#Anne Plotkin
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Harold with his daughter Violet and his ex wife Anne Plotkin.
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BOOK REVIEW:
GHOSTBUSTER' S DAUGHTER - LIFE WITH MY DAD HAROLD RAMIS (VIOLET RAMIS STIEL)

@amalthea9 @professorlehnsherr-almashy @angelixgutz @the-blue-fairie @princesssarisa @themousefromfantasyland @scarletblumburtonofeastlondon @thealmightyemprex @bixiebeet
I got curious about this book for a while after seeing posts of pages, pictures and quotes from it here on Tumblr.
I finally got to listen the audiobook, in a site that provided it for free that downloaded it from Audible.
The story of how the conception of this book happened is interesting: the author, Violet Ramis Stiel, initially tought of writing a collaborative book about parenting with her father, Harold, when he was still alive and she had just become the parent of two children.
They intended it to be a project where they would compare and contrast their perspectives on parenthood and share those perspectives with the public.
Sadly, Harold Ramis got ill and passed away in 2014, before getting a chance to write a paragraph of the provisionally titled We're All Gonna Die, Now Go To Sleep.
During the period of mourning, while corresponding with friends and fans of her father's work online, Violet mentioned the idea of the book about parenting.
And people encouraged her to write the book, even tough her father passed away and it did turn into something different than originally intended.
So, this book, published in 2018, was the result. After sharing a letter she wrote right after Harold's passing as a way to proccess her grief and briefly introducing her father's birth date and place and who his parents were, she goes to what she calls her beggining, telling about the peculiar romance and eventual marriage of her parents, Harold and Anne Plotkin, in 1967, soon after they graduated college, and his change of jobs from psychiatric hospital caregiver, to farmer for a week, to taxi driver, to freelance journalist, before his joining of the Second City and National Lampoon Radio Hour troupes, where he really discovered his vocation for audiovisual arts and comedy while his wife developed her talent for painting.
In 1977, Harold and Anne decide to have a baby, with Anne specially seeing this as an adventure to go with the flow, and in that same year, Violet was conceived and born, and because Anne had a complicated childhood and also suffered from post partum depression in a time that it wasn't really understood, Harold became Violet's primary parent, feeding her, bathing her, nursing her when she got sick, and joining her in her naps.
Besides this inversion of roles, other aspects that made the family unconventional was that they were very open in talking to little Violet about things like sex and drugs (wich both members of the couple consumed alongside their friends from artistic circles), traveled a lot, and had a deal where each one could have relationships with other people, as long as the other returned home.
From 1978 forward, after his work on television in the first two seasons of SCTV, we get information about Harold Ramis slowly getting experience in filmaking, enjoying the success of Animal House, wich he wrote with Doug Kenney, despite the fact that he got frustrated when John Landis acted controling as a director and didn't cast him in one of the roles, the complicated production of his directorial debute, Caddyshack, to later have a more narratively consistent success with National Lampoon's Vacation, writing and acting in an important role in Stripes and writing and acting in his most famous work, Ghostbusters.
After this period of slowly getting success in the movie industry, there comes the production of his next film as a director, Club Paradise, which os overall fun backstage (him once getting arrested by the Jamaican Police for posession of marijuana not withstanding), is not a box ofice hit.
It was around this time that Harold had an affair with director Amy Heckerling, when both were still married to their respective spouses, which got her pregnant with his second child, Molly, and for a variety of reasons, he regretfully distanced himself from that child until years later, when a DNA test revealed that she wasn't biologically related to her mother's then husband, and eventually she decided to contact Harold, becoming close to him and, specially, Violet.
This complicated development is told divided in three chapters.
By the late 1980s, Harold works in the more luke warm received Ghostbusters II, divorces from Anne, falls in love with production assistant Erica Mann and eventually proposes and gets married to her.
Violet's custody is shared between Harold and Anne, which is a challenge because each household has a different aproach in raising her: whereas Anne keeps being free spirited and letting her loose, at Harold and Erica's house there are more extricted rules, to which Violet reacts by becoming more gloomy and rebelious. To add more complications, she is bullied at school, and her mother starts to date a man who turns out to be a pedophile and sexually abuses Violet, who, despite constantly blaming herself in her mind, eventually gets the courage to denounce him to her parents, with her father acting specially protective and suportive.
The 1990s start, and in paralell to Harold's success as a director with the acclaim of Groundhog Day, his personal life still gets in turmoil, with his backstage fight with Bill Murray, Violet still acting in a rebellious and gloomy way that even involves a fascination with the gangster life style, and a night where he and his two young songs get hold at gunpoint by two robbers at their home in Los Angeles.
At 16, Violet gets pregnant for the first time, and after repressing herself in secrecy, she shares her plight with her family, who support her when she decides to get an abortion.
Is after this moment that her unstable fase starts to go away, and she starts to open herself to dialogue and retakes a loving relationship with her family.
The later half of the 1990s come, and Violet graduate in college with honors, while Harold presents another directorial critical and comercial success with Analize This. Her father comes clean to her about having another child that he was distant from during a trip they make together.
Come the 2000s, and with it, a lukearm reception to Harold's remake of Beddazled, the family proccessing the trauma of 09/11/2001, Violet figuring out her career ambitions until deciding to become a Social Worker, and having two kids of her own.
