#Injectable drug delivery

[healthcaremarketanalysis]

Exploring the Future of Injectable Drug Delivery Systems: Innovations and Impact on Healthcare

The field of healthcare is evolving rapidly, and one area seeing significant advancements is the injectable drug delivery system. This technology plays a crucial role in the treatment of chronic diseases, vaccinations, and emergency medical care. It allows for precise, rapid, and efficient delivery of medications directly into the bloodstream, offering several benefits over traditional methods.

What Are Injectable Drug Delivery Systems?

Injectable drug delivery systems involve the administration of drugs through needles, directly into the body’s tissues or bloodstream. These systems include intramuscular, intravenous, subcutaneous, and intradermal injections, which are selected based on the medication's purpose and the desired absorption rate. They ensure the drug reaches the bloodstream quickly, providing fast relief, especially in critical conditions.

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Benefits of Injectable Drug Delivery Systems

High Bioavailability: Since the drug is delivered directly into the body, it bypasses the digestive system, preventing any loss of efficacy and ensuring higher bioavailability.

Targeted Treatment: These systems allow for localized delivery, targeting specific areas within the body, which is particularly beneficial in cancer therapies and localized infections.

Rapid Onset of Action: Injectable drugs can provide quick relief in emergency situations, making them indispensable in cases like anaphylaxis, heart attacks, or severe infections.

Controlled Release: Innovations in injectable formulations allow for controlled release, meaning a single injection can offer therapeutic benefits over an extended period. This is particularly useful in the treatment of chronic conditions such as diabetes or arthritis.

Types of Injectable Drug Delivery Systems

Conventional Syringes and Needles: The most common method, suitable for a variety of drugs including vaccines, insulin, and antibiotics.

Prefilled Syringes: Preloaded with medication, they offer increased convenience, safety, and accuracy, reducing the risk of contamination or dosing errors.

Injectable Pens: Commonly used for insulin, injectable pens offer ease of use, portability, and precise dosing, making them ideal for long-term conditions that require regular medication.

Auto-Injectors: Designed for emergency use, auto-injectors like EpiPens administer a predetermined dose of medication and are essential in treating allergic reactions.

Needle-Free Injectors: A newer development, these systems use high-pressure technology to deliver drugs through the skin without needles, reducing pain and the risk of needle-stick injuries.

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Innovations in Injectable Drug Delivery

The injectable drug delivery system market has witnessed groundbreaking innovations aimed at improving patient experience and outcomes. Key trends include:

Biodegradable Implants: These injectables release drugs slowly over time, eliminating the need for multiple doses.

Smart Injections: Equipped with sensors and monitoring technologies, these injectables can record dosage and patient adherence, transmitting data to healthcare providers for real-time monitoring.

Microneedles: Tiny needles that minimize pain while delivering drugs more effectively, often used in vaccination efforts.

Impact on Healthcare

Injectable drug delivery systems have significantly transformed patient care by improving the efficiency and precision of treatments. They are crucial for managing chronic diseases, cancer therapies, and emergency medical interventions. Additionally, advancements in drug delivery technologies are enhancing patient compliance, offering solutions that require fewer injections, or even reducing the need for hospitalization.

Challenges and Future Outlook

While injectable drug delivery systems offer many advantages, they also face challenges such as the need for skilled administration and potential discomfort associated with needle use. However, ongoing research and technological advancements promise to address these issues. The development of needle-free injectors and automated devices is expected to make injectable therapies more patient-friendly, increasing adoption and furthering the reach of modern medicine.

In conclusion, the future of injectable drug delivery systems looks promising, with innovations making treatments more effective, accessible, and comfortable for patients worldwide. As these technologies continue to evolve, they will likely play an even greater role in improving health outcomes across various medical fields.

Content Source:

[mitalipingale]

https://biiut.com/read-blog/43192_injectable-drug-delivery-market-size-analysis-and-forecast-2031.html

The Injectable Drug Delivery Market in 2023 is US$ 45.3 billion, and is expected to reach US$ 91.06 billion by 2031 at a CAGR of 9.12%.

[reportstore]

Injectable bandages use gelling agent to stop excessive blood loss

An injectable swathe produced using a gelling specialist regularly utilized in getting ready baked goods can quit draining and advance injury mending.

Specialists from the Motivated Nanomaterials and Tissue Designing Research center, Texas, effectively made the wrap, which they accept could be utilized in the military to balance out serious combat zone wounds as it very well may be self-directed to stop over the top blood misfortune and abstain from draining.

A new article distributed in the diary Acta Biomaterialia makes sense of how Dr Akhilesh K. Gaharwar, colleague teacher in the Division of Biomedical Designing at Texas A&M College, utilized kappa-carrageenan, a typical thickening specialist, and nanosilicates to frame injectable hydrogels to quit draining and support wound mending utilizing the controlled arrival of therapeutics.

