#Human Insulin Online

[healthlineonline]

Buy Humulin R Insulin to Control Metabolism and Glucose

The Humulin R USA is a peptide created with the help of beta cells in the pancreatic Islets embedded in humans by the insulin gene. In other words, when the pancreas does not produce enough insulin or when the body has a high amount of insulin, this medicine is taken to regulate the levels. Diabetic patients often buy Humulin R USA, a fast-acting insulin that helps manage blood sugar levels in people with diabetes. Humulin R, produced by Lilly Turkey, is human insulin that mimics the body's natural insulin production. For more details click:

https://genxxlgear.com/peptides-hgh-2126/humulin-r-53175.html

[copperbadge]

Watching Twitter implode, as an outsider who has hated Twitter for an extremely long time, is absolutely fascinating. I had a twitter account, now deleted, which I checked about once a month and posted to every few years, usually in a vain attempt to acclimate myself to a system I felt was hostile to any method of communication I was capable of. For about a year now even checking my notifications has been pointless, since I was quoted in a tweet by some corporate account that the spambots got hold of; literally all I saw in my notifications for a very long time was ads for various things attached to my name, retweeting that fucking train quote.  

I understand the importance of twitter particularly in uplifting marginalized voices and chronicling major historical events in first-person witness accounts; I know people personally whose small businesses are absolutely fucked because they depended on twitter for almost all their PR and a vast portion of their sales, and that truly sucks. It’s easy to glibly say “and nothing of value was lost” but a lot of value is being lost. 

But I also just hated everything about trying to use twitter. I can understand its importance and still hate it. I also don’t like the Mountain Goats even though they are vitally important to the emotional stability of like, half the people I know. 

The upshot of this is that I eventually had only a dim understanding of the way twitter culture evolved, since I wouldn’t go near it with protective gear on. So I was absolutely dumbfounded to read articles about the Verification badge being put up for sale and to see people saying, “Well, if Twitter’s no longer trustworthy, why be there?”

It blew my mind to realize that in introducing verification in the first place, Twitter had given its entire userbase explicit permission to abandon critical thought when they saw that alluring blue bird. Because twitter verified people, it seems a huge number of users thought they didn’t need to question anything on the site and, because of the way most social media works, the site also quickly became a series of personal filter bubbles. 

It makes the last few years make sense, in a weird way -- it’s not just that a massive chunk of culture abandoned critical thought, it’s that they were told that was okay to do, every day, every time their eyes hit the site. And Twitter is structured to offer diminishing returns on a hard dopamine hit, so a lot of people were on it a lot. I’m not throwing stones -- I’m physiologically constantly a quart low on dopamine, so I’m on Tumblr for much the same reason. And I’m not saying that anyone who is Chronically On Twitter has no critical thinking skills. But I am saying that it appears the vast majority of people who let their online critical thinking skills go slack did so because Twitter said it was okay. Twitter said, we’ll do the questioning for you. 

(Watching Twitter implode as someone familiar with the psychology of D/s relationships is....also fascinating.) 

The coverage of the Lilly tweet in particular is interesting in relation to this because it doesn’t seem like anyone is asking who made the tweet. Perhaps there’s no way to find out, but I don’t even see threats or attempts. Eli Lilly is suing Twitter and doesn’t seem even inclined to ask about the human who did it; nobody at Twitter, to my knowledge, has vowed to find and punish the perpetrator, which is hilarious given what Musk clearly wants to do to the people mocking him personally. No major media outlets seem interested in reporting on people discussing the question, let alone asking the question themselves, which indicates to me that nobody’s gone looking. If people are asking, they are not asking loudly or visibly. 

And don’t get me wrong, I don’t want us to find the person who tanked Eli Lilly stocks en route to reopening the discussion about price-gouging in the healthcare field. I wish there was a way to buy them a beer and/or a vial of insulin. But the fact that nobody seems to even be asking the question is weird -- until you remember it’s twitter, and nobody asks questions when it comes to twitter. Why would you? Twitter does the asking. 

And absolutely vitally -- where the fuck is Donald Trump? 

(Questions you never think you’ll ask.) 

Elon Musk promised to reinstate him; even if you claim staffing issues, he’s managed to kill all advertising on the site and switch off two-factor authentication, but he couldn’t flip the switch on Trump’s twitter account? Or personally offer him a new one under the aegis of the freest of speeches? Less than a day ago Trump was still trying to get the courts to give him his bluebird back. I don’t want him back on twitter, lord knows, but I’m perplexed that he’s not, because that was part of the package deal Musk was pitching. 

It’s almost like Musk knows what the bridge too far is. And nobody is asking about that either.

I hope people who come here from twitter find joy here. I hope the ship of twitter is righted so that my friends who love it can go back to it, so that the artists and writers I know can get back a vital tool for their creative self-support and the activists I know can regain a great tool for effective organizing. Twitter is a huge part of the cultural landscape and I hope it ends up okay, and I hope the staff still there can get some rest. 

But I also hope that this sharp cultural shock has been a reminder that letting someone else ask the questions means letting someone else control what answers you get.

[chocxy-prince]

if my mental illness doesn’t kill or get to me first, these heart issues will, or the feds because of me making jokes about trump dying from his wounds.

[Just so we’re clear, i’m a minor who’s freaky publicly sometimes, and i also have a partial trigger finger. let me know if i post something triggering but i wont take it down unless somebody asks me to, okay? all i ask is that you block me and move on if you don’t like it.]

(Also consists of several resources for different things. if you want me to add something, let me know! Also these aren’t mine! All links go to original posters.)

Ask Game (s):

https://www.tumblr.com/miss-mossball/174904972404/artist-ask-meme?source=share

Palestine/General Scam Account List:

Palestine Campaigns with Under a 1000 Donations:

Vetted Palestine Campaigns (1):

General Palestine Resources

Cookie Run Kingdom Anatomy Guide:

STOP KOSA Resources: An Internet bill going through Congress that can limit safe spaces online and forums to talk about international issues, including Sudan and the Palestine Genocide.

Helmet PSA:

Firearm Drawing Info:

[hyperactivetransdrone]

Blog Intro

So after looking through several peoples profiles I noticed that introductory posts were pretty common (at least for nsfw sooo here we gooooo)

I'm adding this later on 8/18/24: If (majority) your content is s**sy and your DMing me to try to dominate me, Don't. While I don't mind people who do that/are into that being called that feels like a sexualization of my identity and ergo 1: I hate 2: is disgusting to me, I don't mind if you Identify as one or if you DO just wanna CASUALLY chat but please know that I won't and will never want that or say that word (with the exception of blocking tags involving it or here as a boundary) but if i need to it will be censored. I don't mind if you Identify as one and wanna follow me or anything or just wanna casually chat (or talk sexual just not... making me one to try to explain) feel free to I will NEVER kink shame regardless of how I feel so this won't apply to most people just a very very teeny tiny minority. I won't block you tho unless you cross a boundary or keep pushing, because I feel anyone who wants to read my content should be allowed.

I would also like to say, if you're going to delete your account please don't dm me, it breaks my heart every time

Hello I do not wish to give out my actual name online so you may call me Mz. Hyde (I stole it from the song by the same name by Halestorm) or just... my user-name-tag-thing (always forget what its called)

Outside of this post any posts in blue is rping as a slime-girl-queen-goddess-character. Feel free to send asks or responses directed at her. Her title is Queen of Slimes, The Slime Goddess, or The Slime of the Lake

As of posting this I am still brand new to Tumblr but am learning somewhat quickly sooo things may look A Little odd right now to the average Tumblr user but as soon as I finish learning the basics it should look fine.

Anyway:

18 so 18+ only please, (pre-hrt) Transfem, Bisexual, Autisic+ADHD, overall anxious/shy-ish, probably a switch, Lefty, Type 1 Diabetic (I require insulin to survive), Virgin [:(]

Majority of this blog will be kinky thoughts usually about being dommed or hypno because... I wanna try it. SOME is fantasy tho so keep that in mind (usually my reblogs)

If you are a dom looking for money, unless you are popular and have a good community on here or if you are a s**sy tamer (or whatever it would be called) please don't DM me, unless you just wanna casually chat and don't wanna dom me or if you do please respect:

I really don't like being called an s**sy and will give you one warning before I block you.

I literally have no way to pay you so please don't expect that.

