#AAA Washington

[futurelabs]

Ohh, a sleepover! C-Can we order pizza? 🤡🔪📹

[nando161mando]

Now we know how much it costs to make a $2,800 Dior bag

[heart-forge]

Less of an ask here, more of a statement!

The first time I'd ever heard of poutine was when playing Bad Ritual for the first time a few years ago. I looked it up and it sounded absolutely amazing. Flash forward to the state fair (not even in a northern state, we're talking Carolinas baby!) back in October, and to my surprise, they actually had some at the beef stalls! And it was so fucking good! I keep wanting craving poutine now, and every time I do I think of Bad Ritual :)

I think it's SO WILD that America hasn't en masse adopted it. Cheese curds and gravy on fries? Like? Lord! And listen people bully online chefs for not making them correctly and they're valid because famous Americans barely consider Canada a country let alone somewhere distinct from them, but while I will be annoyed every time an American chef is like "well I couldn't find cheese curds so I'm just using Kraft singles" or something stupid (mostly because these are the same people sourcing rattlesnake meat and a rare flower that only blooms on a certain road in China at night when it rains during a full moon, but yeah, cheese curds are too hard 🙄🙄🙄), technically there's no wrong way to do it. It's ubiquitous here but like in high school my cafeteria would give us shredded mozz and dark gravy on fries and that's like, close enough given their budget and time crunch.

Plus you can put stuff on it !! We have an entire restaurant dedicated to putting stuff on it (which listen is it gross? yes. did I help my college friend steal a two pound poutine from them? also yes) so I also hate when the online chefs act like "ik you'll hate me if I put something on it" like girl I was in Quebec getting MSM poutines like it's not that deep.

Anyway I have a lot of feelings about poutine and Canadian food in general. I used to follow so many internet chefs and then had to slowly weed them out, frequently for a variety of reasons but also I don't think it's a coincidence that at this point the only proper food channel that I follow is Sorted, which listen, they're British so it's not more diverse, but they're just not as snobby. I'm glad you think of BR when you infrequently get poutine 😂😂 and glad that I didn't think twice about what kind of food the agent was getting after all was said.

[godmodebeginswithlesbians]

well shits about to go down with hockey once THIS becomes known

[joegeniusblog]

PASSING/MLB: Johnny Jeter

Johnny Jeter passed away on January 16th. of this year. This flew under the radar of the national media and even my brother and sister MLB nerds over at Baseball Fever didn’t find out until July of the passing of Mr. Jeter who passed of undisclosed causes in his native Louisiana where he had attended Grambling University. Baseball was the thread in the fabric of this 12 year-olds summer of…

[moneeb0930]

𝗦𝗛𝗜𝗥𝗟𝗘𝗬 𝗔𝗡𝗡 𝗝𝗔𝗖𝗞𝗦𝗢𝗡 (1946- )

Shirley Ann Jackson, born in 1946 in Washington, D.C., has achieved numerous firsts for African American women. She was the first black woman to earn a Ph.D. from Massachusetts Institute of Technology (M.I.T.); to receive a Ph.D. in theoretical solid state physics; to be elected president and then chairman of the board of the American Association for the Advancement of Science (AAAS); to be president of a major research university, Rensselaer Polytechnic Institute in New York; and to be elected to the National Academy of Engineering. Jackson was also both the first African American and the first woman to chair the U.S. Nuclear Regulatory Commission.

Jackson’s parents and teachers recognized her natural talent for science and nurtured her interest from a young age. In 1964, after graduating as valedictorian from her high school, Jackson was accepted at M.I.T., where she was one of very few women and even fewer black students. Despite discouraging remarks from her professors about the appropriateness of science for a black woman, she chose to major in physics and earned her B.S. in 1968. Jackson continued at M.I.T. for graduate school, studying under the first black physics professor in her department, James Young. In 1973, she earned her Ph.D.

Shirley Jackson completed several years of postdoctoral research at various laboratories, such as Fermi in Illinois, before being hired by AT&T Bell Laboratories in 1976, where she worked for 15 years. She conducted research on the optical and electronic properties of layered materials, surface electrons of liquid helium films, strained-layer semiconductor superlattices, and most notably, the polaronic aspects of electrons in two-dimensional systems. She is considered a leading developer of Caller ID and Call Waiting on telephones.

After teaching at Rutgers University from 1991-1995, Jackson was appointed chair of the U.S. Nuclear Regulatory Commission by Bill Clinton. In 1999, Jackson became President of Rensselaer Polytechnic Institute, where she still serves today. In 2004, she was elected president of AAAS and in 2005 she served as chairman of the board for the Society. Dr. Shirley Jackson is married to a physicist and has one son.

[computertranny]

george washington burning in hell impressjon:: AAAAAAAAAAAA‼️‼️‼️ AAAAAAAAAA AAA AAAAAAAA‼️‼️AAAAAAAAAAAA‼️

[misschf-aisa]

I have an epic tale that is my day yesterday. I think it would be good for me to write it all out as if someone was going to read it, but in a place where it will be lost as soon as I post it. Tumblr is the perfect black hole for this space shot.

I should provide context, but it would only make the story longer and I just don’t have the energy. Okay, maybe a little.

Friday my dad, who is 78, said he’d gotten a voicemail, his oncologist wanted to see him for a checkup at noon Monday. Bad weather was in the forecast for Monday morning, but weathermen are notoriously unreliable so I just said something about if it’s icy you’ll have to reschedule. He was like, of course, and we went about our lives.

Today is Monday and I woke up to a world covered in a good quarter inch of ice. Nothing awful, we didn’t lose power, just enough to make the dog not want to go outside to do her business. (I made her go outside against her wishes, for which I was glared at while she crouched and pooped, but it wasn’t in the house.)

It crossed my mind to check in with dad, but no one would go out in this weather, right? Yeah, you see where this is going.

