#Cell Isolation/Separation Market

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Cell Isolation/Cell Separation Market — Forecast(2024–2030)

Cell Isolation/Cell Separation Market — Forecast(2024–2030)

Cell Isolation/Cell Separation Market Overview

Cell Isolation/Cell Separation Market Report Coverage

The report: “Cell Isolation/Cell Separation Market Forecast (2020–2025)”, by Industry ARC, covers an in-depth analysis of the following segments of the Cell Isolation/Cell Separation Market.

By Product Type: Consumables and Instruments.

By Cell: Human Cell and Animal Cell.

By Technique: Filtration Based Cell Isolation, Centrifugation Based Cell Isolation and Surface Maker Based Cell Isolation.

By Application: Stem Cell Research, Cancer Research, Biomolecule Research, Vitro Diagnostics, Tissue Regeneration, Others.

By Geography: North America, Asia-Pacific, Europe, Rest of World (RoW).

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Key Takeaways

Geographically, North America Cell Isolation/Cell Separation Market accounted for the highest revenue share in 2019 and it is poised to dominate during the forecast period 2020–2025 owing to the high demand.

The increase in the technology and awareness among customers is likely to aid in the market growth of Cell Isolation/Cell Separation Market.

Detailed analysis on the Strength, Weakness and Opportunities of the prominent players operating in the market will be provided in the Cell Isolation/Cell Separation Market report.

The increase in the number of chronic diseases and increase in the demand for laboratory automation are creating higher opportunities for the growth of market for the forecast period 2020–2025.

By Service Type- Segment Analysis Based on the Service Type, the Repair and Maintenance segment held the largest share in 2019 owing to the factors such as rapid increase in the use of laboratory equipment for research activities and increase in the investment by the public and the private companies. Calibration segment is estimated to be the fastest growing segment during the forecast period 2020–2025. The growth in this segment is owing to the factors such as growing need for accurate and precise information, growing consciousness among customers and the government regulations.

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By End User- Segment Analysis

Based on the End User, the Clinical and Diagnostic Laboratories segment held the largest share in 2019 owing to the factors such as rapid increase in the research in drug discovery by the major companies, rapid increase in the number of diseases and growing awareness regarding health. Pharmaceutical and Biotechnological Companies segment is estimated to be the fastest growing segment owing to the factors such as increase in the demand for long-term treatment for chronic diseases, growing healthcare financial products and increase in the demand for generics market.

By Geography — Segment Analysis Based on the Geography, North America held the largest share in 2019. The growth in this segment is owing to the factors such as advancements in technology, rapid growth in the healthcare infrastructure and government policies supporting the developments in healthcare. Asia-Pacific is estimated to be the fastest growing segment owing to the factors such, as rapid increase in the import of laboratory equipment, investment by the major companies in the developing nations and growing research in pharmaceutical companies.

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Cell Isolation/Cell Separation Market Drivers

Rapid increase in the research activities in the pharmaceutical and biotechnological industries.

The increase in the research activities in the pharmaceutical and biotechnological industries owing to rapid increase in the number of diseases, well developed infrastructures and advancements in technology is estimated to enhance the growth of Cell Isolation/Cell Separation Market. The increase in the demand for laboratory automation is also estimated to enhance the growth of Cell Isolation/Cell Separation Market.

Government’s policies to enhance biomedical research activities.

There is a rapid increase in the initiatives and policies by the governments towards biomedical research activities owing to growing awareness among customers increase in the number of aging population and growing prevalence of chronic diseases. This led to rapid increase in the growth of Cell Isolation/Cell Separation Market. Investments in the biotechnology sector and improvement in the healthcare infrastructure is also estimated to enhance the growth of the Cell Isolation/Cell Separation Market.

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Cell Isolation/Cell Separation Market Challenges

The shift from lab-based diagnosis to home-based testing and high cost associated with the service contracts and raw material.

The shift from lab-based diagnosis to home-based testing owing to increase in the awareness among customers, decreasing the chances of complications and advancements in technology is estimated to reduce the growth of the Cell Isolation/Cell Separation Market. High costs associated with the service contracts and raw material is also said to reduce the growth of the Cell Isolation/Cell Separation Market.

Cell Isolation/Cell Separation Market Industry outlook: Product launches, mergers and acquisitions, joint ventures, and geographical expansions are key strategies adopted by players in the Cell Isolation/Cell Separation Market. Key companies of this market are Agilent Technologies, Danaher Corporation, Pace Analytical Services, Thermo Fisher Scientific Inc, PerkinElmer Inc, Waters Corporation, Eppendorf AG, Siemens Healthineers, Abbott Laboratories, Bio-Rad Laboratories Inc among others.

Acquisitions/Product Launches:

In 2020, Agilent Technologies has launched CrossLab Connect Services for Lab-wide Asset Monitoring, which is an advanced service for laboratories seeking increased visibility and control over operations.

In 2020, Waters Corporation has launched the Waters ARC HPLC System to help laboratories meet quality and production targets and for routine testing in the pharmaceutical, food, academic and materials market.

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[soumyafwr]

https://chatterchat.com/read-blog/76202_global-cell-isolation-or-cell-separation-market-size-overview-key-players-and-fo.html

Cell Isolation or Cell Separation Market 

[vibratingskull]

Yandere Thrawn x F!reader chapter 12

Yandere AU - 2 - 3 - 4 - 5 - 6 - 7 - 8 - 9 - 10 - 11

Tags : Yandere behaviors (duh), gaslighting, funerals

“It is with a heavy heart that we have to say goodbye to two of our esteemed colleagues.” Thrawn ceremoniously says, in front of two coffins in the grand hangar of the Chimaera, “Those two women accomplished their duty with diligence, uprightness, and more than anything, with an undying loyalty to the Empire. We can only strive to do as well as them.” He concludes. 

He advances and leaves a single rose on each of the coffins. They are both empty, but the gathering behind him doesn’t know it. One coffin for the Captain promptly expelled in the cold and never-ending night of the universe and one for you, carefully hidden in his suite, paralyzed and powerless. 

All your colleagues are here for a last homage to two women who strived to accomplish their duties each day with righteousness. Only Thrawn knows the truth about you two. “Farewell, Ma’ams.” He finishes and everyone bows to your coffins. 

The coffins are taken to the furnace of the Chimaera and the gathering spreads in little groups, discussing about you or what this ceremony inspired them. Thrawn sneakily steals a third rose in the bouquets displayed and walks calmly among the cells, accepting greetings and congratulations as he walks by before joining the little group of officers that beat you up. The group is strangely silent contrary to all the others, still uneasy, like they could be discovered now. 

“Gentlemen, Ladies. My congratulations.” He says, his hard gaze traveling from one face to the other wincing with more or less discomfort. “You have executed your last mission with brio. You can be proud of yourself.” 

But they aren’t. In their eyes they killed two of their colleagues and nothing will be able to take that weight off their shoulders. Not even Thrawn. That is well, he doesn’t care if nightmares prevent them from sleeping at night. “I know this is little consolation, but you have my gratitude.”, “Thank you, Grand Admiral.” one of them mutters. “Just know you have done the right thing,” he assures them before approaching Faro who stayed in the doorway. 

“You did not want to see the ceremony from a better point of view?” He asks, curious. “No.” She responds with a somber tone, “I do not deserve it. I was a bad friend to (F/n)...”, “How so?”, “I turned my back on her when she needed my help the most. I did not believe her when she proclaimed her innocence to me. This is unforgivable.” She lowers her head, clearly disappointed in herself. “The false proves were convincing. I, myself, had some difficulty separating facts from fiction.” He consoles her, but she hears none of it. “Still! I should have known, I should have believed her no matter what. And now I can’t even say sorry.”, “I am sure Lieutenant Commander (f/n) would not hold it against you. Raise your head, Commodore. Do not let it hold you down, I need you ready and alert.”, “Yes, Grand Admiral.” she acquiesces but her heart isn’t into it. “Do not be too hard on yourself. You have done what was expected of a Commodore in your hard situation. You can be proud of yourself.”, “Thank you, Grand Admiral. What are you going to do with that rose?” She tilts her head. “This little thing? My suite could use some rose fragrance.” He answers enigmatically. If Karyn didn’t know him well she would have thought he sadistically smiled. But she does know him well, he isn’t like that! 

Thrawn walks silently in the corridors, inhaling the scent of the red flower pressed against his nose. He will give you that rose. He will command you a proper large bouquet later, for now, he will offer you that single flower, red like his heart beating for you.  

You gave him so much pleasure yesterday you deserve a gorgeous bouquet! He also started looking into the housing market and he found some properties on some isolated planets, some charming little cottages away from towns and villages. With a big garden for you to lazily bask in the sun, to do some gardening if you so wish, but mostly for his children to play. He can’t wait to meet them, to see them running around you two and doing cartwheels in the green grass.  

