#Cold Storage Company in Ahmedabad

[blueiceindia]

Best cold storage manufacturers in India

We are a leading manufacturer of cold storage rooms.

Cold storage rooms are very helpful for keeping food since they control the temperature and humidity of grains and other food items.

Little refrigeration units to enormous cold storage facilities are among the goods we provide, and we frequently develop specialised solutions depending on the unique requirements of our customers.

Cold storage facilities can be used to store temperature-sensitive commodities safely and without running the danger of them becoming bad or losing their freshness.

Cold storage rooms are the most frequently used because they are dependable and won't let you down.

[mehuloffpage]

Milk processing plant manufacturer in India

We “Saffron Machinery” have gained success in the Milk processing plant manufacturer in Indian market by Manufacturing and Exporting a remarkable gamut of Dairy Machinery, Milk And Dairy Plant, Milk Storage Tank, Juice Processing Plant, Industrial Chiller, Ice-Cream Processing Machinery And Plant, CIP System, Bulk Milk Cooler, Mango Processing Plant, Fruit & Vegetable Processing Plant, Cold Room, etc. We are a well-known and reliable company at Ahmedabad (Gujarat, India). Our offered products are manufactured in compliance with the pre-defined industry norms and tested to ensure their flawlessness. Our Mission is To discover, deploy, develop and direct the available resources to enable them to demonstrate their optimum capacities to attain the highest possible level of productivity, profitability and customer satisfaction. Providing self employment in Rural India thereby improving their standard of living. We also Offering Industrial Erection Service to Our Client.

Incorporated in 2016 as Saffron Machinery with State-of-the-art Manufacturing unit of Dairy Equvipment, Food Processing Plants, Industrial Chillers And Amonia Chilling Plants,cold Rooms.

Highly skilled, dedicated, experienced work force.

[coninframachinerypvt]

Paving the Way to Success: Coninfra Machinery Pvt. Ltd.'s Asphalt Batch Mix Plant Process

Introduction

In the realm of construction and road infrastructure, the name Coninfra Machinery Pvt. Ltd. shines brightly. This dynamic company has been at the forefront of delivering cutting-edge solutions for over a decade. One of their standout offerings is the Asphalt Batch Mix Plant, which plays a crucial role in the construction of durable, smooth, and long-lasting roads. 

In this blog, we'll dive into Coninfra's Asphalt Batch Mix Plant process, shedding light on how it's helping pave the way to success in the industry.

The Importance of Asphalt Batch Mix Plants

Before delving into Coninfra's process, let's understand the significance of Asphalt Batch Mix Plants. These plants are pivotal in producing high-quality asphalt mixtures, which serve as the building blocks for roads and other surfaces. The mixture includes aggregates, bitumen, and filler material, all carefully blended to create asphalt that meets specific quality and performance standards.

The Coninfra Asphalt Batch Mix Plant Process

Aggregate Feeding: The process begins with the feeding of cold aggregates into the feeders. These aggregates are stored in different bins, each containing a specific size of aggregate. This meticulous organization ensures precise blending and consistency.

Drying and Heating: The aggregates are then transported to the drying drum, where they are exposed to a controlled heat source. This step removes any moisture from the aggregates, a crucial factor in achieving the desired asphalt quality.

Filler Material Addition: Simultaneously, the filler material is added to the mix. This component enhances the properties of the asphalt mix, ensuring it adheres properly and resists cracking.

Bitumen Addition: The heart of the process is the addition of bitumen, the binder that holds the asphalt mix together. Coninfra Machinery Pvt. Ltd. employs advanced technology to accurately meter and add the bitumen to the mix, ensuring the right proportion for a durable result.

Mixing: Once all components are in place, they are blended in the mixer unit. The mix is thoroughly mixed to ensure even distribution of bitumen and other materials.

Gradation Control: Gradation control is vital for asphalt mix quality. Coninfra's Asphalt Batch Mix Plant employs sophisticated systems to monitor and control the gradation, ensuring that the final mix meets industry standards.

