest (with oxygen). It’s the least bioavailable, but also has the highest elemental Mg of all the chelates. Magnesium Citrate is probably the next most common/cheapest. It’s mixed with citric acid. Take too high a dose of either of these at once and it will cause an electrolye imbalance in your gut. Basically your gut goes hey there’s too much salt in here (and magnesium chelates are salts) and draws a bunch of water into your intestines to flush it out. Sometimes prescribed to treat constipation. The next class are your amino acid chelates. Glycinate, Taurate, Threonate, to name a few. Research is still emerging, but different amino acids get the magnesium to different parts of the body and they have slightly different effects. They’re the most bioavailable because the human body is designed to recognize and digest proteins to amino acids. Magnesium chloride (or ionic) is going to be salt water derived with the sodium salt removed. I personally take a ZMA form, which is Zinc Magnesium Aspartate (with B6) specifically because it’s been well-studied in athletes for promoting restful sleep. I’ve also done a mag citrate in powdered drink form and found that it helped prevent cramping and somewhat mitigate my nighttime bruxism.

Nootropics to control your mood

So there’s all the caffeine and brain performance enhancers. I’m not really into that. A lot of products for memory and focus specifically have herbs and other ingredients that at least some studies have shown increase blood flow to the parts of the brain that help with... memory and focus. Those will be your Huperzine A, Bacopa, Ginkgo Biloba, Rosemary and, well, anything I mentioned above under nitric oxide boosters because more blood flow! I guess the Lion’s Mane Mushrooms would be in this class of nootropics. 

Another class of nootropics are your “Brain Foods” these are direct chemical precursors to various neurotransmitters in your brain. The idea being that if you give your brain more of the raw materials it needs to make serotonin, acetylcholine, gaba or dopamine, it will make them. There’s a bunch and I forget exactly which ones go with which, but L-Tyrosine, TMG (trimethylglycine), L-Phenylalanine, L-Tryptophan (and it’s own metabolite 5-HTP), Acetyl-L-Carnitine, Alpha GPC, L-theanine, GABA, L-Citrulline, L-DOPA (and in plant form as mucuna pruriens).

The one that I recommend most often is L-theanine. It’s an amino acid derived from green tea. It’s part of why the caffeine in tea doesn’t make you as jittery as the same amount of caffeine from coffee. L-theanine is a direct chemical precursor to GABA which is the neurotransmitter most active in the parasympathetic nervous system (aka, the rest and digest nervous system). It’s like a literal chill pill when it comes to acute anxiety and works within like half an hour. You can also get GABA by itself.

You also have your adaptogens, which are a classes of herbs that help balance your hormones and “adapt” to stress. Ashwaganda, rhodiola, various ginsengs, tulsi “holy basil” and I’m sure several others I’m forgetting. Most are from ayurvedic or TCM uses.

There’s also CBD which helps some people with anxiety. The kind you can find at supplement stores or health food stores will be hemp-derived, which means by under the 2018 Farm Bill it cannot contain more than 0.3% THC by weight or it is classified as a marijuana/cannabis product and therefore illegal federally.

Sleep

I don’t fuck with melatonin. Most healthy bodies with an uninterrupted circadian rhythm naturally produce less than 0.3mg of melatonin at night so all these sleep supplements with 1, 5, TEN mg of melatonin kind of scare me and I always try to steer people to a lower dose first unless they’re coming in on doctor’s orders. 

GABA and L-theanine because they’re calming can be helpful for sleep if the problem is turning off your brain. They’re non-sedative on their own but can be helpful. 

Magnesium also relaxes the body and can be helpful for sleep.

CBD and Ashwaganda for their stress-relieving properties are frequently marketed for sleep. 

Herbally there’s valerian, st john’s wort, poppy and kava kava. The risk of complications or potential interference with medications are why I don’t recommend these ones first unless someone is specifically looking for them. Lavender, chamomile, hops, and catnip are all usually pretty safe and common in herbal blends.