Gaharwar said: "Injectable hydrogels are promising materials for accomplishing haemostasis if there should be an occurrence of inner wounds and dying, as these biomaterials can be brought into an injury site utilizing negligibly intrusive methodologies.

"An ideal injectable swathe ought to harden after infusion in the injury region and advance a characteristic thickening outpouring. Likewise, the injectable swathe ought to start wound mending reaction in the wake of accomplishing haemostasis."

In the review, Gaharwar utilized kappa-carrageenan got from kelp to make the injectable drugs deliverable market. Hydrogels are a 3D water-enlarged polymer organization, like gelatine, which can mimic the construction of human tissues.

At the point when kappa-carrageenan is joined with mud based nanoparticles, injectable gelatine is made. The charged attributes of earth based nanoparticles give hydrogels haemostatic capacity. Plasma protein and platelets can frame blood adsorption on the gel surface and trigger mass blood coagulating.

Graduate understudy in Gahawar's lab and first writer of the new article Giriraj Lokhandea said: "Strangely, we likewise found that these injectable wraps can show a delayed arrival of therapeutics that can be utilized to mend the injury.

"The negative surface charge of nanoparticles empowered electrostatic cooperations with therapeutics accordingly bringing about the sluggish arrival of therapeutics."

For more Injectable Drug Delivery Pipeline Products Market segment insights, download a free report sample

The examination was financed by the Public Science Establishment's Substance, Bioengineering, Ecological and Transport Frameworks Division, and the Public Foundations of Wellbeing's Public Organization of Biomedical Imaging and Bioengineering.

[trans-axolotl]

US Harm Reduction Resources

continually updating, not a complete list. feel free to add on any resources you find helpful.

Free Safer Supplies:

Each organization will have different supplies, but generally, harm reduction orgs provide things like syringes, safer snorting + smoking kits, Narcan, condoms, lube, and wound care supplies. Each org has different policies for how to get supplies--some do deliveries, some have drop in centers, some only do one to one needle exchange, some are more flexible.

Next Distro: mail based syringe provider for certain states. Also mails free Narcan.

NASEN: national map of syringe providers

a lot of harm reduction collectives aren't going to have their information listed on big national websites--it's always worth searching "harm reduction in my area" and seeing what's around you. Even if you don't live in a big city, there might be a harm reduction organization in your state that can help you find someone closer to you. there's a lot of rad people doing underground work who want to be there to help you who aren't as easy to find online. If there's street medic collectives, mutual aid groups or groups like Food not Bombs in your area, you can ask people in them who might know where to find harm reduction services in your area!

Drug Users Unions:

Drug users unions are activist groups made for people who use drugs, by people who use drugs! Drug users unions do advocacy work to end criminalization, as well as providing vital community support. Many drug users unions are also inclusive of sex workers and work to decriminalize sex work as well. You can search for "drug users union" in your state.

Urban Survivors Union: National, has resources for creating drug users union

Chosen Few: Drug users union for Black drug users in DC

San Francisco Drug users union

Sex Work Advocacy Groups:

Organizations that do decrim advocacy and provide support for sex workers.

Sex Worker Outreach Project USA- National, has chapters in many states.

Black Sex Worker Collective

Sex Workers Project

How to Use Safely:

Guides, videos, toolkits for safer use!

Harm Reduction Coalition Resource Library

Getting Off Right: A Safety Manual for Injection Drug Users

Safer Crack Smoking

Safer Snorting

Safer Hormone Injection

Levels of Risk: Veins

Wound Care video w/ ASL

How to Use Fentanyl Test Strips

DanceSafe-testing kits, including reagent testing kits!

Erowid-shares experiences people have with different drugs, dosages, what things to expect

Bluelight- another forum for discussing experiences with drugs.

Drug Interactions Checker

Sex Work Resources:

Tricks of the Trade by L. Synn Stern: tips for street based sex work

A Quick and Dirty Sex Worker Safety Toolkit

Girls Do What they Have to Do To Survive by YWEP

Dis/Organizing: How We Build Collectives Beyond Institutions by Rachel Kuo & Lorelei Lee

Tryst Blog

Hotlines:

Never Use Alone: 877-696-1996. Overdose Prevention Hotline--Volunteers stay on the phone with you while you use and call emergency services if you overdose.

HIPS Hotline-​​​1 (800) 676-4477. Emotional support for drug users and sex workers. Does not work with cops.

feel free to add on more resources. love + lube <3

[reasonsforhope]

"In a first-ever human clinical trial, an mRNA cancer vaccine developed at the University of Florida successfully reprogrammed patients’ immune systems to fiercely attack glioblastoma, the most aggressive and lethal brain tumor.