Please read this first, or if I ask you to because otherwise that gives me a red flag in my head and I will probably block you. (Unless it's just casual talking but that's different than what I'm talking about here)

My proof that I take this seriously:

Kinks because that seems to be an important factor on making these types of posts/blogs: Transformation, Hypnosis, Dronification, Denial/Edging, Latex, Brainwashing, Bimbofication, Twinning, Dollification, Forniphilia, Exhibition

Things I enjoy but aren't kinks: Forced Fem, Praise, Good Girl (I'll add more when I think of them)

Limits or things that I will block you about: Human Waste, Blood, Physical Harm, IRL Identity Death (Fantasy is hot AF tho), Sissy (WILL BLOCK YOU), Findom (Unless we're in a romantic relationship), (and a few more I can't remember off the top of my head)

The reason for physical harm being a limit is mostly due to personal problems I've had with S.H. and because of that I hate reading S.H. or other stories or fantasies with physical harm or knifes. Fantasy Violence is ok though. (E.G. Pirates or like a battle between two warrior framed in a Fictional light.) Oh and also no needles. BIG fear of needles, for multiple reasons. Will go in depth if asked.

Finally a few final things about me/general questions:

This is my first Tumblr account that is SPECIFICALLY for NSFW things although I will occasionally post more SFW things but I do love music, video games, card/board games, RPGs/TTRPGs, creative writing, art.

What's your Favorite Color?: I don't have one but my fav combo is Hot Pink and Deep Purple, pretty much if you've ever seen those BIC octagonal see-through pens, those shades of pink and purple specifically

What kinda music do you like?: Power Metal, Rock, some Pop

What video games do you play?: Some Pokemon, Batman: Arkham, Smash Ultimate, Fallout, I can't really get online games yet so unfortunately I cannot play with anyone :'(

Is there anything specific you like about your kinks?: Honestly, in a vacuum I like dronification for productivity because I SUCK at doing anything productive.

The people who have sent questions about Gaza Support (i am broke but here are links to them i am just going to put their profiles for the sake of simplicity and nc some links i cant copy paste):

@ehabayyad23

@freepaleatine95

@mahmoudayyad

@esraayyad14

@ezzaldeens-blog

@foggyruinspost

@ahmed4palestine

@sspsworld

@fidaa-family2

@wafaaresh6

@mahmoudswierh2

@generousvioonanuttieyl

@nishverian

@ahmedalnabeeh11

@shinytastemakerphantom

Tags to find non-reposts easier (Umm i ran out of colors so these will be bold):

#Random Thoughts, #Edging kink (for post horny thoughts), #Hornyposting (for horny thoughts), #Hydes eepy thoughts (for thoughts i have when sleep deprived), #Hydes Ideas (cool ideas i have), #Hydes Hypno Scripts (for Hypnotic Scripts I make), #Hydes QnA (QnA), #Hydes Depressed Thoughts (Thoughts I have when depressed), #Hydes Kinky Thoughts (thoughts I have that are just generally kinky but it's not hornyposting nor... I forgot what I was going to put here), #Hydes Hypno Scripts (My hypnosis scripts), #Slimeposting (Slime Queen RP posts)

If I get any FAQ I'll either add them here or to a FAQ post.

I now have a sideblog for latex things that look perfect. That is an opinion and just a kink the person they are under the latex is, in my opinion, someone different so anything there that I call 'perfect' is just in terms of kinkiness NOT a reflection of the actual person. The blog is: @trans2latexperfection

If you read this far thank you for reading!!! :3

Blocked Users (i dont normally block people so these people are scammers or assholes, also will not be using @ s either here):

mistress-elizabethh - for calling me a s**sy twice, even after claiming to read pinned

[voesneroeiz]

The continuous bombardment and the ongoing genocide pose a significant threat to their well-being. What pains me even more is that due to the lack of medications in Gaza, my Mom, who is a type 2 Diabetis patiant and was scheduled for an urgent eye surgery, have had no access to insulin or any medical care for the past 3 months. Some of my family members sought refuge in the southernmost part of Gaza (Rafah) in tents. However, my parents, and sisters have no alternative place to stay, forced to remain in the Nusierat refugee camp, which is now the subject of continuous severe bombardment since christmas started.” Am on my knees requesting for your donations. Please help where possible.

you copy and pasted your entire post from an actual person’s gofundme. you couldn’t even be bothered to post the majority of it.

this could be forgiven if you were the actual person behind it, but you’re not. all it took was a google search of the name on your paypal for me to find out who you are and what city you lived in. (or i’m assuming it’s you— not a lot of guys online with your name.) i won’t put your personal business on blast just in case it’s not you but i’ll gladly send a screenshot of your paypal info since you posted it first.

you are an actual waste of human life for trying to use a genocide for your own financial gain, noah. please kill yourself at your earliest convenience.

[lazyyogi]

Matcha Health Science: An Evidence-Based Review

Recently I found a fantastic tea company called Tezumi that obtains teas from all over the world, namely Japan. I got to talking with the owner and he invited me to write a post for their blog about the scientific publications that have been done regarding matcha's health benefits. I thought you all would enjoy it too! Link.

A gurgling, clear stream from a boiling kettle tumbles into a vessel holding dried plant matter. A frenetic symphony of swirling H2O molecules draws out a host of larger, more complex molecules: catechins, epicatechin, gallocatechin, L-theanine, caffeine, and more. The steaming water, now steeped with a plant’s essence, is strained into a clean empty cup. For thousands of years this was the universal chemical process for the creation of tea. It is called infusion. 

Black tea, oolong tea, white tea, and green tea are all brewed via an infusion process. However, there is a curious exception within the world of tea: matcha. While all other teas are extracts infused into warm water, matcha is a suspension. The powdered green tea is suspended, floating within the water, and then whisked into a thick solution with a light foamy topping. 

How did this unique beverage come to be? 

The story goes that a particularly brutal Japanese winter hundreds of years ago inspired farmers to cover their tea plants with straw to shield them from the damaging frost. The plants, in response to the shade created by this covering, synthesized more chlorophyll to maintain energy metabolism. The farmers then discovered that these new, darkly pigmented plants made for an even more robust and rich brew of green tea.

When a traveling monk named Eisai returned to Japan after traveling in China, he supposedly introduced a powdered suspension method for tea brewing. Combining one tea innovation with another, the result is supposedly the matcha we know today. 

While there are various health benefits attributed to all kinds of teas, matcha enjoys a superior status because it is a suspension rather than an infusion. A simple online search yields a bevy of claims from preventing disease to curing cancer. But what does our most rigorous, evidence-based scientific research tell us about the true benefits of matcha?

Obesity and Metabolic Syndrome Benefits

Studies in both mice and humans have given evidence for several benefits matcha may provide regarding obesity and appropriate weight loss. 

A Chinese study by Wang Et al.1 created an experiment in which they divided mice into four groups. Two groups were given either a high-fat or normal diet while another two groups were given matcha supplementation along with either a high-fat or normal diet. A number of different variables were then analyzed before and after the 8-week experiment, including blood lipid levels, blood glucose levels, liver enzymes, fat and liver cell samples viewed under a microscope, gut microbiota, fecal bile acids, and more. 

When comparing the high fat diet with the high fat plus matcha diet, the study found that matcha supplementation inhibited the fat accumulation and limited the dyslipidemia and hyperglycemia caused by the high fat diet. Additionally, matcha reshaped the intestinal microbiome by promoting bacterial strains associated with healthy body weight, reducing glucose and increasing insulin levels, and reducing inflammation. There have been other well-designed studies with similar findings in humans as well.2,3

Put simply, there have been repeated experiments with findings that suggest matcha intake may benefit prevention and reversal of obesity as well as the serologic, microbiotic, and histologic markers associated with metabolic syndrome. And for those who may not be aware, metabolic syndrome significantly increases risk for heart attack, stroke, and diabetes. 

Cognitive and Systemic benefits

A South Korean study examined the effect of matcha on cognitive dysfunction and systemic inflammation in mice.4 The authors stated, “Air pollution is a complex mixture of particulate matter that contains heavy metals, carbon monoxide, sulfur dioxide, polycyclic aromatic hydrocarbons, and ozone, and is known to be harmful to human health.” They further explain that the pollution “is absorbed through a variety of pathways, such as skin, nasal cavity, respiratory organs, and digestive system, and causes type 2 diabetes, respiratory infections, cardiovascular disease, and systemic inflammation.” This in turn also creates oxidative stress in the brain, leading to cognitive impairment. 

Few studies have examined the way matcha may impact individuals exposed to pollution, especially with respect to the effects on cognition. The authors set out to answer these questions by designing a sophisticated experiment with mice. Essentially, they were exposed to high levels of pollution and one group received matcha extract while the other did not. 