Homeopathy

I don’t trust homeopathy. The idea that small amounts of a thing that would normally cause the symptom you’re trying to treat makes sense. That’s the same principle behind inducing an immune response with vaccines. The idea that the more you dilute the thing, the more powerful it’s action in the body? Sketchy at best. The idea that the water used to dilute the thing will remember it so even if the dilution is so massive that there are no actual molecules of the original substance in a hundred pills (that are also, for the record, dry)? You lost me.

That said, surgeons do recommend 6C or 10X Arnica after surgery for bruising and it does seem to lessen the heal time.

Yeah, if you have questions on anything specific, feel free to shoot me an ask. If I don’t know off the top of my head, I can find out.

[bleedingcoffee42]

Eureka AU - Part 9

Weeeeee...here we go.  Future Me is going to be so happy when she edits this and has to make up entire fields of shitpost science.  Hahaha.  

Part 1, Part 2, Part 3, Part 4, Part 5, Part 6, Part 7, Part 8

xxxxxxxxxxxxxxxxxxxxxx

Ed's eyes shifted over to Mustang who now sounded a lot more like the boss they all knew.  His statement was an order, it wasn't a discussion starter, and Al was already reprogramming his tiny robots to do as asked.    He had to admit, it was good to feel like the condescending asshole was back to being himself because they genuinely needed him.

“That would avoid sending her into shock when you kill a massive load of invasive pathogens in her body.”   Knox said.  He was here to remind everyone his patient was human and this wasn't a simulation. Killing a large quantity of anything in her bloodstream could very well have consequences they were not planning for.   In theory a lot of things sounded good, but they were just desperately looking for any idea that could work at this point and that was not how he practiced medicine.   “I do like the idea of giving the virus something else to attack, that will give her own immune system a chance to fight back as well.”

“How are we going to get the nanites out of her system?”  Marcoh asked. “Now they're going to be twice as big, if not bigger, and she's already lost blood?”

Ed watched Mustang stand up, his focus seemed to have returned and his attitude noticeably changed.  He was back to commanding everyone's attention in the room, they all looked to him even though he hadn't made a sound to indicate he had an answer.  

“Chelation.” Roy said as if the answer was simple and had been there the entire time.   “Dr. Comanche has a project that is meant to extract metals from the blood stream, more than just the common treatment for lead and mercury poisoning.   It's been approved for medical use, extensive testing already.   Last proposal he submitted to me implied he was able to use it to extract valuable metals from any source.   He's trying to market it to me as a way to clean waterways of mercury, but his research paperwork tells me he's also looking to harvest more valuable non-toxic metals in the process.“

Ed saw where Mustang was going with this.  “So he has the equipment to synthesize an amino acid to do his bidding in his lab?”

Roy pulled his keys out of his pocket and held them up.  “Shall we?”

Ed smiled and together they left Al's lab to go take what Comanche had available.  Under any other circumstances he would be delighted they were pillaging his colleagues labs and utilizing the incredible array of resources in this building for good.   Right now he was just happy it was here and they were able to take advance of years of research to save someone they all held dear.   He ran over to the elevator to hit the button and open it for them both to head to the next floor. “So what tipped you off about Comanche?”

  “He clearly doesn't think my field of Thermodynamics includes equilibrium thermodynamics because he might as well have highlighted all the documentation of his side project in the proposal he submitted to me.”

“Not to defend the guy, cause he's a dick, but you are notorious for not looking at paperwork.”  Ed reminded him.  Mustang looked over at him and smiled, a smug smile, that made him think that that was a ruse.   The asshole did read everything.  

“In this instance, I thought it best to catch him harvesting his retirement income from the polluted streams instead of trying to prosecute him based on theoretical research that not judge is going to understand.”   Roy replied.  

“Or let him collect next years budget for you since his inventions are contractually property of the government while he's working in this facility.”   Ed countered.