The results in four adult patients mirrored those in 10 pet dog patients suffering from brain tumors whose owners approved of their participation.

The discovery represents a potential new way to recruit the immune system to fight treatment-resistant cancers using an iteration of mRNA technology and lipid nanoparticles, similar to COVID-19 vaccines, but with two key differences: use of a patient’s own tumor cells to create a personalized vaccine, and a newly engineered complex delivery mechanism within the vaccine.

“Instead of us injecting single particles, we’re injecting clusters of particles that are wrapping around each other like onions,” said senior author Elias Sayour, M.D., Ph.D., a UF Health pediatric oncologist who pioneered the new vaccine, which like other immunotherapies attempts to “educate” the immune system that a tumor is foreign.

“These clusters alert the immune system in a much more profound way than single particles would.”

Among the most impressive findings was how quickly the new method spurred a vigorous immune-system response to reject the tumor, said Sayour, principal investigator at the University’s RNA Engineering Laboratory and McKnight Brain Institute investigator who led the multi-institution research team.

“In less than 48 hours, we could see these tumors shifting from what we refer to as ‘cold’—very few immune cells, very silenced immune response—to ‘hot,’ very active immune response,” he said.

“That was very surprising given how quick this happened, and what that told us is we were able to activate the early part of the immune system very rapidly against these cancers, and that’s critical to unlock the later effects of the immune response,” he explained in a video (below).

Glioblastoma is among the most devastating diagnoses, with median survival around 15 months. Current standard of care involves surgery, radiation and some combination of chemotherapy.

The new report, published May 1 in the journal Cell, is the culmination of seven years of promising studies, starting in preclinical mouse models.

In the cohort of four patients, genetic material called RNA was extracted from each patient’s own surgically removed tumor, and then messenger RNA (mRNA)—the blueprint of what is inside every cell, including tumor cells—was amplified and wrapped in the newly designed high-tech packaging of biocompatible lipid nanoparticles, to make tumor cells “look” like a dangerous virus when reinjected into the bloodstream to prompt an immune-system response.

The vaccine was personalized to each patient with a goal of getting the most out of their unique immune system...

While too early in the trial to assess the clinical effects of the vaccine, the patients either lived disease-free longer than expected or survived longer than expected. The 10 pet dogs lived a median of 4.5 months, compared with a median survival of 30-60 days typical for dogs with the condition.

The next step, with support from the Food and Drug Administration and the CureSearch for Children’s Cancer foundation, will be an expanded Phase I clinical trial to include up to 24 adult and pediatric patients to validate the findings. Once an optimal and safe dose is confirmed, an estimated 25 children would participate in Phase 2."

-via Good News Network, May 11, 2024

-video via University of Florida Health, May 1, 2024

[im-just-a-boy-guys]

absolutely loved your minotaur breeding story <3

part two? 👀

FEM! AFAB READER ON MINOTAUR BREEDING FARM. MILKING/BREEDING/DRUGGING!

PT 2 (Any side characters unless more than once will have a purple text <)

(AS always feel free to send in writing asks and even Suggest. Things for the current stories!)

Everything is color coded. Scroll down to the main section of green text to skip to the porn! / horny stuff!

You bathed and collapsed into your bed, in your bathrobe. It had been a wild night, and you found yourself still horny and reeling from getting your guts brutally re-arranged.

You knew you needed to eat something and decided to order in some subway, praying the delivery guy would be able to make his way through the campus like set up of the farm.

You ordered your food, and after 45 minutes, thankfully, it arrived, and the doorbell to your apartment rang. You loosely tied the robe around yourself, though your large chest was still very prominent, and your cleavage shown just at the top of the relatively short robe.

You answered the door and smiled at the driver. It was a younger man, just some younger, possibly 19-year-old boy with blonde hair, brown eyes, and freckles that lightly dusted his face.

"Hello, is this (y/n)? I have a deli-", He paused, and his pale face flushed red as he saw your chest.

After today, you felt slightly turned on by the staring, and instead of covering yourself, you just smiled at him and held your hands out.

"Yes, that's me." You took the food, and he nodded, walking back down the stairs and to his car.

You brought the food inside and ate, contemplating how often you should do that just to see people's reactions outside of what you enjoy looking at you.

After you ate, you plopped back onto your mattress and fell asleep in your robe.

The next morning, you woke to an alarm you had set for every weekday on your phone and peeled yourself out of your robe. You decided that since your clothes were going to be removed anyway, you might as well wear something easy access, slipping on the bra you were given, an old tee shirt, and a pare of short shorts that hugged your thighs.

You wet and brushed your hair, doing your hair care and lathering yourself in your 'Whisky and Coffee' lotion.

You hoped that if you smelled better that they might pick it up with their sensitive noses. You'd love to be made fun of for seemingly wanting it more - wanting to drive them crazy.