He wants a big tree to install a swing for them to play, a pool for you to relax on a deck chair to read, and a patio to eat under the sun with the family when the good days finally arrive. He wants a large family. 

He wants children with you! He wants to see you round and swollen with his babies. 

He keeps fantasizing about his future domestic life when he reaches his suite. He immediately heads towards his bedroom where you obediently await his return every day. “Hello, Cha’cah.” He greets you with a smile. 

You are hidden under the covers, recoiling in a ball. Still and mute. If he couldn’t read your heat signals he could think you were dead. He sits on the edge of the bed, laying his hand on your hidden shoulder and gently squeezes it, “Stop hiding, Ch’acah. Let me see your face.”  

As you refuse to move he grips the cover’s hem and pulls on it, revealing your face to his eyes. How beautiful you are, all pouty like that! You grumble and immediately try to hide your face again. 

You cannot face him. 

Not after what happened yesterday. You are still in shock. 

He chuckles and pulls more on the cover, “Come on, now. Do you intend to deprive me of your ravishing face?” He demands and immediately leans in to kiss your cheek. You do not respond to the kiss, forcing your eyes shut, slightly trembling.“I have a little present for you.” He takes a little lick at your cheek and takes the rose off behind his back. 

You remain mute and eyes shut. He brushes the rose under your nose making you sneeze and finally react. You hesitantly take the rose between your hands while he kisses your temple. 

He is so happy! You’ve made such progress in your relationship! You desire him as much as he desires you now, craving each other's presence. He wants to hug you all day long, having you on his lap while he works at his desk, embracing you all night! He wants the complete page! The real deal! 

You surely spend the whole day awaiting his return desperately counting the hours until he returns in your arms. Your pa ack ssionate night must plague your mind and entice you to do it again, but you’re so shy you surely won’t try anything 

He can’t wait to hold you tight tonight again. And surely you too! 

But he knows he still has to tame you, he is only midway through his goal. He needs a lot more tenderness and sweet touches for you to be fully comfortable and open. 

 He knows it. 

But he is prepared for it. 

You?  

You are confused, out of your mind, dwelling on the same questions, the same interrogations spinning in your head non-stop. 

You trusted him, you looked up to him, felt safe with him… You placed your life between his hands! 

You spend all day eyes hypnotized by the bay; looking at shiny stars, dissociating completely, mind bubbling and bursting out of your skull.  

His fingers come gripping your chin to spin your face towards his burning red gaze. “Let me look at you, Ch’acah. Let me admire your gorgeous face, I miss it dearly all day long.” He demands, between a plea and an order, “How I love to appreciate it in detail. Your expression yesterday night was just so... Exquisite.” He praises, his red eyes shining brighter, “If only you knew how long I desired it.” 

You gulp, lowering your gaze before him. 

Was... Was it all your fault? If you kept your mouth shut and didn’t speak his name, would it have happened still? 

“Why do you not look me in the eyes, my sweet? I so long for your gaze on me.” He asks, his thumb coming to caress your lower lips, parting them lightly. You gasp, at a loss for words. What to respond? How will he react? Will he kiss you? Will he become violent? Will he just shrug it off? Will he slap you? Will he leave you alone and untouched? 

Far away from your confusion and trouble, Thrawn observes your face, idolizing your features, adoring your dazed expression. How are you so effortlessly beautiful? He wonders, simply amazed. And your voice... Truly mesmerizing. 

“I... I just...” You start, raising your eyes to meet his to immediately get a flashback of the dark and heavy gaze he had last night. Absolutely terrifying. He looked like a carnivore that spotted a bleeding prey. 

And he acted like one... 

How much of what happened is actually your fault? How much responsibility do you hold? Clearly, you shouldn’t have masturbated in your Grand Admiral’s bed, but does it legitimize his actions? 

Surely not... Or maybe... Yes? 

“You were so captivating yesterday.” He continues, “Touching yourself so shamelessly in my bed like that. I could have admired you for entire hours. And when you whispered my name... So lowly, so... lecherously...” He deeply inhales like he is fighting back something inside of him and buries his head in the crook of your neck, making you jolt and tremble, on edge, “I could not believe what I heard. You, desiring me? My heart warmed up in joy. If only you knew how much it meant to me.”  

You... Desiring... Him? It’s true you were masturbating to him, but... Did that give him any right?  

He lazily kisses your neck, laying on you, trapping you under his weight. He gives sweet, little licks, making you start and tremble between his large hands. He cannot help but chuckle, it is so endearing how reactive and sensitive you are. You are simply so sweet to him. So adorable and easy to adore. One of his hands traces its way up your arm to trap your valid hand and intertwines your fingers together, holding it firmly. 

 “You are so silent, Ch’acah. I miss your melodious voice, will you not sing a single word to my ears?” He demands, kissing the scar on your neck, letting the sweet memory replay in his mind. “I... I am... not sure I-” you start before he cuts you entirely, “Of course, Ch’acah, of course you are confused. It is a large step that we took together, it is a true leap of faith. But together we can make it work.” 

You can clearly hear the satisfied smile in his voice as he pecks your nape tenderly, but you are not as sure as him. “It’s not... It’s not what I am trying to-” You moan sharply, hissing as he suddenly sucks on your skin. You squirm under his large and tall body, trying to get out of under him, but your two casts prevent you from moving properly, and either way, his strength keeps you firmly in place under him. He raises his head to look at you with a foggy gaze, heavy with dark desires.  

“It is all right, ch’eo ch’acah.” he murmurs darkly, “We will figure it out. I will satisfy you like you never were before.” And before you can contradict him he captures your lips in a demanding kiss. He devours your mouth, robbing you of all your air. You refrain a yelp and bite his lip til he bleeds to make him stop. He parts with you with a grin, licking his bleeding lip with brighter eyes, “Interesting...” He takes note, strangely pleased by your reaction. 

You try to look enraged, frowning your brows and baring your teeth to deter him, to make him realize he should back down. But instead, you see even more hunger brewing in his predatory gaze, like something switched in his mind. A single drop if his blood falls on the corner or your lips and he spreads it on your lips with his thumb, adorning your mouth with rich, deep red. 

“I love your energy, Ch’acah.” He says with an increasingly deranged gaze, but his voice as still and calm as it always was, “Can you keep it up all night?” He asks, hope flourishing in his dry heart. You look at him shocked and at loss for words you only can gasp at his outrageous demand.  

He visibly softens at your reaction, caressing your cheek tenderly. “It is all right, ch’eo ch’acah. We can take it slow.” He says lowly, brushing his nose in the crook of your neck, “There is so many things I would like for us to do, so many things I would like to share with you.” 

You do not know it yet but you love him too, he knows it, but you are still confused. He will give you more time. 

At least until he cannot repress it anymore... 

“I just want you to know you filled my heart with joy yesterday.” He confesses, “Knowing we reciprocate feelings... This is truly a blessing by the Warrior.” He tenderly looks into your eyes, holding your cheek with his warm large palm, preventing you from escaping him. 

Are you reciprocating his feelings? Wait, what feeling are we talking about? Lust? Love? Hate?  

“Thrawn.” You manage to say with a firmer voice, catching his attention, “I think you are... misunderstanding the situation. You are dear to me, but... I don’t think I wanted-” He tilts his head, squinting a bit, his gaze slowly switching to dark lust to...Warning and threats, shutting you up. 

You feel yourself starting to tremble under his black gaze. 

“Ch’acah... Oh Ch’acah.” He chants, a grin flourishing on his face, “You do not make any sense, ch’eo Ch’acah.” He darkly chuckles at your discomfited expression, “You called for me, and I simply responded. I would never have laid a hand on you without you desiring it, I think you are mixing responsibilities here. ” He lowers his head to brush his nose with yours, a purr raising in his throat,  

“Thrawn...” you try again. He shushes you, putting his bumpy forehead against yours, looking deep into your human eyes, “You are still confused. Your consciousness is trying to convince you you did not want it because you lost your former lover tragically. It is trying to protect itself from pain and loss.” His thumb caresses your cheek as he speaks, hypnotizing you with his red eyes. 

Is... Is it true? Thrawn never lied to you until now and you cannot imagine him truly assaulting a woman... Could it be the truth? 

But why are you feeling so dirty and disgusted with yourself? 

“It is a perfectly natural reaction, it is your survival instinct trying to protect your mental and physical integrity. It is extremely common in fields bordering on death daily. I have witnessed it plenty of times.” He outrageously lies to you, “Trauma can take many forms, denying oneself a chance with love is pretty common after a loss.” 

“But I felt so gross after it...” you feel tears rising behind your eyes, his touch burning your skin off. “How can I even know you’re right?” Your voice cracks. 

You didn’t let yourself cry in his presence, and while he was away your mind was so full and blank at the same time no tears reached your eyes, but now they threaten to spill all over. 