Loading and Storage: The finished asphalt mix is loaded into trucks or storage silos for transportation to the construction site. Coninfra's Asphalt Batch Mix Plants are designed to be efficient and user-friendly, streamlining the loading and storage process.

Quality Assurance: At every step of the process, quality control measures are implemented to ensure that the asphalt mix adheres to the required specifications. Coninfra is committed to delivering high-quality asphalt that meets the demands of modern infrastructure projects.

Conclusion

Coninfra Machinery Pvt. Ltd.'s Asphalt Batch Mix Plant process exemplifies its dedication to providing innovative and efficient solutions for the construction industry. Through precise material handling, advanced technology, and quality control, Coninfra ensures that the asphalt mix produced in their plants is of the highest standard. This commitment to excellence not only contributes to the longevity of roads and infrastructure but also plays a significant role in the success of construction projects. Coninfra's Asphalt Batch Mix Plant process truly paves the way to success in the industry, one road at a time.

Name: Coninfra Machinery Pvt.Ltd 

Address:504, Sahitya Business Park, Nr. Keshav Hero Showroom , S.P Ring Road Nikol, Ahmedabad - 382350, INDIA

Contact No: +91 90999 41311

[tiapandayblogs]

Top Things to Look for in a Warehouse for Rent by a 3PL service provider

Getting a warehouse for lease is necessary, as it can save you space and the costs that you would have to pay for having your own storage space for stuffs to be sold in the future, or would be needed for manufacturing and production processes. Know about some of the most important things that you have to look for, while choosing a warehouse for rent by a 3PL service provider

Insurance

The onus of insurance lies with you to purchase some insurance for your belongings, which can keep them covered against any type of loss. When your belongings are properly insured, these can be covered during transportation or storage, and will always be safe and secured. Many storage companies can also offer insurance, and you have to check whether your warehouse service provider offers the same.Type of refrigeration equipment on offer

If you are trying to hire a cold store for rent,You need to check the temperature range of the cold storage, value added service,type of products being stored.The storage and handling charges.Availability of reefer transport. Read more about ecommerce fulfillment and 3PL in Mumbai here.Type of storage offered

It is also essential when you take warehouse for rent to know the nature of storage tenure they offer ie. temporary or permanent storage. Also check where the storage facilities or warehouses of the company are located in. Whether you need warehouse in Hyderabad, warehouse in Mumbai or warehouse for rent in Delhi, you have to make sure that the 3PL service provider has facilities in those cities. Some of the 3PL service provider however, have a wide network and facilities in many states and cities across the country.

Source - https://warehouse.godamwale.com/blog/threepl/threepl-rent

[ken-research-market-research]

Increased Investment in Transport Infrastructure and Rising Demand from End Users has Influenced Growth in Logistics Industry: Ken Research Buy Now Impact of GST: GST has facilitated the reduction in the transit and turnaround times of trucks by removing the multiple state taxes which were applicable earlier.

[bharatref01]

Ice Cream Hardener: Its importance and benefits for Ice Cream manufacturer

There’s so much madness for ice creams. Why do people love ice creams? What is so special about the dessert? People wait in long serpentine lines for their turns during wedding ceremonies. Such is the attraction for the world over famous sweet. Ice Cream hardener manufacturer, and supplier is reinventing their product line to keep abreast with the market demands.      

It wouldn’t be an exaggeration to call this delicious ice candy dessert a hot favourites of millions globally. In this short blog, we are going to highlight a few main reasons why plenty of people relish the cold dessert and the importance of the ice cream hardener machine.

No matter what you like, or which flavour you prefer, there's an option for everyone. There are hundreds of flavours and varieties.                

Who doesn’t enjoy a mouth-watering scoop of their ice cream? The answer is almost all!  

Before we take a deep dive into the subject, it makes sense to introduce the machine in simple language as it will help readers to relate the content better.