Harold continues to work, with his movie The Ice Harvest receiving mixed reactions, while as an actor, he is complimented for his performances in Orange County and Knocked Up.
Violet parts ways with the father of her first two children and eventually finds a new love who becomes her now husband.
Harold works in Year One, the biblical satire that he hopes to be his next important movie. Unfortunally, lack of rewritings due a writers strike coinciding with the production and the studio changing the movie's rating rom R to PG 13 harm the quality of the movie, and when it comes out, is a financial and critical failure.
Harold has to deal with a period of depression, from which he slowly comes out with the help of his friends and family.
Until it returns, heavier, alternating with glimpses of calm and hope, when he suffers an infection that slowly turns into the brain disease that would take away his strength to walk, his ability to hear and talk, and kill him.
We follow the narration of his agonizing, the grief of his family, and end with a full circle, as Violet returns to the memory of the conception of the book, and writes a new leather to her father in the afterlife.
I already enjoy biographies, calling them "a more (at least appearance wise) respectfull gossip magazine".
And yes, there are elements that feel like reading a gossip, while other times it feels like a book of funny anedoctes, a novel, a film history book, a series of philosophical diaries, and the guide to parenting that it was originally imagined to be.
I was surprised and chocked at some moments, laughed at others, and specially was in the verge of tears as the book was coming to an end, knowing that it was based in real life and so we were coming to Violet's loss of her father, but still wishing for a happy ending, like watching a tragic play where you know the ending will be sad, but still hopes that the characters will end happily ever after.
Trough this sharing of their life together, the story of Violet and her father Harold explores a lot of themes: artistic and sociopolitical influences, the art of filmaking, fame, consumerism, gender roles, family dinamics, friendship, faith and spirituality, grief and trauma and the eventual peace we can slowly find when focusing on the good moments we had with our loved ones when they were alive, rather than just on the fact that they are phisically gone.
I'm glad that she decided to share that complex, but not complicated story, and I got to listen to it, and be touched by it.
Highly recomend it, specially for people who are enthusiasts about film history.
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Pictures of baby Violet Ramis Stiel with her parents, Harold Ramis and Anne Plotkin, in the first time theh traveled together.
The point blue coat reminds me of Maggie Simpson's Star Snow Coat.

So cute! 😍
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❤️ (x)
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I take a trip to the "Hell Fest" with Tony "Candyman" Todd- but is it a journey worth taking? https://mrgordo82.blogspot.com/2019/01/new-review-hell-fest-2018.html
#hell fest#tony todd#amy forsyth#reign edwards#bex taylor klaus#gale anne hurd#gregory plotkin#blair butler#carnival horror#dark ride#funhouse#scarehouse#theme park
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Book recs and more
Documentary: "Heal" on Netflix Podcast: The 3 Day Effect: How Nature Calms Your Brain Books:
-8 Keys to Recovery from an Eating Disorder & Workbook by Carolyn Costin
-The Whole-Brain Child: 12 Revolutionary Strategies to Nurture Your Child's Developing Mind Book and Workbook by Dr. Daniel Siegel
-Recovery 2.0: Overcome Addiction and Thrive by Tommy Rosen
-Sexual Healing: Transforming the Sacred Wound by Peter Levine, PhD
-Nature and The Human Soul: Cultivating Wholeness in a Fragmented World by Bill Plotkin, PhD
-Let Go Now by Karen Casey
-Codependent No More by Melody Beattie
-The Spiritual Dimension of the Enneagram Nine Faces of The Soul by Sandra Maitri
-The Four Agreements by Miguel Ruiz
-Calming the Emotional Storm by Sheri Van Dijik
-Earth Magic by Starhawk
-Code Red: Know your Flow and Unlock your Monthly Superpowers by Lisa Lister
-Why We Sleep: Unlocking the Power of Sleep and Dreams by Matthew Walker, PhD
-Guide to Getting it On! by Paul Joannides PsyD newest edition (10th)
-Wired for Love: How Understanding Your Partner's Brain and Attachment Style Can Help You Diffuse Conflict and Build a Secure Relationship by Stan Tatkin, PsyD
Workbooks:
-The Moontime Harmony Workbook by Donna Wolper
-Seeking Safety: A Treatment Manual for PTST and Substance Abuse by Dr. Lisa Najavits
-The Dialectical Behavior Therapy Skills Workbook by Matthew Mckay, PhD
-Child-Centered Play Therapy Workbook by Dr. Jodi Ann Mullen
-LGBTQ+ Youth: A Guided Workbook to Support Sexual Orientation and Gender Identity by Lee-Anne Gray, PsyD
Children’s books:
-My Body! What I say Goes! by Jayneen Sanders
-Let's Talk about Body Boundaries, Consent and Respect by Jayneen Sanders
-My Body Belongs to Me from my Head to my Toes by Jill Starisehvsky
-I am Human: A Book of Empathy by Susan Verde
-Life by Cynthia Rylant
-I am Enough by Grace Byers
-I'm Going to Like Me by Jamie Lee Curtis
-It Feels Good to be Yourself: A Book about Gender Identity by Theresa Thorn
-Beautiful Oops! by Barney Saltzberg
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Hell Fest (2018)
Genre: Horror
Who’s In It: Amy Forsyth, Reign Edwards, Bex Taylor-Klaus, Christian James, Matt Mercurio, Robbie Attal, Tony Todd
Who Directed It: Gregory Plotkin
Plot: A masked serial killer turns a horror-themed amusement park into his own personal playground, terrorizing a group of friends while the rest of the patrons believe that it is all part of the show.