“It is quite simple, ch’eo Ch’acah.” His smile dripping with false sweetness, “If you cummed it means you enjoyed yourself and desired it. This is not something easy to fake, is it not? Did you cum?” He plays cruelly with you, forcing you to admit your greatest shame. 

That you came under his assault. 

“I... I am not sure? I-I just-” He licks your cheek with the flat of his tongue, making you whine and gulp, “You cummed really hard Ch’eoh Ch’acah, like I promised you would. There is your proof my sweet.” He muses, thoroughly amused by the situation. 

It is so sweet of you to try to understand the situation while reconciling with the sweet persona he offered you all this time. Your broken mind cannot compute the fact that he of all people did that to you, that you must have provoked the situation in some way. That your gentlemanly and sweet Grand Admiral could never assault you. 

And he fully intents to take advantage of this vulnerability. 

“Discard those negative sentiments and doubts, your body knows what it wants and what is good for it. The mind is more tricky to appease once wounded, it will take you time to heal, but I know how to help you mend quicker.”  

“You do?” you ask with a voice where hope and fear mix. 

“We should simply do it again.” He drops the bomb with a deliciously satisfied smile. You open your eyes wide open, incredulous, “Excuse me?” You ask in a white voice. “It is exposure therapy, Ch’acah. Making you confront your fear will help you.”, “I am not sure this is for me.”, Thrawn tilts his head like he didn’t understood your reaction, “I only want what is best for you, (Y/n). You know that right?” 

“I... Think” you gulp. 

“I only want to help you.” He insists, “Do you believe I could do anything to hurt you? Me? Your Ch’acah?” 

Your mind froze. The memories of yesterday night fighting the memories of your sweet polite friend. Thrawn, always so nice and supportive, your Ch’acah who forgave your stab in his back. The one you wounded in his flesh. Is it possible? That you completely misconstructed that situation and he is telling the truth? You knew each other for years, Eli and Karyn trust him. He never raised his hand on anyone. He is an upright man, a moral person you blindly trusted. 

Your brain cannot reconcile those two very real aspects of him, one must come up on top. He simply awaits which one, ready to jump into action and modify his plans in split second if you realize the monster he truly is. 

“...No...” you finally let out, tears flowing on your face. 

He smiles carnivorously, congratulating himself. Those long days playing the good loyal friend all cumulated to this moment. Before the impossible dilemma he presented you, your brain chose to hide the truth, too ugly to witness. That he is such a monster, that he assaulted you and took advantage of you in more ways than one... Before the hideous reality, your mind buries its head in the sand and convinces you all of it was just a bad dream, a misunderstanding, that your tormentor is still your nice friend, only wanting the best for you. 

“No, I cannot believe that...” You broke down completely. 

“Shhhhhhhhh... It is good, my sweet.” He caresses your hair gently, brushing your noses together, “I do not hold it against you. In confusion you are ready to believe anything. Even that your most loyal support could do anything against you.” You sob, big tears rolling off your eyes, you gasp for air “I... I never wanted to think that about you!” You gulp, “But I was so confused and afraid. Thrawn I am so sorry!” 

“No need to be, Ch’eo Ch’acah. I forgive you.” He holds you tight, hugging you, shielding your body with his massive one. “You are grieving and in pain. Your disarray is understandable. You may not worry, I am not holding it against you.” He murmurs into your ear with a sickly sweet tone. 

Oh, sweet thing... So sweet and fragile little darling... How blissful he feels at this very instant. You, presenting your excuses to him, your torturer, craving a rational explanation that aligns with your views of the world so much you are willing to believe your executioner. You are just a sweet, little bird with broken wings. It is easier to believe you hold responsibilities and lay against yourself than face the reality that your best friend and benefactor assaulted you. 

Absolutely fascinating how one’s mind is ready to believe anything rather than a painful and uncomfortable truth. But right now he is incredibly grateful for it. He ravished you and got out of it dirt free. 

No.  

He got out of it as a saint! As the one who tries to heal you, working against your dysfunctioning mind and consciousness. How could you be mad at him? Him who forgave you every transgressions and kept you under his wing to propel your career? 

At least in your eyes... 

This gamble was high risk, he is deeply, viscerally aware of it, but also high reward and he hit the jackpot! Now you are his, and his alone. To toy and play with all he wants. 

He refrains from whispering “I love you.” in your ear, you had enough earth-shattering info for the day. He will whisper it endlessly to you later when you are less on edge. 

He buries his nose in your hair and deeply inhale your scent. You still smell like sex. Nothing surprising, he left you as is yesterday, in your soiled clothes, drenched in your essences and musk. As much because he wanted to smell his victory on your body for one more day than because he felt you would have clawed his face if he approached you. He spend the whole night in his office working to leave you alone with your fear and doubts, letting them fester in your mind to destabilize you mentally. 

And it was the right call... 

He stands back up on his feet, wrapping his arms around you to lift you up bridal style, “You are soiled, ch’eo Ch’acah.” He lets you know, forcing you to lower your gaze in embarrassment and defeat “Let me clean you up thoroughly, you will feel so much better after...” 

@bluechiss @blueninjablade3 @al-astakbar @thrawnspetgoose @readinglistfics @twilekchiss@pencil_urchin @ineedazeezee @dance-like-russia-isnt-watching  @obbicrystaleo @germie2037 @leo4242564 @davesrightshoe @holylonelyponyeatingmacaroni 

[pascaloverx]

Invisible Bonds: The Power of Destiny

Author's Note: This fanfic contains possible strong language and explores themes of unconventional love. The relationship between the protagonists will be handled with sensitivity, without explicit scenes. If there are explicit scenes, readers will be warned. This fanfic focuses on the reader's relationship with Jungkook and Taehyung, separately.

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Chapter Nine

The pain in your chest reflected the feeling you've been keeping inside all this time. I mean it's been practically a week since you kissed your best friend and ended a relationship non-existent with your soulmate. To say the first few days after your big argument with Jungkook were easy would be hypocritical.

In fact, you completely isolated yourself, afraid of what would happen if you saw each other. You felt embarrassed to face your friends, realizing that you had become the talk of the moment. You also hesitated to talk to Taehyung about what happened the last time you two were alone. All you were able to do was fall into a routine. Go to work, go to the market and come home. Every day the same thing without interacting with anyone. Are you careful not to go out to work At the same time that Jungkook is leaving, you avoid going to the market near where you live. You talk to your friends on the phone but refuse to go to their house. At this point you know what they will want to talk to you about. And until today, you've felt like you were handling everything well, even though it tugs at your heart being separated from Jungkook and avoiding Taehyung.

"You look terrible, Y/N." You heard a male voice approaching just as you were entering your apartment after a tiring day of work.You were about to ignore it, as you've been ignoring everything related to Jungkook, but then you dared to look ahead. Those dark eyes were incredibly teary, as if he had cried recently. That's when you remembered shedding tears on your way home, realizing the connection you both shared.

"Good evening, Mr. Jeon Jungkook. Thank you for the feedback. If you'll excuse me..." you say, trying to avoid looking at him again. Your hand trembles slightly from nervousness. The truth is, as Jungkook hasn't ended the connection between you two, every cell in your body wants to be with him. Close to him.

"I would love to do that with you but unfortunately I just wanted to let you know that I'm going to start the process of ending our connection. I know this will hurt on both sides of the call so I suggest..."Jungkook speaks with a firmness that almost hurts you. Doesn't he feel pain at the thought of not being your soulmate?

"I dismiss your suggestions. I just sincerely hope you suffer through this." You say getting closer to Jungkook. You're so angry that you don't even notice how close you are to him.

"I don't believe anything you're saying. Your mouth says one thing and your eyes say another." Jungkook speaks, increasing the proximity of the two of you. And for some reason you felt good, your heart he seemed to have calmed down with your proximity.

"Believe what you want. Soon you'll do us a favor and separate us forever. Each one going their own way." You say looking at Jungkook who immediately kisses you. Such a surprising kiss that you don't even know how to react. You only respond to the kiss because you don't have the strength to fight it.

"Believe it or not, I'm doing what's best for both of us." Jungkook says as soon as he breaks the kiss. You don't even have time to say anything, he just goes away. You then start to feel tears running down your face. And an immeasurable pain inside you. You sit in front of your apartment letting the tears come out, convincing yourself that everything you feel for Jungkook will disappear. You take your cell phone from your bag and dial the number of the person you usually call when you need support.

"Can you come stay with me?" You talk on the phone, figuring that if you're going to go through all this pain, you're going to need someone by your side.

"There's no other place in the world I'd rather go to. I'll be there in about ten minutes." Taehyung speaks on the other end of the line. You then turn off your cell phone and wait for him to arrive. Knowing that this is the end of your brief connection with Jungkook.

[reneeofthestars]

Stand Up Together

I’m so excited to finally share the short story I wrote for @legacy-rebelsfanzine​ ! 

I love Star Wars Rebels, and I’m honored to have gotten to work on this wonderful zine! 