After the lotion, you tossed your hair up into a ponytail, pulling a couple of strands out in the front.

Once you grabbed your things, you left your apartment to see a woman dressed in uniform waiting in a golf cart.

"Hello (Y/N), I'll be your driver! There and back. The Dr will still be the one giving you your injection if you end up needing it. But for the drives, it'll be me.", The slender, darker-skinned woman smiled brightly at you. She looked like she'd been kissed by the sun, and her hair coiled so beautifully. Once she saw you up close, she couldn't help but smile. You sat next to her in the golf cart and said quietly.

"You're very beautiful."

She blushed all the way up to her ears and laughed softly. "Oh you don't mean that. I could never be as beautiful as all of the women here- they and you are so amazing looking.", she scoffed and then seemed to realize she'd included you individually.

You smiled at this endearingly, and she sputtered.

"I'm sorry- was that to foward- I'm new to this and don't want to make you uncomfortable. "

You giggled and placed your hand reassuringly on her thigh,

"Nono, it's ok. I know what you meant. And thank you. I think you could actually do this if you wanted. If there were any spaces available, of course. Daniel? I think I'd like the managers name. He seems super sweet and understanding. Maybe speak to him about it if you think about it."

She looked taken aback by the suggestion but nodded politely. You really didn't want to overstep but hoped she'd take it as a compliment. She was however, too busy thinking about being suffocated by your breasts and thighs to really have been offended.

"I think I'd like to stay your driver. You seem nice!"

She pulled up next to the stables and stopped the golf cart.

"Alright, ma'am! Here we are! I'll see you when you get off work."

You smiled and gave her a soft kiss on the cheek before hopping out of the cart and making your way into the stable. On your way in, you see Dr Sylvia in your stall waiting for you. She looks you up and down.

"Do you need help getting undressed?" You thought about it and couldn't help but want her hands on you.

"Please." You smiled and lifted your arms for her to help you out of your shirt, and she lifted it off for you, setting the discarded clothing on a stool to the side. She helped unclip your bra and helped you shimmy out of your shorts.

She couldn't help but gawk at your thong. You smiled proudly but did your best to hide it as she slipped them off of you.

"Alright, for now I'm just going to run a couple of general physical tests to make sure you're fit to work today."

She gently took one of your breasts into her hands and massaged it roughly.

"Does this hurt any?"

She kept a straight face but was clearly enjoying groping you. You shook your head, trying to keep a dumb look off your face. She swapped breasts and squeezed once more.

"What about this one?"

You shook your head again and kept up your smile. It took everything not to beg her to keep touching you. You'd love it if she put you in that machine and had her way with you.

"Good. Do you want your shot today or no?"

Your face flushed. "I think I'd like it every time - you can refrain from asking next time-" you mumbled lightly.

"I kind of liked not knowing I was being drugged-",

She smiled mockingly and raised an eyebrow.

"Not a problem. Whatever makes the experience more enjoyable for you, sweetheart."

Your soul melted at the probably frequently used nickname. You knew she more than likely called all of her patients various nick names and treats them the same way, but some part of you daydreamed that your body was her favorite.

She gently guided you and strapped you down by the wrists and ankles as you straddled the adjustable bench. She elevated the back. Putting you at a slight incline before injecting the serum.

She walked in front of you, holding your face for a moment as she stood there. The woman made you look up at her and smiled down at you almost mockingly.

The way her red hair sat in her messy bun drove you insane. She was so gorgeous, and the way her eyes showed when she looked at you like you were nothing - ugh.

She slipped her thumb over your lips before slipping out of the stall.

"Have fun, doll."

Your pussy ached, and you couldn't help but let out a soft whine as the drugs started to take effect.

A familiar buzzing sounded, and you heard the metal doors creak open. You were waiting on the sound of praise from your beloved bulls from yesterday but were met with two entirely different voices. One rumbling lowly, almost scarily close to a gruff growl.

"She seems new- she's super fucking hot though. What do you think about this one, Jake?"

A large figure passed you, seemingly larger than even the bulls you'd met yesterday and a heavy blush covered your face as you were met face-to-face with his giant cock. You drooled almost instantly.

"Her tits are huge - he looks like she'll be lots of fun."

They looked at you like meat, and you were so into it. The drugs made your head feel hot and swimming thoughts as your head flooded with all of the things they might do to you.

The one who was apparently named Jake pulled a leaver under your head, and the headrest folded back, causing your head to fall limp back over it. He pressed his tip to your mouth and smiled.

"Start sucking."

You didn't know how you felt about his tone, but it seemed to make you even wetter. You opened your mouth and stuck your tongue out. He smirked down at you and grabbed your throat, then without warning or prep, shoved himself down your throat.

"God- damn it that's so good-",

The other followed suit by pressing his tip to your needy hole, he teased himself by tip fucking you for a few minutes, every time you felt you were getting close, he'd pull out.