The results were extensive. To summarize: matcha inhibited cognitive dysfunction caused by the neurotoxic effects of pollution, downregulated systemic inflammation, reduced behavioral and memory dysfunction, promoted lung, skin, and brain anti-oxidation, improved regulation of mitochondrial function, and benefited several cholinergic and anticholinergic systems.

Several other studies in humans have found similarly encouraging results with respect to the impact of matcha on overall brain health.5 Some have even found results that suggest green tea may reduce the risk for developing Alzheimer’s and other forms of dementia.6

A systematic review7 of matcha’s health benefits created the following diagram to summarize:

Takeaways

Whether improving cognitive performance, protecting important organ systems, or reducing the likelihood of developing metabolic syndrome, matcha has effects on the human body that are as complex as its own storied history. The ongoing study of this traditional beverage will continue to shine light on its potential benefits. 

While the evidence does suggest that matcha may benefit several conditions, there can be too much of a good thing. Drinking matcha in excess can lead to nausea, vomiting, acid reflux, and may worsen symptoms for anyone with stomach ulcers. Furthermore, there is no evidence to suggest that matcha may treat health conditions in the absence of our current medical standards of care. 

My advice? A cup or two of matcha tea per day is a reliable lifestyle addition for experiencing the relaxed focus effect of combination caffeine and L-theanine. And in doing so, you can enjoy the added satisfaction of knowing you are likely benefiting your brain, metabolism, and intestinal microbiome.

Citations

Wang Y, Yu Y, Ding L, Xu P, Zhou J. Matcha green tea targets the gut-liver axis to alleviate obesity and metabolic disorders induced by a high-fat diet. Front Nutr. 2022 Aug 1;9:931060. doi: 10.3389/fnut.2022.931060. PMID: 35978960; PMCID: PMC9376390.

Paradee Auvichayapat, Montira Prapochanung, Oratai Tunkamnerdthai, Bung-orn Sripanidkulchai, Narong Auvichayapat, Bandit Thinkhamrop, Soontorn Kunhasura, Srisuda Wongpratoom, Supat Sinawat, Pranithi Hongprapas, Effectiveness of green tea on weight reduction in obese Thais: A randomized, controlled trial, Physiology & Behavior, Volume 93, Issue 3, 2008, Pages 486-491, ISSN 0031-9384

El-Elimat T, Qasem WM, Al-Sawalha NA, AbuAlSamen MM, Munaiem RT, Al-Qiam R, Al Sharie AH. A Prospective Non-Randomized Open-Label Comparative Study of The Effects of Matcha Tea on Overweight and Obese Individuals: A Pilot Observational Study. Plant Foods Hum Nutr. 2022 Sep;77(3):447-454. doi: 10.1007/s11130-022-00998-9. Epub 2022 Aug 3. PMID: 35921023; PMCID: PMC9362463.

Kim JM, Kang JY, Park SK, Moon JH, Kim MJ, Lee HL, Jeong HR, Kim JC, Heo HJ. Powdered Green Tea (Matcha) Attenuates the Cognitive Dysfunction via the Regulation of Systemic Inflammation in Chronic PM2.5-Exposed BALB/c Mice. Antioxidants (Basel). 2021 Nov 30;10(12):1932. doi: 10.3390/antiox10121932. PMID: 34943034; PMCID: PMC8750520.

Anas Sohail A, Ortiz F, Varghese T, Fabara SP, Batth AS, Sandesara DP, Sabir A, Khurana M, Datta S, Patel UK. The Cognitive-Enhancing Outcomes of Caffeine and L-theanine: A Systematic Review. Cureus. 2021 Dec 30;13(12):e20828. doi: 10.7759/cureus.20828. PMID: 35111479; PMCID: PMC8794723.

Kakutani S, Watanabe H, Murayama N. Green Tea Intake and Risks for Dementia, Alzheimer's Disease, Mild Cognitive Impairment, and Cognitive Impairment: A Systematic Review. Nutrients. 2019 May 24;11(5):1165. doi: 10.3390/nu11051165. PMID: 31137655; PMCID: PMC6567241.

Kochman J, Jakubczyk K, Antoniewicz J, Mruk H, Janda K. Health Benefits and Chemical Composition of Matcha Green Tea: A Review. Molecules. 2020 Dec 27;26(1):85. doi: 10.3390/molecules26010085. PMID: 33375458; PMCID: PMC7796401.

[roxylexie01]

The continuous bombardment and the ongoing genocide pose a significant threat to their well-being. What pains me even more is that due to the lack of medications in Gaza, my Mom, who is a type 2 Diabetis patiant and was scheduled for an urgent eye surgery, have had no access to insulin or any medical care for the past 3 months. Some of my family members sought refuge in the southernmost part of Gaza (Rafah) in tents. However, my parents, and sisters have no alternative place to stay, forced to remain in the Nusierat refugee camp, which is now the subject of continuous severe bombardment since christmas started.” Am on my knees requesting for your donations. Please help where possible.

I hope this can reach many people. I always try to reblog everything I find that can be of help in this inhumane situation. I'm unfortunately not as knowledgeable as others here or on Twitter for donations/helping aid online sites. Therefore I'll leave links to other useful posts I found on here.

For anyone who's able to help by donating I'll leave this one, but you can help even if you're not able to donate so go read it, it's extremely important!

Here is another one with also a link to donate directly to UNRWA.

[aroseofonesown]

On the impossibility of being feminine

Possible trigger warnings for body dysmorphia Like many a way-too-online Millennial, I enjoy some Instagram scrolling. I like seeing other similar mid-size women being fashionable and being healthy. Recently I had to unfollow most of these accounts because I was finding they were triggering body dysmorphia in me to a dangerous level. To be very clear I was not following young, thin, super hot fashion and gym girlies. I was following pudgy women in their 30s and 40s who jog, or lift weights, or wear sexy dresses. Women I identified with and/or was inspired by. What I found was that so much of their content was them responding to the horrific comments they were being left every day. Just them posting and responding to those comments was sending me into horrible anxiety spirals. I am not policing these women. They should not have to take that shit silently. I think they are way stronger than me for being able to keep posting despite the harassment they get, and I know a lot of women enjoy mocking the trash that post those kinds of comments. For me though, seeing these comments drove home to me the impossibility of being feminine. What follows is the crystallization of my interpretation of this behavior and why I think it happens. This is in no way an academic analysis but is based solely on how I feel about what is going on. I believe that feminine bodies are judged in 3 categories by our patriarchal and predatory culture. In all three of these categories, the female body is an object, because as Simone de Beauvoir famously stated, “Man is defined as a human being and woman is defined as a female."

I want to be clear, this 3 object mindset exists because of our patriarchal society but it not perpetuated only by men, and it hurts so many more people than just women. The 3 objects feminine bodies are categorized into into are: 1) Sexual objects: Feminine bodies that are seen as sexually desirable are given privileges above all other women in our society but are very often subjected to unwanted advances, comments, and sexual violence. The sexual object's role is to be pretty, and complaint. If not compliant her compliance will be enforced with violence. 2) The invisible object: Femine bodies that are not seen as traditionally sexually desirable, make no effort to be so and present as sexless. They do not challenge the culture categorization but instead, accept it. They blend into the crowd and tend not to be subjected to verbal or physical violence because of their appearance. 2) Sexually repulsive object: Femine bodies that are not seen as traditionally sexually desirable, but refuse to be invisible. That does not mean they won't be sexualized, far from it. Many fetishized feminine bodies fall into this category. Fat women who declare they are sexy/healthy, trans women just existing, sexually "promiscuous women", and minority and disabled women all often find themselves in this category. The sexually repulsive object is often pushed into this "repulsive" category because she will not or can not mold herself into a pleasing "sexual object" and refuses to become an "invisible object" People who fall into this category frequently experience intense harassment and are subjected to very violent enforcement to push them in the other two categories. It was an existential mind fuck to really understand how my choices came down to being "invisible" or being "repulsive". I am almost 40, have a kid, have very intense insulin-resistant PCOS. I will never be traditionally sexy. I am ok with that. What guts me though, is that I love fashion. I want to be dressed head to toe in standout outfits. I want gloves, and hats, and big ball gown skirts. I want my existence to be loud. If I choose that I will be subjected to violence in an attempt to make me invisible. Deep Breath This is a universal experience for feminine bodies. If we choose to be our authentic selves, we make ourselves targets. I wish I could say I am just going to get angry and be stunning anyway. I honestly don't know right now how loud I will allow myself to be, but I also know it is deeply important for me to understand why I am scared of embracing my authentic self. Why I found it so existentially threatening to watch women who looked like me be insulted for doing pushups or wearing a tight dress. I want to embrace my femininity, but I also don't want to be yelled at and called horrible things and fear for my safety. I also know that as an only mildly disabled cis middle-class white woman, I don't have it nearly as bad as many others. Is it important allyship to stand up against this vitriol? Sure, but am I emotionally strong enough to do it? I don't have an answer yet, but I hope by writing this out it helps me find my way. ETA: not everyone thinks this way of course but this is just my personal theory about why some people get so much more harassment than others.

