scidocpublishers

[scidocpublishers]

Premature Puberty in Obese Female Children Aged 5-17 in the United States

Premature Puberty in Obese Female Children Aged 5-17 in the United States - Latest #research article published in #IJCDT journal.

For Info https://scidoc.org/IJCDT-2572-7613-04-201

The prevalence of obesity in female children in the #UnitedStates has increased from 5% to 17.1% from 1965 to 2015 and the prevalence of premature puberty has increased as well. Increased weight is correlated with premature puberty in females and interestingly, different studies have shown that there has been a gradual decline in age for onset of puberty.

Early sexual maturation in female children are associated with many negative consequences such as increased risk of adult obesity, type 2 diabetes, increased aggression, increased adolescent risk taking behaviors, increased sexual activity, and breast cancer.

[scidocpublishers]

Sensory Evaluation of Gamma Irradiated shrimp

*Latest Research highlights the Sensory Evaluation of Gamma Irradiated shrimp (Penaeus notalis) from Three Different Water Sources in Ghana published in our IJFS Journal.*

For Info: https://scidoc.org/IJFS-2326-3350-07-301

Shrimp is one of the world’s most popular shellfish. It is cherished in Ghana due to a wide range of culinary applications such as its use as food as well as food condiments in some local foods such as kenkey (local food prepared from fermented corn dough), pepper sauce (locally called shito), fast foods etc.

The influence of gamma irradiation on the sensory and acceptability attributes of dried shrimp was evaluated. Sensory evaluation was carried out using steamed shrimp samples irradiated at doses 0 (control), 4, 8 and 10 kGy at a dose rate of 2.71 kGy/hr from a Cobalt 60 source (SLL 515, Hungary) batch irradiator and stored in polypropylene packs for 4 months at 28-30°C. Using a structured questionnaire, 30 male and female panelists independently assessed the samples for sensory attributes. Organoleptic scores were made according to a seven-point hedonic scale and a mean score of 4 used as the acceptable limit.

[scidocpublishers]

An Overview on Oncolytic Viruses as Cancer Therapy

The current regimen of cancer therapy (chemotherapy and radiotherapy) suffers from disadvantages such as narrow therapeutic index that further facilitates tumor evolves drug resistance and severe side-effects. Oncolytic viruses are therapeutically useful anticancer viruses that will selectively infect and damage cancerous tissues without causing harm to the normal tissues.

Many naturally occurring Oncolytic viruses have a preferential tropism to a tumor or associated endothelial cells and others are genetically engineered to change their cellular or organ tropism toward cancer. Antitumor effect of Oncolytic viruses is either by locale cell death or by initiation of the systemic immune response against the tumor.

Oncolytic Adenovirus, Herpes Simplex Virus, Newcastle Disease Virus, and Reovirus are representative of Oncolytic viruses that have potential to lysis tumor. The effects of the host immune response on the efficacy of Oncolytic viruses are complex. But, using of carrier cells as delivery vehicles could hide the viral antigen from antibodies and complements.

Oncolytic viruses have been combined with many cancer therapies to increase response to cancer. Since many forms of canine or feline neoplasms resemble humane counterpart. So, oncologists believe that Oncolytic virotherapy could soon be a reality in veterinary medicine.

Cancer is one of the leading causes of death in worldwide. Despite significant progress made in cancer therapies, but mortality rates for most malignancies remain terrifyingly high. Cancer results either due to decreased cell death or increased cell birth. The inhibition of cancer growth and succession is one of the major challenges faced by modern medicine. The classical regimen of cancer therapy (chemotherapy and radiotherapy) suffers from disadvantages such as narrow therapeutic index that further facilitates tumor evolves drug resistance and severe side-effects.

The current goal for developing new therapies for the treatment of cancer is to design therapeutic agents that have a large therapeutic index (i.e. high potency against malignant cells) with little or no toxicities to normal cells. Future treatment modalities need to be more selective and specific which allowing effective drug doses reach to each tumor cell.

Oncolytic viruses are therapeutically useful anticancer viruses that will selectively infect and damage cancerous tissues without causing harm to the normal tissues. Each virus has a specific cellular tropism that determines which tissues are preferentially infected. The field of Oncolytic virotherapy began as an observational science more than a century ago, when it was noted that cancer regressions sometimes occurred spontaneously in patients following certain viral infections. Most people think of viruses as pathogenic microorganisms that infect cells, overtake their DNA, RNA and protein synthetic machinery to replicate and then lyse their host cell to spread their progeny, thereby propagating the infection throughout a tissue. Viral infection also results in cytopathic effects, such as induction of cell death and dysfunction.

With the advent of modern biotechnology tools and better understanding of cancer biology and virology, it has become feasible to engineer viruses with increased tumor selectivity and enhanced oncolytic activity. Naturally occurring lytic viruses have evolved to infect, replicate and lyse cells. It is interesting that the replication cycle of many viruses exploits the cellular pathways that are altered in cancer cells.

The anticancer activities of OVs are derived from multimodal cancer-killing mechanisms. The first is the direct oncolysis of cancer cells by the virus. The second is apoptotic and necrotic death of uninfected cells induced by anti-angiogenesis and antivas culture of the Oncolytic viruses as shown in animals and humans. The last is cytotoxicity to cancer and stromal cells by activated innate and tumor-specific immune cells.

Read more at An Overview on Oncolytic Viruses as Cancer Therapy published in IJCR Journal.

[scidocpublishers]

Journal of Computational & Neural Engineering

International Journal of Computational & Neural Engineering peer-reviewed journal discusses various new issues and developments in different areas of #neuroscience.