After a few times of that, he shoved his full length into you, pressing himself against your cervix.

He pressed down on your lower stomach/ bladder while he moved inside of you, just to see the imprint of his length through you.

you moaned as they began to move faster, slamming their hips into you, Jake groaned as your moans vibrated your throat against his cock.

"Fuck~ just like that-", Jake groaned and huffed,

the other bull moaned out, "I wanna fuck her ass, it looks even tighter than her pussy-"

You blushed as your mind swam. You'd never done anal before and heard it was quite painful, but all you could think about was the two creatures using you.

"You know- we might be able to break the cuffs and have some fun. We'll just clamp them back after. What do you say, Liam?"

"I say what are we waitting for?," The smaller bull smirked and gripped the ankle cuffs, prying them open one at a time with a great deal of effort, being the cuffs were assumedly made to prevent this exact scenario.

Jake did the same to the arm cuffs. You tried to get up, to struggle, to move, anything. You found that you couldn't move. You'd never noticed before because you were tied down and couldn't move anyway, but now you could feel the active numbness in your skin.

"Awe, I think she's trying to get away~" Liam cooed at you as Jake took you into his arms. He wrapped your legs around him, holding you up far enough to drop you down onto his throbbing cock, you moaned out and he kept one arm around your waist and shoved one of his huge fingers into your mouth.

Liam walked up behind you and held your ass up, gently pressing his tip against your ass hole, he probed for a moment, pushing in just enough to open you up.

Your body felt so limp that you could feel your own weight, pulling you down against their lengths. you couldn't hold your head up, so you rested against Luke's chest.

you felt a sharp pain and cried out weakly as the smaller bull forced himself into you, his warm chest against your back. You could feel his breath in your ear, his grunting causing your pussy to leak cum down your thighs.

His cock seemed to rub in all the right places and you couldn't help but drool. As the drugs reached their full effect, you felt like you couldn't possibly take it or be more full, you thought they were going to rip you in half from both ends, and you were hungry for it.

Once you were filled by both of them, they both held onto your hips and helped each other pump into you. They moaned and cursed into your ears.

They occasionally praised you, fondly licking at your cheeks as they used you. Luke leaned down and put your neck roughly, just barely keeping himself from drawing blood.

"Careful Jake- I'm going to fucking kill you if we lose another week's worth of privileges-", Liam spat at the other as he thrusted into you.

You could feel their knots pressing against your holes, begging for entry. They were both in your guts, their cocks rubbing against eachother through the thin layer of skin between your entrances.

You managed to muster a quiet sentence, almost not heard over your money and whimpers.

"Please cum in me~", you begged them,

"You hear that? The pretty cow wants our cum- how bout we fill her up and swap. We should spend all of our time wisely."

He chuckled mockingly into your ear as they both made an effort to thrust faster, occasionally lifting you higher to tease their tips.

"Fuck- fuck I'm so close- take my knot bitch-"

This caused your pussy to clench roughly around the bigger bulls cock as you squirted, covering his stomach and strong thighs.

As you came, your asshole checked around Liams length, he moaned lewdly before thrusting his knot violently into you, spewing his cum into your virgin hole.

His cum was so hot and thick, you could almost feel it in your stomach, you didn't think you could be any more full.

Until Jake pushed his knot unto your dropling cunt, you screamed as their knots rubbed together inside of you, milking themselves. Their grunts were enough to make you cum again as if their knots didn't.

He jammed his head against your cervix, using that to further milk himself as your guts rubbed his sensitive tip just right.

His cum seemed to be even warmer, it was so think and filled you so well that it leaked down over his cock and down your thighs.

They panted softly, and Jake lifted you off of them, allowing Liam to lay down on the bench you had been clamped down to.

The bigger bull gently layed you onto of the other, your tits resting softly against his face. Liam groped them roughly, causing milk to sport out softly against his face. He snickered,

"Oh yeah, I forgot that we were breeding a milk cow - she's one of the special ones."

Liam took both of your sensitive nipples into his mouth and sucked aggressively, groaning happily as your milk filled his mouth.

You could feel his head prodding at your entrance and leaning back against it, helping him enter you.

Jake came up behind you and thrusted into your now comfortably stretched hole, still rubbing against all of your sensitive spots. As he moved, Liam began to pump gently into you.

He moved casually, just enjoying the sensation of you as he drank your milk, and you only squirmed lightly as he groped and massaged your breasts.

"I think the drugs are wearing off. But she's behaving so well- think we should pick up the pace for her? She's doing so good and looks like she could really use our loads-"

Jake smirked as his hands slipped to your hips, his big hands gripping them roughly.

The smaller bull nodded half-heartedlyas he teased your nipples with his tongue and began to move faster into you, their cocks once again rubbing against eachother with only your thin walls to separate them.