Read on AO3     Words:1,427

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It was a dream Ephraim Bridger had grown familiar with.

He would open his eyes and find himself standing amid the grasslands of Lothal, the landscape dotted with rock formations, the sky warm with orange and gold as the sun set.

Laughter just ahead would draw his attention, and there was his son, having lured yet another loth-cat out of its nest to play. At his side, Mira took his hand in hers and leaned into him, standing on her toes to kiss him. Ephraim would wrap his arms around her, closing his eyes as he took in the peace around him, holding onto the dream as long as he could.

This time, though, the dream changed.

Ezra’s sudden silence broke him out of his reverie. When Ephraim found him again, Ezra was far ahead, his wild blue-black hair barely visible above the tall grasses. His son stood stock-still, transfixed by the sudden appearance of a white loth-wolf that towered over him.

The boy didn’t look frightened; he stared in awe at the creature, even as Ephraim’s heart leapt to his throat and he pulled Mira along, sprinting towards Ezra. The loth-wolf watched as Ephraim ran, but the creature made no move to attack. Instead, it laid down and waited patiently, yellow eyes studying him. The loth-cat Ezra had been playing with scrambled up the wolf’s back, coming to rest on its head.

Ephraim called out for Ezra, and the boy turned to him. His face split into a wide grin, showing his missing front teeth. “It’s okay, daddy!” he called, patting the loth-wolf’s leg. “It’s time to stand up!”

Ephraim woke in his cell, still reaching out for Ezra.

*

“You’re quiet,” Mira murmured as she sat beside him to eat. The pristine Imperial detainment center encased them, as devoid of expression and as militant as the stormtroopers that guarded it. The morning broadcast toting the Empire’s propaganda droned on in the background of the mess hall, masking their quiet conversation. Ephraim had learned to tune the noise out.

“I had a dream.”

She smiled knowingly, age lines crinkling around her eyes. “Ezra?”

He nodded as his throat tightened. “He told me it’s time to stand up.”

Mira choked on a laugh, then quickly sobered as a trooper guarding the door turned sharply to look at her. Once the trooper resumed his stance, she lowered her voice while picking at her rations. “I hope he remembers that.”

“I think we told him often enough.”

“He was so little. Young, I mean.” She paused thoughtfully. “Do you think he’s taking after you or me, height-wise?”

“We’ll find out, one day.”

She rested her head briefly on his shoulder, her headwrap secured around her hair. That had been one decency the Empire allowed her. The other had been allowing him to keep his beard, instead of being clean-shaven. He briefly kissed her forehead. The greatest mercy the Empire had shown was allowing them to stay together.

Of course, any time the officers thought Ephraim and Mira were speaking too loudly, too pointedly about the flaws of the Empire, or were found encouraging an ever-growing group of prisoners, they were threatened. Threatened with labor, with death, with separation. They had been punished in the last seven years of their captivity, but so far, no extreme penalty had befallen them.

Seven years. Had it really been that long?

He held his cup tightly, watching as droplets fell from the rim where they’d sloshed. Not a day went by that he didn’t think about his son. His little boy was fifteen now. How old would he be when Ephraim finally got to see him again?  

Mira’s voice pulled him from his isolation. “Do you remember,” she said, trying not to laugh, “when he turned on the broadcast when we’d gone to the market?”

Ephraim ducked his head to hide his smile from the troopers. “And announced to anyone still tuned-in that he’d drawn a picture of a Jedi in a ship fighting back against the Empire.”

“I didn’t know you could run that fast. You reached him minutes before I made it back.”

“I swear, I locked the hatch to the room.”

“I know – I watched you do it. He just had a knack for getting into places he wasn’t supposed to be.”

“Like the roof.”

“Oh!” Mira put a hand to her chest, as though the memory still made her heart flutter in worry. “If Tseebo hadn’t climbed up after him, I don’t know what I would have done!”

“I would have come over myself to get him, if you’d needed me to,” a gruff voice broke in.

A broad-shouldered man with sun-tanned skin and a white beard set his tray down with a huff across from them. A dark purple circle ringed his eye.

“Ryder.” Mira raised a hand to examine the bruise. “What happened?”

The former governor of Lothal waved her away. “I’m alright, Mira. Got into a little scuffle with the guards, that’s all.”

“What? Why?”

After making sure none of the troopers were nearby, Ryder pitched his voice low. “I caused a distraction for two of the new inmates. The Bothan and the Mon Cal? They were able to hack an outlying terminal and get a map of the facility.”

Leaning closer, Ephraim asked, “Are they planning something?”

Ryder shrugged. “Seems like they want to, but they don’t have any ideas past getting a layout of the place. Figured it was a good opportunity to get –”

The speakers buzzed; the words of the calm Imperial broadcast cut off in a burst of static. Frowning, Ephraim glanced around. Others had noticed as well; guards and prisoners alike looked to the speakers in surprise.

The static continued, and he heard an officer call over her comm to check the holonet signal. After a few moments, the interference ceased, and a strangely young male voice reverberated around the mess hall.

“We have been called criminals, but we are not. We are rebels, fighting for the people, fighting for you. I'm not that old, but I remember a time when things were better on Lothal.”

Ephraim’s heart stopped. Mira seized his wrist, her knuckles white.

“Maybe not great, but never like this. See what the Empire has done to your lives, your families, and your freedom? It's only gonna get worse…unless we stand up and fight back.”

An officer was yelling orders to cut the connection, but there was nothing they could do; the Imperial broadcasts were hardwired to play consistently throughout the prison. And now every prisoner stared at one another – dissenters, fighters, activists, and so many others – and Ephraim saw a spark in their eyes as the transmission continued.

“It won't be easy. There will be loss and sacrifice. But we can't back down just because we're afraid. That's when we need to stand the tallest. That's what my parents taught me. That's what my new family helped me remember.

“Stand up together. Because that's when we're strongest—as one!”

Another burst of static crackled over the speakers, followed by a ringing silence.

Tears filled Ephraim’s eyes, and he let them fall, his heart swelling with so many emotions he thought it might burst. Relief, pride, concern, love, all swirled into a bubble that finally broke through as a sob.

Mira’s hands were shaking as she gripped him tightly. “He’s alright,” she whispered against his cheek. “Ezra’s alright.”

“Ezra?” Ryder frowned. “You think that was him?”

“She’s right,” Ephraim murmured, pulling her close. His tears stained her headwrap, but it didn’t matter. “The way he spoke, the phrases he used – it’s the same things we’d say in our broadcasts.”

“His voice sounds just like you when we were younger.” Mira smiled through her own tears. “He’s out there, fighting for the free galaxy we wanted for him. And with a family – Ephraim, someone’s looking out for him.”

The buzzer sounded, alerting all detainees that they were to return to their cells. The stormtroopers seemed rattled; they snapped at the closest prisoners to move faster, grips tight on their blasters, helmets swiveling as they scanned the mess hall.

Ephraim stood, but a lightness in his chest made him pause. He met Mira’s eyes; determination danced in her gaze, and she nodded once. Their son was out there, standing up for others, standing against the Empire. And it was high time Ephraim and Mira joined him.

Ryder glanced between them. “I know that look,” he muttered uneasily.

Ephraim clapped him on the shoulder. “Stand tall, Ryder. It’s time to act.” 

*

[queer-starwars-bracket]

Queer Star Wars Characters (Round 4): General Bracket Match 3

Chelli Lona Aphra | Identity: lesbian | Media: Star Wars Comics

Oh Aphra, where to begin. Honestly the best way I can describe her is that she’s Star Wars’ Vriska. She’s a “rogue archeologist” and in marketing material sometimes compared to Indiana Jones, but the only similarity is that she can feature in the same wacky stories about retrieving artifacts except with none of the mismatch between modern ideas about archeology and repatriation and Indy being the hero, because she specifically isn’t. She was originally created for the 2015 Darth Vader comic series, recruited to help Vader raise a force that would let him coup the Emperor. She was so popular she then got her own comic series, making her the breakout star of the Disney/Marvel Star Wars comics. The Fandom Menace can’t touch her.

Her comics have been a series of frankly strange adventures involving Force artifacts, Vader either working with her or wanting her dead, and double crosses that leave your head spinning. She has Thrawn level tactical abilities, but only for schemes. She is haunted by how her trauma born behaviors make it hard for her to maintain relationships and be a good person. She has so many exes it's an entire section of this tournament. Her most significant relationships have been with Sana Starros and Magna Tolvan. As of the end of the Spark Eternal arc, the comic seems to be leaning towards a poly ending with the three of them, but first Aphra needs to stop self sabotaging.

One of Aphra’s greatest achievements was at the end of her 2016 comic run, where she trapped Vader in a PTSD flashback Force artifact on Tython and hacked his suit to allow her to erase Hoth from the Empire’s records. She did this for the sake of her loved ones who had joined the Alliance. Doing this gave Echo Base enough time to build up before they were found again that they were able to evacuate much more efficiently. That’s right, disaster lesbian love saved the Rebellion.