For Info https://scidoc.org/computational-and-neural-engineering

Thorough Review - Fast Publishing. Gain More Benefits*

[scidocpublishers]

Latest research paper on dentistry

Latest research paper on #dentistry in our Journal - #IJDOS

International Journal of Dentistry and Oral Science (IJDOS) is to provide a purpose of bringing scientific research, newer techniques and opinions to a wider audience of dental professionals around the globe in order to improve the clinical outcome of dental treatment.

(Fast Review, Publishing & Printing International Journal)

For Info https://scidoc.org/ArchiveIJDOS

[scidocpublishers]

Clinical Pharmacology & Toxicology - Journal

#IJCPT -  International Journal of Clinical Pharmacology & Toxicology A peer-reviewed journal that publishes papers in the field of Pharmacology and Toxicology.

Read and share articles of IJCPT.

For Info https://scidoc.org/clinical-pharmacology-and-toxicology

[scidocpublishers]

Special Issues - List of Journals

Scholarly articles available in our Special issues Science Journal. Here is List of journals which are having special issues.

For Info

https://scidoc.org/specialissues

Special Issue is a referred collection of articles and research, on a predetermined theme which serves as an effective way to communicate current knowledge, to the researchers, thereby propagating their ideas for the betterment of Society.

SciDocPublishers invites proposals for Special Issues that falls within the aims and scopes of the journals published by Us.

[scidocpublishers]

International Journal of cancer

International Journal of cancer

An open access peer-reviewed journal devoted to cancer studies and research. Doing any research on #cancer?. If yes, you can submit your work to our journal.

Here's Link: https://scidoc.org/cancer-studies-and-research

[scidocpublishers]

special issues - journal of diabetology

Access our special issues to cover a variety of topics relevant to #diabetes in our International Journal of Diabetology & Vascular Disease Research.

For Info: https://scidoc.org/IJDVRSpecialIssues

Submit your research today!

[scidocpublishers]

International Journal of anatomy

International Journal of anatomy and Applied Physiology - publishes original research/ reviews from leading scientists and scholars around the world.

For Info: https://scidoc.org/anatomy-applied-physiology

IJAAP brings scientific findings, new techniques, and opinions on anatomy and physiological research to a wide audience of scholars, educators, and information specialists around the globe.

[scidocpublishers]

A Yellow and Benign Tumor in a Newborn - Case report

A Yellow and Benign Tumor in a Newborn - case study published in IJPA Journal.

Read more@ https://scidoc.org/IJPA-2572-7354-05-202

The sebaceous hamartoma of Jadassohn (HSJ) is a congenital malformation most often discovered during infancy. Early surgical excision is motivated by the rare risk of malignant tumor development, especially basal cell carcinoma during puberty. We report the case of a Jadassohn Hamartoma.

[scidocpublishers]

Design and Experimental Analysis of a Cetirizine Hydrochloride Drug Sensor

Design and Experimental Analysis of a Cetirizine Hydrochloride Drug Sensor

A cetirizine hydrochloride PVC membrane drug sensor was developed by using the ion association complex produced with sodium tetra phenyl borate and cetirizine hydrochloride as electroactive substance. In sodium dihydrogen phosphate-sodium hydroxide buffer solution of pH 5.0, the linear range of the sensor is 1.58×10-6~1.0×10-1 mol/L, the slope is 46mV/pC (20°C) and the detection limit is…

[scidocpublishers]

Histological and CD31 Immunolocalization after Pulp Therapy

Histological and CD31 Immunolocalization after Pulp Therapy using Mta or Portland Cement - research article published in #IJDOS journal.  (Vol 5, Issue 3)

Read more @ https://scidoc.org/IJDOS-2377-8075-05-303

In cases of deep caries or trauma of primary teeth, a #pulpotomy is the procedure of choice to preserve pulp vitality and the teeth. This study aimed to evaluate the histological analysis and CD31 immunolocalization after pulpotomy using Mineral Trioxide Aggregate or Portland cement in human primary teeth.

Twenty mandibular primary molars were divided into two study groups: G1 - Mineral Trioxide Aggregate and G2 - Portland cement.

[scidocpublishers]

International Journal of chronic diseases

International Journal of chronic diseases - an open access journal dedicated to publishing articles in all areas of Chronic Diseases.

Know more @ https://scidoc.org/chronic-diseases-and-therapy

It provides a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of Chronic Diseases & Therapy. 

[scidocpublishers]

World optometry day - SciDoc Publishers

Happy World Optometry Day to all optometrists. All join hands to raise awareness in eye care. Here's a Journal to publish research on uncorrected refractive errors.

know more @ https://scidoc.org/ophthalmology-and-eye-science

#WorldOptometryDay #WorldOptometryWeek #Optometry #IJOES #SciDocPublishers

[scidocpublishers]

Journal of HIV - SciDoc Publishers

Doing research on HIV?. Here's International Journal of HIV/AIDS and Research to submit your work.

For Info: https://scidoc.org/hiv-aids-and-research

IJHR is and open access journal, provides a clinically oriented forum for investigating and treating sexually transmissible infections, HIV and #AIDS thereby publishing the very latest groundbreaking research on HIV and AIDS.

[scidocpublishers]

Sliced Conchal Cartilage Versus Temporalis Muscle Fascia Graft In Type I Tympanoplasty

A Comparative Evaluation of Audiological and Graft Uptake Results of Reinforced Sliced Conchal Cartilage Versus Temporalis Muscle Fascia Graft In Type I Tympanoplasty - research article published in IJCEO Journal. Vol 4, Issue 1, 2018.

For Info https://scidoc.org/IJCEO-2572-732X-04-101

The present study aims to evaluate graft uptake rates and audiological results of type I tympanoplasty using sliced conchal cartilage reinforced with temporalis muscle fascia versus temporalis muscle fascia graft.