Your tongue hung out of your mouth like a desperate dog and you could still feel their cum on your thighs and leaking out of you like a creame filled donut.

You whimpered and whined as they moved, and the feeling of Liams tongue on your nipples sent a signal to your sloppy cynt that you couldn't describe, a pulsing in your clit-

You reached down between your legs and rubbed desperately, the sensations driving you insane.

The smaller bull let go of your breasts and grabbed your hands roughly. He held them together over his shoulder, which caused you to elongate yourself, your back arching further against Jake.

He took happily to this, smiling dazedly as your ass pressed against his length, causing him to go even deeper.

Without the extra cum in you you imagined he'd split you in half, you almost wanted another dose of the drugs, you imagined the warm dazed feeling flooding your head like the few times you'd had to many drinks.

"Fuck I love how she sounds- she makes so many cute noises when she's getting her guts peniteated."

Liam cooed this into your ear, and he grabbed your throat. This was almost better than the drugs, the static flooded from your neck where his strong hand gripped, moving up to your already foggy brain.

Your vision flooded in and out as he let go right before you felt like you were going to pass out. You could feel their cocks throbbing against your walls, and their knots had grown back to their full size, slamming against your entrances.

Liam huffed and used both hands to use your throat as his leverage, pounding mercilessly into you.

You squeezed in excitement as you felt yourself getting close to your own climax once more.

Jake chuckled and pushed the back of your head into Liams chest. Your tongue still hung out of your mouth, Liam mocked,

"I think our milk cow might be part mutt-", He looked down at you and gripped your throat as tight as he could with both hands before pushing his knot as hard as he could unto you, Jake following suit.

Their cum flooded your guts and at the same time, you whimpered and whined loudly, screaming out as you squirted against Jake's thighs, the cum running down your own thighs onto Liams legs.

They both rested inside of you as their cum spewed against your walls, once again bursting out of you and around their cocks.

When they pulled out, another stream of cum sprayed on your back and stomach. They panted and gently lifted you and placed you back onto the chair face down, clamping the cuffs back around your limbs.

They both came around to your face and licked at your cheeks softly.

"We had a lot of fun, pretty cow. Hope we get to see you again."

Jake winked and walked away to the back door of the stall.

"Hopefully, well, see you later, Mutt."

Liam granted you a small head scratch before walking away with the other.

Soon after, Dr Sylvia walked into your pen and to your little bench. She examined the bars and groaned.

"I swear - these two do this every time. Did they take you out of your restraints?"

You nodded softly and tried to speak and managed to weakly,

"Yes, but I had fun.."

She shook her head softly and pressed the button to unclasped your cuffs.

"Yes, but what if they do this to someone who doesn't? It also just generally isn't safe for the cuffs to be all bent uo like this. Don't you worry though, sweetie. I'll get this all sorted out. Now let's see if we can get some of that milk out of you, huh?"

Her velvety voice slipped through your ears, and you smiled, pressing your chest out slightly, hoping to make it easier for her as she lowered the breast holding arm.

"Thank you, darling."

She cooed and gently attached the pumps to your nipples. A decent amount of milk still cane out, but only half of the container was filled compared to last time.

She clicked her tongue.

"And they took most of your milk - unbelievable. Next time, I'll give you double the dose."

She shook her head and smiled at you, kissed your forehead, and helped you get off of the table.

She helped you into your robe and handed you your clothes, and carried the milk pump to the golf cart. Sylvia offered your arm to assist you as you stepped into the seat, and your assigned driver looked over at you and blushed.

You looked an absolute mess and she couldn't help but stair as the cum that coated the top of your cleavage.

"See you tomorrow!"

The Dr waved goodbye to you and smiled.

Your driver kept quiet most of the ride, which seemed to be nice considering the shift you'd had.

Once she pulled up to your apparent, she helped you up the stairs and into your apartment.

"You haven't set up your bed yet?"

You shook your head and fell onto your mattress. She pouted softly and pulled out her phone.

"I'm going to have the staff come and help you set up. It's not too late, so I'm going to have them come help. Do you have a couch?"

You nodded lightly and gestured to the living room.

"Come on then. You can lay there until they help you with the bed. Where's your bedding?"

You pointed at the closet,

"it's in a clear bag, the one it came in."

She nodded and helped you to your couch, which was drowning in boxes in your living room. She stepped to the side once you'd laid down and made a couple of calls. You could barely make out what she was saying before you fell into a light sleep.

You woke up to the woman gently shaking you awake. Most of the boxes were moved out of the way to make a path to the different rooms and open up some floor space. She helped you to your room, and you saw your bed frame set up and your bedding laid out.

This made you smile, and you thanked her. You walked into your bathroom, and your driver saw herself out, locking the door from the inside before closing it.