Running Time: 89 Minutes
IMDB Score: 5.5
Metascore: 26
Rotten Tomatoes Score: Critics 40% Audience 41%
Why I Watched It: Honestly it’s a horror film and a slasher to boot and I’m a sucker for at least a decent slasher film.
How I Watched: Super Chanel in Canada
Random Thoughts: Gale Anne Hurd is one of the producers here. Now it’s nice she’s still working in genre but not great she’s working on stuff like this but I support anyone who at least tries to make good to decent horror films.
It’s kind of funny that even though we haven’t had a new hit in awhile, the slasher genre will not go gently into the goodnight. I think it’s because it’s such a cheap genre to work in, really you need youngish actors and a spooky mask.
What I Liked: I’m so in the middle with this movie I almost don’t have anything super positive or super negative to say and I think that’s because I’m very forgiving of the slasher genre, honestly give me decent acting and a couple of good kills and I’m pretty content. Here in both counts it’s mixed bag. The acting on the whole isn’t bad,mostly good stand-out being Bex Taylor-Klaus who I think is fast becoming a go to genre actor and a good one at that and here she’s the best thing in the movie next to legend Tony Todd but he’s not init much. Taylor-Klaus is having fun and she’s so charismatic and she plays in the horror genre so effortlessly. I wish she was the lead.
The set up is fine but I will say they do get some tension and suspense in the whole amusement park set up it did remind me of Haunt, which is a better movie, but it used it’s set up well and there’s one really good scene in the bathroom that is creepy and very effective.
It moves pretty well I will say it’s one of the few slasher films that doesn’t sag or slow down in the middle this one does a nice job of building to the end and it’s short and that is always a good thing in horror.
What I Didn’t Like: It’s one of those films that just doesn’t stand out, it’s fine and there’s moments but the film as a whole just didn’t grab me, it’s not boring but it’s also not very engrossing. Everything in this film is ok or fine plot wise they pretty much tick off all the boxes and you know what that can work but I think it’s needed more energy and it needed to be more urgent.
Except for Tony Todd( pretty much a cameo) and Taylor-Klaus the acting is alright but the characters are bland, pretty standard and the final girl is just a cookie cutter of a final girl, I couldn’t tell you her name or what she was like.
The only thing I thought was a let down was the kills and the killer, this is one of those films that isn’t a mystery even though the killer wears a mask who it is doesn’t matter and that hurts the film they try at the end to give us something but it’s not enough and the killer himself is boring, nothing stands out about him. The setting has more personality than the killer here. The kills are bland and aren’t memorable at all and you need that for a slasher film. There’s no Holy Shit or WTF moments to hang your hat on.
The ending is fine and I will say this movie didn’t suck but it didn’t stand out either and the ending would have hit harder if the rest of the movie was at that level, the ending felt tacked on.
Final Thoughts: For slasher films this is as middle of the road as you’re going to get, not terrible not great, it’s a movie that’s fine while you watch it and you’ll vaguely remember it in a week or so.
Rating: 5/10
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Hell Fest goes retro with a pair of '80s-style posters above and a tubular new trailer below. The slasher film hits theaters this Friday, September 28, via CBS Films and Lionsgate.
Gregory Plotkin (Paranormal Activity: The Ghost Dimension) directs from a script by Seth M. Sherwood (Leatherface), Blair Butler (Polaroid), and Akela Cooper (Luke Cage). Gale Anne Hurd (The Walking Dead, The Terminator) produces.
Amy Forsyth (Channel Zero), Reign Edwards (The Bold and the Beautiful), Bex Taylor-Klaus (Scream), Christian James, Roby Attal, Matt Mercurio (Sleepy Hollow), and Tony Todd (Candyman) star.
Read on to watch the VHS-inspired trailer.
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College student Natalie (Amy Forsyth) is visiting her childhood best friend Brooke (Reign Edwards) and her roommate Taylor (Bex Taylor-Klaus). If it was any other time of year these three and their boyfriends might be heading to a concert or bar, but it is Halloween which means that like everyone else they will be bound for Hell Fest – a sprawling labyrinth of rides, games, and mazes that travels the country and happens to be in town. Ever year thousands follow Hell Fest to experience fear at the ghoulish carnival of nightmares.
But for one visitor, Hell Fest is not the attraction – it is a hunting ground. An opportunity to slay in plain view of a gawking audience, too caught up in the terrifyingly fun atmosphere to recognize the horrific reality playing out before their eyes. As the body count and frenzied excitement of the crowds continues to rise, he turns his masked face to Natalie, Brooke, Taylor, and their boyfriends who will fight to survive the night.
#hell fest#tony todd#amy forsyth#reign edwards#bex taylor-klaus#roby attal#matt mercurio#gale anne hurd
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We are only days away from Hell Fest arriving in theaters and CBS Films has just released an insanely awesome retro “Throwback Trailer” that makes the film, about a costumed killer terrorizing a theme park during Halloween, look just like one of your favorite classic slashers from the 1980s.