Kaeden Larte | Identity: queer | Media: Ahsoka novel

Kaeden Larte was a young farmer on the isolated moon of Raada. When she was fourteen her parents died in a farming accident and she was given special permission to take their job. She also became the guardian of her younger sister Miara. When Ahsoka arrived on Raada, Kaeden was quick to welcome her and developed a crush on her. When the Empire arrived, Kaeden joined a resistance cell. Their attack on the Imperial garrison failed, and Ahsoka to save them, was forced to reveal that she was a Jedi. Feeling betrayed that Ahsoka kept such a secret from her, she abandoned their hiding place in the caves and was captured by the Empire. They tortured her, but Ahsoka was able to rescue her. When Ahsoka left Raada to get help, Kaeden was captured again by the Sixth Brother to lure out Ahsoka. When Ahsoka rescued her again, she confessed her feelings, which Ahsoka gave a noncommittal answer to.

After Ahsoka’s battle with the Sixth Brother, the residents of Raada were welcomed to Alderaan. Kaeden eventually went to medical school and afterwards joined the Rebellion as a medic. If she ever reconnected with Ahsoka is unknown. She was present at the medal ceremony at the end of A New Hope.

The episode “Resolve” from Tales of the Jedi is based on the same episode concept as the Ahsoka novel, and thus has potentially retconned Kaeden and replaced her with a white man. However a reference book has attempted to establish the two as just coincidentally similar separate events. The identity “queer” is based off E K Johnston’s statements regarding what orientation she imagined Kaeden with. 

[ominouspositivity-or-else]

But hasn’t the Church often touted the nuclear family as “the epitome of human function”? At least it always seems like that to me, the family is even called “The Domestic Church” and “The Domestic Kingdom.” But at the same time Christian societies in ages past were very much not as individualistic and more community based than modern day… I suppose there is a balance, like in all things…

yeaaaahhhh in a sense

but like it depends heavily on what you mean when you refer to "nuclear".

In the current mindset that's a wife, a husband, and two kids, one boy one girl. It was popularized as the way to structure your life I believe in the American 1950's?

Before that the family was not simply husband, wife, and children, but was a connected group of generations, and in many countries, that's still their idea of what family is. The aunts, uncles, grandparents, and all the family is more closely interconnected. And, in families where this happens, the level of stability is usually higher.

For instance, I grew up fairly close to my grandparents and aunts and uncles. We don't see each other as much as we could, but when we do get together, we're a lot more unified than we would be if we were more separate. On my mother's side, my family is way closer together than on my father's side. I've barely seen my paternal grandparents in the last three years. If you wanted to ask me where i would go for help and love, i'd turn to my maternal side of the family.

When people talk about overturning the nuclear family, they usually mean the destruction of the unit itself. That's not my thought.

My thought is rather that the unit of the basic family is the building block for how our life is supposed to be. This is backed up by the Catechism of the Catholic Church, which reads, "The family is the original cell of social life"(2207).

To break the family down into little boxes and say that the epitome of family, the ideal, is an isolated man and woman who care for their own kids and don't interfere with others is a very odd idea, and highly alien from human history.

How many of us in this current generation have stories that have been passed down? How many of us know about our own families? There is a reason that Ancestry.Com has a market. People don't know who they are, and that's an integral thing for a human being. We were structured for family, but not only a family, but our family.

Perhaps many people have to break free from toxic and broken families they were born into. You can build up the new one you create.

The nuclear family, in my opinion, and for a ton of the history of Western and probably Eastern Civilization was a basic building block. It was not the triumph, but rather the beginning. It was not the building, but a brick.

[sanemyamen]

Magnetic Beads Market Outlook: World Approaching Demand & Growth Prospect 2022-2027

Global Magnetic Beads Market Report from AMA Research highlights deep analysis on market characteristics, sizing, estimates and growth by segmentation, regional breakdowns & country along with competitive landscape, players market shares, and strategies that are key in the market. The exploration provides a 360° view and insights, highlighting major outcomes of the industry. These insights help the business decision-makers to formulate better business plans and make informed decisions to improved profitability. In addition, the study helps venture or private players in understanding the companies in more detail to make better informed decisions.

Major Players in This Report Include Thermo Fisher Scientific Inc (United States),Merck KGaA, Darmstadt (Germany),Polysciences, Inc. (United States),Qiagen (Germany),MagQu Co. Ltd. (Taiwan),FUJIFILM Wako Pure Chemical Corporation (Japan),Takara Bio Inc. (Japan),Spherotech Inc (United States),Cube Biotech GmbH (Germany),Lab on a Bead AB (Sweden)

Magnetic beads & particles are used as carriers of antibodies, antigens, catalyzers, proteins as well as nucleic acids, allowing action on viruses, cells, bacteria, & other biological entities. Magnetic beads are an ultimate tool for immobilizing molecules such as proteins or nucleic acids on a solid phase. They can be additionally used in many applications. This magnetic bead separation process is an efficient, rapid, clean which many scientists are using to substitute centrifugation, filtration, as well as separation techniques. These are used for immunoprecipitation applications. These ensure the rapid & reproducible isolation of proteins. Market Drivers Growing Number of Life Sciences Research Activities

Rising Need to Identify Antigens That Are Related With Autoimmune Diseases

High Demand in The Biopharmaceuticals Field Involving The Application, Opportunities For New Innovation in The Field of Life Science

Opportunities Growing Genomics & Proteomics Research with the Increasing Adoption of Immunoprecipitation in the Coming Years

Growing Funding for Cell Based R&D by Government and Biotechnology companies

Challenges Quality Concerns over Research Antibodies

The Magnetic Beads market study is being classified by Application (Human Cell Separation, Animal cell separation (clinical study), Secondary cell separation), End Users (Healthcare Facilities (Hospitals, Clinics, and Others), Individual Pathology Labs, Research Institutes, Others), Magnetic Beads Size (Small beads (1-10 µm), Medium beads (20-40 µm), Large beads (70-120 µm)), Isolation Technique (Positive, Negative, Others (Depletion, and Others)) Presented By

AMA Research & Media LLP

[colinwilson11]

Cell Cytometry Market Poised To Expand Rapidly Due To Growing Investment In R&D Activities

The cell cytometry market allows observation, analysis, separation and purification of cells using multiple parameters of light scattering, fluorescent dyes and other optical instrumentation. Cell cytometry helps understanding cell populations, cell characteristics, cell structures and analyzing cellular functions at single-cell level. It aids in research associated with cancer, AIDS, and other diseases and has applications in areas of immunology, hemopathology and stem cell research.

The cell cytometer market includes flow cytometers, high-content screening systems, and other equipment, reagents, and software. Flow cytometers are most widely used cell analyzers that allow multiparametric analysis of physical and biochemical characteristics of single cells suspended in fluid medium. The increasing prevalence of chronic and infectious diseases is driving growth in cell-based research activities and clinical applications of cell cytometry technologies.

The Cell Cytometry Market is estimated to be valued at US$ 1.5 Bn in 2024 and is expected to exhibit a CAGR of 9.9% over the forecast period 2024-2031.

Key Takeaways

Key players operating in the cell cytometry market are Agilent, Beckton Dickinson, Beckman Coulter Life Sciences, Bio-Rad, and ThermoFisher Scientific. Key players are focusing on developing advanced flow cytometer systems and reagents with increased sensitivity, higher throughput, and expanded application areas. For instance, in 2022 Agilent launched NovoCyte Penta which provides 5 lasers for multicolor assays.

The cell cytometry market is witnessing high growth due to increasing demand for disease diagnostics and therapeutics related to immunology, cancer, and stem cell research. Growing biopharmaceutical industry investments in cell-based research and biomarker discovery arefueling adoption of cell analysis platforms. The advancements in single-cell analysis technologies are augmenting market opportunities in translational research, personalized medicine and drug discovery.

Technological advancements are playing a major role in market growth. Integration of informatics and artificial intelligence solutions in cell analysis platforms is helping to improve data analysis and accelerate scientific discoveries. Adoption of microfluidic chips and microfluidics technologies is supporting development of compact portable instruments with high sensitivity for point-of-care applications. Automation of workflow processes using robotics is enhancing throughput and reproducibility.

Market Trends

Two major trends are driving innovation in the cell cytometry market. First, the incorporation of artificial intelligence and machine learning algorithms in cell analysis software is helping in automated segmentation, gating, classification and biomarker identification from large and complex flow and imaging cytometry data sets. This aids high content analysis and phenotypic screening applications. Second, the development of cell isolation platforms integrated with downstream multi-omics capabilities for single-cell proteomics, transcriptomics and genome analysis is supporting personalized medicine initiatives like cancer immunotherapy development.