[warningsine]

Scientists at Johns Hopkins Medicine say that an experimental monoclonal antibody drug called mAb43 appears to prevent and reverse the onset of clinical type 1 diabetes in mice, and in some cases, to lengthen the animals' lifespan.

The drug is unique, according to the researchers, because it targets insulin-making beta cells in the pancreas directly and is designed to shield those cells from attacks by the body's own immune system cells. The drug's specificity for such cells may enable long-term use in humans with few side effects, say the researchers. Monoclonal antibodies are made by cloning, or making identical replicas of, an animal (including human) cell line.

The findings, reported online and in the May issue of Diabetes, raise the possibility of a new drug for type 1 diabetes, an autoimmune condition that affects about 2 million American children and adults and has no cure or means of prevention.

Unlike type 2 diabetes, in which the pancreas makes too little insulin, in type 1 diabetes, the pancreas makes no insulin because the immune system attacks the pancreatic cells that make it.

The lack of insulin interferes with the body's ability to regulate blood sugar levels.

"People with type 1 diabetes face lifelong injections of insulin and many complications, including stroke and eyesight problems if the condition is not managed properly," says Dax Fu, Ph.D., associate professor of physiology at the Johns Hopkins University School of Medicine and leader of the research team.

Fu says mAb43 binds to a small protein on the surface of beta cells, which dwell in clusters called islets. The drug was designed to provide a kind of shield or cloak to hide beta cells from immune system cells that attack them as "invaders." The researchers used a mouse version of the monoclonal antibody, and will need to develop a humanized version for studies in people.

For the current study, the researchers gave 64 non-obese mice bred to develop type 1 diabetes a weekly dose of mAb43 via intravenous injection when they were 10 weeks old. After 35 weeks, all mice were non-diabetic. One of the mice developed diabetes for a period of time, but it recovered at 35 weeks, and that mouse had early signs of diabetes before the antibody was administered.

In five of the same type of diabetes-prone mice, the researchers held off giving weekly mAb43 doses until they were 14 weeks old, and then continued dosages and monitoring for up to 75 weeks. One of the five in the group developed diabetes, but no adverse events were found, say the researchers.

In the experiments in which mAb43 was given early on, the mice lived for the duration of the monitoring period of 75 weeks, compared with the control group of mice that did not receive the drug and lived about 18–40 weeks.

Next, the researchers, including postdoctoral fellows Devi Kasinathan and Zheng Guo, looked more closely at the mice that received mAb43 and used a biological marker called Ki67 to see if beta cells were multiplying in the pancreas. They said, after treatment with the antibody, immune cells retreated from beta cells, reducing the amount of inflammation in the area. In addition, beta cells slowly began reproducing.

"mAb43 in combination with insulin therapy may have the potential to gradually reduce insulin use while beta cells regenerate, ultimately eliminating the need to use insulin supplementation for glycemic control," says Kasinathan.

The research team found that mAb43 specifically bound to beta cells, which make up about 1% or 2% of pancreas cells.

Another monoclonal antibody drug, teplizumab, was approved by the U.S. Food and Drug Administration in 2022. Teplizumab binds to T cells, making them less harmful to insulin-producing beta cells. The drug has been shown to delay the onset of clinical (stage 3) type 1 diabetes by about two years, giving young children who get the disease time to mature and learn to manage lifelong insulin injections and dietary restrictions.

"It's possible that mAb43 could be used for longer than teplizumab and delay diabetes onset for a much longer time, potentially for as long as it's administered," says Fu.

"In an ongoing effort, we aim to develop a humanized version of the antibody and conduct clinical trials to test its ability to prevent type 1 diabetes, and to learn whether it has any off-target side effects," says Guo.

Other scientists who contributed to the research include Dylan Sarver, G. William Wong and Maria Golson from Johns Hopkins; Shumei Yun from the University of Maryland, Aaron Michels and Liping Yu from the University of Colorado; and Chandan Sona and Matthew Poy from Johns Hopkins All Children's Hospital.

[thenightsystem]

hi!  I am desperately in need for help.

#Type1Diabetes , I'm a dead human 😭. I'm a disabled mom so can't work after I had an accident. I've a spinal cord problem ..my blood sugar is high and I'm last to my pen.

I urgently need $ 350 for insulin.

ANY donation would be hugely appreciated.

There isn’t much we can do for you, due to being a minor with no way to send money online, but I will post it incase someone who can help sees it. I’m sorry, I hope you get the money you need.

-host

[mariacallous]

After Elon Musk rolled out a confusing and ever-evolving new verification system on Twitter this week, parody accounts posing as large corporations spread confusion on the site. The most prominent was a fake account for the pharmaceutical giant Eli Lilly, which announced that insulin would now be free to customers. Soon the official Lilly account stepped in to refute the news, issuing a statement that apologized for the misunderstanding but avoided, of course, apologizing for how expensive insulin is in the first place. Lilly’s hasty apology is the latest in what Jill Lepore identifies in this week’s issue as a required—and often deeply unsatisfying—ritual of corporate communications in the social-media age. Everyone knows that companies sometimes have to say sorry, but do they ever mean it? And does it really make a difference if they do? “The practice of establishing and enforcing strict requirements for public apology is not a human universal,” Lepore writes. “It happens only here and there, and now and again. You see it in fiercely sectarian times and places—like twenty-first-century social media, or seventeenth-century New England.” You think it’s bad now? Just imagine the Puritans on Twitter.

Whose P.R.-purposed apology was worse? Al Franken’s or Louis C.K.’s? The Equifax C.E.O.’s (for a cybersecurity breach) or Papa John’s (for a racial slur)? Awkwafina’s (for cultural appropriation) or Lena Dunham’s (for Lord knows what)? At SorryWatch.com and @SorryWatch, Susan McCarthy and Marjorie Ingall have been judging the adequacy of apologies and welcoming “suggestions for shaming” since 2012. “There are a lot of awful apologies out there,” the SorryWatchers write. “Apologies that make things worse, not better. Apologies that miss the point. Apologies that are really self-defense dressed up as an apology. Apologies that add insult to injury. Apologies that are worse than the original offense. Apologies so bad people should apologize for them.” McCarthy and Ingall are releasing a new book next year, “Sorry, Sorry, Sorry: The Case for Good Apologies.” Meanwhile, on their Web site they’ve got rules—“Six steps to a good apology”—and categories for classifying defective ones: “Be VEEERY CAAAREFUL if you want to provide explanation; don’t let it shade into excuse.” Heaven forfend.

“Least said, soonest mended” is advice from another century, candle and quill, ox and cart. This past March, the day after Will Smith smacked Chris Rock at the Oscars and failed to apologize to him during his acceptance speech, he apologized on his Instagram account: “I was out of line and I was wrong.” Twitter blew its top! “This is bullshit,” one guy tweeted. “Any normal person is in jail.” Plainly, the Instapology was insufficient. In July, Smith apologized again, in a nearly six-minute video in which he looked as harried and trapped as Steve Carell in “The Patient,” a prisoner in a basement rec room. “Disappointing people is my central trauma,” Smith said into the camera or, actually, multiple cameras. “I am trying to be remorseful without being ashamed of myself, right?” Twitter blew its top! It was either not enough or, oh, my God, please stop. One online viewer sympathized: “Literally me when my mom forces me to apologize to my siblings.” As for Chris Rock, he reportedly said, onstage, “Fuck your hostage video.” By then, Twitter was blowing its top about something else.

It’s easy to blow your top, God knows. If you’re being treated like crap, and nothing you’ve tried has put a stop to it, or if the former President of the United States keeps on saying horrible, wretched things, and you notice that some rich nitwit is getting slammed on Twitter for doing the same thing that’s been done to you, or for saying what the ex-President just said, it can feel good to watch that nitwit burn. But that feeling won’t last. And when that nitwit apologizes it won’t be enough. And the world will have become just a little bit rottener.