After following the development of this project for years, I couldn’t be more excited to finally see it on the big screen when it premieres at our local theater this Thursday night, and this final trailer is simply glorious.
The official synopsis: A masked killer turns a horror themed amusement park into his own personal playground, terrorizing a group of friends whle the rest of the patrons believe that it is all part of the show.
The film stars Bex Taylor-Klaus (Scream: The TV Series, Arrow), Amy Forsythe, Reign Edwards, Christian James, and genre icon Tony Todd (Candyman, The Crow, Final Destination, Hatchet), directed by Gregory Plotkin (Paranormal Activity: The Ghost Dimension; editor of Get Out, Happy Death Day) and executive produced by Gale Anne Hurd (The Walking Dead).
Hell Fest opens in theaters this Friday, September 28.
You can watch the ’80s throwback trailer for Hell Fest below.
For more Halloween news, follow @HalloweenDaily.
Halloween Slasher 'Hell Fest' Gets '80s Throw Back Trailer We are only days away from Hell Fest arriving in theaters and CBS Films has just released an insanely awesome retro "Throwback Trailer" that makes the film, about a costumed killer terrorizing a theme park during Halloween, look just like one of your favorite classic slashers from the 1980s.
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HELL FEST | Red Band Trailer
CBS Films, “A masked serial killer turns a horror themed amusement park into his own personal playground, terrorizing a group of friends while the rest of the patrons believe that it is all part of the show.
College student NATALIE (Forsyth) is visiting her childhood best friend BROOKE (Edwards) and her roommate TAYLOR (Taylor-Klaus). If it was any other time of year these three and their boyfriends might be heading to a concert or bar, but it is Halloween which means that like everyone else they will be bound for HELL FEST – a sprawling labyrinth of rides, games, and mazes that travels the country and happens to be in town. Every year thousands follow Hell Fest to experience fear at the ghoulish carnival of nightmares.
But for one visitor, Hell Fest is not the attraction – it is a hunting ground. An opportunity to slay in plain view of a gawking audience, too caught up in the terrifyingly fun atmosphere to recognize the horrific reality playing out before their eyes. As the body count and frenzied excitement of the crowds continues to rise, he turns his masked face to NATALIE, BROOKE, TAYLOR and their boyfriends who will fight to survive the night.
A terrifying thrill ride from iconic horror producer Gale Anne Hurd (The Walking Dead, The Terminator) and director Gregory Plotkin (Paranormal Activity: The Ghost Dimension, Editor – Get Out, Happy Death Day), this September, audiences will discover that it’s fun going in… but it’s hell getting out.”
Peace, JW
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CBS Films’ HELL FEST Narrowly Avoids Theatrical Dogfight With New Release Date
Originally set for release October 12, 2018, Hell Fest has been bumped up almost a full calendar month. The Lionsgate and CBS Films production was originally set to compete with Goosebumps: Haunted Halloween, and David Gordon Green’s Halloween the following week. The film is now set to release on September 28, 2018.
Hell Fest is directed by Gregory Plotkin and produced by Gale Anne Hurd. Plotkin previously directed Paranormal Activity: The Ghost Dimension but has also served as editor on several horror films, including Get Out and Happy Death Day. Gale Anne Hurd has served as producer on a laundry-list of your favourite genre films including Aliens and The Terminator, as well as AMC’s The Walking Dead. The experience of these two are sure to make a strong foundation for Hell Fest, if not for a stellar cast that includes Amy Forsyth (Channel Zero), Reign Edwards (The Bold and the Beautiful), and Bex Taylor-Klaus (MTV’s Scream series).
Hellfest centers on three friends, located in a horror theme park. When a killer is on the loose in the park on Halloween, patrons think the murder and mayhem is just part of the show. But our three female leads know better, and will need to fight for their lives as they find themselves stalked by the maniac. Sounds a little familiar to me but also, a whole lot of fun.
Forsyth, Edwards, and Taylor-Klaus all have strong television acting careers, and Hell Fest will be the first horror film with Forsyth, Edwards, and Taylor-Klaus in leading roles. The strong female cast, and the experience of the directing and producing team make sure that Hell Fest is definitely a film to look out for this autumn. Hell Fest opens in theaters on September 28, 2018.
Are you excited for Hell Fest? Lets us know in the comments below, on Twitter, Instagram, Reddit, and in the Horror Fiends of Nightmare on Film Street Facebook group!
The post CBS Films’ HELL FEST Narrowly Avoids Theatrical Dogfight With New Release Date appeared first on Nightmare on Film Street - Horror Movie Podcast, News and Reviews.