Market Opportunities

Emerging economies in Asia Pacific and Latin America represent major growth opportunities for cell analysis product manufacturers due to increasing pharmaceutical outsourcing, rising healthcare investments and establishment of new life sciences research institutes. Second, the expansion of stem cell based research and growing adoption of cell therapy products will augment demand for cell sorting, cell characterization and potency analysis capabilities. This offers novel opportunities for companies to introduce specialized cell analysis platforms.

The covid-19 pandemic has negatively impacted the growth of the cell cytometry market in the short run. During pre-covid times, the market was growing at a steady pace due to increased investments in r&d for drug development and discovery. However, nationwide lockdowns imposed travel restrictions and disrupted the global supply chains. This affected the procurement of key instruments, reagents and consumables necessary for cell cytometry procedures in research laboratories and healthcare facilities.

With lockdowns easing in late 2020, the market is recovering slowly as r&d activities are resuming. However, budgetary reallocations to test,treat and vaccinate large populations have reduced funding available for non-covid research. This is hampering the market growth. The key players are struggling to enhance production capacities due to labour shortages and raw material delays. They are now focusing on developing reagents and assays suited for covid-19 research to leverage new opportunities.

Going forward, collaborations between industry and academia will be important to expand the applications of cell cytometry in vaccine development,immune response monitoring and target identification for covid therapeutics. Government support through public-private partnerships can help bolster healthcare infrastructure and rebuild market confidence. Automated high throughput platforms allowing for fast,simultaneous processing of samples can aid in pandemic preparedness. Finally, virtual demonstrations and online training programmes can compensate for restrictions on field interactions until the pandemic subsides fully.

North America is currently the largest market for cell cytometry accounting for over 40% of the global revenues, followed by Europe and Asia Pacific. This is due to extensive r&d spending and presence of leading lifesciences companies and research institutes in USA and Western Europe which are early adopters of advanced cell analysis technologies. The Asia Pacific region excluding Japan presents the strongest growth prospects during the forecast period, propelled by increasing healthcare investments,expanding biotech industries and rising affluence in populous nations like China and India.

Over the next decade, cell cytometry markets in countries like Brazil, South Korea and Saudi Arabia are also expected to grow substantially under the influence of supportive government policies and initiatives driving innovation. The universal need to better understand disease mechanisms, accelerate drug development and improve clinical outcomes will continue driving the long term demand for cell analysis technologies regardless of ongoing economic or health sector challenges.

Get more insights on this topic: https://www.ukwebwire.com/cell-cytometry-market-is-estimated-to-witness-high-growth-owing-to-advancements-in-multi-color-flow-cytometry/

About Author:

Priya Pandey is a dynamic and passionate editor with over three years of expertise in content editing and proofreading. Holding a bachelor's degree in biotechnology, Priya has a knack for making the content engaging. Her diverse portfolio includes editing documents across different industries, including food and beverages, information and technology, healthcare, chemical and materials, etc. Priya's meticulous attention to detail and commitment to excellence make her an invaluable asset in the world of content creation and refinement. (LinkedIn - https://www.linkedin.com/in/priya-pandey-8417a8173/)

What Are The Key Data Covered In This Cell Cytometry Market Report?

:- Market CAGR throughout the predicted period

:- Comprehensive information on the aspects that will drive the Cell Cytometry Market's growth between 2024 and 2031.

:- Accurate calculation of the size of the Cell Cytometry Market and its contribution to the market, with emphasis on the parent market

:- Realistic forecasts of future trends and changes in consumer behaviour

:- Cell Cytometry Market Industry Growth in North America, APAC, Europe, South America, the Middle East, and Africa

:- A complete examination of the market's competitive landscape, as well as extensive information on vendors

:- Detailed examination of the factors that will impede the expansion of Cell Cytometry Market vendors

FAQ’s

Q.1 What are the main factors influencing the Cell Cytometry Market?

Q.2 Which companies are the major sources in this industry?

Q.3 What are the market’s opportunities, risks, and general structure?

Q.4 Which of the top Cell Cytometry Market companies compare in terms of sales, revenue, and prices?

Q.5 Which businesses serve as the Cell Cytometry Market’s distributors, traders, and dealers?

Q.6 How are market types and applications and deals, revenue, and value explored?

Q.7 What does a business area’s assessment of agreements, income, and value implicate?

*Note: 1. Source: Coherent Market Insights, Public sources, Desk research 2. We have leveraged AI tools to mine information and compile it

[blueweave]

Chimeric antigen receptor (CAR) T-cell therapy is a technique that uses genetic engineering to modify T cells, a subset of white blood cells, to enable them to recognize and eliminate cancerous cells. Because CAR T-cell therapy modifies T cells' genes to enable them to fight cancer, it is occasionally referred to as a form of cell-based gene therapy.

Even in cases where alternative treatments are no longer effective, this kind of care can help treat specific cancers.

How CAR T-cell therapy work

In CAR T-cell therapies, T cells are taken from the patient's blood and are changed in the lab by adding a gene for a receptor (called a chimeric antigen receptor or CAR), which helps the T cells attach to a specific cancer cell antigen. The CAR T cells are then given back to the patient.

CAR T-cell therapy can take a few weeks to complete.

Leukapheresis is the first procedure used to separate white blood cells (including T cells) from the patient's blood. Patients typically lie in bed or recline in a reclining chair for this operation. Because blood is drawn from one IV line, white blood cells are extracted, and then the blood is reinfused, two IV lines are required. Patients typically lie in bed or recline in a reclining chair for this operation. White blood cells are extracted from the blood through one IV line, and the blood is reinfused into the body through the other, necessitating the use of two IV lines. Central venous catheters, a unique kind of IV line with both IV lines integrated in, are occasionally utilized.

For two to three hours during the process, the patient will need to remain seated or in a prone position. During leukapheresis, blood calcium levels might occasionally fall, which can result in tingling and numbness as well as muscle spasms. The replacement of calcium, which can be either intravenously or orally, can be used to treat this.

Once the white cells are extracted, the T cells are isolated, transferred to a laboratory, and manipulated by introducing the gene corresponding to the particular chimeric antigen receptor (CAR). They are therefore CAR T cells. Then, in the lab, these cells are expanded and multiplied. The production of the vast quantity of CAR T cells required for this treatment can take many weeks.

Once sufficient CAR-T cells have been produced, they will be returned to the patient. The patient may get chemotherapy a few days before to the CAR T-cell infusion in order to assist reduce the quantity of other immune cells. This increases the likelihood that the CAR T cells will become activated to combat the malignancy. Because CAR T cells function best while there are still some cancer cells to assault, this chemotherapy is typically not very strong. The CAR T cells proliferate and have the ability to aid in the destruction of other cancer cells once they attach to cancer cells.

Some of the approved CAR T-cell therapies include:

Tisagenlecleucel, also known as tisa-cel (Kymriah)

Axicabtagene ciloleucel, also known as axi-cel (Yescarta)

Brexucabtagene autoleucel, also known as brexu-cel (Tecartus)

Lisocabtagene maraleucel, also known as liso-cel (Breyanzi)

Idecabtagene vicleucel, also known as ide-cel (Abecma)

Ciltacabtegene autoleucel, also known as cilta-cel (Carvykti)

Market Of CAR-T Cell Therapy

The market for CAR T-cell treatment was estimated to be worth USD 2.75 billion globally in 2022. From 2023 to 2030, it is projected to expand at a compound annual growth rate (CAGR) of 23.32%, peaking at USD 15.97 billion. Increased cancer prevalence, clinical success, regulatory approvals, and expanding indications are some of the factors driving the market. But the medications' side effects and exorbitant costs could also impede expansion.

The pipeline highlights of CAR-T cell therapy are following

In August 2023, the US FDA granted orphan drug designation (ODD) to NXC-201 (Nexcella), a next generation chimeric antigen receptor (CAR) T-cell therapy, for the treatment of patients suffering from multiple myeloma.

In August 2023, Invectys announced that FDA granted a Fast Track Designation to the chimeric antigen receptor (CAR) T-cell therapy, IVS-3001, which is used for the treatment of patients suffering from renal cell carcinoma.

In August 2023, GenScript Biotech entered into a strategic agreement with T-MAXIMUM Biotech with an aim to develop CAR T cell therapy by using GenScript’s CRISPR nucleic acid reagents

In January 2023, CARsgen Therapeutics had announced a collaboration with Huadong Medicine to commercialize zevorcabtagene autoleucel (zevor-cel), CT053, in mainland China. Under the collaboration, Huadong Medicine will have the exclusive right to commercialize CARsgen’s CT053 in mainland China. According to the deal, CARsgen will receive $29.7m (RMB200m) in upfront payment and is also eligible for up to $152.4m (RMB1,025m) in regulatory and commercial milestones.