You bathed and slipped happily into your soft sheets and cozy, fluffy duvet; dreaming about your wonderful night.

[jymwahuwu]

Summary: You have been kidnapped and sold as a pet. Blade wants a pet. Content Warning: kidnapping, non-con, dehumanization, body modification (just nipples ><), lactation, humiliation, yandere

dark content, minors DNI

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Looking for a promise of love? Searching through 3,000 planets, but can't find the one you dreamed of? Everyone else says they can't provide the pet you want? Want that she/he/them/it in your life?

Space Pet Home Company has more than 5,000 pet breeds, providing you with a variety of choices. Buy now and get a free pet care and medical checkup! No matter what galaxy you place your order in, our couriers guarantee delivery to your door.

For details, please visit the official website and social media news. The precious opportunity to meet with pets is right in front of you!

＊(According to the newly revised "Interstellar Pet Act", the company can make a little body modification without compromising the life rights and health of pets.)

-

Last week a man who lived down the street was taken and disappeared. People are talking about it. It was the employees of the Space Pet Home Company who caught him. Those disrespectful aliens roam the galaxies, capturing random species to sell. This is contemptible. Still, there's nothing anyone can do about it. Under the gaze of a powerful space civilization, the planet you live in is trampled like ants.

On the way home, you browsed the news with your mobile phone, and found that some people searched for the man's photo and selling price on the official website, and posted it on the discussion forum. They offer to raise funds to buy him back to the planet. This is already the most likely way to redeem them to their original planet. You clicked on a link to the pet company's website. Ironically, that's a cute design with clouds and a rainbow, and a little animation that brings the pet home. The website loaded for a while, and a picture of the man was displayed. He looked at the camera with a calm expression on his face. You have no idea what they did to him.

Name: ▄▆▄▂▅▅▄▃

Price: 200000

Below is a description of the pet. You read a few words and feel so sick and horrified. There is also "More Recommendations", which introduces pets of different species, from cats, tentacles, humans to supernatural creatures.

You close the page and want to donate some money. However, you feel a cold, prickly sensation in the back of your neck.

Half a second later, as if stepping on air in the sky, you plummet.

-

Blade was more irritable than ever. This time, the target of the mission made a provocation, leaving some traces, deliberately mocking them. He then "solved" them, a little rougher than usual. The problem is, for the next three days, he was just as "rough". He even declined Silver Wolf's invitation to play a racing game together. Silver Wolf remained expressionless, indicating that she didn't care, but the atmosphere became a little depressed.

"Bladie, did you know? Elio said you're getting a pet this month."

"I don't need a pet." No doubt, that's stupid.

Kafka's eyes narrow, and smiles. She said in a certain, seductive tone. "Are you sure? Imagine getting that little kiss after a mission…kneeling down to relieve you…"

"No," he snapped, getting up and walking into the darkness.

-

"Currently scanning for physical condition-"

"Number E92730012 is in good condition. Everything is fine."

"Suggestion: Transform the nipples into a breast-feeding state, and add drugs to enhance sensitivity."

You are in a coma, two robotic arms grab your hand and stretch out, and two needles are aimed at your nipples on both sides to inject medicine. Some subtle changes are transforming your boobs.

"Hmm…" Your head shook slightly, but your eyelids were so heavy that you couldn't open them, and you could only bear the sensitivity and a little pain on your chest. The machine continued to inject the medicine without mercy, and gradually, some white milk flowed out from the flower buds, dripping on the ground, exuding a sweet smell.

-

Not this… and not this.

None of them fit.

If the other Stellaron Hunters saw Blade now, they'd think he was nostalgic about something and wouldn't bother. No one knew he was looking at the official website of Space Pet House. He has searched with keywords, but the results are still not what he wants.

He decided to go to the store in person.

-

It's been three days, maybe… five days?

You can't believe that you've been captured and sold as a pet. The store was decorated like some kind of spider web, some kind of hideous lair. Placed across from you are about thirty transparent cages of various species, including six humans. Some people try to resist like you, slapping the cage and cursing at the clerk, only to get some accusing looks from them, like they are really looking at a naughty pet. Some had given up and stayed quietly in the cage, looking at the guests curiously.

Your neck is covered with a black lace choker and a heart bell. Clean water, food and toys are placed in the cage. You can't believe it and don't want to play with those toys for cats.

When those guests visit, they always whisper which pet is better and more suitable. Among all the customers, you are impressed by a certain man. His dark blue fringe draped over his forehead, and his waist was covered with long hair. His hair dangles along with certain bandages as he walks around the store. He's… charming, in every sense of the word, but creepy, with those red eyes that wander from cage to cage and finally stare at the cage you're in. This situation lasts for tens of minutes, scanning your information and prices.

