#Colon inflammation

[queenboimler]

nothing worse than being someone who loves to be on a strict morning schedule only for my colon to decide it needs to throw a temper tantrum and make me late 😭

[newsjet]

Research Investigates Walnuts’ Role in Reducing Inflammation and Colon Cancer Risk

ISTANBUL, Türkiye – (ARAB NEWSWIRE) — New findings published in Cancer Prevention Research show daily walnut consumption may improve markers of systemic inflammation and reduce colon cancer risk. Colon cancer is one of the most common cancers worldwide and accounts for around 10% of total cancer diagnoses.1 Urolithin A (UA), a metabolic byproduct of the plant-derived polyphenols, ellagitannins,…

[anftherapy]

Meet PT. Waleed Alshedukhi, our highly skilled ANF Therapist and certified ANF Instrcutor based in Saudi Arabia. With expertise in: ✔️ Diagnosis & rehabilitation of sports injuries ✔️ Lymphatic system care ✔️ Colon health ✔️ Migraines & headaches ✔️ Herniated discs ✔️ Men’s health ✔️ Advanced, cutting-edge treatment methods

Waleed is dedicated to bringing effective solutions to complex health issues. He also frequently organizes workshops and training sessions across Saudi Arabia, helping both patients and medical professionals discover the power of ANF Therapy®.

[little-eye-guy]

kind of messed up that everything is connected. my colon has ulcers which means i also have arthritis and psoriasis. i simply think that should not happen

[david-ojcius]

Free article: A subset of NLRs function to mitigate overzealous pro-inflammatory signaling produced by NF-κB activation. Under normal pathophysiologic conditions, proper signaling by these NLRs protect against potential autoimmune responses. These NLRs associate with several different proteins within both the canonical and noncanonical NF-κB signaling pathways to either prevent activation of the pathway or inhibit signal transduction. Inhibition of the NF-κB pathways ultimately dampens the production of pro-inflammatory cytokines and activation of other downstream pro-inflammatory signaling mechanisms. Dysregulation of these NLRs, including NLRC3, NLRX1, and NLRP12, have been reported in human inflammatory bowel disease (IBD) and colorectal cancer patients, suggesting the potential of these NLRs as biomarkers for disease detection. Mouse models deficient in these NLRs also have increased susceptibility to colitis and colitis-associated colorectal cancer. While current standard of care for IBD patients and FDA-approved therapeutics function to remedy symptoms associated with IBD and chronic inflammation, these negative regulatory NLRs have yet to be explored as potential drug targets. In this review, we describe a comprehensive overview of recent studies that have evaluated the role of NLRC3, NLRX1, and NLRP12 in IBD and colitis-associated colorectal cancer.

[literaryvein-reblogs]

Hi, sorry to bother and sorry if this is too much, but I was wondering if you had anything to help write a character dying of an infected gunshot wound? Love ur acc btw 💓

Writing Notes: Infected Gunshot Wound

It will take some time for a gunshot wound to heal.

The length of time depends on the person's health and how serious the wound is.

The bullet may have broken a bone or caused a lot of damage to muscles, organs, or nerves.

The bullet may also have been left in the body because getting it out would have caused the person more harm.

Some signs of infection:

Redness or swelling around the wound

A lot of blood or pus coming from the wound

Foul odor

Fever of 100.4°F (38°C) or higher, or as directed by provider

It's normal to feel some stress and anxiety after a traumatic event like a gunshot wound. You may write about your character feeling anxious, angry, or depressed or having trouble sleeping or focusing. The following may also occur.

Wound continues to bleed even after putting direct pressure on it

For chest, back, or abdomen wounds:

Shortness of breath

Painful breathing

Back or abdomen pain that gets worse

Weakness

Dizziness or fainting

Redness, swelling, or fluid leaking from your wound that gets worse

Pain that gets worse

Symptoms that don’t get better, or get worse

New symptoms

Signs of Wound Infection

Pus: Medical professionals manage healthy drainage with regular dressings. But cloudy, yellowish drainage or purulent discharge with a pungent or foul odor accompanied with swelling and elevated pain is a sign of an infected wound.

Pimple: When a pimple-like crust forms on an injury, it indicates an infection. This pimple increases in size over time.

Soft Scab: While it is normal to have slightly pink or reddish skin around the injury, a scab that constantly increases in size over time could indicate an infection.