I got a text around noon. Dad had skidded into a ditch and couldn’t get the car out. Help. I ground my teeth a little, but managed to refrain from texting questions about what the hell he was doing in his car on a day like today. That wouldn’t be helpful, especially after he said it had really scared him. So okay. I glance out the window and my little Fiat is encased in ice. Dad never really fit comfortably in it anyhow. I call my oldest son who just moved to town from Washington state after mustering out of the Navy. He says his 4WD truck is in the garage and he’ll come pick me up.

Oh, I forgot. I have to go because I’m the one with the AAA (thanks @l82theparty) and I’ll need to show them my card before they’ll pull him out of the ditch.

Hey, it would be smart to call AAA now and get the ball rolling since there are probably a shit ton of people in ditches today. So I call dad for a more specific location so I can tell AAA where to find him. He says his GPS just keeps giving him the street number, which is one I don’t recognize. Can he give me a cross street? No. Can he give me a landmark? The route between his house and the doctor’s office is pretty easy to recognize, we’ve done it a thousand times for two rounds of chemo and one round of radiation. No landmarks, just this street number. Okay, we’ll try sharing his location. Nope, that is way too technologically advanced. On the up side it killed time until my son showed up in his truck to collect me.

Some more questions with dad on the phone and we’re still no closer to understanding where he is. So I plug the street into the map just to get an idea and that’s when things begin to go sideways. This street shows up outside of town. Way outside of town. It’s between towns so that I can’t even tell you which little town it’s close to because it’s really just not. We follow the bouncing ball down the highway, past the casino on the outskirts of town, past the toll road, out to a place we’ve never heard of. It took us an hour to get this far, for the record.

I’ve decided my GPS has screwed us so I call dad again, confident we’re going to have to go back into town and comb the streets between the cancer center and dad’s house. But I ask him about the landscape he’s in, and he’s confirming everything sounds right. We drive up and down scary hills covered in ice, then some twisting roads also covered in ice, and Dad is on the phone saying that totally sounds right. To my son’s credit the truck only slipped on these roads a couple of times while he gritted his teeth and complained that he should have put something heavy in the truck bed.

We pass a dead end sign, and Dad doesn’t remember seeing one of those. I’m starting to believe we’re fucked. We pass another sign that says no outlet, and dad doesn’t remember it. My son gives me a look, and I shrug. Then we hit a patch of road that is a skating rink and the kid manages to slide himself onto a patch of grass as we both stare at my father’s car at the bottom of this icy hill in the middle of fucking nowhere. At least we found him, right?

Son and I slip and slide on foot down to the car where dad is fine, he’s got the heater on and the radio, just feels foolish and can’t get out because there’s a tree against the driver’s door. Because, dear reader who has made it this far, he’s not in a ditch. He skidded onto the side of the road where the land drops off into a ravine that was maybe 50 feet deep? I can’t say for sure because when I looked at his front tire and how close it was to the drop off it looked more like the Grand Canyon to me.

Okay dad, we’re not going to touch the car. You’re safe, don’t jostle yourself too much, I’m calling 911 for the first time in my life.

(Why is he in BFE? Oh, sorry, that’s Butt Fucking Egypt if you’re from around here. And I still don’t have an answer for that one.)

Meanwhile I look at the icy incline behind us and tell my son no tow truck is ever going to make it down that hill. A nice young Wagoner County Sheriff’s deputy shows up and his answer is to call a wrecker. I mention that no tow truck is ever going to make it down that hill and he gives me a look so I carefully inched my way back up the hill to sit in my son’s truck and wait.

About 20 minutes later it started to rain. About 30 minutes later it’s raining hard. Still raining hard another half hour or so later when the tow truck arrives on the scene.

Would you believe the tow truck driver said his boss won’t let him take his truck down that hill? He says he wouldn’t leave a person down there though (damn human of him) and the deputy, my son, and the tow truck driver trek down to Save Dad.

I watch from the top of the hill because they don’t need any women down there spouting truths and whatnot and getting in the way. I watch them pop the trunk and get my dad’s walker out. I’m standing in the pouring (so cold) rain watching through a layer of fog that has developed as shadowy figures hunch around the two open doors on the passenger side, I’m assuming they’re figuring out how to get dad out of the car on this side.

I can’t see, so I move over and step into a puddle of ice cold water. It’s not really integral to the story, except I was expecting to be pulling dad out of a suburban drainage ditch so I wore the wrong shoes. My nylon running shoes and my wonderful thick warm socks sucked up that icy water and held it like a lover. It was like the opposite of napalm; instead of fire sticking to my body it was ice cold water.

Meanwhile the boys have come far enough up the hill I can see they have dad sitting on the little bench on the walker and my son is walking backwards pulling it while the deputy and tow truck driver are each pushing a handlebar. My son falls down once, then gets up again. I’m not sure how, but they all manage to get back up that hill and get dad in the truck. It doesn’t matter in the grand scheme of things but now I know exactly how much cold rain is required to saturate my rain resistant coat.

The story ends with my son managing to get the truck turned around and safely off of the ice sheet it was resting on. We’re all home and dry and safe and warm. My girl cooked me dinner and made me a hot toddy and snuggled me in warm clothes and an electric blanket. Dad’s car has probably depleted its battery by now because we were all three sitting in the truck when my son asked if he should try to walk back down and turn off the hazard lights. We left it.

So, how was your day?

[lboogie1906]

Dr. Shirley Ann Jackson (August 5, 1946) is a Physicist, born in DC. She has achieved numerous firsts for African American women. She was the first African woman to earn a Ph.D. from MIT; to receive a Ph.D. in theoretical solid state physics; to be elected president and then chairman of the board of the American Association for the Advancement of Science; to be president of a major research university, Rensselaer Polytechnic Institute; and to be elected to the National Academy of Engineering. She was both the first African American and the first woman to chair the US Nuclear Regulatory Commission.