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Các giao dịch bất động sản ở Massachusetts cho các quận Hampshire và Franklin, ngày 5 tháng 4 năm 2020 (Biên tập viên Lưu ý: Các hành động của Hạt Hampden không có sẵn vì việc đóng cửa tạm thời Tòa án Roderick L. Ireland ở Springfield vì lo ngại về coronavirus.)AmherstMelanie J. Fletcher-Howell cho Jessica M. Jimison, 15 High Point Drive, 250.000 đô la.Lise N. Halpern và Jeffrey S. Cooley cho Michael W. McClurg và Heather W. McClurg, 22 ngõ ống Ấn Độ, $ 627.000.Các doanh nghiệp lịch sử LLC, đến Daniel R. Friedman và Lara S. Friedman, 22 đường cán dốc, 350.000 đô la.Richard P. Lawlor và Catherine Lawlor cho Joel R. Acker và Tara A. Acker, 36 Weaver Circle, $ 570.000.Ellen Panzer đến Tracy L. Ross, 30 Justice Drive, $ 274.000.Sân vận độngKelly D. McDonald đến Tracey J. Ingebretsen, 308 Buckley Road, 55.000 USD.BelchertownGary K. Gian hàng và Kinda A. Currier đến 67 Dressel Avenue LLC, Phố Dressel, $ 100.Thomas R. Hresko cho Julie A. 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Nông dân, 11 Barnes St., $ 142.000.Heidi Pardee và Jason Pardee đến Adilson Lima Jr., 9 Castle St., 136.000 USD.Rufus G. Chaffee, Rebecca Chaffee và Rebecca Lawrence đến Kaycee E. Partlow, 36 Aspen St., 138.000 USD.Maurice R. Lavallee đến Edward J. Smith, 26 đường Gould, 107.000 đô la.Belco Construction Co Inc., đến CDC Investments Group LLC, Wildflower Drive, 75.000 đô la.Tây thành phốLans G. Christenson, Candice Christenson và Candice Russo đến Kelyn C. Dutkiewicz, Đường Tây Bắc, $ 445.000.WilliamsburgRobert W. Barker và Cynthia C. Barker cho James Dean Paluch và Beth Ann Paluch, 48 South St., $ 624.000.[ad_2] Nguồn
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Goldman Sachs' new managing-director list is out — and it's the largest class in the firm's history (GS)
Bryan Bedder/Getty Images for The New York Times
Goldman Sachs announced its largest-ever class of managing directors.
Of the 509 promoted, 44% are millennials.
The firm announces managing-director promotions every two years.
It's one of the most coveted positions on Wall Street, a step below partner at the premier investment bank.
Goldman Sachs just announced a new class of 509 managing directors — the largest class in the firm's history.
The position is one of the most coveted on Wall Street, one step below partner at the prestigious investment-banking firm. The firm now has 2,148 managing directors, making up 7.1% of the company's workforce.
It's also one of the youngest classes the bank has promoted — 44% are millennials, up from 30% in 2015.
Other headline stats about the class:
66% started their careers as analysts or associates at Goldman Sachs.
24% of the class is women, down from 25% in 2015.
130 were promoted in the securities division, up from 102 in 2015.
101 were promoted in investment banking, up from 97 in 2015.
52 were promoted in technology, up from 38 in 2015.
Eight were promoted in consumer and commercial banking — the division that houses the bank's online-lending business, Marcus — compared with zero in 2015.
Here's the full statement:
The Goldman Sachs Group, Inc. (NYSE: GS) today announced that it has selected a new class of Managing Directors, effective from January 1, 2018, the start of the firm's next fiscal year.
"Our new Managing Directors have demonstrated an outstanding commitment to our people, clients and culture during their tenures at the firm, and we wish them continued success as they take this important next step in their careers," said Lloyd C. Blankfein, Chairman and Chief Executive Officer of Goldman Sachs.
The following individuals have been promoted to Managing Director:
Gregg Abramson Sanjay Acharya Khalid Albdah Amal Alibair Karthikeyan Anbalagan Rolf Andersson Volker Anger Jonathan Armstrong Ken Ashley Lavanya Ashok Sebastian Ayton Jonathan Babkow Julio Badi Amitayush Bahri Soren Balzer Robert Barlick Jr. Philip Barreca Santiago Bau David Bauer Oksana Beard Lee Becker Virender Bedi Stuart Beer Christian Beerli Amanda Beisel Yumiko Bekku David Bell Pierre Benichou Andrew Benito Marco Bensi Laura Benson Stephen Bergin Daniel Berglund Greg Berry Shital Bhatt Dipanjan Bhattacharjee Anu Bhavnani Carissa Biggie Vineet Birman Daniel Bitel Anne Black Richard Blore Emmanuel Bodenstein Timothy Braude Sean Brenan Hugh Briscoe Nathaniel Bristol Leo Brito Troy Broderick Levee Brooks Eric Brothers Robert Bruns III Anthony Bunnell Meg Burke Susan Burt Sean Butkus Russell Byrne Edward Byun Adam Cahill Alessandro Calace Cristiano Camargo Ken Cawley Swapan Chaddha Patrick Chamberlain Richard Chambers Daphne Chan Lily Chan