Learning about the Ice Cream Hardener    

It is a scientifically designed product that helps in hardening ice cream and frozen food. The machine has found usage in various applications, including:        

Applications

Ice Candy

Frozen food

Unique features of the machine

A quality-driven machine is identified by numerous salient features. These include:

Energy efficient

Sturdy design

Durable

Easy to use      

Whenever you plan to buy this machine, don't forget to examine the above salient features. At the end of the day, production matters.

An inferior quality will hamper the production process of your ice cream plant. As a businessman, you would not like to face this situation. That’s why quality is important. Only buy the product from a prominent ice cream hardener manufacturer, supplier in Ahmedabad.                

Types of ice cream hardener  

Ice cream hardener manufacturer, supplier is manufacturing a wide range of ice cream hardener. Bharat Refrigerations, a leading manufacturer, supplier of ice cream hardener is manufacturing two types of machines:

Static

Tunnel      

Ice Candies change your mood

When your mood is down, you want to do away with sadness, just relax, and order your favourite ice candy. You will experience the change immediately. According to research, ice cream has all the ingredients to lift your sad mood. Whether you face sorrow or are defeated in a recent cricket match, just have ice candy. And relax!      

Summary      

Ice Candies and frozen food have become hot favourties among foodies globally. Preparation may vary from company to company. Foundation remains the same. Wherever you are, have it. And it's affordable.

If you are planning to set up an ice cream factory or a hangout joint, ensure that the ice cream hardener machine you are planning to buy meets industry standards.                                          

Let’s collaborate for a mutually beneficial partnership  

Bharat Refrigerations is a wholly-owned subsidiary of Ice Make Refrigeration Ltd., an acclaimed name in Refrigeration Products and Equipment since 1993. Our excellence-driven total cold chain solutions comprise Cold Room & Storage Room, Transport Refrigeration, Commercial Refrigeration, Refrigerated Container, Ice cream Hardener, etc.  

If you are searching for industrial and business chillers for your business, then end your search with Bharat Refrigerations! The company’s expertise in offering chilling plant solutions has been helping numerous businesses to meet their business requirements.    

Let’s collaborate for a mutually beneficial partnership.

[coldmanposts]

Save your temperature sensitive goods by storing them in Coldman’s Cold Storage in Chennai.

Cold Storage is a place where goods such as meat, vegetables, pharmaceuticals, dairy products are stored to avoid rotting of the goods from high temperature, the goods are stored in refrigerated or frozen storage facilities under 3 °C (38 °F) temperatures. Cold Storage reduces the wastages of the perishable commodities and thus providing remunerative prices to the growers. Coldman which is Cold Storage Company in Chennai will help you in storing your perishable goods in the non-rotten able area.

It is obvious that in the high temperature of Chennai commodities that need to be stored in cool place gets rotten because of hot temperature. Consumable products such as meat, fish and even medicines can get spoiled if not taken proper care. So to help you with this issue Coldman which is Cold Storage Company in Chennai will allow you to store all perishable commodities. Companies who deal with products such as meat which need to be transported to hotels, cafes, restaurants etc. have to make sure that the goods should be delivered safely without getting damaged. Other important costly raw materials like dry fruits, chemicals, essences and processed foods like fruit juice/pulp, concentrated dairy products, frozen meat, fish and eggs can be stored in our Cold Storage Company in Chennai. There are a lot of businesses out there that handle perishable or temperature sensitive products. Cold storage warehouses give them a place to store those products safely. But we aren’t just a way to store your goods; it’s a good way to ship them too. Cold Storage Company in Chennai will process, package, and deliver your goods almost anywhere in refrigerated couriers, meaning the temperature stays exactly how it should the whole trip. So if you think you want to store you temperature sensitive products in your own storage, then you can with knowledge of storing particular goods at a particular temperature. But the real problem arises when it needs to be transported from one place to another. To help you with this we also offer to transport your temperature sensitive products in our refrigerated courier vans when it is necessary so that it can stay how it needs to be. So what Types of Goods do we store? Meat and non-veg products: people who own slaughterhouses knows well that it need to be stored at a cool temperature at the same time unwrapped and hung so that air can circulate around them. As slaughterhouses mostly supplies to hotels, restaurant and other places where food is served to consumer should make sure it is clean and hygiene, non-veg products such as meats, Seafood, chicken etc. can easily get rotten by high temperature, so we keep it under 4°C (39°F) or colder. So that you can maintain your goodwill in the market. Dairy products: As the fat in dairy products absorb strong aroma from the around environment we store it in a separate storage room at temperatures of 2°C to 4°C (36° to 39°F). and we make sure is always kept clean.