She was accepted at MIT, where she was one of the very few women and even fewer African Americans. Despite discouraging remarks from her professors about the appropriateness of science for an African American woman, she chose to major in Physics and earned her BS. She continued at MIT for graduate school, studying under the first African American Physics professor in her department, James Young. She earned her Ph.D.

She completed several years of postdoctoral research at various laboratories, such as Fermi in Illinois, before being hired by AT&T Bell Laboratories, where she worked for 15 years. She researched the optical and electronic properties of layered materials, surface electrons of liquid helium films, strained-layer semiconductor superlattices, and most notably, the polaronic aspects of electrons in two-dimensional systems. She is considered a leading developer of Caller ID and Call Waiting on telephones.

After teaching at Rutgers University, she was appointed chair of the US Nuclear Regulatory Commission by Bill Clinton. She became President of Rensselaer Polytechnic Institute, where she still serves today. She was elected president of AAAS and she served as chairman of the board for the Society. She is married to a physicist Morris A Washington and has one son. #africanhistory365 #africanexcellence #deltasigmatheta

[youredreamingofroo]

Alright for the oc questions, you can choose who each one is for whether it’s Roo or Leo or someone else! But I thought these might be fun to answer!

💍 RING — does your oc have any piercings? do they want any (more) piercings?

🍎 RED APPLE — where was your oc born? do they still live in/around their place of birth or do they live somewhere else? how do they feel about their birthplace?

🤍 WHITE HEART — what are three of your oc's neutral/questionable traits?

AAA DAZEY TY!! Usually I just default to Roo when I do these (if an oc isn't specified), so I'll do Roo AND an extra oc if I can think of an answer for them :))

questions from this post/rb

[ under the cut due to length :) ]

💍 RING — does your oc have any piercings? do they want any (more) piercings? Roo does NOT have piercings! He's too much of a pussy to get piercings LMAO I don't blame him 🫂🫂

Hero, as you can see, has a lot of piercings LMAO (or ~sort of~ see idk), she has 8 piercings, 3 nose piercings, 2 ear piercings, and 3 lip piercings. Hero is currently satisfied with the amount of piercings she has, but if she WERE or WANTED to get another piercing, it would either be dimple piercings or the piercings u get under ur eye (i dont remember the name >:T)

🍎 RED APPLE — where was your oc born? do they still live in/around their place of birth or do they live somewhere else? how do they feel about their birthplace? Roo was born in Gothenburg, Sweden, but was swiftly moved to Washington, USA, this was around the peak of Virginia's (his mother) depression, so she [Virginia] was VERY prone to making irrational decisions, one of which is moving entire countries... anyways, I digress. Roo, obvs, doesn't live near his birth place anymore, he still resides in WA (where? I have not solidly decided :)), and due to funds, he does not plan to move back anytime soon, but he absolutely LOVESSS his birthplace and Sweden overall c: So unsurprisingly, he really wants to move back to Sweden (esp to see his little sister Deliahna)

Leo was born in Carmarthenshire, Wales, grew up in Carmar., Wales, and around when he was 18-19 years old, he moved to Luverne, Minnesota, sooo obvs, he doesn't live near where he was born LMAO Leo will often scowl and have a bitter taste on his tongue when he hears people talk about Wales, this is mostly due to his mental connection of Wales = His Parents, of whom he wants nothing to do with them :)

(^^ This question took me forever because I had to do research on regional accents and stuff so that I wasn't just spewing nonsense and nothingness for future references ajshjhdskj)

🤍 WHITE HEART — what are three of your oc's neutral/questionable traits?

3 of Roo's Neutral/Questionable traits: His Clinginess/Obsession- I consider this trait a very hit or miss trait, or in this case, questionable, due to the fact that his clinginess/obsessiveness is NOT apparent at first, and upon getting to know him more, his clinginess will show through more, but it becomes questionable when he starts to take interest in someone... he becomes obsessive out of nowhere, and it makes you wonder where on EARTH that came from, but it derives from his clinginess, it's kind of like a pokemon evolution... Attraction -> Clinginess -> Obsession... His silence- Roo tends to be very quiet, that's... that's kind of it LMAO There's really nothing questionable about it, it's just a neutral trait for him His humor- A questionable trait, as he uses humor a lot to cope and avoid answering serious questions (" are you doing okay? " " Who's okay and why am I doing them? " ykyk KDSAJKDAJKD), albeit a very socially acceptable trait, its undeniable that it's still. questionable. especially when the source material is his own trauma-

(^ I was gonna write more for this question but my brain genuinely fried typing this- it makes me so sad that my brain stopped working and I would put posting this off but I reallyyy wanted to answer this so KSJHSJKJ 😭 Im sorry- also hence why there's not a second character..)

[ridenwithbiden]

LAS VEGAS (KLAS) — Nevada Democratic Sen. Jacky Rosen is pushing for the federal government to investigate how big oil companies are merging and reducing competition.

In a letter to the Federal Trade Commission, Rosen and 22 other Senate Democrats asked for a closer look at two planned mergers: ExxonMobil’s acquisition of Pioneer Natural Resources for $60 billion and Chevon’s purchase of Hess Corporation for $53 billion, her office said.

Less competition negatively affects consumers and drives up prices, Rosen said, adding she and her colleagues in the U.S. Senate can try to hold companies accountable.

“By allowing Exxon and Chevron to further integrate their extensive operations into important oil-and-gas fields, these deals are likely to harm competition, risking increased consumer prices and reduced output throughout the United States,” the letter said.

The U.S. average for a gallon of regular was $3.25 as of Wednesday, according to AAA. The average in Nevada was almost $1 higher at $4.17 – about 50 cents lower than this time last year and the fourth highest average after California, Hawaii and Washington State.

Amid record high gas prices last year, Chevon, ConocoPhillips, Exxon and Shell all reported record profits with more than $1 trillion in sales, CBS News reported.