Rating apologies and listing their shortcomings started out as a BuzzFeed kind of thing, and then it pretty quickly became a corporate kind of thing: human resources, leadership institutes, political consulting. In 2013, the Harvard Business Review published an essay on the Power Apology. Knowing how to apologize on Twitter became crucial to brand management. “It’s easy to say sorry, but knowing how to say it effectively on Twitter is an essential skill that both brands and celebrities should learn,” a communications manager advised not long afterward, offering nine lessons “on the art of the Twitter apology.” You could do it well, or you could do it badly. Likely, this could be quantified: you’d see it in the price of your stock, the number of your Twitter followers, or the percentage change in your Netflix viewership. As of 2022, even Forbes rates apologies. It seldom helps your vote count, though: politicians who apologize tend to suffer the consequences, which is why they generally brazen these things out.

It’s a good idea to say you’re sorry when you screw up, and to say it well, and to mean it, and to try to make amends. But are people getting worse at that? Or are celebrity publicists, political advisers, corporate lawyers, higher-ed administrators, and media-relations departments just avoiding lawsuits, clearing profits, heading off student protests, and directing news stories by advising people to (a) demand apologies and (b) make them? “Examples of failed apologies are everywhere,” the psychiatrist Aaron Lazare wrote in “On Apology,” a book published not last week but nearly two decades ago. Distressed at a seeming explosion of cheap, showy, and insincere apologies, Lazare got curious about where they’d all come from, like the day you find ants swarming your kitchen counter and yank open all the cupboards, exasperated. He dated what he called the “apology phenomenon” to the nineteen-nineties, but he struggled to understand what had driven this change. He suspected that it may have been due, in part, to “the increasing power and influence of women in society,” because women apologize a lot, he explained, and like to be apologized to. As far as I know, no one asked him to apologize for that comment. But if he’d made it today he’d be in the soup.

Rituals of atonement and forgiveness lie at the heart of most religions, a testament to the human capacity for grace. On Yom Kippur, the Day of Atonement, Jews fast and pray and repent. Jesus brought this spirit to Christianity and taught his followers to pray to God to “forgive us our trespasses, as we forgive those who trespass against us.” The early Christian church developed what became the Sacrament of Reconciliation: confession, and penance. There are many steps to atonement in Islam, from admitting a wrong to making restitution and asking for God’s forgiveness. Jews, Christians, and Muslims make themselves right with God. Buddhists, who worship no god, make themselves right with other people. Hindus practice Prayaschitta, rituals of absolution. Mainly, it’s the forgiveness and the atonement that matter.

Apology, though, has a different history. You can confess without apologizing and you can apologize without confessing, and this might be because, historically, an apology is a justification—a defense, not a confession. As the philosopher Nick Smith pointed out in “I Was Wrong” (2008), the word “apology,” in English, didn’t suggest a statement of regret until around the sixteenth century, when, in Shakespeare’s “Richard III,” Buckingham begs Richard’s pardon, for interrupting his prayers, and Richard says, “There needs no such apology.” Medieval Christians practiced what the historian Thomas N. Tentler called “a theology of consolation,” consisting of four elements—sorrow, confession, penitence, and absolution—whose purpose was reconciliation with God and with the body of the faithful. In “Forgiveness: An Alternative Account,” Matthew Ichihashi Potts, a professor of Christian morals at Harvard Divinity School, offers what he calls “a modest theological defense of forgiveness.” His argument follows that of the philosopher Martha Nussbaum, who, in “Anger and Forgiveness” (2016), argued that forgiveness isn’t salutary for either party if, in order to give it, you insist on an apology. Potts calls this “the economy of apology.” It’s not better than vengeance, since to demand an apology and to delight in the offender’s grovelling is vengeance by another name. His evidence doesn’t come from Twitter; it comes mainly from novels, including Marilynne Robinson’s “Gilead” and Toni Morrison’s “Beloved.” Forgiveness, for Potts, is not an exchange—forgiveness granted in return for the opportunity to witness a spectacle of abasement and self-loathing—but a promise not to retaliate. Demanding an apology in exchange for forgiveness can never constitute healing, or deliver justice; it is, instead, a pleasure taken by people who delight in witnessing the suffering of those in their power (if only briefly). There is no such thing as a failed apology, then, only an abuse of power, because all forgiveness, Potts writes, “begins and ends in failure”: it does not, and cannot, redeem or undo pain and loss; it can only demand the necessary attention to pain and loss, as a reckoning, as an act of grief. Forgiveness is, therefore, a species of mourning, a form of sorrow.

Within the early Christian West, acts of public supplication—begging pardon—required confession and might require restitution, but not the scripted public apology in the sense the SorryWatchers want. The same distinction can be made within the history of Judaism. In the twelfth century, the Spanish-born Rabbi Moshe ben Maimon, known as Maimonides, wrote a commentary on the Torah and the Talmud that included a section on teshuvah, or “repentance,” an extended reflection on the commandment that “the sinner should repent of his sin before God and confess.” But, as the Jewish historian Henry Abramson remarked in a recent study, “The Ways of Repentance,” Maimonides warned against public confession that “can also be an expression of personal arrogance: ‘Look how good I am at doing teshuvah! ’ ” Watch my apology video on YouTube!

In “On Repentance and Repair: Making Amends in an Unapologetic World,” the rabbi Danya Ruttenberg translates Maimonides into a step-by-step guide for our world, for which she provides modern-day examples. The first step is “naming and owning harm” (one of her examples: “I finally understand how my decision to hold a writer’s retreat at a plantation sanitizes the horrors of slavery”); the second is “starting to change.” Step three: restitution. Step four: apology. Step five: making different choices. These are kindhearted ideas, and Ruttenberg’s book is full of hope and counsel about repair through restitution. But her prescriptions also come close to insisting on the suppression of dissent. She says that “starting to change,” for Maimonides, might have involved “tearful supplication,” but that “these days this process of change might also involve therapy, or rehab, or educating oneself rigorously on an issue about which one had been ignorant or held toxic opinions.”

“This book started on Twitter,” Ruttenberg writes, which is something of a tip-off. “Twitter gamifies communication,” the philosopher C. Thi Nguyen has argued; it’s custom-built to do things like score apologies, to drag users into a rating system that has nothing to do with morality. An unforgiving god rules Twitter, where the modern economy of apology runs something like this: If you express what I believe to be a toxic or ignorant opinion, you must apologize according to my rules for apology. If you do, I may forgive you. If you don’t, I will punish you, and damn you unto eternity.

The practice of establishing and enforcing strict requirements for public apology is not a human universal. It happens only here and there, and now and again. You see it in fiercely sectarian times and places—like twenty-first-century social media, or seventeenth-century New England.

Consider a case from October, 1665, when the Massachusetts legislature assembled in Boston to attend to a docket of ordinary affairs, a day in the life of a puritanical theocracy. It set the price of grain: wheat, five shillings a bushel; barley, four shillings sixpence; corn, three shillings. It addressed a petition filed by three Native men, including the Pennacook sachem Wanalancet, regarding an Englishman’s claim to an island on the Merrimack River. It warned one unhappy, estranged couple, Mr. and Mrs. William Tilley, that he must “provide for hir as his wife, & that shee submit hirselfe to him as she ought,” or else he would be fined and she would be imprisoned. In honor of God’s having graced the colony with abundant rain during the summer and mercifully diverted a fleet of Dutch ships from an invasion, the legislature appointed November 8th “to be kept in solemn thanksgiving,” but, because a plague was still raging in London, a sign of God’s wrath, it declared November 22nd “a solem day of humilliation.” And it condemned five men who had dared to practice a heretical religion, Baptism, at which announcement one colonist, Zeckaryah Roads, blurted out “that the Court had not to doe wth matters of religion.” He was detained as a result.