[blueiceindia]

Cold storage manufacturing companies in India

Blue Ice India is a top Cold storage manufacturer and supplier in Ahmedabad, India. Purchase online from us we provide the large selection of cold storage at affordable price range.

You can contact us at: 8866230337

Email us on: blueiceindiaseo2022@gmail.com

[eagle-eyez]

https://ift.tt/eA8V8J

ZyCoV-D, a needle-free three-dose COVID-19 vaccine developed by Indian pharmaceutical firm Zydus Cadila received an emergency use license in India on Friday, after a government panel recommended the same to India's central drug authority.

The Ahmedabad-based pharma major had on 1 July applied for emergency use authorisation (EUA) with the Drug Controller General of India (DCGI) for the vaccine. The company said it has conducted the largest clinical trial for the vaccine in India in over 50 centres so far.

Why is this relevant?

ZyCoV-D is the world's first DNA vaccine against the SARS-Cov-2 virus infection, developed by an Indian company and become the sixth vaccine that has been approved for use in the country after Serum Institute's Covishield, Bharat Biotech's Covaxin, Russia's Sputnik V and the US-made Moderna and Johnson and Johnson.

It is also the first vaccine candidate in India that has been found safe for use in children above the age of 12. Countries like US, France and Germany are already at various stages of providing vaccines for minors. In India, apart from ZyCoV-D, Bharat biotech's Covaxin is also under trial for use among the 2 to 18-year-old population.

Zydus Cadila, that already has anti-COVID treatments available in the market claimed to have conducted the largest clinical trial in India so far at over 50 centers and the participants included people between age group 12 and 18 years. The Covaxin trial includes 525 minor volunteers.

How is it different from other vaccines?

 ZyCoV-D is a three-dose vaccine, unlike Bharat Biotech's Covaxin and Serum Institute of India-manufactured Covishield jabs.

However, the company said it has also evaluated a two-dose regimen for ZyCoV-D vaccine using a 3-milligram dose per visit and the immunogenicity results had been found to be equivalent to the current three-dose regimen.

This will further help in reducing the full course duration of vaccination while maintaining the high safety profile of the vaccine in the future, the company added.

ZyCoV-D is touted to be a 'needle-free' vaccine.

It is an intradermal vaccine, which is applied using The PharmaJet needle-free system.  Needle-free injectors deliver the vaccine using a narrow stream of fluid to penetrate the skin and deliver the vaccine to the proper tissue depth. The company says this methodology can eliminate chances of needlestick injury and will also lead to a significant reduction in any kind of side effects. It will also help people suffering from trypanophobia, a common condition marked by an irrational fear of blood or needles. It's estimated that fear of needles affects up to 25 percent of adults.

ZyCoV-D is not very sensitive to temperature, unlike its competitors. The prescribed storage temperature is between 2 to 8 degrees centigrade but has shown good stability at temperatures of 25 degrees centigrade as well for at least three months.

The thermostability of the vaccine will help in easy transportation and storage of the vaccine and reduce any cold chain breakdown challenges leading to vaccine wastage.

The plasmid DNA platform provides ease of manufacturing with minimal biosafety requirements.

It can be manufactured at a BSL-1 grade lab which brings down the cost of production and ensures that the cost of expanding production units. In comparison, Covaxin needs a Bio-Safety Level 3 lab to manufacture the jab.

The Plasmid DNA platform also allows generating new constructs quickly to deal with mutations in the virus, such as those already occurring

The science behind the jab: How does it work?