[emma-dennehy-presents]

Celebrating Black Queer Icons

Kye Allums

Born October 23, 1989, Allums is a trans advocate, public speaker, writer, artist, and mentor. In 2010 Allums made history when he became the first openly trans athlete in top tier collegiate sports, in the US. Allums played for George Washington University's Division-I Women's Basketball team for 3 seasons. (Career stats can be found here https://gwsports.com/roster.aspx?rp_id=3125) Allums has said that his coach and teammates were very supportive, and that despite stress from heavy media attention, his transition process was a mostly positive affair. Allums left the team after the 2010-2011 season and graduated from GW in 2011 with a Bachelor's in Fine Arts. Allums has since gone on to become a notable public speaker and trans advocate. Allums travels to high schools, universities, and colleges to speak on his experiences as a trans man and give advice on confronting bullies, as a trans person in academic spaces. Allums has interviewed with a variety of publications over the years including Time, GLAAD, and Playboy. Allums produced the I Am Enough project, to share trans stories and encourage others to submit their own, letting trans people everywhere know they are not alone in their experiences. Allums was one of seven trans people featured in Laverne Cox's MTV Documentary "The T Word" and also appeared in the Netflix Domentary "GameFace". Allums also authored a short text called "Who Am I?", a collection of poems and letters addressing his experiences as a trans man and his relationship with his mother. In 2015 Allums was inducted into the National Gay and Lesbian Sports Hall of Fame. Though largely out of the public eye since the late the 2010s, Allums continues to be an inspiration and role model to many.

Not sure who I will be covering next. Miss Major Griffith-Gracy and Victor J Mukasa are both near the top of the list right now. Willmer Broadnax is still on the table as well, and I may have some sourcing help on that thanks to the other mods @transunity. My content maps are like that of a AAA game publisher's though, and should be read with utter skepticism until they materialize. As always, corrections and suggestions are welcome and wanted!

[c19library]

Known COVID-19 Health Complications

Last Updated September 8, 2023

Repeat Infections

Summary: Repeat infections, even if mild during the acute phase, cause cumulative damage to the body and increase your risk of developing health complications or Long COVID. You should aim to limit the number of times you are infected as much as possible, even if you are not currently high risk (Note: Health complications post-COVID-19 infection can make you high risk) and have been vaccinated.

Published Research

Acute and postacute sequelae associated with SARS-CoV-2 reinfection | Nature Medicine Bowe, B., Xie, Y, & Al-Aly, Z. (2022).

Articles & Reports

Repeat COVID-19 infections increase risk of organ failure, death – Washington University School of Medicine in St. Louis (wustl.edu) Sauerwein, K. (2022).

Why Getting COVID-19 Multiple Times Is Risky For Your Health | Time Park, A. (2022).

Heart & Cardiovascular Damage

Summary: COVID-19 increases your risk of heart failure, heart attacks, strokes, pulmonary embolism, palpitations, arrhythmia, myocarditis, blood clots (thrombosis), etc. post-infection. Inflammation during the acute phase of a COVID-19 infection can damage the heart and blood vessels.

“Risks and 12-month burdens of incident post-acute COVID-19 cardiovascular outcomes in participants without any history of cardiovascular outcomes prior to COVID-19 exposure compared to the contemporary control cohort.” (Xie et al., 2022)

Published Research

Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts | Science Translational Medicine Guarnieri, J. W., Dybas, J. M., ... Wallace, D. C. (2023).

Long-term cardiovascular outcomes of COVID-19 - PMC (nih.gov) Xie, Y., Xu, E., Bowe, B., & Al-Aly, Z. (2022).

Articles & Reports

Blood Clotting Proteins Might Help Predict Long COVID Brain Fog - Scientific American Reardon, S. (2023, September 1).

SARS-CoV-2 can damage mitochondrion in heart, other organs, study finds | CIDRAP (umn.edu) Van Beusekom, M. (2023, August 9).

Your vascular system and COVID | Heart and Stroke Foundation Heart and Stroke Foundation. (2023).

COVID, heart disease and stroke | Heart and Stroke Foundation Heart and Stroke Foundation. (2023, April 17).

How does coronavirus affect your heart? - BHF British Heart Foundation. (2023, March 21).

COVID-19 and Heart Damage: What You Should Know (clevelandclinic.org) Cleveland Clinic. (2022, May 10).

Heart Problems after COVID-19 | Johns Hopkins Medicine Post, W. S., & Gilotra, N. A. (2022).

COVID and the Heart: It Spares No One | Johns Hopkins | Bloomberg School of Public Health (jhu.edu) Desmon, S., & Al-Aly, Z. (2022, March 14).

COVID-19 takes serious toll on heart health—a full year after recovery | Science | AAAS Wadman, M. (2022, February 9).

Brain & Neurological Damage

Summary: COVID-19 infection increases your risk of developing cognitive impairments, mental health issues, poor memory, early onset dementia, and permanent loss of smell due to brain damage and the atrophy of brain matter. "Brain fog" and problems concentrating are common complaints post-infection that have also been linked to brain damage. Damage to blood vessels due to inflammation during the infection may be responsible for this by restricting oxygen flow to the brain. COVID-19 may also directly infect the brain.

Published Research

Biology | Free Full-Text | Vascular Dysfunctions Contribute to the Long-Term Cognitive Deficits Following COVID-19 (mdpi.com) Shabani, Z., Liu, J., & Su, H. (2023).

Frontiers | COVCOG 2: Cognitive and Memory Deficits in Long COVID: A Second Publication From the COVID and Cognition Study (frontiersin.org) Guo, P., Ballesteros, B. A., Yeung, S. P., Liu, R., Saha, A., Curtis, L., Kaser, M., Haggard, M. P., & Cheke, L. G. (2022).

COVID-19 and cognitive impairment: neuroinvasive and blood‒brain barrier dysfunction - PMC (nih.gov) Chen, Y., Yang, W., Chen, F., & Cui, L. (2022).

Comparison of post-COVID depression and major depressive disorder | medRxiv Perlis, R. H., Santillana, M., Ognyanova, K., Green, J., Druckman, J., Lazer, D., & Baum, M. A. (2021).