Red Area: In the initial stages, wounds appear red due to the natural healing process. But if the red area around the injured site continues to increase even after 4-5 days of an injury, it is a telltale sign of an infected wound.

Red Streak: If a red streak starts forming from the injured site towards the heart, it could be lymphangitis (inflammation of the lymphatic system). This underlying infection requires immediate medical attention.

More Pain: Normally, the pain subsides a few days after an injury or wound. Long-lasting or elevated pain even after a few days is a symptom of an infected site.

More Swelling: Similar to redness around the wound, swelling in the affected area indicates that the body’s immune system is working. But if the swelling continues even after 3-5 days, with no signs of it reducing, it indicates an infection.

Swollen Node: Generally, swollen lymph nodes indicate that a body’s immune system is fighting an illness. But the formation of a large and tender node near the injured site could be a sign of an infected wound.

Fever: After an injury or surgery, it is normal for a patient to run a low-grade fever. However, persistent high-grade fever coupled with decreased appetite and body ache is a sign of infection.

An intermediate velocity (muzzle velocity 350-650 meters per second or 1,200-2,000 feet per second) and a high velocity (muzzle velocity >600 meters per second or >2,000 feet per second) gun shot wounds are more likely to have a high risk of infection.

It has been found that gunshot wounds to the abdomen with associated colonic injuries had a worse outcome with an increased risk of developing wound infections.

Necrotizing Soft Tissue Infection. A serious, life-threatening condition. It needs treatment right away to keep it from destroying skin, muscle, and other soft tissues.

The word necrotizing comes from the Greek word "nekros."

It means "corpse" or "dead."

A necrotizing infection causes patches of tissue to die.

These infections are the result of bacteria invading the skin or the tissues under the skin. If untreated, they can cause death in hours.

Fortunately, such infections are very rare. They can quickly spread from the original infection site. So it's important to know the symptoms.

The most common symptoms of a necrotizing soft tissue infection:

Pain that hurts more than you think it should, based on the size of the wound or sore

A wound with a fever (higher than 100.4°F or 38°C) and a rapid heartbeat. This is usually more than 100 beats a minute.

Pain that extends past the edge of the wound or visible infection

Pain, warmth, skin redness, or swelling at a wound, especially if the redness is spreading rapidly and if areas are turning bluish or black

Skin blisters, sometimes with a "crackling" sensation under the skin

Pain from a skin wound that also has signs of a more severe infection, such as chills and fever

Grayish, smelly liquid draining from the wound

A small sore or pus-filled bump that is unusually painful to the touch

An area around the sore that is hot to the touch

A hard time thinking clearly, especially along with one of the other symptoms noted

A lot of sweating, especially with one of the other symptoms noted

Areas of skin at or near a wound that feel numb

A sore that is getting worse quickly, especially if you:

Are obese

Have diabetes

Have a weak immune system from using a steroid regularly

Are on chemotherapy for cancer

Are on dialysis

Have peripheral artery disease

Drink a lot of alcohol

Have poorly controlled HIV/AIDS

People with some of these symptoms are surprised to learn that they have a necrotizing soft tissue infection.

That's because it may not seem to be very severe at first.

But these infections can get worse quickly if they are not aggressively treated.

Sources: 1 2 3 4 5 ⚜ More: References ⚜ Writing Resources PDFs

Here's another reference that includes some mechanisms at work with gunshots. And more information on wounds.

Thanks for this request, this was quite interesting for me to look up—no apologies needed! And thank you for your lovely words, hope this helps with your writing <3

[covid-safer-hotties]

Also preserved in our archive

Not exactly new news (published in June) but something that's important and a bit underdiscussed.

By Devika Rao

Rare types of cancer are showing up in higher numbers since the Covid-19 pandemic. Doctors suspect that the virus itself may be contributing to the higher cancer rates, despite a solid connection not yet being established. The pandemic may have permanently altered the bodies of those infected, making them more susceptible to cancer. Those affected include people who were otherwise previously healthy.

What do cancer trends look like? Doctors have identified a marked increase in late-stage rarer cancers in people who had otherwise been healthy. Lung, blood and colon cancer, especially, have been rising in younger people. Specifically, medical experts have observed a rise in new cancer patients, multiple patients with multiple cancers, couples and siblings developing cancer within months of each other and cancer patients relapsing after years of remission.