ZyCoV-D is a plasmid DNA vaccine which when injected produces the spike protein of the SARS-CoV-2 virus and elicits an immune response mediated by the cellular and humoral arms of the human immune system, which play a vital role in protection from disease as well as viral clearance.

In simpler words, it means that the vaccine is manufactured by creating a close enough copy of the virus' DNA sequence so that no harm or disease is caused, but the immune system response is triggered when the body encounters the real virus the next time.

Interim efficacy results

The vaccine has shown a primary efficacy of 66.6 percent for symptomatic RT-PCR positive cases in the interim analysis. Whereas, no moderate case of COVID-19 disease was observed in the vaccine beneficiaries post administration of the third dose suggesting 100% efficacy for moderate disease.

No severe cases or deaths due to COVID-19 occurred in the vaccine recipients after administration of the second dose of the vaccine.

However, its phase three trial data is not yet peer-reviewed.

The vaccine manufacturers also claimed that the vaccine's efficacy data were collected through India's largest clinical trial for a coronavirus vaccine so far. A study carried out in more than 50 clinical sites spread across the country and during the peak of the second wave of COVID-19 reaffirming the vaccine's efficacy against the new mutant strains especially the delta variant, Cadila Healthcare managing director Dr Patel said.

He also emphasised that the plasmid DNA platform is ideally suited for dealing with COVID-19 as it can be easily adapted to deal with mutations in the virus. Moreover, the DNA vaccines offer a number of potential advantages over traditional approaches that include stimulation of both B and T cell responses, improving the vaccine stability, says WHO.

Availability and pricing

The company said that it can be ready for rollout within 45 to 60 days of getting approval. The company plans to manufacture 10 to 12 crore doses annually in the early stages. However, the company did not give any hint on the expected price of the vaccine jab. It clarified that the price of the vaccine will be charged separately and the needle-free applicator will come at a separate cost. The company has, however, not yet decided if it will roll out the final product by clubbing the prices of the jab and the applicator.

"It is too early to comment on the pricing. That discussion is yet to happen. We will announce the price before the commercial launch of ZyCoV-D," Patel told a press conference. He said that so far up to Rs 500 crore has been invested in the development of the Zydus vaccine.

Originally posted here: https://ift.tt/3gmgn7Y

[mehuloffpage]

Dairy plant and equipment manufacturer in India

We “Saffron Machinery” have gained success in the Dairy plant and equipment manufacturer market by Manufacturing and Exporting a remarkable gamut of Dairy Machinery, Milk And Dairy Plant, Milk Storage Tank, Juice Processing Plant, Industrial Chiller, Ice-Cream Processing Machinery And Plant, CIP System, Bulk Milk Cooler, Mango Processing Plant, Fruit & Vegetable Processing Plant, Cold Room, etc. We are a well-known and reliable company at Ahmedabad (Gujarat, India). Our offered products are manufactured in compliance with the pre-defined industry norms and tested to ensure their flawlessness. Our Mission is To discover, deploy, develop and direct the available resources to enable them to demonstrate their optimum capacities to attain the highest possible level of productivity, profitability and customer satisfaction. Providing self employment in Rural India thereby improving their standard of living. We also Offering Industrial Erection Service to Our Client.

Incorporated in 2016 as Saffron Machinery with State-of-the-art Manufacturing unit of Dairy Equvipment, Food Processing Plants, Industrial Chillers And Amonia Chilling Plants,cold Rooms.

Highly skilled, dedicated, experienced work force.

[preengineeredsteel]

Faith PEB is a Prefabricated Building Company from Ahmedabad, Gujarat that was established 18 years ago. Our experience has earned us many faithful customers who have enjoyed our services without the chance of any complaints. Faith PEB has been supplying the newest and improved products in the market, making us the Top Prefab Structure Supplier in Jaipur.

Apart from these products, Faith PEB also manufactures prefabricated buildings, poultry sheds, industrial sheds and cold storage. Our reach has increased to 20 states of India, Rajasthan itself is home to many of our centres. Our network has helped us in becoming the top prefabricated structures manufacturer in India.