“You have no idea how much this place costs to keep running.”  Roy said and the doors to the elevator closed and they went up to the next floor.  “You especially cost a lot of money.”

“We might not have to beg for Congressional pocket change if you spent more time being a scientist and less time as a politician.”  Ed said to him and Mustang narrowed his eyes at him.  

“There is honestly nothing good that will come from any projects I create with my specialty.”  Roy said.  “I've come to that conclusion long ago.  I'll do more good filtering what the government sees and receives from Eureka.”

“Like the flame-thrower gloves you keep in your desk?”

“Stop breaking into my office.”   Roy hissed as the bell dinged indicating they were on the next floor.   Ed snorted, as if it was his right.   Fine.  He'd put an end to that.  “I have sex with my wife on that desk.”

“What the fuck, Mustang?”

Roy smiled and stepped off the elevator and walked down the hall to Comanche's lab, room 047.   He unlocked the door and turned on the light.   Together he and Ed started turning on equipment and looking for what they needed.  “Comanche used his biological advancements in the field to get himself hired here, now he's focusing on environmental uses for his research.   I suspect he's doing that to not only gain favor within the community here, which is by nature rooted in finding cleaner and less invasive ways of doing things, but also to divert attention from what he may be doing with his original research.”

Ed was already diving into the files on the computer.    There was a lot of information here and it backed up Mustang's theory that Comanche was a really busy guy.   “Well that would explain how a dude his age can hop around on that peg leg like he's a ballerina.  He's using Chelation to clean his own  body of the wear and tear of aging.  I thought that was bullshit pseudo-science.”

“What's commercially available, yes..”  Roy said and turned on the machine that was used to synthesize the amino acids for the particular task needed.   There were profiles in the computer already for the standard uses of cleaning lead, mercury and arsenic from the body.   There was more though and Roy opened them up to see each to consider the formulas.   “EDTA for cleaning his clogged arteries and another for his joint arthritis.”

“Glad he's testing that on himself but I think keeping the obvious advances to himself is bullshit.” Ed shook his head.  “I see what you're saying about his environmental project.   Someone is a naughty alchemist, pulling lead out of the water and with it- gold.”

“He's probably old enough to have called himself an alchemist.”  Roy replied and heard Ed chuckle.   “I'm sure he's hiding it all so he can diversifiy his retirement fund,  quite the windfall when he takes this to the private sector.   I don't feel bad at all for breaking in here to use it for my own personal reasons.”

“It's personal for all of us too.” Ed said.  “Hawkeye is the best thing to happen to this town in a long time.”

“I'm well aware that if our little feuds ever came to taking sides that this town would have all stood behind her.”  Roy said, thankful that those days were behind them but also with a touch of nostalgia for the rivalry they had started with.  She made him work to outmaneuver her and that was something he couldn't say of a lot of people.  

“Alright, I have something promising here.   Let me upload Al's data and see about making us something. Metallurgy is a specialty of mine I got this.”  Ed said and connected his tablet to the computer and started to work his magic.  

“How is your brother going to handle us targeting his nanites and neutralizing them with this? I'm basically having you classify them as a toxin to have them broken down and flushed down the drain.”  Roy asked.   He didn't want to mention the Ultimate Eye tech they had thrown into the tank that was going to be destroyed with them.     He'd figure out that later.

“Al's not selfish, he understands that the sacrifice is worth it.   It's a setback, but he's patient.” Ed said and kept typing.   Heavy metals and elements were a breeze for him, he barely needed to focus to re-calibrate the program.   “Besides I'm sure he's discussing a catheter and collection bag with Knox as we speak.   Nothing gets flushed down the drain.”

“Riza will be thrilled to hear he's called 'dibs' on her piss.   Life in Eureka never ceases to keep her guessing.”  Roy said and saw data being transferred to the machine he was staring at.  Ed was fast.    He looked at the time and realized it wasn't even midnight yet.  It felt like they had been here forever, that he'd lived a few lifetimes between carrying Riza into the infirmary around 1800 and now.   This was a glimpse of her job, what happened when he was away.   This was why she was so adamant of being read in on everything that had the potential to go to hell, because when it did it was a race to stop a catastrophe.   They played on a whole different playing field here, science without regard to established rules and so often bordering on playing God. When it went wrong, it went horribly wrong.  They had so much they still needed to talk about and he hoped he got the chance.