The trend has been particularly noticeable since the Covid-19 pandemic. "This is an observation that has piqued the researchers' and clinicians' interest, that, is there an association with Covid, especially long Covid and cancer?" Dr. Suraj Saggar, chief of infectious disease at Holy Name Hospital in Teaneck, New Jersey, said to Fox 5 New York.

Cancer is caused by errors in genetic code within cells. "The human body is made up of trillions of cells in a constant state of growth, repair and death," said The Washington Post. "Most of the time, cells with damaged DNA fix themselves, or simply disappear. Sometimes, they start collecting mistakes in their genetic code and rampage out of control into tumors."

What is more alarming is the prevalence of people suffering from more than one type of cancer. "Having multiple forms of cancer at the same time has also become more prevalent. Cancers typically start in one part of the body and spread," the Post said. "It's rare for discrete cancers to begin in different parts of the body during a short window."

What could be causing the rise? Some scientists posit that the Covid virus itself could be contributing to the higher numbers of cancer diagnoses, especially for those who are suffering from long Covid. "The idea that some viruses can cause or accelerate cancer is hardly new," said the Post. "Scientists have recognized this possibility since the 1960s, and today, researchers estimate 15% to 20% of all cancers worldwide originate from infectious agents such as HPV, Epstein-Barr and hepatitis B."

Because "infection with SARS-CoV-2 occurs in several organs either directly or indirectly, it is expected that cancer stem cells may develop in multiple organs," said a 2023 study published in the journal Biochimie. Lung, colorectal, pancreatic and oral cancer could particularly be exacerbated.

While not officially confirmed, the virus is said to cause full-body inflammation. "Inflammation triggers many genetic changes in a genome that can create a propensity of developing cancer in certain individuals," Dr. Kashyap Patel, CEO of Carolina Blood and Cancer Care Associates, said to News Nation. "We are completely under-investigating this virus," Douglas C. Wallace, a geneticist and evolutionary biologist at the University of Pennsylvania, said to the Post. "The effects of repeatedly getting this throughout our lives is going to be much more significant than people are thinking."

mentioned study: pmc.ncbi.nlm.nih.gov/articles/PMC10202899/?s=09

[astroyongie]

Hi yongie! Can you do a reading of TXT’s current physical and mental health? Please and thank you!!

TXT Current Health

-> Note: Please take it as a grain of salt as this is done through tarot. Also TW: EDs, addictions

Yeonjun

- 🩺: The cards are showing that physically Yeonjun seem to be really exhausted. There's something related to his nervous system and his brain in general but more like a consequence of mental fatigue and also sleep cycles that aren't being done properly. Despite that he has been recovering from this, as there's some convalescence energy here. Mentally, this man is definitely going through a burnout as there's a lot of stress related conditions around him that can induce chronic fatigue, insomnia, depression and anxiety.

Soobin

- 🩺: When it comes to Soobin, the cards are suggesting some major health changes at the moment. There's nothing going on physically beside the fact that he has to be careful with his reproductive organs, colon, bladder and immune system. His energy is mostly centered on the mental aspect of it with a lot of psychological transformation going on. I believe he is trying to let go of unhealthy habits.

Beomgyu

- 🩺: Well the first thing I noticed on the cards for Beomgyu is the fact that he needs to be really careful with physical injuries from dancing or impulsive behavior he might have that can impact his physical health by making injuries. The areas of his muscles, legs, adrenal glands and overall head need to be looked for so he doesn't hurt himself in the near future. When it comes to his mental health, we have got a lot of restlessness, impulsivity and short attention span (sounds like ADHD in a way but I am not making any diagnosis here, just pointing out). Well, in any case he is currently prone to have inflammation, fevers, accidents due to being reckless, burning himself or stress from overactivity

Taehyun

- 🩺: Please take it with a grain of salt. For Taehyun, he spread has mostly been pointing out for an addition issue that has been impacting his physical health. This addiction can be for example substance abuse, food, sex or something else. In any case it's bringing a lot of toxicity in his body. I see mostly illnesses related to these addictions, eating disorders, STIs, obsessive compulsive patterns and self-destructive behavior. He needs to look out for issues with his sexual organs, skin, digestive system (especially in relation to toxins) and his lower back. Mentally, I would maybe point of some issues with obsessive thought, depression, dependency and compulsive behavior.