For the things they said—words whispered, grumbles muttered, prayers offered, curses shouted—dissenters, blasphemers, and nonconformists in seventeenth-century New England faced censure, arrest, flogging, the pillory, disenfranchisement, exile, and even execution. Quakers might have their ears cut off. For holding toxic opinions, one blasphemer was sentenced to have the letter B “cutt out of ridd cloth & sowed to her vper garment on her right arme.” Those who wished to avoid or mitigate these consequences might apologize in public. Mostly, apologies followed a script. The Six Steps to a Good Apology! Disappointing People Is My Central Trauma: How to Avoid the Eight Worst Apologies of 1665! Earlier that year, just months before Zeckaryah Roads dared to voice dissent, Major William Hathorne, of Salem—an ancestor of Nathaniel Hawthorne’s—issued a public apology for his own (now lost to history) error: “I freely confesse, that I spake many words rashly, foolishly, & unadvisedly, of wch I am ashamed, & repent me of them, & desire all that tooke offence to forgive me.” That did the trick. You went off script at your peril, as the historian Jane Kamensky demonstrated in her masterly book “Governing the Tongue” (1997). In the sixteen-forties, observers deemed Ann Hibbins’s apology—essentially, for being abrasive, and a woman—“very Leane, & thin, & poore, & sparinge.” It saved her neck, but not for long: in 1656, Hibbins was hanged to death as a witch. Still, there was one other option: after John Farnham refused to apologize for countenancing heresy, and was therefore banished, he said the day he was kicked out of the church “was the best day that ever dawned upon him.” I mean, fuck it, there was always Rhode Island.

Lately, online, you can find modern apologies ranked by the same standards once so punctiliously applied by Puritan divines. “I doe now in the presence of god & this reverand assemblage freely acknowledg my evell,” Henry Sewall confessed in a church near Ipswich in 1651, although, as he pointed out, he’d been forced to make that apology “as part of ye sentence” he’d been given by the Ipswich court. He squeaked by with that one, but just barely. Modern SorryWatchers might rate it Garrison Keillorian.

In 1665, for intimating that the government ought not to banish people for being Baptists, or kill them for being Quakers, Zeckaryah Roads did what he had to do, as chronicled in the meeting records, “acknowledging his fault, & declaring he was sorry he had given them any offence, &c.” Easy to say from here, of course, but I wish to hell he hadn’t.

The twenty-first-century culture of public apology has its origins in the best of intentions and the noblest of actions: people seeking collective justice without violence for terrible, unimaginable acts of brutality, monstrous wickedness, crimes against humanity itself. In the aftermath of the Second World War, churches and nation-states began issuing apologies for wartime atrocities and historical injustices. Some of the abiding principles that lie behind this postwar wave of collective apologies also found expression in “restorative justice”—individuals making amends to their victims, sometimes as an alternative to incarceration or other kinds of force and violence. The idea gained influence in the nineteen-seventies, when it intersected with the victims-rights movement, and its particular demands for apology as remedy. And you can easily see why. Prosecutors—for years, decades, centuries—had failed to act on allegations of sexual misconduct, had ignored or suppressed evidence of police brutality and predatory policing; in a thousand ways, the criminal-justice system had failed women and children, had failed the poor and people of color. For some, “restorative justice” held out the prospect of a better path. By the nineteen-nineties, schools and juvenile-justice systems had begun using restorative-justice methods, often requiring, of public-school students, public apologies. Meanwhile, in the United States, church membership was falling from around seventy-five per cent in 1945 to less than fifty per cent by 2020. In many quarters, public acts began taking the place of religious ritual, political ideologies replacing religious faith. The national public apology took on the gravity and solemnity of a secular sacrament: Ronald Reagan apologizing, in 1988, for the imprisonment of more than a hundred thousand Japanese Americans during the Second World War (and providing limited reparations); David Cameron apologizing, in 2010, for Bloody Sunday; or the Prime Ministers of Canada apologizing, in 2008 and 2017, for the practice of taking Indigenous children from their homes and confining them to schools where, maltreated, neglected, and abused, they suffered and died.

Apology came to play a role, too, in therapy, including family therapy, in twelve-step recovery programs, and in H.R. dispute-resolution procedures. Conventions that were established for heads of states and churches making public apologies to entire peoples against whom they had committed atrocities came to be applied to apologies from one individual to another, for everything from violent crime to petty insult. The person became the collective. Eve Ensler’s 2019 book, “The Apology,” in which she imagines the apology her father never offered for sexually abusing her, is dedicated to “every woman still waiting for an apology.” The particular injury became the universal harm. “We all cause harm,” Danya Ruttenberg writes in her book on repentance. “We have all been harmed.”

But the origins of the Twitter apology orgy lie elsewhere, too, and especially in the idea that many kinds of speech can be harm, a conviction central to the brand of feminism founded in the nineteen-nineties by the legal theorist Catharine MacKinnon. (Her book “Only Words” was published in 1993.) In 2004, in “On Apology,” Aaron Lazare tried to figure out when the number of public apologies began to explode. He counted and identified a rise in the number of newspaper articles about apologizing, beginning his analysis in the early nineteen-nineties and identifying a peak in 1997-98. He found this puzzling. But, historically, it makes sense: his chronology nicely lines up with Anita Hill’s testimony at the Clarence Thomas hearings, in 1991, and with the breaking of the Monica Lewinsky scandal, in 1998. Thomas maintained his innocence, and although Clinton went on television later that year and admitted to the relationship, many viewers found his apology inadequate. And neither man seemed sorry, either, except insofar as they both quite plainly felt very, very sorry for themselves.

The refusal of Thomas and Clinton to apologize for the ways in which they had harmed women took place on television. And the whole spectacle, with its scripted expectation of apology and contrition, drew its sensibility from television. In the nineteen-eighties and nineties, the stock soap-opera plotline—betrayal, hurt feelings, and misunderstanding followed by tearful apology, reconciliation, and reunion—became a hallmark of the daytime talk-show circuit. Oprah and Phil Donahue staged churchy apologies in front of studio audiences, choreographed for maximum emotional intensity, and advancing the idea that every possible political, economic, or social injustice, from child abuse to police brutality and employment discrimination, could be addressed by a two-shot, a few closeups, and Kleenex. Donahue mounted an especially perverse sorrywatching spectacle in 1993. The year before, after a jury acquitted four Los Angeles policemen who beat Rodney King and riots broke out in angry, anguished protest, a group of Black men pulled Reginald O. Denny, a white man, out of his truck and beat him nearly to death. Henry Keith Watson, charged with attempted murder, was found not guilty, and was convicted only of misdemeanor assault. After Watson got out of jail, Donahue brought Denny and Watson together in front of an almost entirely white audience for a two-part apology special. “Are you sorry?” Donahue asked Watson, again and again, as the audience grew tense and even tenser. “I apologize for my participation in the injuries you suffered,” Watson said to Denny. Then Watson eyed the audience: “Is everybody happy now?” Everybody was not.

Demanding public apologies on daytime television and deeming those apologies insufficient was an occasional thumb-wrestling match between two seven-year-olds sitting on a green vinyl school-bus seat on the ride to second grade compared with the daily, Roman Colosseum-style slaughtering that takes place online. It’s not that people don’t do and say terrible things for which they ought to atone. They do. Some of those things are crimes. Many are slights. Very many are utterly trivial. A few are almost unspeakably evil. But, on Twitter at its worst, all harm is equal, all apologies are spectacles, and hardly anyone is ever forgiven.

In 2017, at the height of the #MeToo movement, Matt Damon tried to rate harm. “You know, there’s a difference between, you know, patting someone on the butt and rape or child molestation, right?” he said in an interview on ABC News. “They shouldn’t be conflated, right?” At that, Minnie Driver tweeted her ire, and later told the Guardian, “How about: it’s all fucking wrong and it’s all bad, and until you start seeing it under one umbrella it’s not your job to compartmentalise or judge what is worse and what is not.” Damon apologized, and said that he’d learned to “close my mouth.”

In 1993, Phil Donahue seemed to think that, by asking Henry Keith Watson to apologize to Reginald Denny in that studio, he was bravely addressing the problem of racism in America. Twenty years from now, what’s been happening on Twitter will likely look exactly as grotesque and cruel and ineffective as that two-part, syndicated apology special. Will Donald Trump or anyone in his inner circle ever apologize for anything—for tearing toddlers from their parents’ arms, for inciting neo-Nazis, for grift, fraud, sedition? Never. Will responding to the gaffe of the day by demanding a six-step apology usher in an age of justice for all, or an end to iniquity? No. There’s a reason Puritanism did not prevail in America; it tends to backfire. In 2018, during an exchange on Twitter, the television writer Dan Harmon apologized for sexually harassing the writer Megan Ganz, and then made a heartfelt video, elaborating. “We’re living in a good time right now, because we’re not going to get away with it anymore,” he said, referring to sexual misconduct. And I hope that’s true. But very little evidence suggests that calling people out on Twitter, self-righteous indignation followed by cynical apology, is making the world a better place, and much suggests that the opposite is true, that Twitter’s pious mercilessness is generating nothing so much as a new and bitter remorselessness.