[ken-research-market-research]

India Logistics Market Outlook to 2024: Ken Research Buy Now The report titled “India Logistics Market Outlook to FY24–Driven by Government Infrastructure Push, New Age Logistics Startups and Technology Innovation…

[bharatref01]

Reliable Bulk Milk Cooler Manufacturer and Supplier Across India

This is going to be an engaging blog for those who are directly or indirectly connected with the dairy industry. This blog will further expand the knowledge of Dairy owners and senior professionals on bulk milk cooler and Bharat Refrigerations, one of the leading bulk milk cooler manufacturers in Ahmedabad, India. Moving forward, let's first understand the machine, the core subject of this blog.

What is a bulk milk cooler?  

The sophisticated machine is found at the milk collection center. Generally, when the milk is extracted from cow/ buffaloes, its temperature hovers around 37°C. In case this room is left at room temperature, the growth of microorganisms will take place. As a result, milk quality will deteriorate.        

The mechanized machine is designed to cool milk at 4°C. Thereby, maintaining its freshness, nutrients, and quality.      

Capacity

The machine is available in various capacities. Bharat Refrigerations’ bulk milk coolers are available from 250 liters to 10000 liters. The machine by one of the famous bulk milk cooler manufacturers is available in different shapes and sizes. Depending on your dairy collection’s requirements, you can choose the machine.        

Unique features of the machine          

A premium quality machine is identified with a few unique features. These include:    

Faster cooling owing to direct expansion

Robust design

Durable tank made of AISI 304 SS

Hermetically sealed compressor

Digital temperature controller

Occupies minimum space

Energy conscious

Designed to be user-friendly

As an owner of a dairy collection center, you deserve a quality-driven machine, that helps you to protect milk from deterioration. While purchasing the machine, match the salient features. Feel free to raise your queries, if any.  

Refrigeration Unit

How does the machine maintain a low temperature? Many of you might be thinking about this question. A refrigeration unit is attached to the machine to maintain the temperature.    

Here are some of the salient features of the unit:

Designed to work up to 45°C in Indian weather conditions

Minimum sound & easy to maintain

The refrigeration system designed in such a way that only 3°C temperature will increase in 12 hours after switching off the working unit at 2°C  

Insulation and other key features of the machine

Thickness 75mm

PUF Insulation

CFC free

Density 38 Kg/m ±2 kg

PUF pouring in the whole body by Imported Automatic Machine

Stirrer

Gear motor with auto control by timer i.e.:- Works for 20 minutes with an interval of 5 minutes

Facility to measure milk volume

How much milk is inside the tank? How to measure the milk? These are some of the obvious questions that strike the mind of owners when they place an order for a bulk milk cooler. You don’t have to worry too much. Most of the famous bulk milk cooler manufacturers provide dip-stick with a dip-stick chart to measure the quantity of milk in the tank.

Custom-designed bulk milk cooler

Many milk collection centers require a custom-designed product to fit their specific requirements. In this scenario, you can think about Bharat Refrigerations. Backed by the vast industry experience, India’s famous company has the competency to develop custom-designed machines.

Let’s collaborate for a mutually beneficial partnership  

Bharat Refrigerations is a wholly-owned subsidiary of Ice Make Refrigeration Ltd., an acclaimed name in Refrigeration Products and Equipment since 1993. Our excellence-driven total cold chain solutions comprise Cold Room & Storage Room, Transport Refrigeration, Commercial Refrigeration, Refrigerated Container, Bulk Milk Cooler, etc.  

If you are searching for glass door display fridges for your business, then end your search with Bharat Refrigerations! Companies' expertise in cold chain solutions has been helping businesses to meet their marketing business requirements.    

Let’s collaborate for a mutually beneficial partnership.