Ben Chance Ginger Chang Vikram Chavali Alex Cheek Jae Joon Choi Ken Choi Paul Choi David Clark Denis Cleary Daniel Cleland-James Ayanna Clunis Pamela Codo-Lotti Jesse Cohen Paul Coles Simon Coombes Jenny Cosco Philip Coureau Nathan Cowen Matthew Cox (Securities) Shaun Cullinan Christine D'Agostino Emile Daher Hiren Dasani Russell Day Pierre De Belen Merche del Valle Caitlin DeSantis Jack Devaney Thomas Devos Mats Dewitte Hristo Dimitrov Tim Dinsdale Isabella Disler Christian Ditullio Terence Doherty Yakut Donat Nicola Dondi Brian Dong Jason D'Silva Stefan Duffner Jane Dunlevie Marie Duval Julien Dyon Rohini Eapen Zach Eckler Sayaka Eda Jason Eisenstadt Chris Emmerson Tiffany Eng Chendan Esvaran Erkko Etula Liz Ewing Michael Fargher Matteo Farina Leigh Farris Sarah Faulkner Tom Favia Brett Feldman Jennifer Feng Jon Ferguson Alex Field Herbert Filho Alex Finston Dean Flanagan Greg Flynn Trip Foley Andrew Ho Kwon Fong Moran Forman Michael Fox Caroline Fraser Daniel Freckleton Tim Freeman Reto Frei Giles French Kirsten Frivold Michael Fu Rob Fuentes Kenji Fujimoto Carrie Gannon Chantal Garcia Akhil Garg Alex Garner Nick Gelber Andrew Gent Gizelle George-Joseph Andrea Gift Sean Gilbride Andreas Glaser Yong Suan Goh Sona Gohel Amir Gold Jeremy Goldstein Steven Gonzalez Jeff Gowen Adam Greene Tom Groothaert Hannes Gsell Ashwin Gupta Ali Haji Ayaz Haji Robert Hamilton Kelly Victoria Hampson Raja Harb Andy Harding Ryan Harster Selma Hassan Stephen Hawinkels Jacqueline Haynes Jason He* Craig Hempstead David Herrmann David Hickey Thomas Hilger Mitch Hochberg Jodi Hochberger Jane Hodges Peter Hodgkinson Dylan Hogarty Tim Holliday Naftali Holtz Amy Hong Jason Hudes Earl Hunt Joseph Hwang Yoshinori Ide Kazuya Iketani Daniel Jackson Ankit Jain (Risk) Gaurav Jaitly Jan Janssen David Jeria Alnawaz Jiwa Kim Johns Scott Johnson Elis Jones Neil Jones Robert Jones Philip Joseph Anand Joshi Shawn Joshi Ritu Kalra Michael Kaprelian Nadeem Kayani Alicia Keenan Neil Kelleher Tom Kennedy Aqil Khan Sarah Kiernan Daniel Kim Eugene Kim (IMD) Jason Kim (GIR) Sora Kim Kristy Kinahan Eugene King Laura Kirk Kunal Kishore Elliot Klapper Jayee Koffey Jason Koon Jennifer Kopylov Daniel Korich Ichiro Kosuge Vladimir Kotlyar Samuel Krasnik Katherine Krause David Kraut Sergey Kraytman Nitin Kulkarni Ram Kulkarni Dileep Kumar (Securities) Santosh Kunnakkat Wendy Kwong JP Lall Bill Lambert David Landman Yi Larson Niccolo Laudiero Nick Laux David Lee Phillip Lee Samuel Lee Shawn Lee Michael Leister David Lerner Naomi Leslie Matt Levine Na Li Haining Liang Nancy Licul Monica Lim Michelle Ling Srujan Linga Philip Linton Alan Liu Daniel Liu Eric Liu Heiman Lo Juan Lorenzo Tian Lu Wayne Lu James Lucas Dennis Luebcke Martin Luehrmann John Lynch Gina Lytle Leo Ma* Caesar Maasry Geoff MacDonald Robert Magnuson Toshiyuki Makabe Mariano Mallol Geydar Mamedov Kara Mangone Donna Mansfield Ajit Marathe Gilberto Marcheggiano James Marchese Michael Marcus Joshua Matheus Ann Mathews Chris Mathie Brian McCallion Graham McClelland Anne McCosker Michael Meehan (Compliance) Taylor Mefford Neil Mehta Adam Meister David Mericle Vitali Meschoulam Eric Meyers Alex Mignotte Andras Mikite Christopher Milligan Rahul Mistry Mike Mitchell Neil Moge Waleed Mohsin Babak Molavi Joel Monson Guy Morgan James Morris Antoine Munfa Aimee Mungovan Yuji Murata Dan Murphy Josh Murray Brian Musto Shehzad Nabi Devarajan Nambakam Ramanathan Narayanan Ganapathy Natarajan Danielle Natoli Murad Nayal Karim Nensi Scott Neu Dennis Ng Ken Ng Benjamin Ngan Joy Nguyen Salman Niaz Anders Nielsen (IMD) Howard Nifoussi Jun Niki Leah Nivison Laura Noble James Nolan Lauren Oakes Lynn Oberschmidt Allison O'Connor John O'Connor Shunil Ohrie Damian Ordish Leke Osinubi David Ossack Sathiya Padmanaban Danielle Pallin Salvador Pareja Dalmir Pasini Clorinda Pasqua Chris Pawson Paris Pender Patrick Perkins Philippe Perzi Wendy Peters Andy Phillips Flavio Picciotto Michael Pieck Sam Pirog Thomas Plank Joseph Plotkin Wade Podlich Ashish Pokharna Caitlin Pollak Charles Pollock Joe Porter Travis Potter Rohit Prabhu Richard Privorotsky Andrew Pucher Jay Rabinowitz Ankit Raj Harsha Rajamani Dmitry Rakhlin Yasser Rathore Edoardo Rava Elizabeth Reed Alexandre Reinert Stephen Reinhard Irfan Rendeci Christian Resch Andrew Rhee Riccardo Riboldi James Rinsler Caroline Riskey Helen Robinson Mark Rosen Amit Roy Joe Ryan Bernhard Rzymelka Takehiro Sakuramoto John Sales Rob Sarazen Vineeta Saxena Dominik Schaefer Andrea Scott Majid Sebti Bipin Sehgal Arseni Seregin Irma Sgarz Paulomi Shah Shreyas Shah Sunny Shah Faisal Shamsee Daniel Shapiro Mahesh Sharma Shripal Sharma