Articles & Reports

Long COVID May Impair Memory, Cognition for Months (healthline.com) Rossiaky, D. (2022).

COVID Variants Can Affect the Brain in Different Ways - Neuroscience News (2023).

The hidden long-term cognitive effects of COVID-19 - Harvard Health Budson, A. E. (2021). Harvard Medical School.

Long Covid: Even mild Covid is linked to damage to the brain months after infection (nbcnews.com) Ryan, B. (2022). NBC News.

COVID-19 Can Affect the Brain Even Long After an Infection | Time Ducharme, J. (2023). Time.

Lung Damage

Summary: COVID-19 infections can cause lung damage or scarring, and can trigger pneumonia, bronchitis, ARDS, and sepsis. Additionally, some people experience shortness of breath (dyspnea) and difficulty exercising as a post-acute sequela after infection, or multiple infections.

Published Research

At a crossroads: COVID-19 recovery and the risk of pulmonary vascular disease - PMC (nih.gov) Cascino, T. M., Desai, A. A., & Kanthi, Y. (2021).

[Pulmonary manifestations in long COVID] - PubMed (nih.gov) Sommer, N., & Schmeck, B. (2022).

Residual Lung Abnormalities after COVID-19 Hospitalization: Interim Analysis of the UKILD Post-COVID-19 Study - PubMed (nih.gov) Stewart, I., Jacob, J., George, P. M., Molyneaux, P. L., Porter, J. C., Allen, R. J., Aslani, S., Baillie, J. K., Barratt, S. L., Beirne, P., Bianchi, S. M., Blaikley, J. F., ...Jenkins, G. R. (2023).

Articles & Reports

Even mild cases of COVID-19 may cause long-term lung damage - UPI.com HealthDay News. (2022). United Press International.

COVID-19 Lung Damage | Johns Hopkins Medicine Galiatsatos, P. (2022).

Immune System & Autoimmune Diseases

Summary: COVID-19 infection can impair the functioning of your immune system. This means that those who have previously been infected are potentially immunocompromised (higher risk). For some people, the way COVID-19 impairs their immune system results in the onset of autoimmune diseases.

“Elevated levels of proinflammatory cytokines that persist more than 8 months following convalescence.” (Phetsouphanh et al., 2022)

“Crude incidence of each autoimmune disease by COVID-19 and non-COVID groups.” (Peng et al., 2023)

Published Research

Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection | Nature Immunology Phetsouphanh, C., Darley, D. R., Wilson, D. B., Howe, A., Munier, M. L., Patel, S. K., Juno, J. A., Burrell, L. M., Kent, S. J., Dore, G. J., ... & Matthews, G. V. (2022).

Long-term perturbation of the peripheral immune system months after SARS-CoV-2 infection | BMC Medicine | Full Text (biomedcentral.com) Ryan, F. J., Hope, C. M., Masavuli, M. G., Lynn, M. A., Mekonnen, Z. A., Yeow, A. E. L., Garcia-Valtanen, P., Al-Delfi, Z., Gummow, J., Furguson, C., ... Lynn, D. J. (2022).

Risk of autoimmune diseases following COVID-19 and the potential protective effect from vaccination: a population-based cohort study - eClinicalMedicine (thelancet.com) Peng, K., Li, X., Yang, D., Chan, S. C. W., Zhou, J., & Wan, E. Y. F. (2023).

Long-term perturbation of the peripheral immune system months after SARS-CoV-2 infection | BMC Medicine | Full Text (biomedcentral.com) Winheim, E., Rinke, L., Lutz, K., Reischer, A., Leutbecher, A., Wolfram, L., Rausch, L., Kranich, J., Wratil, P. R., Huber, J. E., Baumjohann, D., ... Krug, A. B. (2021).

Articles & Reports

How COVID-19 Changes the Immune System | Time Park, A. (2023, August 18).

How COVID-19 alters the immune system -- ScienceDaily ScienceDaily. (2021, October 28).

Impacts of COVID on the immune system (medicalxpress.com) Herrero, L. (2022, September 19).

COVID-19's impact on the immune system, and how this may affect subsequent infections - ABC News Smith, B. (2022, December 1).

COVID-19 can derange immune system; survivors have autoimmune diseases (usatoday.com) Szabo, L. (2021, March 2).

Long COVID & PASC

Summary: Long COVID is an umbrella term that refers to the onset of disabling symptoms/conditions resulting from any of the previously mentioned organ, immune system, and vascular damage sustained during infection. These conditions are also referred to as "post-acute sequelae of COVID-19" (PASC). Vaccination can reduce the damage experienced by decreasing inflammation during an infection, but Long COVID/PASC can affect anyone. This is especially true in the case of multiple infections. Your risk of developing Long COVID, or worse/new symptoms, increases with each additional infection.

“Cumulative incidence and DALYs of postacute sequelae overall and by organ system at 2 years after infection.” (Bowe et al., 2023)

Published Research

T cell apoptosis characterizes severe Covid-19 disease - PubMed (nih.gov) André, S., Picard, M., Cezar, R., Roux-Dalvai, F., Alleaume-Butaux, A., Soundaramourty, C., Cruz, A. S., Mendes-Frias, A., Gotti, C., … Estaquier, J. (2022).

SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC) | Nature Immunology Proal, A. D., VanElzakker, M. B., Aleman, S., Bach, K., Boribong, B. P., Buggert, M., Cherry, S., Chertow, D. S., Davies, H. E., Dupont, C. L., ... Wherry, E. J. (2023).

The immunology of long COVID | Nature Reviews Immunology Altmann, D. M., Whettlock, E. M., Liu, S., Arachchillage, D. J., & Boyton, R. J. (2023).

Long COVID: major findings, mechanisms and recommendations | Nature Reviews Microbiology Davis, H. E., McCorkell, L., Vogel, J. M., & Topol, E. J. (2023).