[coldmanposts]

Stay cool, stay safe with Coldman’s service of Cold Storage in Ahmedabad

Are you looking for Cold Storage Company in Ahmedabad? Does your companies deal with manufacturing or exporting of ice creams, Dairy Products, Eggs, Meat Products, Poultry Products, Fish and Shellfish, Fruits or Vegetables. Then you need to store your products in Cold Chain Companies to avoid the products to get rotten. Many companies who deal with these kinds of products face business loss every day because of improper storage of food. The suggested storage time of relies upon on what kind of food it is and the length of time and temperature the food is stored, before and after you purchase it. Properly storing food results in enhance nutritional quality, reduced waste from decay, decreased risk in foodborne disease when eaten, and fresher, better-tasting food. So choose Coldman who are best Cold Storage Company in Ahmedabad to avoid these businesses loses.

Why choose Coldman over other Cold Storage Company in Ahmedabad?

With our team who has complete industry knowledge about food storage and the freezing temperature of foods, our only goal is to maintain the quality of the food that no other Cold Storage Company in Ahmedabad.  For instant; Dry Foods we know that it needs to be kept dry and also at the ideal temperature range of 10°C to 15°C (50°F to 59°F). Where our storerooms are free from rodents and vermin and all wall, ceiling, and floor openings are sealed and protected to prevent access. Dairy products: We store in the refrigerator at temperatures of 2°C to 4°C (36° to 39°F). We also follow these basic guidelines: •           As the fat in dairy products has a habit to absorb strong odours from the storage environment.  To avoid this we have its own area in protective coverings. •           We keep refrigerator clean at all times. Produce food (fruits, vegetables, grains etc.): Such types of products we store at 2° to 4°C (36° to 39°F) to ensure freshness and to prevent rapid deterioration. Fresh Meats, Poultry, and Seafood: We know how expensive these products are in the market so we keep it under 4°C (39°F) or colder. We will make sure that carcass meats is unwrapped and hung so that air can circulate around them. And the cut meat such as steaks, chops, stewing meat, and ground meat is stored and kept covered on plastic or stainless steel trays at 2°C to 4°C (36°F to 39°F). We also provide Exclusive Pharma Zones for all medical products we store under strict conditions; requirements such as hygiene, temperature, traceability are paramount in this sector. We store medical products at temperature zones (Ambient (15–25ºC), Cold Room (2–8ºC), Freezers (minus 25–minus 15ºC) and Ultra-low Temperature Freezer Rooms (<minus 25ºC). we make sure the storage in a clean and protected environment. So choose best for your product and avoid all kinds of storage and weather damage by availing Coldman which is Chain Company in Ahmedabad services.

[blueiceindia]

Cold storage companies in India

Blue Ice India is a leading cold storage manufacturer company in Ahmedabad, India, we are able to provide sustainable solutions and services for your business and requirements.

Contact us at: 8866230337.

Visit us for more: blueiceindiaseo2022@gmail.com Visit site

[eagle-eyez]

https://ift.tt/eA8V8J

ZyCoV-D, a needle-free three-dose COVID-19 vaccine developed by Indian pharmaceutical firm Zydus Cadila received an emergency use license in India on Friday, after a government panel recommended the same to India's central drug authority.

The Ahmedabad-based pharma major had on 1 July applied for emergency use authorisation (EUA) with the Drug Controller General of India (DCGI) for the vaccine. The company said it has conducted the largest clinical trial for the vaccine in India in over 50 centres so far.

Why is this relevant?

ZyCoV-D is the world's first DNA vaccine against the novel coronavirus infection, developed by an Indian company and become the sixth vaccine that has been approved for use in the country after Serum Institute's Covishield, Bharat Biotech's Covaxin, Russia's Sputnik V and the US-made Moderna and Johnson and Johnson.

It is also the first vaccine candidate in India that has been found safe for use in children above the age of 12. Countries like US, France and Germany are already at various stages of providing vaccines for minors. In India, apart from ZyCoV-D, Bharat biotech's Covaxin is also under trial for use among the 2 to 18-year-old population.

Zydus Cadila, that already has anti-COVID treatments available in the market claimed to have conducted the largest clinical trial in India so far at over 50 centers and the participants included people between age group 12 and 18 years. The Covaxin trial includes 525 minor volunteers.