Mai Shin Romy Shioda Toshimichi Shirai Mark Short Pankauz Shrestha David Shrimpton Obaid Siddiqui Mike Sidorov Scott Silverglate Stefani Silverstein Amy Silverzweig Jasdeep Singh Gabriella Skirnick Michael Sklow Maxine Sleeper Michael Slomienski Michael Sloyer Nicholas Smith (IBD) Ruth Smithson Christine Smyth Ben Snider Stacy Sonnenberg Cleaver Sower Ro Spaziani Brian Steele Johannes Steffens Duncan Stewart Stephen Stites Laurent Storoni Caroline Styant Joel Sulkes Mancy Sun Winnie Tam Nachiket Tamhane Ken Tang MK Tang Amish Tanna Melissa Teng Ross Tennenbaum Greg Thompson Fiona Thomson Justin Tobe Jason Tofsky Brad Tuthill Masahiro Uchiyama Nehal Udeshi Saad Usmani Meg Vaden Pramod Vaidyanathan Adam Van de Berghe Fred van der Wyck Suzanne van Staveren Andrew Vass Mahesh Vellanki Kadambari Verma Christopher Vilburn Iva Vukina Heng Vuong Ketan Vyas Joe Wall Jeffrey Wang Jiantao Wang Joshua Wang Lily Wang (Technology) Sherry Wang Victoria Ward (Compliance) Jeff Warren Noriko Watanabe Ramey Watkins Sam Watkins Heiko Weber Niki Webster Scott Weinstein Ryan Westmacott James Westwood Keith Wetzel Mark Wetzel James Whittingham Sabine Wick Robert Wieser Devin Wilde David Wilkins John Wilkinson Andrew Williams Ed Wong (IBD Technology) Eric Wong (Internal Audit) Kate Wood Amanda Wu Douglas Wu Joanne Xu Liang Xu** Rupam Yadav Kazushi Yamaguchi Hubert Yang Lisa Yang Basak Yavuz Zeynep Yenel David Yu Brian Zakrocki Thomas Zeppetella Yi Zhang* Adib Zouein Patrik Zumstein Piotr Zurawski Jonathan Zwart
*Employee of Goldman Sachs Gao Hua Securities Company Limited **Employee of Beijing Gao Hua Securities Company Limited
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Harold was a good friend, mentor, advicer and experienced in a lot of subjects. A good guy that gladly helped out. Even to strangers and fans alike.
Good father, even to Mollie as I am sure he tried to work in a father - daughter relationship the best he could. How was he the bad one in this though? He had open relationship with his wife while Heckerling did not. Her hubby was furious at Harold but why not also at his own wife? I mean it takes two to Tango.
Good grandude, absolutely. A shame he only got to meet two before he passed. Going to be a bit sad when his and Erica's first jointly one arrives.
Good Husband, first marriage. At first, sure. Then maybe not, open marriage ok but in the end he left her for another woman (even though the promise was to always come home) which she did not see coming and still loved him. Even though they did not live together a lot. I feel sorry for Anne at times. Must have been harsh years ahead.
Good Husband, second marriage. Yes, it sure seems he finally hit home. True love. Nothing open there. They were together constantly from the start. In hotel, together before moving in in a house. This one ended with Harold's death. Can not even imagine Erica's harsh times ahead there.
Basically things that are none of my business but eh, just some thoughts after a weird day with Anxiety, stomach pains and to top it of with a sleeping pill.
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Horror Film HELLFEST Casts Its 3 Female Stars!
Horror Film HELLFEST Casts Its 3 Female Stars!
CBS Films announced today it has found its three female leads for their upcoming horror film, HELLFEST!
Amy Forsyth (The Path, Rise), Reign Edwards (MacGyver, Snowfall) and Bex Taylor-Klaus (Here And Now, Arrow) have been cast as lead heroines for the film.
Hellfestis set on Halloween night at a horror theme park where a costumed killer begins slaying innocent patrons who believe that it’s all…
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#Amy Forsyth#Bex Taylor-Klaus#CBS Films#Gale Ann Hurd#Gregory Plotkin#Halloween#Hellfest#Reign Edwards
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Respiratory Infections May Drive Puerto Rico’s High Asthma Burden
Early-life respiratory viruses may play an outsize role in Puerto Rico’s sky-high rates of childhood asthma, according to a collaborative study led by researchers from UC San Francisco and the City University of New York (CUNY).
Puerto Ricans have the highest asthma rates in the world, with the disease affecting roughly 14.2 percent of Puerto Ricans at some point in their lives. In contrast, 9.6 percent of African-Americans, 8.2 percent of non-Hispanic whites, and 4.8 percent of Mexican-Americans report that they have experienced asthma at some point in their lives according to data from the U.S. Centers for Disease Control and Prevention. Puerto Ricans are also four times more likely to die of the disease than non-Hispanic whites.