Long COVID prevalence and impact on quality of life 2 years after acute COVID-19 | Scientific Reports (nature.com) Kim, Y., Bae, S., Chang, H., & Kim, S. (2023).

Postacute sequelae of COVID-19 at 2 years | Nature Medicine Bowe, B., Xie, Y., & Al-Aly, Z. (2023).

Articles & Reports

Long COVID | NIH COVID-19 Research National Institutes of Health. (2023, June 8).

Long COVID or Post-COVID Conditions | CDC Centers for Disease Control and Prevention. (2023, July 20).

The Most Important Question About Long COVID | Harvard Medical School Pesheva, K. (2023, August 9).

Nearly One in Five American Adults Who Have Had COVID-19 Still Have "Long COVID" (cdc.gov) Centers for Disease Control and Prevention. (2022, June 22).

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Friday, May 26, 2023

Expect big crowds for the summer travel season—and big prices, too (AP) The unofficial start of the summer travel season is here. The number of people going through U.S. airports hit pandemic-era highs last weekend, and those records are almost certain to be broken over the Memorial Day holiday. AAA predicts that 37 million Americans will drive at least 50 miles (80 kilometers) from home this weekend, an increase of more than 2 million from Memorial Day last year. With more travel comes more expense. The average rate for a U.S. hotel room last week was $157 a night, up from $150 in the same week last year, according to hotel data provider STR. And the average daily rate for other short-term rentals such as Airbnb and Vrbo rose to $316 last month, up 1.4% from a year ago, according to AirDNA, which tracks the industry.

DeSantis Declares (1440) Florida Gov. Ron DeSantis (R) made his long-anticipated jump into the 2024 presidential race yesterday, making the announcement in a livestreamed conversation with Twitter CEO Elon Musk. DeSantis has positioned his campaign as focused on conservative populism with an emphasis on effective governing and joins a field of seven other candidates seeking the Republican nomination.

ChatGPT maker OpenAI calls for AI regulation, warning of ‘existential risk’ (Washington Post) The leaders of OpenAI, the creator of viral chatbot ChatGPT, are calling for the regulation of “superintelligence” and artificial intelligence systems, suggesting an equivalent to the world’s nuclear watchdog would help reduce the “existential risk” posed by the technology. In a statement published on the company website this week, co-founders Greg Brockman and Ilya Sutskever, as well as CEO Sam Altman, argued that an international regulator would eventually become necessary to “inspect systems, require audits, test for compliance with safety standards, (and) place restrictions on degrees of deployment and levels of security.” They made a comparison with nuclear energy as another example of a technology with the “possibility of existential risk,” raising the need for an authority similar in nature to the International Atomic Energy Agency (IAEA), the world’s nuclear watchdog. The OpenAI team wrote, “In terms of both potential upsides and downsides, superintelligence will be more powerful than other technologies humanity has had to contend with in the past. We can have a dramatically more prosperous future; but we have to manage risk to get there.”

Fuel shortages slam Cuba’s countryside (AP) Rosa López, a 59-year-old housewife, lit a charcoal stove to boil sweet potatoes and prepare scrambled eggs for her grandchildren. The gas cylinders she normally uses to cook her meals have not been available for almost two months in Mariel, a port town west of Havana. Not far from there, on the highway to Pinar del Río and under a scorching sun, Ramón Victores spent one week waiting in line at a gas station, hoping to fuel up the 1952 red Chevrolet he uses for work, moving produce from one town to another. Cuba’s most recent fuel shortage has crippled an already fragile economy, but it is hitting rural villages particularly hard, with residents resorting to coal fires to cook their food, scrambling to find transport to take them to work and spending days—and nights—at the gas station waiting to fuel up. With food and medications already in short supply amid an economy that was severely hurt by the COVID-19 pandemic, the end of the country’s two-currency system and a tightening of U.S. sanctions, the lack of fuel and cooking gas is perceived by many Cubans in the island’s countryside as the last straw.

As Protesters Die, a Nation’s Security Forces Face Little Scrutiny (NYT) In the adobe house she built with her husband in a small village in Peru, Antonia Huillca pulled out a stack of documents that once represented a glimmer of hope. They were part of an investigation into the death of her husband, Quintino Cereceda, who left one morning in 2016 to join a protest against a new copper mine and never returned. Ms. Huillca can’t read, but she can identify a photo of her husband’s body, a bullet wound to his forehead; the question-and-answer format in which police officers describe firing live ammunition as protesters threw rocks; the logo of the mining company sending convoys of trucks over unpaved roads, sparking protests among villagers fed up with the dust. But today, the investigation has gone cold. “All these years and no justice,” Ms. Huillca, a 51-year-old Quechua farmer, said. “It’s as if we don’t exist.” For years, scores of similar cases in Peru have met a familiar fate: Investigations into the killing of unarmed civilians at protests where security forces were deployed, most of them in poor Indigenous and rural areas, are opened when they attract headlines, only to be closed quietly later, with officials often citing a lack of evidence. Now, the unusually high death toll during antigovernment demonstrations after the removal of the country’s president last year has put accusations of abuse by security officials in the global spotlight, raising questions about why so many previous killings remain unsolved.

Immigration to Britain reaches record high in 2022 (AP) The number of people moving to Britain reached a record high of more than 600,000 in 2022, government figures showed Thursday. The statistics office said the record level was due to a “series of unprecedented world events throughout 2022 and the lifting of restrictions following the coronavirus pandemic.” As well as people coming to Britain to work, the figure includes tens of thousands of international students and almost 200,000 people who have arrived under special programs for people fleeing war in Ukraine and China’s clampdown in Hong Kong. The high figure will renew debate about Britain’s departure from the European Union, which was motivated in part by the arrival of hundreds of thousands of people from across Europe in the years before the 2016 Brexit referendum.