Kai

- 🩺: Finally when it comes to Kai, the cards are rather positive and showing an overall stable health, both mentally and physically. He has been focusing on his well being in a long term way which is rather positive. I would maybe just say that he needs to look out for issues in his bones, joints, skeletal system and legs and also maybe illnesses like hereditary conditions and arthritis. Mentally, there's emotional grounding so he is honestly in a good shape.

[wcndersouls]

I hate when I have my flare up days and everyone points out “you look sick.”

I know it’s showing. I can fucking feel it bro. ✌️

Or when I don’t have the bad flares and I hear, “but you don’t look like you’re sick.”

I’m sorry let me just pull out my colon & esophageal polyps for you to see??? The holes in my intestines & inflammation too??? Do you need my scans???

I think that if you’re someone who hasn’t dealt with these things, you shouldn’t be commenting like that. You have no idea what it can be like. While I can fake smiles for cameras and pretend life is normal (which btw I used filter!), my life is not normal. You see me have photography adventures (my last hope) as I wanna pursue that again? Well, I couldn’t leave my house in years until some recent recovery now! It’s a slight miracle & I worked so hard to fix medical errors doctors made on me. I have to carry my own personal mini med kit. You don’t see what goes on privately. It is a rollercoaster and there is a lot to it.

[darkmaga-returns]

Four years ago, I read an autopsy report of eight COVID-19 patients (paper linked in my 2021 post). The report noted the curious finding that two of the eight had previously unknown thyroid cancer. Given that my research at the time had already led me to believe the virus was carcinogenic, this discovery further bolstered my resolve that I was on the right track. Thyroid cancer is rare. It accounts for less than 1% of cancer diagnoses in the US each year.

Thyroid cancer is relatively uncommon compared to other cancers. In the United States, it is estimated that in 2021 approximately 44,000 people will receive a new diagnosis of thyroid cancer, compared to over 280,000 with breast cancer and over 150,000 with colon cancer.

Thyroid Cancer (Papillary and Follicular) https://www.thyroid.org/thyroid-cancer/

As I stated in my post of 2021, the odds of 25% of any population having thyroid cancer, especially undiagnosed, would be statistically almost impossible. I hypothesized that either direct infection by SARS-CoV-2, its reactivation of EBV (another risk factor for thyroid cancer) or both were most likely a factor.

I believe both instances are due to SARS-CoV-2 infection. One due to direct thyroid infection and the other due to an active infection of or reactivation of EBV. EBV is considered a significant cause of papillary thyroid cancer. Perhaps both factors are in play as EBV could have been active in both patients and the body may have cleared the virus in the other. A study from Wuhan University published 25 May found that EBV/SARS-CoV-2 coinfection was associated with fever and increased inflammation. EBV reactivation may associated with the severity of COVID-19.

[themostefficientwaywithwater]

In Scarlet and Violet, the only thing they tell you about what happened to Arven's mabostiff is that he got severely wounded by a paradox pokémon and that's why his health declined. But we never see an open wound on him, and I always found it strange that pokemon centers can't heal such an injury.

So here's my headcanon: the cause of mabostiff sickness wasn't the injury he received from a paradox, but an infection.

Paradoxes are pokémon from the far, far, far past/future, a period of time with organisms entiretly different that the ones in the current time. That includes pokémon... but also includes microorganisms. Paradoxes sent to the present carry bacteria that are entiretly different to the ones we have, to the ones we made antibiotics for, to the ones we've adapted to. Pokemon from the present thus have no defenses and no drugs that can combat an infection caused by those pathogens. So the consequences of being infected by a past/future pathogen are way, way more dire than catching a common cold or a food intoxication. This was actually used as biological warfare in the past, by colonizers sending contaminated material to insulated societies: because they didn't had contact with the bacteria, they had no defenses to them so they either died or got so sick they had no chance against their conquerors.

So, Mabostiff was hurt by a carrier of a foreign pathogen that modern medicine cannot combat. His only defense is his own innate immune response, which includes inflammation, which is a strong response intended to destroy any pathogen that manages to break through your body natural barriers... but can also prove fatal to the affected, as the increase in body temperature denaturalizes the protein of both pathogens and host. It's, basically, like trying to get rid of a plague of cockroaches by setting your house on fire and then praying that the house lasts more than the cockroaches.