In December 2022, Arcellx, Inc. announced a global strategic collaboration to co-develop and co-commercialize Arcellx's lead late-stage product candidate, CART-ddBCMA, for the treatment of patients with relapsed or refractory multiple myeloma. Currently in Phase 2 clinical development, CART-ddBCMA is an investigational cell therapy product comprising autologous T cells that have been genetically modified to target multiple myeloma. CART-ddBCMA utilizes Arcellx's novel D-Domain binder. Kite and Arcellx will jointly advance the CART-ddBMCA asset.

In December 2022, CARsgen Therapeutics Holdings Limited announced that at the 2022 American Society of Hematology (the "ASH") Annual Meeting, the Company presented a poster with the results of the phase I/II LUMMICAR STUDY 1 clinical trial of zevorcabtagene autoleucel. Results for the 14 subjects treated in phase I of LUMMICAR STUDY 1 showed a well-tolerated safety profile, plus deep and durable responses with an objective response rate (ORR) of 100% and a complete response/stringent complete response (CR/sCR) rate of 78.6%.

In October 2022, CARsgen Therapeutics Holdings Limited announced that the National Medical Products Administration (NMPA) of China has accepted the New Drug Application (NDA) for zevorcabtagene autoleucel for the treatment of relapsed and/or refractory multiple myeloma (R/R MM). The acceptance of the NDA was based on data from an open-label, single arm Phase I/II clinical trial (LUMMICAR STUDY 1 [Protocol number CT053-MM-01]) in China. Study results showed that zevor-cel has excellent safety and efficacy profiles. Zevor-cel also represents a promising treatment option for patients with high-risk disease.

In August 2022, Poseida Therapeutics, Inc. announced it has entered into a broad strategic collaboration and license agreement with Roche, focused on developing allogeneic CAR-T therapies directed to hematologic malignancies. The global collaboration covers the research and development of multiple existing and novel "off-the-shelf" cell therapies against targets in multiple myeloma, B-cell lymphomas and other hematologic indications.

Conclusion

CAR T-cell therapy is a rapidly growing segment within the broader immunotherapy market, offering a transformative approach to cancer treatment. The therapy involves modifying a patient's T cells to recognize and destroy cancer cells, providing personalized and highly targeted treatment. The CAR T-cell therapy market is expected to grow significantly due to advancements in biotechnology and increasing approval of CAR T-cell therapies for various cancer types. Ongoing research and development are likely to result in more effective therapies with fewer side effects. The market is becoming increasingly competitive, with several biotech and pharmaceutical companies developing CAR T-cell therapies. Collaborations, mergers, and acquisitions are common as companies seek to strengthen their portfolios and market positions.

Contact Us:

BlueWeave Consulting & Research Pvt. Ltd.

+1 866 658 6826 | +1 425 320 4776 | +44 1865 60 0662

info@blueweaveconsulting.com

[industryinsightsandanalysis]

Chromatography Resin market is expected to display a steady growth by 2028

According to a new report published by UnivDatos Markets Insights the Chromatography Resin Market is expected to grow at a CAGR of around 8% from 2022-2028. The analysis has been segmented into Type (Inorganic, Natural and Synthetic); Application (Affinity, Ion Exchange, Size Exclusion, Hydrophobic Interaction and Others); Region/Country.

The Chromatography Resin market report has been aggregated by collecting informative data on various dynamics such as market drivers, restraints, and opportunities. This innovative report makes use of several analyses to get a closer outlook on the Chromatography Resin market. The Chromatography Resin market report offers a detailed analysis of the latest industry developments and trending factors in the market that are influencing the market growth. Furthermore, this statistical market research repository examines and estimates the Chromatography Resin market at the global and regional levels.

Market Overview

The chromatography resin market is expected to witness CAGR of 8% during the forecast period owing to the advent of biosimilars and growing pharmaceutical & biopharmaceutical R&D activities for drug delivery applications. Further, chromatographic resins are used to purify and separate proteins and other bio-molecules in biotechnological, pharmaceutical, food industries.

In addition, Chromatography resins also have applications in commercial processes like water purification and environmental analysis. A rise in R&D investment is anticipated to enhance the need for chromatography, which is a crucial component of R&D operations in the pharmaceutical sector. According to Congressional Budget Office USA, the pharmaceutical industry spent USD 83 billion dollars on R&D in 2019.

Moreover, strategic measures like mergers and acquisitions, partnerships, etc. is further expected to drive the market. For instance, in April 2020, Bio-Rad Laboratories Inc. announced the acquisition of Celsee Inc., a company that offers instruments and consumables for the isolation, detection, and analysis of single cells

COVID-19 Impact

The recent covid-19 pandemic has disrupted the world and has brought a state of shock to the global economy. The global pandemic has impacted the healthcare industry and has transformed the way healthcare is delivered. The COVID-19 pandemic, on the other hand, has bolstered the Chromatography Resin business by boosting the use of vaccinations and medications, resulting in increased demand for Chromatography Resin.

The global Chromatography Resin market report is studied thoroughly with several aspects that would help stakeholders in making their decisions more curated.

Based on technique, the market is classified into Affinity, Ion Exchange, Size Exclusion, Hydrophobic Interaction and Others. Affinity resin has a sizable portion of the market and is frequently used for protein purification due to its characteristics including high binding efficiency, low ligand leaking, and selectivity for a variety of antibody segments. Comparing affinity chromatography to other techniques, it has the benefit of using a protein structure for purifying. This makes affinity chromatography more easy and time-effective.

Based on type, the market is classified into Inorganic, Natural and Synthetic. A sizeable portion of the market is accounted for by the natural sector, which can be attributed to rising natural product consumption as well as widespread use of size exclusion chromatography and paper chromatography in various industrial applications. Key market drivers include the growing demand from the food and beverage industry as well as the pharmaceutical and medical sectors, which are expanding due to the increase in healthcare spending.

Chromatography Resin Market Geographical Segmentation Includes:

North America (United States, Canada, and Rest of North America)

Europe (Germany, United Kingdom, Italy, France, Spain, and the Rest of Europe)

Asia-Pacific (China, India, Japan, and the Rest of Asia-Pacific)

Rest of the World

For a better understanding of the market dynamics of the Chromatography Resin market, a detailed analysis was conducted for different regions across the globe including North America (U.S, Canada, and the Rest of North America), Europe (Germany, France, Spain, United Kingdom, Italy, and Rest of Europe), Asia-Pacific (China, India, Australia, Japan, and Rest of APAC), Rest of World has been conducted. Geographically, the North America region dominated the Chromatography Resin market owing to the growing investment in healthcare sector in the region.

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The major players targeting the market include

Cytiva Lifesciences

Bio-Rad Laboratories Inc.

Sartorius AG

Generon

Tosoh Bioscience

Bio-Works

Repligen Corporation

LAF-Biotechnology

JNC Corporation

Anatrace Products LLC.

Competitive Landscape

The degree of competition among prominent global companies has been elaborated by analyzing several leading key players operating worldwide. The specialist team of research analysts sheds light on various traits such as global market competition, market share, most recent industry advancements, innovative product launches, partnerships, mergers, or acquisitions by leading companies in the Chromatography Resin market. The major players have been analyzed by using research methodologies for getting insight views on global competition.

Key questions resolved through this analytical market research report include:

• What are the latest trends, new patterns, and technological advancements in the Chromatography Resin market?

• Which factors are influencing the Chromatography Resin market over the forecast period?

• What are the global challenges, threats, and risks in the Chromatography Resin market?

• Which factors are propelling and restraining the Chromatography Resin market?

• What are the demanding global regions of the Chromatography Resin market?

• What will be the global market size in the upcoming years?

• What are the crucial market acquisition strategies and policies applied by global companies?

We understand the requirement of different businesses, regions, and countries, we offer customized reports as per your requirements of business nature and geography. Please let us know If you have any custom needs.

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[globalgrowthinsights]

Artificial Cornea and Corneal Implant Market: Dissecting the Factors Steering Growth and Potential Risks

Artificial Cornea and Corneal Implant Market provides in-depth analysis of the market state of Artificial Cornea and Corneal Implant manufacturers, including best facts and figures, overview, definition, SWOT analysis, expert opinions, and the most current global developments. The research also calculates market size, price, revenue, cost structure, gross margin, sales, and market share, as well as forecasts and growth rates. The report assists in determining the revenue earned by the selling of this report and technology across different application areas.

Geographically, this report is segmented into several key regions, with sales, revenue, market share and growth Rate of Artificial Cornea and Corneal Implant in these regions till the forecast period

North America

Middle East and Africa

Asia-Pacific

South America

Europe

Key Attentions of Artificial Cornea and Corneal Implant Market Report:

The report offers a comprehensive and broad perspective on the global Artificial Cornea and Corneal Implant Market.

The market statistics represented in different Artificial Cornea and Corneal Implant segments offers complete industry picture.

Market growth drivers, challenges affecting the development of Artificial Cornea and Corneal Implant are analyzed in detail.

The report will help in the analysis of major competitive market scenario, market dynamics of Artificial Cornea and Corneal Implant.