How is it different from other vaccines?

 ZyCoV-D is a three-dose vaccine, unlike Bharat Biotech's Covaxin and Serum Institute of India-manufactured Covishield jabs.

However, the company said it has also evaluated a two-dose regimen for ZyCoV-D vaccine using a 3-milligram dose per visit and the immunogenicity results had been found to be equivalent to the current three-dose regimen.

This will further help in reducing the full course duration of vaccination while maintaining the high safety profile of the vaccine in the future, the company added.

ZyCoV-D is touted to be a 'needle-free' vaccine.

It is an intradermal vaccine, which is applied using The PharmaJet needle-free system.  Needle-free injectors deliver the vaccine using a narrow stream of fluid to penetrate the skin and deliver the vaccine to the proper tissue depth. The company says this methodology can eliminate chances of needlestick injury and will also lead to a significant reduction in any kind of side effects. It will also help people suffering from trypanophobia, a common condition marked by an irrational fear of blood or needles. It's estimated that fear of needles affects up to 25 percent of adults.

ZyCoV-D is not very sensitive to temperature, unlike its competitors. The prescribed storage temperature is between 2 to 8 degrees centigrade but has shown good stability at temperatures of 25 degrees centigrade as well for at least three months.

The thermostability of the vaccine will help in easy transportation and storage of the vaccine and reduce any cold chain breakdown challenges leading to vaccine wastage.

The plasmid DNA platform provides ease of manufacturing with minimal biosafety requirements.

It can be manufactured at a BSL-1 grade lab which brings down the cost of production and ensures that the cost of expanding production units. In comparison, Covaxin needs a Bio-Safety Level 3 lab to manufacture the jab.

The Plasmid DNA platform also allows generating new constructs quickly to deal with mutations in the virus, such as those already occurring

The science behind the jab: How does it work?

ZyCoV-D is a plasmid DNA vaccine which when injected produces the spike protein of the SARS-CoV-2 virus and elicits an immune response mediated by the cellular and humoral arms of the human immune system, which play a vital role in protection from disease as well as viral clearance.

In simpler words, it means that the vaccine is manufactured by creating a close enough copy of the virus' DNA sequence so that no harm or disease is caused, but the immune system response is triggered when the body encounters the real virus the next time.

Interim efficacy results

The vaccine has shown a primary efficacy of 66.6 percent for symptomatic RT-PCR positive cases in the interim analysis. Whereas, no moderate case of COVID-19 disease was observed in the vaccine beneficiaries post administration of the third dose suggesting 100% efficacy for moderate disease.

No severe cases or deaths due to COVID-19 occurred in the vaccine recipients after administration of the second dose of the vaccine.

However, its phase three trial data is not yet peer-reviewed.

The vaccine manufacturers also claimed that the vaccine's efficacy data were collected through India's largest clinical trial for a coronavirus vaccine so far. A study carried out in more than 50 clinical sites spread across the country and during the peak of the second wave of COVID-19 reaffirming the vaccine's efficacy against the new mutant strains especially the delta variant, Cadila Healthcare managing director Dr Patel said.

He also emphasised that the plasmid DNA platform is ideally suited for dealing with COVID-19 as it can be easily adapted to deal with mutations in the virus. Moreover, the DNA vaccines offer a number of potential advantages over traditional approaches that include stimulation of both B and T cell responses, improving the vaccine stability, says WHO.

Availability and pricing

The company said that it can be ready for rollout within 45 to 60 days of getting approval. The company plans to manufacture 10 to 12 crore doses annually in the early stages. However, the company did not give any hint on the expected price of the vaccine jab. It clarified that the price of the vaccine will be charged separately and the needle-free applicator will come at a separate cost. The company has, however, not yet decided if it will roll out the final product by clubbing the prices of the jab and the applicator.

"It is too early to comment on the pricing. That discussion is yet to happen. We will announce the price before the commercial launch of ZyCoV-D," Patel told a press conference. He said that so far up to Rs 500 crore has been invested in the development of the Zydus vaccine.

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