“She'll be pissed.” Ed snorted and Mustang shot him a look.  “She hates sitting out.”

“That she does.”   Roy said and looked at the screen.  They were ready to begin synthesizing the next step in the process.  

[clairemaggie]

What does ergothioneine do to the skin?

What is l-ergothioneine?

Ergothioneine (mercaptohistidine trimethyl inner salt, ergothioneine, EGT) is a natural antioxidant that can protect cells in the human body and is an important active substance in the body. Natural antioxidants are safe and non-toxic, and have become a research hotspot. As a natural antioxidant, ergothioneine has entered people's field of vision. It has various physiological functions such as scavenging free radicals, detoxification, maintaining DNA biosynthesis, normal cell growth and cellular immunity.

Ergothioneine is distributed in some tissues and organs of mammals, mainly in red blood cells (about 1-2 mmol.L) and the semen of some animals. Although no experimental studies have shown that animals can synthesize this substance, but There must be pathways for the absorption and retention of ergothioneine in animal cells. For carnivores, ergothioneine in animal tissues can supply dietary needs.

The essence of ergothioneine is a natural and rare amino acid, which was first discovered by French pharmacist Charles Tanret in 1909 when investigating the ergot fungus Claviceps purpurea, and then scientific research found that ergothioneine also exists in human and other animal tissues.

Since ergothioneine was discovered in animal tissues, scientists have conducted more in-depth research on ergothioneine and found that it can effectively scavenge free radicals (the main factor causing human aging), protect cell membranes and mitochondrial membranes from immune Various functions such as oxidative damage, cell protection and anti-ultraviolet radiation.

What does ergothioneine supplement do to the skin?

The cosmetics industry is the most widely used field of ergothioneine. In recent years, one of the important driving forces for the rapid development of China's ergothioneine market is because of the wider application of ergothioneine in the cosmetics industry.

The main role of ergothioneine in the skin care industry is to whiten and remove freckles and act as an antioxidant. With a risk factor of 1, it is very safe, non-comedogenic, and non-irritating to pregnant women.

Ergothioneine is an imidazole alkaloid that widely exists in human blood, liver and internal organs, bacteria and plants, and has vitamin-like effects. It has been produced by synthetic method. Ergothioneine has coenzyme-like properties and participates in various biochemical activities of the human body. When applied externally to the skin, it can increase the activity of cortical cells and has anti-aging effects. Ergothioneine can inhibit the activity of melanocytes, reduce the production of melanin, and has a synergistic effect with human placenta extract. Ergothioneine has strong antioxidant properties, absorbs UV light in the D-zone, and can increase skin lightening effect.

Its role can be roughly summarized as the following points:

1. Antioxidant effect

It has the effect of antioxidants, and can also effectively remove hypochlorous acid, thereby preventing the loss of a 1-antiprotease. However, it cannot inhibit the peroxidation of lipid particles in the presence of iron ions.

2. Protective effect on cells

Ergothioneine is a powerful hypochlorous acid scavenger (HOCl), and while many compounds react with hypochlorous acid, few react as rapidly as ergothioneine. It protects red blood cells from neutrophils from either normal function or from sites of pathological inflammation.

3. Anti-inflammatory effect

Ergothioneine can inhibit peroxynitrite-mediated amino acid oxidation, such as tyrosine nitration, thus providing feasibility for the treatment of inflammation.

4. Other biological functions

It has strong antioxidant activity: scavenging reactive oxygen species, chelating divalent metal ions, activating antioxidant enzymes, inhibiting superoxide dismutase, inhibiting the oxidation of various heme proteins, etc.