“I don’t give a fuck, ’cause Twitter’s not a real place,” Dave Chappelle said last fall, in his Netflix special “The Closer.” In June, on the Amazon Prime series “The Boys,” a made-for-television Captain America-style superhero named Homelander, who is secretly a villain, recited a rehearsed apology on television, only to unsay it later, in an unscripted outburst. “I’m not some weak-kneed fucking crybaby that goes around fucking apologizing all the time,” he said, seething. “I’m done. I am done apologizing.” Around the time the episode appeared, the actor who plays Homelander, Antony Starr, who was found guilty of assault and released on probation, told the Times, unabjectly, “You mess up. You own it. You learn from it.” No “I am listening,” no “I am going to rehab.” None of it. It was as if he got away with going off-script because his character already had. And Homelander won’t be the last to make that “I’m done” speech. “I’m done saying I’m sorry,” Alex Jones yelled in a courtroom in September during a trial to assess the money he’ll be required to pay the parents of very young children who were killed in a mass shooting, a shooting that Jones has for years insisted never happened, because those children, he told his audience, never existed. Jones has been found liable for defamation. Even the hundreds of millions of dollars in damages he was ordered to pay to the families whose despair he worsened, and on whose affliction he feasted, goes nowhere near far enough. And neither does any apology.

Twitter is blowing its top, some very angry people very loudly demanding apologies while other very angry people demand the denunciation of the people who are demanding apologies. Dangerously, but predictably, the split seems to have become partisan, as if to apologize were progressive, to forget conservative. The fracture widens and hardens—fanatic, schismatic, idiotic. But another way of thinking about what a culture of forced, performed remorse has wrought is not, or not only, that it has elevated wrath and loathing but that it has demeaned sorrow, grief, and consolation. No apology can cover that crime, nor mend that loss. ♦

[ithappensblog]

nice to meet you

Hi, I’m Jenny and welcome to my blog. In this post, I want to share with you some of the highlights and challenges of my life so far, and how I’m trying to find my purpose and happiness in this world.

I’m almost 34 years old and still struggling to figure out my life. Aren't we all? I’ve gone to school for a diploma program in Medical Laboratory Technician/Phlebotomy, a diploma program for Accounting Technician, and started my Human Resource Management diploma program too. I’ve always wanted to be an RN but, life and my body had other plans for me. I’ve always been interested in learning new things and pursuing different careers, and I've finally found one which fulfills me. I have a really good job now, but I’m not really supposed to talk about what I do so I’m going to leave that part out, but it’s finally something I’m good at and something I enjoy doing. It pays well and gives me flexibility and stability. It also challenges me and allows me to use my skills and creativity.

I have a husband who I’ve been with for 10 years now. Jason has helped me grow into a much better person and loves me unconditionally. He supports me in everything I do and encourages me to follow my dreams. I have 2 stepsons who have given me a run for my money but I still love them both at the end of the day. They are growing up so fast and I’m proud of the young men they are becoming. After an incredibly challenging fertility journey, I have my almost 5 year old daughter who is bright, caring, funny, and wise beyond her years. She is the light of my life and the reason I smile every day. I always tell her she saved my life, and it's true, but I won't tell her how until she's much older.

I have a passion for traveling and exploring new places. We try to do a big family vacation once a year and just this year decided that one trip a year should be spent nurturing our relationship. I love animals and have two dogs and three cats who keep me company and make me laugh. I’m on a journey to self love after spending my entire life as an overweight underdog. I’ve struggled with my body image and self-esteem for as long as I can remember, but I’m learning to accept myself and love myself for who I am. I have a daughter now, and I owe it to her to be kind to myself as the way I behave in front of her will be a reflection of how she treats her own body.

I live with many invisible illnesses both mentally and physically but try my best to get through every day. Some of the conditions I deal with are anxiety, depression, PTSD, OCD, ADHD, insulin resistent PCOS, Chronic Kidney Disease, chronic fatigue syndrome, migraines, and more. Yeah, I know, it fucking sucks. But, I'm definitely not here to gain pity for my health problems. By looking at me, you'd think the only problem I'd had in my life was enjoying one too many cheeseburgers. Some days are better than others, but some days are really hard. I try to be positive and optimistic, but sometimes I feel hopeless and overwhelmed. I’m grateful for the support of my family, friends, doctors, therapists, and online communities who help me cope and understand that I’m not alone.

I grew up in Guelph, Ontario and ventured back to Sudbury, Ontario after leaving my now ex-husband which was the best decision I’ve ever made. He was an interesting choice to say the least, and for the longest time I felt so trapped. It took me a long time to gather the courage to leave him, but when I did, I felt free and empowered. It was a turning point in my life that led me to meet my current husband and start a new chapter.

I’m thankful for this beautiful life I live. It’s not perfect, but it’s mine. And it’s full of love, laughter, learning, adventure, growth, gratitude, and hope. Thank you for reading this post even though you're probably rolling your eyes at yet another new overnight brainchild. But I'm going to try to use this as an outlet to heal and grow from the shit life throws my way, and hopefully inspire others to do the same along the way.

[fromchaostocosmos]

The fact that many americans, especially of younger generations and from marginalized groups, will hobble together medical care from a sort of online collectivism is horrifiying.

I want to say look at the beauty of humanity and how we help each in times of need & come up with solutions and it isn't wonderful how med students will help to the best of their abilities to total strangers or doctors from other countries will help and people who have had the same problem will chime in.

Which yes is true, and it is in a way beautiful and say a lot humans as a whole and is lovely.

But it should not be this way. It is at the end of the day a horrific indictment of the USA health system. That people can not get health care. That people have cobble together something and hope it works and solves the problem. That people can not afford to go get medical care. Can not afford insulin, epi pens, glasses, asthma medication, mental health care, pacemakers, to give birth, everything, anything, all of it

People in the USA die from things that are so treatable and fixable that it should be incredulous that anyone is dying from it because they can not afford to get it treated

People in the USA have don't actually have access to medical care. What is going on with on medical care and access to it is criminal. It should be treated as a war crime.

It is the theft and murder of The People, so it doesn't count as a crime I guess.

(isn't state sanctioned murder of it's people the sort of thing the UN is supposed to care about, supposed to do something about, supposed make a fuss over? where are the amnesty groups? our gov may not be dropping bombs on us at the moment, but don't think they aren't killing us, I mean look at the bills they pass, the fact that we can't afford to go to fucking doctor)

[mywheelieweirdlife]

I realised tonight that I struggle telling my new partner about my disability despite him being the most loving, supportive, wonderful person and one of my closest and best friends who is absolutely amazing with my conditions and already just automatically takes initiative to look after me before I'm even worried about my symptoms... like he goes 'that's not normal and okay' and just goes and does whatever I need, sometimes only asking permission because he knows I need something but can't do it and I don't like asking for help.... because my ex boyfriend was so ashamed of me that I literally can't wrap my head around the fact my current boyfriend can love me this much.

Because I was too loud, too bouncy, too much, too weird, because people stared when he kissed the person in the wheelchair and they made comments and because I was disabled and needed help and he didn't know what to do and wasn't able or willing to do it and refused to listen.

To the point where I'm surprised that my boyfriend got me a glass of water when I was in pain and he looked at me and went 'Ashley, that's lower than the bare minimum and you deserve so so much more than that' and then I cried about it for a week.

And that tonight, he took care of me with low blood sugar, and once we got home and I said it was definitely a wheelchair night because my legs were absolutely about to go, he undid my shoes and took them off for me and set up my wheelchair and then once I was in my chair, he just stood there cuddling me and playing with my hair for a minute and told me that I was beautiful and he's so lucky to have me.

He kisses me in public, he holds me in public, he pushes me around when I'm tired and flirts with me and tells me how cute it'll be when our little polycule has kids and he makes me feel beautiful and good and I laugh when I'm with him like I haven't in a relationship since fucking 2017.

And this absolute dork of a human, who loves me and I genuinely don't think he could ever be embarrassed by me based off the chaos we are together and how much he genuinely worships me (and it goes both ways)... I can't get myself to tell him everything that I hide about my disability.

The things only my best friend knows. The things I say in-front of him to friends in medical terms bc they're also disabled and we nod and get it and we lowkey discuss symptoms, but like, how do you just tell someone the symptoms of 'I have a weak pelvic floor because of an injury that my body decided to shut down from and now half the muscles in my pelvic floor have lost muscle tone and I'm trying to learn how to use them again but my condition also just turns them off sometimes' and that 'I deal with an injury that ruined my gut bacteria so on-top of that and muscle problems, sometimes my digestive system just stops for ages but I have a hormonal condition that fucks with insulin production so I still have to have something so I mostly have liquids and occasional solids until it turns back online and that has some not fun side effects.'