Asthma risk is an interplay of genetic and environmental factors, and researchers have hypothesized that respiratory viruses endemic to the island are a key contributor to Puerto Rico’s high asthma rates.
“The alarmingly high rate of asthma in the Puerto Rican population has been a mystery to scientists since its discovery decades ago,” said Eric M. Wohlford, MD, PhD, a UCSF pediatric allergy and immunology fellow in the Asthma Collaboratory in the UCSF School of Pharmacy, and lead author of the new study. “Our lab and others have previously discovered population-based differences in asthma genetics, response to medications, and environmental factors that may contribute, but there has been an open question as to whether common respiratory viral infections may differentially predispose some groups to asthma more than others.”
The new study, published May 5, 2020, in PLOS ONE, was overseen by corresponding author Luisa Borrell, DDS, PhD, a distinguished professor in CUNY’s Graduate School of Public Health & Health Policy, and senior author Esteban Burchard, MD, MPH, a pulmonologist and professor in the UCSF departments of Medicine and of Bioengineering and Therapeutic Sciences who directs the UCSF Asthma Collaboratory. The work is part of a collaboration with study co-author José R. Rodríguez-Santana, MD, at Centro de Neumologia Pediátrica in Caguas, Puerto Rico, among other collaborators.
The research team collected socio-demographic information and medical histories for 2,842 Puerto Rican, Mexican-American, and African-American children.
Study participants were drawn from the GALA II and SAGE studies, two parallel case-control studies of asthma led by the Burchard lab, which were conducted between 2006 to 2014 in Latino (Mexican-American and Puerto Rican) and African-American children aged 8 to 21, respectively. SAGE participants were recruited from the San Francisco Bay Area and GALA II participants were recruited from across the continental United States (Chicago, Houston, New York City, and the San Francisco Bay Area) and Puerto Rico.
The researchers split the children into 1,091 with an asthma diagnosis and 1,733 without a diagnosis and determined how much more often children with asthma had experienced a handful of common respiratory infections before the age of two – including upper respiratory infection, pneumonia, bronchitis, and bronchiolitis / respiratory syncytial virus (RSV).
The research confirmed the higher rates of early life respiratory infections among Puerto Ricans – finding that rates of early life RSV infections or bronchiolitis in particular were four- to nine-fold higher in Puerto Rican children than in Mexican-Americans and African-American children.
They also showed the consequences of these high rates of early-life infection for later asthma risk were also especially severe in Puerto Rican children.
Compared to children without asthma, Mexican-American children with asthma were three times more likely to have had at least one of a handful of common early life respiratory infections, and African-American children with asthma were four times more likely to have had such an infection, but Puerto Rican children with asthma were more than six times more likely to have had at least one these infections before the age of 2.
“Our results suggest that while all groups have greater odds of asthma after respiratory infections, some groups are more affected than others,” Borrell noted. “Particularly in the Puerto Rican population, we note that viral infections may be a major driver of childhood asthma compared to other groups.”
“Our current study gives us a glimpse at the association between early-life respiratory infections and asthma in Puerto Ricans, but it is not able to establish causation,” Wohlford added. “To do that, longitudinal studies that follow patients over time during and after viral infections to monitor for asthma development are needed. Our group is actively enrolling a large longitudinal birth cohort study of 3,000 Puerto Rican mother��infant pairs, called PRIMERO, to do exactly that.”
PRIMERO, Puerto Rican Infant Metagenomic and Epidemiologic Study of Respiratory Outcomes, is an NIH/NHLBI funded longitudinal birth cohort designed to study respiratory viral infections and early life origins of asthma.
Authors: Additional authors on the study were Jennifer R. Elhawary, Brian Plotkin, Sam Oh, Thomas Nuckton, Celeste Eng, and Sandra Salazar of UCSF; Michael LeNoir of Bay Area Pediatrics; Kelley Meade of UCSF Benioff Children’s Hospital Oakland; Harold J. Farber of Baylor College of Medicine and Texas Children’s Hospital in Houston; Denise Serebrisky of Jacobi Medical Center in the Bronx; Emerita Brigino-Buenaventura of Kaiser Permanente-Vallejo Medical Center; William Rodriguez-Cintron of Veterans Caribbean Health Care System in San Juan, Puerto Rico; Rajesh Kumar of The Ann and Robert H. Lurie Children’s Hospital of Chicago; Shannon Thyne of UCLA; and Max A. Seibold of National Jewish Health in Denver.
Funding: This work was supported in part by the Sandler Family Foundation, the American Asthma Foundation, the RWJF Amos Medical Faculty Development Program, Harry Wm. and Diana V. Hind Distinguished Professor in Pharmaceutical Sciences II, National Institutes of Health (NIH) (R01HL117004, R01HL128439, R01HL135156, 1X01HL134589, R01HL141992, 5T32GM007546, 1U01HL138626-01A1), National Institute of Health and Environmental Health Sciences (R01ES015794, R21ES24844), the National Institute on Minority Health and Health Disparities (P60MD006902 RL5GM118984, R01MD010443) and the Tobacco-Related Disease Research Program (24RT-0025, 27IR-0030).
Disclosures: The authors declare that they have no relevant conflicts of interest.
source https://scienceblog.com/516155/respiratory-infections-may-drive-puerto-ricos-high-asthma-burden/
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