I don't think that herba mystica actually *cured* him, but they certainly did help. Herba mystica seem to be related to Terapagos' crystals, as they only grow in Area Zero or other locations with tera crystals (like crystal caverns in Paldea, Kitakami and BB's Terarium), and the professor confirms that these crystals enhace both machines and living beings. This is why titan pokémon and the loyal tree get stronger after eating herba mystica and mochis respectively (mochis are made with "special herbs", and have the same effect as when titans ate herba mystica, so it's reasonable to think they're it's main ingredient). The herba mystica strengthened Mabostiff the same; it's just, that new strength was used to *survive* it's own immune response, to hang a little bit longer, until it's body finally got rid of the pathogen. This also explains why Mabostiff got into shape right after being cured, instead of spending a few days/weeks recovering: the power of the herba mystica allowed him to survive his infection with minimum damage, and to heal faster.

I guess technically it wasn't necessary that Mabostiff ate all the different herba mystica, that was just misinformation Arven had read (just like spicy herba mystica being able to make you "flush toxins through sweat", that's not how sweat works!), and it can be proven since there's a sixth one (umami?) that Amarys gives you after the indigo disc plot, one that Mabostiff didn't eat, yet he recovered still. It's just a coincidence that each of the titans guarded different flavors (and also a way for the game to teach you about them). Mabostiff just needed to consistently eat them, until his infection was fully gone.

So, TLDR: Arven's mabostiff illness wasn't just because he was injured by a paradox pokemon, but because that wound got infected by a pathogen from the past/future. He got so sick because he had no specific defenses against it, and no cure had been invented yet. Herba mystica didn't cure him, they just enhaced his organism so it could resist a prolongued inespecific immune response, buying him time until his body finally eliminated the pathogens.

[ozzyonedge]

May 19th is World IBD Day.

IBD stands for Inflammatory Bowel Disease which are mainly Crohn's Disease (CD) and Ulcerative Colitis (UC)

Via Wikipedia:

Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine, with Crohn's disease and Ulcerative colitis (UC) being the principal types. Crohn's disease affects the small intestine and large intestine, as well as the mouth, esophagus, stomach and the anus, whereas UC primarily affects the colon and the rectum.

IBD is a complex disease which arises as a result of the interaction of environmental and genetic factors leading to immunological responses and inflammation in the intestine.

[sicktember]

Hi! I was hoping for clarification on prompt 5 rouge organ! I was guessing it to be swelling/inflammation but I'm unsure

At first I thought it said Rouge organ and was super excited to try to write something like that. It's funny to imagine the organs gaining freewill and trying to escape

Thank you!

It appears that we have misspelled Rogue for Rouge. Because we are human, and autocorrect was utterly useless in this situation. 😬 We will get that fixed.

You've got a great idea going on there! Haha! We love it and it's right in line with what we actually meant!

But in case anyone needs a clarification on what a Rouge Rogue Organ is:

Several organs in the body are considered non-essential. If they become chronically inflamed or damaged they can be removed without causing major hardships on bodily function. We listed a few beside the prompt but there are others: Adnoids, appendix, gall bladder, reproductive organs, one kidney, part of the liver, the spleen, tonsils, and for a stretch- wisdom teeth.

There are other organs you can live without but they would require some medical intervention to replace their function. Like the colon or stomach.

When we chose the prompt Rouge Rogue Organ, what we had in mind was a sick character suffering illness, not because of germs but because one of their own organs had turned against them!

But, as always, feel free to stretch the prompt as far as you'd like! A fic from the Organ's POV sounds fantastic. Reminds us of the Awkward Yeti comics!

[buttfrovski]

pikn eye

Conjunctivitis occurs when the conjunctiva becomes inflamed due to an infection or an irritant. As a result of this inflammation, the blood vessels in the conjunctiva dilate, causing redness or hyperemia, and the conjunctiva can also become swollen.

The inflammation affects the entire conjunctiva, and depending on the cause, discharge may also be present. Bacterial conjunctivitis occurs when the eye's surface tissues are colonized by normal flora like Staphylococci sp., Streptococci, and Corynebacteria. The epithelial covering of the conjunctiva is the primary defense mechanism against infection, and any disruption in this barrier can lead to infection.[39] Secondary defense mechanisms include immune reactions carried out by the tear film immunoglobulins and lysozyme, conjunctival vasculature, and the rinsing action of blinking and lacrimation.