Major stakeholders, key companies Artificial Cornea and Corneal Implant, investment feasibility and new market entrants study is offered.

Development scope of Artificial Cornea and Corneal Implant in each market segment is covered in this report. The macro and micro-economic factors affecting the Artificial Cornea and Corneal Implant Market

Advancement is elaborated in this report. The upstream and downstream components of Artificial Cornea and Corneal Implant and a comprehensive value chain are explained.

Browse More Details On This Report at @https://www.globalgrowthinsights.com/market-reports/artificial-cornea-and-corneal-implant-market-100558

 Global Growth Insights

Web: https://www.globalgrowthinsights.com

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[soumyafwr]

Cell Isolation or Cell Separation Market 

[healthcaremarketanalysis]

Cell Dissociation Market worth $1.4 billion by 2028

The global cell dissociation market in terms of revenue was estimated to be worth $0.6 billion in 2023 and is poised to reach $1.4 billion by 2028, growing at a CAGR of 17.8% from 2023 to 2028.

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Cell dissociation Market Dynamics

Driver: Increase in recombinant therapeutics sourced from mammalian cells

The biopharmaceutical industry has witnessed a considerable increase in the proportion of recombinant therapeutics sourced from mammalian cells since 2002. The number of approved recombinant products from mammalian cell culture increased by 8.5% annually from 2002 to 2022. As of June 2022, more than 300 recombinant products have been commercialized, indicating a rapid shift towards mammalian-based therapeutics, which nearly account for 67% of therapeutics in 2022. .Cell culture products, including cell dissociation form an integral part of developing mammalian-based recombinant therapeutics, propelling the industry growth.

Restraint: High cost of cell-based research

Isolation and purification of cell organelles integrates expensive products, additionally, automated/sem-automated benchtop instruments are more expensive than traditional methods. Despite significant benefits offered by automated instruments, high costs associated with these instruments may limit the adoption of products further restraining the market growth.

Opportunity: Advancements in non-enzymatic tissue dissociation

Companies operating in the market are introducing innovative and advanced products to overcome competition and generate more revenue. Most researchers in R&D institutes and biotechnology companies have primarily relied on traditional enzymatic dissociation products to separate cells from primary tissues. Although these traditional enzymatic dissociation products have advantages, such as better dissociation while performing research, they can sometimes be cytotoxic and damage viable cells. To overcome this issue and differentiate their product offerings, several companies are introducing non-enzymatic products that are non-cytotoxic. Owing to this advantage, the demand for non-enzymatic dissociation products is increasing among several end users.

Challenge: Limitations associated with dissociated cell culture

The key limitation of dissociated cultures is the small number of cells relative to immortalized cell lines. This makes it difficult to perform biochemical experiments requiring a high starting material volume. Additionally, most primary cell cultures are not homogeneous, which poses a challenging scenario for cell dissociation experiments. Neuronal cultures are often mixtures of both glia and neurons that respond to different neurotransmitters, so identifying an individual population of cells can be difficult.

North America dominates the global cell dissociation market

The cell dissociation market is segmented into five major regional segments, namely, North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. In 2022, North America accounted for the largest share in the cell dissociation market, which is attributed to increasing investments in the development of novel cell-based therapies.

The cell dissociation market is moderately consolidated in nature with prominent market players such as Merck KGaA (Germany), Danaher Corporation (US), Thermo Fisher Scientific, Inc. (US), Corning Incorporated (US), Becton, Dickinson and Company (US), STEMCELL Technologies (Canada), PromoCell GmbH (Germany), Miltenyi Biotec (Germany), ATCC (US), HiMedia Laboratories (India), PAN-Biotech (Germany), CellSystems GmbH (Germany), AMSBIO (England), Neuromics (US), VitaCyte, LLC. (US), ALSTEM (US), Biological Industries (Israel), Gemini Bio (US), Innovative Cell Technologies, Inc. (US), Central Drug House (P) Ltd. (India), Worthington Biochemical Corporation (US), Capricorn Scientific (Germany), Abeomics (US), and Genlantis, Inc. (US).

Recent Development of Cell Dissociation Industry

In 2020, Miltenyi Biotec launched automated and closed adherent cell culture solutions on CliniMACS Prodigy.

In 2020, Merck The company expanded its Life Sciences production facilities in Danvers, Massachusetts, and Jaffrey, New Hampshire (US).

In 2020, STEMCELL Technologies partnered with CollPlant to secure CollPlant rhCollagen for STEMCELL’s use in cell culture applications.

In 2021, Danaher (Cytiva) partnered with Diamyd Medical, wherein Diamyd selected Cytiva’s FlexFactory platform for making precision medicine type-1 diabetes vaccines.

In 2021, Danaher (Cytiva) collaborated with the Government of Telangana (India) to strengthen the biopharma industry in India with new labs.

Cell Dissociation Market Advantages:

Increased Efficiency: Cell dissociation reagents provide a more efficient and reliable method for dissociating cell samples, which can significantly reduce processing time and improve the quality of the results.

Higher Yields: Cell dissociation reagents are designed to maximize cell yield, allowing for more effective downstream applications such as flow cytometry and immunological assays.

Improved Quality: Cell dissociation reagents help to ensure that cells are undamaged during the isolation process, thereby resulting in higher quality samples.

Cost Effective: Cell dissociation reagents provide a cost-effective solution, as they are typically less expensive than traditional methods.

Greater Flexibility: Cell dissociation reagents offer greater flexibility in terms of the types of cells that can be isolated, allowing for a wider range of downstream applications.

Related links:

[bioandpharmaanalyst]

Understanding the Cell Separation Technologies Market: Trends, Opportunities, and Challenges

Cell separation technologies are at the forefront of biomedical research, providing essential tools for isolating specific cell types from complex biological mixtures. This article explores the current landscape, key drivers, emerging trends, and future prospects of the cell separation technologies market. Get Free Request Sample Report @…

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Biotechnology Reagents and Kits Market will grow at highest pace owing to increasing R&D activities in biopharmaceutical companies

Biotechnology reagents and kits are used for several diagnostic and research applications including isolation, purification, and analysis of DNA and RNA. Some key products in this market include cell and tissue culture reagents, chromatography reagents, electrophoresis reagents, immunohistochemistry reagents, nucleic acid extraction and purification reagents, PCR reagents, flow cytometry reagents, electrophoresis reagents, and separation and filtration reagents. Growing funding for biotechnology research along with rising prevalence of chronic diseases has increased the demand for biotechnology reagents and kits. Advancements in biologics and personalized medicine require reagents and kits for molecular analysis of patient samples which has fueled market growth.

The Global Biotechnology Reagents and Kits Market is estimated to be valued at US$ 718.8 Mn in 2024 and is expected to exhibit a CAGR of 23% over the forecast period 2023 to 2030.

Key Takeaways Key players operating in the Biotechnology Reagents and Kits are Medtronic Plc, Hill-Rom Holdings, Inc. (Welch Allyn), iRythm Technologies, Inc., AliveCor, Inc., Vivalnk, Inc., Cardiac Insight Inc., VitalConnect, LifeSignals, Inc., Lâ€TMoreal Group, Dexcom, Inc., GENTAG, Inc., Abbott Laboratories, Koninklijke Philips N.V. and other prominent players. These players are focusing on new product development and launches to expand their product portfolio. For instance, in 2022 Medtronic Plc launched Clara Smart Pancreas System which uses RTSM technology to automatically suspend insulin delivery. The demand for biotechnology reagents and kits is growing owing to increasing demand of personalized medicine, genomics applications and cell and gene therapy research. Pharmacogenomics, companion diagnostics and molecular biomarkers are driving the need for reagents and assays utilized in the discovery, development and commercialization of personalized medicine. Growing R&D spending on developing new biologics and rising application of big data analytics in drug development is also fueling market growth. Technological advancements are expanding application of biotechnology reagents and kits in new areas. For example, next generation sequencing techniques have enabled large-scale sequencing of genomes which requires reagents for sample preparation and library preparation steps. Rapid diagnostics technologies are allowing point-of-care application of reagents for fast detection of infectious diseases. Automated instruments with integrated reagent kits are increasing efficiency and reproducibility of experiments in core labs. Market trends: 1. Growing preference for personalized medicine/ precision medicine. Biomarker discovery and validation requires biomarker detection assays which is propelling demand for immunohistochemistry, PCR and other reagents. 2. Increasing focus on contract research and contract manufacturing. CROs and CMOs require a continuous supply of biotechnology reagents and kits for conducting research and manufacturing activities on behalf of biopharma companies. Market Opportunities: 1. Emerging markets in Asia Pacific offer high growth potential. Countries like China, India and South Korea are witnessing increasing biotech research and bulk drug production which will drive the need for reagents in coming years. 2. Cell and gene therapy is a major area of focus. Reagents are essential for quality control testing, process development and scalable manufacturing of cell and gene therapies. This represents a lucrative opportunity for leading reagents players.