You don't know if he wants to buy you, because when the clerk asks if he needs to go further and allow him to play with you for a while, he just walks away.

-

"It's been seven days… still no one wants to buy this pet. Why…"

"Maybe we can help."

-

"No…don't! Please! Please, I'll be good!"

You plead as you struggle. The clerk still pulls down your sheer clothes, exposing your breasts and locking your hands above your head. The tears in your eyes are swirling, whimpering, thick milk flowing down the swollen breasts.

The door bell rang and two guests came in. They looked around the store. When they caught a glimpse of you, their eyes visibly lit up and they walked in your direction.

"Today's special offer, milk production anytime...?" One of the guests read out the information under your cage in a low voice - that's the first time you know what's written there. The way they look at your naked breasts seems to be on fire in you. "sounds good."

"Didn't know you were interested in that." Another guest snickered.

"Such a beautiful little thing can change my mind. I hope this time the pet will not be destroyed so quickly…"

You shudder at the implications of his words - this is a lunatic who isn't taking care of pets. what should you do? What if you were bought by this person? You may be facing a more dire situation than you are now…

There is a raging and dangerous atmosphere wandering in the store. You see that familiar face from behind the two customers. He stood behind them, but didn't seem to see them at all. He feels his crotch tighten when he notices your breasts dripping with milk.

-

He licks away any sweet milk that pervades your swollen buds, sweet, rich, and creamy. His hand is rubbing your other breast and pinching your nipple. It doesn't take much force, the milk is already squirting. Your bewildered moan turns into a scream as your lower body bounces, the fluid squirting against his cock.

In the orgasm, you stick out your tongue, address him unconsciously, and touch his palm. It's cold.

"Blade." He said his name.

“…?”

You touch his chest, where the heart is beating and echoing. A warm feeling sinks in.

[cassieoz]

Transition

Amber looked desperately into the nurse's eyes as the next brutal contraction slammed into her laboring core.

"Thats it, Amber! The pains are getting harder and harder. You need to focus and stop fighting the urge to birth! Pushing will help you now!"

Amber glared at the nurse, clutching her hand and wailed out in total agony. The severity of the birthing surges were unbearable. The eruption of pain ignited Amber's entire nether region. The enormous crown pressed downwards as the delivery doctor worked at the end of the birthing bed.

Amber panted frantically as the beeping of the monitors elevated her anxiety. The tension in her contracting body only caused her more discomfort. She was overwhelming frightened about how painful this birthing ordeal had become.

Suddenly, the delivery doctor looked up and ordered the nurse to administer more of the new birthing formula.

The nurse filled the syringe and passed it rapidly to the delivery doctor. She clutched Amber's hand as the injection was administered. Instantly, Amber's eyes rolled back and she screamed at the top of her lungs. The pain doubled and the need to push was immediate.

The birthing mother bore down on the humongous crowning tip. The sphere stretched her folds outwards. The delivery doctor watched the monitors and the birthing head. It was excruciating but it was finally starting to birth. The new formula was extremely effective. The babies were getting bigger but the drug was assisting in delivering them successfully.

Amber sobbed as the requirement to birth became unstoppable. Her cries of birthing echoed wildly for the next hour. All she could was bear down, harder and harder, longer and longer until the head was in the final stage before delivery.

She was exhausted! Amber shook weakly as the delivery doctor announced that it was almost over! The birthing patient looked up the nurse and whispered,

"Oh, its finally ending. The pain! The pressure! Too much......oh here it comes......can't stop it.....must push......NOW......I NEED IT OUT!"

[mitalipingale]

https://twikkers.nl/blogs/217370/Injectable-Drug-Delivery-Market-Size-Analysis-and-Forecast-2031

The Injectable Drug Delivery Market in 2023 is US$ 45.3 billion, and is expected to reach US$ 91.06 billion by 2031 at a CAGR of 9.12%.

[mindblowingscience]

Materials engineers at Stanford University have developed a novel hydrogel drug delivery system that transforms daily or weekly injections of diabetes and weight control drugs like Ozempic, Mounjaro, Trulicity, Victoza, and others to just once every four months. In a new study, published Nov. 21 in Cell Reports Medicine, researchers believe that such a system will greatly improve management of both diabetes and weight, improve patient drug compliance, and help those with Type 2 diabetes improve long-term health outcomes. These drugs all work by mimicking the hormone glucagon-like peptide 1 (GLP-1). But, as good as they are at helping people manage their diets and their weight, the typical daily or weekly injections are a burden for many patients. “Adherence is one of the biggest challenges in Type 2 diabetes management,” said Eric Appel, associate professor of materials science and engineering at Stanford and principal investigator on the new hydrogel that allows the slow release of the diet control drugs over many months. “Needing only three shots a year would make it much easier for people with diabetes or obesity to stick with their drug regimens.”

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