Europe Faces a Food Shock (WSJ) Fresh out of an energy crisis, Europeans are facing a food-price explosion that is changing diets and forcing consumers across the region to tighten their belts—literally. This is happening even though inflation as a whole is falling thanks to lower energy prices. New data on Wednesday showed inflation in the U.K. fell sharply in April as energy prices cooled, following a similar pattern around Europe and in the U.S. But food prices were 19.3% higher than a year earlier. The continued surge in food prices has caught central bankers off guard and pressured governments to come to the rescue.

Prigozhin’s warning (Washington Post) Fresh off his claim of victory in capturing the Ukrainian city of Bakhmut, Russian mercenary boss Yevgeniy Prigozhin warned that Moscow’s brutal war could plunge Russia into turmoil similar to the 1917 revolution unless its detached, wealthy elite become more directly committed to the conflict. In a lengthy interview with Konstantin Dolgov, a political operative and pro-war blogger, Prigozhin, the founder and leader of the Wagner mercenary group, also asserted that the war had backfired spectacularly by failing to “demilitarize” Ukraine, one of President Vladimir Putin’s stated aims of the invasion. He also called for totalitarian policies. “We are in a situation where we can simply lose Russia,” Prigozhin said, using an expletive to hammer his point. “We must introduce martial law. We unfortunately … must announce new waves of mobilization; we must put everyone who is capable to work on increasing the production of ammunition,” he said. “Russia needs to live like North Korea for a few years, so to say, close the borders … and work hard.” Instead of demilitarization, he said, the invasion turned “Ukraine’s army into one of the most powerful in the world” and Ukrainians into “a nation known to the entire world.”

Turkish voters weigh final decision on next president (AP) Two opposing visions for Turkey’s future are on the ballot when voters return to the polls Sunday for a runoff presidential election that will decide between an increasingly authoritarian incumbent and a challenger who has pledged to restore democracy. President Recep Tayyip Erdogan, a populist and polarizing leader who has ruled Turkey for 20 years, is well positioned to win after falling just short of victory in the first round of balloting on May 14. He was the top finisher even as the country reels from sky-high inflation and the effects of a devastating earthquake in February. Kemal Kilicdaroglu, the leader of Turkey’s pro-secular main opposition party and a six-party alliance, has campaigned on a promise to undo Erdogan’s authoritarian tilt. The 74-year-old former bureaucrat has described the runoff as a referendum on the direction of the strategically located NATO country, which is at the crossroads of Europe and Asia and has a key say over the alliance’s expansion. “This is an existential struggle. Turkey will either be dragged into darkness or light,” Kilicdaroglu said. “This is more than an election. It has turned into a referendum.”

Beijing can’t take a joke (Foreign Policy) A Chinese comedian’s mild joke about the People’s Liberation Army (PLA) last week led to a $1.9 million fine for his entertainment company. Li Haoshi, a stand-up comedian known as “House” onstage, joked that watching his dogs chase a squirrel reminded him of the PLA slogan “Fight to win!” Beijing authorities intervened after audio was shared on social media, fining the company that represents Li and confiscating the profits of weekend shows. Li is now under investigation for insulting the PLA and causing “bad social impact.” Around the same time, China suspended the Weibo and Bilibili accounts of a popular British Malaysian comedian after he made a joke about Chinese surveillance. One of the reasons that Chinese censorship has become so petty is that years of crackdowns under Xi quashed most dissident content years ago. The authorities must now go after the inconsequential to justify their own existence.

South Korea, US troops to hold massive live-fire drills near border with North Korea (AP) The South Korean and U.S. militaries were set to begin massive live-fire drills near the border with North Korea on Thursday, despite the North’s warning that it won’t tolerate what it calls such a hostile invasion rehearsal on its doorstep. Thursday’s drills, the first of the allies’ five rounds of firing exercises until mid-June, mark 70 years since the establishment of the military alliance between Seoul and Washington. North Korea has typically reacted to such major South Korean-U.S. exercises with missile and other weapons tests. Since the start of 2022, North Korea has test-launched more than 100 missiles but none since it fired a solid-fuel intercontinental ballistic missile in mid-April. North Korea has argued its torrid pace of tests was meant to respond to the expanded military drills between the U.S. and South Korea, but observers say the North aims to advance its weapons development then wrest greater concessions from its rivals in eventual diplomacy.

What about those who can’t flee fighting in Sudan? (AP) Mahmoud almost never leaves his small apartment in east Khartoum. Electricity has been out for most of the past month, so he swelters in the summer heat. When he does venture out to find food, he leaves his mobile phone behind because of looters in the street. Otherwise, he hunkers down in fear, worried that an artillery shell could burst into his home. Since the conflict broke out last month, more than 1.3 million people have fled their homes to escape Sudan’s fighting, going elsewhere in the country or across the borders. But Mahmoud and millions of others remain trapped in Khartoum and its sister cities of Bahri and Omdurman, unable to leave the central battleground between Sudan’s military and the Rapid Support Forces paramilitary. For them, every day is a struggle to find food, get water and charge their phones when electricity is cut off. All the while, they must avoid the fighters and criminals in the streets who rob and brutalize pedestrians, loot shops and storm into homes to steal whatever of value they can find.

Paralysis Breakthrough (1440) Swiss neuroscientists have successfully utilized a brain-spine interface to enable a paralyzed man to walk using his thoughts, according to a study released yesterday. The breakthrough development expands on recent innovations using spinal implants to generate movement in patients with immobilizing spinal injuries. Gert-Jan Oskam, a Dutch 40-year-old who was paralyzed 12 years ago, received two brain implants and one on his spine, creating a so-called “digital bridge” across the injured nerves. A portable computer decodes his brain’s electrical signals and relays them to a spinal pulse generator, resulting in the perception that his lower body movements are voluntary. Combined with regular therapy, the procedure allows Oskam to walk and climb stairs with a natural gait aided by a walker, at times without the digital bridge activated. The procedure further opens the possibility for victims of paralysis to regain control of their legs, with researchers hoping to reduce the size and invasiveness of the implants.