Or the good old 'I have cramping through my entire body during some flares that sometimes makes me an insufferable bitch to be around because I'm in so much pain I literally can't function or breathe through them and all I can do is try to sleep for a few days until it ends and I will not want you anywhere near me or my bed during those flares.'

And that maybe some of my conditions and concerns will change with treatments, but some of these are from the physical symptoms of traumas long term after effects because even if I can stop what caused the damage doesn't mean it'll 100% fix the damage.

I might be able to stop the automatic stress response that starts creating muscle tension so extreme it literally paralyses me... or I might have actually caused some nerve damage through that over the year and some of the sensation in my body may have been lost a little or be hypersensitive because my body is terrible with limits.

Like there was a time when I wasn't ashamed or embarrassed by this, because it's human and it happens and I was hurt and this is what happened from it... but that one ex who would constantly fight with me because he was so embarrassed of me and who I am, completely broke my sense of self and my self esteem by deciding my normal didn't matter.

That my body and my disability was too hard for them so they did very little to protect or help me and even when they did, they complained about it and I felt like a burden.

And my boyfriend doesn't make me feel like that ever, he's struggled to get my wheelchair in his car, but his response to that was about working out what he needed to move in the car. I had a seizure while out, a really bad one, and he carried me to my best friend's car, carried me inside when we got home after getting me coffee and put me on my bed and stayed there looking after me and cuddling me and we played CAH with my best friend and my niece.

Like this man has never given me a reason to doubt that he would do anything for me, he held my drunk ass up in the shower at my cousins after I got a smidgen too drunk to be safe on my own. And he also reminded the entire time that I was okay and safe and he loved me and wasn't there for anything but to get clean with me and make sure I didn't fall on my ass again that night.

And I trust him with everything I've got, I've always felt physically safe with him and as we've grown older and he's grown tf up a little (because guys in their early 20's are stupid, he's a few years older than me, but like, in the 2-3yr older range, not the creepy range) we've finally matched maturity and life points really well and everything just aligned perfectly for us and we realised we were more than friends... I trust him with more and more, including some of my biggest secrets and traumas and my dramatic personality.

But I can't wrap my head around how to trust him with the full extent of my disability, not because I don't want to, but because I'm really scared to after my ex shamed me and made me so uncomfortable and embarrassed with the surface level of my disability that I don't have the words for the harder more private parts of my condition anymore.

And that just hurts. I want to let him in fully and I want someone to see all of me and all my struggles and challenges and everything that I am and that's a part of me and love me not despite or regardless, but through it and with it all.

I want to be seen and heard and loved… and he would immediately, without a single doubt, I would be shocked if he reacted in a way that hurt me because at this point I'm finally learning to not be anxious saying things that would start fights in old relationships because he'll just say he's proud of me for telling him and that he loves me and that it's okay and he's here for me and ask what he can do to be supportive during the hard times.

But that fear and the look on my ex's face when I anxiously showed him videos by another wheelchair user who created entire YouTube series on disabled living and my ex asking 'do I have to watch and know this' with a look that honestly haunts me to this day and is burned into my memory and soul because it's also the look my father has when someone mention periods or starts playing WAP... it stopped me from being proud of myself for the last 3 and a bit years.

And now I want to share myself with someone that I love and trust and I can't yet and I hate it.

It's also why I'm writing my book. Because fuck we all deserve to feel good regardless of our disabilities and no one should be hurt like this because someone said stupid shit projecting their insecurities and bullshit onto us. I want to feel beautiful and sexy and passionate and be open and honest and optimistic about sex and living and working on this book (slowly af but it's still being worked on.) is helping a bit. The rest is shadow work, my friends and my partners.

But god I wish I could be more open and honest with myself and them about my struggles.

[marcu-bug]

Hi, I hope you are doing well.🌹

Can you help by sharing my story, reblog, and donating if you can, to keep hope alive for me, I'm type 1 diabetes. I am calling on your humanity and kindness to help me raise $340.

This amount will enable the approval of an insulin pump that will help me better control my diabetes. Although I am happy that I have been approved the hardest part is the money to pay for the pump and equipment, please your contribution is important. Be blessed ♥️

Hi! Unfortunately Im able to donate due to not having my own means of sending or donating money online . But I'll be happy to spread the word.

To the peeps reading this post, please help spread the word and donate if you can. We wish you the best of luck, Zanylandwhispers!

[fitnesswithsarm]

Common Myths and Misconceptions About Ibutamoren MK-677

Ibutamoren MK-677 is gaining recognition in fitness circles. It’s regularly promoted as a compound that boosts growth hormone degrees. However, there's quite a few confusion and misinformation surrounding it. Let’s resolve some of the most unusual myths and misconceptions about Ibutamoren.

Myth 1: Ibutamoren is a Steroid

One of the biggest myths is that Ibutamoren is a steroid. This is not true. Ibutamoren is a growth hormone secretagogue, that stimulates the body to produce more growth hormones. Unlike steroids, which are synthetic versions of testosterone, MK-677 targets growth hormone production and insulin-like growth factor 1 (IGF-1). If you’re considering using it for muscle growth or anti-aging, you may want to buy MK 677 for its benefits, but knowing it’s not a steroid is crucial.

Myth 2: Ibutamoren Causes Uncontrolled Muscle Growth

Some humans assume Ibutamoren will result in an intense, fast muscle boom, just like anabolic steroids. This is another false impression. While Ibutamoren can assist with muscle protection and restoration, it does not motivate uncontrolled or big muscle growth. The adjustments it promotes are slow and depend upon a proper weight loss plan and consistent workout. It's not a "magic tablet" for instant bulk.

Myth 3: Ibutamoren Has No Side Effects

No supplement or SARM is free from side effects. Ibutamoren is not exclusive. Common side effects may encompass water retention, expanded appetite, and possible insulin resistance. While it’s frequently advertised as safe, using MK-677 without clinical guidance can lead to undesirable consequences. It’s vital to be privy to how it might affect your body, especially with long-term use.

Myth 4: Ibutamoren Boosts Testosterone Levels

Many humans believe that Ibutamoren increases testosterone degrees. In truth, Ibutamoren frequently affects growth hormone and IGF-1 stages, not testosterone. While it may assist with muscle growth and recuperation, it won’t have the same hormonal results as testosterone boosters or steroids.

Myth 5: Results from Ibutamoren Are Permanent

Another false impression is that the gains from the use of Ibutamoren are everlasting. Unfortunately, this isn't authentic. Once you stop taking it, your body will possibly go back to its natural hormone ranges. This manner that muscle profits and fat loss can be reversed in case you don't keep a good weight-reduction plan and normal workout routine. The outcomes from Ibutamoren are lasting if you put in non-stop effort.

Myth 6: Ibutamoren is Only for Bodybuilders and Athletes

Although many athletes and bodybuilders use Ibutamoren, it’s not limited to just them. It’s also used for scientific purposes, including treating muscle-wasting diseases and boom hormone deficiencies. Older adults may additionally use it to enhance bone density and average energy. Its applications pass past the health enterprise, proving that it’s no longer just for elite athletes.

Myth 7: Ibutamoren is Legal and Easily Accessible Everywhere

Many expect that because Ibutamoren is popular, it ought to be legal and easy to get. However, the legal repute of MK-677 most SARMs online varies throughout the USA. In some places, it’s legal for research functions but not approved for human consumption. Always check the rules in your region before using it.

Myth 8: Ibutamoren Can Replace a Healthy Diet and Exercise Routine

Some consider that taking Ibutamoren will make up for a weight loss program or lack of workout. This is completely fake. While it could cause muscle increase or fat loss, it isn't a substitute for proper diet and regular workouts. MK-677 works great when mixed with a healthy way of life, not as a replacement for one.

Myth 9: The More Ibutamoren You Take, the Better the Results

There’s a risky perception that taking extra Ibutamoren will give you higher or quicker effects. Higher doses don’t necessarily imply higher outcomes. Overdosing can result in side effects like bloating, fatigue, or maybe more excessive health issues. It’s vital to follow the advocated dosage and consult an expert if you're uncertain.

Conclusion

There’s several incorrect information surrounding Ibutamoren, however researching, you could make informed choices. It can help with muscle increase and results take effort and time. Always be aware of capability side results, and ensure to check the legal status before using. Above all, don’t count on it to replace the tough work that comes from maintaining a wholesome eating regimen and exercising daily.