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elsewhere on the internet: technology platforms & AI

The Limitations of ChatGPT with Emily Bender and Casey Fiesler

The Radical AI podcast (March 2023)

In this episode, we unpack the limitations of ChatGPT. We interview Dr. Emily M. Bender and Dr. Casey Fiesler about the ethical considerations of ChatGPT, bias and discrimination, and the importance of algorithmic literacy in the face of chatbots.

Emily M. Bender is a Professor of Linguistics and an Adjunct Professor in the School of Computer Science and the Information School at the University of Washington, where she has been on the faculty since 2003. Her research interests include multilingual grammar engineering, computational semantics, and the societal impacts of language technology. Emily was also recently nominated as a Fellow of the American Association for the Advancement of Science (AAAS).

Casey Fiesler is an associate professor in Information Science at University of Colorado Boulder. She researches and teaches in the areas of technology ethics, internet law and policy, and online communities. Also a public scholar, she is a frequent commentator and speaker on topics of technology ethics and policy, and her research has been covered everywhere from The New York Times to Teen Vogue.

Will A.I. Become the New McKinsey? by Ted Chiang (The New Yorker, May 2023)

People who criticize new technologies are sometimes called Luddites, but it’s helpful to clarify what the Luddites actually wanted. The main thing they were protesting was the fact that their wages were falling at the same time that factory owners’ profits were increasing, along with food prices. They were also protesting unsafe working conditions, the use of child labor, and the sale of shoddy goods that discredited the entire textile industry. The Luddites did not indiscriminately destroy machines; if a machine’s owner paid his workers well, they left it alone. The Luddites were not anti-technology; what they wanted was economic justice. They destroyed machinery as a way to get factory owners’ attention.

Whenever anyone accuses anyone else of being a Luddite, it’s worth asking, is the person being accused actually against technology? Or are they in favor of economic justice? And is the person making the accusation actually in favor of improving people’s lives? Or are they just trying to increase the private accumulation of capital?

In 1980, it was common to support a family on a single income; now it’s rare. So, how much progress have we really made in the past forty years? Sure, shopping online is fast and easy, and streaming movies at home is cool, but I think a lot of people would willingly trade those conveniences for the ability to own their own homes, send their kids to college without running up lifelong debt, and go to the hospital without falling into bankruptcy. It’s not technology’s fault that the median income hasn’t kept pace with per-capita G.D.P.; it’s mostly the fault of Ronald Reagan and Milton Friedman. But some responsibility also falls on the management policies of C.E.O.s like Jack Welch, who ran General Electric between 1981 and 2001, as well as on consulting firms like McKinsey. I’m not blaming the personal computer for the rise in wealth inequality—I’m just saying that the claim that better technology will necessarily improve people’s standard of living is no longer credible.

[Image shows Stable Diffusion generated images for “Committed Janitor”]

Researchers Find Stable Diffusion Amplifies Stereotypes by Justin Hendrix (Tech Policy, Nov 2022)

Sasha Luccioni, an artificial intelligence (AI) researcher at Hugging Face, a company that develops AI tools, recently released a project she calls the Stable Diffusion Explorer. With a menu of inputs, a user can compare how different professions are represented by Stable Diffusion, and how variables such as adjectives may alter image outputs. An “assertive firefighter,” for instance, is depicted as white male. A “committed janitor” is a person of color.

A talk: How To Find Things Online by v buckenham (May 2023)

And the other way to look at this, really, is not about AI at all, but seeing this as the continuation of a gradual corporate incursion into the early spirit of sharing that characterised the internet. I say incursion but maybe the better word is enclosure, as in enclosure of the commons. And this positions AI as just a new method by which companies try to extract value from the things people share freely, and capture that value for themselves. And maybe the way back from this is being more intentional about building our communities in ways where the communities own them. GameFAQs was created to collate some useful stuff together for a community, and it ended up as part of a complicated chain of corporate mergers and acquisitions. But other communities experienced the kinds of upheaval that came with that, and then decided to create their own sites which can endure outside of that - I’m thinking here especially of Archive of Our Own, the biggest repository for fan-writing online. And incidentally, the source of 8.2 million words in that AI training set, larger even than Reddit.

The technologies of all dead generations by Ben Tarnoff  (Apr 2023)

The three waves of algorithmic accountability

First wave: Harm reduction

Second wave: Abolition

Third wave: Alternatives

The third wave of algorithmic accountability, then, is already in motion. It’s a welcome development, and one that I wholeheartedly support.

But I’m also wary of it. There is a sense of relief when one moves from critique to creation. It satisfies the familiar American impulse to be practical, constructive, solution-oriented. And this introduces a danger, which is that in the comfort we derive from finally doing something rather than just talking and writing and analyzing and arguing, we get too comfortable, and act without an adequate understanding of the difficulties that condition and constrain our activity.

Platforms don't exist by Ben Tarnoff (Nov 2019)

By contrast, a left tech policy should aim to make markets mediate less of our lives—to make them less central to our survival and flourishing. This is typically referred to as decommodification, and it’s closely related to another core principle, democratization. Capitalism is driven by continuous accumulation, and continuous accumulation requires the commodification of as many things and activities as possible. Decommodification tries to roll this process back, by taking certain things and activities off the market. This lets us do two things: 1. The first is to give everybody the resources (material and otherwise) that they need to survive and to flourish—as a matter of right, not as a commodity. People get what they need, not just what they can afford. 2. The second is to give everybody the power to participate in the decisions that most affect them.

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Nationals demote all-star shortstop CJ Abrams to Class AAA - The Washington Post

Nationals demote all-star shortstop CJ Abrams to Class AAA  The Washington Post Sources: Nats demote All-Star after all-nighter  ESPN Nationals All-Star demoted to minor leagues after staying at casino overnight: reports  Fox News Nationals demote All-Star CJ Abrams after reported late night out at casino  Yahoo Sports Nationals option All-Star Abrams to Triple-A due to ‘internal…